Hub : Genes

Zfp74

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Zfp74 0.09 0.06 3.0e-08 0.07 0.06 0.07 0.07 4.0e-07 4.4e-06 4.0e-07 3.3e-07
2 BLA alternative polyA XM_006228711.5 0.14 0.1 2.7e-05 0.07 0.07 0.07 0.08 9.5e-05 1.0e-04 9.8e-05 7.4e-05
3 BLA gene expression Zfp74 0.08 0.07 4.1e-03 0.03 0.03 0.03 0.03 1.5e-02 1.6e-02 1.5e-02 1.2e-02
4 PL isoform ratio NM_001271339.1 0.03 0.02 4.7e-04 0.02 0.03 0.03 0.02 4.3e-03 9.1e-04 5.5e-04 1.3e-03
5 PL alternative polyA NM_001271339.1 0.04 0.03 4.8e-07 0.06 0.06 0.05 0.05 9.5e-07 1.1e-06 3.5e-06 3.8e-06
6 pVTA gene expression Zfp74 0.23 0.24 4.2e-07 0.06 0.04 0.05 0.03 1.5e-05 5.1e-04 5.4e-05 1.3e-03
7 IC gene expression Zfp74 0.07 0.06 7.4e-03 0.01 0.02 -0 0.01 7.7e-02 3.3e-02 4.0e-01 1.5e-01
8 BLA isoform ratio XM_063269106.1 0.06 0.05 2.7e-03 0.05 0.04 0.04 0.04 1.3e-03 4.1e-03 2.8e-03 2.2e-03
9 PL alternative polyA XM_006228711.5 0.04 0.03 9.0e-07 0.05 0.05 0.05 0.04 7.9e-06 2.2e-06 7.2e-06 1.2e-05
10 Brain alternative polyA NM_001271339.1 0.08 0.07 1.2e-05 0.05 0.01 0.04 0.02 2.2e-05 2.7e-02 2.6e-04 3.9e-03
11 Brain alternative polyA XM_006228711.5 0.08 0.07 1.3e-05 0.05 0.01 0.04 0.02 2.3e-05 3.0e-02 3.0e-04 5.8e-03
12 Brain isoform ratio NM_001271339.1 0.03 0.03 5.1e-04 0.03 0.03 0.03 0.02 5.8e-04 1.7e-03 1.3e-03 2.5e-03
13 NAcc alternative polyA XM_006228711.5 0.02 0.02 1.8e-03 0.01 0.01 0.01 0.01 2.3e-03 4.6e-03 2.4e-03 2.8e-03
14 NAcc alternative polyA NM_001271339.1 0.03 0.03 1.5e-03 0.01 0.01 0.02 0.02 2.1e-03 6.5e-03 1.5e-03 1.1e-03
15 PL gene expression Zfp74 0.02 0.02 3.2e-03 0.01 0.02 0.02 0.01 9.4e-03 5.5e-03 6.6e-03 1.1e-02
16 RMTg alternative TSS XM_063269106.1 0.12 0.1 4.1e-03 0.1 0.05 0.03 0.06 1.5e-03 1.9e-02 5.7e-02 9.6e-03
17 BLA isoform ratio NM_001271339.1 0.22 0.18 1.9e-05 0.05 0.06 0.05 0.06 7.4e-04 2.6e-04 8.2e-04 3.3e-04
18 BLA alternative polyA NM_001271339.1 0.12 0.08 3.8e-05 0.06 0.07 0.06 0.06 5.7e-04 1.2e-04 2.4e-04 2.5e-04
19 NAcc gene expression Zfp74 0.08 0.04 0.0e+00 0.12 0.12 0.12 0.08 2.7e-17 5.9e-17 2.8e-17 1.1e-12
20 Adipose gene expression Zfp74 0.07 0.07 8.6e-06 0.03 0.03 0.03 0.03 1.1e-04 1.6e-04 1.1e-04 1.4e-04
21 Liver gene expression Zfp74 0.03 0.03 5.9e-03 0.01 0.01 0 0 4.0e-02 5.2e-02 2.1e-01 2.8e-01
22 RMTg gene expression Zfp74 0.29 0.16 1.9e-07 0.23 0.25 0.29 0.24 7.1e-07 3.2e-07 2.8e-08 4.3e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.40.72.00.21.20.0-0.4-0.70.70.61.40.7-1.01.0-0.90.6-0.60.90.7-0.9-1.00.51.21.20.9
Area under the delay curve0.81.02.01.30.91.4-1.1-1.41.41.10.81.0-0.70.7-0.71.2-1.20.80.8-0.9-0.71.10.30.30.4
BMI with tail0.10.30.7-0.6-0.3-0.70.70.4-0.4-0.5-0.4-0.60.6-0.60.6-0.30.3-0.5-0.50.40.5-0.4-0.4-0.4-0.9
BMI without tail0.41.22.51.40.91.3-0.9-1.51.51.10.81.1-0.80.8-0.81.6-1.61.00.9-1.1-0.91.50.70.60.6
Body weight2.812.315.43.33.93.3-3.4-3.33.33.53.93.5-3.63.6-3.63.3-3.33.63.4-3.5-3.63.23.93.83.3
Weight adjusted by age0.10.10.5-0.30.4-0.3-0.00.1-0.1-0.30.5-0.1-0.30.3-0.5-0.20.2-0.1-0.70.3-0.0-0.50.60.4-0.1
Bone surface1.22.13.61.01.70.9-1.1-1.31.31.41.91.4-1.61.6-1.61.1-1.11.61.6-1.7-1.71.21.81.81.0
Bone volume1.22.23.91.01.80.9-1.1-1.31.31.42.01.4-1.61.6-1.61.1-1.21.61.5-1.6-1.71.11.91.91.2
Breakpoint value in progressive ratio session1.82.24.61.81.02.0-1.6-1.11.11.70.71.6-1.01.0-1.11.8-1.81.52.1-1.6-1.31.71.01.01.5
Number of licking bursts3.04.96.9-2.1-1.7-2.22.12.2-2.2-2.3-2.1-2.32.3-2.32.3-2.32.3-2.3-2.42.32.3-2.3-1.9-1.8-2.6
Context. condit. distance diff. score0.00.00.5-0.00.20.10.2-0.00.0-0.0-0.2-0.10.2-0.20.0-0.10.1-0.1-0.10.00.10.10.20.2-0.7
Locomotion velocity, session 10.60.61.2-1.0-0.8-1.11.00.8-0.8-0.8-0.6-0.90.9-0.91.0-0.80.8-0.8-0.60.60.7-0.6-0.6-0.6-0.4
Locomotion distance, session 10.50.61.20.90.70.8-0.7-0.70.70.80.70.8-0.50.5-0.50.7-0.70.70.8-0.8-0.70.91.11.10.5
Locomotion velocity, session 20.50.61.4-0.7-1.1-0.51.00.5-0.5-0.7-1.2-0.70.8-0.80.8-0.40.4-0.7-0.60.70.8-0.6-1.1-1.1-0.6
Locomotion distance, session 21.52.03.6-1.4-1.6-1.61.51.3-1.3-1.4-1.5-1.41.5-1.51.5-1.21.2-1.4-1.21.31.4-1.3-1.3-1.3-1.9
Locomotion velocity, session 30.30.30.5-0.7-0.4-0.60.70.7-0.7-0.7-0.7-0.60.5-0.50.5-0.60.6-0.6-0.70.60.6-0.5-0.4-0.4-0.7
Locomotion distance, session 33.33.64.82.11.62.1-2.1-2.02.02.01.32.0-2.02.0-1.92.1-2.11.91.9-1.8-1.82.21.61.50.8
Stereotopy head waving bouts, day 30.70.81.8-1.3-0.7-1.11.21.2-1.2-0.9-0.6-0.90.7-0.70.7-1.21.2-0.8-0.70.80.7-1.0-0.9-0.90.0
Stereotopy head waving duration, day 31.61.93.3-1.8-1.1-1.61.81.6-1.6-1.4-0.9-1.41.2-1.21.2-1.71.7-1.3-1.21.31.2-1.4-1.4-1.4-0.4
Locomotion velocity, session 70.30.30.50.30.70.4-0.3-0.40.40.50.50.5-0.50.5-0.70.6-0.60.60.6-0.6-0.60.40.70.7-0.1
Locomotion distance, session 70.10.20.70.30.30.2-0.4-0.20.20.40.30.4-0.40.4-0.50.4-0.40.40.4-0.5-0.50.40.80.80.2
Stereotopy head waving bouts, day 71.71.92.3-1.2-1.3-1.11.31.3-1.3-1.4-1.2-1.41.5-1.51.5-1.41.4-1.5-1.51.51.5-1.3-1.3-1.3-1.5
Stereotopy head waving duration, day 72.22.63.3-1.4-1.4-1.41.61.5-1.5-1.6-1.5-1.71.8-1.81.7-1.71.7-1.7-1.71.71.8-1.6-1.7-1.7-1.5
Locomotion velocity, session 84.14.97.2-2.3-1.9-2.22.42.2-2.2-2.2-2.3-2.22.2-2.22.1-2.32.3-2.2-2.12.12.2-2.3-2.0-2.0-2.7
Locomotion distance, session 80.71.03.6-0.9-0.9-0.91.00.9-0.9-1.0-1.2-1.01.1-1.11.0-0.90.9-1.0-1.10.91.0-0.8-0.7-0.7-1.9
Degree of sensitization distance0.70.71.3-1.1-0.6-1.11.11.0-1.0-0.9-0.5-0.90.8-0.80.7-1.01.0-0.8-0.80.70.7-1.1-0.3-0.3-0.3
Degree of sensitization stereotypy1.21.32.3-0.8-1.0-0.70.91.0-1.0-1.1-1.0-1.11.3-1.31.2-1.11.2-1.3-1.31.31.3-1.1-1.1-1.1-1.5
Conditioned locomotion0.40.41.0-0.3-1.0-0.10.70.2-0.2-0.5-0.7-0.60.8-0.80.9-0.30.4-0.7-0.40.60.7-0.3-1.0-1.0-0.6
Cocaine response after cond. corrected0.10.10.40.2-0.50.3-0.1-0.10.1-0.0-0.4-0.00.1-0.10.20.2-0.2-0.1-0.20.20.20.0-0.3-0.40.7
Cocaine response after cond. not corrected0.00.00.60.2-0.40.1-0.1-0.20.20.0-0.30.0-0.10.1-0.00.2-0.2-0.0-0.00.00.00.1-0.1-0.20.8
Cocaine response before conditioning1.01.22.00.71.20.4-0.8-1.01.01.01.31.0-1.31.3-1.20.8-0.91.21.2-1.3-1.41.01.41.40.8
Saline control response0.10.10.30.2-0.60.20.1-0.10.1-0.1-0.5-0.10.4-0.40.50.1-0.0-0.2-0.10.20.3-0.2-0.3-0.30.2
Bone: connectivity density0.20.30.6-0.20.7-0.2-0.1-0.20.20.30.80.4-0.70.7-0.70.1-0.20.60.5-0.6-0.70.20.70.70.3
Bone: cortical apparent density1.82.54.1-1.7-1.6-2.01.71.5-1.5-1.7-1.5-1.71.6-1.61.6-1.71.7-1.6-1.61.51.5-1.5-1.2-1.1-1.8
Bone: cortical area1.62.53.21.71.61.7-1.6-1.81.81.61.51.6-1.61.6-1.61.4-1.41.61.4-1.6-1.61.51.61.51.5
Bone: cortical porosity1.31.53.2-1.6-0.8-1.41.21.5-1.5-1.2-0.8-1.10.8-0.80.7-1.41.4-1.0-1.01.10.9-1.5-1.2-1.2-1.8
Bone: cortical porosity2.02.24.6-1.7-1.2-1.61.51.6-1.6-1.4-1.1-1.41.1-1.11.1-1.71.7-1.3-1.31.31.2-1.7-1.5-1.5-2.1
Bone: cortical thickness0.61.01.51.11.11.2-1.1-1.21.21.00.91.0-1.01.0-1.00.8-0.81.00.8-1.0-0.91.01.01.01.2
Bone: cortical thickness0.60.71.1-0.9-0.9-0.70.90.8-0.8-0.8-0.8-0.91.0-1.00.9-1.01.0-0.9-0.80.90.9-0.8-0.8-0.8-0.6
Bone: cortical tissue density2.12.94.6-1.8-1.7-2.21.81.6-1.6-1.8-1.6-1.81.7-1.71.7-1.81.8-1.7-1.71.61.6-1.6-1.2-1.2-1.9
Condit. Reinf. active minus inactive responses0.20.20.4-0.4-0.3-0.60.60.3-0.3-0.5-0.4-0.50.5-0.50.4-0.10.1-0.4-0.30.40.4-0.3-0.6-0.7-0.4
Condit. Reinf. active-inactive response ratio0.10.10.8-0.3-0.0-0.30.40.2-0.2-0.3-0.2-0.30.3-0.30.2-0.00.0-0.3-0.30.40.3-0.2-0.8-0.90.2
Condit. Reinf. active responses2.02.53.4-1.5-1.6-1.71.71.4-1.4-1.6-1.6-1.61.8-1.81.7-1.31.3-1.6-1.41.51.6-1.3-1.7-1.7-1.8
Condit. Reinf. inactive responses2.32.85.3-1.4-2.0-1.71.61.5-1.5-1.6-1.9-1.72.0-2.01.9-1.51.5-1.7-1.41.51.7-1.4-1.5-1.4-2.3
Incentive salience index mean0.10.20.4-0.2-0.3-0.50.50.0-0.0-0.4-0.5-0.40.5-0.50.40.1-0.1-0.4-0.30.30.4-0.1-0.6-0.7-0.5
Condit. Reinf. lever presses0.00.10.20.2-0.0-0.10.0-0.40.40.1-0.30.00.0-0.00.10.4-0.40.10.1-0.1-0.10.4-0.3-0.3-0.4
Condit. Reinf. active minus inactive responses1.92.54.12.01.22.0-1.7-2.02.01.70.91.6-1.41.4-1.51.8-1.81.51.6-1.5-1.41.60.80.91.6
Condit. Reinf. active-inactive response ratio0.10.10.50.6-0.20.7-0.3-0.40.40.1-0.50.00.3-0.30.20.2-0.2-0.2-0.30.20.40.0-0.3-0.20.3
Condit. Reinf. active responses4.05.67.22.62.22.5-2.5-2.72.72.52.02.4-2.42.4-2.42.6-2.52.42.4-2.4-2.32.51.71.82.1
Condit. Reinf. inactive responses4.05.26.92.12.22.0-2.3-2.22.22.42.22.4-2.62.6-2.62.2-2.22.52.6-2.4-2.52.41.91.81.5
Condit. Reinf. lever presses8.712.014.23.83.63.7-3.7-3.73.73.63.23.6-3.33.3-3.43.5-3.53.53.5-3.4-3.43.42.92.83.4
Condit. Reinf. lever reinforcers received4.36.17.62.72.42.7-2.6-2.82.82.62.12.5-2.42.4-2.52.6-2.62.52.5-2.4-2.42.51.92.02.1
Conditioned reinforcement - actives0.61.01.4-1.0-1.1-0.61.11.0-1.0-0.9-1.0-1.01.1-1.11.0-1.21.2-1.0-0.91.01.1-1.0-0.8-0.8-0.5
Conditioned reinforcement - inactives0.10.20.70.50.20.9-0.4-0.50.50.50.20.5-0.20.2-0.20.3-0.30.40.7-0.4-0.30.4-0.1-0.1-0.3
Conditioned locomotion2.63.35.0-2.1-1.9-2.02.21.7-1.7-1.8-1.8-1.91.9-1.91.9-1.91.9-1.8-1.21.61.7-1.8-1.8-1.8-1.7
Patch foraging indifference point 0 sec0.10.20.50.20.20.4-0.6-0.20.20.40.00.4-0.70.7-0.70.2-0.20.50.4-0.4-0.50.3-0.1-0.10.1
Patch foraging indifference point AUC0.71.01.4-1.1-0.8-0.91.01.1-1.1-1.0-0.8-1.01.0-1.00.9-1.21.2-1.0-0.81.01.0-1.1-1.1-1.1-0.8
Delay disc. indifference point, 0s delay0.50.61.61.30.11.3-0.6-1.31.30.90.30.70.3-0.30.11.0-1.00.50.7-0.8-0.31.00.50.5-0.0
Delay disc. indifference point, 16s delay1.82.04.82.01.02.2-1.6-2.02.01.60.91.4-1.11.1-1.01.8-1.81.21.2-1.3-1.01.60.20.20.7
Delay disc. indifference point, 2s delay1.01.22.41.30.91.6-1.2-1.31.31.21.11.2-0.80.8-0.80.9-0.91.01.0-1.1-0.91.01.11.10.7
Delay disc. indifference point, 24s delay2.32.63.31.81.61.7-1.8-1.71.71.71.31.7-1.71.7-1.71.8-1.81.61.2-1.6-1.61.81.11.11.0
Delay disc. indifference point, 4s delay0.10.10.40.60.30.6-0.4-0.60.60.30.10.2-0.00.0-0.00.4-0.40.1-0.0-0.00.10.3-0.3-0.3-0.1
Delay disc. indifference point, 8s delay0.20.20.80.20.90.2-0.4-0.20.20.40.70.4-0.60.6-0.70.5-0.50.40.3-0.4-0.40.50.20.20.0
Indifference point function ln k0.30.61.00.90.40.7-0.8-1.01.00.80.40.8-0.50.5-0.61.0-1.00.70.6-0.8-0.71.00.60.60.7
Indifference point function log k0.30.61.00.90.40.7-0.8-1.01.00.80.40.8-0.50.5-0.61.0-1.00.70.6-0.8-0.71.00.60.60.7
Patch foraging total patch changes 0 sec0.10.20.60.40.30.5-0.7-0.40.40.50.10.6-0.80.8-0.80.4-0.40.60.5-0.5-0.60.50.10.10.2
Patch foraging total patch changes 12 sec0.00.10.40.1-0.10.2-0.1-0.10.10.2-0.10.1-0.20.2-0.10.2-0.20.10.1-0.1-0.10.2-0.6-0.60.3
Patch foraging total patch changes 18 sec0.20.41.0-1.0-0.2-0.70.61.0-1.0-0.6-0.2-0.50.1-0.10.1-0.90.8-0.4-0.60.50.3-0.8-0.2-0.2-0.7
Patch foraging total patch changes 24 sec0.40.71.10.81.00.9-0.9-0.60.60.81.00.8-0.90.9-0.90.6-0.60.70.7-0.7-0.70.71.11.00.2
Patch foraging total patch changes 6 sec0.00.10.2-0.3-0.10.0-0.10.5-0.5-0.1-0.30.0-0.40.4-0.3-0.30.30.10.10.1-0.1-0.3-0.3-0.30.1
Patch foraging time to switch 0 sec0.30.61.4-0.6-1.0-0.60.90.4-0.4-0.7-1.0-0.80.8-0.81.0-0.20.2-0.8-0.90.70.8-0.2-1.1-1.2-0.5
Patch foraging water rate 0 sec0.61.22.3-1.3-0.9-1.11.01.3-1.3-1.1-0.9-1.00.9-0.90.8-1.51.5-1.0-0.81.10.9-1.5-1.0-0.9-1.2
Patch foraging water rate 12 sec0.40.81.90.91.31.0-1.1-0.80.80.71.40.8-0.90.9-1.00.3-0.30.70.7-0.4-0.60.41.21.20.6
Patch foraging water rate 18 sec0.10.20.8-0.3-0.1-0.20.10.6-0.6-0.40.1-0.30.3-0.30.2-0.80.8-0.4-0.30.50.4-0.9-0.4-0.4-0.3
Patch foraging water rate 24 sec0.10.10.60.2-0.00.3-0.10.0-0.00.00.20.00.1-0.10.1-0.40.4-0.1-0.10.20.2-0.60.10.2-0.8
Patch foraging water rate 6 sec0.60.92.00.81.30.7-1.0-0.80.80.81.40.9-1.21.2-1.30.4-0.51.00.9-0.8-1.00.41.21.30.2
Seeking ratio, delayed vs. immediate footshock1.31.62.51.41.31.5-1.3-1.61.61.31.31.3-1.21.2-1.31.4-1.41.20.9-1.2-1.11.21.41.40.2
Distance traveled before self-admin0.40.62.21.3-0.11.5-0.7-0.90.91.00.00.80.1-0.10.10.8-0.80.60.6-0.9-0.40.90.10.00.6
Distance traveled after self-admin2.12.53.41.51.71.7-1.7-1.11.11.71.91.7-1.71.7-1.61.4-1.41.71.5-1.7-1.71.51.61.61.5
Extensor digitorum longus weight0.20.71.0-0.8-0.7-0.81.00.6-0.6-0.9-0.5-0.90.9-0.91.0-0.90.9-0.9-1.00.90.9-1.0-0.5-0.5-0.3
Bone: elastic displacement0.00.00.1-0.1-0.00.0-0.10.2-0.20.00.20.0-0.10.1-0.1-0.30.30.0-0.00.0-0.0-0.10.00.00.4
Bone: elastic work1.92.53.31.51.61.6-1.5-1.51.51.61.81.6-1.61.6-1.51.4-1.41.61.5-1.6-1.61.51.61.51.7
Bone: endosteal estimation1.53.34.11.81.81.7-1.9-1.81.81.91.91.9-1.91.9-1.91.7-1.72.02.0-2.0-2.01.71.71.71.6
Bone: endosteal perimeter1.43.04.02.01.51.9-1.8-2.02.01.91.51.8-1.61.6-1.61.9-1.91.81.9-1.8-1.71.91.41.41.3
Epididymis fat weight0.00.10.5-0.40.2-0.70.30.3-0.3-0.30.5-0.30.0-0.00.2-0.40.3-0.2-0.50.10.1-0.40.40.4-0.1
Delta time in closed arm before/after self-admin0.90.81.80.71.30.6-0.9-1.01.00.81.30.9-1.11.1-1.20.6-0.61.00.8-0.9-1.00.70.90.90.6
Delta time in open arm before/after self-admin0.50.51.7-0.5-1.0-0.50.40.8-0.8-0.8-1.1-0.70.4-0.40.4-0.60.6-0.8-1.31.00.8-0.8-0.5-0.5-0.1
Diff in mean of infusions in LGA sessions0.30.41.2-0.1-1.10.20.30.6-0.6-0.1-1.1-0.30.9-0.90.90.0-0.0-0.40.30.30.60.0-1.0-1.0-0.5
Delay discount exponential model param0.91.01.9-1.3-1.0-1.41.21.4-1.4-1.1-0.9-1.01.0-1.00.9-1.21.1-0.9-0.80.90.8-1.1-0.3-0.3-0.5
Extinction: sum of active levers before priming3.84.15.81.62.11.2-1.7-1.71.71.92.01.9-1.91.9-1.92.4-2.42.12.4-2.2-2.22.32.22.22.4
Active lever presses in extinction session 61.71.74.91.11.11.1-1.0-1.01.01.41.01.3-1.01.0-1.01.4-1.51.41.8-1.6-1.41.41.11.12.2
Bone: final force1.82.84.01.52.01.4-1.6-1.61.61.71.91.7-1.81.8-1.81.5-1.51.71.6-1.8-1.81.51.81.71.5
Bone: final moment2.43.84.81.82.21.7-1.9-1.91.91.92.12.0-2.12.1-2.11.8-1.82.01.9-2.0-2.11.82.12.01.8
Food consumed during 24 hour testing period0.60.81.30.91.20.9-0.9-0.90.90.91.00.9-1.01.0-1.00.8-0.81.01.0-1.0-1.00.80.60.60.1
Glucose0.30.40.7-0.6-0.3-0.70.50.8-0.8-0.6-0.2-0.60.7-0.70.7-0.80.8-0.7-0.80.70.7-0.8-0.4-0.30.0
Heart weight0.10.10.80.50.40.9-0.3-0.50.50.40.50.4-0.30.3-0.30.4-0.40.30.2-0.1-0.20.30.0-0.00.2
Delay discount hyperbolic model param0.70.81.6-1.2-0.9-1.31.11.2-1.2-0.9-0.8-0.90.8-0.80.7-1.01.0-0.8-0.70.70.6-0.9-0.3-0.3-0.4
Intermittent access intake day 1-15 change0.91.83.90.91.61.3-1.2-0.90.91.21.51.3-1.61.6-1.61.1-1.11.41.1-1.2-1.40.92.02.01.0
Intermittent access intake escalation0.61.23.30.61.30.9-1.0-0.60.60.91.21.0-1.41.4-1.40.8-0.81.10.8-1.0-1.20.61.81.80.9
Intermittent access intake escalation 21.31.52.01.21.41.4-1.3-1.01.01.31.21.3-1.31.3-1.41.2-1.21.21.0-1.2-1.21.11.21.21.2
Intermitt. access day 1 inactive lever presses1.86.89.62.82.52.2-2.7-3.13.12.72.32.6-2.72.7-2.63.0-3.02.72.6-2.7-2.73.01.71.71.6
Intermitt. access day 15 inactive lever presses0.71.32.21.41.21.0-1.5-1.31.31.21.11.2-1.31.3-1.21.4-1.41.20.7-1.1-1.21.30.60.60.0
Intermitt. access escalation Index0.10.10.30.2-0.60.2-0.1-0.00.0-0.1-0.4-0.20.5-0.50.6-0.20.2-0.3-0.40.30.4-0.3-0.2-0.2-0.6
Intermittent access day 1 total infusions1.52.44.0-1.2-1.8-1.01.51.4-1.4-1.4-1.8-1.52.0-2.01.9-1.31.3-1.6-1.51.41.7-1.2-1.3-1.3-1.9
Intermittent access day 15 total infusions0.10.10.3-0.2-0.40.30.20.4-0.4-0.1-0.4-0.20.4-0.40.3-0.10.1-0.3-0.50.10.3-0.20.30.3-0.5
Intermittent access terminal intake (last 3 days)0.20.30.6-0.1-0.70.50.20.6-0.6-0.1-0.7-0.30.7-0.70.7-0.10.2-0.5-0.60.40.6-0.2-0.3-0.3-0.8
Intermittent access total infusions0.60.71.2-0.7-1.0-0.20.81.0-1.0-0.6-0.9-0.71.1-1.11.0-0.60.6-0.8-0.90.70.9-0.6-0.5-0.5-1.1
Intermittent access day 1 locomotion0.70.92.4-0.6-1.3-0.50.90.6-0.6-0.7-1.3-0.81.3-1.31.2-0.60.6-0.9-0.60.71.0-0.5-1.1-1.1-1.6
Intermittent access day 15 total locomotion0.10.10.6-0.6-0.3-0.20.50.6-0.6-0.1-0.4-0.20.3-0.30.2-0.20.2-0.10.3-0.00.0-0.20.10.1-0.8
Intermittent access total locomotion1.11.32.3-1.2-1.4-1.01.31.2-1.2-1.0-1.4-1.11.4-1.41.3-1.01.0-1.1-0.60.91.1-0.9-1.1-1.1-1.5
Intermittent access standard deviation2.34.85.42.22.22.3-2.2-2.12.12.32.12.3-2.22.2-2.22.2-2.22.32.2-2.3-2.22.22.22.21.6
Left kidney weight1.88.212.72.33.32.3-2.8-2.52.52.63.52.7-3.33.3-3.22.4-2.52.82.6-2.7-3.02.33.63.52.9
Right kidney weight2.411.014.92.93.62.8-3.2-3.13.13.13.83.2-3.43.4-3.33.1-3.13.33.1-3.3-3.43.03.93.83.6
Cocaine induced anxiety0.00.00.00.0-0.00.1-0.00.2-0.20.10.10.10.0-0.00.10.2-0.20.00.1-0.0-0.00.1-0.0-0.00.2
Post-drug Anxiety0.10.10.40.5-0.10.5-0.3-0.30.30.3-0.00.20.1-0.10.10.3-0.20.10.2-0.10.10.3-0.6-0.60.1
Baseline Anxiety0.10.10.50.50.40.3-0.4-0.70.70.20.20.2-0.30.3-0.40.1-0.10.20.1-0.1-0.10.2-0.3-0.3-0.3
Tail length5.220.322.64.74.64.8-4.6-4.54.54.64.64.6-4.54.5-4.54.5-4.54.54.3-4.4-4.44.34.44.54.4
Length with tail7.030.334.15.55.85.7-5.8-5.25.25.65.85.7-5.75.7-5.75.1-5.25.65.4-5.4-5.55.05.55.65.5
Length without tail2.78.812.52.73.42.8-3.2-2.52.52.93.53.0-3.23.2-3.32.4-2.43.02.9-2.8-3.12.33.43.43.0
Times rat made contact with spout1.01.12.1-1.4-0.1-1.31.21.4-1.4-1.1-0.7-1.10.9-0.91.0-1.51.4-1.0-1.11.00.9-1.2-0.3-0.3-0.6
Lifetime Intake0.81.01.5-1.0-1.2-0.61.01.2-1.2-0.9-1.1-0.91.2-1.21.1-0.90.9-1.0-1.20.91.1-0.8-0.6-0.6-1.1
Liver weight, left0.50.81.1-0.7-0.8-0.60.60.9-0.9-0.9-0.8-0.90.9-0.90.9-0.90.9-1.0-1.01.01.0-0.9-0.9-0.8-0.6
Liver weight, right0.20.40.9-0.3-0.8-0.10.40.6-0.6-0.5-0.8-0.50.7-0.70.8-0.60.6-0.7-0.70.70.8-0.6-0.9-0.90.1
Locomotor activity0.50.81.6-1.2-0.8-1.21.01.1-1.1-0.9-0.7-0.90.7-0.70.7-1.01.0-0.8-0.70.80.7-1.1-0.8-0.90.0
Locomotor testing distance0.71.32.5-1.5-1.1-1.61.41.4-1.4-1.2-0.8-1.21.0-1.01.0-1.21.2-1.1-1.11.00.9-1.2-0.7-0.8-0.5
Locomotor testing rearing1.83.65.4-2.0-1.9-1.82.02.0-2.0-2.1-1.6-2.01.8-1.81.8-2.12.1-2.0-2.32.02.0-2.1-1.1-1.1-1.6
Locomotion in novel chamber0.20.21.0-0.2-0.6-0.30.5-0.30.3-0.0-0.7-0.20.4-0.40.50.3-0.3-0.10.3-0.10.10.2-1.0-0.9-0.0
Locomotion in novel chamber post-restriction0.30.51.31.0-0.11.1-0.4-1.01.00.8-0.10.50.1-0.10.31.1-1.10.40.5-0.7-0.21.1-0.5-0.50.4
Fecal boli incidents, locomotor time 11.92.75.1-1.4-1.9-1.41.61.6-1.6-1.4-2.2-1.51.9-1.91.9-1.31.3-1.5-1.11.41.6-1.3-2.3-2.3-1.1
Change in fecal boli incidents, locomotor task0.00.00.3-0.00.2-0.1-0.0-0.30.3-0.00.40.0-0.30.3-0.20.1-0.10.10.10.0-0.10.1-0.2-0.20.5
Time >=10cm from walls, locomotor time 10.00.00.00.00.10.1-0.1-0.00.0-0.10.1-0.10.0-0.0-0.10.1-0.1-0.1-0.00.10.10.1-0.2-0.20.0
Bouts of movement, locomotor time 11.01.24.11.70.82.0-1.3-1.01.01.40.61.2-0.60.6-0.81.1-1.11.01.2-1.1-0.71.10.80.80.7
Total resting periods, locomotor time 11.01.13.91.70.72.0-1.2-1.11.11.40.51.2-0.50.5-0.61.2-1.21.01.3-1.1-0.71.20.60.60.8
Rest time, locomotor task time 10.91.23.5-0.3-1.3-0.40.90.5-0.5-0.7-1.5-0.91.6-1.61.5-0.60.6-1.0-0.20.91.2-0.6-1.9-1.9-0.6
Distance moved, locomotor task time 10.10.10.3-0.5-0.1-0.30.20.3-0.3-0.30.2-0.2-0.10.10.0-0.30.3-0.1-0.50.20.0-0.30.50.5-0.4
Vertical activity count, locomotor time 10.71.62.80.81.40.8-1.2-1.11.11.01.61.2-1.71.7-1.51.1-1.11.30.7-1.1-1.41.01.61.60.6
Time >=10cm from walls, locomotor time 20.71.12.6-0.3-1.2-0.10.70.4-0.4-0.8-1.5-0.91.4-1.41.3-0.70.8-1.1-0.81.01.2-0.8-1.6-1.6-0.8
Bouts of movement, locomotor time 20.10.10.90.50.10.9-0.1-0.40.40.30.30.20.1-0.10.00.1-0.10.00.2-0.10.10.10.10.10.4
Total resting periods, locomotor time 20.00.00.40.3-0.00.70.0-0.20.20.10.10.00.2-0.20.2-0.00.0-0.10.10.10.2-0.0-0.1-0.10.3
Rest time, locomotor task time 20.20.30.9-0.0-0.4-0.10.20.5-0.5-0.3-0.8-0.40.6-0.60.6-0.30.3-0.4-0.20.50.6-0.3-1.0-1.0-0.1
Distance moved, locomotor task time 20.30.30.8-0.7-0.4-0.50.60.3-0.3-0.6-0.1-0.50.3-0.30.4-0.80.8-0.5-0.90.50.4-0.80.10.1-0.8
Vertical activity count, locomotor time 20.50.71.20.80.90.8-0.8-1.11.10.71.00.8-0.90.9-0.90.7-0.70.80.6-0.7-0.80.70.90.90.3
Light reinforcement 10.10.30.6-0.5-0.4-0.50.40.6-0.6-0.6-0.5-0.50.2-0.20.2-0.70.7-0.5-0.40.70.5-0.7-0.4-0.4-0.6
Light reinforcement 22.53.84.8-2.2-1.8-2.22.12.0-2.0-2.0-1.9-2.01.7-1.71.6-2.12.1-1.9-1.81.91.8-2.1-2.1-2.1-1.8
Bone: marrow area1.63.54.31.91.81.7-1.9-1.81.82.01.92.0-1.91.9-1.91.7-1.72.02.1-2.0-2.01.71.71.71.7
Bone: maximum diameter1.42.63.21.61.61.7-1.6-1.81.81.71.61.7-1.71.7-1.61.5-1.51.61.6-1.6-1.61.51.51.51.4
Bone: maximum force2.95.26.42.22.52.1-2.3-2.22.22.32.52.3-2.32.3-2.32.1-2.22.32.1-2.3-2.32.12.32.32.1
Bone: maximum moment3.56.27.02.52.72.4-2.6-2.52.52.52.62.6-2.52.5-2.52.4-2.42.52.4-2.5-2.52.32.62.52.2
Mean time between licks in bursts0.00.10.20.4-0.30.3-0.3-0.50.50.20.20.2-0.40.4-0.30.3-0.30.20.1-0.1-0.20.30.00.0-0.3
Mean num. licks in bursts1.11.73.61.01.51.1-1.0-1.11.11.31.31.3-1.31.3-1.31.1-1.11.31.3-1.4-1.41.21.41.41.9
Cd content in liver0.30.30.9-0.6-0.1-0.70.50.6-0.6-0.6-0.1-0.50.4-0.40.4-0.90.9-0.5-0.30.50.4-1.0-0.2-0.2-0.5
Co content in liver0.40.51.0-0.8-0.7-1.00.90.5-0.5-0.8-0.8-0.80.6-0.60.6-0.60.6-0.7-0.70.70.6-0.6-0.8-0.8-0.5
Cu content in liver0.91.11.61.01.11.1-1.2-0.70.71.11.11.1-1.11.1-1.10.6-0.71.11.1-1.1-1.10.61.31.31.1
Fe content in liver0.30.30.8-0.4-0.6-0.70.50.3-0.3-0.6-0.7-0.60.6-0.60.6-0.40.4-0.6-0.50.50.6-0.4-0.9-0.9-0.4
K content in liver0.20.20.40.50.00.5-0.5-0.60.60.30.10.4-0.40.4-0.50.5-0.50.30.3-0.2-0.30.5-0.2-0.20.3
Mg content in liver0.30.31.2-0.4-0.7-0.20.40.4-0.4-0.5-0.8-0.50.4-0.40.3-0.50.5-0.5-0.50.70.6-0.5-1.1-1.10.0
Mn content in liver0.50.61.1-0.9-0.8-0.70.70.9-0.9-0.7-0.9-0.70.6-0.60.6-0.80.8-0.7-0.50.70.7-0.8-1.1-1.1-0.0
Na content in liver1.11.22.11.30.81.2-1.2-1.51.51.00.91.1-1.01.0-1.11.2-1.21.00.8-0.9-0.91.20.90.90.8
Rb content in liver0.10.10.2-0.2-0.4-0.10.20.2-0.2-0.2-0.3-0.20.3-0.30.2-0.10.1-0.3-0.10.30.3-0.1-0.4-0.5-0.4
Se content in liver5.56.58.1-2.6-2.4-2.72.52.6-2.6-2.6-2.7-2.62.4-2.42.4-2.52.5-2.5-2.62.62.5-2.6-2.9-2.8-1.8
Sr content in liver0.20.20.4-0.5-0.4-0.60.50.4-0.4-0.5-0.4-0.50.4-0.40.4-0.40.4-0.4-0.40.40.4-0.4-0.6-0.6-0.2
Zn content in liver2.83.14.3-2.0-1.5-2.11.81.9-1.9-1.9-1.5-1.81.4-1.41.4-2.02.0-1.7-1.71.81.6-2.0-1.8-1.8-1.3
Bone: minimum diameter3.87.09.73.02.33.0-2.8-3.13.12.82.32.8-2.52.5-2.52.8-2.82.62.6-2.6-2.52.62.32.31.9
Time in familiar zone, hab. session 10.40.31.30.50.70.5-0.5-0.40.40.50.60.5-0.50.5-0.40.4-0.40.50.5-0.5-0.50.50.80.81.1
Time in novel zone, hab. session 11.11.12.4-0.8-1.0-0.60.81.0-1.0-1.0-1.0-1.00.9-0.90.9-1.01.0-1.1-1.11.21.2-1.0-1.5-1.5-1.4
Total zone transitions, hab. session 10.00.10.20.4-0.20.2-0.1-0.20.20.1-0.10.00.4-0.40.40.4-0.4-0.10.1-0.00.20.30.00.0-0.4
Total locomotion distance, hab. session 11.62.23.92.01.01.9-1.7-1.61.61.71.21.6-1.21.2-1.11.8-1.81.41.6-1.5-1.31.81.00.91.4
Locomotion velocity, hab. session 11.01.42.21.50.71.3-1.2-1.31.31.30.91.2-0.90.9-0.81.4-1.41.11.3-1.2-1.01.40.80.71.2
Time in familiar zone, hab. session 22.22.34.11.51.31.6-1.5-1.51.51.61.11.6-1.61.6-1.61.5-1.51.61.8-1.6-1.61.60.80.82.0
Time in novel zone, hab. session 21.41.42.1-1.2-0.9-1.21.11.3-1.3-1.3-0.9-1.31.3-1.31.2-1.31.3-1.3-1.41.21.3-1.2-0.8-0.7-1.4
Total zone transitions, hab. session 22.73.54.6-1.4-2.2-1.51.81.6-1.6-1.8-2.0-1.92.1-2.12.1-1.51.5-2.0-1.92.02.1-1.7-2.0-2.0-2.0
Total locomotion distance, hab. session 20.10.10.40.1-0.40.20.10.0-0.0-0.1-0.2-0.10.3-0.30.4-0.00.0-0.2-0.10.20.3-0.1-0.6-0.6-0.4
Locomotion velocity, hab. session 20.10.20.5-0.1-0.5-0.10.30.2-0.2-0.3-0.4-0.30.4-0.40.6-0.20.2-0.4-0.20.40.4-0.3-0.6-0.7-0.5
Novel to familiar place preference ratio0.20.20.50.70.30.6-0.7-0.40.40.40.50.5-0.60.6-0.50.3-0.30.40.2-0.2-0.30.10.20.20.2
Novelty place preference0.10.10.40.50.20.5-0.6-0.20.20.30.30.3-0.40.4-0.30.2-0.20.20.0-0.1-0.2-0.00.10.2-0.0
Time in novel zone, NPP test0.00.00.10.3-0.00.3-0.4-0.00.00.10.10.1-0.20.2-0.1-0.00.0-0.0-0.20.10.1-0.2-0.10.0-0.2
Total zone transitions, NPP test0.10.10.3-0.4-0.4-0.50.40.4-0.4-0.3-0.3-0.40.5-0.50.5-0.40.4-0.3-0.10.20.3-0.30.00.0-0.3
Total locomotion distance, NPP test2.53.54.41.91.81.9-1.9-1.71.72.01.91.9-1.81.8-1.61.8-1.81.92.1-2.0-1.91.81.81.82.0
Locomotion velocity, NPP test2.83.95.02.01.92.1-2.0-1.91.92.12.02.1-1.91.9-1.71.9-2.02.12.2-2.1-2.02.01.81.82.2
Intraocular pressure0.00.00.10.3-0.30.1-0.1-0.10.10.1-0.3-0.00.1-0.10.20.0-0.0-0.00.1-0.00.10.0-0.1-0.1-0.3
Delta distance traveled before/after self-admin1.61.63.70.41.80.5-1.1-0.60.60.91.91.1-1.81.8-1.80.9-0.91.30.8-1.0-1.51.01.71.71.1
Delta ambulatory time before/after self-admin1.31.53.70.21.80.4-1.0-0.30.30.81.91.1-1.81.8-1.80.6-0.61.31.0-1.0-1.50.71.81.81.0
Parametrial fat weight0.20.41.0-1.0-0.2-0.90.60.8-0.8-0.8-0.2-0.70.2-0.20.2-0.90.9-0.6-0.90.80.5-0.8-0.6-0.60.4
Pavlov. Cond. lever latency0.10.10.40.20.30.2-0.2-0.10.10.20.60.2-0.20.2-0.30.1-0.10.20.1-0.2-0.20.10.50.50.4
Pavlov. Cond. magazine entry latency0.60.81.0-0.8-0.8-0.60.71.0-1.0-0.8-0.9-0.91.0-1.01.0-1.01.0-1.0-1.01.01.0-1.0-0.9-1.0-0.4
Pavlov. Cond. change in total contacts0.30.30.9-0.2-0.6-0.30.30.2-0.2-0.5-0.8-0.50.6-0.60.7-0.10.1-0.6-0.50.60.6-0.2-0.8-0.8-0.9
Pavlov. Cond. index score0.40.60.9-0.6-0.7-0.60.70.7-0.7-0.7-0.9-0.70.8-0.80.8-0.70.7-0.8-0.80.80.8-0.7-0.9-0.9-0.6
Pavlov. Cond. latency score0.20.20.6-0.4-0.6-0.40.50.3-0.3-0.5-0.8-0.50.5-0.50.6-0.40.4-0.5-0.50.50.5-0.3-0.7-0.7-0.5
Pavlov. Cond. lever contacts0.10.10.20.40.00.4-0.3-0.40.40.3-0.40.2-0.20.2-0.10.4-0.40.20.2-0.2-0.20.3-0.2-0.20.0
Pavlov. Cond. magazine entry number0.50.60.80.60.60.5-0.6-0.80.80.70.70.7-0.90.9-0.90.8-0.80.80.9-0.9-0.90.80.80.80.5
Pavlov. Cond. intertrial magazine entries0.70.81.5-0.6-1.1-0.91.00.4-0.4-0.9-1.2-1.01.1-1.11.0-0.40.5-1.0-0.70.91.0-0.5-1.0-1.0-0.9
Pavlov. Cond. lever-magazine prob. diff.0.70.91.3-0.8-0.8-0.70.80.9-0.9-0.9-1.0-0.90.9-0.91.0-0.90.9-1.0-1.01.01.0-0.9-1.1-1.1-0.7
Pavlov. Cond. response bias0.30.30.6-0.4-0.4-0.30.40.5-0.5-0.5-0.6-0.50.6-0.60.6-0.50.5-0.6-0.60.60.6-0.6-0.7-0.7-0.1
Pavlov. Cond. lever latency5.57.49.7-2.8-3.1-2.72.92.8-2.8-2.8-2.9-2.82.8-2.82.9-2.72.7-2.8-2.62.72.7-2.6-2.4-2.4-2.3
Pavlov. Cond. magazine entry latency4.04.85.62.32.32.2-2.2-2.32.32.22.12.2-2.22.2-2.22.4-2.42.22.3-2.2-2.22.21.71.72.0
Pavlov. Cond. change in total contacts7.812.614.23.73.73.7-3.7-3.83.83.63.63.6-3.53.5-3.63.7-3.73.53.3-3.5-3.53.53.33.32.8
Pavlov. Cond. index score6.48.611.03.03.32.9-3.0-3.13.13.03.13.0-2.92.9-3.03.0-3.02.92.8-2.9-2.92.82.62.62.5
Pavlov. Cond. latency score5.77.69.72.83.12.7-2.8-2.92.92.82.92.8-2.82.8-2.92.8-2.82.82.7-2.7-2.72.62.32.32.3
Pavlov. Cond. lever contacts5.98.210.63.03.32.9-3.0-3.03.02.93.02.9-2.82.8-2.92.9-2.92.82.7-2.8-2.82.82.62.62.4
Pavlov. Cond. magazine entry number4.55.67.4-2.4-2.7-2.22.42.5-2.5-2.3-2.6-2.32.3-2.32.3-2.42.4-2.3-2.22.32.3-2.2-2.3-2.4-2.2
Pavlov. Cond. intertrial magazine entries1.52.33.6-1.9-1.4-1.91.51.9-1.9-1.5-1.4-1.51.2-1.21.2-1.91.8-1.3-1.31.31.2-1.7-1.0-1.0-1.7
Pavlov. Cond. lever-magazine prob. diff.6.08.010.32.93.22.8-2.9-2.92.92.93.02.9-2.82.8-2.92.8-2.82.82.7-2.8-2.82.62.52.52.5
Pavlov. Cond. response bias7.09.512.03.23.53.1-3.2-3.23.23.13.33.1-3.03.0-3.13.1-3.13.12.9-3.0-3.03.02.92.92.5
Time in closed arm before self-admin1.21.52.5-0.6-1.4-0.30.91.0-1.0-1.1-1.2-1.21.6-1.61.5-1.21.2-1.4-1.61.31.6-1.0-1.2-1.1-1.3
Time in closed arm after self-admin0.50.62.11.20.21.3-0.6-1.41.40.90.50.70.0-0.0-0.10.8-0.80.50.7-0.7-0.31.0-0.2-0.30.0
Time in open arm before self-admin3.94.27.01.32.61.0-1.8-1.61.61.92.32.0-2.52.5-2.41.9-1.92.32.4-2.3-2.51.91.91.91.8
Time in open arm after self-admin0.60.61.80.10.90.0-0.70.2-0.20.40.70.6-1.41.4-1.30.5-0.60.80.3-0.5-0.90.41.11.11.1
Bone: periosteal estimation2.34.85.32.32.22.2-2.3-2.32.32.32.22.3-2.22.2-2.21.9-1.92.32.2-2.3-2.32.02.12.12.0
Bone: periosteal perimeter1.83.15.02.11.42.1-1.8-2.22.21.91.31.8-1.51.5-1.52.0-1.91.71.8-1.8-1.61.91.31.31.7
Bone: post-yield work2.03.03.51.81.71.7-1.8-1.81.81.91.71.8-1.81.8-1.81.7-1.71.81.9-1.9-1.81.61.61.61.0
Progressive ratio test 1 active lever presses0.00.00.2-0.2-0.10.10.20.3-0.30.1-0.1-0.00.3-0.30.20.1-0.1-0.00.1-0.20.00.30.20.2-0.5
Progressive ratio test 1 breakpoint0.00.00.2-0.0-0.00.20.10.1-0.10.2-0.00.10.2-0.20.10.2-0.20.10.2-0.3-0.10.50.20.2-0.4
Progressive ratio test 1 inactive lever presses0.20.30.60.80.10.8-0.6-0.70.70.6-0.00.6-0.20.2-0.20.5-0.50.50.5-0.6-0.40.70.10.1-0.5
Progressive ratio test 2 active lever presses0.30.30.8-0.5-0.8-0.30.70.7-0.7-0.4-0.7-0.50.9-0.90.8-0.40.4-0.6-0.50.30.6-0.2-0.1-0.1-0.6
Progressive ratio test 2 breakpoint0.40.51.1-0.6-0.9-0.40.80.8-0.8-0.5-0.8-0.71.0-1.00.9-0.50.5-0.7-0.70.40.7-0.3-0.2-0.2-0.7
Progressive ratio test 2 inactive lever presses0.50.92.01.40.31.4-0.8-1.11.11.10.10.9-0.20.2-0.21.4-1.30.81.2-1.1-0.71.40.30.30.0
Incentive Sensitization - Responses0.50.71.4-0.5-1.1-0.60.80.7-0.7-0.7-1.1-0.81.2-1.21.1-0.60.6-0.9-1.00.60.9-0.5-0.4-0.4-0.8
Incentive Sensitization - Breakpoint0.50.71.3-0.6-1.1-0.60.80.7-0.7-0.7-1.0-0.81.1-1.11.1-0.60.7-0.9-1.00.70.9-0.6-0.4-0.4-0.8
Sum of active levers in priming session hrs 5-60.10.10.6-0.5-0.4-0.50.50.8-0.8-0.2-0.3-0.30.4-0.40.40.0-0.0-0.20.30.00.10.0-0.1-0.1-0.2
Progressive ratio0.00.00.20.1-0.1-0.10.0-0.30.30.1-0.20.10.1-0.10.00.2-0.20.1-0.0-0.2-0.10.2-0.4-0.4-0.2
Food seeking constrained by brief footshock2.93.54.92.01.91.9-2.0-1.51.52.11.62.0-1.91.9-1.91.9-2.02.02.2-2.1-2.02.11.41.41.6
Seeking ratio, punishment vs. effort0.40.61.21.00.91.1-1.0-0.60.60.90.90.9-0.80.8-0.80.7-0.70.80.9-0.7-0.70.70.80.80.6
Retroperitoneal fat weight0.62.53.9-1.8-1.2-1.91.51.8-1.8-1.7-1.0-1.61.3-1.31.4-1.91.9-1.5-1.71.71.4-2.0-1.4-1.40.1
Reaction time number correct0.10.10.4-0.70.1-0.50.50.5-0.5-0.50.1-0.40.2-0.20.1-0.60.6-0.3-0.30.40.2-0.50.20.2-0.1
Reaction time mean minus median0.10.40.90.20.70.3-0.60.1-0.10.40.90.5-0.90.9-0.80.1-0.10.60.6-0.5-0.70.20.90.90.3
Reaction time mean minus median AUC0.30.82.10.11.20.3-0.80.2-0.20.51.40.7-1.31.3-1.2-0.0-0.00.80.8-0.6-1.00.21.41.40.6
Reaction time num false alarms1.11.63.0-1.4-1.2-1.41.21.4-1.4-1.4-1.0-1.30.9-0.91.0-1.41.4-1.3-1.51.31.2-1.7-0.7-0.8-1.3
Reaction time num false alarms AUC1.32.03.4-1.6-1.3-1.81.41.6-1.6-1.5-1.2-1.51.0-1.01.2-1.61.6-1.4-1.61.41.3-1.9-0.9-1.0-1.5
Reaction time trials correct on left0.10.10.4-0.70.1-0.50.50.5-0.5-0.50.1-0.40.2-0.20.1-0.60.6-0.3-0.30.40.2-0.50.20.2-0.1
Reaction time trials on left0.10.20.5-0.70.1-0.50.50.5-0.5-0.50.1-0.40.2-0.20.1-0.60.6-0.3-0.30.40.2-0.50.30.2-0.1
Reaction time mean0.10.20.8-0.30.5-0.6-0.10.3-0.3-0.10.70.1-0.50.5-0.4-0.20.20.20.1-0.1-0.3-0.10.90.9-0.2
Reaction time mean AUC0.10.20.7-0.50.5-0.80.00.4-0.4-0.20.6-0.1-0.40.4-0.4-0.30.30.1-0.0-0.0-0.3-0.20.80.8-0.3
Median of all reaction times0.10.20.9-0.50.2-0.90.20.5-0.5-0.40.2-0.3-0.00.0-0.0-0.40.4-0.2-0.30.20.0-0.40.50.5-0.6
Reaction time omissions0.20.41.1-1.0-0.3-0.70.41.1-1.1-0.60.0-0.4-0.20.2-0.1-1.01.0-0.3-0.50.50.1-0.90.20.1-0.1
Reaction time false alarm rate0.60.91.4-0.9-1.1-1.10.90.9-0.9-1.0-1.0-1.00.7-0.70.9-0.90.9-0.9-1.10.90.9-1.2-0.8-0.8-1.2
Reaction time premature initiation rate0.00.10.20.20.10.5-0.30.1-0.10.30.20.3-0.20.2-0.00.2-0.20.20.5-0.1-0.10.3-0.3-0.4-0.2
Reaction time premature initiations0.00.00.2-0.20.00.20.00.5-0.5-0.00.20.0-0.10.10.1-0.20.20.00.30.1-0.0-0.1-0.2-0.3-0.3
Std. dev. reaction times0.30.62.00.11.00.0-0.60.2-0.20.41.30.5-1.01.0-1.00.0-0.00.60.6-0.5-0.80.21.41.40.1
Reaction time trials completed0.10.20.5-0.70.1-0.50.50.5-0.5-0.50.1-0.40.2-0.20.1-0.60.6-0.3-0.30.40.2-0.50.30.2-0.1
Reaction time trials AUC0.10.30.8-0.9-0.1-0.70.70.7-0.7-0.6-0.0-0.50.3-0.30.2-0.80.7-0.4-0.40.50.3-0.70.20.1-0.1
Run reversals in cocaine runway, females0.40.41.3-0.00.80.0-0.4-0.10.10.30.80.5-0.90.9-0.90.1-0.10.60.2-0.5-0.70.11.21.10.1
Run reversals in cocaine runway, males0.30.31.4-1.00.2-1.20.60.5-0.5-0.70.1-0.5-0.10.1-0.3-0.40.4-0.3-0.60.50.1-0.3-0.3-0.30.4
Latency to leave start box in cocaine runway0.10.10.9-0.20.2-0.1-0.00.1-0.10.00.40.1-0.20.2-0.2-0.20.20.20.2-0.1-0.30.10.90.9-0.2
Latency to leave start box in cocaine runway, F0.20.20.6-0.70.1-0.60.40.6-0.6-0.50.0-0.3-0.10.1-0.1-0.80.8-0.2-0.40.40.1-0.50.30.3-0.7
Latency to leave start box in cocaine runway, M0.10.10.50.5-0.20.4-0.2-0.40.40.30.20.20.1-0.10.20.1-0.10.10.3-0.2-0.10.30.70.70.2
Std. dev. time between licks in bursts0.50.71.71.2-0.11.2-0.8-1.31.30.80.50.8-0.70.7-0.71.1-1.10.70.8-0.6-0.61.0-0.2-0.2-0.1
Total sessions with >9 infusions1.72.13.8-1.9-1.3-1.71.61.9-1.9-1.5-1.2-1.51.3-1.31.3-1.41.4-1.4-1.61.31.3-1.3-0.9-0.9-1.1
Short access day 1 total inactive lever presses0.60.81.71.30.21.3-1.0-1.31.31.00.40.9-0.50.5-0.41.0-1.00.80.9-0.9-0.71.00.70.7-0.1
Short access day 10 total inactive lever presses2.04.88.02.81.42.7-2.3-2.82.82.51.22.3-1.81.8-1.62.7-2.62.22.4-2.3-2.02.61.51.51.2
Short access day 1 total infusions0.00.00.20.0-0.40.40.00.1-0.1-0.0-0.3-0.10.1-0.10.10.0-0.0-0.2-0.40.20.2-0.0-0.1-0.1-0.2
Short access day 10 total infusions0.50.61.1-1.0-0.8-0.90.91.0-1.0-0.8-0.7-0.80.9-0.90.8-0.60.6-0.8-0.80.60.7-0.5-0.4-0.4-0.8
Short access total infusions0.91.21.7-1.2-1.2-1.01.21.3-1.3-1.1-1.0-1.11.2-1.21.1-1.01.0-1.1-1.21.01.1-1.0-0.7-0.7-0.9
Short access day 1 locomotion1.62.04.0-1.9-1.0-2.01.61.7-1.7-1.6-0.9-1.50.9-0.90.9-1.61.6-1.3-1.21.41.1-1.6-0.9-0.9-1.4
Short access day 10 total locomotion0.40.72.20.80.50.3-0.6-1.11.10.80.30.8-0.70.7-0.61.2-1.20.91.5-1.0-0.91.40.20.20.1
Short access total locomotion1.21.41.9-1.4-1.2-1.41.31.3-1.3-1.2-1.2-1.21.2-1.21.2-1.11.1-1.1-0.71.01.1-1.0-1.3-1.3-1.3
One hour access (0.3 mA shock)0.40.51.30.80.61.1-0.8-0.30.30.90.50.8-0.50.5-0.60.7-0.70.70.6-0.8-0.60.80.80.8-0.0
Compulsive drug intake0.20.21.41.0-0.11.2-1.1-0.30.30.50.00.5-0.20.2-0.10.0-0.00.2-0.30.00.1-0.1-0.1-0.1-0.1
One hour access (shock baseline)0.00.00.1-0.1-0.00.20.30.1-0.10.1-0.10.00.3-0.30.20.2-0.20.00.2-0.3-0.00.40.30.3-0.2
Social response proportion2.42.84.01.81.42.0-1.7-1.61.61.91.11.8-1.71.7-1.51.9-1.91.81.9-1.8-1.72.00.91.01.5
Social responses0.70.92.50.70.60.8-0.8-0.80.81.00.11.0-1.11.1-1.01.0-1.01.11.6-1.1-1.11.10.20.20.6
Social time2.53.44.91.81.71.5-1.9-1.71.71.91.51.9-2.02.0-1.82.0-2.01.92.0-2.0-2.02.21.91.91.1
Soleus weight0.10.20.6-0.7-0.2-0.60.50.8-0.8-0.5-0.2-0.40.3-0.30.2-0.70.7-0.4-0.50.40.3-0.7-0.3-0.3-0.3
Bone: stiffness1.62.53.01.61.71.6-1.6-1.61.61.61.71.6-1.51.5-1.51.7-1.71.61.5-1.7-1.61.51.61.61.4
Tibialis anterior weight0.10.20.5-0.4-0.4-0.40.50.3-0.3-0.5-0.2-0.50.5-0.50.6-0.50.5-0.5-0.70.50.5-0.60.0-0.00.2
Time to tail flick, vehicle, before self-admin0.50.51.1-1.1-0.5-1.00.90.8-0.8-0.8-0.5-0.80.5-0.50.4-0.90.9-0.7-0.60.70.6-0.8-0.3-0.3-0.9
Time to tail flick, vehicle, after self-admin1.01.33.11.50.41.7-1.0-1.61.61.30.41.1-0.40.4-0.51.4-1.41.01.8-1.2-0.81.5-0.1-0.11.0
Time to tail flick, test, before self-admin0.40.41.2-0.8-0.1-0.70.60.6-0.6-0.60.3-0.50.2-0.20.2-0.80.9-0.5-0.90.40.3-0.90.50.6-1.1
Time to tail flick, test, after self-admin0.10.10.3-0.4-0.2-0.20.5-0.10.1-0.2-0.3-0.30.4-0.40.4-0.40.4-0.20.40.20.2-0.3-0.5-0.5-0.1
Delta time to tail flick, vehicle, before/after SA1.21.12.41.20.91.2-1.1-1.21.21.11.01.1-0.90.9-0.91.1-1.11.11.6-1.1-1.01.10.40.41.0
Delta time to tail flick, test, before/after SA0.30.31.9-0.1-0.50.10.3-0.00.0-0.1-0.9-0.20.6-0.60.6-0.20.2-0.30.50.30.4-0.1-1.3-1.40.5
Tibia length2.46.510.22.23.02.0-2.3-2.52.52.43.22.5-2.52.5-2.62.4-2.42.62.5-2.6-2.62.42.82.82.2
Ambulatory time before self-admin0.50.72.51.40.01.6-0.9-0.90.91.10.10.9-0.20.2-0.11.0-1.00.70.9-1.0-0.51.00.0-0.00.6
Ambulatory time after self-admin3.94.65.71.92.22.1-2.3-1.41.42.32.42.3-2.32.3-2.21.9-1.92.42.2-2.4-2.42.02.12.12.0
Bone: tissue strength3.33.34.61.91.91.9-2.2-1.71.71.91.91.9-2.02.0-2.01.7-1.71.81.6-1.7-1.81.61.71.71.2
Total heroin consumption0.40.41.30.60.40.6-0.70.1-0.10.80.30.7-0.50.5-0.50.6-0.60.71.2-0.8-0.70.60.80.80.6
Bone: trabecular number1.01.73.70.71.80.6-0.9-1.11.11.11.91.2-1.51.5-1.51.1-1.11.41.3-1.4-1.51.01.61.61.1
Bone: trabecular spacing0.60.71.81.20.41.3-1.2-0.90.90.90.40.9-0.80.8-0.71.0-1.00.70.7-0.6-0.60.70.40.41.3
Bone: trabecular thickness0.20.20.6-0.7-0.1-0.80.70.4-0.4-0.60.1-0.50.4-0.40.4-0.60.6-0.5-0.70.40.4-0.50.20.2-0.6
Bone: trabecular tissue density1.72.53.3-1.7-1.4-1.81.81.5-1.5-1.7-1.4-1.71.8-1.81.8-1.71.7-1.7-1.71.61.6-1.7-1.2-1.2-0.6
Water consumed over 24 hours0.30.41.40.41.20.2-0.4-0.60.60.60.80.6-0.70.7-0.70.5-0.50.70.7-0.7-0.80.60.70.60.5
Number of responses in last shaping day0.20.20.90.6-0.00.9-0.3-0.50.50.50.20.4-0.10.10.10.6-0.60.31.0-0.4-0.20.50.50.50.5