Hub : Genes

Zfp329

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Zfp329 0.3 0.14 5.6e-03 0 0.03 0.02 -0 1.9e-01 7.1e-03 3.5e-02 6.6e-01
2 PL mRNA stability Zfp329 0.19 0.09 2.2e-05 0.01 0.03 0.03 0.02 5.1e-02 5.1e-04 8.8e-04 2.8e-03
3 NAcc mRNA stability Zfp329 0.26 0.1 9.0e-15 0.07 0.1 0.09 0.07 7.5e-11 4.2e-15 5.5e-14 2.0e-11
4 Eye intron excision ratio chr1_82483925_82493934 0.42 0.28 7.4e-03 0.08 0.03 -0.01 0.04 2.3e-02 1.2e-01 6.1e-01 9.8e-02
5 Adipose gene expression Zfp329 0.06 0.04 5.5e-05 0.03 0.03 0.02 0.02 1.7e-04 7.3e-04 4.3e-03 1.5e-03
6 Liver mRNA stability Zfp329 0.16 0.09 1.8e-06 0.04 0.03 0.02 0.04 3.7e-05 2.6e-04 1.6e-03 2.7e-05
7 Adipose mRNA stability Zfp329 0.15 0.07 3.3e-09 0.06 0.06 0.06 0.06 4.0e-07 3.0e-07 4.9e-07 6.3e-07
8 Brain intron excision ratio chr1_82483925_82493934 0.02 0.02 5.7e-03 0.01 0 0 0.02 7.8e-02 1.5e-01 2.6e-01 2.3e-03
9 Brain intron excision ratio chr1_82413569_82418598 0.07 0.07 6.7e-03 0.01 0.03 0.03 0.03 4.1e-02 2.0e-03 7.7e-04 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.32.91.70.2-0.00.20.0-0.2-0.00.00.0
Area under the delay curve1.11.22.30.11.51.5-0.80.91.51.21.1-0.4
BMI with tail0.31.13.4-0.10.20.8-1.41.61.81.30.00.0
BMI without tail0.10.43.0-1.70.20.30.00.00.40.10.00.0
Body weight0.52.04.8-1.7-0.3-1.02.2-1.9-1.7-1.60.00.0
Weight adjusted by age0.40.61.41.20.90.51.1-0.7-0.8-0.4-0.70.2
Bone surface1.52.76.01.1-0.8-1.72.1-2.2-2.4-2.10.00.0
Bone volume1.32.34.21.0-1.0-1.81.9-2.0-2.0-2.00.00.0
Breakpoint value in progressive ratio session1.31.67.7-2.80.81.0-0.90.71.01.01.2-0.2
Number of licking bursts0.10.21.2-1.1-0.4-0.3-0.1-0.10.2-0.20.00.0
Context. condit. distance diff. score0.30.41.71.31.00.80.10.3-0.30.50.00.0
Locomotion velocity, session 10.60.62.00.91.40.81.0-0.7-0.8-0.10.00.0
Locomotion distance, session 11.51.95.70.81.60.42.4-2.0-1.7-1.00.00.0
Locomotion velocity, session 20.20.21.31.10.60.40.3-0.1-0.40.10.00.0
Locomotion distance, session 20.81.22.70.3-0.1-0.81.6-1.6-1.6-1.40.00.0
Locomotion velocity, session 30.10.10.20.3-0.4-0.5-0.1-0.0-0.4-0.20.00.0
Locomotion distance, session 31.11.28.62.90.80.20.6-0.2-1.2-0.10.00.0
Stereotopy head waving bouts, day 30.50.54.6-2.1-0.10.1-0.0-0.10.50.00.00.0
Stereotopy head waving duration, day 30.60.76.4-2.5-0.10.10.1-0.20.50.00.00.0
Locomotion velocity, session 70.10.10.4-0.20.1-0.20.6-0.6-0.6-0.40.00.0
Locomotion distance, session 70.00.00.10.20.40.20.4-0.3-0.2-0.10.00.0
Stereotopy head waving bouts, day 70.30.40.9-0.0-0.9-0.90.3-0.5-0.9-0.60.00.0
Stereotopy head waving duration, day 70.20.20.4-0.3-0.5-0.60.4-0.5-0.6-0.50.00.0
Locomotion velocity, session 80.10.20.70.40.90.50.5-0.3-0.30.00.00.0
Locomotion distance, session 80.40.52.21.51.00.40.7-0.4-1.0-0.10.00.0
Degree of sensitization distance0.50.54.1-2.00.20.30.1-0.20.6-0.00.00.0
Degree of sensitization stereotypy0.50.53.11.8-0.6-0.7-0.00.0-1.0-0.20.00.0
Conditioned locomotion0.20.31.40.21.20.90.3-0.0-0.00.40.00.0
Cocaine response after cond. corrected1.61.96.1-2.3-2.5-1.5-1.50.70.6-0.20.00.0
Cocaine response after cond. not corrected1.01.13.2-1.7-1.8-1.5-0.0-0.6-0.5-1.00.00.0
Cocaine response before conditioning2.53.08.91.61.50.13.0-2.4-2.2-1.50.00.0
Saline control response0.60.84.72.20.90.30.7-0.4-0.8-0.10.00.0
Bone: connectivity density0.50.75.22.30.20.2-0.60.7-0.20.50.00.0
Bone: cortical apparent density0.30.43.3-1.8-0.3-0.1-0.2-0.20.6-0.30.00.0
Bone: cortical area0.50.71.81.31.30.51.3-0.7-0.6-0.30.00.0
Bone: cortical porosity0.10.10.4-0.3-0.20.1-0.60.60.30.40.00.0
Bone: cortical porosity0.20.20.6-0.7-0.8-0.5-0.50.30.00.00.00.0
Bone: cortical thickness0.40.71.80.21.31.3-0.40.81.21.00.00.0
Bone: cortical thickness0.00.00.1-0.10.0-0.10.3-0.3-0.2-0.40.00.0
Bone: cortical tissue density0.30.53.4-1.9-0.4-0.2-0.3-0.20.6-0.30.00.0
Condit. Reinf. active minus inactive responses0.40.53.2-1.8-0.7-0.4-0.2-0.20.3-0.30.00.0
Condit. Reinf. active-inactive response ratio0.50.61.5-0.70.10.6-1.10.91.20.90.00.0
Condit. Reinf. active responses0.60.82.1-1.5-1.1-1.10.4-0.9-0.7-1.00.00.0
Condit. Reinf. inactive responses1.51.84.3-0.2-0.6-1.31.8-1.9-2.1-1.70.00.0
Incentive salience index mean0.30.41.9-1.4-0.3-0.40.5-0.7-0.3-0.60.00.0
Condit. Reinf. lever presses0.30.41.3-0.60.4-0.01.1-1.1-0.6-0.70.00.0
Condit. Reinf. active minus inactive responses1.52.05.31.00.3-0.72.3-2.0-2.1-1.50.00.0
Condit. Reinf. active-inactive response ratio1.82.14.50.4-0.6-1.42.1-2.1-2.1-1.80.00.0
Condit. Reinf. active responses1.52.16.01.61.2-0.02.5-1.9-2.0-1.20.00.0
Condit. Reinf. inactive responses0.60.73.01.21.71.20.6-0.0-0.00.40.00.0
Condit. Reinf. lever presses0.40.51.91.41.20.80.50.0-0.30.40.00.0
Condit. Reinf. lever reinforcers received1.92.67.01.91.1-0.22.6-2.1-2.3-1.40.00.0
Conditioned reinforcement - actives1.22.110.1-3.2-1.9-1.40.2-0.7-0.9-1.2-0.2-0.9
Conditioned reinforcement - inactives1.52.25.0-2.2-0.2-0.61.9-2.0-1.2-1.7-1.20.5
Conditioned locomotion0.81.06.5-2.5-1.2-0.80.0-0.3-0.4-0.70.1-0.5
Patch foraging indifference point 0 sec1.12.06.81.02.62.4-0.21.00.91.60.00.0
Patch foraging indifference point AUC0.30.51.60.1-0.8-0.2-1.30.90.90.50.00.0
Delay disc. indifference point, 0s delay2.52.811.93.42.72.00.60.30.50.9-0.00.5
Delay disc. indifference point, 16s delay1.61.76.8-2.6-1.3-0.7-1.70.81.40.50.8-0.3
Delay disc. indifference point, 2s delay0.70.82.2-0.01.51.4-0.10.51.00.90.8-0.2
Delay disc. indifference point, 24s delay0.91.03.2-1.8-0.9-0.2-1.20.71.00.40.9-0.9
Delay disc. indifference point, 4s delay0.10.10.20.40.1-0.00.1-0.20.4-0.20.2-0.1
Delay disc. indifference point, 8s delay1.31.54.3-0.22.12.0-0.50.91.21.41.0-0.1
Indifference point function ln k2.44.213.5-0.41.90.23.7-3.0-2.8-1.90.00.0
Indifference point function log k2.44.213.5-0.41.90.23.7-3.0-2.8-1.90.00.0
Patch foraging total patch changes 0 sec1.01.96.80.72.62.4-0.21.01.01.50.00.0
Patch foraging total patch changes 12 sec0.30.41.40.6-0.30.1-1.20.90.90.70.00.0
Patch foraging total patch changes 18 sec0.60.91.91.40.81.0-0.91.21.11.20.00.0
Patch foraging total patch changes 24 sec0.50.84.30.2-2.1-1.6-0.70.20.0-0.40.00.0
Patch foraging total patch changes 6 sec0.50.81.8-0.40.20.7-1.21.31.31.10.00.0
Patch foraging time to switch 0 sec2.85.820.8-2.9-4.6-2.6-3.21.81.70.10.00.0
Patch foraging water rate 0 sec0.92.06.82.02.61.61.7-0.7-0.80.20.00.0
Patch foraging water rate 12 sec1.73.613.81.23.72.22.8-1.7-1.3-0.20.00.0
Patch foraging water rate 18 sec1.11.66.90.22.61.71.8-0.9-0.90.10.00.0
Patch foraging water rate 24 sec0.71.02.61.01.40.61.6-1.0-1.3-0.40.00.0
Patch foraging water rate 6 sec2.94.210.60.1-0.0-1.43.2-3.2-3.0-2.50.00.0
Seeking ratio, delayed vs. immediate footshock3.34.013.33.53.72.81.00.3-0.01.3-0.00.9
Distance traveled before self-admin2.83.712.02.33.52.32.6-1.1-1.0-0.1-1.10.8
Distance traveled after self-admin5.16.219.84.04.53.70.50.90.92.00.40.3
Extensor digitorum longus weight0.00.10.40.30.2-0.10.6-0.5-0.5-0.40.00.0
Bone: elastic displacement0.80.92.4-0.11.51.5-0.70.91.01.30.00.0
Bone: elastic work0.70.94.40.82.11.50.6-0.10.00.50.00.0
Bone: endosteal estimation1.63.48.11.2-0.7-1.72.5-2.5-2.8-2.20.00.0
Bone: endosteal perimeter0.81.64.11.20.1-0.82.0-1.7-2.0-1.40.00.0
Epididymis fat weight0.41.25.6-1.4-2.4-1.7-0.50.20.2-0.60.00.0
Delta time in closed arm before/after self-admin0.30.31.91.40.30.2-0.00.30.50.30.20.2
Delta time in open arm before/after self-admin1.21.12.9-1.7-0.1-0.41.2-1.3-1.1-1.2-1.20.3
Diff in mean of infusions in LGA sessions0.81.04.6-0.32.11.80.5-0.00.20.60.50.0
Delay discount exponential model param0.91.02.00.1-1.4-1.40.7-0.8-1.4-1.1-1.10.5
Extinction: sum of active levers before priming0.30.32.61.60.20.1-0.20.30.10.2-0.30.2
Active lever presses in extinction session 62.12.18.0-2.1-2.8-2.1-0.80.00.3-0.80.4-1.0
Bone: final force0.81.33.90.70.4-0.52.0-1.8-1.5-1.40.00.0
Bone: final moment1.11.85.11.10.8-0.42.3-2.0-1.8-1.40.00.0
Food consumed during 24 hour testing period0.40.61.5-1.10.80.31.2-1.1-0.3-0.60.00.0
Glucose1.21.94.40.11.72.1-1.01.42.01.70.00.0
Heart weight0.60.95.2-2.3-0.1-0.41.0-1.1-0.2-0.90.00.0
Delay discount hyperbolic model param1.21.32.8-0.0-1.6-1.70.6-0.9-1.5-1.2-1.20.6
Intermittent access intake day 1-15 change0.71.56.3-2.5-1.1-1.10.7-1.2-0.9-1.3-0.5-0.3
Intermittent access intake escalation1.22.69.8-3.1-1.7-1.51.0-1.5-1.2-1.7-0.7-0.3
Intermittent access intake escalation 20.20.20.6-0.70.80.60.5-0.4-0.1-0.20.3-0.3
Intermitt. access day 1 inactive lever presses1.24.623.2-4.8-1.9-1.81.0-1.7-1.3-1.9-1.40.3
Intermitt. access day 15 inactive lever presses2.04.08.7-2.9-2.3-2.31.1-1.9-1.8-2.3-1.80.5
Intermitt. access escalation Index0.50.71.3-1.00.20.6-0.50.71.20.81.0-1.0
Intermittent access day 1 total infusions0.61.02.1-1.5-1.3-1.20.6-0.8-1.0-1.1-0.7-0.1
Intermittent access day 15 total infusions2.74.022.2-4.7-2.0-1.70.7-1.4-1.1-1.7-0.5-0.4
Intermittent access terminal intake (last 3 days)1.92.513.0-3.6-1.5-1.40.7-1.2-1.1-1.5-0.5-0.2
Intermittent access total infusions2.73.211.7-3.4-1.9-1.80.9-1.5-1.6-1.8-1.1-0.0
Intermittent access day 1 locomotion1.41.85.5-2.3-1.1-1.31.0-1.3-1.2-1.4-1.00.8
Intermittent access day 15 total locomotion0.91.77.0-2.61.00.61.7-1.4-1.0-0.9-0.50.4
Intermittent access total locomotion3.03.59.0-3.0-1.1-1.51.9-2.2-1.9-2.1-1.50.8
Intermittent access standard deviation0.51.14.7-2.20.81.1-0.40.50.70.61.0-0.9
Left kidney weight2.09.522.8-1.80.0-1.94.7-4.8-4.3-3.80.00.0
Right kidney weight2.19.421.6-2.6-0.8-2.44.3-4.6-3.9-3.90.00.0
Cocaine induced anxiety0.91.31.9-0.8-0.6-1.01.1-1.4-1.1-1.2-1.41.3
Post-drug Anxiety1.61.73.7-1.1-1.8-1.90.1-1.1-1.1-1.3-1.41.2
Baseline Anxiety0.40.51.30.90.20.3-1.10.90.60.90.50.2
Tail length1.35.011.2-1.90.2-1.13.3-3.3-3.3-2.60.00.0
Length with tail1.66.813.7-1.8-1.4-2.53.5-3.6-3.7-3.30.00.0
Length without tail1.75.612.2-2.1-3.4-3.51.7-2.4-2.2-2.90.00.0
Times rat made contact with spout0.20.30.80.90.50.5-0.40.60.40.60.00.0
Lifetime Intake1.92.47.9-2.8-1.9-1.70.7-1.2-1.3-1.6-0.8-0.3
Liver weight, left0.61.02.3-1.2-0.3-0.81.4-1.5-1.1-1.30.00.0
Liver weight, right0.10.31.1-0.01.10.90.40.10.30.40.00.0
Locomotor activity0.20.30.60.40.20.5-0.80.80.80.70.00.0
Locomotor testing distance0.10.20.8-0.1-0.9-0.6-0.50.20.0-0.10.00.0
Locomotor testing rearing0.10.21.21.1-0.0-0.20.5-0.3-0.6-0.20.00.0
Locomotion in novel chamber0.60.81.50.70.80.7-0.91.00.91.20.60.9
Locomotion in novel chamber post-restriction0.71.11.91.31.01.1-0.91.11.01.40.90.1
Fecal boli incidents, locomotor time 10.10.20.80.40.90.60.6-0.3-0.2-0.00.00.2
Change in fecal boli incidents, locomotor task2.12.13.30.31.21.5-1.51.61.81.81.8-0.7
Time >=10cm from walls, locomotor time 10.40.41.9-1.4-0.8-0.5-0.70.30.30.00.2-0.1
Bouts of movement, locomotor time 12.02.39.71.93.12.31.1-0.30.10.70.10.8
Total resting periods, locomotor time 11.31.56.01.32.41.80.50.10.50.90.41.0
Rest time, locomotor task time 10.50.61.20.8-0.3-0.80.9-1.0-0.5-0.8-0.51.1
Distance moved, locomotor task time 10.40.61.1-0.30.40.8-1.01.00.90.90.5-1.0
Vertical activity count, locomotor time 11.74.110.11.23.03.2-1.01.81.62.31.3-1.4
Time >=10cm from walls, locomotor time 20.40.62.0-0.4-1.2-0.7-1.40.80.70.40.6-0.4
Bouts of movement, locomotor time 20.20.32.00.80.60.1-0.00.10.00.4-0.11.4
Total resting periods, locomotor time 20.30.52.41.30.70.20.10.00.00.4-0.11.6
Rest time, locomotor task time 21.11.35.72.41.81.10.40.10.00.70.01.1
Distance moved, locomotor task time 20.10.21.20.2-0.30.0-0.30.30.20.0-0.0-1.1
Vertical activity count, locomotor time 20.50.71.51.11.11.2-0.20.60.40.60.4-1.2
Light reinforcement 10.51.13.91.92.01.40.60.1-0.20.60.00.0
Light reinforcement 20.20.41.0-0.2-0.00.4-0.91.00.80.80.00.0
Bone: marrow area1.63.48.21.3-0.7-1.72.5-2.5-2.9-2.20.00.0
Bone: maximum diameter0.30.51.41.00.90.21.2-0.8-0.9-0.50.00.0
Bone: maximum force0.81.54.71.00.8-0.22.2-1.8-1.5-1.30.00.0
Bone: maximum moment1.12.05.71.41.1-0.12.4-1.9-1.8-1.30.00.0
Mean time between licks in bursts0.30.82.10.11.31.4-0.40.91.21.10.00.0
Mean num. licks in bursts0.20.42.41.50.60.5-0.20.40.00.40.00.0
Cd content in liver0.70.81.9-0.3-0.4-0.91.3-1.4-1.1-1.20.00.0
Co content in liver0.50.61.5-1.1-0.3-0.60.8-1.2-0.5-1.10.00.0
Cu content in liver2.02.44.9-1.2-2.0-2.21.2-1.7-1.7-1.90.00.0
Fe content in liver1.11.33.2-1.8-1.7-1.60.3-0.8-0.8-1.20.00.0
K content in liver0.10.10.40.1-0.3-0.40.3-0.3-0.6-0.30.00.0
Mg content in liver0.40.41.5-0.7-1.2-0.9-0.4-0.0-0.4-0.30.00.0
Mn content in liver0.20.30.9-0.9-0.9-0.7-0.30.1-0.3-0.20.00.0
Na content in liver0.40.41.50.1-0.6-0.0-1.21.00.40.70.00.0
Rb content in liver2.52.96.2-0.7-1.6-2.11.9-2.2-2.5-2.10.00.0
Se content in liver0.81.02.6-0.30.00.7-1.61.61.21.30.00.0
Sr content in liver6.85.912.01.83.13.5-2.02.72.73.10.00.0
Zn content in liver1.21.35.1-1.8-2.3-1.5-1.00.30.3-0.40.00.0
Bone: minimum diameter1.42.66.42.41.0-0.32.5-1.9-2.2-1.30.00.0
Time in familiar zone, hab. session 12.32.25.81.92.20.92.4-1.6-1.3-0.70.00.0
Time in novel zone, hab. session 11.91.96.1-1.8-2.5-1.4-1.91.10.80.10.00.0
Total zone transitions, hab. session 11.01.53.81.90.8-0.11.7-1.4-1.8-0.90.00.0
Total locomotion distance, hab. session 10.91.34.32.12.11.30.9-0.3-0.50.40.00.0
Locomotion velocity, hab. session 10.60.82.61.51.61.00.7-0.3-0.60.20.00.0
Time in familiar zone, hab. session 21.31.42.5-0.8-1.3-1.61.1-1.4-1.4-1.60.00.0
Time in novel zone, hab. session 20.40.41.20.1-0.20.3-1.11.00.80.80.00.0
Total zone transitions, hab. session 21.72.24.82.22.00.72.1-1.5-1.9-0.60.00.0
Total locomotion distance, hab. session 21.52.07.22.22.72.10.30.40.01.10.00.0
Locomotion velocity, hab. session 21.82.48.82.33.02.40.30.50.11.30.00.0
Novel to familiar place preference ratio0.40.51.70.91.31.00.30.10.20.50.00.0
Novelty place preference0.20.31.00.71.00.70.6-0.3-0.10.20.00.0
Time in novel zone, NPP test0.20.20.60.60.80.50.6-0.3-0.20.00.00.0
Total zone transitions, NPP test0.30.51.91.11.40.90.7-0.3-0.30.20.00.0
Total locomotion distance, NPP test0.81.14.41.12.11.70.20.40.30.90.00.0
Locomotion velocity, NPP test0.91.35.61.42.41.80.40.30.10.90.00.0
Intraocular pressure0.10.20.6-0.1-0.8-0.7-0.3-0.2-0.2-0.40.00.0
Delta distance traveled before/after self-admin1.71.83.30.51.21.6-1.51.71.41.81.3-0.7
Delta ambulatory time before/after self-admin1.51.82.90.01.41.7-1.31.51.61.71.4-0.7
Parametrial fat weight1.43.27.2-0.31.42.2-2.02.42.72.40.00.0
Pavlov. Cond. lever latency0.00.00.10.0-0.3-0.3-0.10.0-0.0-0.10.00.0
Pavlov. Cond. magazine entry latency0.60.71.70.60.30.7-1.31.31.11.10.00.0
Pavlov. Cond. change in total contacts0.20.20.40.40.50.6-0.30.40.40.50.00.0
Pavlov. Cond. index score0.30.30.60.50.60.8-0.60.70.60.70.00.0
Pavlov. Cond. latency score0.30.30.70.30.70.8-0.60.70.70.70.00.0
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.0-0.00.0-0.1-0.1-0.00.00.0
Pavlov. Cond. magazine entry number0.40.51.4-1.2-0.4-0.60.8-0.9-0.5-0.80.00.0
Pavlov. Cond. intertrial magazine entries0.20.31.00.61.00.50.8-0.5-0.5-0.00.00.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.30.50.7-0.60.70.70.70.00.0
Pavlov. Cond. response bias0.10.10.40.6-0.3-0.0-0.60.50.10.30.00.0
Pavlov. Cond. lever latency2.02.86.9-2.3-2.6-2.50.6-1.4-0.8-1.90.00.0
Pavlov. Cond. magazine entry latency1.21.52.80.91.21.6-1.21.61.21.70.00.0
Pavlov. Cond. change in total contacts1.01.65.62.42.21.60.60.2-0.20.80.00.0
Pavlov. Cond. index score1.11.53.61.91.91.7-0.41.10.51.40.00.0
Pavlov. Cond. latency score1.41.94.01.52.02.0-0.81.50.91.70.00.0
Pavlov. Cond. lever contacts1.72.36.12.32.52.2-0.31.10.61.60.00.0
Pavlov. Cond. magazine entry number0.70.91.6-1.1-0.9-1.10.9-1.3-0.8-1.30.00.0
Pavlov. Cond. intertrial magazine entries2.13.26.6-0.1-0.9-1.92.5-2.6-2.4-2.40.00.0
Pavlov. Cond. lever-magazine prob. diff.1.11.53.31.81.81.7-0.41.10.51.40.00.0
Pavlov. Cond. response bias1.11.55.82.42.01.60.30.5-0.01.00.00.0
Time in closed arm before self-admin0.91.27.0-2.6-0.1-0.21.0-1.0-0.9-0.9-0.2-0.2
Time in closed arm after self-admin0.20.20.8-0.9-0.5-0.60.2-0.4-0.4-0.4-0.30.5
Time in open arm before self-admin2.32.510.83.30.91.0-1.31.61.41.61.1-0.2
Time in open arm after self-admin0.30.42.21.50.50.5-0.40.50.40.5-0.1-0.0
Bone: periosteal estimation1.02.25.12.00.4-0.72.2-1.9-2.2-1.50.00.0
Bone: periosteal perimeter1.11.84.62.10.0-0.91.8-1.5-1.9-1.40.00.0
Bone: post-yield work1.72.44.70.2-1.7-2.21.6-1.9-2.0-2.10.00.0
Progressive ratio test 1 active lever presses0.40.51.10.50.3-0.01.0-0.9-0.7-0.8-0.90.1
Progressive ratio test 1 breakpoint0.40.41.00.50.40.11.0-0.9-0.7-0.7-0.90.2
Progressive ratio test 1 inactive lever presses2.33.45.3-2.1-1.5-1.81.7-2.1-2.0-2.3-1.90.4
Progressive ratio test 2 active lever presses2.02.411.8-3.4-1.9-1.50.3-0.9-0.8-1.3-0.1-0.8
Progressive ratio test 2 breakpoint2.32.712.2-3.5-2.1-1.60.3-1.0-0.9-1.5-0.2-0.7
Progressive ratio test 2 inactive lever presses2.54.17.3-2.7-1.5-1.71.9-2.4-2.2-2.5-2.00.5
Incentive Sensitization - Responses3.24.521.0-4.6-2.6-2.20.7-1.5-1.1-2.0-0.4-0.4
Incentive Sensitization - Breakpoint3.24.119.8-4.4-2.6-2.10.5-1.3-1.0-1.8-0.2-0.6
Sum of active levers in priming session hrs 5-60.70.72.5-0.81.61.40.20.20.50.70.50.2
Progressive ratio0.60.93.11.81.61.20.00.40.30.60.30.1
Food seeking constrained by brief footshock13.716.860.46.47.86.11.80.61.02.60.80.6
Seeking ratio, punishment vs. effort0.91.34.31.32.11.41.4-0.6-0.30.1-0.40.6
Retroperitoneal fat weight2.08.521.9-1.8-1.21.1-4.44.44.73.20.00.0
Reaction time number correct0.81.54.82.21.81.6-0.30.90.21.30.00.0
Reaction time mean minus median0.10.31.3-0.5-1.2-0.9-0.1-0.1-0.2-0.40.00.0
Reaction time mean minus median AUC0.20.52.4-0.0-1.6-1.3-0.2-0.0-0.3-0.50.00.0
Reaction time num false alarms0.10.20.7-0.90.60.6-0.10.1-0.00.30.00.0
Reaction time num false alarms AUC0.30.51.60.01.31.2-0.40.50.20.80.00.0
Reaction time trials correct on left0.81.54.82.21.81.6-0.30.90.21.30.00.0
Reaction time trials on left0.81.44.52.11.81.6-0.20.90.21.30.00.0
Reaction time mean1.82.87.3-2.7-2.5-2.30.4-1.3-1.3-1.70.00.0
Reaction time mean AUC1.52.47.9-2.8-2.5-2.1-0.0-0.8-0.8-1.40.00.0
Median of all reaction times2.12.98.6-2.9-2.5-2.30.3-1.3-1.3-1.70.00.0
Reaction time omissions0.10.10.5-0.20.70.60.00.00.00.30.00.0
Reaction time false alarm rate0.10.21.3-1.10.30.4-0.2-0.00.20.10.00.0
Reaction time premature initiation rate0.10.10.4-0.60.20.3-0.30.10.40.20.00.0
Reaction time premature initiations0.30.51.20.51.01.1-0.50.70.60.90.00.0
Std. dev. reaction times0.71.24.0-2.0-1.6-1.40.4-0.8-0.8-1.10.00.0
Reaction time trials completed0.81.44.52.11.81.6-0.20.90.21.30.00.0
Reaction time trials AUC0.71.44.12.01.71.6-0.31.00.21.30.00.0
Run reversals in cocaine runway, females1.11.18.8-3.0-0.5-0.6-0.2-0.3-0.1-0.3-0.20.8
Run reversals in cocaine runway, males0.40.41.8-0.0-1.3-1.2-0.0-0.3-0.3-0.7-0.2-0.1
Latency to leave start box in cocaine runway0.60.74.0-2.0-0.2-0.30.7-0.90.1-0.70.20.0
Latency to leave start box in cocaine runway, F0.50.53.1-1.80.20.30.2-0.30.7-0.10.8-0.5
Latency to leave start box in cocaine runway, M1.61.52.6-1.0-1.3-1.50.9-1.5-1.1-1.6-1.00.7
Std. dev. time between licks in bursts0.50.73.20.71.81.30.50.00.10.50.00.0
Total sessions with >9 infusions1.31.62.7-0.0-1.3-1.41.1-1.3-1.6-1.6-1.50.2
Short access day 1 total inactive lever presses2.02.66.1-2.2-2.5-2.20.7-1.3-1.0-1.8-1.0-0.1
Short access day 10 total inactive lever presses0.10.31.6-1.30.0-0.10.5-0.6-0.2-0.4-0.20.7
Short access day 1 total infusions0.30.41.30.0-1.1-1.00.2-0.3-0.4-0.7-0.3-0.4
Short access day 10 total infusions0.30.31.4-0.6-0.9-0.5-0.1-0.0-0.4-0.40.0-1.2
Short access total infusions0.20.21.0-0.0-0.8-0.4-0.30.1-0.1-0.20.2-1.0
Short access day 1 locomotion2.12.68.4-1.2-2.9-2.60.3-1.0-1.2-1.8-1.0-0.2
Short access day 10 total locomotion0.61.11.7-0.61.00.31.3-1.3-1.2-0.8-1.31.3
Short access total locomotion0.50.61.40.81.20.81.0-0.6-0.7-0.3-0.70.3
One hour access (0.3 mA shock)5.26.019.0-4.4-1.9-2.21.9-2.5-2.3-2.6-1.91.0
Compulsive drug intake2.12.53.6-1.9-1.3-1.61.5-1.8-1.5-1.9-1.70.9
One hour access (shock baseline)1.62.411.9-3.5-2.1-1.6-0.1-0.6-0.7-1.2-0.1-0.6
Social response proportion2.52.912.8-3.6-2.1-1.90.7-1.3-0.4-1.70.00.0
Social responses3.03.96.3-2.4-2.1-2.41.8-2.4-2.0-2.50.00.0
Social time1.72.47.50.92.00.72.7-2.1-1.7-1.10.00.0
Soleus weight0.10.20.90.41.00.8-0.00.30.50.40.00.0
Bone: stiffness1.01.64.4-0.2-0.1-0.92.1-2.0-1.6-1.70.00.0
Tibialis anterior weight0.93.05.81.41.62.1-1.62.42.12.30.00.0
Time to tail flick, vehicle, before self-admin0.40.41.7-0.11.31.00.6-0.30.00.10.1-0.1
Time to tail flick, vehicle, after self-admin1.31.74.1-1.9-2.0-2.0-0.0-0.9-0.5-1.2-0.40.8
Time to tail flick, test, before self-admin3.73.813.23.13.62.81.00.20.61.20.00.8
Time to tail flick, test, after self-admin0.20.20.60.00.00.2-0.70.50.80.50.20.0
Delta time to tail flick, vehicle, before/after SA1.21.24.7-1.0-2.2-1.9-0.4-0.4-0.1-0.8-0.20.4
Delta time to tail flick, test, before/after SA1.92.06.7-2.3-2.6-2.0-0.8-0.2-0.3-0.8-0.2-0.2
Tibia length1.44.010.11.00.5-1.03.2-2.9-3.2-2.20.00.0
Ambulatory time before self-admin2.02.97.32.72.41.42.2-1.1-1.3-0.4-1.41.1
Ambulatory time after self-admin3.74.416.63.04.13.21.10.30.51.3-0.00.6
Bone: tissue strength1.91.98.90.83.02.40.60.10.60.90.00.0
Total heroin consumption0.10.20.40.30.60.70.00.30.30.40.4-0.4
Bone: trabecular number0.71.17.52.70.60.5-0.50.80.30.70.00.0
Bone: trabecular spacing0.00.00.1-0.10.30.30.1-0.00.10.10.00.0
Bone: trabecular thickness0.10.10.5-0.1-0.7-0.6-0.20.10.2-0.20.00.0
Bone: trabecular tissue density1.21.87.6-2.8-2.0-1.0-1.40.71.20.10.00.0
Water consumed over 24 hours0.50.71.70.81.30.61.3-0.9-0.8-0.40.00.0
Number of responses in last shaping day2.32.57.9-2.8-2.7-2.1-0.6-0.5-0.5-1.2-0.2-0.9