Hub : Genes

Zfp354a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Zfp354a 0.05 0.03 2.0e-04 0.05 0.04 0.04 0.04 2.3e-06 5.8e-05 1.7e-05 1.3e-05
2 NAcc gene expression Zfp354a 0.09 0.04 2.0e-11 0.06 0.07 0.06 0.06 1.5e-09 2.5e-11 1.0e-09 7.3e-10
3 PL gene expression Zfp354a 0.06 0.04 2.3e-04 0.03 0.04 0.04 0.04 2.3e-04 1.5e-05 3.1e-05 3.6e-05
4 Liver mRNA stability Zfp354a 0.07 0.04 1.2e-04 0.01 0.03 0.03 0.03 1.8e-02 2.7e-04 1.1e-04 4.4e-04
5 Brain gene expression Zfp354a 0.09 0.04 4.3e-06 0.05 0.06 0.05 0.06 2.1e-05 1.6e-06 1.3e-05 4.5e-06
6 Brain mRNA stability Zfp354a 0.04 0.03 6.2e-03 0.01 0.01 0 0.01 3.5e-02 4.4e-02 1.9e-01 7.1e-02
7 pVTA gene expression Zfp354a 0.05 0.03 1.8e-03 0.05 0.03 0.04 0.04 9.6e-05 1.1e-03 4.6e-04 4.3e-04
8 pVTA mRNA stability Zfp354a 0.07 0.04 1.9e-04 0.05 0.04 0.04 0.05 5.1e-05 2.7e-04 2.7e-04 7.5e-05
9 Adipose mRNA stability Zfp354a 0.04 0.04 5.5e-03 0.02 0.01 0.01 0.02 3.6e-03 4.5e-02 8.6e-03 5.8e-03
10 NAcc mRNA stability Zfp354a 0.04 0.03 1.6e-04 0.02 0.03 0.03 0.03 3.8e-04 2.3e-05 2.2e-05 2.3e-05
11 IC gene expression Zfp354a 0.12 0.08 2.5e-03 0.06 0.05 0.02 0.04 1.6e-03 4.4e-03 3.3e-02 5.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.50.93.3-0.51.41.81.11.00.8-0.8-0.80.5-0.4-0.2
Area under the delay curve0.50.82.50.41.41.61.00.80.8-0.8-0.80.1-0.30.3
BMI with tail0.93.16.12.22.12.51.32.21.8-1.7-1.7-0.51.6-0.3
BMI without tail0.73.87.32.22.42.72.12.22.0-2.1-2.1-0.71.10.2
Body weight1.25.410.62.42.93.22.42.72.6-2.5-2.5-1.01.30.3
Weight adjusted by age0.61.94.41.70.90.51.31.11.7-1.3-1.3-2.11.11.2
Bone surface0.20.41.4-0.81.01.20.50.70.5-0.4-0.40.4-0.4-0.2
Bone volume0.30.72.6-0.61.31.60.40.90.5-0.5-0.50.8-0.2-0.5
Breakpoint value in progressive ratio session0.71.33.80.70.7-0.01.40.11.1-1.4-1.4-1.6-0.41.9
Number of licking bursts0.20.62.10.70.0-0.31.30.00.7-0.7-0.7-1.4-0.21.1
Context. condit. distance diff. score0.70.81.61.20.80.61.30.71.1-1.0-1.0-1.10.40.7
Locomotion velocity, session 10.10.10.30.5-0.20.00.5-0.1-0.1-0.1-0.1-0.2-0.1-0.3
Locomotion distance, session 10.50.61.71.3-0.4-0.30.40.50.6-0.4-0.4-1.31.3-0.3
Locomotion velocity, session 20.50.52.11.1-0.10.10.20.80.5-0.6-0.6-0.91.4-0.5
Locomotion distance, session 21.31.94.32.10.50.71.01.51.4-1.3-1.3-1.72.0-0.3
Locomotion velocity, session 33.74.37.82.81.40.92.31.62.4-2.2-2.2-2.81.41.7
Locomotion distance, session 32.42.74.72.21.41.21.91.52.0-1.8-1.8-1.91.00.9
Stereotopy head waving bouts, day 30.40.51.2-1.1-0.9-0.8-0.7-0.7-0.70.80.80.3-0.4-0.3
Stereotopy head waving duration, day 30.50.61.7-1.1-0.9-1.3-1.0-0.8-0.60.60.6-0.2-0.10.3
Locomotion velocity, session 70.30.31.5-0.6-0.00.0-1.20.4-0.10.20.20.51.0-0.7
Locomotion distance, session 70.10.10.6-0.8-0.2-0.4-0.7-0.0-0.10.20.20.10.20.0
Stereotopy head waving bouts, day 70.60.72.1-0.1-0.7-0.3-1.40.4-0.40.30.30.11.4-1.4
Stereotopy head waving duration, day 70.20.31.10.0-0.5-0.4-1.00.1-0.30.30.30.11.0-0.7
Locomotion velocity, session 84.25.19.32.41.71.42.62.22.8-2.6-2.6-3.11.71.0
Locomotion distance, session 82.94.28.22.91.61.52.32.02.4-2.2-2.2-2.31.80.8
Degree of sensitization distance2.42.66.2-2.1-1.5-1.5-2.5-1.2-1.81.71.71.5-0.2-1.0
Degree of sensitization stereotypy0.60.73.0-0.0-0.50.1-1.40.5-0.50.40.40.61.3-1.7
Conditioned locomotion0.20.20.6-0.50.20.6-0.60.3-0.20.00.00.80.1-0.8
Cocaine response after cond. corrected0.40.71.7-1.1-0.20.3-1.20.1-0.60.60.61.20.2-1.3
Cocaine response after cond. not corrected0.71.02.3-1.2-0.5-0.0-1.5-0.2-0.90.90.91.50.1-1.4
Cocaine response before conditioning0.10.10.30.50.40.4-0.00.40.2-0.2-0.20.20.5-0.1
Saline control response0.10.10.5-0.70.00.0-0.60.1-0.20.10.10.30.1-0.3
Bone: connectivity density0.20.21.3-1.10.30.40.60.20.3-0.2-0.2-0.2-0.70.2
Bone: cortical apparent density0.20.30.8-0.6-0.7-0.9-0.0-0.8-0.40.40.4-0.2-0.80.4
Bone: cortical area1.21.96.70.42.22.60.71.81.2-1.2-1.20.70.6-0.6
Bone: cortical porosity2.42.66.51.51.92.5-0.12.31.2-1.1-1.10.72.1-1.5
Bone: cortical porosity1.82.05.80.91.72.4-0.52.00.8-0.7-0.71.21.7-1.6
Bone: cortical thickness2.54.29.11.52.93.02.32.32.2-2.2-2.2-0.60.60.5
Bone: cortical thickness2.73.38.51.32.92.71.62.01.9-1.9-1.9-0.20.60.9
Bone: cortical tissue density0.30.41.1-0.6-0.8-1.0-0.1-0.9-0.50.50.5-0.3-0.80.4
Condit. Reinf. active minus inactive responses1.01.23.6-0.1-1.4-0.6-1.2-0.6-1.21.11.10.90.2-1.9
Condit. Reinf. active-inactive response ratio0.50.51.40.4-1.2-1.0-0.9-0.5-0.70.50.5-0.10.6-0.7
Condit. Reinf. active responses1.52.03.1-0.8-1.6-0.8-1.4-1.2-1.71.71.71.6-0.7-1.8
Condit. Reinf. inactive responses0.81.13.2-1.1-0.10.2-0.4-0.9-0.91.11.11.8-1.7-0.5
Incentive salience index mean0.30.41.70.4-0.8-0.2-0.5-0.2-0.60.50.50.40.2-1.3
Condit. Reinf. lever presses0.10.10.50.70.10.40.20.20.1-0.1-0.10.00.2-0.4
Condit. Reinf. active minus inactive responses2.43.76.3-2.1-1.5-0.8-2.5-1.3-2.12.22.22.5-0.9-2.0
Condit. Reinf. active-inactive response ratio1.52.44.8-2.2-1.1-0.8-1.5-1.4-1.61.71.71.9-1.5-0.9
Condit. Reinf. active responses2.63.86.7-2.5-1.6-1.2-2.6-1.5-2.12.22.22.2-1.1-1.5
Condit. Reinf. inactive responses0.30.50.9-0.9-0.5-0.6-0.9-0.6-0.70.80.80.6-0.6-0.1
Condit. Reinf. lever presses2.13.04.0-2.0-1.7-1.7-1.8-2.0-1.92.02.01.4-1.7-0.4
Condit. Reinf. lever reinforcers received3.14.37.2-2.6-1.8-1.4-2.7-1.7-2.32.42.42.3-1.2-1.6
Conditioned reinforcement - actives0.10.41.11.0-0.7-0.9-0.0-0.10.0-0.0-0.0-0.91.00.2
Conditioned reinforcement - inactives0.00.10.30.20.40.50.3-0.00.1-0.1-0.10.3-0.4-0.1
Conditioned locomotion0.30.40.60.0-0.7-0.5-0.7-0.5-0.70.80.80.70.3-0.7
Patch foraging indifference point 0 sec0.41.14.7-1.0-0.4-0.80.3-1.5-0.80.70.70.6-2.21.0
Patch foraging indifference point AUC1.02.45.7-2.4-1.1-0.3-2.1-0.4-1.41.31.32.0-0.2-2.4
Delay disc. indifference point, 0s delay1.31.53.11.11.51.21.81.11.3-1.2-1.2-1.10.21.3
Delay disc. indifference point, 16s delay0.91.32.91.01.71.71.60.91.2-1.0-1.0-0.3-0.30.7
Delay disc. indifference point, 2s delay0.70.82.30.81.21.51.10.90.9-0.9-0.9-0.1-0.10.1
Delay disc. indifference point, 24s delay0.71.12.40.91.61.41.21.01.2-1.1-1.1-0.50.10.7
Delay disc. indifference point, 4s delay0.80.92.9-1.20.10.4-0.5-0.5-0.90.90.91.7-1.2-0.7
Delay disc. indifference point, 8s delay0.20.30.80.10.70.80.90.10.4-0.5-0.5-0.0-0.70.4
Indifference point function ln k0.31.03.11.81.31.11.10.70.8-0.8-0.8-0.30.31.0
Indifference point function log k0.31.03.11.81.31.11.10.70.8-0.8-0.8-0.30.31.0
Patch foraging total patch changes 0 sec0.51.55.7-1.5-0.5-0.80.0-1.6-1.11.01.01.1-2.40.7
Patch foraging total patch changes 12 sec3.44.69.9-3.1-2.3-2.3-1.4-2.5-2.32.02.01.4-2.4-0.5
Patch foraging total patch changes 18 sec0.20.42.4-1.50.10.20.3-0.2-0.20.00.00.5-1.4-0.2
Patch foraging total patch changes 24 sec0.72.36.1-2.5-1.3-1.1-1.0-1.5-1.51.61.61.5-1.8-0.9
Patch foraging total patch changes 6 sec1.52.55.8-2.4-1.6-1.6-0.9-1.8-1.71.61.61.2-1.7-0.5
Patch foraging time to switch 0 sec0.10.42.00.5-0.4-0.80.6-0.10.4-0.4-0.4-1.40.30.8
Patch foraging water rate 0 sec0.20.71.5-0.8-0.6-0.3-0.2-1.0-1.00.90.91.2-1.2-0.5
Patch foraging water rate 12 sec0.20.61.60.51.21.31.10.70.8-0.7-0.7-0.1-0.20.4
Patch foraging water rate 18 sec0.30.63.1-0.50.30.10.6-0.9-0.50.50.50.9-1.80.6
Patch foraging water rate 24 sec0.40.61.5-0.6-0.5-0.8-0.2-1.2-0.80.70.70.5-1.20.6
Patch foraging water rate 6 sec0.30.41.51.00.70.81.20.40.6-0.5-0.5-0.2-0.10.4
Seeking ratio, delayed vs. immediate footshock1.01.43.61.91.21.01.21.21.3-1.2-1.2-0.91.00.6
Distance traveled before self-admin0.10.20.8-0.40.30.2-0.6-0.0-0.40.20.20.9-0.0-0.1
Distance traveled after self-admin0.20.31.00.20.30.4-0.80.4-0.30.30.31.00.8-0.8
Extensor digitorum longus weight0.10.42.00.6-0.6-0.4-0.70.3-0.20.10.10.01.4-0.9
Bone: elastic displacement0.40.51.71.30.80.90.80.70.5-0.6-0.6-0.20.6-0.0
Bone: elastic work4.05.39.62.53.12.62.81.92.4-2.5-2.5-1.30.52.0
Bone: endosteal estimation1.12.66.9-2.0-1.0-0.5-2.6-0.7-1.71.61.62.3-0.1-1.7
Bone: endosteal perimeter1.84.38.5-2.5-1.6-0.8-2.9-1.1-2.22.22.22.7-0.4-2.5
Epididymis fat weight0.21.22.61.31.51.61.11.11.2-1.1-1.1-0.20.30.3
Delta time in closed arm before/after self-admin2.32.23.2-1.4-1.8-1.2-1.2-1.3-1.81.81.81.2-0.7-1.7
Delta time in open arm before/after self-admin0.70.81.51.11.01.00.21.10.8-0.9-0.9-0.31.20.3
Diff in mean of infusions in LGA sessions1.32.47.80.70.1-0.82.3-1.50.6-0.6-0.6-1.5-2.52.8
Delay discount exponential model param0.50.72.5-0.3-1.4-1.6-0.8-0.8-0.80.70.7-0.30.2-0.1
Extinction: sum of active levers before priming3.65.47.92.42.72.22.81.92.6-2.8-2.8-2.00.61.8
Active lever presses in extinction session 60.10.10.3-0.0-0.4-0.50.1-0.5-0.3-0.2-0.2-0.2-0.30.1
Bone: final force0.81.33.40.31.41.9-0.41.70.8-0.8-0.80.71.5-1.2
Bone: final moment1.01.63.80.61.51.90.11.91.1-1.1-1.10.31.6-1.0
Food consumed during 24 hour testing period0.61.25.11.00.70.82.30.71.1-1.1-1.1-1.3-0.30.6
Glucose0.20.31.00.20.70.40.8-0.10.4-0.3-0.30.0-1.01.0
Heart weight5.18.110.83.33.13.12.83.33.2-3.2-3.2-2.12.40.8
Delay discount hyperbolic model param0.50.72.3-0.3-1.4-1.5-0.8-0.8-0.80.70.7-0.20.3-0.2
Intermittent access intake day 1-15 change0.00.20.91.00.30.4-0.40.20.0-0.1-0.10.40.9-0.4
Intermittent access intake escalation0.00.21.01.00.40.4-0.10.00.0-0.1-0.10.50.4-0.0
Intermittent access intake escalation 20.10.20.70.30.60.8-0.10.4-0.00.00.00.80.3-0.5
Intermitt. access day 1 inactive lever presses0.11.43.81.91.10.71.00.81.4-1.2-1.2-1.10.81.1
Intermitt. access day 15 inactive lever presses0.10.61.20.81.10.70.70.60.9-0.8-0.8-0.60.30.9
Intermitt. access escalation Index0.10.20.7-0.3-0.4-0.0-0.60.2-0.60.10.10.20.5-0.9
Intermittent access day 1 total infusions0.20.61.91.00.50.40.11.00.8-0.7-0.7-0.81.40.0
Intermittent access day 15 total infusions0.40.94.02.00.80.90.20.90.7-0.7-0.7-0.41.50.0
Intermittent access terminal intake (last 3 days)0.81.53.71.91.31.70.21.50.8-0.7-0.70.11.8-0.6
Intermittent access total infusions0.91.13.11.80.91.10.51.30.8-0.8-0.8-0.51.6-0.3
Intermittent access day 1 locomotion0.10.21.20.4-0.2-0.1-0.30.40.3-0.2-0.2-0.61.1-0.2
Intermittent access day 15 total locomotion0.20.82.8-0.4-0.8-0.6-1.7-0.0-0.70.80.80.81.3-1.1
Intermittent access total locomotion0.60.71.80.3-0.9-0.7-1.3-0.0-0.60.70.70.41.3-1.1
Intermittent access standard deviation1.15.612.12.83.33.52.32.72.2-2.2-2.2-0.61.70.4
Left kidney weight1.08.212.93.62.82.72.53.03.3-3.4-3.4-2.42.51.1
Right kidney weight0.96.410.93.32.12.22.52.72.8-2.9-2.9-2.42.50.5
Cocaine induced anxiety0.20.61.6-0.11.31.10.21.10.7-0.8-0.80.00.60.1
Post-drug Anxiety0.50.52.3-1.5-0.1-0.4-0.9-0.5-0.60.60.60.8-0.70.1
Baseline Anxiety2.54.27.2-1.7-2.7-2.7-1.6-2.6-2.22.32.30.9-1.8-0.4
Tail length0.31.43.40.61.41.51.91.21.2-1.4-1.4-0.70.00.3
Length with tail0.41.83.80.81.71.51.91.11.5-1.6-1.6-0.9-0.01.0
Length without tail0.10.40.80.30.90.80.80.60.9-0.6-0.6-0.3-0.10.7
Times rat made contact with spout0.50.62.10.9-0.2-0.41.4-0.20.5-0.5-0.5-1.4-0.20.8
Lifetime Intake1.72.15.42.31.31.51.01.71.4-1.3-1.3-0.91.8-0.1
Liver weight, left3.66.311.42.93.22.83.42.02.7-2.6-2.6-1.50.42.0
Liver weight, right7.312.728.64.14.85.32.64.43.6-3.6-3.6-0.52.7-0.2
Locomotor activity0.40.61.80.31.01.3-0.50.80.0-0.1-0.11.30.6-0.8
Locomotor testing distance0.10.41.4-0.2-0.10.0-0.8-0.5-0.70.60.61.2-0.3-0.4
Locomotor testing rearing0.20.61.9-1.1-0.10.2-0.8-0.5-0.80.70.71.4-0.8-0.5
Locomotion in novel chamber1.11.53.70.1-1.9-1.8-0.7-1.7-1.41.31.30.5-0.8-0.4
Locomotion in novel chamber post-restriction1.03.15.0-2.2-2.1-1.4-2.0-1.4-2.01.81.81.5-1.0-1.7
Fecal boli incidents, locomotor time 10.20.61.80.40.91.30.01.20.3-0.5-0.50.60.8-1.2
Change in fecal boli incidents, locomotor task0.20.20.60.00.60.70.70.10.2-0.4-0.40.2-0.40.3
Time >=10cm from walls, locomotor time 10.81.02.5-1.5-0.10.2-1.3-0.5-0.71.01.01.6-0.8-0.7
Bouts of movement, locomotor time 10.20.20.8-0.00.80.90.30.2-0.00.10.10.8-0.50.0
Total resting periods, locomotor time 10.40.41.60.21.31.20.70.50.4-0.3-0.30.4-0.50.5
Rest time, locomotor task time 10.61.02.60.41.61.20.51.41.1-1.1-1.1-0.40.90.7
Distance moved, locomotor task time 10.20.51.6-0.6-0.7-0.90.0-1.1-0.50.40.4-0.0-1.30.6
Vertical activity count, locomotor time 10.10.41.0-0.0-1.0-1.0-0.5-1.0-0.70.50.50.2-0.3-0.0
Time >=10cm from walls, locomotor time 20.20.42.2-0.40.20.6-0.4-0.3-0.60.50.51.5-0.7-0.7
Bouts of movement, locomotor time 20.20.62.7-1.00.1-0.40.4-0.9-0.30.30.30.2-1.61.1
Total resting periods, locomotor time 20.10.62.5-0.90.1-0.40.4-0.9-0.30.20.20.2-1.61.2
Rest time, locomotor task time 20.30.51.50.21.21.20.11.00.4-0.4-0.40.30.6-0.1
Distance moved, locomotor task time 20.70.93.0-0.3-1.5-1.70.0-1.4-0.60.50.5-0.7-1.00.6
Vertical activity count, locomotor time 20.20.52.00.1-1.3-1.4-0.3-0.7-0.30.00.0-0.90.20.2
Light reinforcement 10.00.20.60.1-0.5-0.30.7-0.6-0.40.40.4-0.1-0.80.0
Light reinforcement 20.10.21.00.50.20.10.7-0.6-0.00.20.20.2-1.00.6
Bone: marrow area1.02.56.9-1.9-1.0-0.6-2.6-0.7-1.61.61.62.2-0.0-1.7
Bone: maximum diameter0.40.82.7-0.70.41.0-1.10.5-0.40.40.41.70.4-1.5
Bone: maximum force0.71.43.60.41.81.90.11.81.2-1.1-1.10.31.2-0.4
Bone: maximum moment1.01.83.90.81.92.00.51.91.5-1.4-1.4-0.21.3-0.1
Mean time between licks in bursts0.10.83.00.0-1.5-1.7-0.3-1.1-0.70.70.7-0.8-0.20.4
Mean num. licks in bursts0.10.10.3-0.3-0.2-0.0-0.3-0.3-0.40.40.40.6-0.3-0.3
Cd content in liver3.33.75.6-2.1-2.3-2.1-1.0-2.4-2.22.22.21.2-2.1-0.5
Co content in liver0.10.10.30.50.20.30.10.30.1-0.1-0.10.10.5-0.3
Cu content in liver2.12.54.8-0.9-1.4-1.2-1.5-1.8-2.01.91.92.2-1.3-0.7
Fe content in liver1.11.32.01.31.11.01.41.11.4-1.2-1.2-1.20.50.7
K content in liver0.40.41.70.8-0.30.3-0.20.60.1-0.1-0.1-0.11.1-1.3
Mg content in liver0.91.02.3-0.8-1.5-1.0-1.1-0.7-1.21.01.00.60.0-1.5
Mn content in liver1.21.43.6-1.0-0.8-0.1-1.3-0.7-1.31.31.31.9-0.7-1.6
Na content in liver0.40.51.00.80.60.40.90.50.9-0.7-0.7-1.00.20.7
Rb content in liver0.40.41.1-0.5-1.0-0.9-0.9-0.4-0.70.40.40.10.4-0.8
Se content in liver0.50.72.31.00.20.11.50.30.7-0.8-0.8-1.30.00.6
Sr content in liver0.50.41.6-0.3-0.4-0.60.7-0.9-0.30.30.3-0.3-1.30.8
Zn content in liver0.30.30.8-0.6-0.9-0.6-0.4-0.5-0.70.60.60.4-0.2-0.7
Bone: minimum diameter0.20.41.3-1.10.60.9-0.40.60.1-0.1-0.10.9-0.0-0.7
Time in familiar zone, hab. session 10.30.31.4-0.50.91.2-0.10.40.1-0.0-0.01.0-0.3-0.4
Time in novel zone, hab. session 10.60.62.40.70.50.6-0.21.20.8-0.7-0.7-0.61.6-0.4
Total zone transitions, hab. session 10.81.14.31.3-1.3-0.8-0.40.50.1-0.1-0.1-1.32.1-1.3
Total locomotion distance, hab. session 10.50.72.50.90.30.7-0.11.20.7-0.6-0.6-0.51.6-0.8
Locomotion velocity, hab. session 10.60.92.01.40.40.40.61.01.0-0.9-0.9-1.21.4-0.1
Time in familiar zone, hab. session 22.73.08.71.32.63.00.92.31.6-1.7-1.70.31.2-0.5
Time in novel zone, hab. session 20.60.72.0-0.8-1.2-1.4-0.4-1.0-0.70.80.8-0.3-0.60.3
Total zone transitions, hab. session 21.62.07.31.8-0.10.30.41.61.2-1.2-1.2-1.92.7-1.0
Total locomotion distance, hab. session 21.21.54.11.60.20.50.61.41.2-1.2-1.2-1.62.0-0.7
Locomotion velocity, hab. session 21.41.84.01.80.30.40.91.41.4-1.4-1.4-1.92.0-0.3
Novel to familiar place preference ratio0.81.12.2-1.1-1.3-1.0-1.5-0.7-1.11.11.10.80.1-1.0
Novelty place preference0.50.61.5-0.9-0.9-0.7-1.2-0.4-0.90.80.80.70.2-0.8
Time in novel zone, NPP test0.40.51.4-0.9-0.7-0.6-1.2-0.2-0.70.70.70.60.3-0.8
Total zone transitions, NPP test0.40.61.50.4-1.2-0.9-0.60.1-0.20.20.2-0.81.2-1.0
Total locomotion distance, NPP test0.30.42.10.80.10.2-0.30.80.5-0.4-0.4-0.51.5-0.5
Locomotion velocity, NPP test0.20.31.40.6-0.5-0.3-0.90.2-0.20.20.20.01.2-0.9
Intraocular pressure0.10.10.40.1-0.4-0.60.3-0.3-0.10.20.2-0.50.00.4
Delta distance traveled before/after self-admin0.10.20.4-0.2-0.5-0.2-0.1-0.3-0.40.60.60.4-0.2-0.6
Delta ambulatory time before/after self-admin0.61.01.7-0.7-1.3-0.9-1.2-0.8-1.01.31.30.9-0.1-1.1
Parametrial fat weight0.10.32.4-0.0-0.30.6-0.00.4-0.20.10.10.40.3-1.6
Pavlov. Cond. lever latency0.20.31.0-1.0-0.6-0.5-0.7-0.2-0.30.40.40.20.0-0.5
Pavlov. Cond. magazine entry latency0.81.02.8-0.8-0.30.4-0.9-0.3-1.01.11.11.7-0.4-1.6
Pavlov. Cond. change in total contacts1.21.22.0-0.9-1.1-0.7-1.1-1.0-1.31.41.41.3-0.8-1.0
Pavlov. Cond. index score0.30.41.1-0.3-0.40.0-0.5-0.4-0.80.80.81.1-0.4-0.8
Pavlov. Cond. latency score0.10.10.50.20.10.4-0.0-0.1-0.30.30.30.7-0.4-0.4
Pavlov. Cond. lever contacts0.00.10.40.60.00.00.2-0.2-0.20.00.00.2-0.20.1
Pavlov. Cond. magazine entry number1.51.92.91.41.20.61.60.91.6-1.7-1.7-1.70.61.7
Pavlov. Cond. intertrial magazine entries4.35.111.5-2.0-3.4-2.9-2.0-2.2-2.42.62.60.8-0.8-1.7
Pavlov. Cond. lever-magazine prob. diff.0.81.01.9-0.8-0.8-0.3-0.8-0.9-1.21.31.31.4-0.9-0.9
Pavlov. Cond. response bias0.50.61.2-0.4-0.7-0.2-0.7-0.5-0.90.90.91.0-0.3-1.1
Pavlov. Cond. lever latency0.30.41.40.60.40.41.20.50.7-0.7-0.7-0.80.30.3
Pavlov. Cond. magazine entry latency0.30.51.70.9-0.9-0.7-0.80.1-0.10.10.1-0.71.3-0.5
Pavlov. Cond. change in total contacts0.71.62.8-1.7-1.1-0.8-1.3-1.2-1.41.41.41.3-1.2-0.8
Pavlov. Cond. index score0.50.72.2-0.6-1.1-1.0-1.5-0.7-0.90.90.90.40.1-0.6
Pavlov. Cond. latency score0.30.52.1-0.1-0.7-0.5-1.5-0.2-0.60.60.60.40.7-0.8
Pavlov. Cond. lever contacts0.20.41.6-0.5-0.4-0.4-1.3-0.4-0.60.60.60.6-0.1-0.2
Pavlov. Cond. magazine entry number0.30.41.30.30.80.71.10.50.7-0.6-0.6-0.3-0.10.4
Pavlov. Cond. intertrial magazine entries0.51.13.3-1.5-0.6-0.6-0.1-1.3-1.01.01.01.0-1.80.0
Pavlov. Cond. lever-magazine prob. diff.0.61.02.6-0.7-1.2-1.1-1.6-0.8-1.11.11.10.6-0.0-0.7
Pavlov. Cond. response bias0.40.61.9-0.7-0.9-0.7-1.4-0.5-0.80.80.80.50.1-0.7
Time in closed arm before self-admin0.10.20.8-0.10.50.20.4-0.30.4-0.2-0.20.1-0.90.7
Time in closed arm after self-admin2.73.04.0-2.0-1.7-1.4-1.5-2.0-1.82.02.01.7-1.8-1.0
Time in open arm before self-admin0.40.51.20.2-1.0-1.10.6-0.8-0.20.20.2-1.1-0.50.6
Time in open arm after self-admin1.21.32.71.60.70.21.10.61.1-1.2-1.2-1.50.91.5
Bone: periosteal estimation0.41.03.7-1.10.51.0-1.40.5-0.50.50.51.90.3-1.4
Bone: periosteal perimeter0.81.54.0-1.8-0.4-0.0-1.6-0.6-1.31.21.22.0-0.7-1.3
Bone: post-yield work0.30.61.7-1.3-0.6-0.7-1.3-0.5-0.70.80.80.7-0.3-0.3
Progressive ratio test 1 active lever presses0.40.63.10.90.30.2-0.70.90.7-0.6-0.6-0.61.8-0.1
Progressive ratio test 1 breakpoint0.30.63.00.80.20.2-0.80.90.7-0.5-0.5-0.61.7-0.2
Progressive ratio test 1 inactive lever presses0.20.41.31.10.81.00.60.60.6-0.4-0.40.00.4-0.2
Progressive ratio test 2 active lever presses1.62.35.72.41.41.00.71.71.4-1.4-1.4-1.42.30.7
Progressive ratio test 2 breakpoint1.82.45.82.41.41.00.71.71.5-1.5-1.5-1.42.30.7
Progressive ratio test 2 inactive lever presses0.51.52.41.21.61.40.61.61.3-1.3-1.3-0.71.40.4
Incentive Sensitization - Responses0.61.63.81.91.31.20.61.61.0-1.0-1.0-0.71.90.2
Incentive Sensitization - Breakpoint0.81.84.02.01.51.40.71.71.1-1.2-1.2-0.72.00.3
Sum of active levers in priming session hrs 5-66.86.39.43.03.12.72.62.42.8-2.9-2.9-1.71.21.6
Progressive ratio0.31.02.7-0.8-1.4-1.6-0.2-1.3-0.71.01.0-0.4-1.10.5
Food seeking constrained by brief footshock0.40.52.0-0.31.11.40.10.60.3-0.3-0.31.1-0.4-0.4
Seeking ratio, punishment vs. effort1.32.88.31.22.72.91.41.71.5-1.7-1.70.60.30.2
Retroperitoneal fat weight0.41.83.11.71.41.81.21.71.3-1.4-1.4-0.51.1-0.5
Reaction time number correct0.62.27.30.9-0.4-1.32.1-0.60.9-0.9-0.9-2.7-0.62.5
Reaction time mean minus median0.21.64.4-0.9-2.1-1.8-1.7-0.7-1.11.11.1-0.10.7-1.2
Reaction time mean minus median AUC0.10.51.9-0.4-1.3-1.4-0.7-0.6-0.60.60.6-0.50.1-0.1
Reaction time num false alarms0.61.02.5-0.9-1.6-1.6-0.4-1.5-1.00.80.8-0.0-1.10.0
Reaction time num false alarms AUC0.51.03.0-0.7-1.6-1.7-0.1-1.5-0.80.60.6-0.4-1.20.4
Reaction time trials correct on left0.62.27.30.9-0.4-1.32.1-0.60.9-0.9-0.9-2.7-0.62.5
Reaction time trials on left0.62.17.21.0-0.5-1.42.0-0.60.8-0.8-0.8-2.7-0.52.4
Reaction time mean0.20.52.70.1-0.5-0.3-0.80.80.2-0.3-0.3-0.71.6-1.0
Reaction time mean AUC0.20.62.80.2-0.20.1-0.61.00.4-0.5-0.5-0.71.7-0.9
Median of all reaction times0.50.83.40.40.10.5-0.41.30.6-0.7-0.7-0.71.9-1.0
Reaction time omissions0.50.92.7-0.0-1.6-1.4-1.2-0.3-0.70.50.5-0.41.1-1.0
Reaction time false alarm rate0.50.71.0-0.9-0.9-0.5-1.0-0.7-1.00.80.81.0-0.4-0.9
Reaction time premature initiation rate0.20.31.60.30.3-0.00.9-0.40.1-0.0-0.0-0.1-0.81.3
Reaction time premature initiations0.41.35.40.6-0.2-1.01.8-0.80.4-0.3-0.3-1.5-1.12.3
Std. dev. reaction times0.31.12.9-0.8-1.7-1.5-1.6-0.4-0.80.70.7-0.30.9-0.9
Reaction time trials completed0.62.17.21.0-0.5-1.42.0-0.60.8-0.8-0.8-2.7-0.52.4
Reaction time trials AUC0.62.06.60.7-0.9-1.81.8-1.00.5-0.5-0.5-2.6-0.72.4
Run reversals in cocaine runway, females0.30.30.6-0.2-0.3-0.60.3-0.7-0.40.60.6-0.1-0.80.7
Run reversals in cocaine runway, males0.50.61.7-0.60.10.70.3-0.3-0.60.60.61.3-1.2-0.9
Latency to leave start box in cocaine runway0.91.22.8-0.4-1.2-1.70.7-1.7-0.50.50.5-0.7-1.61.2
Latency to leave start box in cocaine runway, F1.11.43.10.1-1.2-1.80.9-1.7-0.40.40.4-1.0-1.71.5
Latency to leave start box in cocaine runway, M0.10.10.5-0.7-0.1-0.10.2-0.1-0.00.00.00.0-0.3-0.1
Std. dev. time between licks in bursts0.30.62.2-1.2-0.6-0.0-0.90.2-0.60.60.60.70.3-1.5
Total sessions with >9 infusions0.20.20.80.9-0.6-0.40.20.00.2-0.0-0.0-0.70.6-0.1
Short access day 1 total inactive lever presses0.40.82.5-1.3-0.7-0.9-0.2-1.1-0.60.70.70.4-1.60.4
Short access day 10 total inactive lever presses0.42.86.91.72.11.52.60.91.5-1.7-1.7-1.3-0.21.9
Short access day 1 total infusions0.00.10.50.0-0.20.10.7-0.00.1-0.0-0.0-0.3-0.4-0.1
Short access day 10 total infusions0.40.72.41.50.70.70.50.80.8-0.7-0.7-0.61.00.2
Short access total infusions0.50.72.51.60.70.90.70.90.8-0.7-0.7-0.61.0-0.1
Short access day 1 locomotion0.10.20.70.6-0.8-0.80.3-0.50.10.10.1-0.7-0.10.4
Short access day 10 total locomotion0.10.31.2-0.5-0.2-0.70.3-0.70.20.00.0-0.4-0.71.1
Short access total locomotion0.20.20.60.60.0-0.20.60.00.7-0.4-0.4-0.80.20.7
One hour access (0.3 mA shock)2.73.36.11.82.02.11.22.51.9-1.8-1.8-1.22.20.2
Compulsive drug intake0.50.72.8-0.10.60.51.70.40.7-0.8-0.8-0.9-0.70.8
One hour access (shock baseline)0.51.43.71.61.41.5-0.01.60.9-0.8-0.8-0.11.9-0.4
Social response proportion0.50.61.6-0.21.20.80.80.00.5-0.5-0.50.3-1.11.3
Social responses1.52.03.60.81.91.21.61.11.7-1.6-1.6-1.00.31.9
Social time0.10.20.4-0.10.60.60.70.50.5-0.4-0.4-0.20.10.2
Soleus weight0.10.41.70.6-0.40.1-0.40.5-0.10.00.00.11.2-1.3
Bone: stiffness0.30.51.3-1.00.50.9-0.90.7-0.00.10.11.10.4-1.1
Tibialis anterior weight0.20.82.6-0.3-0.8-0.5-1.6-0.2-0.90.80.81.10.8-1.2
Time to tail flick, vehicle, before self-admin0.20.31.01.00.80.60.40.10.4-0.5-0.50.1-0.40.3
Time to tail flick, vehicle, after self-admin0.10.20.40.30.60.50.6-0.10.1-0.4-0.40.0-0.50.5
Time to tail flick, test, before self-admin1.11.23.3-1.8-0.4-0.1-1.2-0.5-1.01.21.21.6-0.6-1.0
Time to tail flick, test, after self-admin0.40.41.3-0.6-0.20.2-1.00.0-0.50.50.51.00.2-1.1
Delta time to tail flick, vehicle, before/after SA1.11.22.4-1.3-1.5-1.2-1.0-0.9-1.31.11.10.6-0.3-0.9
Delta time to tail flick, test, before/after SA0.10.20.91.00.20.30.50.10.4-0.4-0.4-0.30.00.2
Tibia length0.41.04.00.41.52.00.11.30.5-0.6-0.61.10.6-0.9
Ambulatory time before self-admin0.00.10.3-0.10.60.40.10.2-0.0-0.3-0.30.4-0.10.2
Ambulatory time after self-admin0.10.10.30.0-0.3-0.5-0.5-0.3-0.30.30.30.30.2-0.2
Bone: tissue strength2.32.44.41.81.10.91.71.51.8-1.8-1.8-2.11.40.8
Total heroin consumption1.82.16.80.51.20.32.1-0.31.1-1.5-1.5-1.2-1.62.6
Bone: trabecular number0.61.22.8-0.01.61.71.41.21.2-1.2-1.2-0.4-0.20.4
Bone: trabecular spacing0.20.31.20.7-1.0-1.1-0.1-0.7-0.50.40.4-0.50.20.2
Bone: trabecular thickness0.60.82.9-1.1-0.20.5-1.20.3-0.50.60.61.40.4-1.7
Bone: trabecular tissue density2.23.86.52.12.32.41.22.52.1-2.1-2.1-1.02.2-0.0
Water consumed over 24 hours1.12.15.11.91.31.32.21.11.6-1.6-1.6-1.40.40.9
Number of responses in last shaping day2.93.76.5-2.1-1.8-1.1-2.6-1.5-2.12.02.02.3-0.9-2.1