Zfp57

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_213565.4 0.05 0.03 1.7e-03 0.02 0.01 0.02 0.02 3.0e-04 5.7e-03 1.2e-03 5.0e-04
2 NAcc gene expression Zfp57 0.07 0.05 1.2e-04 0.04 0.03 0.02 0.04 1.7e-06 2.8e-05 8.0e-04 3.5e-06
3 Brain gene expression Zfp57 0.05 0.03 1.6e-03 0.01 0.02 0.01 0.01 1.6e-02 1.0e-02 3.3e-02 2.8e-02
4 PL isoform ratio XM_039098787.2 0.04 0.02 1.1e-03 0.03 0.03 0.02 0.02 7.2e-04 2.8e-04 1.7e-03 9.7e-04
5 Brain alternative polyA NM_213565.4 0.08 0.05 9.2e-06 0.02 0.04 0.03 0.02 6.3e-03 2.1e-04 7.5e-04 4.3e-03
6 Brain alternative polyA XM_063279194.1 0.08 0.05 1.1e-05 0.02 0.04 0.03 0.02 6.6e-03 2.3e-04 7.0e-04 4.5e-03
7 Brain isoform ratio XM_039098787.2 0.07 0.04 9.6e-06 0.04 0.04 0.03 0.04 2.8e-04 1.2e-04 5.9e-04 1.4e-04
8 PL isoform ratio NM_213565.4 0.04 0.03 4.1e-04 0.01 0.03 0.02 0.03 4.3e-02 1.6e-04 3.5e-03 6.8e-04
9 NAcc isoform ratio NM_213565.4 0.06 0.04 8.9e-05 0.03 0.02 0.03 0.03 3.4e-05 2.0e-04 7.5e-06 3.8e-05
10 NAcc isoform ratio XM_039098787.2 0.06 0.04 1.6e-04 0.03 0.02 0.04 0.03 6.0e-05 6.3e-04 4.6e-06 1.0e-04
11 Brain isoform ratio NM_213565.4 0.07 0.04 5.5e-06 0.06 0.04 0.04 0.04 3.9e-06 7.9e-05 1.9e-04 9.8e-05
12 NAcc alternative polyA XM_063279194.1 0.04 0.03 1.3e-03 0.02 0.01 0.02 0.02 4.2e-04 2.9e-03 1.6e-04 3.6e-04
13 Adipose mRNA stability Zfp57 0.07 0.05 2.5e-04 0.04 0.01 0.03 0.03 8.4e-05 8.2e-03 7.1e-04 3.0e-04
14 Liver gene expression Zfp57 0.04 0.03 1.6e-05 0.05 0.04 0.06 0.04 3.3e-06 2.1e-05 1.0e-06 1.2e-05
15 Adipose gene expression Zfp57 0.12 0.07 4.5e-11 0.09 0.09 0.07 0.08 4.0e-10 8.5e-10 1.2e-08 1.8e-09
16 Adipose isoform ratio XM_063279197.1 0.04 0.03 2.2e-04 0.03 0.02 0.01 0.02 3.5e-04 2.2e-03 6.3e-02 4.7e-03
17 Adipose alternative TSS XM_063279196.1 0.03 0.02 1.3e-03 0.02 0.02 0.02 0.02 2.3e-03 1.2e-03 2.5e-03 1.4e-03
18 Adipose alternative TSS XM_063279194.1 0.03 0.02 1.3e-03 0.02 0.03 0.02 0.03 1.3e-03 7.0e-04 5.5e-03 8.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.91.63.01.61.6-0.81.7-0.70.71.1-1.7-0.1-0.00.7-0.1-0.7-1.7-1.61.6-1.7-1.7
Area under the delay curve1.01.63.8-0.1-0.10.1-0.90.4-0.4-0.91.11.0-0.9-1.5-1.11.91.71.9-1.91.71.7
BMI with tail1.13.78.21.31.3-2.20.6-2.02.01.3-0.32.9-2.81.5-2.52.72.31.5-1.51.72.0
BMI without tail0.84.111.30.50.5-1.1-0.7-0.70.7-0.21.02.7-2.5-0.2-2.63.43.02.5-2.52.82.9
Body weight2.912.826.8-2.8-2.81.5-4.12.1-2.1-3.44.42.0-1.7-2.5-1.84.24.55.0-5.05.25.0
Weight adjusted by age0.92.65.7-1.3-1.31.6-2.12.0-1.9-2.32.10.8-0.7-2.4-0.60.90.61.7-1.71.71.5
Bone surface0.51.13.0-0.7-0.71.5-1.21.7-1.7-1.71.1-0.60.6-1.70.4-0.1-0.70.4-0.40.30.0
Bone volume0.10.31.20.30.30.6-0.30.9-0.9-0.90.20.1-0.2-1.1-0.20.3-0.50.1-0.1-0.0-0.2
Breakpoint value in progressive ratio session0.61.14.80.40.4-1.01.0-1.51.41.7-1.0-0.20.12.20.3-0.8-0.4-1.01.0-0.8-0.6
Number of licking bursts0.20.72.1-1.4-1.40.9-0.90.8-0.8-0.70.9-0.91.0-0.71.0-0.5-0.10.4-0.40.20.2
Context. condit. distance diff. score3.44.110.1-1.2-1.22.0-0.31.6-1.6-0.6-0.1-2.82.6-0.02.9-3.2-2.6-2.32.3-2.3-2.5
Locomotion velocity, session 10.40.51.6-0.6-0.60.9-0.60.8-0.8-0.70.5-1.01.0-0.40.8-0.8-1.30.0-0.0-0.2-0.3
Locomotion distance, session 10.91.22.11.41.4-1.21.5-1.21.21.4-1.50.1-0.21.4-0.2-0.6-0.8-1.01.0-1.0-0.9
Locomotion velocity, session 20.20.20.4-0.5-0.5-0.0-0.4-0.20.20.10.4-0.50.60.60.5-0.3-0.30.6-0.60.40.5
Locomotion distance, session 20.40.61.20.60.6-0.20.8-0.30.30.6-0.9-0.50.50.80.5-1.0-1.1-1.11.1-1.1-1.1
Locomotion velocity, session 30.70.82.01.01.0-1.30.8-1.41.41.2-0.70.8-0.71.3-0.70.50.80.2-0.20.20.4
Locomotion distance, session 30.80.91.90.60.6-0.51.1-0.70.71.1-1.2-0.50.41.00.5-1.0-1.0-1.31.3-1.4-1.3
Stereotopy head waving bouts, day 31.21.42.9-1.7-1.71.3-1.71.2-1.2-1.31.7-0.60.7-0.80.70.10.61.1-1.11.11.0
Stereotopy head waving duration, day 30.81.02.0-1.3-1.30.9-1.40.9-0.9-1.11.4-0.20.3-0.70.30.50.91.2-1.21.21.1
Locomotion velocity, session 71.41.55.00.20.20.40.90.3-0.30.2-1.1-1.10.90.11.1-2.1-2.2-1.61.6-1.9-2.0
Locomotion distance, session 71.41.74.31.11.1-0.41.6-0.50.51.0-1.7-0.30.10.80.5-1.5-1.5-2.02.0-2.1-2.1
Stereotopy head waving bouts, day 71.51.83.9-0.9-0.90.8-1.51.1-1.1-1.61.60.5-0.3-1.7-0.51.30.92.0-2.01.81.7
Stereotopy head waving duration, day 71.51.94.3-0.8-0.80.8-1.61.1-1.1-1.61.70.5-0.3-1.7-0.51.31.02.1-2.11.91.8
Locomotion velocity, session 83.64.38.3-2.8-2.82.9-2.42.7-2.7-2.52.2-2.12.2-1.72.2-1.4-1.10.6-0.60.40.1
Locomotion distance, session 82.03.07.3-0.7-0.71.60.01.2-1.2-0.3-0.3-2.32.10.22.3-2.7-2.2-2.22.2-2.1-2.3
Degree of sensitization distance0.40.51.3-0.7-0.71.1-0.71.1-1.1-1.00.7-0.40.3-1.00.5-0.5-0.2-0.00.0-0.0-0.2
Degree of sensitization stereotypy0.60.61.6-0.2-0.20.3-0.80.6-0.5-0.90.90.5-0.4-1.0-0.50.90.51.3-1.31.11.0
Conditioned locomotion1.21.33.9-0.7-0.70.1-1.20.1-0.1-0.61.30.7-0.5-0.6-0.51.31.52.0-2.01.81.9
Cocaine response after cond. corrected0.30.41.80.60.6-0.90.7-1.01.01.0-0.6-0.10.11.40.1-0.2-0.3-0.00.0-0.2-0.1
Cocaine response after cond. not corrected0.40.51.1-0.8-0.80.6-1.00.6-0.6-0.71.0-0.40.5-0.30.50.20.31.0-1.00.90.8
Cocaine response before conditioning5.06.013.0-2.1-2.12.5-3.23.0-3.0-3.53.20.2-0.0-3.6-0.11.41.72.6-2.62.62.3
Saline control response1.01.44.01.11.1-0.90.1-0.50.50.00.11.8-1.6-0.9-1.82.01.41.3-1.31.21.3
Bone: connectivity density1.21.95.61.01.00.01.3-0.00.00.6-1.4-1.21.00.40.9-1.7-2.4-2.02.0-2.1-2.2
Bone: cortical apparent density0.91.42.61.31.3-1.50.9-1.41.41.0-0.71.6-1.60.6-1.51.61.10.5-0.50.50.7
Bone: cortical area0.61.01.9-1.1-1.11.0-1.21.2-1.2-1.41.30.4-0.4-1.3-0.40.80.80.8-0.81.00.9
Bone: cortical porosity0.10.10.30.10.1-0.0-0.10.1-0.1-0.20.10.3-0.2-0.4-0.20.40.60.3-0.30.30.3
Bone: cortical porosity0.40.41.4-0.7-0.70.8-0.81.0-1.0-1.00.8-0.20.2-1.20.20.20.30.4-0.40.40.3
Bone: cortical thickness1.32.25.51.31.3-1.70.7-1.31.30.7-0.42.4-2.30.4-2.32.21.80.9-0.91.11.3
Bone: cortical thickness2.42.95.42.22.2-2.31.6-2.12.11.8-1.42.3-2.31.2-2.01.61.10.1-0.10.20.5
Bone: cortical tissue density0.71.12.11.21.2-1.40.8-1.31.30.9-0.71.5-1.40.6-1.41.41.00.5-0.50.50.7
Condit. Reinf. active minus inactive responses0.00.10.1-0.0-0.0-0.00.1-0.10.10.1-0.2-0.40.40.30.3-0.2-0.4-0.30.3-0.3-0.3
Condit. Reinf. active-inactive response ratio0.40.40.90.40.4-0.80.2-0.80.80.5-0.10.6-0.60.5-0.70.90.50.7-0.70.70.8
Condit. Reinf. active responses0.30.41.00.30.3-0.40.8-0.50.50.8-0.8-0.30.21.00.3-0.5-0.4-1.01.0-0.9-0.8
Condit. Reinf. inactive responses1.62.04.41.11.1-1.01.8-1.21.21.7-1.9-0.1-0.21.70.1-1.1-0.8-2.12.1-1.9-1.8
Incentive salience index mean0.60.82.1-1.0-1.00.7-0.30.4-0.4-0.10.1-1.41.40.61.3-1.2-0.9-0.80.8-0.7-0.7
Condit. Reinf. lever presses1.92.96.9-1.6-1.61.2-0.10.5-0.50.3-0.1-2.62.41.42.5-2.6-1.7-1.91.9-1.7-1.8
Condit. Reinf. active minus inactive responses0.71.12.3-0.8-0.81.0-1.31.2-1.2-1.41.30.10.0-1.5-0.10.70.81.2-1.21.11.0
Condit. Reinf. active-inactive response ratio1.21.93.6-1.4-1.41.1-1.81.3-1.3-1.71.80.10.1-1.50.00.91.01.9-1.91.71.6
Condit. Reinf. active responses0.10.20.5-0.3-0.30.6-0.30.7-0.7-0.50.2-0.50.5-0.60.4-0.4-0.1-0.30.3-0.3-0.4
Condit. Reinf. inactive responses0.50.72.20.50.5-0.20.9-0.30.30.7-1.0-0.50.40.50.4-1.0-0.7-1.51.5-1.4-1.4
Condit. Reinf. lever presses0.81.23.1-0.3-0.30.80.40.7-0.7-0.2-0.6-1.21.1-0.51.0-1.5-1.4-1.61.6-1.6-1.8
Condit. Reinf. lever reinforcers received0.20.30.6-0.4-0.40.8-0.20.8-0.8-0.50.1-0.70.7-0.60.6-0.7-0.4-0.50.5-0.6-0.7
Conditioned reinforcement - actives0.31.33.51.41.4-0.60.0-0.20.2-0.30.11.9-1.7-1.8-1.71.31.10.9-0.90.91.0
Conditioned reinforcement - inactives0.30.83.20.80.8-0.70.4-0.40.50.2-0.21.8-1.8-1.2-1.50.90.60.4-0.40.50.6
Conditioned locomotion0.30.42.70.00.00.3-0.50.5-0.5-0.60.50.4-0.4-1.7-0.50.80.60.5-0.50.60.5
Patch foraging indifference point 0 sec0.30.83.81.91.9-0.40.80.0-0.0-0.1-0.81.2-1.1-0.9-1.20.6-0.5-0.30.3-0.4-0.4
Patch foraging indifference point AUC0.61.33.6-0.8-0.80.6-1.20.9-0.9-1.31.30.7-0.7-1.4-0.71.21.91.4-1.41.41.3
Delay disc. indifference point, 0s delay0.70.82.0-0.9-0.90.4-1.10.5-0.5-0.71.1-0.30.5-0.30.20.91.11.4-1.41.21.2
Delay disc. indifference point, 16s delay1.42.04.81.71.7-1.50.7-1.11.10.5-0.52.2-2.1-0.5-2.12.11.51.2-1.21.01.1
Delay disc. indifference point, 2s delay1.51.74.0-1.0-1.00.5-1.40.7-0.7-1.21.50.6-0.4-1.3-0.41.31.52.0-2.01.81.7
Delay disc. indifference point, 24s delay0.40.72.00.60.6-0.1-0.30.3-0.3-0.60.41.1-1.0-1.0-1.11.40.71.1-1.10.90.9
Delay disc. indifference point, 4s delay2.52.66.1-1.0-1.00.8-1.81.0-1.0-1.62.00.5-0.3-1.7-0.51.81.82.5-2.52.32.2
Delay disc. indifference point, 8s delay0.30.41.90.20.20.2-0.40.5-0.5-0.70.40.6-0.6-1.4-0.71.10.70.7-0.70.50.5
Indifference point function ln k0.30.84.2-0.7-0.71.0-0.30.8-0.8-0.50.2-0.90.9-0.41.1-1.1-2.1-0.60.6-0.7-0.8
Indifference point function log k0.30.84.2-0.7-0.71.0-0.30.8-0.8-0.50.2-0.90.9-0.41.1-1.1-2.1-0.60.6-0.7-0.8
Patch foraging total patch changes 0 sec0.31.04.22.12.1-0.60.8-0.00.0-0.1-0.81.4-1.3-1.1-1.50.8-0.3-0.20.2-0.2-0.3
Patch foraging total patch changes 12 sec0.70.92.81.71.7-0.80.8-0.40.40.2-0.71.5-1.5-0.5-1.60.91.00.0-0.00.10.1
Patch foraging total patch changes 18 sec0.92.15.12.32.3-1.82.0-1.51.51.5-1.91.5-1.60.9-1.40.50.2-0.90.9-0.9-0.8
Patch foraging total patch changes 24 sec0.72.47.82.82.8-1.82.1-1.31.31.2-2.01.6-1.60.0-1.80.6-0.5-0.70.7-0.9-0.8
Patch foraging total patch changes 6 sec1.11.85.52.32.3-1.30.9-0.70.70.3-0.72.0-1.9-0.6-2.11.71.30.5-0.50.50.6
Patch foraging time to switch 0 sec0.62.25.41.71.7-2.11.7-2.32.32.2-1.60.9-0.92.3-0.90.40.3-0.30.3-0.30.0
Patch foraging water rate 0 sec0.20.84.80.20.21.0-0.71.5-1.5-1.60.60.6-0.6-2.2-0.60.2-0.00.3-0.30.2-0.0
Patch foraging water rate 12 sec0.00.20.40.60.6-0.60.6-0.40.40.4-0.60.5-0.60.0-0.5-0.10.4-0.10.1-0.3-0.2
Patch foraging water rate 18 sec0.10.20.8-0.1-0.10.5-0.40.6-0.6-0.60.4-0.10.1-0.90.00.10.50.3-0.30.20.1
Patch foraging water rate 24 sec0.20.42.00.10.1-0.0-0.30.1-0.1-0.30.30.6-0.7-0.5-0.70.71.40.8-0.80.70.7
Patch foraging water rate 6 sec0.20.30.70.90.9-0.70.8-0.70.70.7-0.80.4-0.5-0.1-0.5-0.20.1-0.40.4-0.4-0.3
Seeking ratio, delayed vs. immediate footshock0.20.30.8-0.7-0.70.2-0.70.2-0.2-0.40.80.10.0-0.0-0.10.40.60.8-0.80.90.9
Distance traveled before self-admin0.61.33.6-1.9-1.91.4-0.91.2-1.2-0.90.8-1.61.5-0.91.4-0.70.5-0.40.4-0.2-0.4
Distance traveled after self-admin0.71.34.7-2.2-2.21.0-1.20.9-0.9-0.91.2-1.21.2-0.31.1-0.01.20.6-0.60.60.5
Extensor digitorum longus weight0.62.66.7-1.4-1.42.3-1.42.5-2.5-2.31.2-1.31.4-2.61.2-0.8-1.60.0-0.0-0.2-0.6
Bone: elastic displacement0.20.30.80.60.6-0.70.2-0.50.50.2-0.10.5-0.3-0.3-0.70.90.30.7-0.70.60.7
Bone: elastic work0.40.51.7-0.2-0.2-0.3-0.4-0.20.2-0.20.50.4-0.2-0.4-0.61.30.91.1-1.11.11.2
Bone: endosteal estimation3.99.618.2-4.0-4.04.0-4.34.1-4.1-4.24.2-1.82.0-3.31.90.20.62.2-2.22.21.8
Bone: endosteal perimeter2.86.814.4-3.5-3.53.8-2.93.6-3.6-3.22.7-2.72.7-2.42.5-1.8-1.20.1-0.10.1-0.3
Epididymis fat weight4.120.940.85.85.8-6.44.6-5.85.84.7-4.15.8-5.93.3-5.64.03.50.4-0.40.61.3
Delta time in closed arm before/after self-admin0.30.30.80.00.0-0.2-0.20.0-0.0-0.30.20.7-0.6-0.9-0.50.70.10.8-0.80.60.6
Delta time in open arm before/after self-admin0.50.62.1-1.2-1.20.7-0.50.8-0.8-0.80.5-0.60.5-1.30.4-0.11.5-0.10.10.0-0.1
Diff in mean of infusions in LGA sessions1.52.85.30.90.9-1.21.9-1.71.72.1-2.0-0.70.61.60.9-1.7-2.3-2.12.1-2.1-1.9
Delay discount exponential model param1.21.63.80.10.1-0.10.9-0.40.40.9-1.1-1.10.91.51.1-1.9-1.7-1.91.9-1.7-1.7
Extinction: sum of active levers before priming1.11.65.80.70.7-1.21.4-1.61.61.9-1.4-0.20.12.40.3-1.1-0.9-1.41.4-1.2-1.0
Active lever presses in extinction session 62.12.16.01.51.5-2.21.7-2.42.42.3-1.50.8-0.81.8-0.90.40.6-0.50.5-0.30.1
Bone: final force1.11.75.1-0.1-0.1-0.6-0.5-0.20.2-0.40.71.7-1.7-0.3-1.52.32.11.6-1.61.81.9
Bone: final moment0.81.33.8-0.3-0.3-0.2-0.70.2-0.2-0.70.81.4-1.4-0.7-1.31.91.81.4-1.41.61.6
Food consumed during 24 hour testing period0.61.12.4-1.6-1.61.1-1.51.0-1.0-1.11.4-0.81.0-0.80.8-0.20.61.0-1.00.90.8
Glucose5.38.415.3-3.2-3.23.9-2.43.6-3.6-2.92.1-3.83.9-2.43.8-3.0-2.8-0.70.7-0.9-1.4
Heart weight1.72.75.3-0.5-0.50.7-1.51.3-1.2-1.91.71.6-1.4-2.0-1.31.91.72.3-2.32.12.0
Delay discount hyperbolic model param1.21.63.90.10.10.00.9-0.30.30.9-1.1-1.11.01.41.1-1.9-1.7-2.02.0-1.8-1.7
Intermittent access intake day 1-15 change0.00.10.8-0.1-0.10.0-0.1-0.10.10.10.10.1-0.1-0.40.0-0.00.9-0.10.10.10.1
Intermittent access intake escalation0.10.42.50.20.2-0.50.0-0.50.50.30.10.7-0.7-0.2-0.60.71.60.4-0.40.60.7
Intermittent access intake escalation 20.50.92.3-1.2-1.21.3-1.11.3-1.3-1.11.0-0.70.6-1.50.8-0.20.6-0.10.10.1-0.0
Intermitt. access day 1 inactive lever presses0.11.03.2-1.8-1.81.3-1.11.0-1.0-0.81.0-1.21.2-0.61.2-0.4-0.50.0-0.00.1-0.0
Intermitt. access day 15 inactive lever presses0.21.23.6-1.4-1.41.2-1.31.3-1.3-1.41.3-0.50.6-1.90.60.40.01.0-1.00.80.7
Intermitt. access escalation Index0.61.88.90.20.2-0.61.1-1.21.21.6-1.2-1.11.03.01.0-1.5-1.1-1.51.5-1.4-1.3
Intermittent access day 1 total infusions0.30.91.91.31.3-1.41.2-1.31.31.1-1.11.1-1.10.1-1.10.60.3-0.30.3-0.2-0.1
Intermittent access day 15 total infusions0.51.34.81.01.0-1.50.7-1.31.30.9-0.51.3-1.3-0.1-1.31.32.20.5-0.50.70.9
Intermittent access terminal intake (last 3 days)0.71.34.41.11.1-1.20.5-0.90.90.5-0.41.5-1.5-1.0-1.51.52.10.6-0.60.80.9
Intermittent access total infusions0.70.93.10.90.9-1.00.4-0.80.80.4-0.31.2-1.2-0.8-1.31.31.80.5-0.50.70.8
Intermittent access day 1 locomotion0.10.20.6-0.0-0.0-0.50.0-0.60.60.40.00.3-0.3-0.2-0.40.80.60.5-0.50.60.6
Intermittent access day 15 total locomotion0.52.04.9-0.7-0.70.2-1.40.4-0.4-0.91.61.0-0.8-1.3-1.02.02.22.0-2.02.12.1
Intermittent access total locomotion1.51.75.1-0.8-0.80.1-1.20.2-0.2-0.71.40.9-0.8-1.2-0.91.92.21.8-1.81.91.9
Intermittent access standard deviation0.31.66.60.60.60.0-0.50.5-0.5-0.90.61.8-1.7-2.6-1.61.32.10.9-0.91.11.1
Left kidney weight1.08.415.6-2.2-2.21.4-3.22.1-2.1-3.13.41.5-1.2-3.0-1.63.43.73.8-3.83.93.8
Right kidney weight1.711.521.6-2.4-2.41.8-3.82.6-2.6-3.74.11.8-1.5-3.6-1.83.83.84.6-4.64.64.4
Cocaine induced anxiety0.61.74.0-1.6-1.61.7-1.01.4-1.4-1.00.8-2.01.9-0.51.8-1.2-0.9-0.60.6-0.6-0.7
Post-drug Anxiety0.80.92.4-1.3-1.30.9-0.40.5-0.6-0.20.2-1.41.30.11.6-1.4-1.1-0.70.7-0.7-0.8
Baseline Anxiety1.32.24.51.51.5-2.01.9-2.12.12.1-1.81.2-1.32.1-0.8-0.5-0.4-0.80.8-0.9-0.6
Tail length2.815.228.6-4.6-4.64.2-5.34.6-4.6-5.25.4-1.01.4-4.40.81.72.73.7-3.73.93.4
Length with tail5.524.347.0-5.6-5.65.5-6.76.1-6.1-6.96.7-1.11.6-5.91.01.93.04.6-4.64.74.1
Length without tail2.211.321.0-3.8-3.83.0-4.43.4-3.4-4.24.60.00.3-3.30.12.02.94.0-4.04.03.7
Times rat made contact with spout2.02.34.61.71.7-1.82.2-1.91.92.1-2.20.4-0.41.7-0.5-0.5-0.8-1.31.3-1.4-1.2
Lifetime Intake0.70.82.50.70.7-0.80.2-0.60.60.2-0.11.3-1.2-0.9-1.31.41.60.7-0.70.80.9
Liver weight, left2.94.912.9-3.6-3.62.9-2.92.7-2.7-2.52.7-2.12.2-1.32.1-0.50.30.8-0.81.00.7
Liver weight, right4.07.013.8-3.6-3.63.1-3.73.1-3.0-3.33.7-1.31.5-2.41.30.71.22.3-2.32.42.1
Locomotor activity3.65.611.4-3.3-3.33.3-2.93.4-3.4-3.22.7-1.91.9-2.91.8-0.50.10.4-0.40.70.3
Locomotor testing distance1.12.75.6-1.9-1.92.3-1.62.4-2.4-2.11.4-1.71.7-2.31.6-0.8-0.7-0.10.1-0.1-0.4
Locomotor testing rearing0.51.73.5-1.7-1.71.8-1.61.9-1.9-1.71.5-1.21.1-1.41.0-0.10.40.2-0.20.40.2
Locomotion in novel chamber0.10.10.40.10.10.4-0.40.5-0.5-0.60.4-0.00.1-0.5-0.00.20.70.2-0.20.30.2
Locomotion in novel chamber post-restriction0.20.61.6-0.5-0.50.0-0.60.3-0.2-0.60.70.5-0.4-1.2-0.41.10.11.3-1.31.01.0
Fecal boli incidents, locomotor time 10.20.51.10.20.2-0.00.6-0.00.00.3-0.7-0.90.80.10.6-1.1-0.9-0.90.9-1.0-1.0
Change in fecal boli incidents, locomotor task0.80.92.8-0.4-0.40.0-1.00.1-0.0-0.41.10.8-0.6-0.2-0.51.20.61.7-1.71.51.5
Time >=10cm from walls, locomotor time 10.91.13.1-1.8-1.81.1-1.41.0-1.0-1.11.4-0.80.8-0.60.70.10.50.9-0.91.00.9
Bouts of movement, locomotor time 10.70.91.8-0.6-0.61.3-0.41.3-1.3-1.00.3-1.11.0-1.20.9-1.0-1.0-0.90.9-0.8-1.0
Total resting periods, locomotor time 10.50.61.4-0.7-0.71.2-0.71.2-1.2-1.00.5-0.90.9-1.00.7-0.6-0.4-0.40.4-0.3-0.5
Rest time, locomotor task time 10.61.02.0-1.4-1.41.1-1.41.0-1.0-1.11.4-0.70.7-0.50.50.10.91.0-1.00.90.8
Distance moved, locomotor task time 10.10.20.70.70.7-0.20.30.1-0.1-0.2-0.30.8-0.8-0.5-0.70.4-0.80.0-0.0-0.0-0.1
Vertical activity count, locomotor time 10.00.21.30.50.5-0.10.30.1-0.1-0.1-0.30.5-0.5-0.7-0.40.0-1.1-0.30.3-0.2-0.2
Time >=10cm from walls, locomotor time 20.30.91.7-1.1-1.11.0-1.21.2-1.2-1.31.2-0.40.5-1.20.40.3-0.20.9-0.90.80.6
Bouts of movement, locomotor time 20.62.03.9-2.0-2.01.7-1.81.7-1.7-1.71.8-1.41.5-1.21.0-0.11.30.6-0.60.80.7
Total resting periods, locomotor time 20.62.65.4-2.3-2.32.1-2.02.0-2.0-1.91.9-1.71.9-1.21.3-0.51.00.5-0.50.70.5
Rest time, locomotor task time 21.52.65.4-2.3-2.32.2-1.81.8-1.8-1.41.6-2.22.2-0.22.1-1.3-0.2-0.00.00.0-0.2
Distance moved, locomotor task time 21.01.44.11.71.7-1.20.8-0.80.80.3-0.72.0-2.0-0.3-1.81.50.60.6-0.60.50.6
Vertical activity count, locomotor time 20.20.51.30.90.9-0.70.7-0.50.50.4-0.71.1-1.10.2-0.90.4-0.4-0.40.4-0.2-0.1
Light reinforcement 10.10.31.01.01.0-0.70.5-0.50.50.3-0.40.7-0.60.1-0.80.30.10.4-0.40.10.2
Light reinforcement 21.02.34.9-0.9-0.91.0-1.81.4-1.4-1.91.90.5-0.3-1.9-0.61.11.02.2-2.22.01.8
Bone: marrow area3.89.217.5-3.9-3.93.9-4.24.0-4.0-4.14.1-1.81.9-3.21.80.20.62.2-2.22.21.8
Bone: maximum diameter2.04.09.0-2.6-2.63.0-2.42.9-2.9-2.62.2-1.81.8-2.01.7-1.1-0.70.1-0.10.3-0.1
Bone: maximum force0.81.53.8-0.6-0.60.1-1.00.4-0.4-0.91.21.2-1.2-0.8-1.12.01.71.6-1.61.71.7
Bone: maximum moment0.71.42.6-0.9-0.90.6-1.21.0-1.0-1.41.30.9-0.9-1.4-0.81.61.41.4-1.41.51.4
Mean time between licks in bursts0.53.26.3-2.3-2.32.5-2.02.3-2.3-2.01.8-2.02.0-1.72.0-1.4-0.60.2-0.20.1-0.1
Mean num. licks in bursts0.72.04.82.22.2-1.71.8-1.61.61.7-1.81.0-1.11.4-1.10.1-0.3-1.01.0-0.9-0.8
Cd content in liver0.30.31.21.11.1-0.50.6-0.30.30.2-0.60.8-0.8-0.2-0.70.2-0.6-0.20.2-0.2-0.2
Co content in liver0.70.92.10.80.8-1.20.8-1.01.00.6-0.61.5-1.40.2-1.31.30.60.5-0.50.50.6
Cu content in liver2.32.75.32.32.3-1.92.3-1.91.92.0-2.30.9-1.01.4-1.10.0-0.5-1.51.5-1.4-1.2
Fe content in liver1.11.42.11.41.4-1.40.5-1.31.30.9-0.31.4-1.30.7-1.41.31.11.1-1.11.01.2
K content in liver0.60.61.20.30.3-0.71.1-0.80.81.0-1.10.0-0.10.8-0.1-0.5-0.5-0.90.9-0.9-0.9
Mg content in liver0.60.61.4-0.8-0.80.7-0.10.5-0.5-0.1-0.1-1.11.0-0.11.0-1.2-1.0-0.90.9-0.9-1.0
Mn content in liver2.83.17.4-2.0-2.02.1-1.11.7-1.7-1.10.8-2.72.7-0.52.6-2.3-1.6-1.01.0-1.1-1.3
Na content in liver0.60.71.60.80.8-1.31.0-1.11.11.0-0.91.0-1.10.5-1.00.70.9-0.00.0-0.00.1
Rb content in liver0.30.41.10.50.5-0.20.7-0.20.20.5-0.8-0.20.10.2-0.0-0.5-0.7-1.01.0-1.0-1.0
Se content in liver2.02.44.7-1.8-1.82.2-1.92.0-2.0-1.81.8-1.82.0-1.31.6-0.9-0.90.4-0.40.40.2
Sr content in liver0.40.41.2-1.1-1.10.5-0.80.4-0.4-0.50.9-0.20.3-0.20.30.20.50.5-0.50.70.6
Zn content in liver0.30.41.2-0.2-0.20.8-0.20.8-0.8-0.60.1-0.70.7-0.50.5-0.6-1.1-0.70.7-0.6-0.7
Bone: minimum diameter2.34.48.9-3.0-3.03.0-2.62.8-2.8-2.52.4-2.12.1-1.82.0-1.1-0.60.4-0.40.50.2
Time in familiar zone, hab. session 13.03.36.42.12.1-2.22.5-2.32.32.5-2.50.7-0.92.2-0.6-0.3-0.5-1.61.6-1.6-1.4
Time in novel zone, hab. session 13.64.010.7-2.1-2.12.6-2.52.9-2.9-3.02.4-0.81.0-3.30.60.10.11.3-1.31.20.8
Total zone transitions, hab. session 10.50.72.10.70.7-0.10.8-0.10.10.4-0.9-0.40.40.30.4-1.0-1.4-1.11.1-1.2-1.2
Total locomotion distance, hab. session 10.40.61.10.70.7-0.50.9-0.60.60.8-1.0-0.20.20.70.2-0.8-0.8-1.01.0-1.0-1.0
Locomotion velocity, hab. session 10.50.71.20.90.9-0.91.1-1.01.01.1-1.10.1-0.21.1-0.1-0.4-0.4-0.90.9-0.8-0.7
Time in familiar zone, hab. session 20.91.02.70.80.8-1.11.3-1.31.31.5-1.30.1-0.21.6-0.2-0.30.0-1.11.1-1.0-0.8
Time in novel zone, hab. session 20.91.03.2-0.5-0.50.8-1.11.2-1.2-1.51.20.3-0.1-1.8-0.20.60.11.3-1.31.10.9
Total zone transitions, hab. session 20.20.30.60.60.6-0.70.7-0.70.70.7-0.60.5-0.50.7-0.40.0-0.1-0.20.2-0.2-0.2
Total locomotion distance, hab. session 20.70.91.71.01.0-0.81.3-0.90.91.2-1.3-0.20.11.00.2-0.9-0.9-1.11.1-1.2-1.1
Locomotion velocity, hab. session 20.81.11.91.01.0-0.81.3-1.01.01.3-1.4-0.20.21.20.3-1.0-1.0-1.41.4-1.3-1.2
Novel to familiar place preference ratio0.20.30.70.70.7-0.20.00.0-0.0-0.30.00.8-0.7-0.6-0.70.6-0.30.6-0.60.40.4
Novelty place preference0.30.40.90.50.5-0.0-0.30.3-0.2-0.50.40.8-0.7-0.9-0.80.8-0.10.9-0.90.70.7
Time in novel zone, NPP test0.50.61.30.30.30.2-0.50.5-0.5-0.80.60.8-0.7-1.2-0.70.9-0.01.1-1.10.90.9
Total zone transitions, NPP test0.50.72.50.40.40.20.60.2-0.20.1-0.8-0.70.6-0.20.5-1.2-1.6-1.21.2-1.3-1.4
Total locomotion distance, NPP test0.60.81.61.11.1-0.71.2-0.70.70.8-1.3-0.10.10.40.0-0.8-1.1-1.11.1-1.2-1.1
Locomotion velocity, NPP test1.11.63.11.41.4-0.91.7-1.01.01.3-1.8-0.30.21.00.1-1.2-1.4-1.61.6-1.7-1.6
Intraocular pressure0.30.41.50.70.70.20.50.1-0.10.1-0.6-0.30.3-0.10.3-0.7-1.2-0.90.9-1.0-1.0
Delta distance traveled before/after self-admin0.80.92.9-0.2-0.2-0.2-0.60.0-0.0-0.50.80.7-0.6-0.2-0.71.31.21.7-1.71.51.5
Delta ambulatory time before/after self-admin0.40.72.2-0.4-0.40.0-0.80.2-0.2-0.60.80.5-0.40.2-0.41.00.81.5-1.51.31.3
Parametrial fat weight0.51.13.0-0.8-0.80.1-0.90.3-0.3-0.71.10.8-0.7-0.6-0.81.41.71.4-1.41.51.5
Pavlov. Cond. lever latency2.43.06.22.52.5-2.31.8-2.12.11.7-1.62.3-2.31.0-2.21.61.1-0.10.10.10.3
Pavlov. Cond. magazine entry latency1.92.46.5-1.8-1.81.5-0.80.9-0.9-0.30.5-2.52.50.62.5-2.3-1.4-1.11.1-1.0-1.1
Pavlov. Cond. change in total contacts1.81.93.9-1.8-1.81.7-2.01.7-1.7-1.81.9-0.91.0-1.20.9-0.20.11.2-1.21.10.9
Pavlov. Cond. index score2.33.07.3-2.3-2.32.0-1.41.5-1.5-0.91.1-2.72.70.22.7-2.2-1.4-0.60.6-0.6-0.8
Pavlov. Cond. latency score2.32.96.9-2.4-2.42.1-1.51.6-1.6-1.21.3-2.62.6-0.12.5-1.9-1.2-0.40.4-0.4-0.6
Pavlov. Cond. lever contacts2.42.95.9-2.4-2.42.2-1.82.0-2.0-1.71.6-2.22.2-0.92.1-1.4-1.00.1-0.10.0-0.2
Pavlov. Cond. magazine entry number1.72.15.91.51.5-1.00.3-0.40.4-0.2-0.12.4-2.4-1.1-2.32.41.41.3-1.31.21.2
Pavlov. Cond. intertrial magazine entries1.11.33.01.71.7-1.41.5-1.21.21.1-1.41.3-1.30.6-1.30.60.0-0.40.4-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.2.32.97.3-2.2-2.21.9-1.21.3-1.3-0.80.9-2.72.70.42.6-2.3-1.5-0.80.8-0.8-1.0
Pavlov. Cond. response bias2.12.66.6-2.2-2.21.7-1.11.2-1.2-0.70.9-2.62.60.42.5-2.3-1.5-0.60.6-0.7-0.9
Pavlov. Cond. lever latency0.30.41.0-0.4-0.40.1-0.70.1-0.1-0.30.80.2-0.10.1-0.10.40.71.0-1.01.01.0
Pavlov. Cond. magazine entry latency0.20.30.5-0.7-0.70.5-0.70.5-0.5-0.60.7-0.20.3-0.50.20.30.50.4-0.40.50.5
Pavlov. Cond. change in total contacts0.00.10.40.10.1-0.1-0.10.1-0.1-0.30.10.4-0.3-0.6-0.40.50.10.4-0.40.30.2
Pavlov. Cond. index score0.10.10.4-0.3-0.30.5-0.20.5-0.5-0.40.2-0.30.4-0.60.3-0.1-0.2-0.10.1-0.1-0.2
Pavlov. Cond. latency score0.00.00.1-0.1-0.10.2-0.10.2-0.2-0.20.1-0.10.1-0.40.00.1-0.0-0.10.1-0.1-0.1
Pavlov. Cond. lever contacts0.10.20.60.30.3-0.10.50.0-0.00.1-0.6-0.10.0-0.3-0.0-0.2-0.6-0.70.7-0.7-0.8
Pavlov. Cond. magazine entry number0.20.30.70.40.4-0.40.6-0.50.50.7-0.6-0.1-0.00.80.1-0.6-0.5-0.60.6-0.6-0.5
Pavlov. Cond. intertrial magazine entries0.40.92.3-1.2-1.21.1-0.50.8-0.8-0.50.4-1.51.40.01.4-1.5-0.8-0.60.6-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.3-0.30.5-0.20.6-0.6-0.50.2-0.40.4-0.70.3-0.1-0.3-0.10.1-0.2-0.3
Pavlov. Cond. response bias0.20.20.5-0.4-0.40.6-0.10.6-0.6-0.50.0-0.50.5-0.70.4-0.4-0.5-0.40.4-0.5-0.6
Time in closed arm before self-admin0.20.30.50.60.6-0.60.5-0.70.70.7-0.40.6-0.70.7-0.40.20.3-0.20.2-0.10.0
Time in closed arm after self-admin1.61.84.61.11.1-1.50.5-1.31.30.8-0.32.1-2.10.2-1.81.81.11.2-1.21.11.3
Time in open arm before self-admin0.30.42.80.10.10.4-0.10.2-0.2-0.00.1-0.30.41.10.5-0.9-1.7-0.40.4-0.4-0.5
Time in open arm after self-admin1.01.12.0-1.1-1.11.3-0.51.1-1.1-0.60.3-1.41.30.21.4-1.4-0.6-1.01.0-0.9-1.0
Bone: periosteal estimation2.56.011.7-3.0-3.03.0-3.33.2-3.2-3.43.3-0.80.9-2.80.90.70.91.9-1.92.01.7
Bone: periosteal perimeter1.63.26.6-2.4-2.42.5-2.42.6-2.6-2.52.3-1.01.0-1.91.0-0.30.20.7-0.70.90.6
Bone: post-yield work2.23.88.5-2.3-2.32.9-1.92.8-2.8-2.31.6-2.01.9-1.82.1-1.5-1.3-0.60.6-0.5-0.9
Progressive ratio test 1 active lever presses0.71.22.31.01.0-1.50.8-1.51.51.1-0.71.3-1.30.9-1.31.11.30.3-0.30.50.7
Progressive ratio test 1 breakpoint0.61.12.10.90.9-1.50.8-1.41.41.1-0.61.3-1.30.8-1.31.21.30.4-0.40.60.8
Progressive ratio test 1 inactive lever presses0.71.83.81.81.8-1.71.5-1.51.51.3-1.41.9-2.00.6-1.70.90.4-0.40.4-0.3-0.1
Progressive ratio test 2 active lever presses1.01.53.31.51.5-1.81.3-1.81.81.6-1.21.1-1.10.5-1.10.81.4-0.20.2-0.00.2
Progressive ratio test 2 breakpoint1.31.73.71.61.6-1.91.4-1.91.91.7-1.21.2-1.20.6-1.10.91.5-0.10.10.00.3
Progressive ratio test 2 inactive lever presses0.10.30.90.20.2-0.2-0.1-0.10.1-0.10.20.9-0.9-0.9-0.70.90.80.4-0.40.50.5
Incentive Sensitization - Responses0.30.92.31.21.2-1.31.3-1.41.41.5-1.20.2-0.30.7-0.2-0.30.3-0.90.9-0.7-0.5
Incentive Sensitization - Breakpoint0.41.02.41.21.2-1.31.3-1.51.51.6-1.30.3-0.30.7-0.2-0.20.3-0.90.9-0.7-0.5
Sum of active levers in priming session hrs 5-60.20.20.6-0.3-0.3-0.00.2-0.20.20.3-0.3-0.80.80.40.8-0.7-0.4-0.50.5-0.5-0.4
Progressive ratio1.13.110.1-0.4-0.4-0.9-0.9-0.60.6-0.21.21.9-1.80.2-1.72.13.22.6-2.62.62.7
Food seeking constrained by brief footshock0.00.00.20.50.50.10.00.2-0.2-0.2-0.00.00.00.0-0.1-0.10.0-0.10.1-0.1-0.1
Seeking ratio, punishment vs. effort1.02.37.90.50.50.80.80.6-0.60.1-1.0-1.61.5-0.51.3-1.8-2.8-2.22.2-2.2-2.4
Retroperitoneal fat weight0.31.42.8-0.5-0.50.4-1.10.7-0.7-1.21.31.1-1.0-1.0-1.01.41.71.6-1.61.61.6
Reaction time number correct0.41.63.81.81.8-1.50.9-1.21.20.8-0.81.9-1.90.4-1.71.20.90.7-0.70.50.6
Reaction time mean minus median0.95.813.2-3.6-3.63.2-2.62.9-2.9-2.52.4-2.92.9-1.72.9-1.6-1.0-0.00.00.1-0.2
Reaction time mean minus median AUC0.64.18.6-2.9-2.92.8-2.22.6-2.7-2.32.0-2.22.2-1.82.3-1.3-1.0-0.00.00.0-0.3
Reaction time num false alarms0.10.20.5-0.6-0.60.6-0.60.7-0.7-0.70.6-0.10.1-0.50.2-0.0-0.70.3-0.30.30.2
Reaction time num false alarms AUC0.20.40.8-0.7-0.70.8-0.80.9-0.9-0.90.7-0.30.3-0.70.4-0.1-0.60.4-0.40.30.2
Reaction time trials correct on left0.41.63.81.81.8-1.50.9-1.21.20.8-0.81.9-1.90.4-1.71.20.90.7-0.70.50.6
Reaction time trials on left0.41.43.41.71.7-1.40.8-1.11.10.7-0.71.9-1.80.3-1.61.10.90.8-0.80.50.7
Reaction time mean2.96.511.7-3.4-3.43.4-2.23.0-3.0-2.41.9-3.43.4-2.03.3-2.2-1.8-0.80.8-0.6-1.0
Reaction time mean AUC2.76.511.7-3.4-3.43.4-2.43.1-3.2-2.62.1-3.33.3-2.23.2-2.0-1.6-0.60.6-0.4-0.8
Median of all reaction times2.84.48.6-2.7-2.72.7-1.72.5-2.5-1.91.4-2.92.9-1.72.8-1.9-1.6-0.90.9-0.7-1.0
Reaction time omissions2.13.47.5-2.7-2.72.4-2.02.0-2.0-1.71.9-2.42.5-0.92.4-1.4-0.30.2-0.20.20.0
Reaction time false alarm rate1.11.53.0-1.7-1.71.7-1.31.6-1.6-1.41.1-1.31.3-1.01.3-0.8-1.1-0.10.1-0.0-0.2
Reaction time premature initiation rate0.30.51.6-0.3-0.30.1-0.60.2-0.2-0.50.70.3-0.1-0.6-0.30.80.91.3-1.31.01.0
Reaction time premature initiations0.41.23.10.80.8-0.8-0.1-0.50.5-0.10.31.4-1.2-0.4-1.31.51.41.8-1.81.41.5
Std. dev. reaction times2.16.814.3-3.8-3.83.6-2.93.3-3.3-2.82.6-3.13.2-2.23.0-1.5-0.90.0-0.00.2-0.2
Reaction time trials completed0.41.43.41.71.7-1.40.8-1.11.10.7-0.71.9-1.80.3-1.61.10.90.8-0.80.50.7
Reaction time trials AUC0.41.43.41.71.7-1.40.9-1.21.20.8-0.71.9-1.80.4-1.61.10.90.7-0.70.50.6
Run reversals in cocaine runway, females0.30.41.01.01.0-0.40.8-0.20.20.3-0.80.4-0.40.2-0.4-0.2-0.6-0.70.7-0.7-0.7
Run reversals in cocaine runway, males3.23.56.7-2.6-2.62.4-2.52.4-2.4-2.42.4-1.41.6-1.81.20.1-0.11.3-1.31.21.0
Latency to leave start box in cocaine runway0.10.10.20.50.5-0.30.0-0.40.40.30.00.5-0.5-0.2-0.30.20.30.2-0.20.20.3
Latency to leave start box in cocaine runway, F0.20.20.90.20.20.30.10.2-0.2-0.0-0.2-0.30.2-0.20.5-0.9-0.6-0.60.6-0.7-0.7
Latency to leave start box in cocaine runway, M1.41.33.10.40.4-0.7-0.4-0.70.70.20.61.5-1.4-0.4-1.31.71.51.5-1.51.61.7
Std. dev. time between licks in bursts1.73.16.2-2.4-2.42.5-2.12.3-2.3-2.02.0-2.02.0-1.41.9-1.3-0.30.3-0.30.30.1
Total sessions with >9 infusions0.50.61.40.60.6-0.90.3-0.80.80.4-0.11.2-1.1-0.6-1.11.10.80.7-0.70.80.9
Short access day 1 total inactive lever presses0.81.53.5-1.9-1.91.3-1.61.4-1.4-1.51.6-0.20.2-1.60.20.70.51.0-1.01.11.0
Short access day 10 total inactive lever presses0.21.33.1-0.5-0.50.40.50.1-0.10.5-0.6-1.21.01.01.2-1.7-1.7-1.81.8-1.6-1.6
Short access day 1 total infusions0.00.10.50.30.3-0.20.3-0.10.1-0.0-0.30.4-0.5-0.7-0.40.2-0.1-0.20.2-0.1-0.1
Short access day 10 total infusions0.30.51.40.70.7-0.80.3-0.60.60.3-0.21.2-1.1-0.6-1.11.10.30.5-0.50.60.7
Short access total infusions0.40.61.60.60.6-0.70.2-0.40.40.1-0.11.2-1.2-0.9-1.21.20.80.7-0.70.70.8
Short access day 1 locomotion0.30.51.30.70.7-0.40.8-0.40.40.6-0.90.2-0.30.1-0.1-0.5-1.1-1.01.0-0.9-0.9
Short access day 10 total locomotion0.31.12.1-1.3-1.31.2-1.41.3-1.3-1.41.4-0.30.4-1.40.30.4-0.20.8-0.80.90.8
Short access total locomotion0.10.20.9-0.3-0.30.1-0.40.1-0.1-0.30.40.4-0.3-1.0-0.30.5-0.30.4-0.40.50.5
One hour access (0.3 mA shock)0.80.92.50.90.9-0.61.2-0.70.71.1-1.3-0.30.10.50.2-0.9-0.3-1.61.6-1.3-1.3
Compulsive drug intake1.92.87.7-0.2-0.20.30.8-0.40.41.2-1.0-2.12.02.22.1-2.5-2.8-2.02.0-2.1-2.0
One hour access (shock baseline)0.30.73.60.20.2-0.2-0.10.2-0.2-0.50.20.9-0.9-1.8-1.01.11.90.5-0.50.70.6
Social response proportion0.40.50.8-0.9-0.90.9-0.60.9-0.9-0.70.5-0.80.8-0.90.6-0.70.4-0.40.4-0.1-0.3
Social responses0.10.22.1-0.5-0.50.1-0.30.1-0.1-0.10.3-0.0-0.0-0.2-0.1-0.01.50.0-0.00.30.3
Social time1.82.87.8-2.8-2.81.9-1.61.4-1.4-0.91.5-2.52.50.12.4-1.6-0.3-0.50.5-0.1-0.2
Soleus weight3.08.816.9-3.7-3.74.1-3.34.0-4.0-3.53.0-3.53.7-2.83.3-1.8-1.40.5-0.50.3-0.2
Bone: stiffness0.30.51.20.60.6-0.80.4-0.70.70.5-0.31.0-1.10.9-0.90.90.70.4-0.40.40.5
Tibialis anterior weight0.30.92.81.71.7-1.31.2-1.11.10.9-1.10.8-0.70.2-1.00.6-0.60.0-0.0-0.2-0.1
Time to tail flick, vehicle, before self-admin0.60.82.1-1.1-1.10.00.2-0.50.40.8-0.3-1.21.11.31.4-1.20.0-1.01.0-0.8-0.8
Time to tail flick, vehicle, after self-admin0.30.53.1-0.2-0.20.30.1-0.10.10.4-0.2-0.90.81.80.7-1.0-1.1-0.80.8-0.7-0.7
Time to tail flick, test, before self-admin0.10.10.70.40.4-0.30.2-0.30.30.3-0.20.4-0.40.8-0.40.00.2-0.10.10.00.1
Time to tail flick, test, after self-admin0.50.52.4-1.6-1.60.3-0.1-0.0-0.00.20.1-0.70.60.70.9-0.8-0.8-0.50.5-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.40.42.01.41.4-0.40.4-0.20.20.1-0.40.7-0.60.1-0.90.4-1.10.1-0.1-0.0-0.0
Delta time to tail flick, test, before/after SA0.30.30.6-0.2-0.2-0.50.7-0.60.60.8-0.7-0.40.30.60.5-0.5-0.7-0.70.7-0.7-0.6
Tibia length2.26.212.3-3.5-3.52.7-3.52.7-2.7-3.03.5-0.80.9-2.20.90.81.62.4-2.42.52.2
Ambulatory time before self-admin0.20.51.6-1.3-1.30.7-0.50.6-0.6-0.40.4-1.00.9-0.50.9-0.50.8-0.40.4-0.2-0.3
Ambulatory time after self-admin0.61.03.9-2.0-2.00.7-1.00.6-0.6-0.61.0-1.11.10.01.00.11.40.7-0.70.70.6
Bone: tissue strength0.30.31.0-0.1-0.1-0.0-0.40.1-0.1-0.40.50.5-0.4-0.3-0.50.81.00.6-0.60.80.8
Total heroin consumption0.40.41.4-1.0-1.00.5-0.20.3-0.3-0.10.2-1.21.10.31.0-1.00.1-0.50.5-0.4-0.4
Bone: trabecular number0.81.43.01.71.7-1.11.7-1.01.01.2-1.70.2-0.30.9-0.4-0.3-1.4-1.21.2-1.3-1.3
Bone: trabecular spacing1.82.75.0-1.7-1.71.1-2.11.2-1.2-1.72.20.5-0.4-1.4-0.41.31.82.1-2.12.22.1
Bone: trabecular thickness0.81.22.21.31.3-0.71.4-0.70.71.0-1.5-0.30.20.70.2-0.8-1.1-1.41.4-1.5-1.5
Bone: trabecular tissue density0.61.02.20.10.10.1-0.70.5-0.5-0.80.81.3-1.2-1.2-1.11.51.51.1-1.11.21.2
Water consumed over 24 hours0.00.10.2-0.2-0.20.2-0.30.1-0.1-0.00.3-0.30.40.10.3-0.20.10.3-0.30.20.2
Number of responses in last shaping day0.60.82.1-0.7-0.70.9-0.91.3-1.2-1.50.90.4-0.4-1.1-0.31.00.40.8-0.80.70.5