Hub : Genes

Zfp568

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Zfp568 0.41 0.2 1.4e-03 0.03 -0.01 0 0 1.0e-01 4.3e-01 3.0e-01 2.7e-01
2 Adipose alternative TSS NM_001419981.1 0.11 0.11 1.8e-08 0.05 0.05 0.05 0.04 1.2e-06 2.2e-06 4.2e-06 1.6e-05
3 Adipose alternative TSS XM_039093718.2 0.11 0.11 3.2e-08 0.05 0.05 0.05 0.04 1.9e-06 3.3e-06 5.7e-06 2.2e-05
4 Adipose gene expression Zfp568 0.06 0.05 3.4e-05 0.02 0.01 0.02 0.02 2.9e-03 7.4e-03 3.9e-03 5.5e-03
5 Adipose mRNA stability Zfp568 0.03 0.03 1.1e-03 0.01 0.01 0.01 0.01 8.5e-03 1.4e-02 1.8e-02 2.6e-02
6 pVTA mRNA stability Zfp568 0.08 0.05 3.6e-07 0.05 0.05 0.06 0.04 3.9e-05 1.3e-04 1.9e-05 2.3e-04
7 Adipose isoform ratio XM_039093718.2 0.12 0.12 9.5e-08 0.03 0.04 0.04 0.04 2.5e-04 1.0e-05 1.2e-05 5.7e-05
8 Adipose isoform ratio NM_001419981.1 0.11 0.11 1.3e-07 0.03 0.04 0.04 0.04 2.8e-04 1.2e-05 1.8e-05 8.8e-05
9 NAcc gene expression Zfp568 0.06 0.04 3.7e-14 0.1 0.09 0.09 0.09 3.6e-14 1.6e-13 4.2e-13 1.0e-13
10 OFC gene expression Zfp568 0.82 0.09 1.7e-16 0.39 0.3 0.38 0.25 2.4e-10 6.6e-08 7.1e-10 1.4e-06
11 Liver mRNA stability Zfp568 0.04 0.04 4.3e-04 0.02 0.02 0.02 0.02 1.8e-03 1.5e-03 6.5e-03 4.2e-03
12 PL gene expression Zfp568 0.36 0.13 0.0e+00 0.42 0.44 0.44 0.44 2.2e-49 3.1e-53 1.8e-52 1.1e-52
13 Brain mRNA stability Zfp568 0.23 0.09 0.0e+00 0.4 0.39 0.4 0.4 8.0e-40 4.0e-38 1.9e-39 6.9e-40
14 NAcc mRNA stability Zfp568 0.07 0.05 1.5e-08 0.05 0.06 0.05 0.05 2.4e-08 8.3e-09 5.5e-08 1.8e-08
15 LHb gene expression Zfp568 0.71 0.14 7.7e-15 0.4 0.13 0.42 0.17 2.1e-10 5.2e-04 3.9e-11 8.6e-05
16 BLA gene expression Zfp568 0.31 0.14 1.1e-16 0.27 0.27 0.28 0.27 8.2e-15 1.1e-14 7.1e-15 8.9e-15
17 IC gene expression Zfp568 0.15 0.09 4.0e-06 0.07 0.07 0.07 0.04 8.4e-04 6.1e-04 6.8e-04 6.3e-03
18 Liver gene expression Zfp568 0.16 0.11 0.0e+00 0.11 0.11 0.1 0.11 1.7e-12 2.1e-12 1.5e-11 7.5e-12
19 PL mRNA stability Zfp568 0.23 0.12 2.5e-07 0.06 0.07 0.06 0.05 2.2e-07 3.5e-08 6.5e-07 1.3e-06
20 Eye mRNA stability Zfp568 0.48 0.19 6.9e-05 0.18 0.02 0.21 0.08 1.0e-03 1.4e-01 3.6e-04 2.3e-02
21 IL gene expression Zfp568 0.73 0.1 0.0e+00 0.5 0.1 0.52 0.12 5.5e-14 2.7e-03 1.9e-14 1.0e-03
22 Brain gene expression Zfp568 0.37 0.04 0.0e+00 0.58 0.06 0.6 0.21 9.3e-67 3.6e-06 2.3e-70 1.6e-19
23 pVTA gene expression Zfp568 0.14 0.09 1.2e-07 0.08 0.06 0.07 0.04 5.0e-07 8.0e-06 1.5e-06 5.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.30.61.51.2-0.10.1-0.1-0.1-0.60.6-0.61.11.0-0.60.6-0.8-0.61.10.80.80.6-0.3-1.21.10.80.4
Area under the delay curve1.01.12.10.9-1.31.3-1.3-1.3-1.11.1-1.10.70.6-1.01.1-1.0-1.20.81.00.91.2-1.5-0.90.80.91.1
BMI with tail0.10.20.3-0.30.5-0.50.50.50.5-0.50.5-0.4-0.40.6-0.50.30.5-0.5-0.4-0.5-0.30.10.3-0.3-0.4-0.3
BMI without tail0.51.62.50.9-1.41.4-1.4-1.4-1.31.2-1.21.01.0-1.01.1-1.3-1.31.01.21.11.6-1.4-1.01.31.31.5
Body weight2.812.315.73.9-3.33.3-3.3-3.3-3.43.5-3.53.94.0-3.63.4-3.5-3.33.83.53.63.3-2.6-3.83.83.43.3
Weight adjusted by age0.10.11.30.40.1-0.10.10.10.4-0.20.2-0.1-0.30.1-0.30.30.5-0.3-0.3-0.2-0.21.1-0.10.1-0.4-0.5
Bone surface1.12.03.31.7-0.90.9-0.9-0.9-1.51.5-1.41.81.7-1.41.4-1.5-1.51.61.61.51.1-1.4-1.81.61.61.2
Bone volume1.11.93.31.8-1.01.0-1.0-1.0-1.41.4-1.41.71.6-1.41.4-1.4-1.41.51.51.51.1-1.0-1.81.61.51.1
Breakpoint value in progressive ratio session2.42.84.51.0-2.02.0-2.0-2.0-1.81.7-1.71.21.5-1.61.7-1.8-1.81.41.61.61.8-2.1-1.41.21.61.6
Number of licking bursts3.15.15.9-1.72.2-2.22.22.22.3-2.22.2-2.3-2.32.2-2.32.42.4-2.4-2.3-2.3-2.32.12.1-2.4-2.4-2.3
Context. condit. distance diff. score0.00.00.10.2-0.10.1-0.1-0.10.10.0-0.0-0.2-0.20.0-0.10.00.0-0.40.0-0.1-0.10.10.1-0.1-0.10.0
Locomotion velocity, session 10.60.71.3-0.81.1-1.11.11.10.8-0.90.9-0.7-0.70.9-0.80.80.8-0.7-0.6-0.8-0.80.80.6-0.5-0.6-0.7
Locomotion distance, session 10.50.60.90.7-0.70.7-0.7-0.7-0.80.8-0.80.90.9-0.80.8-0.8-0.80.70.80.80.7-0.8-0.80.70.90.9
Locomotion velocity, session 20.30.41.2-1.10.5-0.50.50.50.6-0.70.7-0.5-0.50.8-0.70.60.5-0.5-0.6-0.7-0.40.40.9-0.4-0.6-0.6
Locomotion distance, session 21.41.92.5-1.61.6-1.61.61.61.3-1.41.4-1.3-1.31.5-1.41.31.4-1.4-1.3-1.4-1.20.81.4-1.4-1.3-1.3
Locomotion velocity, session 30.40.40.8-0.40.6-0.60.60.60.7-0.60.6-0.7-0.70.6-0.70.60.7-0.7-0.6-0.6-0.60.90.7-0.5-0.7-0.5
Locomotion distance, session 33.43.74.81.6-2.12.1-2.1-2.1-1.92.1-2.11.71.7-2.01.9-2.0-1.91.51.91.92.1-2.2-1.61.71.72.2
Stereotopy head waving bouts, day 30.70.81.4-0.71.2-1.21.21.20.9-1.01.0-0.6-0.60.9-0.90.90.8-0.3-0.8-0.8-1.20.90.7-0.8-0.7-0.9
Stereotopy head waving duration, day 31.61.92.8-1.11.6-1.61.61.61.4-1.51.5-1.2-1.21.5-1.51.41.3-0.8-1.3-1.4-1.71.41.1-1.2-1.2-1.4
Locomotion velocity, session 70.30.30.50.7-0.40.4-0.4-0.4-0.50.6-0.60.70.7-0.50.5-0.5-0.50.50.60.60.6-0.6-0.60.50.50.5
Locomotion distance, session 70.10.10.20.3-0.30.3-0.3-0.3-0.30.4-0.40.40.4-0.40.4-0.4-0.40.20.40.40.4-0.2-0.30.40.50.3
Stereotopy head waving bouts, day 71.71.92.5-1.31.2-1.21.21.21.3-1.31.4-1.5-1.51.4-1.41.41.4-1.4-1.4-1.4-1.41.41.4-1.5-1.6-1.4
Stereotopy head waving duration, day 72.12.53.2-1.41.4-1.41.41.41.6-1.61.6-1.6-1.61.7-1.71.61.7-1.5-1.7-1.7-1.71.51.6-1.6-1.8-1.7
Locomotion velocity, session 84.04.85.6-1.92.3-2.32.32.32.2-2.22.2-2.1-2.12.2-2.22.22.1-2.2-2.1-2.2-2.31.72.2-2.2-2.3-2.4
Locomotion distance, session 80.60.91.7-0.90.9-0.90.90.91.0-0.90.9-1.0-1.01.0-1.01.01.0-1.3-0.9-1.0-0.90.71.1-1.1-1.1-0.9
Degree of sensitization distance0.80.81.7-0.61.1-1.11.11.10.9-0.90.9-0.7-0.70.9-0.90.90.8-0.7-0.8-0.8-1.01.30.6-0.6-0.6-1.1
Degree of sensitization stereotypy1.11.22.0-1.00.7-0.70.70.71.1-1.11.1-1.3-1.31.1-1.11.11.2-1.3-1.2-1.2-1.11.11.1-1.3-1.4-1.2
Conditioned locomotion0.20.31.0-1.00.2-0.20.20.20.4-0.50.5-0.7-0.70.6-0.50.50.4-0.6-0.5-0.6-0.30.30.7-0.5-0.5-0.2
Cocaine response after cond. corrected0.00.10.2-0.5-0.40.4-0.4-0.40.0-0.10.1-0.1-0.10.0-0.00.0-0.00.1-0.1-0.10.20.40.30.1-0.00.1
Cocaine response after cond. not corrected0.00.00.2-0.4-0.20.2-0.2-0.2-0.0-0.10.10.10.1-0.00.0-0.1-0.10.20.00.00.20.30.20.30.10.2
Cocaine response before conditioning0.91.11.71.2-0.40.4-0.4-0.4-1.01.0-1.01.31.3-1.01.0-1.1-1.01.21.21.10.8-1.1-1.31.31.21.0
Saline control response0.00.00.3-0.6-0.20.2-0.2-0.20.0-0.10.1-0.2-0.20.1-0.10.00.1-0.2-0.1-0.20.10.20.3-0.0-0.1-0.4
Bone: connectivity density0.10.20.70.70.2-0.20.20.2-0.40.4-0.40.80.8-0.40.3-0.4-0.40.80.50.50.1-0.5-0.70.50.50.2
Bone: cortical apparent density2.12.93.9-1.62.0-2.02.02.01.7-1.71.7-1.8-1.71.7-1.71.71.7-1.8-1.5-1.6-1.71.41.5-1.6-1.5-1.5
Bone: cortical area1.72.63.11.6-1.71.7-1.7-1.7-1.71.6-1.61.61.5-1.61.6-1.6-1.71.51.71.61.4-1.1-1.51.81.61.5
Bone: cortical porosity1.21.32.1-0.81.3-1.31.31.31.2-1.01.0-0.9-0.91.1-1.21.21.2-0.9-1.2-1.1-1.40.41.0-1.4-1.2-1.4
Bone: cortical porosity1.82.02.9-1.21.6-1.61.61.61.5-1.31.3-1.1-1.21.4-1.51.41.4-1.2-1.4-1.4-1.70.61.3-1.7-1.5-1.7
Bone: cortical thickness0.61.01.51.1-1.21.2-1.2-1.2-1.11.0-1.00.90.9-1.01.0-1.0-1.10.91.01.00.8-0.5-0.91.11.11.0
Bone: cortical thickness0.60.71.1-0.90.7-0.70.70.70.9-0.90.9-0.9-0.90.9-0.90.90.8-0.8-0.8-0.9-1.01.00.9-0.8-0.8-0.8
Bone: cortical tissue density2.43.24.4-1.72.1-2.12.12.11.8-1.81.8-1.9-1.81.8-1.81.81.8-1.9-1.6-1.7-1.81.41.6-1.7-1.6-1.6
Condit. Reinf. active minus inactive responses0.20.20.3-0.30.5-0.50.50.50.4-0.40.4-0.6-0.60.5-0.40.40.4-0.5-0.3-0.5-0.10.10.4-0.2-0.3-0.2
Condit. Reinf. active-inactive response ratio0.10.10.2-0.00.3-0.30.30.30.3-0.40.4-0.4-0.40.4-0.30.30.2-0.1-0.3-0.3-0.00.10.3-0.1-0.2-0.2
Condit. Reinf. active responses1.92.43.0-1.61.7-1.71.71.71.4-1.61.6-1.7-1.71.7-1.61.51.5-1.7-1.4-1.6-1.30.81.6-1.5-1.4-1.2
Condit. Reinf. inactive responses2.12.63.9-2.01.7-1.71.71.71.5-1.51.5-1.7-1.71.7-1.61.61.6-1.9-1.5-1.7-1.50.81.7-1.8-1.5-1.3
Incentive salience index mean0.10.10.2-0.30.4-0.40.40.40.2-0.40.4-0.5-0.50.4-0.40.30.3-0.5-0.2-0.40.1-0.10.4-0.1-0.3-0.1
Condit. Reinf. lever presses0.00.10.5-0.00.0-0.00.00.0-0.20.1-0.10.10.1-0.00.1-0.2-0.10.00.20.00.4-0.70.00.30.20.4
Condit. Reinf. active minus inactive responses2.22.84.41.2-2.12.1-2.1-2.1-1.81.7-1.71.51.4-1.61.7-1.7-1.71.51.71.61.8-1.6-1.21.71.61.6
Condit. Reinf. active-inactive response ratio0.10.10.5-0.2-0.70.7-0.7-0.7-0.10.0-0.0-0.3-0.4-0.00.1-0.1-0.1-0.3-0.0-0.10.20.40.40.0-0.1-0.0
Condit. Reinf. active responses4.36.06.62.2-2.62.6-2.6-2.6-2.52.5-2.52.52.4-2.42.5-2.5-2.52.32.52.42.6-2.5-2.12.52.42.4
Condit. Reinf. inactive responses4.35.69.12.2-2.12.1-2.1-2.1-2.42.5-2.42.72.6-2.42.4-2.4-2.42.42.42.42.2-3.0-2.32.12.32.4
Condit. Reinf. lever presses9.112.613.73.6-3.73.7-3.7-3.7-3.63.6-3.63.53.4-3.63.6-3.6-3.63.53.63.53.5-3.4-3.33.53.53.4
Condit. Reinf. lever reinforcers received4.66.57.32.4-2.72.7-2.7-2.7-2.62.6-2.62.52.4-2.52.6-2.6-2.62.32.62.52.6-2.5-2.22.52.52.4
Conditioned reinforcement - actives0.61.02.3-1.10.7-0.70.70.71.0-1.01.0-1.2-1.01.0-1.01.10.9-1.1-1.0-1.0-1.21.50.9-1.0-1.0-1.0
Conditioned reinforcement - inactives0.20.31.00.2-0.70.7-0.7-0.7-0.60.6-0.60.50.6-0.50.5-0.4-0.50.50.50.40.3-1.0-0.20.10.20.4
Conditioned locomotion2.53.33.9-1.92.0-2.02.02.01.8-1.81.8-1.7-1.71.9-1.91.81.7-1.7-1.8-1.8-1.91.51.7-1.9-1.7-1.8
Patch foraging indifference point 0 sec0.10.10.60.2-0.40.4-0.4-0.4-0.30.4-0.40.50.2-0.40.4-0.3-0.40.20.30.40.2-0.8-0.20.10.30.3
Patch foraging indifference point AUC0.60.81.4-0.80.7-0.70.70.70.9-1.01.0-0.7-0.91.0-1.01.00.9-0.7-1.0-1.0-1.20.91.1-0.9-1.0-1.1
Delay disc. indifference point, 0s delay0.70.81.70.1-1.31.3-1.3-1.3-1.00.9-0.90.40.3-0.70.9-0.8-1.00.01.00.61.0-0.9-0.80.60.81.0
Delay disc. indifference point, 16s delay2.12.34.81.0-1.91.9-1.9-1.9-1.71.5-1.50.60.5-1.41.6-1.4-1.80.81.51.41.8-2.2-1.11.21.41.6
Delay disc. indifference point, 2s delay1.21.32.10.9-1.41.4-1.4-1.4-1.21.3-1.31.11.0-1.21.2-1.1-1.20.91.21.10.9-1.0-1.20.91.01.0
Delay disc. indifference point, 24s delay2.52.84.41.6-1.61.6-1.6-1.6-1.71.7-1.71.51.6-1.71.7-1.7-1.61.61.61.71.8-2.1-1.41.61.61.8
Delay disc. indifference point, 4s delay0.10.10.30.3-0.60.6-0.6-0.6-0.30.3-0.30.10.1-0.20.3-0.3-0.30.20.20.10.4-0.5-0.10.10.10.3
Delay disc. indifference point, 8s delay0.20.20.80.90.0-0.00.00.0-0.30.4-0.40.50.4-0.40.4-0.4-0.40.60.30.40.5-0.7-0.50.30.40.5
Indifference point function ln k0.30.61.00.4-0.80.8-0.8-0.8-0.80.8-0.80.30.5-0.70.8-0.8-0.80.50.80.81.0-0.9-0.70.70.90.9
Indifference point function log k0.30.61.00.4-0.80.8-0.8-0.8-0.80.8-0.80.30.5-0.70.8-0.8-0.80.50.80.81.0-0.9-0.70.70.90.9
Patch foraging total patch changes 0 sec0.10.20.80.3-0.50.5-0.5-0.5-0.40.5-0.50.70.4-0.50.5-0.4-0.50.30.40.50.4-0.9-0.30.20.40.5
Patch foraging total patch changes 12 sec0.10.10.3-0.1-0.40.4-0.4-0.4-0.30.2-0.20.30.0-0.10.2-0.1-0.40.20.20.10.2-0.50.10.10.20.3
Patch foraging total patch changes 18 sec0.20.40.7-0.20.7-0.70.70.70.7-0.50.5-0.1-0.40.5-0.60.60.6-0.5-0.6-0.5-0.90.60.5-0.7-0.7-0.7
Patch foraging total patch changes 24 sec0.40.61.11.0-0.90.9-0.9-0.9-0.80.8-0.80.90.6-0.80.8-0.7-0.70.50.80.80.6-0.2-0.80.80.50.8
Patch foraging total patch changes 6 sec0.00.00.2-0.1-0.10.1-0.1-0.10.20.00.00.50.1-0.0-0.10.10.10.2-0.20.0-0.30.00.3-0.2-0.3-0.3
Patch foraging time to switch 0 sec0.20.40.9-1.00.7-0.70.70.70.5-0.80.8-0.9-0.60.8-0.70.60.4-0.6-0.5-0.7-0.20.40.8-0.3-0.4-0.2
Patch foraging water rate 0 sec0.61.42.3-0.91.2-1.21.21.21.3-1.01.0-0.7-0.91.0-1.11.21.3-1.0-1.2-1.0-1.50.91.2-1.4-1.3-1.5
Patch foraging water rate 12 sec0.20.51.61.3-1.01.0-1.0-1.0-0.50.8-0.80.70.6-0.90.6-0.5-0.30.60.50.70.30.3-0.80.50.20.3
Patch foraging water rate 18 sec0.20.20.9-0.20.3-0.30.30.30.5-0.30.3-0.3-0.40.3-0.40.50.6-0.2-0.6-0.4-0.80.50.3-0.8-0.6-0.9
Patch foraging water rate 24 sec0.00.10.4-0.0-0.20.2-0.2-0.20.10.1-0.1-0.1-0.2-0.1-0.00.20.2-0.3-0.2-0.1-0.4-0.00.0-0.6-0.4-0.6
Patch foraging water rate 6 sec0.50.71.61.2-0.60.6-0.6-0.6-0.61.0-1.01.21.2-1.00.8-0.8-0.51.00.70.90.4-0.6-1.10.60.50.3
Seeking ratio, delayed vs. immediate footshock1.31.62.11.3-1.41.4-1.4-1.4-1.31.4-1.30.90.9-1.31.3-1.3-1.40.71.31.21.4-1.0-1.41.21.11.2
Distance traveled before self-admin0.81.02.2-0.1-1.51.5-1.5-1.5-1.30.9-0.90.50.6-0.81.1-0.8-1.30.51.10.80.8-1.3-0.60.70.90.7
Distance traveled after self-admin2.22.73.51.7-1.41.4-1.4-1.4-1.81.7-1.71.81.9-1.71.7-1.6-1.71.91.71.71.4-1.7-1.71.51.61.5
Extensor digitorum longus weight0.20.82.2-0.70.9-0.90.90.90.9-1.01.0-0.8-0.70.9-0.90.80.9-0.6-0.8-0.9-0.91.50.7-0.4-0.8-0.9
Bone: elastic displacement0.00.00.1-0.0-0.20.2-0.2-0.20.0-0.00.0-0.1-0.1-0.00.00.1-0.0-0.0-0.10.0-0.30.2-0.1-0.10.0-0.0
Bone: elastic work2.02.63.21.6-1.81.8-1.8-1.8-1.61.6-1.61.51.4-1.61.6-1.6-1.71.51.61.61.4-1.2-1.71.61.61.5
Bone: endosteal estimation1.63.54.41.8-1.71.7-1.7-1.7-2.01.9-1.92.12.0-1.91.9-1.9-1.92.02.01.91.7-2.0-1.91.92.01.7
Bone: endosteal perimeter1.63.33.81.5-1.91.9-1.9-1.9-2.01.9-1.91.71.7-1.81.9-1.9-1.91.61.91.81.9-2.0-1.61.91.81.9
Epididymis fat weight0.00.20.50.20.7-0.70.70.70.3-0.30.3-0.1-0.00.3-0.30.20.4-0.0-0.2-0.2-0.40.4-0.2-0.0-0.3-0.5
Delta time in closed arm before/after self-admin0.80.71.71.3-0.60.6-0.6-0.6-0.70.9-0.91.01.2-0.90.8-0.8-0.71.10.80.90.6-0.7-1.10.90.60.6
Delta time in open arm before/after self-admin0.60.61.5-1.00.6-0.60.60.60.8-0.80.8-0.4-0.40.7-0.80.71.0-0.5-1.0-0.8-0.61.20.9-0.7-0.8-0.8
Diff in mean of infusions in LGA sessions0.10.11.1-1.1-0.10.1-0.1-0.10.0-0.20.2-0.4-0.20.3-0.10.10.0-0.3-0.2-0.30.0-0.80.6-0.7-0.2-0.1
Delay discount exponential model param1.01.22.1-1.11.3-1.31.31.31.1-1.11.1-0.8-0.71.0-1.11.01.1-0.9-1.0-1.0-1.21.40.9-0.8-0.9-1.1
Extinction: sum of active levers before priming3.53.85.82.1-1.31.3-1.3-1.3-2.01.9-1.91.81.9-1.91.9-2.1-2.01.92.12.02.4-1.9-2.22.22.42.3
Active lever presses in extinction session 61.91.93.11.1-1.21.2-1.2-1.2-1.51.3-1.31.31.5-1.31.4-1.4-1.51.71.51.41.4-1.4-1.31.61.81.4
Bone: final force1.72.74.12.0-1.41.4-1.4-1.4-1.71.7-1.71.81.8-1.71.7-1.7-1.71.71.71.71.5-1.6-1.81.71.71.4
Bone: final moment2.33.74.82.2-1.71.7-1.7-1.7-1.92.0-1.92.02.0-2.02.0-2.0-2.02.02.02.01.8-1.7-2.02.02.01.7
Food consumed during 24 hour testing period0.60.92.11.2-0.80.8-0.8-0.8-0.91.0-1.00.90.9-0.90.9-0.9-1.00.90.90.90.8-1.4-0.90.70.80.8
Glucose0.30.51.0-0.20.7-0.70.70.70.7-0.70.7-0.6-0.70.6-0.60.70.7-0.5-0.7-0.7-0.81.00.5-0.7-0.6-0.8
Heart weight0.10.20.70.4-0.80.8-0.8-0.8-0.30.5-0.50.30.4-0.40.3-0.3-0.30.50.20.30.4-0.0-0.20.40.10.4
Delay discount hyperbolic model param0.80.81.5-0.91.1-1.11.11.11.0-0.90.9-0.6-0.60.9-1.00.91.0-0.7-0.8-0.8-1.01.20.8-0.6-0.8-0.9
Intermittent access intake day 1-15 change0.81.62.61.6-1.31.3-1.3-1.3-1.01.3-1.31.51.5-1.41.1-1.2-1.01.31.11.31.10.0-1.51.41.00.9
Intermittent access intake escalation0.40.91.81.3-0.90.9-0.9-0.9-0.71.0-1.01.21.3-1.10.8-0.9-0.71.00.81.10.80.3-1.31.10.70.6
Intermittent access intake escalation 21.41.62.31.4-1.51.5-1.5-1.5-1.21.2-1.21.21.3-1.31.3-1.2-1.21.21.21.31.2-0.6-1.21.31.21.1
Intermitt. access day 1 inactive lever presses1.97.315.52.5-2.22.2-2.2-2.2-2.82.7-2.72.72.8-2.62.7-2.8-2.82.82.72.63.0-3.9-2.42.52.83.0
Intermitt. access day 15 inactive lever presses0.71.54.71.2-1.11.1-1.1-1.1-1.21.3-1.31.11.2-1.21.2-1.2-1.11.11.11.21.4-2.2-0.90.81.11.3
Intermitt. access escalation Index0.10.10.4-0.6-0.10.1-0.1-0.10.1-0.10.1-0.4-0.40.2-0.10.20.1-0.5-0.2-0.2-0.20.10.3-0.6-0.3-0.3
Intermittent access day 1 total infusions1.32.04.3-1.81.1-1.11.11.11.2-1.31.3-1.9-1.81.5-1.31.41.2-2.1-1.3-1.5-1.31.21.4-1.7-1.3-1.2
Intermittent access day 15 total infusions0.10.10.7-0.4-0.30.3-0.3-0.30.1-0.00.0-0.6-0.50.1-0.10.20.0-0.8-0.2-0.2-0.10.8-0.0-0.3-0.2-0.2
Intermittent access terminal intake (last 3 days)0.20.20.9-0.7-0.50.5-0.5-0.50.0-0.10.1-0.8-0.70.2-0.20.30.1-1.0-0.3-0.3-0.10.50.3-0.7-0.3-0.2
Intermittent access total infusions0.50.62.0-1.00.3-0.30.30.30.5-0.60.6-1.2-1.20.7-0.60.70.5-1.4-0.6-0.7-0.60.80.6-1.0-0.7-0.6
Intermittent access day 1 locomotion0.40.61.6-1.30.5-0.50.50.50.5-0.60.6-1.0-1.00.8-0.70.70.5-1.2-0.6-0.8-0.6-0.10.9-1.1-0.6-0.5
Intermittent access day 15 total locomotion0.00.00.2-0.30.2-0.20.20.20.20.0-0.0-0.0-0.00.1-0.20.10.1-0.4-0.1-0.1-0.20.00.0-0.4-0.2-0.2
Intermittent access total locomotion0.91.11.9-1.40.9-0.90.90.90.9-1.01.0-1.1-1.11.1-1.01.00.9-1.3-1.0-1.1-1.00.61.1-1.2-1.0-0.9
Intermittent access standard deviation2.45.15.72.2-2.42.4-2.4-2.4-2.32.4-2.42.02.1-2.32.3-2.2-2.41.92.32.32.2-2.1-2.32.12.22.2
Left kidney weight1.46.710.93.3-2.22.2-2.2-2.2-2.42.6-2.63.02.9-2.82.5-2.7-2.32.82.62.82.4-1.2-3.23.02.52.3
Right kidney weight2.19.713.53.6-2.72.7-2.7-2.7-3.13.1-3.13.23.3-3.23.1-3.2-3.03.33.23.33.1-2.0-3.73.63.23.1
Cocaine induced anxiety0.00.00.0-0.0-0.10.1-0.1-0.1-0.10.0-0.10.10.1-0.10.1-0.1-0.10.20.10.10.2-0.1-0.10.10.10.1
Post-drug Anxiety0.10.10.7-0.1-0.50.5-0.5-0.5-0.40.2-0.2-0.1-0.2-0.20.3-0.2-0.40.10.30.10.3-0.80.10.10.20.3
Baseline Anxiety0.10.10.70.4-0.20.2-0.2-0.2-0.30.3-0.30.0-0.1-0.20.3-0.2-0.30.00.30.20.1-0.8-0.00.10.20.2
Tail length5.220.321.84.7-4.74.7-4.7-4.7-4.54.6-4.64.54.5-4.74.6-4.5-4.54.54.54.64.5-3.5-4.54.64.44.3
Length with tail6.930.234.95.8-5.65.6-5.6-5.6-5.55.6-5.65.95.9-5.75.5-5.5-5.35.95.45.65.1-4.2-5.65.55.25.0
Length without tail2.68.312.63.4-2.72.7-2.7-2.7-2.73.0-2.93.53.5-3.12.8-2.8-2.53.52.73.02.4-1.8-3.22.82.62.4
Times rat made contact with spout1.21.43.1-0.11.3-1.31.31.31.3-1.21.2-1.1-1.21.1-1.11.31.1-1.1-1.1-1.1-1.51.80.7-1.0-1.0-1.2
Lifetime Intake0.80.92.3-1.20.6-0.60.60.60.8-0.80.8-1.3-1.30.9-0.90.90.8-1.5-0.9-0.9-0.91.20.8-1.2-0.9-0.8
Liver weight, left0.50.91.3-0.80.7-0.70.70.71.0-1.01.0-1.1-1.10.9-0.91.01.0-1.0-1.1-0.9-0.91.11.0-1.2-0.9-1.0
Liver weight, right0.20.40.7-0.80.2-0.20.20.20.5-0.60.6-0.8-0.80.5-0.50.60.6-0.6-0.7-0.6-0.60.50.8-0.8-0.6-0.6
Locomotor activity0.60.91.6-0.81.3-1.31.31.31.0-1.01.0-0.8-0.80.9-0.90.90.9-0.6-0.8-0.9-1.00.70.8-0.7-0.8-1.1
Locomotor testing distance0.91.62.8-1.11.7-1.71.71.71.3-1.31.3-1.0-1.01.3-1.21.11.2-1.0-1.1-1.2-1.21.20.9-0.9-1.0-1.3
Locomotor testing rearing2.14.28.5-1.92.0-2.02.02.02.1-2.12.1-1.8-1.92.0-2.12.02.2-2.0-2.0-2.0-2.12.91.8-1.7-2.1-2.2
Locomotion in novel chamber0.10.11.0-0.60.1-0.10.10.1-0.0-0.10.1-0.2-0.20.2-0.0-0.1-0.2-0.00.1-0.10.3-1.00.3-0.10.30.2
Locomotion in novel chamber post-restriction0.50.82.1-0.1-1.11.1-1.1-1.1-1.10.7-0.70.20.3-0.50.8-0.8-1.20.50.90.61.1-1.4-0.20.71.01.1
Fecal boli incidents, locomotor time 11.52.24.0-2.01.5-1.51.51.51.2-1.51.5-1.8-1.91.6-1.41.41.2-1.6-1.4-1.5-1.30.21.8-1.6-1.1-1.3
Change in fecal boli incidents, locomotor task0.10.10.60.3-0.10.1-0.1-0.10.0-0.10.10.60.6-0.0-0.0-0.00.00.8-0.10.00.10.20.10.40.10.1
Time >=10cm from walls, locomotor time 10.00.00.10.20.1-0.10.10.10.1-0.10.1-0.2-0.40.1-0.10.10.1-0.1-0.2-0.10.10.10.2-0.0-0.1-0.0
Bouts of movement, locomotor time 11.61.84.20.8-2.02.0-2.0-2.0-1.51.4-1.40.80.7-1.31.4-1.1-1.40.61.21.21.1-1.2-0.90.81.01.2
Total resting periods, locomotor time 11.71.94.20.7-2.12.1-2.1-2.1-1.51.4-1.40.80.7-1.21.4-1.1-1.50.61.31.11.2-1.4-0.90.91.11.3
Rest time, locomotor task time 10.40.51.7-1.30.2-0.20.20.20.5-0.80.8-0.9-0.90.9-0.70.70.5-0.6-0.7-0.9-0.6-0.21.2-0.9-0.6-0.5
Distance moved, locomotor task time 10.10.10.7-0.10.3-0.30.30.30.4-0.20.2-0.0-0.00.1-0.30.30.3-0.3-0.2-0.1-0.30.8-0.0-0.2-0.4-0.4
Vertical activity count, locomotor time 10.51.33.31.5-0.80.8-0.8-0.8-0.91.2-1.21.81.8-1.21.0-1.2-0.81.50.91.21.1-0.6-1.21.30.91.0
Time >=10cm from walls, locomotor time 20.50.81.8-1.20.6-0.60.60.60.7-0.80.8-1.0-1.30.9-0.80.90.7-1.0-0.9-1.0-0.70.31.3-1.1-1.0-0.9
Bouts of movement, locomotor time 20.10.20.70.2-0.80.8-0.8-0.8-0.40.3-0.3-0.10.0-0.20.3-0.1-0.40.10.20.20.10.4-0.10.20.20.1
Total resting periods, locomotor time 20.00.10.30.0-0.60.6-0.6-0.6-0.20.1-0.1-0.00.0-0.10.10.0-0.10.1-0.00.0-0.00.40.10.10.0-0.0
Rest time, locomotor task time 20.10.10.4-0.4-0.00.0-0.0-0.00.2-0.30.3-0.3-0.10.4-0.30.30.30.1-0.4-0.4-0.3-0.10.7-0.5-0.3-0.3
Distance moved, locomotor task time 20.30.41.2-0.50.6-0.60.60.60.7-0.50.5-0.3-0.60.5-0.60.60.6-0.7-0.5-0.5-0.81.10.3-0.5-0.8-0.8
Vertical activity count, locomotor time 20.40.61.10.9-0.70.7-0.7-0.7-0.70.8-0.81.01.0-0.80.7-0.8-0.60.80.70.80.7-0.4-0.80.90.60.6
Light reinforcement 10.10.30.6-0.40.3-0.30.30.30.7-0.50.5-0.2-0.50.5-0.60.60.7-0.4-0.7-0.5-0.70.80.6-0.7-0.7-0.7
Light reinforcement 22.43.74.5-1.81.9-1.91.91.92.0-2.02.0-1.7-1.82.0-2.12.02.1-1.7-2.0-2.0-2.11.51.9-1.9-1.9-2.0
Bone: marrow area1.73.74.61.8-1.71.7-1.7-1.7-2.01.9-1.92.12.1-1.92.0-1.9-2.02.02.02.01.7-2.0-1.91.92.01.7
Bone: maximum diameter1.42.73.31.6-1.71.7-1.7-1.7-1.71.7-1.71.61.6-1.71.7-1.6-1.71.51.71.71.5-1.3-1.61.81.61.6
Bone: maximum force2.95.16.42.5-2.12.1-2.1-2.1-2.32.3-2.32.32.3-2.32.3-2.3-2.32.32.32.32.1-2.0-2.42.32.32.0
Bone: maximum moment3.56.27.02.7-2.42.4-2.4-2.4-2.52.5-2.52.52.5-2.62.5-2.6-2.52.42.52.52.4-2.1-2.62.52.52.3
Mean time between licks in bursts0.00.10.1-0.3-0.30.3-0.3-0.3-0.20.3-0.30.30.3-0.20.2-0.2-0.20.30.20.20.3-0.3-0.10.30.10.3
Mean num. licks in bursts1.01.62.31.5-1.11.1-1.1-1.1-1.31.2-1.21.21.2-1.21.3-1.3-1.41.31.31.31.1-0.7-1.41.51.51.2
Cd content in liver0.40.40.8-0.10.8-0.80.80.80.7-0.60.6-0.5-0.50.5-0.60.60.7-0.5-0.6-0.5-0.90.80.3-0.5-0.7-0.8
Co content in liver0.50.50.9-0.70.9-0.90.90.90.7-0.80.8-0.4-0.40.8-0.80.70.8-0.3-0.7-0.7-0.60.60.8-0.4-0.7-0.5
Cu content in liver1.01.22.11.1-1.21.2-1.2-1.2-1.01.1-1.11.51.5-1.21.1-1.0-1.01.31.01.10.6-0.7-1.20.81.00.8
Fe content in liver0.20.30.4-0.60.6-0.60.60.60.4-0.60.6-0.5-0.50.6-0.50.50.5-0.4-0.5-0.6-0.40.20.6-0.4-0.4-0.6
K content in liver0.20.20.4-0.0-0.50.5-0.5-0.5-0.30.3-0.30.50.5-0.30.3-0.4-0.30.60.30.30.5-0.5-0.10.40.20.4
Mg content in liver0.20.20.6-0.80.2-0.20.20.20.5-0.50.5-0.3-0.30.5-0.50.50.5-0.1-0.6-0.5-0.50.40.8-0.5-0.5-0.6
Mn content in liver0.40.50.8-0.90.7-0.70.70.70.7-0.80.8-0.6-0.60.7-0.70.80.7-0.4-0.8-0.7-0.80.50.9-0.8-0.6-0.7
Na content in liver1.11.11.60.7-1.31.3-1.3-1.3-1.11.0-1.01.11.1-1.11.0-1.1-1.01.01.11.01.2-0.7-0.91.21.01.1
Rb content in liver0.10.10.2-0.30.0-0.00.00.00.2-0.20.2-0.4-0.40.2-0.20.30.2-0.4-0.2-0.2-0.1-0.00.3-0.4-0.4-0.2
Se content in liver5.46.47.4-2.52.6-2.62.62.62.6-2.72.7-2.4-2.42.6-2.62.52.5-2.1-2.6-2.6-2.52.12.7-2.4-2.3-2.5
Sr content in liver0.20.20.5-0.40.7-0.70.70.70.4-0.50.5-0.1-0.10.5-0.50.40.50.0-0.4-0.4-0.40.10.5-0.3-0.4-0.4
Zn content in liver2.83.14.2-1.42.0-2.02.02.01.9-1.91.9-1.1-1.11.8-1.91.81.9-1.0-1.9-1.8-2.01.51.7-1.7-1.8-1.9
Bone: minimum diameter4.27.69.12.3-3.03.0-3.0-3.0-2.92.8-2.82.62.6-2.82.8-2.8-2.82.42.82.72.8-2.6-2.42.82.62.5
Time in familiar zone, hab. session 10.30.30.40.7-0.50.5-0.5-0.5-0.50.5-0.50.60.6-0.60.5-0.5-0.50.70.50.60.40.1-0.50.60.60.5
Time in novel zone, hab. session 10.90.91.8-1.00.5-0.50.50.51.0-0.90.9-1.2-1.21.0-1.01.01.0-1.1-1.2-1.0-1.00.51.1-1.4-1.2-1.0
Total zone transitions, hab. session 10.00.00.2-0.2-0.20.2-0.2-0.2-0.20.1-0.1-0.0-0.0-0.00.1-0.1-0.1-0.10.10.00.4-0.30.00.10.20.3
Total locomotion distance, hab. session 11.92.74.01.0-1.91.9-1.9-1.9-1.71.6-1.61.41.4-1.61.7-1.6-1.71.51.61.51.8-2.0-1.41.31.71.7
Locomotion velocity, hab. session 11.11.62.80.7-1.31.3-1.3-1.3-1.41.2-1.21.21.2-1.21.3-1.2-1.41.21.31.21.4-1.7-1.11.11.41.4
Time in familiar zone, hab. session 22.52.63.61.3-1.61.6-1.6-1.6-1.71.6-1.61.81.8-1.61.6-1.6-1.71.91.61.61.5-1.8-1.41.61.61.6
Time in novel zone, hab. session 21.61.62.1-1.01.2-1.21.21.21.3-1.31.3-1.5-1.51.2-1.21.31.3-1.4-1.3-1.3-1.31.41.1-1.3-1.3-1.2
Total zone transitions, hab. session 22.43.14.6-2.21.5-1.51.51.51.7-1.91.9-1.8-1.81.9-1.81.81.8-1.8-1.9-2.0-1.51.52.0-1.8-1.8-1.7
Total locomotion distance, hab. session 20.00.00.1-0.4-0.20.2-0.2-0.20.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.2-0.2-0.0-0.40.2-0.4-0.2-0.1
Locomotion velocity, hab. session 20.10.10.3-0.50.1-0.10.10.10.2-0.20.2-0.2-0.20.3-0.30.20.3-0.2-0.3-0.3-0.2-0.20.3-0.4-0.3-0.2
Novel to familiar place preference ratio0.20.20.40.3-0.70.7-0.7-0.7-0.40.4-0.40.30.3-0.50.4-0.4-0.30.40.30.40.3-0.3-0.30.20.10.1
Novelty place preference0.10.10.30.2-0.50.5-0.5-0.5-0.20.3-0.30.20.2-0.40.3-0.2-0.20.30.20.30.2-0.1-0.20.1-0.0-0.1
Time in novel zone, NPP test0.00.00.1-0.0-0.30.3-0.3-0.3-0.00.1-0.1-0.0-0.0-0.10.1-0.00.00.0-0.00.0-0.00.1-0.0-0.1-0.2-0.3
Total zone transitions, NPP test0.10.10.3-0.40.5-0.50.50.50.3-0.30.3-0.2-0.20.4-0.30.30.3-0.2-0.2-0.3-0.40.10.2-0.3-0.1-0.3
Total locomotion distance, NPP test2.83.84.11.8-1.91.9-1.9-1.9-2.02.0-2.02.02.0-1.92.0-1.9-2.02.02.02.01.8-1.8-2.01.82.01.9
Locomotion velocity, NPP test3.04.34.81.9-2.02.0-2.0-2.0-2.12.1-2.12.12.1-2.12.1-2.0-2.22.22.12.11.9-2.0-2.11.92.12.0
Intraocular pressure0.00.00.2-0.3-0.00.0-0.0-0.0-0.20.0-0.0-0.4-0.30.00.10.0-0.1-0.40.1-0.00.0-0.50.2-0.20.2-0.0
Delta distance traveled before/after self-admin1.11.13.31.8-0.40.4-0.4-0.4-0.81.0-1.01.71.6-1.20.9-1.1-0.71.60.81.20.9-0.4-1.31.20.91.0
Delta ambulatory time before/after self-admin0.81.03.11.8-0.20.2-0.2-0.2-0.61.0-1.01.71.8-1.10.8-0.9-0.51.70.71.10.6-0.4-1.30.90.70.7
Parametrial fat weight0.20.51.7-0.20.8-0.80.80.80.8-0.80.8-0.3-0.20.7-0.80.70.90.1-0.8-0.6-0.91.30.7-0.1-0.7-0.7
Pavlov. Cond. lever latency0.00.00.10.3-0.20.2-0.2-0.2-0.10.2-0.20.20.2-0.20.2-0.2-0.10.20.10.20.10.2-0.40.30.10.1
Pavlov. Cond. magazine entry latency0.60.81.2-0.80.6-0.60.60.60.8-0.90.9-1.0-0.90.9-0.81.00.9-0.8-1.0-0.9-1.00.90.9-1.1-0.9-1.0
Pavlov. Cond. change in total contacts0.20.20.5-0.50.3-0.30.30.30.4-0.40.4-0.4-0.40.5-0.40.40.5-0.5-0.5-0.5-0.1-0.00.7-0.6-0.5-0.3
Pavlov. Cond. index score0.40.50.7-0.70.7-0.70.70.70.7-0.70.7-0.6-0.60.7-0.70.70.7-0.6-0.7-0.8-0.70.50.8-0.8-0.7-0.7
Pavlov. Cond. latency score0.10.20.3-0.60.4-0.40.40.40.4-0.40.4-0.4-0.40.5-0.50.40.4-0.4-0.4-0.5-0.40.20.6-0.5-0.4-0.3
Pavlov. Cond. lever contacts0.10.10.30.0-0.40.4-0.4-0.4-0.40.3-0.30.20.2-0.20.3-0.3-0.30.20.30.20.4-0.60.10.20.30.4
Pavlov. Cond. magazine entry number0.40.50.80.6-0.50.5-0.5-0.5-0.70.8-0.80.80.7-0.70.7-0.8-0.80.70.80.80.8-0.8-0.70.90.80.8
Pavlov. Cond. intertrial magazine entries0.60.81.4-1.10.9-0.90.90.90.8-0.90.9-1.0-1.00.9-0.90.80.9-1.0-0.8-0.9-0.40.71.2-0.5-0.8-0.4
Pavlov. Cond. lever-magazine prob. diff.0.60.81.1-0.80.8-0.80.80.80.9-0.90.9-0.9-0.80.9-0.90.90.9-0.8-1.0-1.0-0.90.71.0-1.1-0.9-0.9
Pavlov. Cond. response bias0.20.30.4-0.40.4-0.40.40.40.5-0.60.6-0.6-0.50.5-0.50.60.5-0.4-0.6-0.6-0.50.60.6-0.6-0.5-0.6
Pavlov. Cond. lever latency5.57.59.7-3.12.7-2.72.72.72.8-2.82.8-2.8-2.72.8-2.82.82.7-2.8-2.7-2.8-2.72.62.8-2.7-2.6-2.6
Pavlov. Cond. magazine entry latency4.25.06.02.3-2.12.1-2.1-2.1-2.32.3-2.32.22.2-2.22.2-2.3-2.32.32.22.22.4-2.4-2.22.32.22.2
Pavlov. Cond. change in total contacts7.912.714.03.7-3.73.7-3.7-3.7-3.63.7-3.63.33.3-3.63.6-3.6-3.63.23.63.63.7-3.1-3.63.63.43.4
Pavlov. Cond. index score6.48.611.13.3-2.92.9-2.9-2.9-3.03.0-3.02.92.8-3.03.0-3.0-2.92.92.92.93.0-2.8-3.03.02.92.8
Pavlov. Cond. latency score5.87.79.73.1-2.72.7-2.7-2.7-2.82.8-2.82.72.7-2.82.8-2.8-2.82.82.82.82.8-2.8-2.82.82.72.6
Pavlov. Cond. lever contacts6.08.310.73.3-2.92.9-2.9-2.9-2.92.9-2.92.82.8-2.92.9-2.9-2.92.82.92.92.9-2.7-2.92.92.72.7
Pavlov. Cond. magazine entry number4.35.47.3-2.72.2-2.22.22.22.4-2.32.3-2.2-2.22.3-2.32.42.3-2.3-2.4-2.3-2.42.02.5-2.5-2.3-2.2
Pavlov. Cond. intertrial magazine entries1.62.53.8-1.41.9-1.91.91.91.6-1.51.5-1.1-1.11.5-1.51.61.5-1.3-1.5-1.4-1.91.11.4-1.7-1.5-1.8
Pavlov. Cond. lever-magazine prob. diff.6.08.010.33.2-2.82.8-2.8-2.8-2.92.9-2.92.72.7-2.92.9-2.9-2.82.82.82.82.8-2.6-2.92.92.72.6
Pavlov. Cond. response bias6.99.412.13.5-3.03.0-3.0-3.0-3.13.1-3.13.02.9-3.13.1-3.1-3.03.03.13.13.1-2.8-3.23.12.92.9
Time in closed arm before self-admin1.11.54.1-1.40.5-0.50.50.51.0-1.11.1-1.7-2.01.2-1.01.20.9-2.0-1.1-1.2-1.21.21.2-1.4-1.1-1.0
Time in closed arm after self-admin0.80.82.10.2-1.31.3-1.3-1.3-1.10.8-0.80.0-0.1-0.60.9-0.7-1.20.01.00.60.8-1.5-0.50.60.91.0
Time in open arm before self-admin3.74.07.22.7-1.11.1-1.1-1.1-1.82.0-2.02.42.6-2.01.9-2.0-2.02.72.12.11.9-2.3-2.22.22.11.9
Time in open arm after self-admin0.40.41.91.00.0-0.00.00.0-0.20.5-0.51.31.4-0.70.4-0.6-0.11.20.20.60.50.1-0.70.60.40.3
Bone: periosteal estimation2.45.05.52.2-2.22.2-2.2-2.2-2.42.3-2.32.32.3-2.32.3-2.2-2.32.22.32.31.9-2.0-2.22.32.32.0
Bone: periosteal perimeter2.03.44.61.4-2.12.1-2.1-2.1-2.01.8-1.81.51.5-1.81.9-1.9-2.01.51.91.82.0-1.7-1.52.01.91.9
Bone: post-yield work2.23.24.31.7-1.71.7-1.7-1.7-1.91.9-1.91.91.9-1.81.9-1.9-1.91.71.91.91.7-2.1-1.91.61.81.5
Progressive ratio test 1 active lever presses0.00.00.1-0.10.0-0.00.00.0-0.10.1-0.1-0.00.00.00.1-0.0-0.1-0.20.10.00.1-0.2-0.2-0.30.20.3
Progressive ratio test 1 breakpoint0.00.00.2-0.0-0.10.1-0.1-0.1-0.30.2-0.20.10.1-0.10.2-0.2-0.3-0.10.20.10.2-0.4-0.3-0.20.30.5
Progressive ratio test 1 inactive lever presses0.30.42.00.1-0.70.7-0.7-0.7-0.80.7-0.70.40.6-0.50.7-0.6-0.70.30.70.50.5-1.4-0.40.10.50.7
Progressive ratio test 2 active lever presses0.30.31.3-0.80.4-0.40.40.40.4-0.40.4-1.0-0.90.5-0.40.50.2-1.2-0.3-0.5-0.40.70.3-0.6-0.2-0.2
Progressive ratio test 2 breakpoint0.40.51.7-0.90.5-0.50.50.50.5-0.60.6-1.1-1.10.7-0.50.70.4-1.3-0.4-0.6-0.50.80.4-0.8-0.4-0.3
Progressive ratio test 2 inactive lever presses0.81.33.60.3-1.31.3-1.3-1.3-1.31.2-1.20.30.4-0.91.2-1.1-1.40.21.20.91.4-1.9-0.70.61.21.4
Incentive Sensitization - Responses0.50.72.3-1.10.6-0.60.60.60.6-0.70.7-1.4-1.40.8-0.70.80.6-1.5-0.6-0.8-0.60.90.6-0.8-0.5-0.5
Incentive Sensitization - Breakpoint0.60.72.3-1.10.6-0.60.60.60.7-0.80.8-1.4-1.40.8-0.70.90.6-1.5-0.6-0.8-0.60.90.6-0.9-0.6-0.6
Sum of active levers in priming session hrs 5-60.10.10.3-0.40.5-0.50.50.50.2-0.20.2-0.4-0.20.3-0.20.10.1-0.3-0.2-0.20.0-0.10.1-0.20.10.0
Progressive ratio0.00.11.1-0.10.0-0.00.00.0-0.30.1-0.10.20.2-0.00.1-0.2-0.30.30.20.10.2-1.0-0.0-0.00.20.2
Food seeking constrained by brief footshock3.44.27.01.9-1.91.9-1.9-1.9-2.22.0-2.11.92.1-2.02.1-2.0-2.12.22.12.01.9-2.6-1.91.82.12.1
Seeking ratio, punishment vs. effort0.50.71.20.9-1.11.1-1.1-1.1-0.80.9-0.90.60.6-0.90.9-0.7-0.80.60.80.80.7-0.5-0.70.70.70.7
Retroperitoneal fat weight0.72.84.7-1.21.8-1.81.81.81.8-1.91.9-1.4-1.21.6-1.71.71.8-0.8-1.7-1.6-1.92.21.5-1.2-1.6-1.9
Reaction time number correct0.10.20.90.10.6-0.60.60.60.6-0.40.40.00.10.3-0.50.40.70.1-0.6-0.3-0.60.90.2-0.4-0.5-0.6
Reaction time mean minus median0.10.20.50.7-0.20.2-0.2-0.2-0.30.4-0.40.60.4-0.50.4-0.4-0.30.50.30.50.1-0.3-0.60.30.30.1
Reaction time mean minus median AUC0.10.31.51.2-0.20.2-0.2-0.2-0.40.6-0.61.00.8-0.80.5-0.5-0.30.90.40.7-0.0-0.1-0.90.40.40.1
Reaction time num false alarms1.42.02.8-1.21.4-1.41.41.41.5-1.31.3-1.5-1.61.3-1.41.41.5-1.6-1.4-1.3-1.41.71.1-1.3-1.5-1.7
Reaction time num false alarms AUC1.62.53.2-1.31.7-1.71.71.71.6-1.51.5-1.7-1.71.5-1.51.51.6-1.7-1.5-1.5-1.61.51.2-1.5-1.5-1.8
Reaction time trials correct on left0.10.20.90.10.6-0.60.60.60.6-0.40.40.00.10.3-0.50.40.70.1-0.6-0.3-0.60.90.2-0.4-0.5-0.6
Reaction time trials on left0.10.31.00.10.6-0.60.60.60.6-0.40.40.00.10.3-0.60.40.80.1-0.6-0.3-0.61.00.2-0.4-0.5-0.7
Reaction time mean0.10.10.30.50.6-0.60.60.60.2-0.00.00.10.1-0.1-0.10.10.3-0.0-0.10.1-0.20.2-0.40.0-0.1-0.1
Reaction time mean AUC0.10.20.70.50.8-0.80.80.80.3-0.20.20.00.00.1-0.20.20.4-0.0-0.2-0.1-0.30.2-0.3-0.0-0.2-0.2
Median of all reaction times0.20.30.90.20.9-0.90.90.90.5-0.40.4-0.3-0.20.3-0.40.40.6-0.4-0.4-0.3-0.40.40.0-0.3-0.4-0.4
Reaction time omissions0.30.41.1-0.30.7-0.70.70.70.7-0.50.5-0.2-0.20.4-0.60.60.7-0.2-0.7-0.4-1.01.00.2-0.5-0.6-1.0
Reaction time false alarm rate0.81.12.1-1.11.0-1.01.01.01.0-1.01.0-1.3-1.41.0-0.91.00.9-1.4-0.9-1.0-0.90.70.8-1.0-1.0-1.1
Reaction time premature initiation rate0.10.10.80.1-0.40.4-0.4-0.4-0.30.3-0.30.60.4-0.30.2-0.3-0.20.50.10.20.2-0.9-0.1-0.00.20.3
Reaction time premature initiations0.00.10.30.0-0.00.0-0.0-0.00.10.1-0.10.50.4-0.0-0.1-0.00.20.4-0.3-0.0-0.2-0.30.0-0.3-0.2-0.2
Std. dev. reaction times0.10.20.91.00.0-0.00.00.0-0.20.4-0.40.60.5-0.60.4-0.3-0.20.40.30.50.0-0.0-0.80.30.30.1
Reaction time trials completed0.10.31.00.10.6-0.60.60.60.6-0.40.40.00.10.3-0.60.40.80.1-0.6-0.3-0.61.00.2-0.4-0.5-0.7
Reaction time trials AUC0.20.41.4-0.10.8-0.80.80.80.8-0.60.6-0.10.00.5-0.70.50.9-0.0-0.7-0.5-0.81.20.3-0.5-0.6-0.8
Run reversals in cocaine runway, females0.10.10.70.80.0-0.00.00.0-0.10.4-0.40.60.7-0.50.3-0.3-0.10.50.30.50.10.1-0.70.20.10.1
Run reversals in cocaine runway, males0.50.51.60.21.2-1.21.21.20.8-0.70.7-0.00.10.6-0.70.50.70.4-0.6-0.5-0.40.80.30.0-0.3-0.3
Latency to leave start box in cocaine runway0.00.10.30.20.1-0.10.10.10.10.2-0.20.40.6-0.2-0.0-0.10.20.20.00.1-0.20.4-0.4-0.1-0.00.1
Latency to leave start box in cocaine runway, F0.20.20.60.10.6-0.60.60.60.6-0.30.30.10.20.3-0.50.50.7-0.0-0.5-0.3-0.80.70.1-0.6-0.6-0.5
Latency to leave start box in cocaine runway, M0.10.10.2-0.2-0.50.5-0.5-0.5-0.30.2-0.20.10.1-0.20.2-0.3-0.2-0.20.30.20.10.2-0.30.10.20.3
Std. dev. time between licks in bursts0.70.92.4-0.1-1.31.3-1.3-1.3-1.00.9-0.90.90.9-0.80.8-0.9-0.90.90.80.71.1-1.6-0.30.80.61.0
Total sessions with >9 infusions1.82.23.2-1.31.8-1.81.81.81.5-1.51.5-1.3-1.31.5-1.51.41.4-1.4-1.5-1.4-1.41.61.2-1.4-1.3-1.3
Short access day 1 total inactive lever presses0.71.01.90.2-1.21.2-1.2-1.2-1.11.1-1.10.80.7-0.91.0-1.0-1.00.31.00.91.0-1.4-0.80.50.71.0
Short access day 10 total inactive lever presses2.45.89.91.4-2.72.7-2.7-2.7-2.62.5-2.51.81.9-2.32.5-2.4-2.61.62.52.32.7-3.1-1.92.12.42.6
Short access day 1 total infusions0.00.00.2-0.4-0.30.3-0.3-0.30.0-0.00.0-0.1-0.00.0-0.10.0-0.0-0.2-0.1-0.10.00.40.2-0.2-0.1-0.0
Short access day 10 total infusions0.50.71.3-0.81.0-1.01.01.00.7-0.80.8-1.0-1.00.8-0.70.70.6-1.1-0.7-0.8-0.60.70.5-0.8-0.5-0.5
Short access total infusions0.91.21.7-1.21.1-1.11.11.11.1-1.11.1-1.2-1.21.1-1.11.01.0-1.3-1.0-1.1-1.01.30.9-1.1-1.0-1.0
Short access day 1 locomotion1.92.44.0-1.02.0-2.02.02.01.7-1.51.5-0.9-1.01.5-1.61.41.7-1.1-1.5-1.4-1.61.51.2-1.4-1.6-1.6
Short access day 10 total locomotion0.51.04.80.5-0.50.5-0.5-0.5-1.00.9-0.90.90.9-0.70.9-1.1-1.10.81.00.81.2-2.2-0.70.81.21.4
Short access total locomotion1.11.31.7-1.21.3-1.31.31.31.1-1.21.2-1.0-1.01.3-1.21.11.0-1.1-1.1-1.2-1.10.51.1-1.3-1.0-1.0
One hour access (0.3 mA shock)0.60.71.30.6-1.11.1-1.1-1.1-0.81.0-1.00.40.4-0.80.9-0.7-0.90.20.80.80.7-0.9-0.90.20.70.8
Compulsive drug intake0.30.41.6-0.1-1.21.2-1.2-1.2-0.40.5-0.50.30.3-0.50.5-0.2-0.20.30.20.30.0-0.40.1-0.2-0.2-0.1
One hour access (shock baseline)0.00.10.3-0.0-0.10.1-0.1-0.1-0.20.1-0.1-0.4-0.4-0.00.1-0.1-0.4-0.50.20.10.2-0.0-0.3-0.10.30.4
Social response proportion3.23.75.81.4-2.32.3-2.3-2.3-2.11.9-1.91.51.5-1.81.9-1.9-2.11.51.91.81.9-2.4-1.51.52.01.9
Social responses0.91.14.10.6-0.90.9-0.9-0.9-1.11.1-1.11.21.1-1.01.0-1.1-1.11.11.11.11.0-2.0-0.60.81.11.0
Social time2.53.45.01.7-1.51.5-1.5-1.5-2.01.9-1.91.91.9-1.91.9-1.9-1.81.61.91.92.0-2.2-1.91.71.92.2
Soleus weight0.10.20.5-0.20.7-0.70.70.70.4-0.50.5-0.0-0.10.4-0.50.40.5-0.1-0.5-0.4-0.70.40.3-0.5-0.3-0.6
Bone: stiffness1.62.53.01.7-1.41.4-1.4-1.4-1.71.6-1.61.61.6-1.61.7-1.7-1.71.51.71.61.7-1.5-1.71.61.61.4
Tibialis anterior weight0.10.31.8-0.40.5-0.50.50.50.5-0.60.6-0.3-0.30.5-0.50.50.5-0.3-0.5-0.5-0.51.30.4-0.1-0.4-0.4
Time to tail flick, vehicle, before self-admin0.70.71.3-0.51.1-1.11.11.10.8-0.80.8-1.1-1.00.8-0.80.80.8-1.0-0.7-0.7-0.90.80.6-0.6-0.7-0.8
Time to tail flick, vehicle, after self-admin1.31.73.90.4-1.51.5-1.5-1.5-1.51.2-1.20.50.5-1.11.4-1.2-1.60.71.41.11.4-2.0-0.71.11.51.5
Time to tail flick, test, before self-admin0.50.51.4-0.10.7-0.70.70.70.7-0.40.5-0.8-0.80.5-0.60.60.7-1.1-0.5-0.5-0.81.2-0.0-0.6-0.7-0.7
Time to tail flick, test, after self-admin0.00.00.1-0.20.0-0.00.00.00.2-0.20.2-0.2-0.30.3-0.20.30.1-0.2-0.1-0.2-0.40.10.3-0.1-0.2-0.4
Delta time to tail flick, vehicle, before/after SA1.31.32.20.9-1.21.2-1.2-1.2-1.11.1-1.11.21.1-1.11.1-1.1-1.21.31.11.11.1-1.5-0.90.91.11.1
Delta time to tail flick, test, before/after SA0.10.10.6-0.5-0.20.2-0.2-0.20.1-0.20.20.00.10.3-0.10.20.00.4-0.2-0.2-0.2-0.30.8-0.2-0.0-0.2
Tibia length2.26.19.23.0-2.12.1-2.1-2.1-2.42.4-2.42.62.5-2.52.4-2.5-2.42.62.62.52.4-1.9-3.02.72.52.4
Ambulatory time before self-admin0.81.32.70.0-1.61.6-1.6-1.6-1.41.0-1.00.70.7-0.91.2-1.0-1.40.61.20.91.0-1.6-0.60.71.00.9
Ambulatory time after self-admin4.14.96.52.2-1.81.8-1.8-1.8-2.32.3-2.32.52.5-2.32.3-2.2-2.22.62.32.31.9-2.5-2.32.02.11.9
Bone: tissue strength3.33.33.82.0-1.91.9-1.9-1.9-1.81.9-1.91.91.9-1.91.9-1.9-1.81.81.71.81.7-1.8-1.81.51.71.7
Total heroin consumption0.40.51.60.4-0.60.6-0.6-0.6-0.80.8-0.80.60.6-0.70.8-0.8-0.80.40.80.70.6-1.3-0.80.20.70.6
Bone: trabecular number0.91.53.21.8-0.60.6-0.6-0.6-1.21.2-1.21.51.5-1.21.1-1.3-1.21.51.31.31.1-1.0-1.71.51.31.0
Bone: trabecular spacing0.60.71.50.4-1.21.2-1.2-1.2-0.80.8-0.80.70.8-0.90.9-0.8-0.80.80.70.81.0-0.6-0.50.70.70.7
Bone: trabecular thickness0.20.31.3-0.10.6-0.60.60.60.6-0.50.5-0.4-0.40.5-0.60.50.6-0.5-0.4-0.5-0.61.10.1-0.2-0.5-0.6
Bone: trabecular tissue density1.92.84.7-1.41.7-1.71.71.71.7-1.81.8-1.9-1.81.7-1.71.71.6-1.6-1.6-1.7-1.72.21.5-1.3-1.5-1.6
Water consumed over 24 hours0.30.41.41.2-0.40.4-0.4-0.4-0.60.6-0.60.70.7-0.60.6-0.6-0.60.70.70.60.5-0.6-0.80.80.70.6
Number of responses in last shaping day0.30.30.9-0.0-1.01.0-1.0-1.0-0.60.5-0.50.40.3-0.40.5-0.5-0.60.10.50.40.60.2-0.40.50.50.5