Hub : Genes

Xrcc6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Xrcc6 0.22 0.13 2.4e-03 0.1 0.07 0.1 0.08 2.6e-03 8.7e-03 2.8e-03 7.4e-03
2 Adipose isoform ratio NM_139080.2 0.19 0.1 1.3e-15 0.1 0.1 0.09 0.1 3.0e-11 4.2e-11 1.1e-09 5.0e-11
3 Adipose alternative TSS NM_139080.2 0.17 0.09 5.6e-17 0.11 0.11 0.11 0.11 4.0e-12 3.2e-12 6.0e-12 5.3e-12
4 Adipose alternative TSS XM_008765671.4 0.17 0.09 1.1e-16 0.11 0.11 0.11 0.11 6.0e-12 4.4e-12 8.6e-12 7.6e-12
5 PL mRNA stability Xrcc6 0.05 0.03 1.6e-06 0.06 0.05 0.04 0.05 3.4e-07 8.2e-06 3.2e-05 3.1e-06
6 Adipose alternative TSS NM_139080.2 0.17 0.09 0.0e+00 0.11 0.11 0.11 0.11 1.2e-12 1.4e-12 3.4e-12 3.0e-12
7 Adipose alternative TSS XM_008765671.4 0.17 0.08 5.6e-17 0.11 0.11 0.11 0.11 1.8e-12 2.0e-12 4.4e-12 3.4e-12
8 NAcc mRNA stability Xrcc6 0.04 0.02 1.7e-08 0.06 0.04 0.05 0.04 4.0e-09 6.7e-07 5.5e-08 4.5e-06
9 Adipose isoform ratio XM_063263006.1 0.06 0.03 2.4e-08 0.05 0.04 0.03 0.04 1.1e-06 2.2e-05 1.3e-04 2.0e-05
10 Brain mRNA stability Xrcc6 0.17 0.08 0.0e+00 0.19 0.19 0.18 0.18 9.5e-18 2.8e-17 1.4e-16 5.6e-17
11 Eye mRNA stability Xrcc6 0.29 0.18 3.6e-03 0.09 0.14 0.07 0.04 2.0e-02 3.3e-03 3.4e-02 8.8e-02
12 Adipose isoform ratio XM_008765671.4 0.04 0.03 7.1e-04 0.02 0.01 0 0.01 2.3e-03 9.8e-03 1.6e-01 3.1e-02
13 Adipose intron excision ratio chr7_115436377_115440288 0.06 0.03 1.4e-07 0.04 0.04 0.04 0.04 1.1e-05 2.4e-05 5.2e-05 3.6e-05
14 Adipose gene expression Xrcc6 0.55 0.12 0.0e+00 0.35 0.35 0.35 0.35 9.6e-40 1.4e-40 6.9e-40 2.2e-40
15 BLA mRNA stability Xrcc6 0.08 0.05 3.4e-04 0.03 0.05 0.07 0.06 6.5e-03 7.8e-04 1.1e-04 6.3e-04
16 Adipose mRNA stability Xrcc6 0.05 0.03 9.6e-04 0.01 0.01 0.01 0.02 8.0e-03 6.7e-03 1.9e-02 3.1e-03
17 pVTA mRNA stability Xrcc6 0.06 0.04 5.9e-06 0.03 0.07 0.06 0.06 1.4e-03 2.8e-06 3.2e-05 2.4e-05
18 NAcc gene expression Xrcc6 0.13 0.06 8.5e-12 0.05 0.09 0.09 0.09 1.1e-07 6.7e-13 4.9e-13 5.3e-13
19 Brain gene expression Xrcc6 0.1 0.05 4.0e-07 0.04 0.06 0.07 0.07 9.4e-05 1.5e-06 9.3e-07 9.3e-07
20 PL gene expression Xrcc6 0.19 0.08 1.4e-15 0.13 0.16 0.16 0.16 8.6e-14 1.2e-16 1.1e-16 1.3e-16
21 BLA gene expression Xrcc6 0.14 0.07 1.0e-04 0.03 0.09 0.08 0.07 7.9e-03 1.6e-05 6.3e-05 8.9e-05
22 OFC gene expression Xrcc6 0.33 0.12 2.3e-05 0.3 0.17 0.25 0.28 5.6e-08 7.0e-05 1.5e-06 1.8e-07
23 IC mRNA stability Xrcc6 0.15 0.09 2.0e-03 0.09 0.05 0.04 0.06 1.6e-04 2.8e-03 6.9e-03 2.1e-03
24 pVTA gene expression Xrcc6 0.06 0.04 3.6e-04 0.04 0.04 0.05 0.04 7.6e-04 6.7e-04 7.9e-05 8.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.20.41.0-0.2-0.6-0.60.7-0.7-0.70.7-0.70.7-0.9-0.70.6-0.60.6-1.00.2-0.5-0.7-0.3-0.4-0.70.10.2-0.3
Area under the delay curve0.20.20.5-0.7-0.5-0.40.4-0.2-0.30.3-0.30.3-0.3-0.40.4-0.40.2-0.60.7-0.0-0.6-0.6-0.5-0.1-0.40.30.2
BMI with tail0.72.65.32.31.72.0-2.02.02.0-2.02.0-2.01.91.9-2.02.0-1.91.1-0.71.50.1-0.3-0.3-0.3-1.00.4-1.4
BMI without tail0.10.21.20.50.20.4-0.40.20.2-0.20.1-0.2-0.00.20.1-0.1-0.1-0.3-0.5-0.30.70.80.60.30.9-0.1-1.1
Body weight0.93.97.32.72.12.5-2.52.42.4-2.42.3-2.42.22.4-2.52.5-2.31.9-1.71.90.60.50.30.2-0.61.1-0.1
Weight adjusted by age0.50.84.8-0.60.40.2-0.2-0.10.0-0.0-0.1-0.1-0.1-0.00.3-0.30.30.1-1.4-0.51.61.61.51.51.20.82.2
Bone surface0.40.84.0-0.7-0.4-0.40.4-0.7-0.70.7-0.50.7-0.8-0.50.6-0.60.8-0.8-1.3-0.70.61.31.10.51.40.92.0
Bone volume0.10.21.0-0.1-0.1-0.10.1-0.3-0.20.2-0.10.3-0.4-0.20.2-0.20.4-0.4-1.0-0.30.20.60.50.20.60.41.0
Breakpoint value in progressive ratio session0.20.20.90.2-0.1-0.00.00.0-0.20.20.10.3-0.00.10.1-0.1-0.2-0.30.70.3-0.7-0.9-0.7-0.9-0.80.3-0.8
Number of licking bursts0.40.62.3-1.5-0.9-0.80.7-0.8-0.80.8-0.80.7-0.9-0.80.9-0.90.7-1.0-0.0-0.6-0.00.10.10.10.51.11.1
Context. condit. distance diff. score5.26.311.32.83.22.9-2.93.03.1-3.13.1-3.03.12.9-2.92.9-2.63.4-2.22.11.50.91.11.4-0.6-0.70.1
Locomotion velocity, session 10.80.94.5-1.00.10.2-0.2-0.1-0.10.1-0.20.1-0.20.00.3-0.30.30.0-1.4-0.31.41.81.51.41.51.02.1
Locomotion distance, session 12.32.98.1-2.9-1.9-1.81.8-2.0-1.91.9-2.02.0-2.0-1.91.9-1.91.9-1.50.1-1.70.41.00.90.91.70.41.8
Locomotion velocity, session 20.30.31.20.30.60.6-0.60.60.6-0.60.4-0.50.20.5-0.30.3-0.30.4-1.10.10.70.90.70.60.50.50.5
Locomotion distance, session 22.23.06.8-2.6-1.9-1.91.8-1.9-1.91.9-2.11.9-2.1-1.81.9-1.91.6-2.61.6-1.0-1.6-1.0-1.1-1.20.11.20.9
Locomotion velocity, session 30.60.72.50.10.30.4-0.40.40.3-0.30.5-0.30.30.3-0.20.20.00.9-1.6-0.21.31.51.51.51.1-0.51.2
Locomotion distance, session 31.41.53.5-1.9-1.3-1.31.3-1.2-1.31.3-1.11.3-1.2-1.31.1-1.11.4-0.2-0.8-1.30.91.31.21.41.5-0.91.3
Stereotopy head waving bouts, day 30.60.71.51.21.01.2-1.21.11.1-1.11.0-1.10.81.1-0.90.9-0.90.4-0.80.80.30.40.40.1-0.10.90.1
Stereotopy head waving duration, day 32.93.46.22.52.32.5-2.42.32.4-2.42.1-2.32.02.2-1.91.9-1.91.5-1.91.41.20.91.00.7-0.21.10.0
Locomotion velocity, session 70.20.20.80.1-0.10.2-0.20.30.2-0.20.4-0.30.50.2-0.60.6-0.10.8-0.8-0.00.40.60.60.90.2-0.0-0.2
Locomotion distance, session 70.30.42.0-0.4-0.8-0.50.5-0.2-0.30.3-0.00.30.1-0.3-0.10.10.10.01.00.2-1.4-1.1-1.0-0.5-1.00.2-0.3
Stereotopy head waving bouts, day 73.03.410.31.61.81.7-1.71.51.6-1.61.5-1.51.31.5-1.51.5-0.92.2-3.20.32.82.82.82.41.7-0.21.2
Stereotopy head waving duration, day 72.42.98.31.91.71.6-1.61.61.6-1.61.4-1.51.21.4-1.51.5-0.92.2-2.90.22.52.42.42.01.4-0.9-0.1
Locomotion velocity, session 81.92.35.51.12.32.0-2.01.91.9-1.91.7-1.81.71.9-1.31.3-1.70.9-1.11.60.90.60.40.4-0.31.41.7
Locomotion distance, session 80.71.01.90.71.41.1-1.11.21.3-1.31.2-1.31.11.1-0.80.8-0.91.3-1.00.70.70.50.70.80.0-0.50.3
Degree of sensitization distance2.93.05.92.31.41.6-1.61.81.8-1.81.8-1.81.81.7-1.81.8-1.90.91.11.9-1.6-2.0-1.8-1.6-2.40.5-1.9
Degree of sensitization stereotypy2.32.58.11.21.51.4-1.41.31.3-1.31.2-1.21.11.2-1.31.3-0.82.0-2.80.22.52.52.42.11.5-0.30.9
Conditioned locomotion0.60.71.40.71.00.8-0.81.11.0-1.00.9-1.10.70.7-0.90.9-0.71.1-0.80.21.00.60.91.20.1-0.4-0.7
Cocaine response after cond. corrected0.10.10.40.40.10.2-0.20.10.1-0.10.30.00.40.2-0.10.1-0.10.4-0.3-0.00.60.40.60.50.3-0.20.0
Cocaine response after cond. not corrected0.10.20.70.40.20.2-0.20.20.2-0.20.3-0.10.30.10.2-0.20.00.3-0.6-0.30.80.50.80.60.5-0.70.0
Cocaine response before conditioning0.10.21.0-0.4-0.1-0.30.3-0.00.0-0.0-0.3-0.1-0.5-0.40.7-0.70.5-0.4-0.3-0.5-0.0-0.10.30.00.2-1.0-0.2
Saline control response0.40.52.0-0.10.70.4-0.40.80.7-0.70.3-0.6-0.10.30.1-0.10.00.5-1.0-0.21.31.01.21.00.9-1.40.6
Bone: connectivity density0.10.10.40.0-0.3-0.30.3-0.4-0.30.3-0.40.4-0.5-0.30.2-0.20.3-0.6-0.0-0.1-0.5-0.1-0.3-0.50.10.5-0.0
Bone: cortical apparent density0.71.02.3-1.5-1.4-1.31.3-1.1-1.21.2-1.01.2-1.2-1.21.2-1.21.1-1.00.8-0.9-0.5-0.2-0.1-0.10.4-0.00.0
Bone: cortical area1.21.83.51.51.61.8-1.81.61.6-1.61.9-1.61.71.7-1.51.5-1.60.9-1.31.30.40.30.30.2-0.61.10.3
Bone: cortical porosity0.30.31.41.20.50.6-0.60.70.7-0.70.5-0.40.50.5-0.50.5-0.40.60.30.20.2-0.00.20.0-0.2-0.3-0.9
Bone: cortical porosity1.11.23.51.91.31.4-1.41.41.4-1.41.2-1.11.21.3-1.21.2-1.11.2-0.50.70.80.50.70.5-0.10.1-0.4
Bone: cortical thickness0.61.02.80.60.50.8-0.80.70.6-0.60.9-0.60.80.8-0.60.6-1.1-0.30.61.3-1.4-1.5-1.5-1.4-1.71.6-0.1
Bone: cortical thickness1.01.14.10.20.90.8-0.80.80.9-0.90.7-0.90.80.9-0.60.6-1.2-0.30.71.4-1.3-1.5-1.6-1.3-1.72.00.4
Bone: cortical tissue density0.70.92.2-1.5-1.4-1.21.2-1.1-1.11.1-0.91.2-1.2-1.21.1-1.11.1-1.00.7-0.8-0.5-0.2-0.1-0.10.40.00.1
Condit. Reinf. active minus inactive responses0.20.21.0-0.7-0.4-0.30.3-0.4-0.30.3-0.10.2-0.3-0.20.4-0.40.2-0.8-0.10.1-1.0-0.6-0.6-0.7-0.40.40.0
Condit. Reinf. active-inactive response ratio0.20.31.00.30.60.6-0.60.50.5-0.50.8-0.60.70.6-0.50.5-0.50.5-1.00.50.10.30.20.2-0.1-0.20.1
Condit. Reinf. active responses1.01.22.4-1.5-1.3-1.21.2-1.1-1.01.0-1.10.9-1.3-1.21.4-1.41.1-1.60.8-0.7-1.3-0.9-0.8-1.0-0.1-0.6-0.6
Condit. Reinf. inactive responses2.12.54.2-1.9-1.8-1.91.9-1.6-1.51.5-1.91.5-2.0-1.82.0-2.01.7-1.71.6-1.4-1.3-1.0-0.8-1.00.1-1.3-1.0
Incentive salience index mean0.50.62.1-1.0-0.8-0.60.6-0.6-0.50.5-0.50.4-0.7-0.60.7-0.70.4-1.30.6-0.1-1.5-1.1-1.0-1.0-0.60.2-0.3
Condit. Reinf. lever presses0.70.92.2-1.2-1.1-1.01.0-0.9-0.80.8-1.00.6-1.2-1.01.1-1.10.9-1.51.1-0.6-1.3-0.9-0.7-0.8-0.2-0.2-0.7
Condit. Reinf. active minus inactive responses0.50.63.3-0.40.00.2-0.20.00.0-0.00.40.00.30.4-0.30.3-0.5-0.70.31.1-1.4-1.1-1.3-1.3-1.11.80.9
Condit. Reinf. active-inactive response ratio0.70.84.80.2-0.00.3-0.30.1-0.10.10.40.10.30.5-0.50.5-0.6-0.50.41.2-1.6-1.2-1.4-1.6-1.22.20.6
Condit. Reinf. active responses0.60.82.70.01.01.0-1.00.80.9-0.91.2-0.91.01.0-0.90.9-1.00.1-0.61.3-0.5-0.3-0.5-0.4-0.71.61.5
Condit. Reinf. inactive responses0.81.12.20.11.41.2-1.21.21.5-1.51.3-1.51.31.1-1.01.0-1.00.8-0.90.90.60.40.40.8-0.20.51.3
Condit. Reinf. lever presses0.20.31.1-0.7-0.5-0.50.5-0.6-0.50.5-0.30.4-0.5-0.40.6-0.60.4-1.00.3-0.0-1.0-0.6-0.7-1.0-0.20.40.2
Condit. Reinf. lever reinforcers received0.40.52.1-0.10.70.7-0.70.50.6-0.60.9-0.70.70.7-0.60.6-0.7-0.1-0.31.1-0.8-0.5-0.7-0.7-0.81.41.0
Conditioned reinforcement - actives0.30.61.50.30.50.9-0.90.90.7-0.71.2-0.71.20.9-0.70.7-1.00.6-0.41.0-0.3-0.2-0.20.0-0.70.9-0.5
Conditioned reinforcement - inactives0.60.93.6-0.20.10.4-0.40.30.2-0.20.5-0.20.50.40.1-0.1-0.7-0.91.51.1-1.8-1.6-1.9-1.8-1.51.20.5
Conditioned locomotion1.51.93.31.51.21.7-1.71.71.5-1.51.7-1.51.71.6-1.51.5-1.80.50.21.6-0.7-1.0-0.8-0.7-1.41.4-1.3
Patch foraging indifference point 0 sec0.30.62.1-0.6-0.8-0.60.6-0.7-0.80.8-0.60.7-0.7-0.61.1-1.10.6-1.40.6-0.3-0.9-0.7-0.7-1.2-0.2-0.0-0.3
Patch foraging indifference point AUC0.40.53.0-1.6-0.9-0.60.6-0.7-0.50.5-0.60.5-0.7-0.60.4-0.40.6-0.80.3-0.30.20.10.20.40.21.21.7
Delay disc. indifference point, 0s delay0.80.91.81.21.11.1-1.11.31.2-1.21.1-1.31.11.0-0.80.8-1.10.9-0.20.8-0.1-0.7-0.3-0.1-0.9-0.6-0.9
Delay disc. indifference point, 16s delay0.80.91.5-1.2-1.2-1.21.2-1.1-1.21.2-1.01.1-1.0-1.11.0-1.01.0-1.01.0-0.7-0.7-0.3-0.4-0.30.20.30.8
Delay disc. indifference point, 2s delay0.10.20.6-0.30.20.2-0.20.40.3-0.30.3-0.30.30.2-0.40.4-0.3-0.00.40.3-0.5-0.8-0.40.1-0.80.3-0.5
Delay disc. indifference point, 24s delay0.60.75.1-0.8-0.8-0.40.4-0.5-0.80.8-0.30.6-0.4-0.40.4-0.40.4-0.3-0.5-0.30.50.70.61.00.71.82.3
Delay disc. indifference point, 4s delay0.30.31.3-0.60.30.2-0.20.20.3-0.30.1-0.20.00.20.2-0.2-0.4-0.70.90.7-1.1-1.0-1.1-1.0-0.90.5-0.1
Delay disc. indifference point, 8s delay0.60.71.4-1.1-1.1-1.01.0-0.7-0.90.9-0.90.9-0.9-0.90.8-0.80.7-1.01.2-0.5-0.8-0.7-0.7-0.2-0.1-0.1-0.5
Indifference point function ln k0.50.93.21.81.31.1-1.11.11.0-1.01.1-1.01.01.0-1.01.0-0.91.2-1.10.60.40.40.30.1-0.0-0.7-0.8
Indifference point function log k0.50.93.21.81.31.1-1.11.11.0-1.01.1-1.01.01.0-1.01.0-0.91.2-1.10.60.40.40.30.1-0.0-0.7-0.8
Patch foraging total patch changes 0 sec0.40.72.2-0.7-0.9-0.80.8-0.9-0.90.9-0.80.8-0.9-0.81.2-1.20.7-1.50.7-0.5-0.8-0.7-0.7-1.2-0.1-0.1-0.4
Patch foraging total patch changes 12 sec0.10.11.2-0.5-0.20.0-0.00.00.0-0.00.1-0.1-0.10.00.1-0.10.0-0.60.10.2-0.3-0.4-0.2-0.4-0.30.41.1
Patch foraging total patch changes 18 sec0.20.31.1-0.8-0.2-0.20.2-0.3-0.20.2-0.30.1-0.2-0.10.7-0.70.1-1.00.70.3-0.9-0.9-0.9-1.1-0.70.70.5
Patch foraging total patch changes 24 sec0.20.31.2-1.1-0.8-0.60.6-0.7-0.50.5-0.60.5-0.7-0.60.7-0.70.7-0.70.1-0.50.20.10.10.00.2-0.10.8
Patch foraging total patch changes 6 sec0.30.53.1-1.1-0.3-0.20.2-0.4-0.40.4-0.40.2-0.6-0.31.0-1.00.3-1.80.60.0-0.4-0.7-0.5-0.9-0.31.11.3
Patch foraging time to switch 0 sec0.20.32.50.7-0.3-0.20.3-0.1-0.10.1-0.20.2-0.2-0.30.2-0.20.40.3-0.2-0.7-0.10.60.40.20.8-1.6-1.5
Patch foraging water rate 0 sec0.10.31.1-0.50.2-0.10.1-0.4-0.40.4-0.30.3-0.3-0.00.4-0.4-0.0-0.90.50.3-0.3-0.8-0.8-1.0-0.61.00.9
Patch foraging water rate 12 sec0.30.61.5-0.7-0.7-0.70.7-0.9-1.21.2-0.81.2-0.8-0.71.0-1.00.7-0.4-0.3-0.70.40.80.3-0.11.1-0.7-0.0
Patch foraging water rate 18 sec1.01.53.6-1.3-1.0-1.31.3-1.4-1.91.9-1.31.9-1.5-1.21.4-1.41.3-1.5-0.1-1.00.00.40.2-0.41.00.61.2
Patch foraging water rate 24 sec0.10.10.60.30.50.3-0.3-0.1-0.10.10.10.10.10.4-0.00.0-0.3-0.0-0.30.5-0.10.2-0.3-0.80.20.10.4
Patch foraging water rate 6 sec0.81.21.9-1.3-0.9-1.11.1-1.4-1.31.3-1.21.3-1.3-1.11.3-1.31.3-0.9-0.6-1.30.81.01.00.61.3-0.50.4
Seeking ratio, delayed vs. immediate footshock2.83.46.0-1.7-2.4-2.22.2-2.1-2.12.1-2.12.2-2.0-2.11.8-1.81.9-2.21.9-1.5-1.5-1.1-1.0-1.10.1-0.2-2.0
Distance traveled before self-admin0.70.94.9-0.2-0.4-0.50.5-0.2-0.30.3-0.20.1-0.2-0.40.3-0.30.0-0.82.20.3-1.9-1.8-1.8-1.7-1.2-0.3-0.4
Distance traveled after self-admin0.30.42.5-0.6-0.50.1-0.10.0-0.20.20.10.2-0.00.10.3-0.3-0.2-1.20.70.4-1.0-0.7-0.9-1.3-0.71.6-0.1
Extensor digitorum longus weight0.20.62.3-0.6-0.9-0.70.7-0.8-0.60.6-1.00.7-0.9-0.70.9-0.90.8-0.7-0.2-0.90.30.30.50.00.8-1.5-1.3
Bone: elastic displacement0.40.42.5-0.10.30.3-0.30.1-0.10.10.00.1-0.00.2-0.20.20.00.4-0.5-0.31.61.41.31.11.10.10.6
Bone: elastic work1.72.34.22.02.12.0-2.01.71.7-1.71.9-1.61.71.9-1.71.7-1.71.5-1.21.41.00.60.60.3-0.30.70.5
Bone: endosteal estimation1.02.27.21.11.51.3-1.31.11.3-1.31.1-1.40.71.0-0.80.8-0.41.4-2.7-0.12.62.42.52.01.7-0.61.1
Bone: endosteal perimeter1.73.79.91.91.92.0-1.91.81.7-1.71.8-1.81.71.6-1.71.7-1.12.1-3.10.22.82.72.72.51.4-0.50.4
Epididymis fat weight1.86.111.03.32.72.8-2.83.03.1-3.13.0-3.02.92.8-3.23.2-2.73.1-1.22.40.2-0.3-0.10.3-1.6-0.3-1.6
Delta time in closed arm before/after self-admin0.70.62.10.20.60.5-0.50.70.8-0.80.7-1.00.70.5-0.40.4-0.70.10.70.8-0.7-1.2-0.8-0.4-1.41.51.1
Delta time in open arm before/after self-admin0.80.83.0-0.90.1-0.30.3-0.5-0.60.6-0.40.6-0.2-0.40.6-0.60.60.3-1.5-0.91.21.71.31.21.4-1.2-0.8
Diff in mean of infusions in LGA sessions0.30.33.70.40.40.4-0.40.20.3-0.30.3-0.10.30.4-0.40.4-0.4-0.2-0.00.6-0.2-0.2-0.3-0.2-0.41.41.9
Delay discount exponential model param0.20.20.70.90.50.5-0.40.20.4-0.40.4-0.40.40.4-0.40.4-0.30.6-0.70.10.50.50.50.00.3-0.4-0.3
Extinction: sum of active levers before priming0.70.81.41.01.21.0-1.01.21.0-1.01.1-0.91.01.1-1.11.1-1.10.80.01.00.0-0.5-0.3-0.2-0.90.90.1
Active lever presses in extinction session 60.20.21.00.60.80.5-0.50.60.5-0.50.5-0.50.30.5-0.20.2-0.40.30.10.30.3-0.00.10.0-0.10.0-1.0
Bone: final force1.21.93.01.71.61.7-1.71.51.6-1.61.7-1.51.61.7-1.41.4-1.70.6-0.61.7-0.6-0.6-0.7-0.7-1.31.71.0
Bone: final moment1.32.13.61.81.71.8-1.81.61.6-1.61.7-1.61.71.8-1.51.5-1.80.6-0.81.8-0.5-0.5-0.7-0.7-1.31.91.1
Food consumed during 24 hour testing period1.31.82.61.51.41.5-1.51.51.6-1.61.6-1.61.51.5-1.41.4-1.60.9-0.41.6-0.5-0.7-0.6-0.5-1.31.60.5
Glucose0.20.33.00.3-0.1-0.10.2-0.00.1-0.1-0.2-0.0-0.1-0.20.2-0.20.1-0.60.8-0.1-0.8-0.6-0.6-0.8-0.2-0.5-1.7
Heart weight6.09.217.03.44.14.1-4.04.04.0-4.03.7-4.03.73.8-3.03.0-3.72.4-1.83.01.20.20.30.2-1.51.0-0.3
Delay discount hyperbolic model param0.10.20.70.80.30.3-0.30.10.2-0.20.2-0.20.30.3-0.30.3-0.10.5-0.7-0.10.60.70.60.10.5-0.3-0.2
Intermittent access intake day 1-15 change0.20.30.8-0.4-0.8-0.60.6-0.8-0.50.5-0.90.5-0.7-0.60.5-0.50.5-0.30.5-0.4-0.4-0.3-0.5-0.50.1-0.2-0.8
Intermittent access intake escalation0.20.41.1-0.7-1.0-0.80.8-1.0-0.60.6-1.00.7-0.8-0.70.7-0.70.7-0.40.3-0.6-0.2-0.1-0.3-0.30.3-0.2-0.4
Intermittent access intake escalation 20.50.61.4-0.4-1.2-0.90.9-0.9-0.80.8-1.00.9-0.9-0.90.8-0.80.8-0.30.5-0.8-0.30.1-0.2-0.20.6-0.6-0.8
Intermitt. access day 1 inactive lever presses0.51.94.91.21.10.9-0.91.01.1-1.10.9-1.21.01.0-0.50.5-1.3-0.21.81.6-2.0-2.2-2.2-2.2-2.10.9-1.3
Intermitt. access day 15 inactive lever presses1.02.08.0-0.10.60.5-0.50.60.8-0.80.5-0.80.50.6-0.10.1-1.0-1.32.31.5-2.6-2.7-2.8-2.7-2.30.60.2
Intermitt. access escalation Index0.30.43.8-0.8-0.4-0.30.3-0.5-0.40.4-0.50.3-0.5-0.30.7-0.70.2-1.10.6-0.1-0.4-0.3-0.4-0.50.10.62.0
Intermittent access day 1 total infusions0.71.12.40.61.01.1-1.11.10.9-0.91.2-1.01.21.1-0.90.9-1.30.40.11.4-0.9-1.0-0.9-0.8-1.60.81.6
Intermittent access day 15 total infusions0.10.10.5-0.7-0.4-0.10.1-0.2-0.10.1-0.10.2-0.1-0.10.3-0.3-0.0-0.20.10.1-0.4-0.4-0.4-0.3-0.4-0.20.4
Intermittent access terminal intake (last 3 days)0.00.00.2-0.2-0.5-0.10.1-0.10.0-0.0-0.00.10.0-0.10.1-0.10.00.3-0.1-0.1-0.1-0.1-0.00.1-0.2-0.30.3
Intermittent access total infusions0.20.20.80.30.20.5-0.50.50.4-0.40.6-0.40.60.5-0.40.4-0.60.40.00.6-0.5-0.6-0.5-0.3-0.90.30.7
Intermittent access day 1 locomotion0.40.61.90.50.70.4-0.40.50.3-0.30.5-0.30.50.4-0.30.3-0.7-0.31.00.7-1.2-1.4-1.3-1.2-1.30.2-0.6
Intermittent access day 15 total locomotion0.10.20.50.70.30.4-0.30.20.2-0.20.3-0.20.40.4-0.40.4-0.50.40.10.5-0.5-0.3-0.6-0.6-0.40.2-0.4
Intermittent access total locomotion0.30.40.90.80.30.4-0.40.40.4-0.40.6-0.40.60.5-0.60.6-0.60.40.50.7-0.9-0.8-0.8-0.8-0.90.3-0.8
Intermittent access standard deviation0.40.82.21.50.30.6-0.60.71.0-1.00.8-0.90.70.7-0.70.7-0.90.80.80.8-1.2-1.2-1.2-1.2-1.2-0.3-1.2
Left kidney weight8.539.665.46.98.18.1-8.17.97.9-7.97.5-8.07.57.9-7.17.1-7.45.9-4.66.62.11.00.80.9-2.52.91.7
Right kidney weight9.744.270.27.88.48.4-8.38.48.3-8.37.9-8.47.98.3-7.97.9-8.06.1-3.87.31.0-0.2-0.4-0.1-3.73.10.9
Cocaine induced anxiety0.60.93.11.80.20.7-0.70.50.5-0.50.5-0.50.90.9-1.41.4-1.00.90.31.2-1.0-0.8-1.1-0.9-1.01.6-0.2
Post-drug Anxiety0.10.10.50.4-0.7-0.30.3-0.5-0.50.5-0.50.40.0-0.1-0.40.40.10.2-0.10.0-0.20.1-0.2-0.10.10.70.4
Baseline Anxiety1.41.74.7-2.2-1.2-1.31.3-1.3-1.31.3-1.31.3-1.3-1.51.5-1.51.5-1.0-0.5-1.60.91.01.01.11.3-1.40.3
Tail length0.52.15.5-1.4-1.2-1.31.3-1.5-1.51.5-1.61.4-1.6-1.41.6-1.61.7-0.7-0.7-1.81.51.71.71.22.4-0.80.5
Length with tail0.20.92.70.90.90.9-0.90.70.9-0.90.7-0.90.70.8-1.01.0-0.61.1-1.60.41.31.21.21.00.80.41.2
Length without tail1.65.19.12.92.52.6-2.62.62.7-2.72.6-2.72.72.7-3.03.0-2.62.3-1.42.6-0.0-0.3-0.3-0.3-1.61.21.0
Times rat made contact with spout0.70.83.40.11.01.0-1.00.91.0-1.00.9-1.00.91.0-0.80.8-1.10.2-0.31.2-0.3-0.6-0.6-0.2-1.01.81.4
Lifetime Intake0.91.12.70.70.71.0-1.01.01.0-1.01.2-1.01.21.1-0.90.9-1.30.30.41.4-1.2-1.3-1.3-1.0-1.71.00.8
Liver weight, left1.22.06.20.71.11.1-1.11.11.2-1.21.3-1.31.41.0-1.21.2-0.82.1-2.50.22.02.01.92.31.0-1.30.5
Liver weight, right2.03.68.81.91.71.7-1.72.02.0-2.01.9-2.11.91.6-1.71.7-1.33.0-2.70.62.32.11.92.31.1-1.80.1
Locomotor activity1.52.34.42.11.61.9-1.91.71.6-1.61.8-1.61.71.8-1.91.9-1.51.9-1.51.11.41.11.10.90.20.40.2
Locomotor testing distance0.10.10.5-0.1-0.7-0.30.3-0.4-0.40.4-0.30.5-0.3-0.30.4-0.40.3-0.20.4-0.3-0.10.00.1-0.00.10.1-0.2
Locomotor testing rearing0.81.73.11.61.41.6-1.61.51.8-1.81.6-1.61.61.5-1.31.3-1.51.6-0.81.00.90.30.50.8-0.50.40.1
Locomotion in novel chamber1.11.43.7-1.5-0.3-0.20.2-0.4-0.20.2-0.30.2-0.2-0.51.0-1.00.70.2-1.8-1.31.91.91.91.81.4-1.9-1.6
Locomotion in novel chamber post-restriction0.61.01.9-1.1-1.2-1.31.3-1.1-1.11.1-1.11.1-1.1-1.31.0-1.01.3-0.40.4-1.40.30.50.50.61.0-0.6-1.0
Fecal boli incidents, locomotor time 10.10.20.7-0.5-0.3-0.50.5-0.4-0.40.4-0.50.4-0.6-0.50.4-0.40.5-0.90.3-0.40.10.1-0.1-0.10.60.80.4
Change in fecal boli incidents, locomotor task1.00.94.20.40.60.8-0.90.30.4-0.40.5-0.30.60.8-1.11.1-0.60.7-1.70.51.41.31.11.40.71.22.1
Time >=10cm from walls, locomotor time 10.10.10.40.60.20.3-0.30.30.1-0.10.4-0.10.40.3-0.40.4-0.30.2-0.10.30.00.0-0.0-0.1-0.20.50.1
Bouts of movement, locomotor time 10.30.31.50.70.10.2-0.20.40.1-0.10.4-0.10.50.4-0.90.9-0.41.00.10.5-0.5-1.0-0.30.1-1.20.1-0.1
Total resting periods, locomotor time 10.40.42.40.6-0.1-0.00.00.3-0.10.10.30.10.30.2-0.80.8-0.30.50.70.5-1.1-1.5-0.9-0.4-1.50.4-0.5
Rest time, locomotor task time 11.11.43.91.40.50.6-0.61.00.7-0.70.9-0.70.90.8-1.31.3-1.10.31.31.2-1.6-2.0-1.7-1.1-1.90.8-1.3
Distance moved, locomotor task time 10.50.72.40.31.00.7-0.70.71.0-1.00.7-1.00.60.60.1-0.1-0.41.2-1.50.11.21.11.10.90.4-0.80.9
Vertical activity count, locomotor time 10.10.10.7-0.3-0.00.1-0.1-0.20.2-0.2-0.1-0.2-0.20.00.6-0.60.10.2-0.7-0.10.50.80.50.00.6-0.70.3
Time >=10cm from walls, locomotor time 20.10.20.6-0.2-0.5-0.30.3-0.4-0.60.6-0.40.7-0.4-0.50.4-0.40.4-0.60.0-0.70.40.20.40.40.30.8-0.3
Bouts of movement, locomotor time 20.50.73.50.40.20.4-0.40.60.4-0.40.5-0.30.60.5-0.80.8-0.80.20.90.9-1.3-1.7-1.1-0.9-1.90.5-1.3
Total resting periods, locomotor time 20.50.83.70.40.10.4-0.40.60.3-0.30.4-0.20.50.5-0.70.7-0.7-0.01.00.9-1.4-1.9-1.3-1.1-1.90.7-1.1
Rest time, locomotor task time 20.20.20.9-0.1-0.4-0.30.3-0.1-0.20.2-0.10.3-0.2-0.2-0.20.20.0-0.61.00.2-0.8-0.9-0.7-0.5-0.50.4-0.6
Distance moved, locomotor task time 20.60.81.60.71.01.0-1.01.11.1-1.11.1-1.21.00.9-0.30.3-0.81.3-1.20.30.90.30.80.8-0.5-0.60.1
Vertical activity count, locomotor time 20.20.31.10.10.40.5-0.50.40.6-0.60.3-0.60.30.40.0-0.0-0.30.6-1.10.10.91.00.70.50.5-0.60.2
Light reinforcement 10.20.52.3-0.30.20.5-0.50.40.2-0.20.4-0.30.30.20.4-0.40.00.1-1.1-0.31.41.41.51.21.00.10.6
Light reinforcement 20.50.71.81.30.40.9-0.91.21.1-1.11.0-1.11.00.9-0.80.8-0.81.2-0.80.50.20.10.40.5-0.5-0.4-0.3
Bone: marrow area1.12.47.41.21.61.4-1.41.21.4-1.41.1-1.50.81.1-0.90.9-0.51.4-2.70.02.62.42.51.91.7-0.51.2
Bone: maximum diameter3.05.69.72.73.03.1-3.12.82.8-2.83.0-2.82.82.9-2.72.7-2.61.9-2.62.01.41.11.10.9-0.41.40.6
Bone: maximum force1.93.35.22.12.22.3-2.32.02.2-2.22.2-2.12.22.2-1.91.9-2.20.9-0.92.2-0.4-0.6-0.6-0.6-1.52.11.1
Bone: maximum moment2.13.76.02.22.32.5-2.42.22.3-2.32.3-2.22.22.4-2.02.0-2.31.0-1.12.3-0.2-0.5-0.5-0.5-1.52.21.1
Mean time between licks in bursts0.20.61.4-0.6-1.0-0.90.9-0.9-0.90.9-0.80.9-0.8-0.90.9-0.90.8-0.70.7-0.9-0.1-0.3-0.1-0.20.2-0.7-1.2
Mean num. licks in bursts1.21.83.01.61.71.6-1.61.61.7-1.71.5-1.51.61.6-1.71.7-1.61.5-0.61.40.2-0.1-0.10.2-0.90.10.1
Cd content in liver1.11.22.20.41.31.3-1.31.31.2-1.21.2-1.11.21.2-1.31.3-1.30.9-0.81.20.70.20.20.7-0.51.51.1
Co content in liver0.40.55.0-0.20.10.3-0.30.20.1-0.10.2-0.00.20.3-0.10.1-0.5-0.80.60.6-0.5-1.1-1.0-0.8-1.02.20.7
Cu content in liver4.75.610.2-2.8-2.7-2.72.7-3.2-2.92.9-3.02.9-2.9-2.83.0-3.02.8-2.91.0-2.4-0.60.2-0.0-0.71.5-0.40.4
Fe content in liver0.50.71.41.21.11.2-1.10.81.0-1.00.8-1.00.71.0-0.70.7-0.70.3-0.70.50.90.70.60.00.3-0.3-0.3
K content in liver0.90.81.8-1.3-0.6-1.11.0-1.1-1.11.1-1.20.9-1.3-1.01.2-1.21.1-1.20.3-0.8-0.3-0.1-0.1-0.40.50.00.7
Mg content in liver0.90.92.1-1.0-0.7-1.01.0-1.0-1.01.0-1.00.9-1.1-1.01.2-1.20.9-1.40.8-0.5-1.2-0.8-0.8-1.1-0.20.40.2
Mn content in liver0.20.20.8-0.50.70.0-0.10.10.4-0.40.1-0.5-0.00.00.1-0.10.10.3-0.9-0.20.70.70.60.80.5-0.40.4
Na content in liver1.71.83.1-1.3-1.4-1.61.6-1.7-1.71.7-1.71.6-1.5-1.61.6-1.61.6-1.51.0-1.5-0.30.0-0.0-0.30.8-1.1-0.4
Rb content in liver0.40.44.4-0.10.50.5-0.50.40.4-0.40.5-0.30.40.5-0.20.2-0.6-0.40.40.8-0.4-0.5-0.5-0.6-0.62.11.1
Se content in liver0.60.71.2-0.9-0.8-0.80.8-0.8-1.01.0-0.91.0-0.9-0.80.8-0.81.0-0.4-0.7-1.00.50.80.70.51.0-1.1-0.0
Sr content in liver1.81.62.5-1.6-1.6-1.61.6-1.4-1.41.4-1.51.5-1.2-1.51.6-1.61.3-1.31.3-1.1-0.7-0.8-0.7-0.5-0.0-0.7-0.5
Zn content in liver0.20.20.9-0.50.1-0.10.1-0.3-0.30.3-0.20.2-0.2-0.20.2-0.20.3-0.2-1.0-0.30.60.70.70.50.70.40.9
Bone: minimum diameter0.50.92.80.90.91.0-1.00.90.8-0.81.1-0.91.00.9-0.80.8-0.61.1-1.70.21.21.41.41.10.7-0.10.4
Time in familiar zone, hab. session 10.20.21.0-0.40.00.2-0.20.00.1-0.10.4-0.20.40.1-0.30.3-0.1-0.0-0.70.00.50.50.50.90.21.00.9
Time in novel zone, hab. session 10.60.61.51.21.20.8-0.80.90.8-0.80.5-0.70.40.7-0.50.5-0.61.0-0.60.21.00.50.50.10.2-1.2-1.0
Total zone transitions, hab. session 13.04.111.4-3.4-2.1-2.42.3-2.4-2.32.3-2.62.4-2.5-2.32.2-2.22.4-1.80.6-2.10.41.00.80.91.9-0.71.4
Total locomotion distance, hab. session 12.23.27.2-2.5-1.4-1.61.6-1.7-1.51.5-1.81.5-1.8-1.71.7-1.72.1-0.6-0.6-2.11.72.22.12.02.7-1.51.7
Locomotion velocity, hab. session 12.23.16.9-2.6-1.6-1.81.8-1.8-1.61.6-1.91.7-2.0-1.92.0-2.02.1-1.1-0.2-2.01.01.71.61.42.3-1.21.6
Time in familiar zone, hab. session 20.50.62.4-0.1-0.3-0.10.1-0.0-0.20.20.10.30.3-0.20.1-0.10.20.9-1.3-0.81.31.21.31.50.9-1.5-0.4
Time in novel zone, hab. session 20.30.31.60.10.60.3-0.30.20.3-0.30.2-0.4-0.10.4-0.20.2-0.4-0.50.70.8-0.5-0.6-0.8-1.1-0.51.30.7
Total zone transitions, hab. session 20.81.04.5-2.1-0.6-0.80.8-0.9-0.80.8-1.10.9-1.4-0.91.2-1.20.9-1.70.7-0.5-0.4-0.0-0.2-0.20.40.91.8
Total locomotion distance, hab. session 20.60.82.5-1.6-0.7-0.80.8-0.9-0.80.8-1.00.8-1.2-0.91.2-1.20.9-1.40.6-0.8-0.2-0.0-0.0-0.20.50.51.0
Locomotion velocity, hab. session 21.11.44.1-2.0-1.1-1.21.2-1.3-1.21.2-1.41.2-1.6-1.31.6-1.61.3-1.80.7-1.1-0.30.00.0-0.20.70.51.1
Novel to familiar place preference ratio2.02.24.31.82.11.7-1.71.31.4-1.41.5-1.51.41.6-1.81.8-1.31.8-2.00.92.01.51.31.10.60.50.9
Novelty place preference2.83.05.31.92.32.0-2.01.61.6-1.61.8-1.71.71.9-2.12.1-1.52.1-2.21.12.21.61.51.40.60.60.9
Time in novel zone, NPP test3.53.76.82.12.62.2-2.21.81.9-1.92.1-1.91.92.1-2.32.3-1.82.3-2.31.32.41.71.51.50.50.81.1
Total zone transitions, NPP test2.63.711.5-3.4-1.8-2.02.0-2.2-2.12.1-2.32.2-2.4-2.12.3-2.32.2-2.00.6-1.80.31.00.70.71.7-0.12.1
Total locomotion distance, NPP test1.31.85.0-2.2-1.2-1.41.4-1.5-1.41.4-1.71.4-1.8-1.41.5-1.51.5-1.40.6-1.20.10.50.40.21.20.21.8
Locomotion velocity, NPP test1.92.76.5-2.6-1.8-1.91.9-1.9-1.81.8-2.01.8-2.2-1.92.0-2.02.0-1.60.7-1.7-0.00.50.50.41.3-0.21.3
Intraocular pressure0.30.41.30.10.50.5-0.50.50.4-0.40.7-0.40.90.5-0.80.8-0.51.1-1.20.50.30.50.40.70.0-0.30.7
Delta distance traveled before/after self-admin1.11.25.2-0.10.71.2-1.20.70.8-0.80.8-0.60.81.0-0.50.5-0.70.4-2.30.51.51.71.41.10.61.81.3
Delta ambulatory time before/after self-admin1.31.66.2-0.01.01.4-1.40.90.9-0.90.9-0.90.91.2-0.60.6-0.90.4-2.50.61.71.71.41.20.62.22.3
Parametrial fat weight0.10.41.70.2-0.2-0.20.20.10.1-0.10.1-0.1-0.1-0.3-0.10.10.30.9-0.8-0.70.80.81.01.20.7-1.3-0.4
Pavlov. Cond. lever latency0.50.61.70.70.90.9-0.90.70.6-0.60.8-0.51.00.8-0.80.8-0.71.0-1.30.41.01.00.80.70.30.60.3
Pavlov. Cond. magazine entry latency0.70.93.3-1.0-1.0-0.90.9-0.7-0.60.6-0.70.5-0.7-0.80.8-0.80.5-1.21.8-0.2-1.4-1.6-1.4-1.1-0.90.3-0.2
Pavlov. Cond. change in total contacts1.31.33.8-1.3-1.0-0.90.9-0.8-0.80.8-0.80.6-1.0-0.91.1-1.10.6-1.91.9-0.1-1.7-1.7-1.7-1.5-1.01.10.1
Pavlov. Cond. index score0.70.93.7-0.6-0.7-0.70.7-0.4-0.30.3-0.50.2-0.6-0.50.5-0.50.3-1.11.90.2-1.7-1.8-1.6-1.3-1.20.2-0.4
Pavlov. Cond. latency score0.60.73.1-0.5-0.6-0.60.6-0.4-0.30.3-0.50.2-0.6-0.50.5-0.50.3-1.11.80.1-1.5-1.7-1.5-1.2-1.1-0.0-0.5
Pavlov. Cond. lever contacts1.41.74.1-1.2-1.5-1.51.5-1.2-1.11.1-1.41.0-1.5-1.41.4-1.41.2-1.62.0-0.8-1.5-1.4-1.2-1.1-0.4-0.7-0.8
Pavlov. Cond. magazine entry number0.91.13.81.01.11.0-1.00.60.6-0.60.7-0.50.70.8-0.80.8-0.51.3-2.00.01.81.81.61.21.2-0.30.2
Pavlov. Cond. intertrial magazine entries0.80.92.0-1.1-1.1-1.01.0-1.2-1.31.3-1.11.3-1.2-0.91.0-1.00.9-1.40.7-0.6-0.6-0.2-0.4-0.80.30.5-0.0
Pavlov. Cond. lever-magazine prob. diff.0.70.93.8-0.7-0.9-0.80.8-0.5-0.50.5-0.60.3-0.7-0.70.6-0.60.4-1.21.90.0-1.7-1.7-1.5-1.2-1.10.3-0.4
Pavlov. Cond. response bias1.11.34.3-1.0-1.3-1.21.1-0.8-0.80.8-0.90.7-1.0-1.01.0-1.00.7-1.42.1-0.3-1.9-1.8-1.6-1.3-1.00.1-0.3
Pavlov. Cond. lever latency0.60.82.60.50.70.8-0.80.90.9-0.90.9-0.71.10.7-1.01.0-0.81.6-0.60.31.30.80.91.50.1-0.20.3
Pavlov. Cond. magazine entry latency3.13.87.5-1.4-2.2-2.02.0-2.3-2.32.3-2.22.3-2.1-1.71.7-1.71.6-2.62.2-0.6-2.6-1.8-2.1-2.7-0.60.7-0.2
Pavlov. Cond. change in total contacts0.91.57.6-0.0-0.4-0.30.3-0.7-0.50.5-0.50.6-0.6-0.10.5-0.50.1-1.91.40.7-2.3-1.9-2.1-2.8-1.21.80.2
Pavlov. Cond. index score1.72.25.9-1.0-1.4-1.41.4-1.6-1.61.6-1.51.5-1.6-1.21.4-1.41.1-2.21.5-0.3-2.3-1.6-1.8-2.4-0.60.5-0.1
Pavlov. Cond. latency score2.22.96.6-1.3-1.7-1.71.7-1.9-1.91.9-1.81.8-1.8-1.51.6-1.61.3-2.51.8-0.5-2.4-1.7-1.9-2.6-0.60.7-0.0
Pavlov. Cond. lever contacts0.70.93.0-0.7-0.9-0.90.9-1.1-1.11.1-1.00.9-1.2-0.91.2-1.21.0-1.70.7-0.5-1.3-0.7-0.8-1.50.10.1-0.2
Pavlov. Cond. magazine entry number2.02.45.51.11.71.5-1.51.81.8-1.81.7-1.91.61.3-1.21.2-1.22.0-1.90.32.31.41.82.30.5-0.8-0.1
Pavlov. Cond. intertrial magazine entries2.23.36.41.42.22.0-2.02.22.4-2.42.4-2.52.32.0-1.81.8-2.21.3-0.12.1-0.3-1.2-1.0-0.3-2.00.90.2
Pavlov. Cond. lever-magazine prob. diff.1.82.45.5-1.0-1.6-1.51.5-1.8-1.71.7-1.61.7-1.7-1.31.4-1.41.3-2.21.5-0.5-2.2-1.5-1.7-2.3-0.40.3-0.3
Pavlov. Cond. response bias0.91.33.8-0.7-1.0-1.01.0-1.2-1.21.2-1.11.1-1.2-0.91.0-1.00.9-1.91.1-0.3-1.7-1.1-1.3-1.9-0.30.5-0.2
Time in closed arm before self-admin4.35.59.2-1.7-3.0-2.72.7-2.8-2.72.7-2.83.0-2.9-2.82.9-2.92.8-2.20.9-2.8-0.10.90.4-0.32.2-1.8-1.5
Time in closed arm after self-admin0.10.10.30.3-0.4-0.20.20.10.2-0.2-0.1-0.2-0.2-0.30.2-0.20.20.20.1-0.50.20.10.30.50.2-0.5-0.3
Time in open arm before self-admin0.10.10.30.00.1-0.10.10.00.0-0.00.1-0.10.0-0.0-0.50.50.10.50.1-0.00.2-0.20.30.5-0.30.20.5
Time in open arm after self-admin0.60.61.9-0.60.1-0.40.4-0.6-0.70.7-0.40.6-0.3-0.40.2-0.20.70.4-1.3-0.81.11.41.31.11.1-0.7-0.8
Bone: periosteal estimation1.22.67.11.71.91.9-1.91.71.7-1.71.8-1.81.41.6-1.41.4-1.21.5-2.70.72.01.91.91.40.90.20.9
Bone: periosteal perimeter3.05.29.82.62.52.7-2.72.52.4-2.42.8-2.42.62.4-2.52.5-2.02.5-3.11.22.32.12.22.00.50.20.3
Bone: post-yield work0.50.74.10.30.70.8-0.80.70.7-0.70.8-0.70.70.8-0.60.6-0.9-0.30.31.1-0.8-0.9-0.9-0.7-1.02.00.8
Progressive ratio test 1 active lever presses0.50.72.30.30.30.4-0.40.40.5-0.50.5-0.50.50.5-0.40.4-0.80.11.11.1-1.2-1.3-1.3-1.0-1.30.81.5
Progressive ratio test 1 breakpoint0.40.52.30.20.10.2-0.30.30.3-0.30.4-0.30.40.4-0.30.3-0.60.01.00.9-1.1-1.1-1.1-0.9-1.20.81.5
Progressive ratio test 1 inactive lever presses1.82.68.60.80.70.8-0.81.11.1-1.11.1-1.11.11.0-0.40.4-1.5-0.22.31.8-2.7-2.9-2.9-2.7-2.90.5-1.1
Progressive ratio test 2 active lever presses0.50.61.9-0.30.00.3-0.30.30.2-0.20.6-0.20.50.4-0.30.3-0.6-0.20.91.1-1.4-1.2-1.2-1.1-1.41.21.2
Progressive ratio test 2 breakpoint0.40.51.7-0.3-0.00.2-0.20.20.2-0.20.5-0.10.40.3-0.20.2-0.6-0.20.90.9-1.3-1.1-1.1-1.0-1.21.11.2
Progressive ratio test 2 inactive lever presses0.60.93.5-0.9-0.6-0.70.7-0.6-0.40.4-0.50.4-0.4-0.50.8-0.80.2-0.61.70.3-1.9-1.7-1.8-1.7-1.3-0.30.4
Incentive Sensitization - Responses0.10.20.8-0.8-0.2-0.10.1-0.0-0.20.20.20.20.2-0.10.2-0.2-0.1-0.30.50.4-0.8-0.5-0.6-0.6-0.60.70.9
Incentive Sensitization - Breakpoint0.20.20.8-0.6-0.10.0-0.00.1-0.00.00.40.10.30.10.0-0.0-0.2-0.30.50.5-0.9-0.7-0.7-0.7-0.80.90.7
Sum of active levers in priming session hrs 5-60.00.00.50.30.70.1-0.10.00.0-0.00.0-0.2-0.10.1-0.00.0-0.00.30.0-0.10.40.20.30.10.2-0.2-0.2
Progressive ratio0.20.31.4-0.0-0.3-0.40.4-0.4-0.10.1-0.40.0-0.4-0.30.1-0.10.3-0.31.0-0.1-0.6-0.7-0.6-0.9-0.2-0.7-1.2
Food seeking constrained by brief footshock1.21.53.11.30.61.5-1.51.41.3-1.31.5-1.31.61.5-1.81.8-1.60.9-0.81.4-0.1-0.1-0.20.0-0.91.20.5
Seeking ratio, punishment vs. effort0.50.82.20.90.61.1-1.11.10.8-0.81.1-0.71.11.0-1.01.0-1.10.6-0.71.0-0.0-0.1-0.10.3-0.71.50.9
Retroperitoneal fat weight3.012.822.24.74.14.3-4.34.44.4-4.44.4-4.34.34.3-4.54.5-4.14.3-2.23.50.90.40.30.8-1.41.00.2
Reaction time number correct0.91.72.7-1.3-1.6-1.41.4-1.5-1.51.5-1.41.5-1.3-1.41.3-1.31.5-0.3-0.3-1.60.91.21.41.41.3-1.10.4
Reaction time mean minus median0.10.42.00.40.80.4-0.40.70.6-0.60.4-0.50.20.3-0.10.1-0.30.6-0.3-0.11.00.60.60.60.5-1.4-0.9
Reaction time mean minus median AUC0.30.91.91.11.30.9-0.91.31.0-1.01.0-1.00.80.9-0.90.9-0.91.4-0.50.40.90.40.30.6-0.0-1.4-1.3
Reaction time num false alarms0.40.52.7-0.3-0.10.0-0.00.10.1-0.10.0-0.10.1-0.20.4-0.40.40.3-1.2-0.91.70.91.61.30.7-1.1-0.1
Reaction time num false alarms AUC0.40.63.0-0.6-0.2-0.10.1-0.0-0.10.1-0.10.0-0.1-0.30.7-0.70.50.2-1.3-0.91.71.01.71.40.7-1.10.4
Reaction time trials correct on left0.91.72.7-1.3-1.6-1.41.4-1.5-1.51.5-1.41.5-1.3-1.41.3-1.31.5-0.3-0.3-1.60.91.21.41.41.3-1.10.4
Reaction time trials on left1.01.82.9-1.3-1.6-1.51.4-1.5-1.61.6-1.41.6-1.3-1.51.4-1.41.6-0.3-0.4-1.71.01.31.51.41.4-1.10.4
Reaction time mean0.20.21.10.1-0.1-0.40.4-0.3-0.40.4-0.40.5-0.5-0.40.8-0.80.3-0.20.8-0.4-0.00.0-0.3-0.40.4-0.8-1.0
Reaction time mean AUC0.10.20.8-0.0-0.2-0.40.4-0.2-0.40.4-0.40.5-0.4-0.40.7-0.70.3-0.20.8-0.3-0.10.0-0.3-0.30.3-0.5-0.9
Median of all reaction times0.30.51.1-0.1-0.5-0.70.7-0.7-0.80.8-0.70.9-0.7-0.71.0-1.00.6-0.51.0-0.5-0.3-0.1-0.4-0.60.4-0.4-0.8
Reaction time omissions0.20.30.9-0.9-0.1-0.40.4-0.4-0.30.3-0.60.3-0.4-0.50.7-0.70.50.1-0.2-0.70.90.70.80.90.6-0.90.1
Reaction time false alarm rate0.20.30.70.20.50.6-0.60.80.7-0.70.6-0.80.60.5-0.10.1-0.30.4-0.70.00.8-0.00.60.4-0.3-0.6-0.2
Reaction time premature initiation rate0.40.62.5-0.1-0.7-0.20.2-0.3-0.40.4-0.30.4-0.4-0.10.3-0.30.2-1.41.00.3-1.2-0.9-1.0-1.6-0.41.60.4
Reaction time premature initiations0.30.51.4-0.4-1.2-0.60.6-0.8-0.90.9-0.70.9-0.7-0.60.6-0.60.6-1.20.7-0.3-0.8-0.4-0.5-0.90.01.10.4
Std. dev. reaction times0.30.51.50.60.90.7-0.70.90.8-0.80.6-0.70.50.6-0.30.3-0.60.8-0.40.20.90.70.50.50.4-1.2-1.0
Reaction time trials completed1.01.82.9-1.3-1.6-1.51.4-1.5-1.61.6-1.41.6-1.3-1.51.4-1.41.6-0.3-0.4-1.71.01.31.51.41.4-1.10.4
Reaction time trials AUC0.81.52.3-1.1-1.4-1.31.3-1.4-1.41.4-1.31.4-1.1-1.31.2-1.21.4-0.2-0.4-1.50.91.21.41.31.3-1.10.4
Run reversals in cocaine runway, females0.60.61.5-1.0-0.8-0.60.6-0.6-0.60.6-0.70.7-0.7-0.70.7-0.70.8-0.2-0.6-1.11.01.01.11.21.1-0.10.9
Run reversals in cocaine runway, males1.31.38.80.11.00.9-0.90.80.6-0.61.0-0.60.80.9-0.90.9-0.71.4-1.80.71.41.31.21.40.30.53.0
Latency to leave start box in cocaine runway0.10.21.40.70.10.2-0.20.40.3-0.30.3-0.30.30.3-0.40.4-0.30.70.20.3-0.1-0.3-0.2-0.2-0.2-0.2-1.2
Latency to leave start box in cocaine runway, F0.10.20.50.0-0.5-0.50.5-0.3-0.50.5-0.50.5-0.5-0.40.3-0.30.5-0.20.2-0.50.20.00.20.10.4-0.2-0.7
Latency to leave start box in cocaine runway, M0.80.81.71.10.70.8-0.81.01.0-1.01.0-1.01.00.9-1.01.0-1.01.3-0.01.0-0.4-0.5-0.6-0.4-0.8-0.2-1.1
Std. dev. time between licks in bursts0.91.33.5-1.4-1.1-1.11.1-1.5-1.21.2-1.31.1-1.5-1.11.2-1.21.1-1.91.2-0.7-1.0-0.6-0.6-1.20.21.00.0
Total sessions with >9 infusions4.85.89.62.32.62.7-2.72.82.7-2.72.9-2.72.72.7-2.42.4-3.00.80.53.1-1.5-2.0-1.9-1.5-2.82.71.0
Short access day 1 total inactive lever presses1.62.24.00.71.71.8-1.81.51.6-1.61.5-1.71.41.7-1.01.0-1.9-0.50.52.0-1.0-1.2-1.5-1.7-1.62.00.0
Short access day 10 total inactive lever presses0.40.91.51.20.61.1-1.11.11.2-1.21.0-1.21.11.1-1.01.0-1.11.0-0.60.90.3-0.10.00.1-0.7-0.4-1.1
Short access day 1 total infusions1.92.54.41.11.82.0-1.91.91.9-1.92.0-1.91.81.9-1.21.2-2.10.10.32.1-1.0-1.4-1.4-1.3-1.91.40.6
Short access day 10 total infusions1.21.62.71.41.01.3-1.31.51.4-1.41.6-1.41.41.3-1.11.1-1.50.60.51.5-1.1-1.4-1.2-1.0-1.61.2-0.1
Short access total infusions3.14.07.11.52.02.1-2.12.22.1-2.12.3-2.12.22.1-1.71.7-2.50.20.92.7-1.9-2.1-2.2-1.9-2.62.10.9
Short access day 1 locomotion0.81.01.51.21.01.0-1.01.21.2-1.21.0-1.20.91.0-0.70.7-1.10.00.71.1-0.9-1.2-1.0-1.1-1.20.5-0.2
Short access day 10 total locomotion0.71.211.40.40.1-0.20.20.20.2-0.20.3-0.2-0.0-0.20.1-0.1-0.1-0.61.90.1-1.6-2.1-1.3-1.4-1.5-0.6-3.4
Short access total locomotion1.51.84.21.41.21.1-1.11.41.3-1.31.4-1.31.21.1-1.01.0-1.40.11.31.3-1.5-2.0-1.5-1.4-1.90.7-1.6
One hour access (0.3 mA shock)0.20.31.7-0.2-1.0-0.50.5-0.3-0.40.4-0.20.5-0.2-0.40.2-0.20.2-0.00.5-0.2-1.0-0.5-0.6-0.5-0.3-0.2-1.3
Compulsive drug intake0.30.42.8-1.6-0.1-0.30.2-0.4-0.40.4-0.40.3-0.2-0.2-0.10.10.1-1.00.40.4-0.70.1-0.6-0.30.21.70.2
One hour access (shock baseline)0.10.21.30.7-0.9-0.40.4-0.2-0.10.1-0.10.3-0.1-0.40.3-0.30.20.60.2-0.5-0.5-0.3-0.2-0.3-0.3-1.1-1.0
Social response proportion0.30.32.31.20.60.4-0.40.20.5-0.50.2-0.40.00.4-0.30.3-0.4-0.20.20.3-0.4-0.4-0.9-1.1-0.00.0-1.5
Social responses0.20.31.2-0.5-0.4-0.10.1-0.2-0.10.1-0.10.2-0.4-0.20.2-0.20.4-0.3-0.9-0.50.91.00.80.71.10.40.4
Social time1.21.62.8-1.4-1.5-1.61.6-1.4-1.41.4-1.41.5-1.7-1.61.6-1.61.3-1.71.2-1.2-0.9-0.9-0.6-0.70.00.1-0.7
Soleus weight0.10.41.9-1.20.2-0.20.1-0.4-0.10.1-0.50.0-0.3-0.10.4-0.40.1-1.30.60.3-0.6-0.6-0.7-0.6-0.41.41.0
Bone: stiffness1.01.73.01.71.51.7-1.71.51.6-1.61.7-1.61.61.6-1.31.3-1.60.6-0.51.4-0.3-0.6-0.4-0.5-1.21.1-0.1
Tibialis anterior weight0.62.13.4-1.5-1.9-1.61.6-1.6-1.71.7-1.51.7-1.5-1.51.6-1.61.2-1.91.7-0.9-1.0-1.2-1.0-1.2-0.3-0.6-1.1
Time to tail flick, vehicle, before self-admin0.10.10.80.00.90.3-0.30.30.4-0.40.2-0.4-0.00.20.1-0.1-0.0-0.1-0.20.10.60.20.40.10.5-0.20.4
Time to tail flick, vehicle, after self-admin1.31.85.1-1.0-1.0-0.90.9-1.3-1.31.3-1.21.3-1.0-1.11.0-1.01.4-0.3-1.2-1.61.82.11.81.52.3-1.20.9
Time to tail flick, test, before self-admin0.50.61.70.50.40.7-0.71.00.8-0.80.9-0.80.90.7-1.11.1-0.61.3-0.90.50.50.40.50.9-0.4-0.10.2
Time to tail flick, test, after self-admin0.30.30.7-0.8-0.6-0.50.5-0.4-0.10.1-0.50.0-0.4-0.50.3-0.30.6-0.0-0.4-0.70.30.80.60.60.8-0.40.6
Delta time to tail flick, vehicle, before/after SA0.00.00.20.4-0.40.1-0.1-0.2-0.20.2-0.10.20.20.1-0.20.2-0.10.2-0.30.00.10.30.1-0.10.1-0.1-0.0
Delta time to tail flick, test, before/after SA1.71.73.5-1.7-1.3-1.51.5-1.7-1.31.3-1.71.2-1.6-1.51.9-1.91.5-1.60.4-1.4-0.00.60.2-0.31.4-0.80.0
Tibia length0.71.83.31.11.41.7-1.71.51.5-1.51.4-1.51.51.6-1.51.5-1.51.0-1.61.50.30.50.30.3-0.41.81.4
Ambulatory time before self-admin0.30.52.5-0.6-0.2-0.40.4-0.1-0.30.3-0.20.1-0.2-0.30.4-0.40.1-0.71.60.2-1.3-1.2-1.2-1.2-0.7-0.70.3
Ambulatory time after self-admin0.60.72.6-1.6-1.0-0.60.6-0.9-1.01.0-0.81.0-0.9-0.70.9-0.90.7-1.60.1-0.6-0.00.40.2-0.40.51.10.7
Bone: tissue strength0.20.20.70.40.20.5-0.50.2-0.00.00.40.10.40.5-0.50.5-0.30.4-0.80.30.40.70.50.30.30.50.8
Total heroin consumption0.50.63.00.30.80.6-0.60.70.5-0.50.6-0.40.50.7-0.30.3-0.8-0.10.51.0-0.5-0.9-0.8-0.5-1.11.41.7
Bone: trabecular number0.10.20.90.1-0.4-0.30.3-0.2-0.20.2-0.20.2-0.2-0.3-0.10.10.30.3-0.9-0.50.30.70.70.70.6-0.3-0.1
Bone: trabecular spacing1.11.42.41.11.31.4-1.41.41.3-1.31.2-1.31.51.4-1.51.5-1.50.60.11.5-0.3-0.7-0.7-0.3-1.31.2-0.4
Bone: trabecular thickness0.20.31.6-0.0-0.4-0.60.6-0.5-0.40.4-0.30.4-0.8-0.60.7-0.70.6-0.30.1-0.6-0.3-0.2-0.1-0.50.2-1.3-0.6
Bone: trabecular tissue density1.62.45.6-1.1-1.5-1.71.7-1.7-1.71.7-1.81.6-2.0-1.62.0-2.01.6-2.12.4-1.2-0.8-0.9-1.0-1.50.2-0.4-1.0
Water consumed over 24 hours0.50.62.30.20.90.9-0.90.80.9-0.90.8-0.90.70.9-0.50.5-0.90.2-0.61.0-0.0-0.2-0.2-0.1-0.51.51.5
Number of responses in last shaping day2.02.29.1-0.1-0.5-0.60.6-0.3-0.20.2-0.60.3-0.7-0.50.8-0.80.1-1.83.00.3-2.7-2.9-2.7-2.7-2.00.3-1.3