Hub : Genes

Xpnpep3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Xpnpep3 0.17 0.08 9.0e-10 0.17 0.17 0.16 0.17 1.3e-09 2.9e-09 9.2e-09 1.2e-09
2 PL gene expression Xpnpep3 0.2 0.1 0.0e+00 0.17 0.16 0.15 0.17 5.3e-18 7.1e-17 1.8e-16 3.1e-18
3 pVTA isoform ratio XM_039079905.1 0.1 0.06 8.0e-03 0.01 0.01 -0 -0 9.6e-02 1.6e-01 3.7e-01 3.7e-01
4 OFC gene expression Xpnpep3 0.28 0.13 8.3e-05 0.09 0.11 0.02 0.09 3.9e-03 1.3e-03 1.3e-01 4.8e-03
5 Adipose mRNA stability Xpnpep3 0.06 0.04 2.6e-07 0.04 0.04 0.04 0.04 1.6e-05 1.0e-05 1.9e-05 2.4e-05
6 pVTA gene expression Xpnpep3 0.13 0.07 4.7e-05 0.13 0.12 0.11 0.11 3.7e-06 5.2e-06 2.6e-05 1.2e-05
7 NAcc gene expression Xpnpep3 0.08 0.04 1.2e-08 0.07 0.07 0.07 0.07 3.5e-08 3.2e-08 3.0e-08 2.3e-08
8 Adipose isoform ratio XM_039079905.1 0.05 0.03 3.7e-04 0.02 0.03 0.03 0.03 1.6e-03 4.3e-04 2.5e-04 2.3e-04
9 Adipose gene expression Xpnpep3 0.04 0.02 5.0e-04 0.04 0.02 0.03 0.03 4.7e-05 2.7e-03 1.7e-04 2.7e-04
10 LHb gene expression Xpnpep3 0.78 0.11 2.2e-03 -0.01 0.02 0.03 -0.01 8.8e-01 1.0e-01 7.4e-02 7.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.5-0.4-0.5-0.3-0.2-0.30.6-0.7-0.3-0.30.2
Area under the delay curve1.01.05.2-1.0-0.8-1.1-0.4-0.40.3-0.70.8-1.02.3
BMI with tail1.44.56.12.42.42.52.32.3-2.22.11.2-1.2-2.1
BMI without tail0.10.20.90.40.30.60.50.2-0.30.0-0.7-0.2-1.0
Body weight1.77.29.43.13.03.03.03.0-3.02.92.2-1.5-1.3
Weight adjusted by age0.30.31.50.20.20.2-0.5-0.20.10.1-0.31.2-0.9
Bone surface0.20.41.7-0.7-0.7-0.7-0.4-0.30.5-0.50.3-0.51.3
Bone volume0.10.10.6-0.1-0.2-0.20.0-0.00.2-0.20.2-0.50.8
Breakpoint value in progressive ratio session0.10.10.4-0.1-0.1-0.00.1-0.00.4-0.5-0.2-0.7-0.1
Number of licking bursts1.01.22.1-1.3-1.2-1.4-1.3-1.10.7-0.9-0.41.40.1
Context. condit. distance diff. score5.16.210.53.03.03.02.12.2-3.03.20.70.8-2.2
Locomotion velocity, session 10.70.85.0-0.6-0.6-0.7-0.3-0.10.1-0.21.1-0.72.2
Locomotion distance, session 13.14.09.8-2.4-2.3-2.5-1.9-1.71.8-1.80.0-0.23.1
Locomotion velocity, session 20.20.20.30.40.40.40.50.5-0.40.30.6-0.60.2
Locomotion distance, session 22.73.87.2-2.3-2.2-2.3-1.4-1.42.0-2.30.1-1.22.7
Locomotion velocity, session 30.30.42.00.30.20.1-0.3-0.1-0.40.8-0.21.4-0.6
Locomotion distance, session 31.82.03.6-1.5-1.5-1.8-1.9-1.61.0-0.6-0.81.80.8
Stereotopy head waving bouts, day 31.21.42.11.21.21.21.51.4-1.00.81.4-1.40.6
Stereotopy head waving duration, day 33.33.96.12.32.22.32.52.4-1.91.71.7-1.6-0.3
Locomotion velocity, session 70.20.20.50.50.60.50.30.4-0.60.70.30.30.1
Locomotion distance, session 70.30.42.7-0.10.0-0.20.20.2-0.10.00.9-0.61.6
Stereotopy head waving bouts, day 71.82.03.11.71.61.71.31.4-1.61.70.60.3-1.4
Stereotopy head waving duration, day 71.82.24.91.81.61.91.11.1-1.41.7-0.20.8-2.2
Locomotion velocity, session 81.41.62.21.41.31.31.31.5-1.51.31.5-1.00.0
Locomotion distance, session 80.40.71.21.01.01.10.60.6-0.91.1-0.10.6-0.7
Degree of sensitization distance3.73.76.32.12.22.42.52.2-1.61.31.4-1.9-0.4
Degree of sensitization stereotypy1.21.32.31.31.21.30.70.8-1.31.50.10.8-1.4
Conditioned locomotion0.30.30.60.60.70.70.60.6-0.70.80.40.1-0.2
Cocaine response after cond. corrected0.10.10.30.30.30.30.40.4-0.30.10.5-0.40.5
Cocaine response after cond. not corrected0.00.00.10.20.20.20.20.1-0.0-0.1-0.1-0.10.2
Cocaine response before conditioning0.30.41.3-0.4-0.5-0.4-0.6-0.70.6-0.4-1.10.7-0.7
Saline control response0.40.52.0-0.3-0.4-0.2-0.6-0.70.3-0.1-1.21.4-0.5
Bone: connectivity density0.00.00.2-0.1-0.2-0.1-0.0-0.00.2-0.30.1-0.40.2
Bone: cortical apparent density1.01.32.4-1.2-1.3-1.4-1.6-1.30.8-0.7-0.81.3-0.8
Bone: cortical area1.62.43.41.71.51.51.91.8-1.51.31.6-1.60.4
Bone: cortical porosity0.80.81.91.11.11.41.31.0-0.60.60.2-0.7-0.2
Bone: cortical porosity1.71.93.31.61.61.81.81.6-1.21.00.8-1.2-0.2
Bone: cortical thickness0.30.51.10.60.60.40.70.8-0.70.51.0-1.1-0.1
Bone: cortical thickness0.50.61.90.30.40.10.80.8-0.60.31.4-1.40.5
Bone: cortical tissue density1.01.32.4-1.2-1.2-1.4-1.6-1.30.7-0.7-0.81.3-0.8
Condit. Reinf. active minus inactive responses0.10.20.4-0.5-0.5-0.7-0.4-0.40.4-0.30.2-0.10.2
Condit. Reinf. active-inactive response ratio0.10.20.40.30.30.10.10.2-0.50.60.30.4-0.5
Condit. Reinf. active responses1.21.52.1-1.4-1.4-1.4-1.3-1.41.5-1.4-1.00.40.2
Condit. Reinf. inactive responses2.63.14.6-2.0-2.0-1.8-1.7-1.92.1-2.1-1.90.60.4
Incentive salience index mean0.30.40.8-0.8-0.8-0.9-0.7-0.60.7-0.7-0.2-0.10.2
Condit. Reinf. lever presses0.50.71.4-1.0-1.0-1.0-0.8-0.81.0-1.2-0.6-0.20.2
Condit. Reinf. active minus inactive responses0.40.51.4-0.5-0.3-0.6-0.10.1-0.0-0.31.1-1.11.2
Condit. Reinf. active-inactive response ratio0.40.41.80.10.2-0.00.50.6-0.30.11.2-1.30.4
Condit. Reinf. active responses0.30.52.00.20.2-0.00.40.6-0.60.31.4-0.90.9
Condit. Reinf. inactive responses0.40.51.50.50.50.30.50.7-0.90.81.2-0.40.7
Condit. Reinf. lever presses0.20.30.5-0.7-0.7-0.7-0.6-0.50.6-0.7-0.2-0.30.1
Condit. Reinf. lever reinforcers received0.20.31.30.00.1-0.10.30.5-0.30.11.1-0.90.7
Conditioned reinforcement - actives0.20.21.2-0.2-0.1-0.4-0.20.1-0.20.30.8-1.10.4
Conditioned reinforcement - inactives0.60.71.3-1.1-0.9-1.1-0.4-0.40.5-0.90.2-0.91.1
Conditioned locomotion1.61.93.91.21.21.01.41.6-1.41.22.0-1.90.1
Patch foraging indifference point 0 sec0.30.51.4-0.6-0.7-0.5-0.5-0.60.9-1.2-0.6-0.4-0.7
Patch foraging indifference point AUC0.70.83.5-0.9-0.8-1.1-0.6-0.40.1-0.31.1-0.41.9
Delay disc. indifference point, 0s delay1.01.12.61.11.11.31.61.3-0.80.41.0-0.90.6
Delay disc. indifference point, 16s delay1.91.94.0-1.7-1.6-1.9-1.2-1.21.1-1.20.1-0.72.0
Delay disc. indifference point, 2s delay0.60.63.4-0.10.0-0.20.40.4-0.5-0.11.0-1.11.8
Delay disc. indifference point, 24s delay1.31.26.2-0.7-0.7-1.1-0.4-0.10.2-0.11.6-0.92.5
Delay disc. indifference point, 4s delay0.60.73.7-0.5-0.4-0.60.00.00.1-0.60.8-1.11.9
Delay disc. indifference point, 8s delay1.31.44.8-1.4-1.1-1.4-0.9-0.80.8-0.90.1-0.92.2
Indifference point function ln k1.42.05.61.61.51.81.01.0-1.11.5-0.40.6-2.4
Indifference point function log k1.42.05.61.61.51.81.01.0-1.11.5-0.40.6-2.4
Patch foraging total patch changes 0 sec0.40.61.8-0.7-0.9-0.7-0.6-0.71.1-1.4-0.7-0.4-0.5
Patch foraging total patch changes 12 sec0.10.10.6-0.1-0.1-0.20.10.1-0.0-0.30.6-0.80.3
Patch foraging total patch changes 18 sec0.60.72.7-0.4-0.4-0.50.20.10.5-1.00.8-1.61.4
Patch foraging total patch changes 24 sec0.50.61.6-0.8-0.9-1.0-0.4-0.50.4-0.90.1-0.51.3
Patch foraging total patch changes 6 sec0.71.13.2-0.9-0.9-1.0-0.2-0.20.8-1.30.8-1.81.6
Patch foraging time to switch 0 sec0.10.20.50.40.40.60.70.4-0.1-0.1-0.3-0.50.1
Patch foraging water rate 0 sec0.10.20.4-0.4-0.5-0.4-0.5-0.40.6-0.5-0.1-0.2-0.2
Patch foraging water rate 12 sec0.50.81.5-0.8-0.9-0.7-1.0-1.00.9-0.8-1.20.8-0.7
Patch foraging water rate 18 sec0.81.12.2-1.2-1.2-1.1-1.2-1.11.4-1.5-0.5-0.10.5
Patch foraging water rate 24 sec0.10.10.50.40.30.50.10.20.10.0-0.3-0.1-0.7
Patch foraging water rate 6 sec1.62.33.7-1.5-1.5-1.4-1.9-1.81.4-0.9-1.81.8-0.8
Seeking ratio, delayed vs. immediate footshock1.92.23.7-1.4-1.4-1.3-1.5-1.61.9-1.8-1.31.70.2
Distance traveled before self-admin0.00.00.2-0.1-0.00.00.10.0-0.1-0.2-0.1-0.40.5
Distance traveled after self-admin0.40.42.7-0.1-0.00.10.50.40.1-0.50.9-1.60.5
Extensor digitorum longus weight0.20.82.0-0.7-0.8-0.5-0.7-0.91.1-0.9-1.40.6-0.7
Bone: elastic displacement0.00.00.10.0-0.1-0.1-0.1-0.1-0.20.1-0.10.3-0.2
Bone: elastic work2.32.94.72.01.81.92.22.0-1.71.31.4-1.7-0.4
Bone: endosteal estimation0.71.52.51.21.11.21.61.4-0.90.81.2-1.31.3
Bone: endosteal perimeter1.42.94.42.01.92.12.12.0-1.71.71.2-1.00.3
Epididymis fat weight2.76.39.93.03.02.82.62.6-3.13.11.9-0.1-0.4
Delta time in closed arm before/after self-admin0.80.81.50.81.00.70.81.0-0.91.11.2-0.5-0.5
Delta time in open arm before/after self-admin0.50.51.4-0.6-0.7-0.5-0.4-0.60.4-0.9-0.80.41.2
Diff in mean of infusions in LGA sessions0.20.31.1-0.00.10.1-0.10.10.4-0.20.9-0.81.0
Delay discount exponential model param1.11.25.61.10.91.30.60.5-0.40.8-0.70.9-2.4
Extinction: sum of active levers before priming0.10.10.6-0.3-0.1-0.20.10.00.1-0.20.4-0.20.8
Active lever presses in extinction session 60.20.20.30.50.40.50.50.5-0.20.10.40.50.3
Bone: final force2.43.96.41.91.91.82.32.3-1.81.52.5-2.50.7
Bone: final moment2.64.27.01.91.91.92.32.4-1.81.52.6-2.60.8
Food consumed during 24 hour testing period2.12.63.51.61.61.61.91.9-1.71.51.8-1.40.2
Glucose0.20.30.9-0.3-0.4-0.1-0.2-0.50.8-0.9-0.9-0.2-0.3
Heart weight1.72.44.01.71.81.92.01.7-1.31.10.8-1.1-1.8
Delay discount hyperbolic model param1.01.15.41.00.81.10.40.3-0.20.7-0.71.1-2.3
Intermittent access intake day 1-15 change0.80.81.3-1.2-1.0-1.1-1.2-1.10.6-0.5-0.8-0.2-0.8
Intermittent access intake escalation0.80.81.3-1.2-1.0-1.1-1.1-1.10.8-0.6-0.8-0.3-0.6
Intermittent access intake escalation 20.40.40.6-0.8-0.7-0.6-0.6-0.70.7-0.5-0.6-0.4-0.3
Intermitt. access day 1 inactive lever presses0.30.30.60.40.60.80.80.7-0.5-0.10.7-0.5-0.0
Intermitt. access day 15 inactive lever presses0.30.30.80.00.2-0.10.40.5-0.80.30.9-0.60.7
Intermitt. access escalation Index0.20.21.3-0.1-0.1-0.1-0.3-0.10.1-0.3-0.20.4-1.2
Intermittent access day 1 total infusions0.91.12.10.80.80.71.21.2-1.00.41.5-1.30.8
Intermittent access day 15 total infusions0.40.42.2-0.5-0.4-0.6-0.1-0.10.2-0.40.5-1.50.7
Intermittent access terminal intake (last 3 days)0.10.10.9-0.2-0.1-0.30.10.1-0.00.00.4-1.00.3
Intermittent access total infusions0.60.72.20.40.50.30.90.8-0.40.21.2-1.50.9
Intermittent access day 1 locomotion0.60.61.80.80.60.71.00.9-0.50.20.8-1.30.2
Intermittent access day 15 total locomotion0.40.42.00.40.40.40.60.6-0.30.30.8-1.40.5
Intermittent access total locomotion1.01.23.90.80.90.81.21.2-0.70.61.3-2.00.7
Intermittent access standard deviation0.80.83.50.60.70.71.10.9-0.60.40.7-1.9-0.5
Left kidney weight9.727.238.85.95.95.55.45.8-6.26.05.0-2.1-2.2
Right kidney weight10.629.640.16.06.15.75.96.2-6.36.05.5-3.1-1.4
Cocaine induced anxiety1.92.23.61.91.81.91.81.7-1.11.31.1-0.6-0.7
Post-drug Anxiety0.60.71.01.00.91.00.91.0-0.60.60.7-0.6-0.8
Baseline Anxiety1.81.93.2-1.8-1.8-1.8-1.7-1.60.9-1.3-1.10.30.5
Tail length0.10.40.7-0.5-0.5-0.5-0.6-0.70.6-0.6-0.80.60.6
Length with tail0.31.22.21.21.21.01.11.2-1.41.51.2-0.3-0.2
Length without tail1.32.85.11.71.81.41.61.9-2.02.12.3-0.9-0.2
Times rat made contact with spout0.40.51.60.50.50.30.60.7-1.01.01.30.10.1
Lifetime Intake1.11.33.00.90.90.81.31.3-0.80.51.7-1.70.8
Liver weight, left0.60.91.91.11.01.10.70.8-1.11.40.20.7-0.9
Liver weight, right2.33.76.82.32.12.11.21.4-2.02.60.01.7-2.5
Locomotor activity1.42.33.41.71.71.71.71.7-1.81.81.1-0.5-1.0
Locomotor testing distance0.10.20.6-0.3-0.2-0.2-0.4-0.30.20.2-0.40.6-0.8
Locomotor testing rearing0.91.42.31.41.41.41.31.3-1.31.50.7-0.1-0.8
Locomotion in novel chamber3.44.28.1-2.0-2.1-2.0-2.3-2.41.4-1.4-2.81.9-1.7
Locomotion in novel chamber post-restriction0.60.81.3-0.9-0.7-0.5-1.1-1.11.1-0.8-1.20.6-0.2
Fecal boli incidents, locomotor time 10.60.62.7-0.5-0.5-0.60.0-0.00.3-0.70.7-1.21.6
Change in fecal boli incidents, locomotor task0.30.31.10.10.1-0.1-0.30.1-0.91.00.50.7-0.4
Time >=10cm from walls, locomotor time 10.40.50.70.80.70.80.80.8-0.40.40.8-0.30.3
Bouts of movement, locomotor time 11.01.11.81.01.21.01.01.1-0.91.21.40.70.6
Total resting periods, locomotor time 10.70.71.50.81.00.80.90.9-0.70.91.20.40.6
Rest time, locomotor task time 10.80.82.40.60.70.61.00.9-1.00.81.1-1.50.1
Distance moved, locomotor task time 10.30.31.40.70.60.60.30.3-0.20.5-0.40.4-1.2
Vertical activity count, locomotor time 10.10.10.20.20.00.20.10.10.5-0.3-0.30.10.3
Time >=10cm from walls, locomotor time 20.00.00.2-0.1-0.00.2-0.0-0.00.2-0.40.10.0-0.0
Bouts of movement, locomotor time 20.60.71.40.80.80.90.60.7-1.10.80.30.6-1.2
Total resting periods, locomotor time 20.40.40.80.70.70.70.60.7-0.90.60.60.1-0.6
Rest time, locomotor task time 20.30.41.3-0.6-0.5-0.7-0.4-0.3-0.0-0.10.4-1.11.1
Distance moved, locomotor task time 20.50.51.50.80.80.90.70.6-0.60.7-0.20.2-1.2
Vertical activity count, locomotor time 20.30.40.70.80.60.70.90.7-0.30.30.3-0.70.0
Light reinforcement 10.00.10.3-0.2-0.3-0.3-0.1-0.10.3-0.5-0.1-0.10.3
Light reinforcement 20.81.12.91.21.21.30.60.7-0.71.2-0.20.9-1.7
Bone: marrow area0.71.62.71.21.11.31.61.5-0.90.81.3-1.41.3
Bone: maximum diameter3.76.810.02.92.82.83.23.1-2.62.32.6-2.40.3
Bone: maximum force3.66.39.72.42.42.22.92.9-2.31.93.1-3.11.1
Bone: maximum moment3.96.710.32.42.42.33.03.0-2.42.03.2-3.21.1
Mean time between licks in bursts0.60.91.5-0.8-0.8-0.7-0.9-1.01.2-0.9-1.21.2-0.2
Mean num. licks in bursts1.92.33.41.71.71.71.61.7-1.61.81.4-1.0-0.0
Cd content in liver0.60.61.60.80.91.00.40.5-0.81.0-0.0-0.0-1.3
Co content in liver0.20.30.60.40.60.70.60.6-0.40.40.40.2-0.6
Cu content in liver3.13.76.2-2.3-2.2-2.1-1.9-2.12.5-2.4-1.60.10.8
Fe content in liver0.10.10.40.40.30.60.60.30.1-0.2-0.20.00.3
K content in liver0.50.50.9-1.0-0.7-0.7-0.8-0.70.9-0.9-0.40.0-0.2
Mg content in liver0.80.81.7-1.1-1.0-0.8-0.8-0.81.2-1.3-0.6-0.6-0.2
Mn content in liver0.10.10.30.10.10.1-0.3-0.1-0.30.5-0.00.5-0.1
Na content in liver2.12.23.5-1.7-1.7-1.5-1.4-1.61.9-1.8-1.40.30.6
Rb content in liver0.10.10.7-0.2-0.1-0.20.10.10.1-0.20.50.10.9
Se content in liver0.91.12.2-1.0-0.9-0.7-1.5-1.41.0-0.6-1.50.6-0.7
Sr content in liver1.00.91.5-0.9-1.0-0.9-1.2-1.21.0-0.7-1.20.5-0.4
Zn content in liver1.11.21.7-1.3-1.2-1.1-1.2-1.31.3-1.2-1.10.5-0.0
Bone: minimum diameter0.71.22.11.11.01.01.51.3-0.80.81.1-1.31.2
Time in familiar zone, hab. session 10.60.63.5-0.2-0.0-0.20.20.3-0.30.11.1-0.91.9
Time in novel zone, hab. session 11.01.04.61.00.81.10.70.5-0.40.6-0.60.6-2.2
Total zone transitions, hab. session 14.25.99.5-2.9-2.8-3.0-3.1-2.82.3-1.9-1.51.81.3
Total locomotion distance, hab. session 12.73.96.1-2.2-2.3-2.5-2.4-2.31.7-1.4-1.41.91.0
Locomotion velocity, hab. session 13.04.26.9-2.4-2.4-2.6-2.4-2.31.9-1.7-1.31.51.4
Time in familiar zone, hab. session 20.30.31.8-0.0-0.1-0.2-0.4-0.40.00.3-0.71.3-0.4
Time in novel zone, hab. session 20.30.31.40.00.10.20.40.4-0.0-0.20.6-1.20.5
Total zone transitions, hab. session 21.52.04.1-1.7-1.6-1.8-1.2-1.01.2-1.40.3-0.92.0
Total locomotion distance, hab. session 21.01.42.2-1.4-1.4-1.5-0.9-1.01.2-1.5-0.2-0.61.3
Locomotion velocity, hab. session 21.72.33.5-1.8-1.8-1.9-1.3-1.31.6-1.9-0.3-0.61.7
Novel to familiar place preference ratio1.81.83.21.61.51.51.31.3-1.71.80.80.2-0.9
Novelty place preference2.52.54.81.91.81.81.41.5-2.12.20.90.4-1.1
Time in novel zone, NPP test3.13.25.92.12.02.01.61.8-2.32.41.10.3-1.1
Total zone transitions, NPP test3.85.59.8-2.9-2.8-3.1-2.8-2.62.2-2.1-1.01.11.7
Total locomotion distance, NPP test1.82.54.7-1.9-1.9-2.2-1.8-1.61.4-1.5-0.50.51.3
Locomotion velocity, NPP test2.53.66.2-2.3-2.3-2.5-2.1-2.01.8-1.9-1.00.71.4
Intraocular pressure0.30.51.00.70.60.50.50.6-0.90.70.8-0.01.0
Delta distance traveled before/after self-admin0.30.41.60.30.30.30.40.6-0.30.21.3-1.10.4
Delta ambulatory time before/after self-admin0.50.52.20.20.20.20.50.7-0.10.01.5-1.40.6
Parametrial fat weight0.10.20.30.50.50.40.40.4-0.50.50.30.0-0.4
Pavlov. Cond. lever latency0.70.91.51.01.01.01.01.0-1.11.20.9-0.3-0.0
Pavlov. Cond. magazine entry latency0.40.51.1-0.9-0.8-0.9-0.7-0.60.9-1.0-0.0-0.50.6
Pavlov. Cond. change in total contacts1.01.12.0-1.3-1.1-1.2-0.7-0.71.0-1.40.1-1.01.0
Pavlov. Cond. index score0.20.20.5-0.5-0.4-0.5-0.3-0.30.5-0.70.1-0.60.3
Pavlov. Cond. latency score0.10.20.5-0.4-0.4-0.4-0.4-0.30.5-0.7-0.1-0.40.0
Pavlov. Cond. lever contacts0.80.91.9-1.0-1.1-1.0-0.9-1.01.2-1.4-0.8-0.10.4
Pavlov. Cond. magazine entry number0.20.30.60.70.60.80.70.5-0.50.7-0.00.2-0.4
Pavlov. Cond. intertrial magazine entries1.01.21.8-1.3-1.3-1.3-0.8-0.91.3-1.3-0.2-0.61.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.7-0.6-0.7-0.6-0.50.6-0.8-0.1-0.40.3
Pavlov. Cond. response bias0.40.40.9-0.8-0.7-0.8-0.6-0.60.8-1.0-0.1-0.50.5
Pavlov. Cond. lever latency0.81.01.91.11.00.70.91.0-1.31.41.20.10.9
Pavlov. Cond. magazine entry latency2.02.34.2-1.8-1.7-1.6-1.2-1.41.9-2.0-0.6-0.91.2
Pavlov. Cond. change in total contacts0.40.63.5-0.5-0.4-0.20.10.10.8-1.10.3-1.9-0.1
Pavlov. Cond. index score1.31.73.1-1.6-1.5-1.3-1.2-1.31.7-1.8-0.9-0.40.0
Pavlov. Cond. latency score1.62.03.8-1.7-1.7-1.5-1.4-1.41.9-2.0-0.9-0.50.1
Pavlov. Cond. lever contacts0.71.01.6-1.0-1.0-0.7-0.9-1.01.2-1.2-1.20.0-1.3
Pavlov. Cond. magazine entry number0.81.01.91.21.21.00.90.9-1.31.40.40.7-0.6
Pavlov. Cond. intertrial magazine entries1.82.33.11.61.71.41.71.8-1.81.71.6-0.9-0.4
Pavlov. Cond. lever-magazine prob. diff.1.31.63.1-1.5-1.5-1.3-1.2-1.31.7-1.8-1.0-0.40.0
Pavlov. Cond. response bias0.60.81.7-1.0-0.9-0.7-0.7-0.81.1-1.3-0.7-0.7-0.4
Time in closed arm before self-admin2.93.37.9-1.7-1.8-1.3-1.1-1.62.7-2.8-1.4-1.31.8
Time in closed arm after self-admin0.80.82.40.80.80.91.11.0-0.50.40.9-1.50.2
Time in open arm before self-admin0.20.31.10.30.2-0.0-0.3-0.1-0.30.8-0.30.8-1.0
Time in open arm after self-admin0.60.62.1-0.5-0.6-0.4-0.7-0.80.2-0.3-1.41.5-0.2
Bone: periosteal estimation1.53.15.01.81.71.82.22.1-1.51.41.8-1.91.0
Bone: periosteal perimeter3.35.58.22.72.62.72.92.8-2.42.32.0-1.70.3
Bone: post-yield work0.91.24.10.40.30.20.90.9-0.40.11.7-2.01.6
Progressive ratio test 1 active lever presses1.21.23.30.70.70.51.11.1-0.50.31.8-1.81.3
Progressive ratio test 1 breakpoint0.70.72.00.50.60.40.80.9-0.40.31.4-1.40.9
Progressive ratio test 1 inactive lever presses0.30.30.90.40.50.51.00.7-0.4-0.10.6-0.8-0.1
Progressive ratio test 2 active lever presses0.40.51.9-0.4-0.2-0.5-0.10.10.3-0.31.0-1.11.4
Progressive ratio test 2 breakpoint0.40.51.7-0.10.1-0.20.20.40.1-0.11.2-1.31.1
Progressive ratio test 2 inactive lever presses0.60.71.5-1.0-0.8-1.0-0.5-0.60.7-1.10.1-0.61.2
Incentive Sensitization - Responses0.50.51.0-0.9-0.7-1.0-1.0-0.80.7-0.6-0.40.3-0.4
Incentive Sensitization - Breakpoint0.30.30.6-0.7-0.5-0.8-0.8-0.60.5-0.4-0.20.2-0.5
Sum of active levers in priming session hrs 5-60.00.00.20.10.10.10.1-0.00.1-0.2-0.30.1-0.4
Progressive ratio0.10.10.9-0.1-0.10.10.1-0.10.3-0.4-0.1-0.60.9
Food seeking constrained by brief footshock1.21.43.70.91.21.11.31.3-1.91.11.4-0.4-0.2
Seeking ratio, punishment vs. effort0.40.51.30.50.60.40.70.8-1.20.71.0-0.4-0.6
Retroperitoneal fat weight4.013.219.14.44.34.13.63.9-4.14.32.8-0.5-2.2
Reaction time number correct1.21.73.0-1.3-1.3-1.3-1.7-1.51.3-0.9-1.11.7-0.1
Reaction time mean minus median0.10.10.10.30.20.30.30.2-0.30.2-0.40.1-0.3
Reaction time mean minus median AUC0.60.81.31.11.01.00.90.7-1.11.0-0.20.3-0.8
Reaction time num false alarms0.10.20.5-0.2-0.3-0.1-0.2-0.40.4-0.6-0.70.5-0.3
Reaction time num false alarms AUC0.30.40.7-0.6-0.6-0.4-0.6-0.70.7-0.8-0.80.8-0.1
Reaction time trials correct on left1.21.73.0-1.3-1.3-1.3-1.7-1.51.3-0.9-1.11.7-0.1
Reaction time trials on left1.31.93.2-1.4-1.4-1.4-1.8-1.61.4-1.0-1.21.8-0.1
Reaction time mean0.20.20.7-0.2-0.2-0.1-0.2-0.30.5-0.5-0.90.4-0.8
Reaction time mean AUC0.10.20.5-0.2-0.2-0.2-0.2-0.40.4-0.4-0.70.4-0.7
Median of all reaction times0.20.30.7-0.4-0.4-0.3-0.4-0.50.7-0.7-0.90.4-0.7
Reaction time omissions0.40.60.8-0.8-0.8-0.8-0.9-0.90.8-0.8-0.80.80.1
Reaction time false alarm rate0.00.10.10.20.20.40.30.1-0.0-0.2-0.30.0-0.4
Reaction time premature initiation rate0.20.31.9-0.1-0.1-0.00.30.30.6-0.60.4-1.40.2
Reaction time premature initiations0.20.20.9-0.5-0.5-0.4-0.3-0.30.9-0.70.1-0.50.2
Std. dev. reaction times0.20.20.70.50.50.50.50.3-0.60.4-0.30.2-0.8
Reaction time trials completed1.31.93.2-1.4-1.4-1.4-1.8-1.61.4-1.0-1.21.8-0.1
Reaction time trials AUC0.91.32.4-1.1-1.1-1.1-1.5-1.31.2-0.8-1.01.5-0.1
Run reversals in cocaine runway, females1.11.12.5-1.0-1.1-1.0-1.2-1.11.0-0.7-1.01.6-0.2
Run reversals in cocaine runway, males0.60.62.80.50.40.20.30.5-0.80.91.0-0.21.7
Latency to leave start box in cocaine runway0.60.62.10.90.90.90.60.6-0.60.8-0.10.1-1.5
Latency to leave start box in cocaine runway, F0.20.20.6-0.1-0.2-0.2-0.4-0.50.4-0.2-0.80.4-0.8
Latency to leave start box in cocaine runway, M2.42.33.11.61.81.71.51.5-1.61.70.8-0.9-1.7
Std. dev. time between licks in bursts1.11.32.8-1.3-1.3-1.3-0.9-1.01.7-1.6-0.5-0.10.7
Total sessions with >9 infusions1.82.03.91.31.41.21.51.7-1.31.22.0-1.50.3
Short access day 1 total inactive lever presses1.21.43.40.20.40.21.31.2-1.00.21.8-1.51.8
Short access day 10 total inactive lever presses0.10.10.60.20.20.30.40.4-0.80.40.3-0.10.1
Short access day 1 total infusions0.80.81.40.91.00.81.11.2-1.10.61.1-0.3-0.1
Short access day 10 total infusions2.12.44.41.61.61.61.81.8-0.80.91.9-2.10.2
Short access total infusions2.52.84.41.71.81.72.12.1-1.51.12.1-1.60.1
Short access day 1 locomotion0.10.20.40.40.50.50.60.5-0.20.20.3-0.1-0.3
Short access day 10 total locomotion0.20.20.80.10.00.40.30.0-0.2-0.3-0.8-0.8-0.9
Short access total locomotion1.61.62.51.41.41.51.61.5-1.10.81.1-1.2-0.9
One hour access (0.3 mA shock)0.40.50.8-0.9-0.8-0.9-0.6-0.60.7-0.8-0.2-0.70.5
Compulsive drug intake2.32.44.0-1.8-1.9-2.0-2.0-1.71.3-1.5-0.70.41.0
One hour access (shock baseline)0.20.20.50.50.60.60.70.5-0.00.40.3-0.5-0.4
Social response proportion0.60.62.90.80.60.90.80.6-0.20.1-0.4-0.5-1.7
Social responses0.10.10.3-0.4-0.5-0.5-0.3-0.30.3-0.40.1-0.20.6
Social time1.52.03.1-1.8-1.7-1.6-1.4-1.51.6-1.7-1.00.00.6
Soleus weight0.30.81.8-1.1-1.1-1.3-1.0-0.80.8-0.90.3-0.30.9
Bone: stiffness2.64.17.31.91.92.02.52.4-1.61.32.3-2.70.9
Tibialis anterior weight0.41.42.6-1.4-1.4-1.3-1.1-1.21.6-1.6-0.8-0.30.6
Time to tail flick, vehicle, before self-admin0.20.20.9-0.0-0.2-0.40.10.10.00.10.6-0.51.0
Time to tail flick, vehicle, after self-admin1.21.32.4-1.1-1.1-1.0-1.0-1.11.1-0.9-0.91.51.3
Time to tail flick, test, before self-admin0.20.20.9-0.1-0.1-0.4-0.00.0-0.50.20.30.41.0
Time to tail flick, test, after self-admin1.11.11.5-1.2-1.2-1.2-1.2-1.21.0-1.2-1.00.80.3
Delta time to tail flick, vehicle, before/after SA0.20.21.1-0.3-0.20.0-0.1-0.30.3-0.4-0.61.0-0.2
Delta time to tail flick, test, before/after SA2.82.53.9-1.7-1.6-1.3-1.7-1.82.0-1.7-1.71.3-0.3
Tibia length0.82.24.81.31.31.01.51.7-1.61.52.2-1.40.9
Ambulatory time before self-admin0.30.30.5-0.7-0.6-0.7-0.5-0.60.0-0.5-0.50.20.5
Ambulatory time after self-admin0.80.91.7-1.2-1.2-1.1-0.7-0.70.8-1.30.1-0.61.0
Bone: tissue strength0.10.10.20.50.30.40.30.4-0.30.40.4-0.2-0.2
Total heroin consumption0.10.20.60.20.30.20.30.4-0.2-0.00.8-0.60.5
Bone: trabecular number0.10.10.50.20.10.2-0.1-0.0-0.30.4-0.20.7-0.4
Bone: trabecular spacing1.72.14.71.01.20.91.61.6-1.40.92.2-2.11.1
Bone: trabecular thickness0.30.41.5-0.1-0.2-0.0-0.4-0.50.7-0.4-1.20.8-0.9
Bone: trabecular tissue density1.01.43.1-1.2-1.1-0.9-0.9-1.11.8-1.7-1.2-0.1-0.5
Water consumed over 24 hours0.60.71.80.60.60.50.70.9-1.11.01.4-0.20.4
Number of responses in last shaping day1.31.45.1-0.8-0.5-0.40.1-0.21.1-1.50.4-2.32.0