Hub : Genes

Zfp790

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Zfp790	0.04	0.03	3.7e-04	0.01	0	0	0.01	4.3e-02	8.2e-02	1.1e-01	2.4e-02
2	Eye	mRNA stability	Zfp790	0.39	0.23	2.9e-03	0.08	0	-0	-0.01	2.7e-02	3.0e-01	3.8e-01	6.1e-01
3	Eye	gene expression	Zfp790	0.72	0.2	1.7e-03	0.06	0.03	0.05	0	5.1e-02	1.3e-01	5.7e-02	3.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.3	0.4	1.1	0.3	1.1	0.2
Area under the delay curve	0.9	1.0	1.3	-1.2	0.7	1.0
BMI with tail	0.3	0.9	1.3	1.2	-0.7	-0.9
BMI without tail	0.2	0.3	0.4	-0.4	0.6	0.7
Body weight	2.3	9.5	11.5	-2.9	3.4	2.9
Weight adjusted by age	0.2	0.2	0.3	0.6	0.2	-0.4
Bone surface	0.9	1.6	3.2	-0.7	1.8	1.0
Bone volume	0.8	1.3	2.8	-0.6	1.7	0.9
Breakpoint value in progressive ratio session	2.9	3.2	4.8	-1.8	1.2	2.2
Number of licking bursts	3.5	4.2	4.7	1.8	-2.1	-2.2
Context. condit. distance diff. score	0.1	0.1	0.1	0.2	-0.4	0.0
Locomotion velocity, session 1	0.8	0.9	1.1	1.1	-0.9	-0.9
Locomotion distance, session 1	0.6	0.7	1.3	-1.2	0.6	0.7
Locomotion velocity, session 2	0.4	0.4	0.7	0.9	-0.7	-0.4
Locomotion distance, session 2	1.3	1.8	1.9	1.3	-1.3	-1.4
Locomotion velocity, session 3	0.4	0.5	0.7	0.9	-0.6	-0.6
Locomotion distance, session 3	3.3	3.6	4.0	-2.0	1.7	2.0
Stereotopy head waving bouts, day 3	1.2	1.4	2.5	1.6	-0.7	-1.1
Stereotopy head waving duration, day 3	2.3	2.7	4.5	2.1	-1.2	-1.5
Locomotion velocity, session 7	0.1	0.1	0.3	0.0	0.5	0.4
Locomotion distance, session 7	0.0	0.1	0.1	-0.2	0.3	0.2
Stereotopy head waving bouts, day 7	0.7	0.8	1.1	0.8	-1.0	-0.8
Stereotopy head waving duration, day 7	2.1	2.5	2.9	1.6	-1.7	-1.5
Locomotion velocity, session 8	4.4	5.3	6.0	2.4	-2.2	-2.2
Locomotion distance, session 8	0.7	1.0	1.4	0.8	-1.2	-0.9
Degree of sensitization distance	1.0	1.0	1.6	1.3	-0.7	-1.0
Degree of sensitization stereotypy	0.8	0.9	1.3	0.6	-1.2	-1.0
Conditioned locomotion	0.3	0.4	0.7	0.4	-0.9	-0.6
Cocaine response after cond. corrected	0.0	0.0	0.0	-0.1	-0.2	0.2
Cocaine response after cond. not corrected	0.0	0.0	0.0	0.0	-0.0	0.1
Cocaine response before conditioning	0.7	0.8	1.7	-0.4	1.3	0.7
Saline control response	0.1	0.2	0.4	-0.6	0.1	0.3
Bone: connectivity density	0.2	0.3	0.6	0.6	0.8	-0.1
Bone: cortical apparent density	2.5	3.3	3.6	1.8	-1.8	-1.9
Bone: cortical area	1.4	2.1	2.5	-1.5	1.6	1.2
Bone: cortical porosity	2.1	2.3	3.4	1.8	-0.9	-1.6
Bone: cortical porosity	2.5	2.8	3.9	2.0	-1.2	-1.7
Bone: cortical thickness	0.3	0.5	0.8	-0.9	0.7	0.4
Bone: cortical thickness	0.9	1.1	1.4	1.1	-0.9	-1.2
Bone: cortical tissue density	2.9	3.8	4.1	1.9	-1.9	-2.0
Condit. Reinf. active minus inactive responses	0.2	0.2	0.3	0.5	-0.6	-0.3
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.5	-0.4	-0.2
Condit. Reinf. active responses	1.9	2.3	3.1	1.4	-1.8	-1.4
Condit. Reinf. inactive responses	1.9	2.2	3.2	1.1	-1.8	-1.5
Incentive salience index mean	0.1	0.1	0.2	0.3	-0.5	-0.1
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.3	0.1	0.5
Condit. Reinf. active minus inactive responses	3.0	3.7	4.6	-2.1	1.4	2.1
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.7	-0.9	-0.3	0.6
Condit. Reinf. active responses	4.6	6.3	6.7	-2.6	2.4	2.6
Condit. Reinf. inactive responses	4.1	5.0	6.9	-2.0	2.6	2.0
Condit. Reinf. lever presses	9.0	12.2	13.9	-3.7	3.3	3.4
Condit. Reinf. lever reinforcers received	4.7	6.7	7.4	-2.7	2.4	2.6
Conditioned reinforcement - actives	0.3	0.3	0.5	-0.3	-0.7	-0.6
Conditioned reinforcement - inactives	0.8	0.9	2.0	-1.4	0.7	0.6
Conditioned locomotion	2.5	3.0	3.7	1.6	-1.9	-1.7
Patch foraging indifference point 0 sec	0.2	0.3	0.5	-0.6	0.7	0.1
Patch foraging indifference point AUC	0.4	0.5	0.6	0.7	-0.6	-0.8
Delay disc. indifference point, 0s delay	0.7	0.8	1.7	-1.3	-0.2	0.7
Delay disc. indifference point, 16s delay	2.8	2.8	3.9	-2.0	1.2	1.8
Delay disc. indifference point, 2s delay	1.0	1.1	1.8	-1.3	0.9	0.9
Delay disc. indifference point, 24s delay	3.3	3.2	3.5	-1.7	1.9	1.8
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	-0.6	-0.1	0.3
Delay disc. indifference point, 8s delay	0.2	0.2	0.5	0.1	0.7	0.4
Indifference point function ln k	0.6	0.8	1.3	-0.9	0.6	1.1
Indifference point function log k	0.6	0.8	1.3	-0.9	0.6	1.1
Patch foraging total patch changes 0 sec	0.3	0.5	0.8	-0.8	0.9	0.3
Patch foraging total patch changes 12 sec	0.1	0.2	0.3	-0.6	0.3	0.3
Patch foraging total patch changes 18 sec	0.2	0.2	0.6	0.3	0.1	-0.8
Patch foraging total patch changes 24 sec	1.0	1.2	1.7	-1.3	1.2	0.7
Patch foraging total patch changes 6 sec	0.2	0.2	0.5	-0.2	0.7	-0.3
Patch foraging time to switch 0 sec	0.5	0.7	1.1	1.0	-0.9	-0.5
Patch foraging water rate 0 sec	0.8	1.3	2.0	1.2	-0.7	-1.4
Patch foraging water rate 12 sec	0.5	0.7	1.2	-1.1	0.8	0.5
Patch foraging water rate 18 sec	0.2	0.3	0.5	0.5	-0.3	-0.7
Patch foraging water rate 24 sec	0.0	0.0	0.1	-0.3	-0.1	-0.1
Patch foraging water rate 6 sec	0.7	1.0	1.9	-0.6	1.4	0.9
Seeking ratio, delayed vs. immediate footshock	1.3	1.4	1.9	-1.4	1.0	1.2
Distance traveled before self-admin	0.5	0.5	1.0	-1.0	-0.3	0.7
Distance traveled after self-admin	4.8	5.3	6.9	-2.6	2.1	2.1
Extensor digitorum longus weight	0.2	0.6	0.7	0.8	-0.7	-0.8
Bone: elastic displacement	0.0	0.0	0.1	0.1	-0.1	-0.3
Bone: elastic work	1.6	2.1	2.4	-1.4	1.6	1.4
Bone: endosteal estimation	1.8	3.9	4.1	-1.9	2.0	2.0
Bone: endosteal perimeter	1.9	3.9	4.4	-2.0	1.8	2.1
Epididymis fat weight	0.0	0.0	0.1	0.1	0.3	-0.0
Delta time in closed arm before/after self-admin	2.1	2.0	3.0	-0.9	1.7	1.5
Delta time in open arm before/after self-admin	0.6	0.5	1.1	0.5	-0.5	-1.0
Diff in mean of infusions in LGA sessions	0.2	0.2	0.5	-0.4	-0.7	0.4
Delay discount exponential model param	1.0	1.1	1.3	1.1	-0.9	-1.0
Extinction: sum of active levers before priming	3.4	3.4	4.5	-1.4	1.9	2.1
Active lever presses in extinction session 6	2.6	2.6	3.6	-1.2	1.7	1.9
Bone: final force	1.5	2.4	3.4	-1.4	1.8	1.3
Bone: final moment	2.0	3.3	4.3	-1.7	2.1	1.6
Food consumed during 24 hour testing period	0.8	1.0	1.1	-1.0	1.0	0.9
Glucose	0.2	0.3	0.3	0.6	-0.5	-0.5
Heart weight	0.2	0.3	0.5	-0.6	0.2	0.7
Delay discount hyperbolic model param	0.7	0.8	1.1	1.1	-0.7	-0.8
Intermittent access intake day 1-15 change	2.0	2.0	2.8	-1.7	1.3	1.2
Intermittent access intake escalation	1.9	1.8	2.3	-1.5	1.3	1.2
Intermittent access intake escalation 2	2.2	2.2	3.4	-1.8	1.0	1.4
Intermitt. access day 1 inactive lever presses	3.8	4.1	5.2	-1.5	2.2	2.3
Intermitt. access day 15 inactive lever presses	0.8	0.8	1.1	-0.8	0.9	1.0
Intermitt. access escalation Index	0.1	0.1	0.2	0.2	-0.5	-0.2
Intermittent access day 1 total infusions	2.1	2.4	3.4	1.1	-1.9	-1.6
Intermittent access day 15 total infusions	0.2	0.3	0.5	-0.7	-0.6	0.0
Intermittent access terminal intake (last 3 days)	0.5	0.5	0.9	-0.8	-1.0	-0.1
Intermittent access total infusions	0.5	0.6	1.4	-0.1	-1.2	-0.5
Intermittent access day 1 locomotion	0.9	1.0	1.5	0.7	-1.2	-0.9
Intermittent access day 15 total locomotion	0.1	0.1	0.2	0.1	-0.4	-0.3
Intermittent access total locomotion	1.1	1.3	2.2	0.9	-1.5	-1.0
Intermittent access standard deviation	5.9	6.3	8.5	-2.9	2.1	2.4
Left kidney weight	1.7	4.8	6.8	-1.7	2.6	2.1
Right kidney weight	3.9	10.9	12.8	-2.8	3.6	3.5
Cocaine induced anxiety	0.5	0.6	1.1	-0.2	0.8	1.1
Post-drug Anxiety	0.0	0.0	0.0	0.2	-0.1	0.2
Baseline Anxiety	1.1	1.1	1.7	0.7	-1.1	-1.3
Tail length	5.6	17.1	18.6	-4.3	4.1	4.0
Length with tail	7.9	29.1	30.2	-5.5	5.5	5.2
Length without tail	3.9	8.6	11.7	-2.7	3.4	2.6
Times rat made contact with spout	1.3	1.5	2.1	1.2	-1.0	-1.4
Lifetime Intake	0.7	0.8	1.7	0.4	-1.3	-0.8
Liver weight, left	0.6	1.0	1.5	1.0	-0.7	-1.2
Liver weight, right	0.1	0.1	0.3	0.1	-0.1	-0.6
Locomotor activity	0.7	1.1	1.8	1.3	-0.6	-1.0
Locomotor testing distance	0.6	0.9	1.6	1.3	-0.6	-0.9
Locomotor testing rearing	2.4	3.8	4.5	2.0	-1.7	-2.1
Locomotion in novel chamber	0.0	0.1	0.1	0.2	-0.4	0.1
Locomotion in novel chamber post-restriction	0.5	0.6	1.0	-0.9	0.0	1.0
Fecal boli incidents, locomotor time 1	1.8	1.9	3.2	1.3	-1.8	-0.9
Change in fecal boli incidents, locomotor task	0.3	0.2	0.6	-0.2	0.7	0.3
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.0	0.2	-0.1	0.1
Bouts of movement, locomotor time 1	1.1	1.2	2.5	-1.6	0.3	1.0
Total resting periods, locomotor time 1	1.1	1.2	2.5	-1.6	0.2	1.1
Rest time, locomotor task time 1	0.5	0.5	1.4	0.1	-1.2	-0.3
Distance moved, locomotor task time 1	0.1	0.2	0.2	0.3	0.5	-0.4
Vertical activity count, locomotor time 1	1.7	1.8	4.0	-0.7	2.0	0.9
Time >=10cm from walls, locomotor time 2	0.9	1.0	2.1	0.2	-1.4	-0.9
Bouts of movement, locomotor time 2	0.1	0.1	0.2	-0.5	-0.3	0.1
Total resting periods, locomotor time 2	0.0	0.0	0.1	-0.3	-0.3	0.0
Rest time, locomotor task time 2	0.1	0.1	0.4	-0.1	-0.6	-0.2
Distance moved, locomotor task time 2	0.4	0.4	1.0	0.5	-0.0	-1.0
Vertical activity count, locomotor time 2	0.6	0.7	1.3	-0.6	1.1	0.6
Light reinforcement 1	0.1	0.3	0.6	0.2	-0.3	-0.8
Light reinforcement 2	3.4	4.5	6.3	2.5	-1.9	-1.9
Bone: marrow area	1.8	4.0	4.3	-1.9	2.1	2.0
Bone: maximum diameter	1.3	2.4	2.9	-1.5	1.7	1.4
Bone: maximum force	2.6	4.5	5.2	-2.1	2.3	1.9
Bone: maximum moment	3.2	5.6	6.1	-2.4	2.5	2.2
Mean time between licks in bursts	0.1	0.1	0.2	-0.1	0.2	0.4
Mean num. licks in bursts	0.8	0.9	1.2	-0.8	1.1	1.0
Cd content in liver	0.0	0.0	0.1	0.2	0.0	-0.2
Co content in liver	0.7	0.8	1.9	1.4	-0.4	-0.7
Cu content in liver	0.5	0.6	0.9	-0.9	1.0	0.4
Fe content in liver	0.0	0.0	0.0	0.2	-0.1	-0.1
K content in liver	0.1	0.1	0.1	-0.2	0.3	0.3
Mg content in liver	0.3	0.3	0.5	0.6	-0.5	-0.7
Mn content in liver	0.9	1.1	1.4	1.0	-0.9	-1.2
Na content in liver	2.7	2.8	3.6	-1.9	1.2	1.9
Rb content in liver	0.0	0.0	0.0	-0.1	-0.1	-0.1
Se content in liver	8.5	10.4	11.0	3.3	-3.1	-3.3
Sr content in liver	0.8	0.8	1.1	1.0	-0.8	-0.8
Zn content in liver	0.1	0.1	0.3	0.5	0.0	-0.3
Bone: minimum diameter	4.2	7.9	9.2	-3.0	2.5	2.8
Time in familiar zone, hab. session 1	0.3	0.3	0.3	-0.6	0.5	0.5
Time in novel zone, hab. session 1	0.8	0.8	1.0	0.6	-1.0	-1.0
Total zone transitions, hab. session 1	0.1	0.2	0.5	-0.7	-0.1	0.2
Total locomotion distance, hab. session 1	2.5	3.6	6.1	-2.5	1.3	1.7
Locomotion velocity, hab. session 1	1.4	2.0	3.2	-1.8	1.0	1.3
Time in familiar zone, hab. session 2	2.5	2.6	3.0	-1.4	1.7	1.6
Time in novel zone, hab. session 2	1.7	1.7	2.0	1.1	-1.4	-1.4
Total zone transitions, hab. session 2	2.0	2.5	3.8	1.1	-2.0	-1.6
Total locomotion distance, hab. session 2	0.1	0.1	0.3	-0.5	-0.3	-0.0
Locomotion velocity, hab. session 2	0.1	0.1	0.1	-0.3	-0.4	-0.2
Novel to familiar place preference ratio	0.4	0.4	0.9	-1.0	0.3	0.5
Novelty place preference	0.3	0.3	0.8	-0.9	0.2	0.4
Time in novel zone, NPP test	0.1	0.1	0.4	-0.6	-0.0	0.2
Total zone transitions, NPP test	0.1	0.1	0.2	0.2	-0.3	-0.5
Total locomotion distance, NPP test	2.6	3.6	4.4	-2.1	1.8	1.7
Locomotion velocity, NPP test	2.9	4.1	5.1	-2.3	2.0	1.8
Intraocular pressure	0.0	0.1	0.1	-0.3	-0.3	0.2
Delta distance traveled before/after self-admin	4.1	4.4	7.2	-1.8	2.7	1.7
Delta ambulatory time before/after self-admin	3.8	4.2	7.6	-1.6	2.8	1.6
Parametrial fat weight	0.6	1.1	2.3	1.5	-0.1	-1.0
Pavlov. Cond. lever latency	0.1	0.1	0.2	-0.3	0.3	0.4
Pavlov. Cond. magazine entry latency	0.3	0.4	0.6	0.3	-0.6	-0.8
Pavlov. Cond. change in total contacts	0.1	0.1	0.1	0.1	-0.4	-0.2
Pavlov. Cond. index score	0.3	0.4	0.6	0.6	-0.6	-0.8
Pavlov. Cond. latency score	0.1	0.2	0.2	0.4	-0.4	-0.4
Pavlov. Cond. lever contacts	0.1	0.1	0.2	-0.5	0.3	0.3
Pavlov. Cond. magazine entry number	0.4	0.5	0.8	-0.4	0.7	0.9
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.3	0.8	-1.1	-0.4
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.7	0.5	-0.7	-0.9
Pavlov. Cond. response bias	0.1	0.1	0.1	-0.0	-0.3	-0.4
Pavlov. Cond. lever latency	5.1	6.8	7.1	2.6	-2.6	-2.7
Pavlov. Cond. magazine entry latency	3.5	4.0	4.5	-2.0	1.9	2.1
Pavlov. Cond. change in total contacts	9.0	12.4	14.1	-3.5	3.3	3.8
Pavlov. Cond. index score	5.4	6.9	7.5	-2.6	2.5	2.7
Pavlov. Cond. latency score	5.2	6.5	7.1	-2.5	2.4	2.7
Pavlov. Cond. lever contacts	4.6	6.2	6.6	-2.5	2.4	2.6
Pavlov. Cond. magazine entry number	3.8	4.7	5.4	2.1	-2.0	-2.3
Pavlov. Cond. intertrial magazine entries	1.8	2.3	3.3	1.7	-0.9	-1.8
Pavlov. Cond. lever-magazine prob. diff.	5.3	6.7	7.0	-2.6	2.5	2.6
Pavlov. Cond. response bias	5.2	7.1	7.7	-2.7	2.5	2.8
Time in closed arm before self-admin	2.2	2.5	3.3	1.0	-1.8	-1.7
Time in closed arm after self-admin	0.2	0.2	0.5	-0.3	0.0	0.7
Time in open arm before self-admin	3.4	3.7	5.6	-1.3	2.4	2.0
Time in open arm after self-admin	0.8	0.9	2.1	-0.4	1.5	0.5
Bone: periosteal estimation	2.1	4.3	4.9	-2.0	2.2	2.0
Bone: periosteal perimeter	2.0	3.3	4.0	-2.0	1.5	1.9
Bone: post-yield work	1.9	2.6	2.8	-1.7	1.6	1.5
Progressive ratio test 1 active lever presses	0.2	0.2	0.4	-0.6	0.3	0.5
Progressive ratio test 1 breakpoint	0.5	0.6	0.7	-0.8	0.5	0.8
Progressive ratio test 1 inactive lever presses	0.5	0.5	0.9	-0.9	0.5	0.7
Progressive ratio test 2 active lever presses	0.3	0.3	0.5	-0.7	-0.5	0.2
Progressive ratio test 2 breakpoint	0.2	0.3	0.4	-0.6	-0.6	0.1
Progressive ratio test 2 inactive lever presses	2.5	2.9	5.5	-2.3	0.3	1.7
Incentive Sensitization - Responses	0.3	0.3	0.6	-0.4	-0.8	0.1
Incentive Sensitization - Breakpoint	0.2	0.2	0.6	-0.2	-0.8	-0.0
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	0.0	0.3	0.6
Progressive ratio	0.0	0.0	0.0	0.0	0.0	0.2
Food seeking constrained by brief footshock	3.8	4.7	5.2	-2.3	2.1	2.1
Seeking ratio, punishment vs. effort	0.9	1.1	1.4	-1.2	1.0	0.9
Retroperitoneal fat weight	1.9	6.2	7.3	2.5	-2.3	-2.7
Reaction time number correct	0.2	0.3	0.4	0.7	-0.2	-0.6
Reaction time mean minus median	0.3	0.4	1.0	-0.3	1.0	0.2
Reaction time mean minus median AUC	0.5	0.7	1.9	-0.3	1.4	0.1
Reaction time num false alarms	1.3	1.7	2.1	1.4	-1.2	-1.3
Reaction time num false alarms AUC	1.5	2.1	2.7	1.7	-1.3	-1.4
Reaction time trials correct on left	0.2	0.3	0.4	0.7	-0.2	-0.6
Reaction time trials on left	0.2	0.3	0.5	0.7	-0.2	-0.7
Reaction time mean	0.1	0.1	0.2	0.4	0.4	-0.2
Reaction time mean AUC	0.2	0.3	0.6	0.8	0.3	-0.4
Median of all reaction times	0.1	0.2	0.4	0.6	0.0	-0.3
Reaction time omissions	0.4	0.6	1.0	1.0	0.1	-0.9
Reaction time false alarm rate	0.6	0.9	1.0	1.0	-1.0	-0.7
Reaction time premature initiation rate	0.2	0.2	0.4	-0.6	0.5	0.3
Reaction time premature initiations	0.0	0.1	0.1	-0.1	0.3	-0.2
Std. dev. reaction times	0.3	0.4	1.1	-0.0	1.1	0.1
Reaction time trials completed	0.2	0.3	0.5	0.7	-0.2	-0.7
Reaction time trials AUC	0.4	0.5	0.8	0.9	-0.3	-0.8
Run reversals in cocaine runway, females	0.2	0.2	0.4	0.2	0.7	-0.1
Run reversals in cocaine runway, males	0.8	0.8	2.3	1.5	-0.0	-0.4
Latency to leave start box in cocaine runway	0.1	0.1	0.2	0.3	0.4	-0.2
Latency to leave start box in cocaine runway, F	0.3	0.3	0.6	0.8	0.1	-0.6
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	-0.4	0.3	-0.0
Std. dev. time between licks in bursts	1.2	1.4	2.2	-1.1	0.9	1.5
Total sessions with >9 infusions	1.6	1.8	2.2	1.3	-1.2	-1.5
Short access day 1 total inactive lever presses	0.6	0.7	1.6	-1.3	0.1	0.7
Short access day 10 total inactive lever presses	2.2	2.4	3.6	-1.5	1.2	1.9
Short access day 1 total infusions	0.1	0.1	0.2	0.1	-0.5	-0.3
Short access day 10 total infusions	0.7	0.8	0.9	0.8	-0.9	-0.8
Short access total infusions	1.4	1.6	1.9	1.2	-1.4	-1.2
Short access day 1 locomotion	1.6	1.7	3.2	1.8	-0.6	-1.3
Short access day 10 total locomotion	0.6	0.6	0.9	-0.5	0.8	1.0
Short access total locomotion	1.1	1.1	1.2	1.1	-1.0	-1.1
One hour access (0.3 mA shock)	1.1	1.3	2.2	-1.5	0.8	1.0
Compulsive drug intake	0.3	0.3	0.7	-0.8	0.3	0.1
One hour access (shock baseline)	0.1	0.1	0.1	-0.4	-0.2	0.2
Social response proportion	2.4	2.6	3.3	-1.5	1.5	1.8
Social responses	0.7	0.9	1.7	-0.4	1.3	0.9
Social time	1.9	2.6	3.4	-1.4	1.8	1.6
Soleus weight	0.3	0.7	1.3	0.9	-0.4	-1.1
Bone: stiffness	1.4	2.2	2.3	-1.5	1.5	1.4
Tibialis anterior weight	0.0	0.1	0.2	0.2	-0.2	-0.5
Time to tail flick, vehicle, before self-admin	0.8	0.8	1.1	0.6	-1.1	-1.0
Time to tail flick, vehicle, after self-admin	0.3	0.3	0.8	-0.9	0.0	0.5
Time to tail flick, test, before self-admin	0.9	0.8	1.7	0.7	-0.6	-1.3
Time to tail flick, test, after self-admin	0.3	0.4	0.6	0.7	-0.1	-0.8
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	0.9	-0.7	1.0	0.7
Delta time to tail flick, test, before/after SA	0.1	0.1	0.2	0.4	-0.2	-0.4
Tibia length	2.1	5.9	7.4	-2.0	2.7	2.5
Ambulatory time before self-admin	0.3	0.4	0.6	-0.8	-0.3	0.6
Ambulatory time after self-admin	7.5	8.2	8.6	-2.9	2.9	2.8
Bone: tissue strength	3.8	3.7	4.3	-2.1	2.0	1.7
Total heroin consumption	0.9	1.1	1.7	-1.3	0.5	1.1
Bone: trabecular number	0.7	1.2	2.5	-0.4	1.6	0.9
Bone: trabecular spacing	0.8	1.0	1.8	-1.3	0.5	1.0
Bone: trabecular thickness	0.4	0.5	1.0	1.0	-0.3	-0.7
Bone: trabecular tissue density	2.7	3.8	4.0	2.0	-2.0	-1.9
Water consumed over 24 hours	0.2	0.2	0.5	-0.3	0.7	0.3
Number of responses in last shaping day	0.4	0.4	0.8	-0.9	-0.5	0.4