Hub : Genes

Zfp354a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Zfp354a 0.05 0.03 2.0e-04 0.05 0.04 0.04 0.04 2.3e-06 5.8e-05 1.7e-05 1.2e-05
2 NAcc gene expression Zfp354a 0.09 0.04 2.0e-11 0.06 0.07 0.06 0.06 1.5e-09 2.5e-11 1.0e-09 6.6e-10
3 PL gene expression Zfp354a 0.06 0.04 2.3e-04 0.03 0.04 0.04 0.04 2.3e-04 1.5e-05 3.0e-05 3.6e-05
4 Liver mRNA stability Zfp354a 0.07 0.04 1.2e-04 0.01 0.03 0.03 0.03 1.8e-02 2.7e-04 1.1e-04 4.4e-04
5 Brain gene expression Zfp354a 0.09 0.04 4.3e-06 0.05 0.06 0.05 0.06 2.1e-05 1.6e-06 1.3e-05 4.4e-06
6 Brain mRNA stability Zfp354a 0.04 0.03 6.2e-03 0.01 0.01 0 0.01 3.5e-02 4.4e-02 1.9e-01 7.6e-02
7 pVTA gene expression Zfp354a 0.05 0.03 1.8e-03 0.05 0.03 0.04 0.04 9.6e-05 1.1e-03 4.6e-04 4.2e-04
8 pVTA mRNA stability Zfp354a 0.07 0.04 1.9e-04 0.05 0.04 0.04 0.05 5.1e-05 2.7e-04 2.7e-04 8.1e-05
9 Adipose mRNA stability Zfp354a 0.04 0.04 5.5e-03 0.02 0.01 0.01 0.02 3.6e-03 4.5e-02 8.6e-03 5.4e-03
10 NAcc mRNA stability Zfp354a 0.04 0.03 1.6e-04 0.02 0.03 0.03 0.03 3.8e-04 2.3e-05 2.2e-05 2.6e-05
11 IC gene expression Zfp354a 0.12 0.08 2.5e-03 0.06 0.05 0.02 0.04 1.6e-03 4.4e-03 3.3e-02 5.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.50.93.30.51.41.8-1.11.0-0.80.80.8-0.50.40.2
Area under the delay curve0.60.82.5-0.41.41.6-1.00.8-0.80.80.8-0.10.3-0.3
BMI with tail0.93.16.1-2.22.12.5-1.32.2-1.81.71.70.5-1.60.3
BMI without tail1.23.87.3-2.22.42.7-2.12.2-2.02.12.10.7-1.1-0.2
Body weight1.25.410.6-2.42.93.2-2.42.7-2.62.52.51.0-1.3-0.3
Weight adjusted by age1.21.94.4-1.70.90.5-1.31.1-1.71.31.32.1-1.1-1.2
Bone surface0.20.41.40.81.01.2-0.50.7-0.50.40.4-0.40.40.2
Bone volume0.40.72.60.61.31.6-0.40.9-0.50.50.5-0.80.20.5
Breakpoint value in progressive ratio session1.11.33.8-0.70.7-0.0-1.40.1-1.11.41.41.60.4-1.9
Number of licking bursts0.40.62.1-0.70.0-0.3-1.30.0-0.70.70.71.40.2-1.1
Context. condit. distance diff. score0.70.81.6-1.20.80.6-1.30.7-1.11.01.01.1-0.4-0.7
Locomotion velocity, session 10.10.10.3-0.5-0.20.0-0.5-0.10.10.10.10.20.10.3
Locomotion distance, session 10.50.61.7-1.3-0.4-0.3-0.40.5-0.60.40.41.3-1.30.3
Locomotion velocity, session 20.50.52.1-1.1-0.10.1-0.20.8-0.50.60.60.9-1.40.5
Locomotion distance, session 21.31.94.3-2.10.50.7-1.01.5-1.41.31.31.7-2.00.3
Locomotion velocity, session 33.74.37.8-2.81.40.9-2.31.6-2.42.22.22.8-1.4-1.7
Locomotion distance, session 32.52.74.7-2.21.41.2-1.91.5-2.01.81.81.9-1.0-0.9
Stereotopy head waving bouts, day 30.40.51.21.1-0.9-0.80.7-0.70.7-0.8-0.8-0.30.40.3
Stereotopy head waving duration, day 30.50.61.71.1-0.9-1.31.0-0.80.6-0.6-0.60.20.1-0.3
Locomotion velocity, session 70.30.31.50.6-0.00.01.20.40.1-0.2-0.2-0.5-1.00.7
Locomotion distance, session 70.10.10.60.8-0.2-0.40.7-0.00.1-0.2-0.2-0.1-0.2-0.0
Stereotopy head waving bouts, day 70.60.72.10.1-0.7-0.31.40.40.4-0.3-0.3-0.1-1.41.4
Stereotopy head waving duration, day 70.20.31.1-0.0-0.5-0.41.00.10.3-0.3-0.3-0.1-1.00.7
Locomotion velocity, session 84.35.19.3-2.41.71.4-2.62.2-2.82.62.63.1-1.7-1.0
Locomotion distance, session 82.94.28.2-2.91.61.5-2.32.0-2.42.22.22.3-1.8-0.8
Degree of sensitization distance2.52.66.22.1-1.5-1.52.5-1.21.8-1.7-1.7-1.50.21.0
Degree of sensitization stereotypy0.70.73.00.0-0.50.11.40.50.5-0.4-0.4-0.6-1.31.7
Conditioned locomotion0.20.20.60.50.20.60.60.30.2-0.0-0.0-0.8-0.10.8
Cocaine response after cond. corrected0.50.71.71.1-0.20.31.20.10.6-0.6-0.6-1.2-0.21.3
Cocaine response after cond. not corrected0.81.02.31.2-0.5-0.01.5-0.20.9-0.9-0.9-1.5-0.11.4
Cocaine response before conditioning0.10.10.3-0.50.40.40.00.4-0.20.20.2-0.2-0.50.1
Saline control response0.10.10.50.70.00.00.60.10.2-0.1-0.1-0.3-0.10.3
Bone: connectivity density0.20.21.31.10.30.4-0.60.2-0.30.20.20.20.7-0.2
Bone: cortical apparent density0.20.30.80.6-0.7-0.90.0-0.80.4-0.4-0.40.20.8-0.4
Bone: cortical area1.21.96.7-0.42.22.6-0.71.8-1.21.21.2-0.7-0.60.6
Bone: cortical porosity2.42.66.5-1.51.92.50.12.3-1.21.11.1-0.7-2.11.5
Bone: cortical porosity1.92.05.8-0.91.72.40.52.0-0.80.70.7-1.2-1.71.6
Bone: cortical thickness2.54.29.1-1.52.93.0-2.32.3-2.22.22.20.6-0.6-0.5
Bone: cortical thickness2.83.38.5-1.32.92.7-1.62.0-1.91.91.90.2-0.6-0.9
Bone: cortical tissue density0.30.41.10.6-0.8-1.00.1-0.90.5-0.5-0.50.30.8-0.4
Condit. Reinf. active minus inactive responses1.01.23.60.1-1.4-0.61.2-0.61.2-1.1-1.1-0.9-0.21.9
Condit. Reinf. active-inactive response ratio0.50.51.4-0.4-1.2-1.00.9-0.50.7-0.5-0.50.1-0.60.7
Condit. Reinf. active responses1.62.03.10.8-1.6-0.81.4-1.21.7-1.7-1.7-1.60.71.8
Condit. Reinf. inactive responses0.91.13.21.1-0.10.20.4-0.90.9-1.1-1.1-1.81.70.5
Incentive salience index mean0.30.41.7-0.4-0.8-0.20.5-0.20.6-0.5-0.5-0.4-0.21.3
Condit. Reinf. lever presses0.10.10.5-0.70.10.4-0.20.2-0.10.10.1-0.0-0.20.4
Condit. Reinf. active minus inactive responses2.83.76.32.1-1.5-0.82.5-1.32.1-2.2-2.2-2.50.92.0
Condit. Reinf. active-inactive response ratio2.02.44.82.2-1.1-0.81.5-1.41.6-1.7-1.7-1.91.50.9
Condit. Reinf. active responses2.73.86.72.5-1.6-1.22.6-1.52.1-2.2-2.2-2.21.11.5
Condit. Reinf. inactive responses0.30.50.90.9-0.5-0.60.9-0.60.7-0.8-0.8-0.60.60.1
Condit. Reinf. lever presses2.23.04.02.0-1.7-1.71.8-2.01.9-2.0-2.0-1.41.70.4
Condit. Reinf. lever reinforcers received3.14.37.22.6-1.8-1.42.7-1.72.3-2.4-2.4-2.31.21.6
Conditioned reinforcement - actives0.20.41.1-1.0-0.7-0.90.0-0.1-0.00.00.00.9-1.0-0.2
Conditioned reinforcement - inactives0.10.10.3-0.20.40.5-0.3-0.0-0.10.10.1-0.30.40.1
Conditioned locomotion0.30.40.6-0.0-0.7-0.50.7-0.50.7-0.8-0.8-0.7-0.30.7
Patch foraging indifference point 0 sec0.61.14.71.0-0.4-0.8-0.3-1.50.8-0.7-0.7-0.62.2-1.0
Patch foraging indifference point AUC1.72.45.72.4-1.1-0.32.1-0.41.4-1.3-1.3-2.00.22.4
Delay disc. indifference point, 0s delay1.41.53.1-1.11.51.2-1.81.1-1.31.21.21.1-0.2-1.3
Delay disc. indifference point, 16s delay1.21.32.9-1.01.71.7-1.60.9-1.21.01.00.30.3-0.7
Delay disc. indifference point, 2s delay0.70.82.3-0.81.21.5-1.10.9-0.90.90.90.10.1-0.1
Delay disc. indifference point, 24s delay1.01.12.4-0.91.61.4-1.21.0-1.21.11.10.5-0.1-0.7
Delay disc. indifference point, 4s delay0.80.92.91.20.10.40.5-0.50.9-0.9-0.9-1.71.20.7
Delay disc. indifference point, 8s delay0.30.30.8-0.10.70.8-0.90.1-0.40.50.50.00.7-0.4
Indifference point function ln k0.61.03.1-1.81.31.1-1.10.7-0.80.80.80.3-0.3-1.0
Indifference point function log k0.61.03.1-1.81.31.1-1.10.7-0.80.80.80.3-0.3-1.0
Patch foraging total patch changes 0 sec0.81.55.71.5-0.5-0.8-0.0-1.61.1-1.0-1.0-1.12.4-0.7
Patch foraging total patch changes 12 sec3.54.69.93.1-2.3-2.31.4-2.52.3-2.0-2.0-1.42.40.5
Patch foraging total patch changes 18 sec0.30.42.41.50.10.2-0.3-0.20.2-0.0-0.0-0.51.40.2
Patch foraging total patch changes 24 sec1.42.36.12.5-1.3-1.11.0-1.51.5-1.6-1.6-1.51.80.9
Patch foraging total patch changes 6 sec1.62.55.82.4-1.6-1.60.9-1.81.7-1.6-1.6-1.21.70.5
Patch foraging time to switch 0 sec0.20.42.0-0.5-0.4-0.8-0.6-0.1-0.40.40.41.4-0.3-0.8
Patch foraging water rate 0 sec0.30.71.50.8-0.6-0.30.2-1.01.0-0.9-0.9-1.21.20.5
Patch foraging water rate 12 sec0.30.61.6-0.51.21.3-1.10.7-0.80.70.70.10.2-0.4
Patch foraging water rate 18 sec0.40.63.10.50.30.1-0.6-0.90.5-0.5-0.5-0.91.8-0.6
Patch foraging water rate 24 sec0.40.61.50.6-0.5-0.80.2-1.20.8-0.7-0.7-0.51.2-0.6
Patch foraging water rate 6 sec0.30.41.5-1.00.70.8-1.20.4-0.60.50.50.20.1-0.4
Seeking ratio, delayed vs. immediate footshock1.21.43.6-1.91.21.0-1.21.2-1.31.21.20.9-1.0-0.6
Distance traveled before self-admin0.10.20.80.40.30.20.6-0.00.4-0.2-0.2-0.90.00.1
Distance traveled after self-admin0.30.31.0-0.20.30.40.80.40.3-0.3-0.3-1.0-0.80.8
Extensor digitorum longus weight0.10.42.0-0.6-0.6-0.40.70.30.2-0.1-0.1-0.0-1.40.9
Bone: elastic displacement0.40.51.7-1.30.80.9-0.80.7-0.50.60.60.2-0.60.0
Bone: elastic work4.05.39.6-2.53.12.6-2.81.9-2.42.52.51.3-0.5-2.0
Bone: endosteal estimation1.22.66.92.0-1.0-0.52.6-0.71.7-1.6-1.6-2.30.11.7
Bone: endosteal perimeter2.04.38.52.5-1.6-0.82.9-1.12.2-2.2-2.2-2.70.42.5
Epididymis fat weight0.31.22.6-1.31.51.6-1.11.1-1.21.11.10.2-0.3-0.3
Delta time in closed arm before/after self-admin2.32.23.21.4-1.8-1.21.2-1.31.8-1.8-1.8-1.20.71.7
Delta time in open arm before/after self-admin0.80.81.5-1.11.01.0-0.21.1-0.80.90.90.3-1.2-0.3
Diff in mean of infusions in LGA sessions1.92.47.8-0.70.1-0.8-2.3-1.5-0.60.60.61.52.5-2.8
Delay discount exponential model param0.60.72.50.3-1.4-1.60.8-0.80.8-0.7-0.70.3-0.20.1
Extinction: sum of active levers before priming4.95.47.9-2.42.72.2-2.81.9-2.62.82.82.0-0.6-1.8
Active lever presses in extinction session 60.10.10.30.0-0.4-0.5-0.1-0.50.30.20.20.20.3-0.1
Bone: final force0.81.33.4-0.31.41.90.41.7-0.80.80.8-0.7-1.51.2
Bone: final moment1.01.63.8-0.61.51.9-0.11.9-1.11.11.1-0.3-1.61.0
Food consumed during 24 hour testing period0.91.25.1-1.00.70.8-2.30.7-1.11.11.11.30.3-0.6
Glucose0.20.31.0-0.20.70.4-0.8-0.1-0.40.30.3-0.01.0-1.0
Heart weight5.38.110.8-3.33.13.1-2.83.3-3.23.23.22.1-2.4-0.8
Delay discount hyperbolic model param0.60.72.30.3-1.4-1.50.8-0.80.8-0.7-0.70.2-0.30.2
Intermittent access intake day 1-15 change0.10.20.9-1.00.30.40.40.2-0.00.10.1-0.4-0.90.4
Intermittent access intake escalation0.10.21.0-1.00.40.40.10.0-0.00.10.1-0.5-0.40.0
Intermittent access intake escalation 20.20.20.7-0.30.60.80.10.40.0-0.0-0.0-0.8-0.30.5
Intermitt. access day 1 inactive lever presses0.41.43.8-1.91.10.7-1.00.8-1.41.21.21.1-0.8-1.1
Intermitt. access day 15 inactive lever presses0.30.61.2-0.81.10.7-0.70.6-0.90.80.80.6-0.3-0.9
Intermitt. access escalation Index0.10.20.70.3-0.4-0.00.60.20.6-0.1-0.1-0.2-0.50.9
Intermittent access day 1 total infusions0.40.61.9-1.00.50.4-0.11.0-0.80.70.70.8-1.4-0.0
Intermittent access day 15 total infusions0.60.94.0-2.00.80.9-0.20.9-0.70.70.70.4-1.5-0.0
Intermittent access terminal intake (last 3 days)1.11.53.7-1.91.31.7-0.21.5-0.80.70.7-0.1-1.80.6
Intermittent access total infusions0.91.13.1-1.80.91.1-0.51.3-0.80.80.80.5-1.60.3
Intermittent access day 1 locomotion0.20.21.2-0.4-0.2-0.10.30.4-0.30.20.20.6-1.10.2
Intermittent access day 15 total locomotion0.50.82.80.4-0.8-0.61.7-0.00.7-0.8-0.8-0.8-1.31.1
Intermittent access total locomotion0.60.71.8-0.3-0.9-0.71.3-0.00.6-0.7-0.7-0.4-1.31.1
Intermittent access standard deviation2.75.612.1-2.83.33.5-2.32.7-2.22.22.20.6-1.7-0.4
Left kidney weight1.88.212.9-3.62.82.7-2.53.0-3.33.43.42.4-2.5-1.1
Right kidney weight1.46.410.9-3.32.12.2-2.52.7-2.82.92.92.4-2.5-0.5
Cocaine induced anxiety0.40.61.60.11.31.1-0.21.1-0.70.80.8-0.0-0.6-0.1
Post-drug Anxiety0.50.52.31.5-0.1-0.40.9-0.50.6-0.6-0.6-0.80.7-0.1
Baseline Anxiety3.74.27.21.7-2.7-2.71.6-2.62.2-2.3-2.3-0.91.80.4
Tail length0.41.43.4-0.61.41.5-1.91.2-1.21.41.40.7-0.0-0.3
Length with tail0.41.83.8-0.81.71.5-1.91.1-1.51.61.60.90.0-1.0
Length without tail0.10.40.8-0.30.90.8-0.80.6-0.90.60.60.30.1-0.7
Times rat made contact with spout0.50.62.1-0.9-0.2-0.4-1.4-0.2-0.50.50.51.40.2-0.8
Lifetime Intake1.72.15.4-2.31.31.5-1.01.7-1.41.31.30.9-1.80.1
Liver weight, left3.86.311.4-2.93.22.8-3.42.0-2.72.62.61.5-0.4-2.0
Liver weight, right7.312.728.6-4.14.85.3-2.64.4-3.63.63.60.5-2.70.2
Locomotor activity0.40.61.8-0.31.01.30.50.8-0.00.10.1-1.3-0.60.8
Locomotor testing distance0.20.41.40.2-0.10.00.8-0.50.7-0.6-0.6-1.20.30.4
Locomotor testing rearing0.30.61.91.1-0.10.20.8-0.50.8-0.7-0.7-1.40.80.5
Locomotion in novel chamber1.21.53.7-0.1-1.9-1.80.7-1.71.4-1.3-1.3-0.50.80.4
Locomotion in novel chamber post-restriction1.93.15.02.2-2.1-1.42.0-1.42.0-1.8-1.8-1.51.01.7
Fecal boli incidents, locomotor time 10.40.61.8-0.40.91.3-0.01.2-0.30.50.5-0.6-0.81.2
Change in fecal boli incidents, locomotor task0.20.20.6-0.00.60.7-0.70.1-0.20.40.4-0.20.4-0.3
Time >=10cm from walls, locomotor time 10.91.02.51.5-0.10.21.3-0.50.7-1.0-1.0-1.60.80.7
Bouts of movement, locomotor time 10.20.20.80.00.80.9-0.30.20.0-0.1-0.1-0.80.5-0.0
Total resting periods, locomotor time 10.40.41.6-0.21.31.2-0.70.5-0.40.30.3-0.40.5-0.5
Rest time, locomotor task time 10.81.02.6-0.41.61.2-0.51.4-1.11.11.10.4-0.9-0.7
Distance moved, locomotor task time 10.30.51.60.6-0.7-0.9-0.0-1.10.5-0.4-0.40.01.3-0.6
Vertical activity count, locomotor time 10.20.41.00.0-1.0-1.00.5-1.00.7-0.5-0.5-0.20.30.0
Time >=10cm from walls, locomotor time 20.30.42.20.40.20.60.4-0.30.6-0.5-0.5-1.50.70.7
Bouts of movement, locomotor time 20.40.62.71.00.1-0.4-0.4-0.90.3-0.3-0.3-0.21.6-1.1
Total resting periods, locomotor time 20.30.62.50.90.1-0.4-0.4-0.90.3-0.2-0.2-0.21.6-1.2
Rest time, locomotor task time 20.40.51.5-0.21.21.2-0.11.0-0.40.40.4-0.3-0.60.1
Distance moved, locomotor task time 20.80.93.00.3-1.5-1.7-0.0-1.40.6-0.5-0.50.71.0-0.6
Vertical activity count, locomotor time 20.30.52.0-0.1-1.3-1.40.3-0.70.3-0.0-0.00.9-0.2-0.2
Light reinforcement 10.10.20.6-0.1-0.5-0.3-0.7-0.60.4-0.4-0.40.10.8-0.0
Light reinforcement 20.20.21.0-0.50.20.1-0.7-0.60.0-0.2-0.2-0.21.0-0.6
Bone: marrow area1.22.56.91.9-1.0-0.62.6-0.71.6-1.6-1.6-2.20.01.7
Bone: maximum diameter0.40.82.70.70.41.01.10.50.4-0.4-0.4-1.7-0.41.5
Bone: maximum force0.81.43.6-0.41.81.9-0.11.8-1.21.11.1-0.3-1.20.4
Bone: maximum moment1.01.83.9-0.81.92.0-0.51.9-1.51.41.40.2-1.30.1
Mean time between licks in bursts0.30.83.0-0.0-1.5-1.70.3-1.10.7-0.7-0.70.80.2-0.4
Mean num. licks in bursts0.10.10.30.3-0.2-0.00.3-0.30.4-0.4-0.4-0.60.30.3
Cd content in liver3.33.75.62.1-2.3-2.11.0-2.42.2-2.2-2.2-1.22.10.5
Co content in liver0.10.10.3-0.50.20.3-0.10.3-0.10.10.1-0.1-0.50.3
Cu content in liver2.12.54.80.9-1.4-1.21.5-1.82.0-1.9-1.9-2.21.30.7
Fe content in liver1.11.32.0-1.31.11.0-1.41.1-1.41.21.21.2-0.5-0.7
K content in liver0.40.41.7-0.8-0.30.30.20.6-0.10.10.10.1-1.11.3
Mg content in liver1.01.02.30.8-1.5-1.01.1-0.71.2-1.0-1.0-0.6-0.01.5
Mn content in liver1.21.43.61.0-0.8-0.11.3-0.71.3-1.3-1.3-1.90.71.6
Na content in liver0.50.51.0-0.80.60.4-0.90.5-0.90.70.71.0-0.2-0.7
Rb content in liver0.40.41.10.5-1.0-0.90.9-0.40.7-0.4-0.4-0.1-0.40.8
Se content in liver0.50.72.3-1.00.20.1-1.50.3-0.70.80.81.3-0.0-0.6
Sr content in liver0.50.41.60.3-0.4-0.6-0.7-0.90.3-0.3-0.30.31.3-0.8
Zn content in liver0.30.30.80.6-0.9-0.60.4-0.50.7-0.6-0.6-0.40.20.7
Bone: minimum diameter0.20.41.31.10.60.90.40.6-0.10.10.1-0.90.00.7
Time in familiar zone, hab. session 10.40.31.40.50.91.20.10.4-0.10.00.0-1.00.30.4
Time in novel zone, hab. session 10.60.62.4-0.70.50.60.21.2-0.80.70.70.6-1.60.4
Total zone transitions, hab. session 10.81.14.3-1.3-1.3-0.80.40.5-0.10.10.11.3-2.11.3
Total locomotion distance, hab. session 10.50.72.5-0.90.30.70.11.2-0.70.60.60.5-1.60.8
Locomotion velocity, hab. session 10.60.92.0-1.40.40.4-0.61.0-1.00.90.91.2-1.40.1
Time in familiar zone, hab. session 22.93.08.7-1.32.63.0-0.92.3-1.61.71.7-0.3-1.20.5
Time in novel zone, hab. session 20.70.72.00.8-1.2-1.40.4-1.00.7-0.8-0.80.30.6-0.3
Total zone transitions, hab. session 21.62.07.3-1.8-0.10.3-0.41.6-1.21.21.21.9-2.71.0
Total locomotion distance, hab. session 21.21.54.1-1.60.20.5-0.61.4-1.21.21.21.6-2.00.7
Locomotion velocity, hab. session 21.41.84.0-1.80.30.4-0.91.4-1.41.41.41.9-2.00.3
Novel to familiar place preference ratio1.01.12.21.1-1.3-1.01.5-0.71.1-1.1-1.1-0.8-0.11.0
Novelty place preference0.60.61.50.9-0.9-0.71.2-0.40.9-0.8-0.8-0.7-0.20.8
Time in novel zone, NPP test0.50.51.40.9-0.7-0.61.2-0.20.7-0.7-0.7-0.6-0.30.8
Total zone transitions, NPP test0.40.61.5-0.4-1.2-0.90.60.10.2-0.2-0.20.8-1.21.0
Total locomotion distance, NPP test0.30.42.1-0.80.10.20.30.8-0.50.40.40.5-1.50.5
Locomotion velocity, NPP test0.20.31.4-0.6-0.5-0.30.90.20.2-0.2-0.2-0.0-1.20.9
Intraocular pressure0.10.10.4-0.1-0.4-0.6-0.3-0.30.1-0.2-0.20.5-0.0-0.4
Delta distance traveled before/after self-admin0.10.20.40.2-0.5-0.20.1-0.30.4-0.6-0.6-0.40.20.6
Delta ambulatory time before/after self-admin0.81.01.70.7-1.3-0.91.2-0.81.0-1.3-1.3-0.90.11.1
Parametrial fat weight0.10.32.40.0-0.30.60.00.40.2-0.1-0.1-0.4-0.31.6
Pavlov. Cond. lever latency0.20.31.01.0-0.6-0.50.7-0.20.3-0.4-0.4-0.2-0.00.5
Pavlov. Cond. magazine entry latency0.81.02.80.8-0.30.40.9-0.31.0-1.1-1.1-1.70.41.6
Pavlov. Cond. change in total contacts1.21.22.00.9-1.1-0.71.1-1.01.3-1.4-1.4-1.30.81.0
Pavlov. Cond. index score0.30.41.10.3-0.40.00.5-0.40.8-0.8-0.8-1.10.40.8
Pavlov. Cond. latency score0.10.10.5-0.20.10.40.0-0.10.3-0.3-0.3-0.70.40.4
Pavlov. Cond. lever contacts0.00.10.4-0.60.00.0-0.2-0.20.2-0.0-0.0-0.20.2-0.1
Pavlov. Cond. magazine entry number1.51.92.9-1.41.20.6-1.60.9-1.61.71.71.7-0.6-1.7
Pavlov. Cond. intertrial magazine entries4.35.111.52.0-3.4-2.92.0-2.22.4-2.6-2.6-0.80.81.7
Pavlov. Cond. lever-magazine prob. diff.0.81.01.90.8-0.8-0.30.8-0.91.2-1.3-1.3-1.40.90.9
Pavlov. Cond. response bias0.50.61.20.4-0.7-0.20.7-0.50.9-0.9-0.9-1.00.31.1
Pavlov. Cond. lever latency0.30.41.4-0.60.40.4-1.20.5-0.70.70.70.8-0.3-0.3
Pavlov. Cond. magazine entry latency0.40.51.7-0.9-0.9-0.70.80.10.1-0.1-0.10.7-1.30.5
Pavlov. Cond. change in total contacts1.01.62.81.7-1.1-0.81.3-1.21.4-1.4-1.4-1.31.20.8
Pavlov. Cond. index score0.50.72.20.6-1.1-1.01.5-0.70.9-0.9-0.9-0.4-0.10.6
Pavlov. Cond. latency score0.40.52.10.1-0.7-0.51.5-0.20.6-0.6-0.6-0.4-0.70.8
Pavlov. Cond. lever contacts0.30.41.60.5-0.4-0.41.3-0.40.6-0.6-0.6-0.60.10.2
Pavlov. Cond. magazine entry number0.30.41.3-0.30.80.7-1.10.5-0.70.60.60.30.1-0.4
Pavlov. Cond. intertrial magazine entries0.71.13.31.5-0.6-0.60.1-1.31.0-1.0-1.0-1.01.8-0.0
Pavlov. Cond. lever-magazine prob. diff.0.71.02.60.7-1.2-1.11.6-0.81.1-1.1-1.1-0.60.00.7
Pavlov. Cond. response bias0.40.61.90.7-0.9-0.71.4-0.50.8-0.8-0.8-0.5-0.10.7
Time in closed arm before self-admin0.10.20.80.10.50.2-0.4-0.3-0.40.20.2-0.10.9-0.7
Time in closed arm after self-admin2.83.04.02.0-1.7-1.41.5-2.01.8-2.0-2.0-1.71.81.0
Time in open arm before self-admin0.40.51.2-0.2-1.0-1.1-0.6-0.80.2-0.2-0.21.10.5-0.6
Time in open arm after self-admin1.21.32.7-1.60.70.2-1.10.6-1.11.21.21.5-0.9-1.5
Bone: periosteal estimation0.51.03.71.10.51.01.40.50.5-0.5-0.5-1.9-0.31.4
Bone: periosteal perimeter0.91.54.01.8-0.4-0.01.6-0.61.3-1.2-1.2-2.00.71.3
Bone: post-yield work0.40.61.71.3-0.6-0.71.3-0.50.7-0.8-0.8-0.70.30.3
Progressive ratio test 1 active lever presses0.50.63.1-0.90.30.20.70.9-0.70.60.60.6-1.80.1
Progressive ratio test 1 breakpoint0.50.63.0-0.80.20.20.80.9-0.70.50.50.6-1.70.2
Progressive ratio test 1 inactive lever presses0.30.41.3-1.10.81.0-0.60.6-0.60.40.4-0.0-0.40.2
Progressive ratio test 2 active lever presses2.02.35.7-2.41.41.0-0.71.7-1.41.41.41.4-2.3-0.7
Progressive ratio test 2 breakpoint2.12.45.8-2.41.41.0-0.71.7-1.51.51.51.4-2.3-0.7
Progressive ratio test 2 inactive lever presses0.91.52.4-1.21.61.4-0.61.6-1.31.31.30.7-1.4-0.4
Incentive Sensitization - Responses1.11.63.8-1.91.31.2-0.61.6-1.01.01.00.7-1.9-0.2
Incentive Sensitization - Breakpoint1.41.84.0-2.01.51.4-0.71.7-1.11.21.20.7-2.0-0.3
Sum of active levers in priming session hrs 5-66.86.39.4-3.03.12.7-2.62.4-2.82.92.91.7-1.2-1.6
Progressive ratio0.61.02.70.8-1.4-1.60.2-1.30.7-1.0-1.00.41.1-0.5
Food seeking constrained by brief footshock0.40.52.00.31.11.4-0.10.6-0.30.30.3-1.10.40.4
Seeking ratio, punishment vs. effort1.92.88.3-1.22.72.9-1.41.7-1.51.71.7-0.6-0.3-0.2
Retroperitoneal fat weight0.41.83.1-1.71.41.8-1.21.7-1.31.41.40.5-1.10.5
Reaction time number correct1.12.27.3-0.9-0.4-1.3-2.1-0.6-0.90.90.92.70.6-2.5
Reaction time mean minus median0.61.64.40.9-2.1-1.81.7-0.71.1-1.1-1.10.1-0.71.2
Reaction time mean minus median AUC0.20.51.90.4-1.3-1.40.7-0.60.6-0.6-0.60.5-0.10.1
Reaction time num false alarms0.71.02.50.9-1.6-1.60.4-1.51.0-0.8-0.80.01.1-0.0
Reaction time num false alarms AUC0.71.03.00.7-1.6-1.70.1-1.50.8-0.6-0.60.41.2-0.4
Reaction time trials correct on left1.12.27.3-0.9-0.4-1.3-2.1-0.6-0.90.90.92.70.6-2.5
Reaction time trials on left1.12.17.2-1.0-0.5-1.4-2.0-0.6-0.80.80.82.70.5-2.4
Reaction time mean0.30.52.7-0.1-0.5-0.30.80.8-0.20.30.30.7-1.61.0
Reaction time mean AUC0.40.62.8-0.2-0.20.10.61.0-0.40.50.50.7-1.70.9
Median of all reaction times0.60.83.4-0.40.10.50.41.3-0.60.70.70.7-1.91.0
Reaction time omissions0.60.92.70.0-1.6-1.41.2-0.30.7-0.5-0.50.4-1.11.0
Reaction time false alarm rate0.50.71.00.9-0.9-0.51.0-0.71.0-0.8-0.8-1.00.40.9
Reaction time premature initiation rate0.20.31.6-0.30.3-0.0-0.9-0.4-0.10.00.00.10.8-1.3
Reaction time premature initiations0.71.35.4-0.6-0.2-1.0-1.8-0.8-0.40.30.31.51.1-2.3
Std. dev. reaction times0.61.12.90.8-1.7-1.51.6-0.40.8-0.7-0.70.3-0.90.9
Reaction time trials completed1.12.17.2-1.0-0.5-1.4-2.0-0.6-0.80.80.82.70.5-2.4
Reaction time trials AUC1.12.06.6-0.7-0.9-1.8-1.8-1.0-0.50.50.52.60.7-2.4
Run reversals in cocaine runway, females0.30.30.60.2-0.3-0.6-0.3-0.70.4-0.6-0.60.10.8-0.7
Run reversals in cocaine runway, males0.60.61.70.60.10.7-0.3-0.30.6-0.6-0.6-1.31.20.9
Latency to leave start box in cocaine runway1.01.22.80.4-1.2-1.7-0.7-1.70.5-0.5-0.50.71.6-1.2
Latency to leave start box in cocaine runway, F1.21.43.1-0.1-1.2-1.8-0.9-1.70.4-0.4-0.41.01.7-1.5
Latency to leave start box in cocaine runway, M0.10.10.50.7-0.1-0.1-0.2-0.10.0-0.0-0.0-0.00.30.1
Std. dev. time between licks in bursts0.40.62.21.2-0.6-0.00.90.20.6-0.6-0.6-0.7-0.31.5
Total sessions with >9 infusions0.20.20.8-0.9-0.6-0.4-0.20.0-0.20.00.00.7-0.60.1
Short access day 1 total inactive lever presses0.60.82.51.3-0.7-0.90.2-1.10.6-0.7-0.7-0.41.6-0.4
Short access day 10 total inactive lever presses1.22.86.9-1.72.11.5-2.60.9-1.51.71.71.30.2-1.9
Short access day 1 total infusions0.10.10.5-0.0-0.20.1-0.7-0.0-0.10.00.00.30.40.1
Short access day 10 total infusions0.50.72.4-1.50.70.7-0.50.8-0.80.70.70.6-1.0-0.2
Short access total infusions0.60.72.5-1.60.70.9-0.70.9-0.80.70.70.6-1.00.1
Short access day 1 locomotion0.20.20.7-0.6-0.8-0.8-0.3-0.5-0.1-0.1-0.10.70.1-0.4
Short access day 10 total locomotion0.20.31.20.5-0.2-0.7-0.3-0.7-0.2-0.0-0.00.40.7-1.1
Short access total locomotion0.20.20.6-0.60.0-0.2-0.60.0-0.70.40.40.8-0.2-0.7
One hour access (0.3 mA shock)2.83.36.1-1.82.02.1-1.22.5-1.91.81.81.2-2.2-0.2
Compulsive drug intake0.60.72.80.10.60.5-1.70.4-0.70.80.80.90.7-0.8
One hour access (shock baseline)0.91.43.7-1.61.41.50.01.6-0.90.80.80.1-1.90.4
Social response proportion0.50.61.60.21.20.8-0.80.0-0.50.50.5-0.31.1-1.3
Social responses1.52.03.6-0.81.91.2-1.61.1-1.71.61.61.0-0.3-1.9
Social time0.10.20.40.10.60.6-0.70.5-0.50.40.40.2-0.1-0.2
Soleus weight0.10.41.7-0.6-0.40.10.40.50.1-0.0-0.0-0.1-1.21.3
Bone: stiffness0.30.51.31.00.50.90.90.70.0-0.1-0.1-1.1-0.41.1
Tibialis anterior weight0.20.82.60.3-0.8-0.51.6-0.20.9-0.8-0.8-1.1-0.81.2
Time to tail flick, vehicle, before self-admin0.30.31.0-1.00.80.6-0.40.1-0.40.50.5-0.10.4-0.3
Time to tail flick, vehicle, after self-admin0.10.20.4-0.30.60.5-0.6-0.1-0.10.40.4-0.00.5-0.5
Time to tail flick, test, before self-admin1.21.23.31.8-0.4-0.11.2-0.51.0-1.2-1.2-1.60.61.0
Time to tail flick, test, after self-admin0.40.41.30.6-0.20.21.00.00.5-0.5-0.5-1.0-0.21.1
Delta time to tail flick, vehicle, before/after SA1.21.22.41.3-1.5-1.21.0-0.91.3-1.1-1.1-0.60.30.9
Delta time to tail flick, test, before/after SA0.20.20.9-1.00.20.3-0.50.1-0.40.40.40.3-0.0-0.2
Tibia length0.41.04.0-0.41.52.0-0.11.3-0.50.60.6-1.1-0.60.9
Ambulatory time before self-admin0.10.10.30.10.60.4-0.10.20.00.30.3-0.40.1-0.2
Ambulatory time after self-admin0.10.10.3-0.0-0.3-0.50.5-0.30.3-0.3-0.3-0.3-0.20.2
Bone: tissue strength2.42.44.4-1.81.10.9-1.71.5-1.81.81.82.1-1.4-0.8
Total heroin consumption1.82.16.8-0.51.20.3-2.1-0.3-1.11.51.51.21.6-2.6
Bone: trabecular number0.71.22.80.01.61.7-1.41.2-1.21.21.20.40.2-0.4
Bone: trabecular spacing0.30.31.2-0.7-1.0-1.10.1-0.70.5-0.4-0.40.5-0.2-0.2
Bone: trabecular thickness0.70.82.91.1-0.20.51.20.30.5-0.6-0.6-1.4-0.41.7
Bone: trabecular tissue density2.63.86.5-2.12.32.4-1.22.5-2.12.12.11.0-2.20.0
Water consumed over 24 hours1.62.15.1-1.91.31.3-2.21.1-1.61.61.61.4-0.4-0.9
Number of responses in last shaping day3.43.76.52.1-1.8-1.12.6-1.52.1-2.0-2.0-2.30.92.1