Zfp260

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	mRNA stability	Zfp260	0.03	0.03	3.3e-04	0.02	0.02	0.02	0.02	1.5e-03	1.6e-03	3.8e-03	2.2e-03
2	Brain	gene expression	Zfp260	0.03	0.03	1.1e-03	0.02	0.02	0.02	0.02	3.9e-03	6.4e-03	4.1e-03	5.1e-03
3	Liver	gene expression	Zfp260	0.02	0.02	9.1e-03	0.01	0	-0	0	1.5e-02	7.3e-02	4.4e-01	7.8e-02
4	NAcc	gene expression	Zfp260	0.06	0.04	6.3e-05	0.02	0.03	0.02	0.03	3.4e-03	1.6e-04	1.3e-03	6.3e-04
5	IL	gene expression	Zfp260	1.3	0	7.3e-03	0.01	-0.01	-0.01	NA	2.3e-01	4.7e-01	7.1e-01	NA

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5
Bone: apparent density	0.3	0.6	2.6	-0.2	-0.3	0.2	1.6	-0.4
Area under the delay curve	0.9	1.0	1.5	-1.2	-1.1	1.0	-0.1	1.0
BMI with tail	0.2	0.5	0.8	0.9	0.7	-0.9	-0.7	-0.3
BMI without tail	0.1	0.3	0.6	-0.8	-0.5	0.6	0.2	-0.4
Body weight	2.1	8.9	12.2	-3.3	-3.2	3.0	3.5	1.5
Weight adjusted by age	0.1	0.2	0.4	0.4	0.4	-0.4	0.6	0.1
Bone surface	1.0	1.8	3.7	-1.1	-1.2	1.0	1.9	1.2
Bone volume	0.9	1.5	4.0	-1.0	-1.0	0.9	2.0	0.9
Breakpoint value in progressive ratio session	2.7	3.0	4.8	-2.2	-2.0	2.2	0.4	1.2
Number of licking bursts	2.9	3.4	4.7	2.0	2.0	-2.2	-2.1	0.2
Context. condit. distance diff. score	0.2	0.3	1.2	0.1	0.0	0.0	-0.3	1.1
Locomotion velocity, session 1	0.7	0.7	1.3	0.9	0.9	-0.9	-0.4	-1.2
Locomotion distance, session 1	0.5	0.7	1.5	-0.7	-0.7	0.7	0.6	1.2
Locomotion velocity, session 2	0.3	0.4	0.7	0.3	0.4	-0.4	-0.9	-0.8
Locomotion distance, session 2	1.1	1.5	2.0	1.3	1.4	-1.4	-1.4	0.3
Locomotion velocity, session 3	0.2	0.3	0.4	0.6	0.6	-0.6	-0.5	-0.2
Locomotion distance, session 3	3.6	3.9	6.3	-2.0	-2.0	2.0	1.1	2.5
Stereotopy head waving bouts, day 3	1.6	1.9	5.4	1.1	1.1	-1.1	-0.4	-2.3
Stereotopy head waving duration, day 3	2.4	2.9	6.5	1.5	1.5	-1.5	-0.9	-2.6
Locomotion velocity, session 7	0.4	0.4	1.7	-0.3	-0.4	0.4	0.4	1.3
Locomotion distance, session 7	0.1	0.1	0.4	-0.2	-0.2	0.2	0.5	0.6
Stereotopy head waving bouts, day 7	0.7	0.8	2.0	0.8	0.8	-0.8	-1.4	0.1
Stereotopy head waving duration, day 7	1.8	2.1	3.5	1.5	1.5	-1.5	-1.9	-0.8
Locomotion velocity, session 8	3.4	4.0	5.2	2.3	2.2	-2.2	-2.2	-0.1
Locomotion distance, session 8	0.8	1.2	1.8	1.0	0.9	-0.9	-1.3	1.3
Degree of sensitization distance	0.9	0.9	1.4	1.0	1.0	-1.0	-0.2	-1.2
Degree of sensitization stereotypy	1.0	1.1	2.6	1.0	1.0	-1.0	-1.6	0.5
Conditioned locomotion	0.4	0.4	1.4	0.4	0.4	-0.6	-1.2	-0.2
Cocaine response after cond. corrected	0.5	0.6	2.9	-0.1	-0.1	0.2	-0.1	-1.7
Cocaine response after cond. not corrected	0.8	0.9	4.2	-0.1	-0.2	0.1	0.3	-2.0
Cocaine response before conditioning	0.8	1.0	2.8	-0.8	-0.9	0.7	1.7	0.6
Saline control response	0.1	0.2	0.4	-0.4	-0.4	0.3	0.0	-0.6
Bone: connectivity density	0.1	0.2	1.1	0.0	0.0	-0.1	1.1	-0.2
Bone: cortical apparent density	1.8	2.3	3.6	1.7	1.7	-1.9	-1.5	-0.3
Bone: cortical area	1.1	1.6	2.1	-1.5	-1.5	1.2	1.4	0.6
Bone: cortical porosity	2.0	2.2	3.5	1.9	1.8	-1.6	-1.4	0.2
Bone: cortical porosity	2.4	2.6	3.8	2.0	1.9	-1.7	-1.6	0.4
Bone: cortical thickness	0.2	0.3	0.5	-0.7	-0.7	0.4	0.7	-0.3
Bone: cortical thickness	0.9	1.1	1.4	1.1	1.1	-1.2	-0.7	-1.1
Bone: cortical tissue density	2.0	2.7	4.1	1.8	1.8	-2.0	-1.6	-0.3
Condit. Reinf. active minus inactive responses	0.1	0.1	0.3	0.3	0.3	-0.3	-0.5	-0.3
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.9	0.2	0.2	-0.2	-0.3	-1.4
Condit. Reinf. active responses	1.5	1.8	3.0	1.4	1.4	-1.4	-1.7	-0.4
Condit. Reinf. inactive responses	1.7	2.1	3.5	1.5	1.5	-1.5	-1.9	0.6
Incentive salience index mean	0.1	0.1	0.3	0.2	0.1	-0.1	-0.6	-0.1
Condit. Reinf. lever presses	0.1	0.2	0.2	-0.4	-0.5	0.5	-0.2	0.5
Condit. Reinf. active minus inactive responses	2.5	3.1	4.8	-2.2	-2.2	2.1	1.0	0.4
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.3	-0.6	-0.6	0.6	-0.5	-0.2
Condit. Reinf. active responses	3.9	5.3	7.3	-2.7	-2.7	2.6	1.9	1.4
Condit. Reinf. inactive responses	3.6	4.4	4.6	-2.1	-2.1	2.0	2.1	2.2
Condit. Reinf. lever presses	7.0	9.4	12.7	-3.5	-3.6	3.4	2.9	1.3
Condit. Reinf. lever reinforcers received	4.0	5.7	7.4	-2.7	-2.7	2.6	1.9	1.8
Conditioned reinforcement - actives	0.2	0.2	0.4	0.2	0.4	-0.6	-0.5	-0.3
Conditioned reinforcement - inactives	1.2	1.3	4.0	-1.1	-1.0	0.6	-0.1	2.0
Conditioned locomotion	2.3	2.7	3.9	2.0	1.8	-1.7	-1.9	-0.2
Patch foraging indifference point 0 sec	0.0	0.0	0.1	-0.1	-0.0	0.1	0.2	0.3
Patch foraging indifference point AUC	0.4	0.4	0.8	0.4	0.6	-0.8	-0.5	-0.9
Delay disc. indifference point, 0s delay	1.6	1.8	4.3	-1.5	-1.1	0.7	-0.8	2.1
Delay disc. indifference point, 16s delay	2.3	2.3	3.9	-2.0	-1.8	1.8	-0.0	1.1
Delay disc. indifference point, 2s delay	1.5	1.6	3.2	-1.5	-1.3	0.8	0.4	1.8
Delay disc. indifference point, 24s delay	2.7	2.6	3.3	-1.7	-1.7	1.8	1.2	1.6
Delay disc. indifference point, 4s delay	0.2	0.2	0.6	-0.4	-0.3	0.3	-0.8	0.3
Delay disc. indifference point, 8s delay	0.1	0.1	0.4	-0.0	-0.2	0.4	0.4	0.6
Indifference point function ln k	0.4	0.5	1.3	-0.5	-0.7	1.1	0.6	0.5
Indifference point function log k	0.4	0.5	1.3	-0.5	-0.7	1.1	0.6	0.5
Patch foraging total patch changes 0 sec	0.1	0.1	0.2	-0.2	-0.2	0.3	0.4	0.5
Patch foraging total patch changes 12 sec	0.2	0.2	0.5	-0.6	-0.4	0.3	-0.2	-0.7
Patch foraging total patch changes 18 sec	0.2	0.3	0.6	0.4	0.6	-0.8	0.0	0.5
Patch foraging total patch changes 24 sec	1.0	1.3	3.0	-1.1	-1.0	0.7	0.8	1.7
Patch foraging total patch changes 6 sec	0.0	0.1	0.1	-0.0	0.1	-0.3	0.2	-0.3
Patch foraging time to switch 0 sec	0.4	0.6	1.6	0.5	0.3	-0.5	-0.8	-1.3
Patch foraging water rate 0 sec	0.9	1.4	2.3	1.4	1.5	-1.4	-0.9	-0.2
Patch foraging water rate 12 sec	0.5	0.8	2.1	-0.6	-0.7	0.5	0.8	1.4
Patch foraging water rate 18 sec	0.3	0.4	0.8	0.8	0.9	-0.7	-0.4	-0.1
Patch foraging water rate 24 sec	0.7	0.9	4.2	0.1	0.1	-0.1	-0.5	2.1
Patch foraging water rate 6 sec	1.0	1.4	4.3	-0.3	-0.8	0.9	1.1	2.1
Seeking ratio, delayed vs. immediate footshock	2.0	2.3	5.4	-1.4	-1.5	1.3	0.7	2.3
Distance traveled before self-admin	0.4	0.4	0.9	-0.9	-0.7	0.7	-0.3	0.1
Distance traveled after self-admin	3.7	4.1	6.2	-2.5	-2.3	2.1	1.8	1.1
Extensor digitorum longus weight	0.2	0.7	1.6	0.8	0.8	-0.8	-0.3	-1.3
Bone: elastic displacement	0.1	0.1	0.4	0.2	0.3	-0.3	0.1	-0.6
Bone: elastic work	1.3	1.6	2.3	-1.4	-1.3	1.4	1.5	0.5
Bone: endosteal estimation	1.5	3.4	4.0	-1.9	-2.0	2.0	1.8	1.4
Bone: endosteal perimeter	1.8	3.7	4.7	-2.1	-2.2	2.1	1.5	1.7
Epididymis fat weight	0.1	0.2	0.4	0.2	-0.2	-0.0	0.7	0.5
Delta time in closed arm before/after self-admin	1.8	1.7	3.6	-0.9	-1.2	1.5	1.9	0.9
Delta time in open arm before/after self-admin	0.9	0.9	1.2	0.9	0.9	-1.0	-0.5	-1.1
Diff in mean of infusions in LGA sessions	0.4	0.5	1.9	-0.5	-0.3	0.4	-1.4	0.2
Delay discount exponential model param	0.9	0.9	1.4	1.2	1.1	-1.0	-0.1	-0.9
Extinction: sum of active levers before priming	2.7	2.7	4.6	-1.3	-1.6	2.1	2.1	-0.0
Active lever presses in extinction session 6	2.8	2.7	3.6	-1.7	-1.7	1.9	1.9	-0.6
Bone: final force	1.0	1.7	2.6	-1.2	-1.3	1.3	1.6	0.9
Bone: final moment	1.4	2.3	3.4	-1.5	-1.6	1.6	1.8	0.9
Food consumed during 24 hour testing period	0.9	1.1	2.5	-1.0	-1.0	0.9	0.6	1.6
Glucose	0.2	0.4	0.8	0.6	0.6	-0.5	-0.1	-0.9
Heart weight	0.3	0.5	1.2	-0.4	-0.6	0.7	0.1	1.1
Delay discount hyperbolic model param	0.7	0.8	1.2	1.1	1.0	-0.8	0.0	-1.0
Intermittent access intake day 1-15 change	1.8	1.8	2.6	-1.2	-1.2	1.2	1.6	1.3
Intermittent access intake escalation	1.9	1.9	2.4	-1.2	-1.2	1.2	1.5	1.5
Intermittent access intake escalation 2	1.8	1.8	2.7	-1.6	-1.5	1.4	1.2	0.7
Intermitt. access day 1 inactive lever presses	3.0	3.2	5.2	-1.7	-1.9	2.3	1.9	0.7
Intermitt. access day 15 inactive lever presses	0.8	0.9	1.3	-1.1	-1.0	1.0	0.2	1.1
Intermitt. access escalation Index	0.3	0.2	0.7	0.1	0.2	-0.2	-0.6	0.8
Intermittent access day 1 total infusions	2.1	2.4	4.3	1.5	1.6	-1.6	-2.1	0.7
Intermittent access day 15 total infusions	0.8	0.9	3.6	-0.3	-0.1	0.0	-0.8	1.9
Intermittent access terminal intake (last 3 days)	0.7	0.8	2.4	-0.2	0.1	-0.1	-1.2	1.5
Intermittent access total infusions	0.8	0.9	1.8	0.4	0.6	-0.5	-1.4	1.3
Intermittent access day 1 locomotion	1.2	1.3	2.3	1.0	1.0	-0.9	-1.5	1.0
Intermittent access day 15 total locomotion	0.7	0.7	3.1	0.4	0.5	-0.3	-0.4	1.8
Intermittent access total locomotion	1.1	1.3	2.2	1.2	1.3	-1.0	-1.5	0.6
Intermittent access standard deviation	5.3	5.6	6.5	-2.5	-2.4	2.4	1.9	2.5
Left kidney weight	1.9	5.3	12.5	-1.9	-2.3	2.2	3.5	0.3
Right kidney weight	3.7	10.5	18.6	-3.2	-3.4	3.5	4.3	0.8
Cocaine induced anxiety	0.5	0.6	1.1	-0.8	-0.8	1.1	0.8	-0.0
Post-drug Anxiety	0.3	0.3	0.7	-0.6	-0.4	0.2	-0.4	-0.8
Baseline Anxiety	1.0	1.0	1.7	0.8	1.0	-1.3	-1.3	-0.3
Tail length	4.1	12.4	17.0	-4.1	-3.8	4.0	3.7	1.2
Length with tail	6.7	24.7	31.6	-5.6	-5.3	5.2	5.3	2.8
Length without tail	3.9	8.5	12.8	-2.8	-2.9	2.7	3.6	2.5
Times rat made contact with spout	1.2	1.4	2.1	1.4	1.4	-1.4	-0.2	-1.1
Lifetime Intake	0.8	0.9	1.5	0.8	0.9	-0.8	-1.2	0.8
Liver weight, left	0.9	1.5	2.2	1.3	1.4	-1.2	-0.4	-1.5
Liver weight, right	0.3	0.6	2.0	0.3	0.6	-0.6	-0.2	-1.4
Locomotor activity	1.1	1.8	5.9	1.0	1.0	-1.0	-0.2	-2.4
Locomotor testing distance	0.7	1.2	2.8	1.1	0.9	-0.9	-0.2	-1.7
Locomotor testing rearing	1.8	2.7	4.5	1.8	1.6	-2.1	-1.4	-1.2
Locomotion in novel chamber	0.2	0.3	1.1	0.2	0.1	0.1	-0.5	-1.0
Locomotion in novel chamber post-restriction	0.5	0.6	1.2	-0.9	-0.9	1.1	-0.4	-0.2
Fecal boli incidents, locomotor time 1	1.7	1.8	2.7	1.3	1.1	-0.9	-1.6	-1.6
Change in fecal boli incidents, locomotor task	0.4	0.4	1.1	-0.5	-0.3	0.3	0.5	-1.0
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	0.2	0.2	0.1	-0.1	-0.3
Bouts of movement, locomotor time 1	1.6	1.8	3.3	-1.8	-1.4	1.0	-0.2	1.6
Total resting periods, locomotor time 1	1.6	1.7	3.5	-1.9	-1.5	1.1	-0.2	1.3
Rest time, locomotor task time 1	0.7	0.7	2.1	0.3	0.2	-0.3	-1.4	-1.2
Distance moved, locomotor task time 1	0.2	0.2	0.6	0.0	0.3	-0.4	0.4	0.8
Vertical activity count, locomotor time 1	1.4	1.4	2.9	-0.8	-0.9	0.9	1.7	1.4
Time >=10cm from walls, locomotor time 2	1.0	1.1	3.3	0.5	0.7	-0.9	-1.8	-0.8
Bouts of movement, locomotor time 2	0.1	0.1	0.3	-0.5	-0.4	0.1	-0.4	0.2
Total resting periods, locomotor time 2	0.1	0.1	0.2	-0.3	-0.2	0.0	-0.5	-0.1
Rest time, locomotor task time 2	0.3	0.4	0.8	0.3	0.2	-0.2	-0.9	-0.9
Distance moved, locomotor task time 2	0.3	0.4	1.0	0.2	0.5	-1.0	-0.2	0.8
Vertical activity count, locomotor time 2	0.8	0.9	1.8	-0.9	-0.8	0.6	0.9	1.3
Light reinforcement 1	0.2	0.4	0.7	0.8	0.5	-0.8	-0.4	0.3
Light reinforcement 2	2.4	3.3	4.9	2.2	1.9	-1.9	-1.7	-1.1
Bone: marrow area	1.6	3.4	4.1	-1.9	-2.0	2.0	1.9	1.4
Bone: maximum diameter	1.2	2.2	2.9	-1.7	-1.7	1.4	1.6	1.0
Bone: maximum force	1.9	3.3	4.1	-1.9	-1.9	1.9	2.0	1.3
Bone: maximum moment	2.4	4.2	4.8	-2.1	-2.2	2.2	2.2	1.4
Mean time between licks in bursts	0.1	0.1	0.2	-0.3	-0.4	0.4	-0.2	0.2
Mean num. licks in bursts	1.0	1.1	2.7	-0.8	-0.9	1.0	1.7	-0.8
Cd content in liver	0.1	0.1	0.3	0.4	0.2	-0.2	0.5	-0.1
Co content in liver	0.4	0.5	0.9	1.0	0.7	-0.7	-0.3	-0.6
Cu content in liver	0.3	0.3	0.5	-0.6	-0.4	0.4	0.7	0.7
Fe content in liver	0.0	0.0	0.0	0.1	0.1	-0.1	-0.2	0.1
K content in liver	0.1	0.1	0.2	-0.4	-0.3	0.3	0.0	-0.1
Mg content in liver	0.6	0.6	1.2	0.5	0.7	-0.7	-0.7	-1.1
Mn content in liver	1.4	1.6	3.3	1.1	1.2	-1.2	-0.8	-1.8
Na content in liver	2.6	2.7	3.6	-1.9	-1.9	1.9	0.8	1.5
Rb content in liver	0.2	0.2	0.5	0.2	0.1	-0.1	-0.6	0.7
Se content in liver	7.8	9.5	12.1	3.5	3.3	-3.3	-2.8	-2.4
Sr content in liver	0.8	0.7	1.1	1.0	0.8	-0.8	-0.7	-1.1
Zn content in liver	0.1	0.1	0.2	0.4	0.3	-0.3	-0.2	-0.2
Bone: minimum diameter	3.6	6.7	8.6	-2.8	-2.9	2.8	1.9	2.4
Time in familiar zone, hab. session 1	0.4	0.4	0.7	-0.5	-0.5	0.5	0.8	-0.7
Time in novel zone, hab. session 1	1.1	1.1	2.5	1.0	1.0	-1.0	-1.6	0.3
Total zone transitions, hab. session 1	0.1	0.2	0.5	-0.2	-0.2	0.2	-0.4	0.7
Total locomotion distance, hab. session 1	1.4	1.9	3.0	-1.7	-1.7	1.7	0.7	0.6
Locomotion velocity, hab. session 1	0.8	1.2	1.8	-1.3	-1.3	1.3	0.7	0.2
Time in familiar zone, hab. session 2	1.9	2.0	2.7	-1.6	-1.6	1.6	1.4	-0.3
Time in novel zone, hab. session 2	1.4	1.4	1.9	1.3	1.4	-1.4	-1.1	-0.2
Total zone transitions, hab. session 2	2.0	2.6	5.2	1.5	1.6	-1.6	-2.3	-0.7
Total locomotion distance, hab. session 2	0.1	0.2	0.7	0.0	0.0	-0.0	-0.8	0.4
Locomotion velocity, hab. session 2	0.1	0.2	0.7	0.2	0.2	-0.2	-0.8	0.1
Novel to familiar place preference ratio	0.3	0.3	0.4	-0.6	-0.5	0.5	0.1	0.7
Novelty place preference	0.2	0.2	0.6	-0.5	-0.4	0.4	0.0	0.8
Time in novel zone, NPP test	0.1	0.1	0.5	-0.3	-0.2	0.2	-0.2	0.7
Total zone transitions, NPP test	0.1	0.1	0.2	0.5	0.5	-0.5	-0.2	-0.1
Total locomotion distance, NPP test	1.8	2.4	3.0	-1.7	-1.7	1.7	1.7	0.5
Locomotion velocity, NPP test	1.9	2.7	3.4	-1.8	-1.8	1.8	1.8	0.4
Intraocular pressure	0.1	0.1	0.3	-0.4	-0.2	0.2	-0.3	0.6
Delta distance traveled before/after self-admin	3.2	3.5	5.4	-1.9	-1.9	1.7	2.3	1.3
Delta ambulatory time before/after self-admin	3.3	3.6	6.7	-1.6	-1.7	1.6	2.6	1.8
Parametrial fat weight	1.3	2.5	9.0	1.1	0.9	-1.0	0.9	-3.0
Pavlov. Cond. lever latency	0.2	0.2	0.3	-0.5	-0.4	0.4	0.6	0.3
Pavlov. Cond. magazine entry latency	0.5	0.6	0.7	0.8	0.8	-0.8	-0.7	-0.8
Pavlov. Cond. change in total contacts	0.2	0.3	0.8	0.3	0.2	-0.2	-0.9	0.5
Pavlov. Cond. index score	0.5	0.7	0.7	0.9	0.8	-0.8	-0.9	-0.8
Pavlov. Cond. latency score	0.2	0.3	0.5	0.5	0.4	-0.4	-0.7	-0.5
Pavlov. Cond. lever contacts	0.0	0.0	0.1	-0.2	-0.3	0.3	-0.2	-0.1
Pavlov. Cond. magazine entry number	0.6	0.7	0.8	-0.9	-0.9	0.9	0.9	0.7
Pavlov. Cond. intertrial magazine entries	0.3	0.3	0.9	0.4	0.4	-0.4	-1.0	-0.4
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.8	1.0	1.0	0.9	-0.9	-1.0	-0.7
Pavlov. Cond. response bias	0.3	0.3	1.0	0.4	0.4	-0.4	-0.4	-1.0
Pavlov. Cond. lever latency	4.6	6.2	7.7	2.7	2.8	-2.7	-2.4	-1.7
Pavlov. Cond. magazine entry latency	2.8	3.3	4.5	-2.0	-2.1	2.1	1.6	1.0
Pavlov. Cond. change in total contacts	8.5	11.7	14.4	-3.7	-3.8	3.8	2.9	2.8
Pavlov. Cond. index score	4.9	6.2	7.7	-2.7	-2.8	2.7	2.3	1.8
Pavlov. Cond. latency score	4.7	5.8	7.3	-2.7	-2.7	2.7	2.2	1.7
Pavlov. Cond. lever contacts	4.3	5.8	7.1	-2.6	-2.7	2.6	2.2	1.9
Pavlov. Cond. magazine entry number	3.7	4.5	5.4	2.3	2.3	-2.3	-2.1	-1.5
Pavlov. Cond. intertrial magazine entries	1.6	2.1	3.3	1.8	1.8	-1.8	-0.7	-0.6
Pavlov. Cond. lever-magazine prob. diff.	4.6	5.8	7.2	-2.6	-2.7	2.6	2.3	1.6
Pavlov. Cond. response bias	5.1	6.9	8.1	-2.8	-2.8	2.8	2.3	2.3
Time in closed arm before self-admin	1.8	2.0	5.1	0.9	1.1	-1.7	-2.2	-0.0
Time in closed arm after self-admin	0.5	0.6	0.8	-0.9	-0.9	0.7	-0.4	0.7
Time in open arm before self-admin	3.1	3.4	7.4	-1.5	-1.7	2.0	2.7	0.6
Time in open arm after self-admin	0.6	0.7	3.2	-0.1	-0.2	0.5	1.8	0.1
Bone: periosteal estimation	1.8	3.7	4.5	-2.1	-2.1	2.0	2.0	1.3
Bone: periosteal perimeter	1.7	2.8	4.3	-2.0	-2.1	1.9	1.3	0.6
Bone: post-yield work	1.9	2.6	4.1	-1.7	-1.6	1.5	1.2	2.0
Progressive ratio test 1 active lever presses	0.8	0.8	3.6	-0.2	-0.3	0.5	0.2	1.9
Progressive ratio test 1 breakpoint	0.9	0.9	3.1	-0.5	-0.6	0.8	0.5	1.8
Progressive ratio test 1 inactive lever presses	1.0	1.1	2.6	-1.1	-1.0	0.7	-0.0	1.6
Progressive ratio test 2 active lever presses	0.4	0.5	1.8	-0.4	-0.3	0.2	-0.5	1.3
Progressive ratio test 2 breakpoint	0.3	0.3	1.3	-0.2	-0.1	0.1	-0.5	1.2
Progressive ratio test 2 inactive lever presses	2.9	3.3	6.1	-2.0	-1.8	1.7	-0.6	2.5
Incentive Sensitization - Responses	0.1	0.1	0.3	-0.2	-0.1	0.1	-0.6	0.5
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	-0.1	-0.0	-0.0	-0.5	0.5
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.4	-0.1	-0.1	0.6	0.4	0.2
Progressive ratio	0.0	0.0	0.1	0.2	-0.1	0.3	0.1	-0.1
Food seeking constrained by brief footshock	2.7	3.4	4.4	-2.0	-2.1	2.1	1.8	1.0
Seeking ratio, punishment vs. effort	0.7	0.8	1.5	-1.2	-1.0	0.7	0.5	1.0
Retroperitoneal fat weight	1.8	5.9	7.7	2.7	2.4	-2.7	-1.3	-2.8
Reaction time number correct	0.2	0.3	0.6	0.8	0.7	-0.6	0.3	-0.2
Reaction time mean minus median	0.3	0.3	1.1	-0.4	0.1	0.2	1.1	0.6
Reaction time mean minus median AUC	0.5	0.6	2.5	-0.3	0.1	0.1	1.6	0.7
Reaction time num false alarms	0.9	1.2	1.9	1.4	1.3	-1.3	-0.9	-0.3
Reaction time num false alarms AUC	1.1	1.6	2.5	1.6	1.4	-1.4	-1.0	-0.5
Reaction time trials correct on left	0.2	0.3	0.6	0.8	0.7	-0.6	0.3	-0.2
Reaction time trials on left	0.3	0.4	0.6	0.8	0.7	-0.7	0.3	-0.3
Reaction time mean	0.2	0.3	0.8	0.3	0.4	-0.2	0.8	0.9
Reaction time mean AUC	0.3	0.4	0.6	0.5	0.6	-0.4	0.8	0.6
Median of all reaction times	0.2	0.3	0.5	0.5	0.5	-0.3	0.5	0.7
Reaction time omissions	0.4	0.5	1.2	0.7	1.1	-0.9	0.4	-0.4
Reaction time false alarm rate	0.4	0.6	1.0	0.9	0.8	-0.7	-1.0	-0.2
Reaction time premature initiation rate	0.2	0.3	0.9	-0.5	-0.1	0.3	-0.2	0.9
Reaction time premature initiations	0.1	0.1	0.6	-0.1	0.3	-0.2	-0.1	0.8
Std. dev. reaction times	0.5	0.7	1.9	-0.2	0.1	0.1	1.3	1.4
Reaction time trials completed	0.3	0.4	0.6	0.8	0.7	-0.7	0.3	-0.3
Reaction time trials AUC	0.4	0.5	0.9	1.0	0.9	-0.8	0.3	-0.6
Run reversals in cocaine runway, females	0.4	0.4	1.1	0.3	0.2	-0.1	1.0	1.0
Run reversals in cocaine runway, males	1.7	1.6	5.6	1.1	0.9	-0.4	0.7	-2.4
Latency to leave start box in cocaine runway	0.4	0.4	1.8	0.2	0.2	-0.2	0.3	1.4
Latency to leave start box in cocaine runway, F	0.4	0.4	0.9	0.6	0.6	-0.6	0.0	1.0
Latency to leave start box in cocaine runway, M	0.1	0.1	0.1	-0.4	-0.2	-0.0	0.2	0.4
Std. dev. time between licks in bursts	1.5	1.8	2.4	-1.5	-1.5	1.5	-0.4	1.3
Total sessions with >9 infusions	1.7	1.9	3.1	1.7	1.8	-1.5	-0.9	-0.7
Short access day 1 total inactive lever presses	1.3	1.4	3.5	-1.2	-1.1	0.7	-0.6	1.9
Short access day 10 total inactive lever presses	2.3	2.6	3.6	-1.9	-1.8	1.9	0.8	1.4
Short access day 1 total infusions	0.1	0.1	0.3	0.3	0.4	-0.3	-0.5	0.2
Short access day 10 total infusions	0.9	1.0	2.1	1.4	1.3	-0.8	-0.6	0.2
Short access total infusions	1.3	1.4	2.5	1.6	1.5	-1.2	-0.9	-0.4
Short access day 1 locomotion	1.3	1.4	3.1	1.8	1.5	-1.3	-0.1	-0.3
Short access day 10 total locomotion	0.6	0.6	1.6	-0.3	-0.5	1.0	0.6	1.3
Short access total locomotion	1.3	1.3	2.2	1.5	1.5	-1.1	-0.9	-0.5
One hour access (0.3 mA shock)	1.3	1.6	4.3	-1.2	-1.0	1.0	0.4	2.1
Compulsive drug intake	0.4	0.4	1.3	-1.1	-0.8	0.1	-0.0	0.1
One hour access (shock baseline)	0.3	0.3	1.4	-0.0	-0.1	0.2	-0.4	1.2
Social response proportion	2.1	2.3	3.5	-1.9	-1.7	1.8	1.1	0.9
Social responses	0.5	0.7	1.1	-1.0	-1.0	0.9	0.8	0.2
Social time	2.5	3.3	5.9	-1.6	-1.6	1.6	1.7	2.4
Soleus weight	0.4	1.1	1.9	1.4	1.2	-1.1	-0.2	-0.7
Bone: stiffness	1.1	1.7	2.0	-1.4	-1.4	1.4	1.3	1.0
Tibialis anterior weight	0.1	0.5	1.7	0.5	0.4	-0.5	0.2	-1.3
Time to tail flick, vehicle, before self-admin	0.7	0.8	1.2	1.0	0.8	-1.0	-1.1	-0.1
Time to tail flick, vehicle, after self-admin	0.4	0.5	1.1	-1.0	-0.8	0.5	-0.3	-0.4
Time to tail flick, test, before self-admin	1.2	1.2	2.1	0.9	0.8	-1.3	-0.7	1.5
Time to tail flick, test, after self-admin	0.2	0.2	0.6	0.4	0.3	-0.8	0.1	0.1
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.2	-1.1	-0.8	0.7	0.8	0.1
Delta time to tail flick, test, before/after SA	0.9	0.8	3.6	0.2	0.4	-0.4	0.1	-1.9
Tibia length	2.1	5.8	8.6	-2.2	-2.4	2.5	2.9	1.9
Ambulatory time before self-admin	0.2	0.3	0.4	-0.6	-0.5	0.7	-0.4	-0.2
Ambulatory time after self-admin	6.1	6.7	8.0	-2.8	-2.7	2.8	2.6	2.0
Bone: tissue strength	2.9	2.8	3.4	-1.7	-1.7	1.7	1.5	1.9
Total heroin consumption	0.6	0.7	1.3	-0.9	-0.9	1.1	0.1	0.7
Bone: trabecular number	0.8	1.3	3.3	-0.9	-1.0	0.9	1.8	0.8
Bone: trabecular spacing	0.5	0.6	0.9	-0.9	-0.9	1.0	0.2	-0.5
Bone: trabecular thickness	0.2	0.2	0.5	0.6	0.6	-0.7	0.1	0.1
Bone: trabecular tissue density	2.6	3.6	7.0	1.8	1.8	-1.9	-1.2	-2.6
Water consumed over 24 hours	0.2	0.3	0.7	-0.5	-0.4	0.3	0.9	0.5
Number of responses in last shaping day	0.8	0.8	1.5	-0.9	-0.6	0.4	-1.0	1.2