Hub : Genes

Xrcc6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Xrcc6 0.14 0.06 0.0e+00 0.22 0.22 0.22 0.22 1.7e-20 6.7e-20 7.4e-20 4.9e-20
2 NAcc mRNA stability Xrcc6 0.05 0.03 7.0e-07 0.05 0.05 0.04 0.06 1.9e-06 1.5e-06 3.9e-05 3.9e-07
3 PL mRNA stability Xrcc6 0.06 0.04 3.9e-08 0.06 0.05 0.05 0.06 2.6e-07 2.0e-06 3.8e-06 8.0e-07
4 Adipose mRNA stability Xrcc6 0.04 0.04 8.3e-03 0 0.01 0.01 0.01 9.6e-02 4.0e-02 3.4e-02 5.5e-02
5 BLA mRNA stability Xrcc6 0.08 0.05 1.1e-04 0.06 0.06 0.06 0.05 2.6e-04 4.2e-04 3.6e-04 1.5e-03
6 pVTA mRNA stability Xrcc6 0.05 0.04 9.8e-03 0.05 0.01 0.02 0.03 4.2e-03 1.5e-01 5.0e-02 2.4e-02
7 Adipose alternative TSS NM_139080.2 0.04 0.03 5.3e-04 0.02 0.02 0.01 0.02 2.8e-03 3.9e-03 3.2e-02 6.2e-03
8 Adipose alternative TSS XM_008765671.3 0.04 0.03 3.6e-04 0.02 0.02 0.01 0.02 2.1e-03 3.7e-03 2.0e-02 4.7e-03
9 Eye mRNA stability Xrcc6 0.32 0.21 2.5e-03 0.2 0.18 0.18 0.07 5.4e-04 9.1e-04 9.9e-04 3.5e-02
10 Adipose intron excision ratio chr7_113556255_113560166 0.06 0.03 1.2e-07 0.05 0.04 0.04 0.04 6.1e-06 2.2e-05 7.8e-05 4.1e-05
11 pVTA gene expression Xrcc6 0.07 0.05 3.1e-03 0.05 0.05 0.05 0.06 3.7e-03 2.2e-03 2.9e-03 1.1e-03
12 Adipose gene expression Xrcc6 0.55 0.13 0.0e+00 0.33 0.34 0.34 0.34 1.2e-37 4.9e-39 3.1e-39 1.5e-38
13 NAcc gene expression Xrcc6 0.16 0.07 4.0e-10 0.05 0.09 0.1 0.09 1.9e-06 8.6e-11 4.6e-11 1.7e-10
14 LHb mRNA stability Xrcc6 0.2 0.12 5.3e-03 0.04 0.04 0.03 0.05 4.1e-02 3.4e-02 6.9e-02 2.6e-02
15 PL gene expression Xrcc6 0.2 0.08 2.7e-14 0.12 0.14 0.13 0.13 1.1e-12 2.4e-15 4.4e-14 1.7e-14
16 BLA gene expression Xrcc6 0.14 0.07 2.5e-04 0.02 0.07 0.04 0.05 3.5e-02 1.3e-04 2.1e-03 1.1e-03
17 OFC gene expression Xrcc6 0.31 0.12 1.3e-04 0.22 0.12 0.19 0.21 5.0e-06 7.6e-04 3.3e-05 1.0e-05
18 Brain gene expression Xrcc6 0.09 0.05 2.7e-06 0.03 0.06 0.06 0.06 9.8e-04 1.4e-06 7.4e-06 4.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.20.40.80.9-0.80.8-0.50.90.80.7-0.70.30.3-0.6-0.60.3-0.3-0.3-0.5-0.5-0.4
Area under the delay curve0.20.21.10.3-0.30.3-1.10.40.40.5-0.50.50.4-0.3-0.20.7-0.3-0.4-0.10.4-0.2
BMI with tail1.44.48.9-2.52.6-2.60.6-2.4-2.4-2.22.2-2.3-2.32.32.40.53.0-1.1-0.62.2-1.1
BMI without tail0.10.11.0-0.10.2-0.21.0-0.0-0.3-0.00.00.00.0-0.20.1-0.30.90.0-0.10.4-0.2
Body weight1.14.87.6-2.82.7-2.71.9-2.6-2.6-2.52.5-2.7-2.62.62.7-0.82.0-0.00.50.70.2
Weight adjusted by age0.60.72.40.1-0.00.00.8-0.10.1-0.40.40.20.20.3-0.4-1.5-1.21.51.3-1.11.5
Bone surface0.30.52.10.6-0.50.60.60.70.60.2-0.20.20.2-0.1-0.6-0.9-1.11.30.6-1.41.0
Bone volume0.10.10.60.3-0.20.20.40.30.30.0-0.0-0.1-0.1-0.1-0.3-0.5-0.50.70.3-0.80.5
Breakpoint value in progressive ratio session0.20.20.9-0.0-0.10.1-0.50.50.10.1-0.10.00.0-0.10.00.70.5-0.8-1.00.6-0.9
Number of licking bursts0.30.40.80.8-0.70.7-0.70.90.70.7-0.70.80.8-0.2-0.70.1-0.70.30.1-0.40.3
Context. condit. distance diff. score4.95.910.6-3.13.0-3.02.1-3.1-2.8-3.33.3-2.7-2.72.12.5-1.61.41.01.6-0.01.1
Locomotion velocity, session 10.80.93.10.2-0.10.11.00.30.3-0.10.10.30.30.3-0.2-1.4-1.41.81.3-1.41.7
Locomotion distance, session 12.02.54.42.0-1.71.7-0.62.02.01.8-1.81.91.9-1.2-1.9-0.3-2.11.10.8-1.21.2
Locomotion velocity, session 20.30.30.8-0.20.7-0.70.8-0.6-0.4-0.60.6-0.6-0.60.70.3-0.60.30.90.60.20.6
Locomotion distance, session 21.92.75.22.1-1.81.8-2.32.02.01.9-1.91.91.9-1.0-1.51.7-0.7-0.9-1.40.6-1.0
Locomotion velocity, session 30.60.82.3-0.30.5-0.61.2-0.2-0.1-0.20.2-0.7-0.70.2-0.0-1.4-0.61.51.5-1.01.5
Locomotion distance, session 31.31.42.81.2-1.21.2-0.11.31.21.3-1.31.01.0-1.2-1.2-0.8-1.71.11.3-1.11.5
Stereotopy head waving bouts, day 30.60.71.4-0.81.0-1.00.9-1.0-1.2-1.11.1-1.1-1.11.10.9-0.60.30.50.3-0.20.3
Stereotopy head waving duration, day 32.83.35.7-1.92.2-2.22.4-2.2-2.1-2.22.2-2.1-2.11.91.7-1.60.61.20.9-0.40.8
Locomotion velocity, session 70.20.20.8-0.50.3-0.40.5-0.2-0.50.1-0.1-0.8-0.80.10.3-0.30.20.40.90.30.7
Locomotion distance, session 70.50.62.4-0.1-0.30.2-1.50.2-0.10.8-0.8-0.4-0.4-0.30.11.50.7-1.2-0.51.3-0.7
Stereotopy head waving bouts, day 73.33.811.2-1.41.6-1.53.3-1.6-1.6-2.02.0-1.4-1.41.31.2-2.9-0.82.52.2-2.02.3
Stereotopy head waving duration, day 72.53.011.1-1.21.4-1.33.3-1.4-1.5-1.71.7-1.3-1.30.81.0-2.7-0.62.22.0-1.72.0
Locomotion velocity, session 81.92.35.8-1.71.8-1.80.6-1.9-1.3-2.42.4-1.8-1.82.01.6-0.80.70.60.40.10.4
Locomotion distance, session 80.60.92.2-1.11.3-1.30.8-1.3-0.6-1.51.5-0.9-0.90.70.9-0.80.30.80.8-0.20.6
Degree of sensitization distance3.23.26.7-1.91.7-1.7-0.5-1.9-1.9-1.51.5-1.9-1.91.51.91.52.6-1.9-1.52.2-2.0
Degree of sensitization stereotypy2.62.98.6-1.01.1-1.12.9-1.2-1.2-1.51.5-1.0-1.00.90.9-2.7-0.92.32.2-2.02.3
Conditioned locomotion0.70.81.8-0.70.9-0.91.2-1.1-0.9-0.90.9-0.7-0.70.50.5-1.2-0.21.01.3-0.81.0
Cocaine response after cond. corrected0.10.10.3-0.30.2-0.20.6-0.1-0.0-0.00.0-0.3-0.40.2-0.0-0.40.10.50.5-0.20.5
Cocaine response after cond. not corrected0.10.10.6-0.20.3-0.30.7-0.20.2-0.10.1-0.1-0.2-0.0-0.3-0.5-0.00.80.6-0.30.5
Cocaine response before conditioning0.10.10.30.40.0-0.00.0-0.00.50.2-0.20.50.5-0.4-0.50.0-0.20.3-0.10.0-0.2
Saline control response0.81.13.70.20.3-0.31.3-0.50.1-0.50.50.10.1-0.4-0.4-1.9-1.31.91.3-1.91.3
Bone: connectivity density0.10.20.40.6-0.60.6-0.40.70.30.4-0.4-0.2-0.2-0.3-0.30.3-0.2-0.3-0.5-0.5-0.3
Bone: cortical apparent density0.40.61.20.9-0.90.9-1.00.90.61.1-1.10.80.8-0.6-0.70.6-0.7-0.3-0.4-0.3-0.2
Bone: cortical area1.11.73.1-1.81.8-1.81.3-1.6-1.4-1.51.5-1.4-1.41.71.6-0.51.00.30.30.40.2
Bone: cortical porosity0.40.41.0-0.70.9-0.91.0-0.9-0.6-0.60.6-0.6-0.60.40.4-0.60.30.40.3-0.40.1
Bone: cortical porosity0.91.01.9-1.11.3-1.31.4-1.3-1.0-1.11.1-1.3-1.30.90.9-0.80.50.50.4-0.30.2
Bone: cortical thickness0.71.23.1-0.80.7-0.7-1.2-0.6-0.7-0.20.2-0.7-0.71.01.11.61.5-1.6-1.41.8-1.4
Bone: cortical thickness0.91.13.0-0.70.7-0.7-1.1-0.8-0.8-0.60.6-0.4-0.41.21.11.21.5-1.5-1.11.7-1.2
Bone: cortical tissue density0.40.61.10.9-0.90.8-1.00.90.61.0-1.00.80.8-0.5-0.70.6-0.7-0.3-0.4-0.3-0.2
Condit. Reinf. active minus inactive responses0.30.41.40.2-0.10.1-1.10.40.40.5-0.50.40.40.1-0.21.20.4-0.7-0.80.9-0.8
Condit. Reinf. active-inactive response ratio0.20.20.5-0.70.6-0.70.3-0.5-0.5-0.50.5-0.5-0.50.60.5-0.10.30.20.10.40.1
Condit. Reinf. active responses1.11.42.41.3-0.90.9-1.61.21.41.4-1.41.41.4-0.9-1.11.6-0.0-0.8-1.20.9-1.1
Condit. Reinf. inactive responses2.12.54.42.1-1.61.6-1.51.61.91.8-1.81.91.9-1.9-1.71.3-0.7-0.7-1.10.4-1.1
Incentive salience index mean0.70.92.90.6-0.40.4-1.60.60.70.9-0.90.90.9-0.1-0.51.70.5-1.0-1.21.2-1.2
Condit. Reinf. lever presses0.71.02.11.1-0.70.7-1.30.70.91.1-1.11.31.3-0.6-0.81.50.2-0.7-0.91.0-0.9
Condit. Reinf. active minus inactive responses0.40.52.1-0.30.0-0.0-1.4-0.1-0.3-0.20.20.00.00.70.51.30.3-0.9-1.00.9-0.8
Condit. Reinf. active-inactive response ratio0.70.72.3-0.40.1-0.1-1.3-0.1-0.4-0.20.2-0.4-0.30.90.81.50.7-1.4-1.51.1-1.2
Condit. Reinf. active responses0.40.61.8-1.00.8-0.8-0.4-0.9-0.9-1.11.1-0.6-0.61.31.00.30.3-0.0-0.10.40.0
Condit. Reinf. inactive responses0.81.02.0-1.31.3-1.30.6-1.4-1.1-1.21.2-0.8-0.81.30.9-0.70.20.91.00.00.9
Condit. Reinf. lever presses0.30.31.10.5-0.60.6-1.00.20.50.1-0.10.60.6-0.2-0.50.9-0.4-0.5-1.00.0-0.8
Condit. Reinf. lever reinforcers received0.20.31.1-0.70.5-0.5-0.6-0.6-0.7-0.80.8-0.3-0.31.00.70.50.1-0.2-0.40.3-0.3
Conditioned reinforcement - actives0.50.51.4-0.90.8-0.8-0.3-0.6-1.2-0.50.5-0.7-0.81.10.7-0.4-0.20.50.90.10.8
Conditioned reinforcement - inactives0.50.52.6-0.20.2-0.2-1.60.1-0.10.3-0.30.60.60.40.31.20.4-1.0-1.10.9-1.0
Conditioned locomotion1.82.24.7-1.81.7-1.70.1-1.6-2.0-1.41.4-1.9-1.92.21.90.21.4-0.40.11.4-0.1
Patch foraging indifference point 0 sec0.30.61.70.7-0.70.7-0.60.60.80.6-0.61.01.0-0.2-0.50.8-0.3-0.7-1.3-0.0-1.1
Patch foraging indifference point AUC0.10.10.20.3-0.40.4-0.20.30.30.5-0.50.30.20.5-0.20.1-0.40.20.2-0.30.5
Delay disc. indifference point, 0s delay0.70.71.6-1.11.1-1.1-0.0-1.3-0.7-1.11.1-0.8-0.70.51.00.31.2-0.4-0.20.9-0.6
Delay disc. indifference point, 16s delay1.21.22.31.4-1.41.4-0.71.51.31.4-1.41.21.1-0.9-1.20.6-1.2-0.3-0.3-0.4-0.1
Delay disc. indifference point, 2s delay0.20.30.7-0.50.5-0.6-0.8-0.5-0.4-0.30.3-0.3-0.40.30.50.60.7-0.50.10.8-0.3
Delay disc. indifference point, 24s delay0.50.51.80.2-0.30.30.20.80.10.7-0.70.10.00.3-0.3-0.6-1.10.81.1-0.91.4
Delay disc. indifference point, 4s delay0.50.52.2-0.10.2-0.2-1.5-0.30.0-0.30.30.30.20.30.41.20.6-1.1-1.11.0-1.1
Delay disc. indifference point, 8s delay0.60.61.50.8-0.80.8-1.10.90.61.2-1.20.80.8-0.8-0.70.8-0.7-0.4-0.10.1-0.2
Indifference point function ln k0.71.02.2-1.11.2-1.20.7-1.1-1.2-1.51.5-1.2-1.20.61.0-0.60.70.10.20.3-0.0
Indifference point function log k0.71.02.2-1.11.2-1.20.7-1.1-1.2-1.51.5-1.2-1.20.61.0-0.60.70.10.20.3-0.0
Patch foraging total patch changes 0 sec0.40.71.80.9-0.90.9-0.70.80.90.7-0.71.11.1-0.4-0.60.7-0.5-0.7-1.3-0.2-1.1
Patch foraging total patch changes 12 sec0.10.10.60.00.1-0.1-0.2-0.10.00.0-0.00.10.00.70.10.60.2-0.4-0.80.1-0.6
Patch foraging total patch changes 18 sec0.30.31.40.2-0.30.4-0.70.20.00.1-0.10.60.60.30.11.00.1-0.9-1.20.3-1.0
Patch foraging total patch changes 24 sec0.20.20.50.6-0.60.60.40.50.60.7-0.70.60.6-0.2-0.40.2-0.4-0.0-0.3-0.3-0.1
Patch foraging total patch changes 6 sec0.20.31.20.5-0.30.3-0.70.30.80.1-0.10.90.90.7-0.40.6-0.1-0.3-1.10.3-0.7
Patch foraging time to switch 0 sec0.10.10.7-0.0-0.20.20.60.10.20.4-0.4-0.0-0.0-0.8-0.3-0.0-0.00.10.1-0.2-0.1
Patch foraging water rate 0 sec0.20.21.00.5-0.20.3-0.70.40.4-0.20.20.70.70.3-0.20.30.1-0.4-1.00.3-0.7
Patch foraging water rate 12 sec0.30.51.00.9-0.80.80.71.00.80.6-0.60.80.8-0.8-0.6-0.4-0.60.3-0.2-0.60.1
Patch foraging water rate 18 sec1.01.33.71.5-1.31.3-0.21.81.91.0-1.01.51.5-0.6-1.4-0.2-1.10.4-0.4-0.90.1
Patch foraging water rate 24 sec0.10.10.80.10.00.00.00.1-0.1-0.30.30.10.10.20.30.20.5-0.4-0.90.3-0.6
Patch foraging water rate 6 sec1.01.53.01.5-1.41.40.51.31.20.9-0.91.31.3-1.1-1.3-1.0-1.71.20.6-1.61.0
Seeking ratio, delayed vs. immediate footshock2.63.05.52.0-2.12.0-1.32.01.62.3-2.31.92.0-1.9-1.71.5-0.9-1.2-1.3-0.3-1.1
Distance traveled before self-admin1.21.24.1-0.30.2-0.3-1.8-0.3-0.2-0.10.10.60.60.10.52.01.3-2.0-1.61.6-1.9
Distance traveled after self-admin0.40.41.6-0.30.4-0.4-0.5-0.2-0.3-0.10.10.20.21.20.50.70.6-0.9-1.10.6-1.0
Extensor digitorum longus weight0.20.71.50.9-1.01.00.30.71.20.9-0.91.01.0-1.0-1.1-0.4-0.70.4-0.2-0.7-0.1
Bone: elastic displacement0.60.72.60.10.0-0.01.50.10.0-0.40.4-0.2-0.20.2-0.1-1.6-0.71.51.1-1.01.3
Bone: elastic work1.62.14.0-1.61.6-1.61.7-1.5-1.5-2.02.0-1.8-1.81.71.6-0.91.20.40.20.40.2
Bone: endosteal estimation1.53.210.2-0.91.3-1.33.2-1.3-0.9-1.81.8-1.0-1.01.00.5-2.9-0.82.92.2-1.92.3
Bone: endosteal perimeter2.34.815.6-1.91.9-1.94.0-1.9-1.6-2.12.1-1.7-1.71.31.2-3.2-0.42.92.8-1.82.6
Epididymis fat weight2.66.010.1-3.22.9-2.92.8-3.0-2.9-2.72.7-2.9-2.91.92.6-1.71.61.12.10.41.5
Delta time in closed arm before/after self-admin1.51.53.2-1.51.6-1.6-0.5-1.7-1.3-1.41.4-1.1-1.11.81.40.51.2-0.6-0.01.3-0.4
Delta time in open arm before/after self-admin0.50.51.60.5-0.60.60.80.80.10.1-0.10.20.2-1.3-0.6-0.8-0.80.80.7-1.00.8
Diff in mean of infusions in LGA sessions0.40.43.30.5-0.60.6-1.80.70.80.5-0.50.30.3-0.0-0.40.9-0.0-0.7-0.50.2-0.4
Delay discount exponential model param0.20.21.2-0.40.4-0.41.1-0.4-0.4-0.60.6-0.5-0.50.30.3-0.60.40.30.0-0.20.1
Extinction: sum of active levers before priming0.10.10.6-0.20.1-0.1-0.80.0-0.0-0.10.1-0.3-0.30.20.10.50.3-0.4-0.30.5-0.4
Active lever presses in extinction session 60.30.30.6-0.40.4-0.4-0.7-0.4-0.3-0.70.7-0.8-0.80.20.20.30.6-0.3-0.40.7-0.5
Bone: final force1.42.34.8-1.81.7-1.8-0.5-1.6-1.6-1.51.5-1.8-1.82.21.90.81.6-1.2-0.91.3-1.0
Bone: final moment1.52.55.2-1.81.8-1.8-0.3-1.6-1.7-1.71.7-1.8-1.82.32.00.71.6-1.0-0.91.2-0.9
Food consumed during 24 hour testing period1.31.62.9-1.51.6-1.6-0.5-1.3-1.4-1.21.2-1.6-1.61.71.50.41.5-0.7-0.41.2-0.6
Glucose0.30.50.80.7-0.70.7-0.30.50.80.6-0.60.90.9-0.9-0.70.70.2-0.6-0.90.2-0.9
Heart weight2.33.25.1-2.02.3-2.20.6-2.2-2.1-2.22.2-1.4-1.32.12.20.42.0-1.2-1.11.8-1.4
Delay discount hyperbolic model param0.10.11.2-0.10.2-0.11.1-0.2-0.2-0.40.4-0.3-0.30.10.1-0.70.20.40.1-0.40.2
Intermittent access intake day 1-15 change0.30.30.90.8-0.90.9-0.10.50.40.9-0.90.40.4-0.6-0.50.3-0.5-0.3-0.3-0.0-0.2
Intermittent access intake escalation0.40.41.00.9-1.01.0-0.10.60.50.9-0.90.60.7-0.7-0.60.3-0.6-0.3-0.4-0.1-0.3
Intermittent access intake escalation 20.20.20.60.5-0.70.70.20.30.40.5-0.50.40.5-0.6-0.4-0.2-0.80.2-0.0-0.30.0
Intermitt. access day 1 inactive lever presses1.01.12.3-0.70.7-0.6-1.0-0.8-0.7-1.11.1-0.0-0.00.81.01.11.5-1.3-1.51.4-1.5
Intermitt. access day 15 inactive lever presses2.02.25.1-1.01.0-1.0-2.0-1.1-1.1-1.01.0-0.4-0.41.21.42.02.0-2.0-1.92.2-1.9
Intermitt. access escalation Index0.20.20.60.2-0.20.2-0.70.00.00.2-0.20.40.40.20.20.60.2-0.8-0.80.4-0.7
Intermittent access day 1 total infusions0.91.02.3-1.31.4-1.4-0.4-0.9-1.5-0.90.9-0.6-0.71.51.40.41.2-0.5-0.21.0-0.3
Intermittent access day 15 total infusions0.20.20.7-0.00.0-0.0-0.70.0-0.50.3-0.30.10.10.40.50.70.2-0.9-0.70.6-0.6
Intermittent access terminal intake (last 3 days)0.10.10.3-0.20.3-0.3-0.0-0.2-0.50.1-0.1-0.2-0.20.40.40.1-0.0-0.20.10.20.0
Intermittent access total infusions0.30.40.9-0.70.7-0.7-0.5-0.4-1.0-0.30.3-0.4-0.50.90.90.50.6-0.7-0.30.7-0.4
Intermittent access day 1 locomotion0.60.61.1-0.80.8-0.9-0.8-0.5-1.1-0.70.7-0.6-0.60.91.00.51.1-0.7-0.41.0-0.6
Intermittent access day 15 total locomotion0.10.10.4-0.40.3-0.3-0.2-0.1-0.70.0-0.0-0.5-0.60.50.60.10.3-0.3-0.10.2-0.1
Intermittent access total locomotion0.60.71.1-0.80.8-0.8-0.7-0.5-1.0-0.40.4-0.7-0.81.11.10.71.1-0.9-0.61.0-0.7
Intermittent access standard deviation0.70.81.6-0.90.8-0.80.3-1.0-1.1-0.50.5-0.6-0.51.01.20.81.1-1.1-0.81.3-1.0
Left kidney weight9.326.143.8-6.66.6-6.63.0-6.3-6.0-6.26.2-6.0-5.96.66.1-1.73.90.51.22.10.8
Right kidney weight10.328.949.0-6.97.0-7.02.8-6.6-6.3-6.76.7-6.1-6.07.06.5-1.54.50.21.02.70.4
Cocaine induced anxiety1.11.32.7-1.00.9-0.9-0.7-0.7-0.8-0.40.4-1.2-1.20.81.11.31.6-1.6-1.41.6-1.4
Post-drug Anxiety0.30.30.8-0.50.3-0.3-0.4-0.3-0.3-0.10.1-0.6-0.50.70.60.60.8-0.8-0.90.6-0.8
Baseline Anxiety1.11.22.21.3-1.21.2-0.11.01.20.9-0.91.11.1-0.9-1.4-0.8-1.51.10.8-1.40.9
Tail length0.30.81.40.9-0.90.90.80.90.80.8-0.81.01.0-1.2-0.9-1.0-1.00.80.6-1.10.7
Length with tail0.31.02.1-0.90.8-0.81.4-1.0-0.8-1.11.1-1.0-0.91.10.9-1.3-0.30.91.0-0.91.1
Length without tail0.92.05.2-1.81.7-1.70.3-1.7-1.4-1.61.6-2.0-2.02.31.7-0.20.5-0.00.30.10.3
Times rat made contact with spout0.70.82.2-0.91.0-1.0-0.8-0.9-0.8-1.01.0-0.9-0.91.51.00.41.0-0.5-0.31.1-0.4
Lifetime Intake1.21.32.4-1.21.2-1.3-0.8-0.9-1.5-0.80.8-0.8-0.81.61.51.11.3-1.4-0.91.5-1.0
Liver weight, left1.01.65.3-1.11.0-1.02.3-1.1-1.1-0.90.9-1.0-0.90.50.8-1.9-0.31.61.7-1.41.6
Liver weight, right2.33.78.5-2.01.9-1.92.9-2.1-1.9-1.81.8-2.3-2.31.11.4-2.30.11.82.4-1.12.0
Locomotor activity1.42.24.2-1.71.8-1.81.4-1.6-1.8-1.61.6-2.1-2.11.61.5-1.30.80.90.9-0.20.9
Locomotor testing distance0.00.10.20.1-0.00.0-0.00.3-0.10.5-0.5-0.1-0.1-0.0-0.1-0.1-0.40.10.1-0.40.2
Locomotor testing rearing1.11.73.6-1.61.8-1.81.0-1.6-1.9-1.31.3-1.6-1.51.31.4-0.80.70.40.90.40.6
Locomotion in novel chamber1.72.15.60.7-0.80.82.30.70.20.6-0.60.91.0-1.1-1.1-2.3-2.12.42.0-1.42.0
Locomotion in novel chamber post-restriction0.60.71.51.1-1.01.00.21.01.01.2-1.20.90.9-0.9-1.2-0.0-0.90.20.3-0.60.3
Fecal boli incidents, locomotor time 10.20.30.80.7-0.70.7-0.90.70.60.4-0.40.50.5-0.2-0.80.3-0.2-0.1-0.3-0.1-0.2
Change in fecal boli incidents, locomotor task0.90.82.6-0.50.4-0.41.3-0.4-0.8-0.30.3-0.8-0.80.60.7-1.3-0.81.11.4-0.91.6
Time >=10cm from walls, locomotor time 10.00.00.1-0.40.3-0.30.2-0.1-0.0-0.10.1-0.3-0.30.40.20.00.2-0.1-0.10.0-0.1
Bouts of movement, locomotor time 10.20.31.0-0.50.4-0.4-0.50.1-0.40.1-0.1-1.0-1.00.40.50.50.6-0.40.20.60.1
Total resting periods, locomotor time 10.40.41.3-0.30.2-0.3-1.00.3-0.20.3-0.3-0.7-0.80.30.41.10.8-1.0-0.41.0-0.5
Rest time, locomotor task time 11.11.34.1-0.80.8-0.8-1.1-0.4-0.6-0.10.1-0.9-0.90.70.81.71.7-1.7-1.02.0-1.4
Distance moved, locomotor task time 10.60.61.4-0.60.7-0.71.0-1.1-0.8-1.11.1-0.3-0.30.40.5-1.2-0.21.10.9-0.60.8
Vertical activity count, locomotor time 10.10.10.40.2-0.20.20.1-0.2-0.1-0.00.00.30.4-0.4-0.0-0.4-0.50.3-0.0-0.60.1
Time >=10cm from walls, locomotor time 20.10.10.40.2-0.30.30.50.50.60.4-0.40.40.4-0.0-0.3-0.2-0.40.30.2-0.50.2
Bouts of movement, locomotor time 20.91.02.1-0.50.5-0.6-1.3-0.6-0.9-0.40.4-0.9-0.90.71.01.41.4-1.4-0.91.4-1.2
Total resting periods, locomotor time 20.91.02.4-0.40.4-0.4-1.6-0.6-0.8-0.40.4-0.8-0.80.70.91.51.3-1.5-1.01.5-1.2
Rest time, locomotor task time 20.20.21.30.2-0.20.1-1.10.30.30.4-0.40.10.1-0.1-0.20.70.1-0.5-0.40.5-0.4
Distance moved, locomotor task time 20.60.71.2-1.01.1-1.11.1-1.1-1.0-1.01.0-0.6-0.50.50.9-0.80.60.70.80.00.5
Vertical activity count, locomotor time 20.30.31.4-0.50.4-0.41.2-0.7-0.4-0.50.5-0.5-0.40.40.6-0.70.20.50.5-0.40.4
Light reinforcement 10.51.04.4-0.40.3-0.32.1-0.3-0.4-0.20.20.20.20.3-0.1-1.6-1.11.61.2-1.51.3
Light reinforcement 20.50.61.6-1.01.1-1.11.3-1.2-0.8-0.30.3-0.9-0.90.50.8-0.50.30.40.7-0.10.4
Bone: marrow area1.63.410.5-1.01.4-1.43.2-1.4-0.9-1.91.9-1.1-1.11.10.6-3.0-0.82.92.2-1.92.3
Bone: maximum diameter3.15.79.3-2.93.0-3.02.8-2.9-2.7-3.03.0-2.4-2.42.92.6-1.71.21.21.2-0.01.0
Bone: maximum force2.34.07.7-2.52.5-2.50.3-2.3-2.2-2.32.3-2.3-2.32.82.40.32.1-0.7-0.61.5-0.7
Bone: maximum moment2.54.38.3-2.52.6-2.60.4-2.4-2.4-2.52.5-2.4-2.42.92.50.22.2-0.6-0.51.5-0.6
Mean time between licks in bursts0.50.71.40.8-0.90.9-0.70.91.01.0-1.01.11.1-1.2-0.80.2-0.6-0.3-0.3-0.4-0.3
Mean num. licks in bursts1.31.62.7-1.61.5-1.50.5-1.7-1.5-1.61.6-1.6-1.61.31.5-0.21.2-0.20.20.9-0.1
Cd content in liver0.91.02.0-0.91.3-1.31.2-1.2-0.9-1.41.4-0.7-0.71.10.7-1.20.30.71.00.20.7
Co content in liver0.40.41.2-0.80.9-0.9-0.5-0.7-0.5-0.70.7-0.6-0.61.10.60.10.6-0.4-0.40.5-0.5
Cu content in liver3.13.76.42.3-2.52.5-1.02.42.42.1-2.12.52.5-2.3-2.20.8-1.7-0.2-0.8-1.0-0.5
Fe content in liver0.20.31.40.10.3-0.31.2-0.1-0.0-0.20.20.10.1-0.0-0.2-1.0-0.30.90.3-1.00.4
K content in liver0.60.61.40.7-0.80.8-1.10.80.90.4-0.40.90.9-0.2-0.61.10.0-0.7-1.20.6-0.9
Mg content in liver1.21.23.30.8-1.01.0-1.41.11.20.8-0.81.21.2-0.4-0.71.8-0.0-1.3-1.80.6-1.5
Mn content in liver0.30.41.0-0.50.6-0.60.7-0.6-0.3-0.90.9-0.4-0.40.40.2-0.7-0.30.81.0-0.40.9
Na content in liver2.12.34.31.7-2.02.0-1.12.11.91.6-1.61.81.8-1.7-1.80.8-1.0-0.4-0.7-0.4-0.5
Rb content in liver0.10.10.3-0.00.2-0.2-0.4-0.1-0.1-0.10.10.40.40.30.10.5-0.0-0.3-0.60.1-0.4
Se content in liver0.60.71.40.9-0.90.90.11.00.90.9-0.90.80.8-1.1-1.2-0.3-0.90.70.4-0.90.6
Sr content in liver0.60.61.20.9-0.90.9-0.80.90.81.1-1.10.70.7-1.0-0.90.3-0.3-0.20.10.3-0.0
Zn content in liver1.21.42.51.4-1.41.40.11.41.40.9-0.91.61.6-1.2-1.4-0.4-1.40.70.2-1.40.4
Bone: minimum diameter0.71.34.8-1.21.1-1.12.2-1.1-0.9-1.01.0-0.7-0.70.80.8-1.4-0.11.51.3-0.71.3
Time in familiar zone, hab. session 10.10.10.7-0.40.0-0.00.3-0.1-0.1-0.00.00.10.10.40.2-0.4-0.20.50.80.10.8
Time in novel zone, hab. session 10.60.61.5-0.40.8-0.81.2-0.8-0.7-1.21.2-0.8-0.80.30.4-1.00.30.50.1-0.50.0
Total zone transitions, hab. session 12.94.06.32.5-2.32.3-1.02.42.42.2-2.22.52.5-1.8-2.3-0.3-2.51.20.7-1.61.2
Total locomotion distance, hab. session 12.33.26.41.8-1.61.60.81.51.81.3-1.31.71.7-1.6-1.9-1.6-2.52.51.8-2.22.2
Locomotion velocity, hab. session 12.13.05.42.0-1.71.70.21.72.11.5-1.52.02.0-1.7-2.0-1.0-2.31.91.3-1.71.7
Time in familiar zone, hab. session 20.70.82.7-0.3-0.10.11.7-0.00.30.3-0.30.30.3-0.7-0.2-1.4-0.71.31.7-0.91.5
Time in novel zone, hab. session 20.40.41.50.10.3-0.2-1.1-0.2-0.3-0.80.8-0.3-0.30.80.30.70.5-0.8-1.20.5-1.0
Total zone transitions, hab. session 20.60.82.21.3-0.90.9-1.30.81.10.6-0.61.51.5-0.1-0.90.4-1.00.2-0.3-0.3-0.0
Total locomotion distance, hab. session 20.40.61.41.2-1.01.0-0.70.81.00.6-0.61.21.2-0.5-0.90.4-0.60.2-0.30.0-0.1
Locomotion velocity, hab. session 20.91.22.91.6-1.41.4-0.91.11.41.1-1.11.71.7-0.9-1.30.5-0.80.3-0.3-0.1-0.1
Novel to familiar place preference ratio2.32.44.6-1.41.4-1.42.0-1.3-1.6-2.22.2-1.8-1.81.31.2-2.0-0.01.21.1-1.11.2
Novelty place preference3.13.15.7-1.71.7-1.62.2-1.6-1.9-2.42.4-2.1-2.11.51.5-2.20.11.41.4-1.11.5
Time in novel zone, NPP test3.83.97.3-2.02.0-1.92.4-1.8-2.1-2.72.7-2.3-2.31.71.7-2.30.21.41.5-1.11.5
Total zone transitions, NPP test2.23.15.72.4-2.02.0-1.02.02.31.6-1.62.42.4-1.4-2.0-0.2-2.31.10.5-1.41.0
Total locomotion distance, NPP test1.01.32.91.7-1.41.4-0.81.41.51.1-1.11.41.4-1.0-1.40.1-1.20.60.1-0.60.4
Locomotion velocity, NPP test1.62.34.42.1-1.81.8-0.81.82.01.7-1.71.91.9-1.5-1.80.2-1.50.60.2-0.80.5
Intraocular pressure0.30.40.8-0.90.6-0.60.4-0.5-0.8-0.60.6-0.8-0.80.40.7-0.50.30.40.9-0.00.8
Delta distance traveled before/after self-admin1.01.03.4-0.40.6-0.51.7-0.5-0.5-0.60.6-0.7-0.71.40.4-1.8-0.71.71.1-1.11.5
Delta ambulatory time before/after self-admin1.01.13.7-0.40.6-0.51.3-0.6-0.4-0.80.8-0.6-0.61.60.4-1.9-0.71.81.0-1.11.4
Parametrial fat weight0.20.50.8-0.70.7-0.7-0.7-0.7-0.6-0.50.5-0.7-0.70.50.50.60.9-0.8-0.40.9-0.7
Pavlov. Cond. lever latency0.91.12.0-1.30.9-0.91.4-1.1-1.0-1.41.4-1.0-1.00.81.0-1.4-0.00.60.9-0.70.9
Pavlov. Cond. magazine entry latency1.11.44.40.8-0.80.7-2.11.00.81.4-1.41.01.0-0.3-0.71.90.5-1.4-1.31.4-1.3
Pavlov. Cond. change in total contacts1.61.75.61.0-0.80.7-2.41.00.81.2-1.21.01.0-0.1-0.62.20.6-1.5-1.61.8-1.6
Pavlov. Cond. index score1.01.34.70.5-0.30.2-2.20.50.31.0-1.00.50.50.1-0.32.11.0-1.6-1.51.8-1.6
Pavlov. Cond. latency score0.91.13.80.6-0.30.2-2.00.50.30.9-0.90.50.50.0-0.31.90.9-1.4-1.41.6-1.5
Pavlov. Cond. lever contacts1.31.53.61.3-0.90.9-1.91.11.01.5-1.51.21.2-0.9-1.01.80.3-1.1-1.21.3-1.3
Pavlov. Cond. magazine entry number0.91.14.2-0.60.5-0.52.1-0.7-0.5-1.11.1-0.8-0.80.10.5-1.8-0.71.31.1-1.51.2
Pavlov. Cond. intertrial magazine entries0.70.91.81.3-1.21.3-0.91.31.01.0-1.01.01.0-0.8-0.90.6-0.8-0.4-0.9-0.3-0.5
Pavlov. Cond. lever-magazine prob. diff.1.11.34.70.7-0.40.4-2.20.70.51.2-1.20.70.7-0.1-0.42.10.8-1.5-1.31.7-1.4
Pavlov. Cond. response bias1.31.65.20.9-0.60.6-2.30.80.71.4-1.40.90.9-0.3-0.62.20.7-1.6-1.41.6-1.5
Pavlov. Cond. lever latency0.71.01.9-1.31.2-1.20.8-1.0-1.2-0.50.5-1.3-1.40.71.1-0.80.60.31.40.30.9
Pavlov. Cond. magazine entry latency3.74.28.02.2-2.32.3-2.82.32.02.0-2.02.12.1-1.6-1.52.3-0.7-2.0-2.70.5-2.2
Pavlov. Cond. change in total contacts1.31.78.00.8-0.90.9-2.20.70.70.1-0.10.80.90.2-0.22.00.2-1.9-2.80.9-2.3
Pavlov. Cond. index score2.22.95.81.9-1.91.9-2.41.81.71.3-1.31.81.8-1.2-1.41.9-0.7-1.5-2.40.3-1.9
Pavlov. Cond. latency score2.83.57.12.0-2.12.1-2.71.91.91.5-1.52.02.0-1.3-1.52.2-0.6-1.7-2.70.5-2.1
Pavlov. Cond. lever contacts0.71.02.71.2-1.11.1-1.10.91.20.5-0.51.21.2-0.7-1.01.1-0.5-0.6-1.7-0.1-1.3
Pavlov. Cond. magazine entry number2.12.66.2-1.61.8-1.82.5-1.8-1.3-1.31.3-1.5-1.51.10.9-2.10.41.82.4-0.61.9
Pavlov. Cond. intertrial magazine entries2.83.66.4-2.32.5-2.5-0.2-2.5-2.2-2.02.0-1.9-1.92.32.00.42.3-0.8-0.02.2-0.6
Pavlov. Cond. lever-magazine prob. diff.2.22.85.31.9-2.02.0-2.21.81.71.4-1.41.81.8-1.3-1.41.8-0.8-1.4-2.30.1-1.8
Pavlov. Cond. response bias1.01.44.21.3-1.21.2-1.61.11.10.7-0.71.21.2-0.6-0.81.5-0.4-1.2-2.10.2-1.6
Time in closed arm before self-admin4.55.18.42.8-2.62.6-0.92.62.82.8-2.82.92.9-2.7-2.60.8-1.7-0.6-1.4-1.0-1.2
Time in closed arm after self-admin0.30.31.1-0.60.9-0.90.2-1.0-0.4-0.40.4-0.4-0.40.80.60.10.6-0.20.00.7-0.4
Time in open arm before self-admin0.30.31.4-0.10.1-0.10.8-0.10.0-0.10.1-0.3-0.30.2-0.1-0.9-0.10.91.2-0.51.2
Time in open arm after self-admin0.80.92.00.6-0.80.81.30.90.40.3-0.3-0.1-0.1-1.4-0.8-1.1-0.91.11.1-1.41.3
Bone: periosteal estimation1.63.28.6-1.61.9-1.92.9-1.8-1.5-2.02.0-1.6-1.61.71.3-2.20.12.11.6-1.01.7
Bone: periosteal perimeter3.25.312.6-2.62.6-2.63.5-2.5-2.4-2.52.5-2.2-2.22.12.1-2.40.72.02.1-0.81.9
Bone: post-yield work0.50.61.5-0.80.8-0.8-0.6-0.8-0.7-0.90.9-0.4-0.41.20.70.71.0-0.6-0.71.0-0.7
Progressive ratio test 1 active lever presses0.90.92.4-0.70.7-0.7-1.0-0.6-1.0-0.40.4-0.5-0.61.01.11.21.3-1.3-0.81.6-0.9
Progressive ratio test 1 breakpoint0.50.51.6-0.50.6-0.6-0.9-0.5-0.8-0.20.2-0.5-0.50.80.90.91.0-1.0-0.51.3-0.6
Progressive ratio test 1 inactive lever presses2.02.25.8-0.90.9-0.9-1.6-0.8-1.0-0.70.7-0.2-0.10.81.22.22.1-2.4-2.12.4-2.3
Progressive ratio test 2 active lever presses0.60.62.4-0.20.2-0.2-1.60.2-0.30.3-0.30.20.10.60.51.50.5-1.4-1.01.2-0.9
Progressive ratio test 2 breakpoint0.80.92.9-0.30.4-0.5-1.7-0.1-0.50.1-0.1-0.0-0.10.90.61.60.9-1.5-1.21.6-1.2
Progressive ratio test 2 inactive lever presses1.31.65.30.2-0.30.3-2.30.40.00.5-0.50.90.9-0.10.22.30.8-2.1-2.01.5-2.0
Incentive Sensitization - Responses0.50.51.80.1-0.10.1-1.40.40.20.4-0.40.60.60.3-0.11.30.3-1.1-1.20.9-1.0
Incentive Sensitization - Breakpoint0.60.62.1-0.10.1-0.1-1.40.20.00.2-0.20.30.30.50.11.40.5-1.2-1.21.1-1.1
Sum of active levers in priming session hrs 5-60.10.10.20.2-0.20.2-0.10.00.1-0.40.4-0.0-0.0-0.2-0.20.20.2-0.2-0.30.1-0.3
Progressive ratio0.30.31.00.3-0.40.4-1.00.20.70.3-0.30.40.4-0.6-0.30.60.2-0.5-0.90.3-0.8
Food seeking constrained by brief footshock1.21.53.6-1.61.6-1.6-0.1-1.5-1.9-0.70.7-1.5-1.51.71.7-0.11.3-0.20.30.90.1
Seeking ratio, punishment vs. effort0.70.82.5-1.01.1-1.20.5-1.0-1.6-0.60.6-1.0-1.01.51.2-0.10.8-0.10.50.50.3
Retroperitoneal fat weight2.99.415.9-4.03.8-3.82.0-3.9-3.6-3.53.5-4.0-3.93.43.5-0.92.80.11.31.30.7
Reaction time number correct1.42.03.51.4-1.51.50.51.71.21.5-1.51.21.1-1.3-1.5-1.1-1.91.31.3-1.91.5
Reaction time mean minus median0.20.31.1-0.30.6-0.60.5-0.5-0.6-0.50.5-0.3-0.20.30.1-1.1-0.40.70.7-0.60.5
Reaction time mean minus median AUC0.50.71.7-0.91.1-1.10.4-0.9-1.3-1.01.0-1.0-1.00.50.8-0.80.40.30.6-0.10.3
Reaction time num false alarms0.60.82.7-0.00.0-0.01.30.20.40.2-0.20.20.2-0.4-0.6-1.6-1.21.61.3-1.51.3
Reaction time num false alarms AUC0.71.03.00.1-0.10.11.20.30.60.3-0.30.50.5-0.5-0.7-1.6-1.41.71.4-1.61.4
Reaction time trials correct on left1.42.03.51.4-1.51.50.51.71.21.5-1.51.21.1-1.3-1.5-1.1-1.91.31.3-1.91.5
Reaction time trials on left1.52.13.81.4-1.51.50.51.81.21.5-1.51.21.2-1.4-1.5-1.2-1.91.41.3-1.91.6
Reaction time mean0.10.10.40.4-0.20.2-0.30.40.30.4-0.40.60.6-0.4-0.30.0-0.5-0.2-0.3-0.3-0.3
Reaction time mean AUC0.10.10.30.3-0.20.2-0.30.40.20.4-0.40.50.5-0.4-0.30.1-0.3-0.2-0.3-0.0-0.3
Median of all reaction times0.30.40.70.6-0.50.5-0.60.70.60.7-0.70.80.9-0.7-0.50.4-0.4-0.5-0.7-0.1-0.6
Reaction time omissions0.30.41.10.6-0.70.7-0.00.50.50.3-0.30.80.8-0.8-0.7-0.6-1.10.60.6-0.60.6
Reaction time false alarm rate0.10.20.4-0.60.6-0.60.6-0.6-0.1-0.40.4-0.1-0.10.10.1-0.6-0.10.70.4-0.30.3
Reaction time premature initiation rate0.40.52.10.5-0.40.4-0.70.40.80.8-0.80.60.60.3-0.30.80.1-0.6-1.40.2-1.1
Reaction time premature initiations0.40.61.50.9-0.90.9-0.51.01.01.2-1.20.80.8-0.2-0.70.3-0.6-0.1-0.8-0.5-0.4
Std. dev. reaction times0.30.40.8-0.70.9-0.90.6-0.8-0.9-0.70.7-0.5-0.50.50.6-0.9-0.20.50.5-0.30.3
Reaction time trials completed1.52.13.81.4-1.51.50.51.81.21.5-1.51.21.2-1.4-1.5-1.2-1.91.41.3-1.91.6
Reaction time trials AUC1.21.73.41.2-1.31.30.51.61.11.3-1.31.01.0-1.2-1.3-1.1-1.81.31.2-1.91.5
Run reversals in cocaine runway, females1.41.33.00.9-0.90.90.90.91.21.0-1.00.90.9-0.9-1.1-1.3-1.41.61.4-1.71.5
Run reversals in cocaine runway, males0.90.92.5-0.70.7-0.71.2-0.3-1.1-0.70.7-0.9-1.00.60.6-1.3-0.31.31.4-0.61.6
Latency to leave start box in cocaine runway0.20.20.5-0.50.5-0.50.5-0.5-0.6-0.20.2-0.7-0.70.30.40.00.5-0.20.00.5-0.2
Latency to leave start box in cocaine runway, F0.20.30.50.6-0.60.60.40.60.50.7-0.70.40.4-0.6-0.7-0.1-0.40.20.0-0.50.0
Latency to leave start box in cocaine runway, M2.12.03.6-1.71.7-1.7-0.1-1.6-1.7-1.21.2-1.9-1.91.41.60.61.8-1.0-0.41.6-0.7
Std. dev. time between licks in bursts1.11.32.51.3-1.31.3-1.31.31.31.1-1.11.61.6-0.8-1.00.9-0.6-0.6-1.3-0.1-0.9
Total sessions with >9 infusions1.82.04.7-1.71.8-1.8-0.2-1.5-1.8-1.41.4-0.9-0.92.21.90.71.4-1.0-0.51.5-0.7
Short access day 1 total inactive lever presses1.31.53.0-1.41.5-1.4-0.1-1.3-1.6-1.61.6-1.0-1.01.71.60.31.1-0.6-0.71.2-0.6
Short access day 10 total inactive lever presses0.30.40.9-0.70.6-0.60.6-0.8-1.0-0.80.8-0.5-0.50.50.9-0.50.60.30.20.10.2
Short access day 1 total infusions2.02.13.7-1.81.8-1.8-0.3-1.6-1.8-1.61.6-0.9-0.91.91.90.81.5-1.1-0.81.7-1.0
Short access day 10 total infusions1.11.22.2-1.11.2-1.2-0.9-1.0-1.2-0.60.6-1.0-1.01.51.11.01.5-1.2-0.71.4-0.9
Short access total infusions3.13.56.1-2.12.1-2.1-0.9-1.8-2.2-1.71.7-1.3-1.32.42.31.52.3-1.9-1.22.5-1.6
Short access day 1 locomotion0.60.61.8-0.70.7-0.7-0.8-0.7-0.4-0.40.4-0.1-0.10.70.71.11.1-1.1-0.91.3-1.1
Short access day 10 total locomotion0.30.41.2-0.40.5-0.5-0.8-0.3-0.4-0.00.00.10.1-0.00.30.91.1-0.9-0.61.1-1.0
Short access total locomotion2.02.14.6-1.51.6-1.7-1.0-1.4-1.5-1.11.1-1.1-1.01.71.61.32.1-1.5-0.82.1-1.3
One hour access (0.3 mA shock)0.30.31.40.3-0.40.4-0.70.70.01.2-1.20.50.5-0.2-0.30.7-0.4-0.5-0.20.2-0.2
Compulsive drug intake1.51.63.11.5-1.51.5-0.41.61.41.5-1.51.41.3-0.9-1.50.1-1.80.4-0.0-1.00.4
One hour access (shock baseline)0.20.20.4-0.50.4-0.5-0.2-0.3-0.70.3-0.3-0.4-0.40.20.50.40.6-0.6-0.00.6-0.3
Social response proportion0.50.52.2-0.20.2-0.2-0.1-0.5-0.5-0.70.7-0.1-0.00.10.30.80.8-1.1-1.30.9-1.5
Social responses0.20.31.40.1-0.20.21.20.10.10.3-0.30.30.3-0.1-0.5-0.7-0.60.80.5-0.70.6
Social time1.21.62.61.5-1.31.3-1.31.41.41.5-1.51.61.6-1.1-1.51.2-0.5-0.7-0.80.2-0.8
Soleus weight0.10.42.60.4-0.50.5-1.60.40.8-0.20.20.90.90.3-0.40.7-0.2-0.3-0.70.2-0.5
Bone: stiffness1.42.33.6-1.91.9-1.90.3-1.8-1.8-1.51.5-1.5-1.51.91.80.51.8-0.8-0.61.3-0.8
Tibialis anterior weight0.62.03.51.4-1.61.6-1.91.51.71.7-1.71.41.4-1.1-1.21.4-0.3-1.3-1.50.3-1.3
Time to tail flick, vehicle, before self-admin0.30.31.50.00.0-0.00.4-0.20.2-0.70.70.10.10.2-0.3-1.0-0.61.20.7-0.60.9
Time to tail flick, vehicle, after self-admin2.22.34.81.3-1.21.21.51.41.21.2-1.20.40.4-1.6-1.6-2.0-1.82.11.7-2.21.9
Time to tail flick, test, before self-admin0.60.52.2-0.20.2-0.21.1-0.10.20.2-0.20.00.0-0.1-0.2-1.2-0.31.41.5-0.81.4
Time to tail flick, test, after self-admin1.01.01.91.1-1.31.3-0.20.71.41.2-1.21.11.1-1.3-1.2-0.1-1.20.40.2-0.80.3
Delta time to tail flick, vehicle, before/after SA0.20.20.80.4-0.50.5-0.00.60.30.9-0.9-0.2-0.2-0.7-0.30.30.1-0.4-0.4-0.0-0.4
Delta time to tail flick, test, before/after SA2.01.83.51.6-1.71.7-0.71.21.71.2-1.21.91.9-1.6-1.50.4-1.5-0.2-0.7-0.8-0.5
Tibia length0.61.63.4-1.61.5-1.50.8-1.5-1.5-1.61.6-1.6-1.61.81.6-0.60.20.30.4-0.60.5
Ambulatory time before self-admin0.70.82.5-0.20.2-0.2-1.1-0.1-0.20.0-0.00.80.8-0.10.41.61.0-1.5-1.21.3-1.4
Ambulatory time after self-admin0.30.30.70.6-0.50.5-0.90.60.60.6-0.60.80.80.4-0.40.1-0.50.0-0.6-0.4-0.2
Bone: tissue strength0.10.10.2-0.40.2-0.20.4-0.1-0.5-0.30.3-0.3-0.30.40.4-0.10.10.1-0.1-0.10.1
Total heroin consumption0.20.32.1-0.20.1-0.1-1.50.1-0.3-0.60.6-0.3-0.30.60.20.60.2-0.5-0.60.6-0.5
Bone: trabecular number0.20.21.00.1-0.20.20.60.3-0.10.3-0.3-0.5-0.5-0.3-0.1-0.7-0.40.50.8-1.00.7
Bone: trabecular spacing1.01.32.5-1.41.2-1.2-0.0-1.3-1.2-1.21.2-1.0-1.01.61.40.61.4-0.7-0.31.6-0.4
Bone: trabecular thickness0.10.20.80.6-0.40.4-0.00.50.50.4-0.40.40.4-0.9-0.40.0-0.2-0.0-0.3-0.4-0.3
Bone: trabecular tissue density1.11.62.71.6-1.21.2-1.41.41.51.2-1.21.61.6-1.0-1.40.9-0.5-0.8-1.60.1-1.3
Water consumed over 24 hours0.60.72.1-0.91.0-1.00.0-0.9-0.8-1.01.0-1.1-1.11.40.9-0.40.50.20.20.20.2
Number of responses in last shaping day1.61.64.30.9-0.60.6-2.10.40.80.7-0.71.21.3-0.3-0.42.10.5-1.8-2.01.3-2.1