Hub : Genes

Zfp329

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Zfp329 0.3 0.14 5.6e-03 0 0.03 0.02 -0 1.9e-01 7.1e-03 3.3e-02 7.5e-01
2 PL mRNA stability Zfp329 0.19 0.09 2.2e-05 0.01 0.03 0.03 0.02 5.1e-02 5.1e-04 8.9e-04 2.8e-03
3 NAcc mRNA stability Zfp329 0.26 0.1 9.0e-15 0.07 0.1 0.1 0.07 7.5e-11 4.2e-15 3.2e-14 2.0e-11
4 Eye intron excision ratio chr1_82483925_82493934 0.42 0.28 7.4e-03 0.08 0.03 -0.01 0.04 2.3e-02 1.2e-01 6.1e-01 9.8e-02
5 Adipose gene expression Zfp329 0.06 0.04 5.5e-05 0.03 0.03 0.02 0.02 1.7e-04 7.3e-04 4.3e-03 1.6e-03
6 Liver mRNA stability Zfp329 0.16 0.09 1.8e-06 0.04 0.03 0.02 0.04 3.7e-05 2.6e-04 1.6e-03 3.0e-05
7 Adipose mRNA stability Zfp329 0.15 0.07 3.3e-09 0.06 0.06 0.06 0.06 4.0e-07 3.0e-07 4.7e-07 6.5e-07
8 Brain intron excision ratio chr1_82483925_82493934 0.02 0.02 5.7e-03 0.01 0 0 0.02 7.8e-02 1.5e-01 2.6e-01 2.6e-03
9 Brain intron excision ratio chr1_82413569_82418598 0.07 0.07 6.7e-03 0.01 0.03 0.03 0.03 4.1e-02 2.0e-03 7.6e-04 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.32.91.70.2-0.0-0.2-0.0-0.2-0.00.00.0
Area under the delay curve0.81.22.30.11.51.50.8-0.91.51.21.10.4
BMI with tail0.31.13.4-0.10.20.81.4-1.61.81.30.00.0
BMI without tail0.10.43.0-1.70.20.3-0.0-0.00.40.10.00.0
Body weight0.52.04.8-1.7-0.3-1.0-2.21.9-1.7-1.60.00.0
Weight adjusted by age0.20.61.41.20.90.5-1.10.7-0.8-0.4-0.7-0.2
Bone surface1.42.76.01.1-0.8-1.7-2.12.2-2.4-2.10.00.0
Bone volume1.12.34.21.0-1.0-1.8-1.92.0-2.0-2.00.00.0
Breakpoint value in progressive ratio session0.91.67.7-2.80.81.00.9-0.71.01.01.20.2
Number of licking bursts0.10.21.2-1.1-0.4-0.30.10.10.2-0.20.00.0
Context. condit. distance diff. score0.30.41.71.31.00.8-0.1-0.3-0.30.50.00.0
Locomotion velocity, session 10.60.62.00.91.40.8-1.00.7-0.8-0.10.00.0
Locomotion distance, session 11.51.95.70.81.60.4-2.42.0-1.7-1.00.00.0
Locomotion velocity, session 20.20.21.31.10.60.4-0.30.1-0.40.10.00.0
Locomotion distance, session 20.81.22.70.3-0.1-0.8-1.61.6-1.6-1.40.00.0
Locomotion velocity, session 30.10.10.20.3-0.4-0.50.10.0-0.4-0.20.00.0
Locomotion distance, session 31.11.28.62.90.80.2-0.60.2-1.2-0.10.00.0
Stereotopy head waving bouts, day 30.50.54.6-2.1-0.10.10.00.10.50.00.00.0
Stereotopy head waving duration, day 30.60.76.4-2.5-0.10.1-0.10.20.50.00.00.0
Locomotion velocity, session 70.10.10.4-0.20.1-0.2-0.60.6-0.6-0.40.00.0
Locomotion distance, session 70.00.00.10.20.40.2-0.40.3-0.2-0.10.00.0
Stereotopy head waving bouts, day 70.30.40.9-0.0-0.9-0.9-0.30.5-0.9-0.60.00.0
Stereotopy head waving duration, day 70.20.20.4-0.3-0.5-0.6-0.40.5-0.6-0.50.00.0
Locomotion velocity, session 80.10.20.70.40.90.5-0.50.3-0.30.00.00.0
Locomotion distance, session 80.40.52.21.51.00.4-0.70.4-1.0-0.10.00.0
Degree of sensitization distance0.50.54.1-2.00.20.3-0.10.20.6-0.00.00.0
Degree of sensitization stereotypy0.50.53.11.8-0.6-0.70.0-0.0-1.0-0.20.00.0
Conditioned locomotion0.20.31.40.21.20.9-0.30.0-0.00.40.00.0
Cocaine response after cond. corrected1.31.96.1-2.3-2.5-1.51.5-0.70.6-0.20.00.0
Cocaine response after cond. not corrected0.81.13.2-1.7-1.8-1.50.00.6-0.5-1.00.00.0
Cocaine response before conditioning2.53.08.91.61.50.1-3.02.4-2.2-1.50.00.0
Saline control response0.60.84.72.20.90.3-0.70.4-0.8-0.10.00.0
Bone: connectivity density0.40.75.22.30.20.20.6-0.7-0.20.50.00.0
Bone: cortical apparent density0.30.43.3-1.8-0.3-0.10.20.20.6-0.30.00.0
Bone: cortical area0.40.71.81.31.30.5-1.30.7-0.6-0.30.00.0
Bone: cortical porosity0.10.10.4-0.3-0.20.10.6-0.60.30.40.00.0
Bone: cortical porosity0.20.20.6-0.7-0.8-0.50.5-0.30.00.00.00.0
Bone: cortical thickness0.40.71.80.21.31.30.4-0.81.21.00.00.0
Bone: cortical thickness0.00.00.1-0.10.0-0.1-0.30.3-0.2-0.40.00.0
Bone: cortical tissue density0.30.53.4-1.9-0.4-0.20.30.20.6-0.30.00.0
Condit. Reinf. active minus inactive responses0.40.53.2-1.8-0.7-0.40.20.20.3-0.30.00.0
Condit. Reinf. active-inactive response ratio0.50.61.5-0.70.10.61.1-0.91.20.90.00.0
Condit. Reinf. active responses0.60.82.1-1.5-1.1-1.1-0.40.9-0.7-1.00.00.0
Condit. Reinf. inactive responses1.41.84.3-0.2-0.6-1.3-1.81.9-2.1-1.70.00.0
Incentive salience index mean0.30.41.9-1.4-0.3-0.4-0.50.7-0.3-0.60.00.0
Condit. Reinf. lever presses0.30.41.3-0.60.4-0.0-1.11.1-0.6-0.70.00.0
Condit. Reinf. active minus inactive responses1.32.05.31.00.3-0.7-2.32.0-2.1-1.50.00.0
Condit. Reinf. active-inactive response ratio1.32.14.50.4-0.6-1.4-2.12.1-2.1-1.80.00.0
Condit. Reinf. active responses1.42.16.01.61.2-0.0-2.51.9-2.0-1.20.00.0
Condit. Reinf. inactive responses0.50.73.01.21.71.2-0.60.0-0.00.40.00.0
Condit. Reinf. lever presses0.30.51.91.41.20.8-0.5-0.0-0.30.40.00.0
Condit. Reinf. lever reinforcers received1.92.67.01.91.1-0.2-2.62.1-2.3-1.40.00.0
Conditioned reinforcement - actives0.52.110.1-3.2-1.9-1.4-0.20.7-0.9-1.2-0.20.9
Conditioned reinforcement - inactives0.82.25.0-2.2-0.2-0.6-1.92.0-1.2-1.7-1.2-0.5
Conditioned locomotion0.71.06.5-2.5-1.2-0.8-0.00.3-0.4-0.70.10.5
Patch foraging indifference point 0 sec0.72.06.81.02.62.40.2-1.00.91.60.00.0
Patch foraging indifference point AUC0.20.51.60.1-0.8-0.21.3-0.90.90.50.00.0
Delay disc. indifference point, 0s delay2.52.811.93.42.72.0-0.6-0.30.50.90.0-0.5
Delay disc. indifference point, 16s delay1.21.76.8-2.6-1.3-0.71.7-0.81.40.50.80.3
Delay disc. indifference point, 2s delay0.70.82.2-0.01.51.40.1-0.51.00.90.80.2
Delay disc. indifference point, 24s delay0.61.03.2-1.8-0.9-0.21.2-0.71.00.40.90.9
Delay disc. indifference point, 4s delay0.10.10.20.40.1-0.0-0.10.20.4-0.20.20.1
Delay disc. indifference point, 8s delay0.91.54.3-0.22.12.00.5-0.91.21.41.00.1
Indifference point function ln k1.44.213.5-0.41.90.2-3.73.0-2.8-1.90.00.0
Indifference point function log k1.44.213.5-0.41.90.2-3.73.0-2.8-1.90.00.0
Patch foraging total patch changes 0 sec0.71.96.80.72.62.40.2-1.01.01.50.00.0
Patch foraging total patch changes 12 sec0.30.41.40.6-0.30.11.2-0.90.90.70.00.0
Patch foraging total patch changes 18 sec0.40.91.91.40.81.00.9-1.21.11.20.00.0
Patch foraging total patch changes 24 sec0.20.84.30.2-2.1-1.60.7-0.20.0-0.40.00.0
Patch foraging total patch changes 6 sec0.50.81.8-0.40.20.71.2-1.31.31.10.00.0
Patch foraging time to switch 0 sec1.55.820.8-2.9-4.6-2.63.2-1.81.70.10.00.0
Patch foraging water rate 0 sec0.52.06.82.02.61.6-1.70.7-0.80.20.00.0
Patch foraging water rate 12 sec0.93.613.81.23.72.2-2.81.7-1.3-0.20.00.0
Patch foraging water rate 18 sec0.71.66.90.22.61.7-1.80.9-0.90.10.00.0
Patch foraging water rate 24 sec0.71.02.61.01.40.6-1.61.0-1.3-0.40.00.0
Patch foraging water rate 6 sec2.94.210.60.1-0.0-1.4-3.23.2-3.0-2.50.00.0
Seeking ratio, delayed vs. immediate footshock2.84.013.33.53.72.8-1.0-0.3-0.01.3-0.0-0.9
Distance traveled before self-admin1.73.712.02.33.52.3-2.61.1-1.0-0.1-1.1-0.8
Distance traveled after self-admin3.56.219.84.04.53.7-0.5-0.90.92.00.4-0.3
Extensor digitorum longus weight0.00.10.40.30.2-0.1-0.60.5-0.5-0.40.00.0
Bone: elastic displacement0.70.92.4-0.11.51.50.7-0.91.01.30.00.0
Bone: elastic work0.70.94.40.82.11.5-0.60.10.00.50.00.0
Bone: endosteal estimation1.43.48.11.2-0.7-1.7-2.52.5-2.8-2.20.00.0
Bone: endosteal perimeter0.71.64.11.20.1-0.8-2.01.7-2.0-1.40.00.0
Epididymis fat weight0.21.25.6-1.4-2.4-1.70.5-0.20.2-0.60.00.0
Delta time in closed arm before/after self-admin0.30.31.91.40.30.20.0-0.30.50.30.2-0.2
Delta time in open arm before/after self-admin1.01.12.9-1.7-0.1-0.4-1.21.3-1.1-1.2-1.2-0.3
Diff in mean of infusions in LGA sessions0.51.04.6-0.32.11.8-0.50.00.20.60.5-0.0
Delay discount exponential model param0.81.02.00.1-1.4-1.4-0.70.8-1.4-1.1-1.1-0.5
Extinction: sum of active levers before priming0.20.32.61.60.20.10.2-0.30.10.2-0.3-0.2
Active lever presses in extinction session 62.12.18.0-2.1-2.8-2.10.8-0.00.3-0.80.41.0
Bone: final force0.81.33.90.70.4-0.5-2.01.8-1.5-1.40.00.0
Bone: final moment1.11.85.11.10.8-0.4-2.32.0-1.8-1.40.00.0
Food consumed during 24 hour testing period0.30.61.5-1.10.80.3-1.21.1-0.3-0.60.00.0
Glucose1.21.94.40.11.72.11.0-1.42.01.70.00.0
Heart weight0.60.95.2-2.3-0.1-0.4-1.01.1-0.2-0.90.00.0
Delay discount hyperbolic model param1.01.32.8-0.0-1.6-1.7-0.60.9-1.5-1.2-1.2-0.6
Intermittent access intake day 1-15 change0.31.56.3-2.5-1.1-1.1-0.71.2-0.9-1.3-0.50.3
Intermittent access intake escalation0.52.69.8-3.1-1.7-1.5-1.01.5-1.2-1.7-0.70.3
Intermittent access intake escalation 20.10.20.6-0.70.80.6-0.50.4-0.1-0.20.30.3
Intermitt. access day 1 inactive lever presses0.44.623.2-4.8-1.9-1.8-1.01.7-1.3-1.9-1.4-0.3
Intermitt. access day 15 inactive lever presses0.74.08.7-2.9-2.3-2.3-1.11.9-1.8-2.3-1.8-0.5
Intermitt. access escalation Index0.20.71.3-1.00.20.60.5-0.71.20.81.01.0
Intermittent access day 1 total infusions0.31.02.1-1.5-1.3-1.2-0.60.8-1.0-1.1-0.70.1
Intermittent access day 15 total infusions1.64.022.2-4.7-2.0-1.7-0.71.4-1.1-1.7-0.50.4
Intermittent access terminal intake (last 3 days)1.52.513.0-3.6-1.5-1.4-0.71.2-1.1-1.5-0.50.2
Intermittent access total infusions2.73.211.7-3.4-1.9-1.8-0.91.5-1.6-1.8-1.10.0
Intermittent access day 1 locomotion1.01.85.5-2.3-1.1-1.3-1.01.3-1.2-1.4-1.0-0.8
Intermittent access day 15 total locomotion0.41.77.0-2.61.00.6-1.71.4-1.0-0.9-0.5-0.4
Intermittent access total locomotion3.03.59.0-3.0-1.1-1.5-1.92.2-1.9-2.1-1.5-0.8
Intermittent access standard deviation0.21.14.7-2.20.81.10.4-0.50.70.61.00.9
Left kidney weight1.29.522.8-1.80.0-1.9-4.74.8-4.3-3.80.00.0
Right kidney weight1.39.421.6-2.6-0.8-2.4-4.34.6-3.9-3.90.00.0
Cocaine induced anxiety0.51.31.9-0.8-0.6-1.0-1.11.4-1.1-1.2-1.4-1.3
Post-drug Anxiety1.51.73.7-1.1-1.8-1.9-0.11.1-1.1-1.3-1.4-1.2
Baseline Anxiety0.30.51.30.90.20.31.1-0.90.60.90.5-0.2
Tail length0.95.011.2-1.90.2-1.1-3.33.3-3.3-2.60.00.0
Length with tail1.56.813.7-1.8-1.4-2.5-3.53.6-3.7-3.30.00.0
Length without tail1.15.612.2-2.1-3.4-3.5-1.72.4-2.2-2.90.00.0
Times rat made contact with spout0.20.30.80.90.50.50.4-0.60.40.60.00.0
Lifetime Intake1.92.47.9-2.8-1.9-1.7-0.71.2-1.3-1.6-0.80.3
Liver weight, left0.61.02.3-1.2-0.3-0.8-1.41.5-1.1-1.30.00.0
Liver weight, right0.10.31.1-0.01.10.9-0.4-0.10.30.40.00.0
Locomotor activity0.20.30.60.40.20.50.8-0.80.80.70.00.0
Locomotor testing distance0.10.20.8-0.1-0.9-0.60.5-0.20.0-0.10.00.0
Locomotor testing rearing0.10.21.21.1-0.0-0.2-0.50.3-0.6-0.20.00.0
Locomotion in novel chamber0.60.81.50.70.80.70.9-1.00.91.20.6-0.9
Locomotion in novel chamber post-restriction0.41.11.91.31.01.10.9-1.11.01.40.9-0.1
Fecal boli incidents, locomotor time 10.10.20.80.40.90.6-0.60.3-0.2-0.00.0-0.2
Change in fecal boli incidents, locomotor task2.02.13.30.31.21.51.5-1.61.81.81.80.7
Time >=10cm from walls, locomotor time 10.30.41.9-1.4-0.8-0.50.7-0.30.30.00.20.1
Bouts of movement, locomotor time 11.82.39.71.93.12.3-1.10.30.10.70.1-0.8
Total resting periods, locomotor time 11.31.56.01.32.41.8-0.5-0.10.50.90.4-1.0
Rest time, locomotor task time 10.40.61.20.8-0.3-0.8-0.91.0-0.5-0.8-0.5-1.1
Distance moved, locomotor task time 10.20.61.1-0.30.40.81.0-1.00.90.90.51.0
Vertical activity count, locomotor time 10.64.110.11.23.03.21.0-1.81.62.31.31.4
Time >=10cm from walls, locomotor time 20.20.62.0-0.4-1.2-0.71.4-0.80.70.40.60.4
Bouts of movement, locomotor time 20.10.32.00.80.60.10.0-0.10.00.4-0.1-1.4
Total resting periods, locomotor time 20.10.52.41.30.70.2-0.1-0.00.00.4-0.1-1.6
Rest time, locomotor task time 20.81.35.72.41.81.1-0.4-0.10.00.70.0-1.1
Distance moved, locomotor task time 20.10.21.20.2-0.30.00.3-0.30.20.0-0.01.1
Vertical activity count, locomotor time 20.30.71.51.11.11.20.2-0.60.40.60.41.2
Light reinforcement 10.31.13.91.92.01.4-0.6-0.1-0.20.60.00.0
Light reinforcement 20.20.41.0-0.2-0.00.40.9-1.00.80.80.00.0
Bone: marrow area1.43.48.21.3-0.7-1.7-2.52.5-2.9-2.20.00.0
Bone: maximum diameter0.30.51.41.00.90.2-1.20.8-0.9-0.50.00.0
Bone: maximum force0.81.54.71.00.8-0.2-2.21.8-1.5-1.30.00.0
Bone: maximum moment1.02.05.71.41.1-0.1-2.41.9-1.8-1.30.00.0
Mean time between licks in bursts0.10.82.10.11.31.40.4-0.91.21.10.00.0
Mean num. licks in bursts0.10.42.41.50.60.50.2-0.40.00.40.00.0
Cd content in liver0.70.81.9-0.3-0.4-0.9-1.31.4-1.1-1.20.00.0
Co content in liver0.50.61.5-1.1-0.3-0.6-0.81.2-0.5-1.10.00.0
Cu content in liver2.02.44.9-1.2-2.0-2.2-1.21.7-1.7-1.90.00.0
Fe content in liver1.01.33.2-1.8-1.7-1.6-0.30.8-0.8-1.20.00.0
K content in liver0.10.10.40.1-0.3-0.4-0.30.3-0.6-0.30.00.0
Mg content in liver0.30.41.5-0.7-1.2-0.90.40.0-0.4-0.30.00.0
Mn content in liver0.20.30.9-0.9-0.9-0.70.3-0.1-0.3-0.20.00.0
Na content in liver0.40.41.50.1-0.6-0.01.2-1.00.40.70.00.0
Rb content in liver2.52.96.2-0.7-1.6-2.1-1.92.2-2.5-2.10.00.0
Se content in liver0.81.02.6-0.30.00.71.6-1.61.21.30.00.0
Sr content in liver6.85.912.01.83.13.52.0-2.72.73.10.00.0
Zn content in liver1.11.35.1-1.8-2.3-1.51.0-0.30.3-0.40.00.0
Bone: minimum diameter1.32.66.42.41.0-0.3-2.51.9-2.2-1.30.00.0
Time in familiar zone, hab. session 12.02.25.81.92.20.9-2.41.6-1.3-0.70.00.0
Time in novel zone, hab. session 11.71.96.1-1.8-2.5-1.41.9-1.10.80.10.00.0
Total zone transitions, hab. session 11.01.53.81.90.8-0.1-1.71.4-1.8-0.90.00.0
Total locomotion distance, hab. session 10.91.34.32.12.11.3-0.90.3-0.50.40.00.0
Locomotion velocity, hab. session 10.60.82.61.51.61.0-0.70.3-0.60.20.00.0
Time in familiar zone, hab. session 21.21.42.5-0.8-1.3-1.6-1.11.4-1.4-1.60.00.0
Time in novel zone, hab. session 20.40.41.20.1-0.20.31.1-1.00.80.80.00.0
Total zone transitions, hab. session 21.72.24.82.22.00.7-2.11.5-1.9-0.60.00.0
Total locomotion distance, hab. session 21.52.07.22.22.72.1-0.3-0.40.01.10.00.0
Locomotion velocity, hab. session 21.82.48.82.33.02.4-0.3-0.50.11.30.00.0
Novel to familiar place preference ratio0.40.51.70.91.31.0-0.3-0.10.20.50.00.0
Novelty place preference0.20.31.00.71.00.7-0.60.3-0.10.20.00.0
Time in novel zone, NPP test0.10.20.60.60.80.5-0.60.3-0.20.00.00.0
Total zone transitions, NPP test0.30.51.91.11.40.9-0.70.3-0.30.20.00.0
Total locomotion distance, NPP test0.81.14.41.12.11.7-0.2-0.40.30.90.00.0
Locomotion velocity, NPP test0.91.35.61.42.41.8-0.4-0.30.10.90.00.0
Intraocular pressure0.10.20.6-0.1-0.8-0.70.30.2-0.2-0.40.00.0
Delta distance traveled before/after self-admin1.71.83.30.51.21.61.5-1.71.41.81.30.7
Delta ambulatory time before/after self-admin1.11.82.90.01.41.71.3-1.51.61.71.40.7
Parametrial fat weight1.43.27.2-0.31.42.22.0-2.42.72.40.00.0
Pavlov. Cond. lever latency0.00.00.10.0-0.3-0.30.1-0.0-0.0-0.10.00.0
Pavlov. Cond. magazine entry latency0.60.71.70.60.30.71.3-1.31.11.10.00.0
Pavlov. Cond. change in total contacts0.20.20.40.40.50.60.3-0.40.40.50.00.0
Pavlov. Cond. index score0.30.30.60.50.60.80.6-0.70.60.70.00.0
Pavlov. Cond. latency score0.30.30.70.30.70.80.6-0.70.70.70.00.0
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.0-0.0-0.00.1-0.1-0.00.00.0
Pavlov. Cond. magazine entry number0.40.51.4-1.2-0.4-0.6-0.80.9-0.5-0.80.00.0
Pavlov. Cond. intertrial magazine entries0.20.31.00.61.00.5-0.80.5-0.5-0.00.00.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.30.50.70.6-0.70.70.70.00.0
Pavlov. Cond. response bias0.10.10.40.6-0.3-0.00.6-0.50.10.30.00.0
Pavlov. Cond. lever latency2.02.86.9-2.3-2.6-2.5-0.61.4-0.8-1.90.00.0
Pavlov. Cond. magazine entry latency1.01.52.80.91.21.61.2-1.61.21.70.00.0
Pavlov. Cond. change in total contacts0.61.65.62.42.21.6-0.6-0.2-0.20.80.00.0
Pavlov. Cond. index score1.01.53.61.91.91.70.4-1.10.51.40.00.0
Pavlov. Cond. latency score1.21.94.01.52.02.00.8-1.50.91.70.00.0
Pavlov. Cond. lever contacts1.62.36.12.32.52.20.3-1.10.61.60.00.0
Pavlov. Cond. magazine entry number0.70.91.6-1.1-0.9-1.1-0.91.3-0.8-1.30.00.0
Pavlov. Cond. intertrial magazine entries1.43.26.6-0.1-0.9-1.9-2.52.6-2.4-2.40.00.0
Pavlov. Cond. lever-magazine prob. diff.0.91.53.31.81.81.70.4-1.10.51.40.00.0
Pavlov. Cond. response bias1.11.55.82.42.01.6-0.3-0.5-0.01.00.00.0
Time in closed arm before self-admin0.71.27.0-2.6-0.1-0.2-1.01.0-0.9-0.9-0.20.2
Time in closed arm after self-admin0.20.20.8-0.9-0.5-0.6-0.20.4-0.4-0.4-0.3-0.5
Time in open arm before self-admin2.02.510.83.30.91.01.3-1.61.41.61.10.2
Time in open arm after self-admin0.30.42.21.50.50.50.4-0.50.40.5-0.10.0
Bone: periosteal estimation0.92.25.12.00.4-0.7-2.21.9-2.2-1.50.00.0
Bone: periosteal perimeter0.91.84.62.10.0-0.9-1.81.5-1.9-1.40.00.0
Bone: post-yield work1.42.44.70.2-1.7-2.2-1.61.9-2.0-2.10.00.0
Progressive ratio test 1 active lever presses0.30.51.10.50.3-0.0-1.00.9-0.7-0.8-0.9-0.1
Progressive ratio test 1 breakpoint0.30.41.00.50.40.1-1.00.9-0.7-0.7-0.9-0.2
Progressive ratio test 1 inactive lever presses1.33.45.3-2.1-1.5-1.8-1.72.1-2.0-2.3-1.9-0.4
Progressive ratio test 2 active lever presses1.72.411.8-3.4-1.9-1.5-0.30.9-0.8-1.3-0.10.8
Progressive ratio test 2 breakpoint2.12.712.2-3.5-2.1-1.6-0.31.0-0.9-1.5-0.20.7
Progressive ratio test 2 inactive lever presses1.34.17.3-2.7-1.5-1.7-1.92.4-2.2-2.5-2.0-0.5
Incentive Sensitization - Responses1.64.521.0-4.6-2.6-2.2-0.71.5-1.1-2.0-0.40.4
Incentive Sensitization - Breakpoint1.84.119.8-4.4-2.6-2.1-0.51.3-1.0-1.8-0.20.6
Sum of active levers in priming session hrs 5-60.70.72.5-0.81.61.4-0.2-0.20.50.70.5-0.2
Progressive ratio0.30.93.11.81.61.2-0.0-0.40.30.60.3-0.1
Food seeking constrained by brief footshock13.516.860.46.47.86.1-1.8-0.61.02.60.8-0.6
Seeking ratio, punishment vs. effort0.61.34.31.32.11.4-1.40.6-0.30.1-0.4-0.6
Retroperitoneal fat weight1.98.521.9-1.8-1.21.14.4-4.44.73.20.00.0
Reaction time number correct0.41.54.82.21.81.60.3-0.90.21.30.00.0
Reaction time mean minus median0.00.31.3-0.5-1.2-0.90.10.1-0.2-0.40.00.0
Reaction time mean minus median AUC0.10.52.4-0.0-1.6-1.30.20.0-0.3-0.50.00.0
Reaction time num false alarms0.10.20.7-0.90.60.60.1-0.1-0.00.30.00.0
Reaction time num false alarms AUC0.20.51.60.01.31.20.4-0.50.20.80.00.0
Reaction time trials correct on left0.41.54.82.21.81.60.3-0.90.21.30.00.0
Reaction time trials on left0.41.44.52.11.81.60.2-0.90.21.30.00.0
Reaction time mean1.32.87.3-2.7-2.5-2.3-0.41.3-1.3-1.70.00.0
Reaction time mean AUC1.02.47.9-2.8-2.5-2.10.00.8-0.8-1.40.00.0
Median of all reaction times1.92.98.6-2.9-2.5-2.3-0.31.3-1.3-1.70.00.0
Reaction time omissions0.10.10.5-0.20.70.6-0.0-0.00.00.30.00.0
Reaction time false alarm rate0.10.21.3-1.10.30.40.20.00.20.10.00.0
Reaction time premature initiation rate0.10.10.4-0.60.20.30.3-0.10.40.20.00.0
Reaction time premature initiations0.20.51.20.51.01.10.5-0.70.60.90.00.0
Std. dev. reaction times0.41.24.0-2.0-1.6-1.4-0.40.8-0.8-1.10.00.0
Reaction time trials completed0.41.44.52.11.81.60.2-0.90.21.30.00.0
Reaction time trials AUC0.41.44.12.01.71.60.3-1.00.21.30.00.0
Run reversals in cocaine runway, females1.01.18.8-3.0-0.5-0.60.20.3-0.1-0.3-0.2-0.8
Run reversals in cocaine runway, males0.40.41.8-0.0-1.3-1.20.00.3-0.3-0.7-0.20.1
Latency to leave start box in cocaine runway0.50.74.0-2.0-0.2-0.3-0.70.90.1-0.70.2-0.0
Latency to leave start box in cocaine runway, F0.40.53.1-1.80.20.3-0.20.30.7-0.10.80.5
Latency to leave start box in cocaine runway, M1.61.52.6-1.0-1.3-1.5-0.91.5-1.1-1.6-1.0-0.7
Std. dev. time between licks in bursts0.40.73.20.71.81.3-0.5-0.00.10.50.00.0
Total sessions with >9 infusions1.31.62.7-0.0-1.3-1.4-1.11.3-1.6-1.6-1.5-0.2
Short access day 1 total inactive lever presses1.32.66.1-2.2-2.5-2.2-0.71.3-1.0-1.8-1.00.1
Short access day 10 total inactive lever presses0.00.31.6-1.30.0-0.1-0.50.6-0.2-0.4-0.2-0.7
Short access day 1 total infusions0.20.41.30.0-1.1-1.0-0.20.3-0.4-0.7-0.30.4
Short access day 10 total infusions0.20.31.4-0.6-0.9-0.50.10.0-0.4-0.40.01.2
Short access total infusions0.20.21.0-0.0-0.8-0.40.3-0.1-0.1-0.20.21.0
Short access day 1 locomotion1.62.68.4-1.2-2.9-2.6-0.31.0-1.2-1.8-1.00.2
Short access day 10 total locomotion0.31.11.7-0.61.00.3-1.31.3-1.2-0.8-1.3-1.3
Short access total locomotion0.40.61.40.81.20.8-1.00.6-0.7-0.3-0.7-0.3
One hour access (0.3 mA shock)5.16.019.0-4.4-1.9-2.2-1.92.5-2.3-2.6-1.9-1.0
Compulsive drug intake1.72.53.6-1.9-1.3-1.6-1.51.8-1.5-1.9-1.7-0.9
One hour access (shock baseline)0.92.411.9-3.5-2.1-1.60.10.6-0.7-1.2-0.10.6
Social response proportion2.32.912.8-3.6-2.1-1.9-0.71.3-0.4-1.70.00.0
Social responses2.93.96.3-2.4-2.1-2.4-1.82.4-2.0-2.50.00.0
Social time1.52.47.50.92.00.7-2.72.1-1.7-1.10.00.0
Soleus weight0.10.20.90.41.00.80.0-0.30.50.40.00.0
Bone: stiffness0.91.64.4-0.2-0.1-0.9-2.12.0-1.6-1.70.00.0
Tibialis anterior weight0.93.05.81.41.62.11.6-2.42.12.30.00.0
Time to tail flick, vehicle, before self-admin0.30.41.7-0.11.31.0-0.60.30.00.10.10.1
Time to tail flick, vehicle, after self-admin0.81.74.1-1.9-2.0-2.00.00.9-0.5-1.2-0.4-0.8
Time to tail flick, test, before self-admin3.33.813.23.13.62.8-1.0-0.20.61.20.0-0.8
Time to tail flick, test, after self-admin0.20.20.60.00.00.20.7-0.50.80.50.2-0.0
Delta time to tail flick, vehicle, before/after SA1.11.24.7-1.0-2.2-1.90.40.4-0.1-0.8-0.2-0.4
Delta time to tail flick, test, before/after SA1.62.06.7-2.3-2.6-2.00.80.2-0.3-0.8-0.20.2
Tibia length1.44.010.11.00.5-1.0-3.22.9-3.2-2.20.00.0
Ambulatory time before self-admin1.02.97.32.72.41.4-2.21.1-1.3-0.4-1.4-1.1
Ambulatory time after self-admin2.74.416.63.04.13.2-1.1-0.30.51.3-0.0-0.6
Bone: tissue strength1.81.98.90.83.02.4-0.6-0.10.60.90.00.0
Total heroin consumption0.10.20.40.30.60.7-0.0-0.30.30.40.40.4
Bone: trabecular number0.61.17.52.70.60.50.5-0.80.30.70.00.0
Bone: trabecular spacing0.00.00.1-0.10.30.3-0.10.00.10.10.00.0
Bone: trabecular thickness0.10.10.5-0.1-0.7-0.60.2-0.10.2-0.20.00.0
Bone: trabecular tissue density1.01.87.6-2.8-2.0-1.01.4-0.71.20.10.00.0
Water consumed over 24 hours0.30.71.70.81.30.6-1.30.9-0.8-0.40.00.0
Number of responses in last shaping day1.92.57.9-2.8-2.7-2.10.60.5-0.5-1.2-0.20.9