Hub : Genes

Xpnpep1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio NM_001398660.1 0.03 0.02 3.6e-03 0.02 0.02 0.01 0.01 2.6e-03 2.7e-03 1.6e-02 6.9e-03
2 Adipose mRNA stability Xpnpep1 0.09 0.04 8.1e-08 0.06 0.05 0.05 0.05 3.6e-07 4.8e-06 1.6e-06 2.8e-06
3 LHb mRNA stability Xpnpep1 0.18 0.1 7.2e-03 0.06 0.06 0.07 0.08 1.3e-02 1.7e-02 9.4e-03 7.4e-03
4 PL alternative TSS XM_039084410.1 0.03 0.02 6.8e-03 0 0.01 0 0.01 9.1e-02 9.1e-03 8.6e-02 4.6e-02
5 BLA gene expression Xpnpep1 0.09 0.05 1.1e-03 0.06 0.04 0.04 0.04 4.5e-04 2.0e-03 4.8e-03 2.4e-03
6 Brain mRNA stability Xpnpep1 0.13 0.05 1.1e-11 0.08 0.12 0.12 0.12 2.9e-08 2.5e-11 4.1e-11 8.3e-11
7 Brain intron excision ratio chr1_252036511_252051365 0.03 0.02 6.9e-03 0.03 0.02 0.02 0.03 4.9e-04 5.6e-03 5.7e-03 9.3e-04
8 Liver intron excision ratio chr1_252036511_252051365 0.03 0.02 6.1e-03 0.01 0.01 -0 0.01 2.9e-02 3.4e-02 6.3e-01 3.6e-02
9 Liver gene expression Xpnpep1 0.18 0.08 3.8e-14 0.08 0.1 0.09 0.09 2.2e-09 1.0e-10 2.3e-10 1.7e-10
10 pVTA gene expression Xpnpep1 0.19 0.12 4.8e-03 0 0.02 0.06 0.02 2.7e-01 5.1e-02 1.5e-03 4.9e-02
11 BLA alternative TSS XM_039084410.1 0.05 0.03 2.0e-03 0.02 0.06 0.04 0.04 3.4e-02 6.0e-04 4.1e-03 4.3e-03
12 BLA intron excision ratio chr1_252024607_252036387 0.06 0.03 1.5e-03 0 0.02 0 0 3.0e-01 4.4e-02 1.6e-01 3.1e-01
13 BLA isoform ratio NM_131913.3 0.06 0.03 3.8e-03 0.04 0.04 0.04 0.03 5.0e-03 4.6e-03 2.1e-03 6.5e-03
14 PL isoform ratio XM_039084410.1 0.04 0.03 6.9e-03 0.01 0.01 0 0.01 1.7e-02 1.8e-02 9.0e-02 7.1e-02
15 PL mRNA stability Xpnpep1 0.1 0.04 3.5e-12 0.12 0.12 0.1 0.12 4.1e-13 1.3e-12 1.3e-10 6.6e-13
16 NAcc alternative TSS XM_039084410.1 0.02 0.01 9.6e-03 0.01 0.01 0.01 0 6.1e-02 5.8e-02 5.3e-02 1.0e-01
17 PL gene expression Xpnpep1 0.12 0.05 1.9e-13 0.14 0.13 0.13 0.13 7.2e-15 3.1e-14 5.2e-14 3.2e-14
18 BLA intron excision ratio chr1_252036511_252051365 0.05 0.03 5.9e-03 0.04 0.01 0.02 0.02 3.5e-03 5.7e-02 2.0e-02 3.0e-02
19 BLA alternative TSS NM_131913.3 0.04 0.03 8.6e-03 0 0.04 0.02 0.02 1.7e-01 4.6e-03 2.8e-02 3.0e-02
20 NAcc intron excision ratio chr1_252012810_252013843 0.03 0.02 2.9e-03 0.02 0.01 0.01 0 4.0e-03 4.7e-02 4.3e-02 1.4e-01
21 NAcc alternative TSS XM_039084410.1 0.02 0.01 1.3e-03 0 0.02 0.01 0.01 1.4e-01 3.4e-03 1.2e-02 4.5e-02
22 Adipose gene expression Xpnpep1 0.19 0.07 0.0e+00 0.18 0.17 0.18 0.18 4.4e-19 4.5e-18 4.0e-19 3.7e-19
23 IL gene expression Xpnpep1 0.3 0.13 1.5e-05 0.28 0.23 0.22 0.21 1.6e-07 2.8e-06 5.7e-06 1.1e-05
24 NAcc mRNA stability Xpnpep1 0.04 0.02 5.1e-05 0.02 0.04 0.04 0.04 8.5e-04 4.1e-05 4.7e-05 4.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.50.94.0-2.0-1.81.80.7-1.61.21.70.31.00.90.3-0.70.50.4-0.6-0.20.4-0.0-0.2-0.20.70.20.20.3
Area under the delay curve1.21.33.5-1.8-1.91.91.3-1.21.41.40.71.31.00.5-0.61.0-0.1-0.6-0.40.90.9-0.3-1.40.61.11.41.0
BMI with tail1.34.110.3-3.1-3.22.8-0.3-0.83.00.70.52.41.0-1.51.0-0.62.3-2.51.72.6-1.01.6-2.5-1.02.42.42.4
BMI without tail1.12.38.1-2.8-2.82.51.4-1.62.31.61.22.10.40.3-0.51.50.7-1.5-0.31.31.4-0.1-0.90.40.80.91.6
Body weight1.66.618.2-4.1-4.13.8-0.7-1.54.31.4-0.82.53.8-1.70.80.03.6-2.90.92.7-0.51.8-2.8-0.42.52.72.7
Weight adjusted by age0.30.41.5-1.0-0.91.20.5-0.50.50.5-0.40.4-0.40.3-0.11.00.7-0.5-0.10.91.0-0.5-0.10.20.30.10.7
Bone surface0.20.31.5-0.6-0.50.6-0.4-0.30.40.2-0.20.21.2-0.60.4-0.90.5-0.30.70.4-1.20.6-0.4-0.30.40.40.3
Bone volume0.50.94.7-1.7-1.61.60.0-1.11.41.2-0.50.72.2-0.2-0.10.11.1-0.70.20.5-0.40.3-0.60.30.60.60.6
Breakpoint value in progressive ratio session0.60.61.7-1.1-1.11.01.3-1.10.51.10.60.60.20.9-0.91.2-0.50.0-0.50.11.1-0.80.30.8-0.3-0.30.2
Number of licking bursts0.40.53.1-0.6-0.80.60.2-1.10.51.1-1.2-0.31.80.5-0.70.80.60.4-0.70.10.5-0.60.01.0-0.1-0.1-0.2
Context. condit. distance diff. score0.50.62.31.31.5-1.4-0.50.8-1.5-0.7-0.5-1.2-0.70.10.4-0.8-0.30.70.6-0.7-0.8-0.30.4-0.3-0.4-0.4-0.6
Locomotion velocity, session 12.22.44.80.90.9-0.81.3-1.0-1.31.0-0.3-1.2-0.42.0-1.81.9-1.51.8-2.2-1.72.0-2.11.81.8-1.9-1.9-1.6
Locomotion distance, session 10.40.51.61.01.0-0.9-0.40.6-0.9-0.6-1.3-1.1-0.70.40.00.60.50.5-0.5-0.51.0-0.80.70.2-0.6-0.7-0.5
Locomotion velocity, session 20.60.72.51.10.9-1.2-1.21.6-0.7-1.6-1.0-0.7-1.0-0.71.1-0.60.9-0.21.00.1-0.30.40.2-0.90.1-0.20.1
Locomotion distance, session 20.71.05.20.70.8-0.8-0.60.1-0.4-0.0-2.3-1.51.50.5-0.41.20.90.8-1.2-0.81.3-0.91.00.9-1.0-1.0-0.7
Locomotion velocity, session 30.80.92.21.41.1-1.1-0.20.3-1.1-0.2-1.5-1.50.20.7-0.40.70.11.1-0.9-1.00.9-1.01.20.7-1.2-1.2-1.0
Locomotion distance, session 32.02.26.61.81.7-1.6-0.3-0.1-1.60.1-2.6-2.41.41.2-0.70.80.31.8-1.2-2.00.9-1.61.81.3-1.8-1.7-1.4
Stereotopy head waving bouts, day 30.20.21.20.1-0.3-0.0-0.10.50.3-0.51.10.8-0.5-0.60.2-0.4-0.5-0.3-0.10.7-0.40.8-0.3-0.60.20.20.2
Stereotopy head waving duration, day 30.30.42.50.2-0.0-0.10.20.4-0.3-0.31.60.7-1.6-0.2-0.0-0.7-1.1-0.00.00.5-0.70.4-0.0-0.50.1-0.1-0.3
Locomotion velocity, session 71.01.12.30.70.7-0.70.5-0.7-1.30.7-0.8-1.3-0.31.3-1.00.5-0.71.4-0.8-1.30.4-1.51.41.1-1.3-1.4-1.3
Locomotion distance, session 70.91.13.91.61.6-1.6-0.80.5-1.7-0.5-1.9-2.0-0.10.40.1-0.50.31.20.1-1.1-0.5-0.80.90.3-0.8-0.9-1.1
Stereotopy head waving bouts, day 70.50.61.70.70.6-0.6-0.4-0.3-0.30.2-0.2-0.51.20.0-0.6-0.3-0.60.9-1.3-1.0-0.50.21.10.5-1.3-1.1-1.2
Stereotopy head waving duration, day 70.50.61.70.40.3-0.20.2-0.7-0.20.70.1-0.30.90.4-0.90.1-0.90.9-1.3-1.0-0.2-0.21.10.8-1.3-1.1-1.1
Locomotion velocity, session 80.30.31.00.70.9-0.8-0.50.6-0.9-0.6-0.4-0.8-1.0-0.00.2-0.50.10.30.2-0.3-0.4-0.20.6-0.2-0.5-0.7-0.6
Locomotion distance, session 80.71.03.51.41.7-1.6-0.90.9-1.4-0.8-1.8-1.9-0.10.20.20.00.60.8-0.1-0.90.2-0.70.90.2-0.9-0.9-0.9
Degree of sensitization distance0.50.52.9-0.5-0.50.30.8-0.1-0.20.11.50.8-1.70.10.1-0.5-1.0-0.30.90.7-0.60.0-0.6-0.40.70.60.3
Degree of sensitization stereotypy1.31.43.51.21.2-1.1-0.6-0.5-0.80.4-1.0-1.41.70.3-0.8-0.4-0.51.5-1.4-1.8-0.7-0.31.70.9-1.9-1.6-1.7
Conditioned locomotion1.11.34.51.51.7-1.7-1.70.9-0.8-0.7-2.1-1.72.1-0.60.3-0.90.71.1-0.4-0.8-1.10.40.60.1-0.7-0.6-1.1
Cocaine response after cond. corrected0.70.86.31.21.1-0.90.21.4-1.1-1.41.0-0.0-2.5-0.10.7-0.2-0.90.10.60.10.40.0-0.1-0.90.20.10.2
Cocaine response after cond. not corrected1.21.37.91.81.7-1.4-0.41.8-1.8-1.80.6-0.6-2.8-0.30.9-0.9-0.90.41.1-0.1-0.40.20.3-1.2-0.1-0.4-0.3
Cocaine response before conditioning0.30.41.70.70.7-0.6-0.70.3-0.9-0.2-0.4-0.7-0.5-0.20.2-1.1-0.20.50.6-0.3-1.30.10.7-0.2-0.5-0.7-0.9
Saline control response0.40.62.01.41.3-1.3-0.40.8-1.2-1.0-0.2-0.9-0.7-0.10.4-0.6-0.40.60.1-0.9-0.4-0.00.5-0.3-0.5-0.5-0.5
Bone: connectivity density0.20.31.1-1.0-0.70.80.1-0.30.50.30.50.70.0-0.30.2-0.50.2-0.60.80.6-0.80.4-0.5-0.30.50.50.5
Bone: cortical apparent density0.81.03.31.71.8-1.6-1.41.6-1.0-1.6-1.3-1.3-0.7-0.50.9-0.60.60.30.1-0.5-0.10.30.3-0.6-0.3-0.3-0.4
Bone: cortical area0.81.25.50.70.8-1.1-1.1-0.3-1.00.3-2.3-1.82.2-0.10.0-1.20.61.10.4-0.9-1.8-0.20.60.4-0.6-0.6-1.2
Bone: cortical porosity0.60.61.7-0.7-0.70.71.3-1.10.11.11.30.7-0.90.9-1.10.7-1.30.3-0.9-0.10.6-0.60.30.7-0.4-0.3-0.4
Bone: cortical porosity0.60.61.8-0.7-0.60.71.1-1.30.21.30.70.4-0.00.9-1.20.8-1.00.4-1.2-0.30.6-0.70.41.0-0.5-0.4-0.5
Bone: cortical thickness1.62.710.32.02.1-2.3-2.40.8-1.7-0.9-3.2-2.61.6-0.70.7-2.01.01.30.5-1.1-2.40.31.0-0.1-0.9-0.9-1.7
Bone: cortical thickness1.61.87.51.71.7-1.9-2.41.1-0.8-1.1-2.7-1.91.9-1.00.8-1.41.30.80.2-0.7-1.60.70.5-0.3-0.5-0.4-1.1
Bone: cortical tissue density0.70.93.01.61.7-1.5-1.31.6-0.9-1.6-1.2-1.2-0.7-0.50.8-0.40.50.30.0-0.50.00.20.3-0.6-0.3-0.3-0.3
Condit. Reinf. active minus inactive responses1.31.53.30.60.5-0.61.4-1.0-0.61.00.4-0.51.11.5-1.51.5-1.71.5-1.8-1.41.6-1.31.11.4-1.2-1.0-0.9
Condit. Reinf. active-inactive response ratio0.50.52.60.30.3-0.41.3-0.4-0.60.41.20.0-0.51.0-0.80.7-1.60.8-0.6-0.70.8-0.80.50.6-0.5-0.4-0.3
Condit. Reinf. active responses2.02.45.40.80.6-0.81.3-1.5-0.81.4-0.2-1.02.11.7-2.01.6-1.82.0-2.3-2.01.5-1.51.62.0-1.8-1.6-1.5
Condit. Reinf. inactive responses1.01.24.50.30.1-0.30.5-1.2-0.21.2-0.6-0.72.10.9-1.41.0-0.71.2-1.8-1.30.7-0.81.21.4-1.4-1.2-1.2
Incentive salience index mean1.82.25.00.70.5-0.71.8-1.2-0.81.20.3-0.60.92.0-1.82.1-1.91.8-2.2-1.62.2-1.81.31.8-1.4-1.2-1.1
Condit. Reinf. lever presses1.31.85.7-0.0-0.40.21.6-1.5-0.11.5-0.0-0.20.31.8-1.82.3-1.01.1-2.1-0.92.4-1.80.91.8-1.0-1.0-0.7
Condit. Reinf. active minus inactive responses5.66.915.70.30.2-0.53.7-3.3-1.93.01.2-1.00.43.8-3.62.5-4.03.0-2.7-2.92.0-3.52.53.3-2.6-2.4-2.3
Condit. Reinf. active-inactive response ratio3.33.510.00.90.8-1.02.6-2.0-2.01.81.0-1.10.32.7-2.31.3-3.22.4-1.4-2.40.9-2.51.82.1-1.8-1.7-1.8
Condit. Reinf. active responses4.36.011.80.10.0-0.33.2-3.2-1.53.00.8-1.00.53.4-3.42.1-3.42.7-2.9-2.71.5-3.22.53.2-2.7-2.4-2.3
Condit. Reinf. inactive responses1.31.64.4-0.4-0.40.31.4-1.7-0.21.60.1-0.30.01.7-1.91.4-1.21.1-2.1-1.21.1-1.61.41.8-1.5-1.4-1.1
Condit. Reinf. lever presses3.34.58.11.31.4-1.51.5-1.6-2.21.6-0.8-2.1-0.22.6-2.41.5-2.22.8-2.4-2.81.2-2.72.72.5-2.8-2.7-2.6
Condit. Reinf. lever reinforcers received4.25.912.30.40.3-0.53.1-2.9-1.72.70.9-1.10.33.4-3.32.1-3.52.8-2.8-2.71.6-3.22.53.1-2.7-2.5-2.4
Conditioned reinforcement - actives0.90.93.0-1.2-1.31.31.4-0.51.10.41.71.5-0.70.4-0.31.1-0.4-0.8-0.10.81.3-0.1-0.90.00.71.01.2
Conditioned reinforcement - inactives0.50.62.6-0.3-0.30.20.3-1.20.21.1-0.5-0.31.60.6-1.10.6-0.40.7-1.1-0.50.2-0.50.61.1-0.9-0.6-0.8
Conditioned locomotion2.73.26.9-1.8-1.92.0-0.20.82.4-0.91.22.3-1.3-1.41.30.01.7-2.51.02.60.41.5-2.6-1.42.52.52.5
Patch foraging indifference point 0 sec1.22.09.61.31.2-1.5-2.21.4-0.5-1.3-0.8-0.61.1-1.91.4-2.80.30.11.40.1-3.11.9-0.2-1.50.20.2-0.4
Patch foraging indifference point AUC1.21.32.70.50.3-0.7-0.1-0.9-0.91.0-1.6-1.51.11.0-1.20.6-0.01.4-1.3-1.40.3-1.31.51.5-1.5-1.6-1.6
Delay disc. indifference point, 0s delay0.50.61.6-1.2-1.21.30.6-0.71.00.90.10.71.00.3-0.41.00.2-0.4-0.40.50.9-0.2-1.00.50.71.00.5
Delay disc. indifference point, 16s delay0.70.71.8-1.2-1.21.21.3-1.00.91.11.11.10.50.6-0.70.8-0.7-0.3-0.50.40.8-0.3-0.80.50.60.80.6
Delay disc. indifference point, 2s delay0.30.40.9-0.8-0.90.80.6-0.60.60.7-0.40.30.60.4-0.30.90.5-0.2-0.10.40.9-0.5-0.60.50.60.60.6
Delay disc. indifference point, 24s delay1.61.64.2-2.0-2.02.11.9-1.91.22.00.71.00.71.3-1.31.4-0.4-0.2-0.80.21.1-1.1-0.11.3-0.10.10.5
Delay disc. indifference point, 4s delay0.50.51.2-0.9-0.80.90.9-0.90.51.10.10.40.70.8-0.81.0-0.20.1-0.80.00.8-0.8-0.40.90.30.40.1
Delay disc. indifference point, 8s delay1.61.64.9-2.0-2.22.21.1-1.21.81.20.91.60.90.1-0.30.80.1-1.0-0.11.30.70.1-1.70.31.41.71.3
Indifference point function ln k0.50.61.5-0.2-0.20.3-0.20.60.3-0.51.10.9-0.7-0.90.8-1.0-0.2-0.81.21.0-1.01.1-0.9-1.11.00.90.7
Indifference point function log k0.50.61.5-0.2-0.20.3-0.20.60.3-0.51.10.9-0.7-0.90.8-1.0-0.2-0.81.21.0-1.01.1-0.9-1.11.00.90.7
Patch foraging total patch changes 0 sec0.91.58.61.21.1-1.4-2.00.9-0.6-0.8-1.0-0.81.3-1.51.0-2.50.20.40.9-0.3-2.91.50.3-0.9-0.2-0.3-0.9
Patch foraging total patch changes 12 sec0.81.02.60.70.5-1.1-0.6-0.5-0.90.5-1.6-1.40.60.5-0.7-0.20.01.2-1.1-1.2-0.6-0.71.40.9-1.4-1.5-1.6
Patch foraging total patch changes 18 sec1.11.43.90.90.7-1.4-0.5-0.8-1.00.8-1.3-1.51.70.5-1.0-0.4-0.61.6-1.4-1.4-1.0-0.51.41.2-1.5-1.4-2.0
Patch foraging total patch changes 24 sec0.70.92.10.10.1-0.5-0.2-1.0-0.61.1-1.1-1.11.40.6-0.9-0.1-0.21.1-0.8-1.3-0.7-0.71.21.1-1.3-1.3-1.4
Patch foraging total patch changes 6 sec1.01.55.61.11.0-1.3-2.40.8-0.5-0.8-1.8-1.21.8-1.50.9-1.80.90.50.6-0.4-2.31.30.3-0.7-0.3-0.4-1.0
Patch foraging time to switch 0 sec0.50.82.7-0.8-0.70.80.90.10.7-0.31.61.4-1.5-0.10.40.4-0.1-1.00.61.20.80.2-1.1-0.61.21.21.3
Patch foraging water rate 0 sec0.30.52.90.50.4-0.5-1.00.0-0.20.1-1.4-0.91.7-0.3-0.1-0.50.40.5-0.4-0.7-0.70.20.60.3-0.7-0.6-0.9
Patch foraging water rate 12 sec0.40.62.1-1.1-1.10.9-0.2-0.40.90.50.61.01.0-0.80.3-1.00.0-0.60.80.5-1.41.1-0.7-0.40.70.70.4
Patch foraging water rate 18 sec0.20.30.6-0.4-0.10.5-0.50.60.6-0.40.00.40.2-0.80.7-0.40.5-0.70.60.6-0.20.8-0.8-0.70.80.80.7
Patch foraging water rate 24 sec0.30.41.3-0.8-0.60.9-0.00.20.8-0.1-0.10.50.4-0.40.60.20.9-0.90.80.70.40.3-0.9-0.40.90.91.2
Patch foraging water rate 6 sec0.10.10.4-0.2-0.30.3-0.30.30.4-0.30.00.3-0.3-0.50.4-0.30.4-0.60.40.4-0.10.5-0.4-0.50.50.40.4
Seeking ratio, delayed vs. immediate footshock1.01.12.8-0.3-0.20.3-1.01.10.9-1.1-0.70.50.2-1.31.4-0.41.7-1.21.21.2-0.01.2-1.5-1.21.51.51.3
Distance traveled before self-admin0.80.93.11.71.8-1.6-1.41.0-1.0-1.1-1.5-1.40.3-0.50.6-0.40.30.60.1-0.6-0.10.30.5-0.4-0.3-0.5-0.7
Distance traveled after self-admin1.31.53.30.00.20.1-1.41.50.7-1.8-0.70.3-0.5-1.61.8-0.21.8-1.41.11.10.41.4-1.3-1.61.61.31.4
Extensor digitorum longus weight0.52.14.8-0.6-0.60.40.5-2.0-0.02.0-2.1-1.22.21.5-1.71.70.51.3-1.7-0.91.2-1.81.32.2-1.3-1.3-1.2
Bone: elastic displacement0.30.31.2-0.4-0.30.40.6-0.50.40.40.80.5-0.40.4-0.70.8-0.60.0-1.10.00.9-0.30.40.5-0.5-0.5-0.2
Bone: elastic work0.30.31.1-0.6-0.40.7-0.40.21.1-0.3-0.30.50.8-0.50.30.50.9-0.7-0.30.80.70.5-0.6-0.20.50.50.6
Bone: endosteal estimation0.81.75.9-2.1-2.12.40.9-0.81.80.91.21.81.1-0.30.20.40.5-1.40.81.40.20.5-1.5-0.31.51.51.7
Bone: endosteal perimeter0.30.63.6-1.2-1.21.20.0-0.81.10.8-0.90.31.9-0.20.00.31.1-0.50.30.6-0.00.1-0.70.20.70.70.7
Epididymis fat weight1.73.914.4-3.5-3.63.20.9-2.83.12.7-0.51.83.80.1-1.01.41.6-1.2-0.71.30.70.0-1.01.30.81.01.2
Delta time in closed arm before/after self-admin0.90.92.91.71.4-1.5-0.81.4-1.0-1.6-0.1-0.6-0.6-0.61.0-1.2-0.20.31.2-0.1-1.00.5-0.2-1.00.30.30.1
Delta time in open arm before/after self-admin0.70.72.2-1.5-1.31.31.2-1.20.41.41.00.7-0.90.8-0.90.8-0.6-0.3-0.50.20.6-0.70.10.7-0.1-0.2-0.1
Diff in mean of infusions in LGA sessions0.40.52.70.70.7-0.70.8-0.1-1.00.21.3-0.0-1.10.5-0.4-0.2-1.60.6-0.1-0.5-0.2-0.30.50.0-0.5-0.5-0.5
Delay discount exponential model param1.31.43.91.92.0-2.0-1.41.4-1.5-1.5-0.6-1.3-1.0-0.60.8-1.20.10.60.5-0.8-1.00.51.2-0.8-1.0-1.2-0.9
Extinction: sum of active levers before priming0.40.40.9-0.2-0.20.31.0-0.7-0.50.50.90.1-1.00.7-0.50.8-0.90.2-0.2-0.40.9-0.60.80.3-0.7-0.8-0.2
Active lever presses in extinction session 61.11.13.51.00.8-0.8-0.3-0.6-0.80.3-1.9-1.50.60.8-0.80.80.21.2-1.4-1.10.8-1.01.31.1-1.3-1.3-1.2
Bone: final force0.61.02.1-0.4-0.20.5-1.30.60.9-0.6-0.50.41.2-1.41.1-1.21.3-1.01.00.9-1.31.4-1.1-1.01.01.10.7
Bone: final moment0.61.02.2-0.7-0.40.7-1.20.41.1-0.4-0.30.61.4-1.41.0-1.11.3-1.10.91.0-1.21.5-1.1-0.91.01.10.8
Food consumed during 24 hour testing period0.20.20.5-0.7-0.60.70.3-0.30.70.30.50.7-0.1-0.0-0.10.50.1-0.5-0.30.40.60.1-0.20.00.20.20.4
Glucose1.42.18.4-1.3-1.11.1-2.20.01.90.0-2.00.32.9-1.91.0-1.32.7-1.30.41.0-1.81.8-0.6-0.60.50.60.6
Heart weight2.12.99.53.12.9-2.8-0.90.9-2.7-0.8-1.4-2.51.00.20.1-1.7-1.22.20.2-1.9-1.8-0.41.40.1-1.3-1.3-1.9
Delay discount hyperbolic model param1.21.33.51.81.9-1.9-1.31.3-1.4-1.4-0.6-1.2-1.0-0.60.7-1.10.00.60.4-0.8-1.00.41.3-0.7-1.0-1.3-1.0
Intermittent access intake day 1-15 change1.21.24.3-2.1-2.01.80.8-1.41.11.21.61.60.6-0.2-0.3-0.7-0.2-0.71.00.8-1.40.5-0.8-0.00.80.80.6
Intermittent access intake escalation1.11.03.3-1.8-1.71.60.2-0.91.20.71.11.40.9-0.60.2-0.70.3-0.91.21.0-1.30.8-0.8-0.40.90.90.8
Intermittent access intake escalation 21.91.96.6-2.6-2.52.50.8-0.91.90.91.42.00.4-0.40.10.30.6-1.50.91.50.00.6-1.3-0.31.31.31.5
Intermitt. access day 1 inactive lever presses0.80.83.4-0.9-0.81.0-0.1-1.40.51.3-1.5-0.41.80.5-1.00.70.40.5-1.3-0.20.3-0.60.41.3-0.6-0.5-0.8
Intermitt. access day 15 inactive lever presses0.10.10.3-0.2-0.20.0-0.0-0.6-0.30.3-0.1-0.2-0.30.1-0.20.1-0.00.10.1-0.2-0.1-0.20.40.2-0.5-0.5-0.4
Intermitt. access escalation Index0.60.51.8-0.8-0.80.6-0.60.50.8-0.4-0.50.5-0.0-0.70.7-0.41.3-1.00.80.8-0.60.6-0.9-0.61.00.80.8
Intermittent access day 1 total infusions1.31.53.6-0.8-0.80.71.8-1.70.21.60.90.30.01.6-1.81.9-1.20.6-1.6-0.61.8-1.50.91.6-0.9-0.9-0.5
Intermittent access day 15 total infusions1.41.54.9-2.0-2.01.81.8-2.21.11.91.51.30.71.1-1.41.2-0.7-0.2-0.70.30.8-0.80.11.2-0.1-0.00.2
Intermittent access terminal intake (last 3 days)1.82.06.9-2.6-2.62.51.7-2.01.71.91.91.90.40.7-1.11.1-0.4-0.7-0.40.90.7-0.3-0.40.80.40.40.7
Intermittent access total infusions1.61.84.4-2.1-2.02.01.9-2.01.22.01.51.3-0.31.3-1.71.6-0.7-0.2-1.20.31.2-1.10.21.4-0.2-0.10.1
Intermittent access day 1 locomotion0.20.21.0-0.3-0.30.50.20.00.6-0.20.40.5-0.50.00.00.70.3-0.5-0.40.51.00.0-0.4-0.10.40.40.5
Intermittent access day 15 total locomotion0.30.31.1-1.0-1.00.90.4-1.00.61.00.40.50.80.2-0.50.2-0.1-0.1-0.10.4-0.2-0.10.10.5-0.1-0.1-0.0
Intermittent access total locomotion0.70.82.1-1.1-1.11.3-0.00.21.3-0.30.81.3-1.1-0.60.50.00.8-1.30.31.50.20.6-1.1-0.61.21.01.1
Intermittent access standard deviation2.02.17.3-2.7-2.72.71.7-2.41.62.21.51.70.20.8-1.31.0-0.4-0.6-0.40.90.4-0.6-0.51.10.50.50.5
Left kidney weight2.46.716.1-1.1-1.11.3-2.52.42.5-2.4-1.21.40.8-3.13.3-1.44.0-3.32.93.1-0.92.9-3.3-2.93.33.33.3
Right kidney weight1.43.99.6-1.5-1.51.6-1.61.22.2-1.3-0.91.31.0-2.22.3-0.83.1-2.62.42.3-0.52.0-2.4-1.92.52.42.6
Cocaine induced anxiety2.32.77.82.01.9-1.8-2.82.7-0.7-2.7-2.2-1.2-0.9-1.92.3-1.51.7-0.51.30.5-0.81.4-0.4-1.80.60.30.3
Post-drug Anxiety1.51.74.71.21.1-1.1-2.22.0-0.2-1.9-1.5-0.70.0-1.71.9-1.51.3-0.81.60.8-1.21.5-0.8-1.61.10.80.4
Baseline Anxiety1.51.65.9-1.3-1.21.01.6-2.30.22.40.50.21.51.5-1.91.0-1.10.6-1.2-0.60.3-1.30.71.8-0.8-0.7-0.9
Tail length0.72.15.4-1.0-1.00.71.4-2.00.62.1-0.6-0.22.31.6-1.82.2-0.30.7-2.2-1.02.0-1.61.12.0-1.3-1.1-0.4
Length with tail0.62.016.0-2.0-1.91.9-0.4-1.12.31.1-1.50.64.0-0.5-0.00.72.1-1.0-0.60.80.40.5-1.00.50.81.01.1
Length without tail1.22.710.1-0.7-0.71.0-2.20.61.5-0.6-1.90.13.2-2.01.6-1.72.7-1.21.41.3-2.11.9-1.7-1.11.61.71.0
Times rat made contact with spout0.40.52.4-0.0-0.2-0.0-0.2-0.50.30.5-1.6-0.60.60.5-0.51.20.80.2-1.3-0.31.2-0.70.60.9-0.6-0.6-0.3
Lifetime Intake1.61.84.2-1.9-1.91.82.0-2.00.92.01.61.1-0.41.4-1.71.7-0.9-0.0-1.20.11.4-1.20.41.4-0.4-0.4-0.0
Liver weight, left0.60.92.60.10.0-0.4-0.5-1.1-0.31.2-1.5-1.01.50.4-1.0-0.00.21.0-1.2-0.9-0.6-0.61.11.2-1.2-1.2-1.6
Liver weight, right1.83.010.3-3.0-3.23.10.3-1.53.11.5-0.22.01.6-0.3-0.31.42.0-1.9-0.61.81.20.4-1.40.51.21.31.6
Locomotor activity0.71.03.71.31.2-1.1-1.91.4-0.3-1.5-1.5-0.91.1-1.31.2-1.10.90.10.6-0.1-1.01.20.0-0.90.0-0.0-0.2
Locomotor testing distance1.42.36.61.61.4-1.2-2.62.3-0.3-2.3-1.2-0.60.8-2.22.1-2.01.2-0.41.50.5-1.72.1-0.6-1.90.70.60.3
Locomotor testing rearing0.91.43.60.50.4-0.2-1.41.60.4-1.50.10.40.7-1.81.7-1.50.7-0.81.70.9-1.21.9-1.1-1.71.21.21.0
Locomotion in novel chamber0.50.63.01.51.7-1.5-0.41.0-1.1-1.1-0.3-0.90.1-0.10.5-0.2-0.50.50.2-0.90.20.10.1-0.4-0.0-0.0-0.3
Locomotion in novel chamber post-restriction0.40.52.0-0.2-0.20.20.40.40.4-0.30.80.7-0.1-0.30.50.5-0.2-0.50.80.40.90.4-1.4-0.61.31.41.0
Fecal boli incidents, locomotor time 10.60.71.7-1.3-1.31.31.1-1.30.71.10.60.7-0.90.8-0.81.1-0.3-0.4-0.50.11.1-0.70.40.7-0.4-0.40.3
Change in fecal boli incidents, locomotor task0.50.51.40.40.4-0.40.8-0.4-0.50.60.1-0.40.80.9-0.90.8-1.00.9-1.2-0.90.8-0.80.20.8-0.5-0.2-0.6
Time >=10cm from walls, locomotor time 10.20.20.50.1-0.00.1-0.40.70.3-0.50.50.4-0.6-0.60.4-0.5-0.1-0.40.00.5-0.20.7-0.3-0.60.30.30.2
Bouts of movement, locomotor time 12.73.08.7-2.2-2.12.12.9-2.31.12.52.21.7-0.01.8-2.12.4-1.6-0.0-1.7-0.22.1-1.40.11.7-0.3-0.20.3
Total resting periods, locomotor time 12.83.18.5-2.2-2.12.12.9-2.41.22.61.81.50.22.0-2.12.6-1.4-0.0-1.9-0.32.3-1.60.41.8-0.5-0.40.3
Rest time, locomotor task time 10.40.40.90.50.7-0.60.3-0.2-1.00.0-0.4-0.8-0.90.7-0.30.5-0.30.6-0.3-0.80.5-0.90.70.4-0.9-0.8-0.6
Distance moved, locomotor task time 10.60.73.3-0.9-1.21.0-0.3-0.21.40.3-0.20.81.8-0.70.2-0.00.8-0.60.41.0-0.10.8-0.9-0.21.11.00.8
Vertical activity count, locomotor time 10.60.62.11.31.1-1.2-1.21.2-0.4-1.0-0.7-0.61.4-0.80.7-1.00.00.40.3-0.2-0.90.8-0.0-0.60.30.1-0.3
Time >=10cm from walls, locomotor time 20.70.83.91.01.0-1.1-1.40.4-0.5-0.3-1.6-1.22.0-0.50.1-0.90.40.7-0.4-0.6-1.10.40.50.1-0.4-0.5-1.1
Bouts of movement, locomotor time 23.63.912.7-1.9-1.82.03.6-2.20.72.32.61.6-1.42.4-2.23.1-2.10.0-2.2-0.43.1-2.10.41.8-0.5-0.50.4
Total resting periods, locomotor time 23.33.611.2-1.9-1.82.03.3-2.00.82.12.61.7-1.62.2-2.02.9-2.0-0.2-2.1-0.23.0-1.90.31.6-0.5-0.40.4
Rest time, locomotor task time 20.60.71.4-0.8-0.50.6-0.40.60.5-0.61.00.9-1.1-1.01.0-1.00.5-1.21.10.8-0.91.1-0.7-1.20.50.50.9
Distance moved, locomotor task time 20.30.42.80.60.3-0.50.3-0.5-0.30.5-0.4-0.51.70.5-0.60.5-0.71.0-0.4-0.50.3-0.40.20.70.0-0.1-0.6
Vertical activity count, locomotor time 21.01.13.41.71.5-1.7-1.20.4-0.9-0.3-1.8-1.71.8-0.1-0.2-0.5-0.11.3-0.6-0.9-0.6-0.00.50.5-0.4-0.5-1.4
Light reinforcement 10.40.71.71.31.2-1.30.10.0-1.2-0.2-0.4-1.0-0.10.6-0.50.4-0.81.0-0.7-1.20.6-0.71.00.5-1.0-1.0-1.0
Light reinforcement 20.81.15.30.70.7-0.61.1-0.6-0.70.4-0.5-0.7-0.21.4-1.12.0-0.81.1-1.3-0.72.3-1.50.41.2-0.5-0.4-0.6
Bone: marrow area0.81.75.8-2.1-2.12.40.9-0.81.80.91.21.81.1-0.30.20.40.5-1.40.71.40.20.5-1.5-0.31.51.51.7
Bone: maximum diameter0.50.95.30.20.2-0.4-0.8-0.8-0.40.9-2.1-1.32.30.1-0.4-0.80.51.0-0.2-0.6-1.5-0.30.60.8-0.6-0.6-1.1
Bone: maximum force0.20.31.1-0.3-0.00.4-0.70.10.3-0.1-0.40.01.0-0.70.5-0.90.7-0.40.60.3-1.00.7-0.5-0.40.40.40.2
Bone: maximum moment0.20.31.3-0.6-0.30.6-0.5-0.10.60.1-0.10.31.1-0.60.4-0.60.6-0.50.50.4-0.90.7-0.5-0.30.40.50.2
Mean time between licks in bursts1.01.48.1-1.2-1.41.12.4-1.20.51.22.81.7-0.91.0-0.80.7-1.9-0.20.00.40.6-0.6-0.80.30.80.90.8
Mean num. licks in bursts0.30.31.90.40.5-0.5-0.51.0-0.1-1.00.40.1-1.4-0.60.7-0.40.1-0.50.20.10.00.6-0.0-0.80.10.00.3
Cd content in liver2.42.68.22.62.7-2.9-0.21.1-2.8-1.40.8-1.5-2.20.20.4-1.8-1.91.41.0-1.5-1.7-0.31.4-0.7-1.2-1.3-1.3
Co content in liver1.41.74.41.41.4-1.3-1.62.1-0.9-2.1-0.1-0.4-1.6-1.41.7-1.90.5-0.41.60.6-1.61.2-0.6-1.70.70.60.1
Cu content in liver0.60.71.9-1.0-1.01.40.10.01.3-0.10.21.00.4-0.40.40.60.9-0.90.41.20.80.5-1.0-0.41.01.11.2
Fe content in liver0.60.82.41.51.4-1.6-1.11.1-1.0-1.0-0.8-1.00.4-0.60.7-1.3-0.10.70.6-0.3-1.20.5-0.0-0.60.10.1-0.5
K content in liver1.31.33.8-1.8-2.01.91.1-1.11.61.20.41.40.90.4-0.51.30.4-0.7-0.21.21.2-0.2-1.10.51.11.11.1
Mg content in liver1.61.74.3-2.0-2.11.91.6-1.91.41.90.21.11.21.0-1.31.90.1-0.2-1.10.51.7-0.9-0.31.30.30.30.5
Mn content in liver1.11.32.30.80.8-0.80.7-0.6-1.10.7-0.9-1.30.61.4-1.21.1-0.81.5-1.3-1.41.1-1.51.51.4-1.4-1.4-1.2
Na content in liver1.71.85.2-0.3-0.50.42.3-1.8-0.61.80.5-0.20.32.1-1.81.8-1.71.3-1.2-0.91.6-2.00.51.8-0.5-0.5-0.7
Rb content in liver0.60.73.5-0.7-0.80.81.6-0.80.11.01.90.9-0.80.9-0.90.9-1.50.3-0.5-0.10.8-0.60.30.5-0.2-0.30.0
Se content in liver0.40.41.5-0.5-0.60.20.10.20.6-0.21.21.1-0.1-0.60.4-0.6-0.3-0.70.70.8-0.50.9-0.8-0.70.80.80.7
Sr content in liver1.51.45.8-1.1-1.11.11.6-0.00.70.02.41.8-1.90.30.20.9-0.7-1.10.61.41.3-0.1-1.2-0.51.31.21.6
Zn content in liver0.40.41.60.40.5-0.50.8-0.1-0.70.1-0.2-0.5-0.71.0-0.51.0-0.50.6-0.4-0.51.3-1.10.30.6-0.3-0.3-0.2
Bone: minimum diameter0.20.42.9-0.9-0.70.90.4-1.10.31.1-0.7-0.11.70.4-0.40.10.20.20.1-0.1-0.4-0.4-0.20.60.20.20.1
Time in familiar zone, hab. session 12.11.95.0-0.3-0.50.4-0.41.50.7-1.51.31.4-1.1-1.51.8-1.30.5-1.52.21.4-1.01.6-1.7-2.01.81.71.8
Time in novel zone, hab. session 11.91.95.4-0.3-0.10.20.5-1.8-0.21.8-1.4-1.01.31.5-1.91.5-0.21.2-2.3-1.01.1-1.61.42.1-1.6-1.5-1.6
Total zone transitions, hab. session 10.91.25.41.41.5-1.4-1.00.3-1.0-0.3-2.3-2.01.90.2-0.10.20.61.2-0.6-1.00.1-0.60.80.7-0.8-0.7-1.1
Total locomotion distance, hab. session 10.40.52.50.60.4-0.7-0.1-0.3-0.40.4-0.9-0.81.60.5-0.70.7-0.31.0-1.1-0.60.6-0.60.70.8-0.7-0.7-0.8
Locomotion velocity, hab. session 10.60.81.70.90.8-1.00.1-0.2-0.80.3-0.9-1.11.10.8-0.80.8-0.61.3-1.2-0.90.8-0.91.00.9-0.9-1.0-1.1
Time in familiar zone, hab. session 21.31.44.1-1.5-1.41.21.4-2.00.82.00.60.60.41.2-1.71.3-0.60.2-1.6-0.50.9-1.00.91.5-1.0-0.9-0.5
Time in novel zone, hab. session 21.01.02.91.11.0-0.7-1.01.7-0.4-1.7-0.4-0.3-0.2-1.01.5-1.00.6-0.31.40.7-0.60.9-0.9-1.31.01.00.7
Total zone transitions, hab. session 20.30.43.60.30.3-0.4-0.1-0.30.00.3-1.0-0.71.90.3-0.40.70.30.6-0.7-0.60.7-0.40.40.6-0.4-0.3-0.3
Total locomotion distance, hab. session 20.50.63.00.30.1-0.40.1-0.40.00.4-1.1-0.61.70.6-0.71.20.10.8-1.3-0.61.2-0.60.70.9-0.7-0.7-0.5
Locomotion velocity, hab. session 20.50.62.00.50.3-0.6-0.0-0.3-0.20.3-1.2-0.81.40.6-0.61.20.10.9-1.3-0.61.2-0.70.80.9-0.8-0.8-0.6
Novel to familiar place preference ratio0.20.20.6-0.7-0.60.60.2-0.60.30.60.80.5-0.0-0.1-0.2-0.5-0.2-0.30.20.2-0.70.20.10.0-0.1-0.1-0.0
Novelty place preference0.40.41.4-1.2-1.11.10.3-0.80.90.80.90.90.3-0.2-0.2-0.30.0-0.60.20.5-0.60.3-0.30.00.20.30.3
Time in novel zone, NPP test0.60.62.2-1.5-1.31.40.7-1.20.91.21.11.00.40.1-0.5-0.2-0.2-0.50.10.4-0.60.1-0.10.30.10.10.3
Total zone transitions, NPP test1.21.85.50.70.7-0.8-0.0-0.9-0.70.8-2.3-1.81.91.3-1.11.50.51.4-1.7-1.41.4-1.61.31.7-1.4-1.3-1.2
Total locomotion distance, NPP test1.11.64.30.50.4-0.50.5-0.9-0.30.9-1.6-1.22.11.3-1.31.8-0.11.3-2.0-1.11.8-1.51.11.7-1.2-1.1-0.9
Locomotion velocity, NPP test0.81.13.50.80.7-0.70.0-0.3-0.40.3-1.7-1.21.90.9-0.81.50.21.1-1.6-0.81.7-1.10.81.2-0.9-0.8-0.7
Intraocular pressure0.60.86.2-0.7-0.70.31.0-1.60.31.60.30.12.50.8-1.20.7-0.80.5-0.6-0.40.3-0.50.11.1-0.2-0.1-0.5
Delta distance traveled before/after self-admin2.42.55.8-1.7-1.61.7-0.10.91.8-0.91.32.0-1.3-1.31.4-0.21.4-2.31.52.00.21.4-2.0-1.62.12.02.4
Delta ambulatory time before/after self-admin1.71.93.9-1.9-1.81.80.20.21.8-0.31.42.0-0.9-0.90.9-0.21.0-1.91.11.70.01.1-1.7-1.11.71.71.9
Parametrial fat weight0.81.55.7-2.2-2.42.01.1-1.91.51.80.51.22.10.4-0.70.50.3-0.5-0.00.6-0.1-0.2-0.80.70.70.80.7
Pavlov. Cond. lever latency0.40.53.50.40.5-0.3-1.10.5-0.2-0.5-0.3-0.30.5-0.90.7-1.60.3-0.10.70.2-1.90.90.0-0.7-0.0-0.0-0.3
Pavlov. Cond. magazine entry latency0.40.62.1-0.8-0.90.90.5-0.91.00.8-0.40.41.20.4-0.71.40.3-0.1-1.10.11.4-0.3-0.20.80.10.20.3
Pavlov. Cond. change in total contacts0.20.21.0-0.5-0.60.4-0.1-0.10.60.1-0.70.11.0-0.10.00.60.9-0.4-0.10.30.60.0-0.40.10.40.40.4
Pavlov. Cond. index score0.50.63.1-0.6-0.80.70.6-0.80.70.7-0.60.20.60.7-0.71.60.5-0.0-1.10.01.8-0.7-0.10.90.00.00.2
Pavlov. Cond. latency score0.40.53.1-0.7-0.90.70.6-0.70.80.6-0.40.40.20.6-0.61.60.5-0.2-0.90.11.7-0.7-0.10.70.10.10.4
Pavlov. Cond. lever contacts0.80.94.4-0.8-1.00.91.5-1.10.51.00.50.6-0.31.2-1.01.9-0.40.0-1.1-0.12.1-1.1-0.01.0-0.0-0.00.3
Pavlov. Cond. magazine entry number0.50.72.31.01.2-1.2-0.20.7-1.4-0.60.3-0.8-1.50.00.3-1.2-0.80.50.7-0.6-1.2-0.10.7-0.4-0.6-0.7-0.7
Pavlov. Cond. intertrial magazine entries0.40.51.41.11.1-1.0-0.60.4-0.6-0.3-0.9-1.11.20.0-0.1-0.0-0.10.9-0.7-0.80.1-0.10.80.3-0.9-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.73.1-0.6-0.80.70.7-1.00.60.9-0.60.10.70.8-0.91.70.40.1-1.2-0.11.8-0.90.11.0-0.1-0.10.1
Pavlov. Cond. response bias0.60.73.4-0.9-1.11.10.8-0.81.10.7-0.20.71.00.5-0.61.70.5-0.3-0.90.41.9-0.4-0.60.70.50.60.7
Pavlov. Cond. lever latency2.83.76.7-0.7-0.60.9-1.41.91.5-1.80.81.6-0.3-2.42.4-1.61.7-2.32.42.6-1.22.4-2.6-2.52.62.62.3
Pavlov. Cond. magazine entry latency0.60.72.1-0.9-1.10.81.0-1.40.61.30.10.30.80.9-1.21.2-0.40.3-1.1-0.31.0-0.80.41.1-0.4-0.4-0.3
Pavlov. Cond. change in total contacts2.53.46.7-0.2-0.3-0.02.2-2.6-1.02.30.3-0.7-0.32.5-2.61.8-2.11.8-2.2-2.11.5-2.42.12.4-2.1-2.1-1.8
Pavlov. Cond. index score1.72.24.2-0.1-0.3-0.11.5-1.9-0.61.8-0.1-0.60.31.9-2.11.6-1.31.5-2.0-1.71.3-1.81.72.0-1.8-1.7-1.5
Pavlov. Cond. latency score1.61.94.0-0.4-0.50.21.5-2.0-0.31.8-0.1-0.40.21.8-2.01.7-1.11.2-1.9-1.51.4-1.81.52.0-1.6-1.6-1.3
Pavlov. Cond. lever contacts2.73.77.11.21.2-1.40.8-1.4-1.81.3-1.4-2.10.32.1-2.11.4-1.32.4-2.4-2.71.1-2.32.62.3-2.6-2.6-2.5
Pavlov. Cond. magazine entry number0.91.13.11.21.3-1.1-1.31.8-0.7-1.6-0.2-0.5-0.6-1.21.4-1.70.4-0.21.40.4-1.51.1-0.4-1.40.50.50.2
Pavlov. Cond. intertrial magazine entries0.40.51.71.21.2-1.1-0.50.6-1.3-0.6-0.7-1.10.00.00.4-1.0-0.20.80.7-0.5-1.1-0.20.3-0.2-0.2-0.3-0.6
Pavlov. Cond. lever-magazine prob. diff.1.72.14.3-0.2-0.40.01.5-2.0-0.41.8-0.2-0.60.41.9-2.11.8-1.21.4-2.1-1.61.5-1.91.62.1-1.6-1.6-1.4
Pavlov. Cond. response bias2.12.85.00.80.7-1.01.1-1.5-1.41.4-0.8-1.50.52.0-2.11.4-1.42.1-2.2-2.21.1-2.12.22.1-2.2-2.2-2.1
Time in closed arm before self-admin0.30.31.2-0.9-0.91.00.4-0.50.70.8-0.40.20.60.3-0.31.00.4-0.2-0.20.31.1-0.3-0.20.40.10.10.4
Time in closed arm after self-admin0.50.52.20.30.1-0.21.5-0.0-0.50.00.70.1-1.01.0-0.21.2-1.00.40.5-0.41.5-1.0-0.40.20.40.50.6
Time in open arm before self-admin0.60.72.31.20.9-1.1-0.90.1-0.4-0.3-1.5-1.00.9-0.0-0.2-0.10.40.8-1.0-0.6-0.2-0.11.30.4-1.0-1.2-0.9
Time in open arm after self-admin0.40.51.5-0.8-0.70.70.5-1.20.41.10.30.4-0.10.5-1.00.5-0.20.1-1.10.00.2-0.40.70.8-0.7-0.8-0.6
Bone: periosteal estimation0.30.64.3-1.1-1.01.1-0.2-0.60.80.6-0.60.32.1-0.40.3-0.50.9-0.50.80.6-0.90.4-0.8-0.10.80.80.6
Bone: periosteal perimeter0.40.74.6-0.6-0.60.5-0.8-0.70.50.6-2.0-0.52.1-0.30.2-0.51.5-0.00.50.3-1.00.1-0.40.30.40.40.1
Bone: post-yield work0.91.33.8-0.5-0.30.51.9-1.6-0.41.60.9-0.00.11.7-1.51.3-1.60.9-1.0-1.01.1-1.60.81.4-0.8-0.7-0.5
Progressive ratio test 1 active lever presses0.80.82.8-1.3-1.31.31.3-1.11.01.01.71.3-0.10.5-0.81.1-0.6-0.5-0.70.61.2-0.2-0.10.50.00.10.5
Progressive ratio test 1 breakpoint0.80.82.7-1.2-1.21.11.3-1.30.71.21.61.00.10.7-1.01.0-0.9-0.2-0.80.31.0-0.30.20.7-0.3-0.20.1
Progressive ratio test 1 inactive lever presses1.11.23.1-1.0-0.90.90.9-1.80.31.7-0.1-0.01.11.1-1.61.2-0.60.6-1.5-0.60.7-1.01.11.6-1.1-1.2-0.9
Progressive ratio test 2 active lever presses2.32.48.3-2.6-2.72.52.1-1.31.81.42.92.5-0.50.5-0.71.0-0.6-1.20.11.40.8-0.1-1.10.21.01.11.5
Progressive ratio test 2 breakpoint2.42.79.6-2.7-2.72.62.5-1.61.81.63.12.6-0.90.8-1.01.1-0.8-1.1-0.11.30.9-0.4-1.00.51.01.11.4
Progressive ratio test 2 inactive lever presses1.41.67.3-2.7-2.62.41.0-1.61.71.61.61.8-0.10.1-0.80.3-0.0-1.0-0.11.1-0.20.1-0.40.40.40.40.6
Incentive Sensitization - Responses1.71.75.5-2.3-2.32.21.9-1.31.51.52.22.00.00.7-0.90.8-0.5-0.7-0.20.90.5-0.4-0.70.60.60.81.0
Incentive Sensitization - Breakpoint1.51.65.2-2.2-2.32.11.8-1.31.51.52.01.90.10.7-0.90.8-0.4-0.7-0.20.80.4-0.4-0.70.60.60.70.9
Sum of active levers in priming session hrs 5-60.80.82.00.70.6-0.70.0-0.3-0.70.2-1.1-1.0-0.10.8-0.71.0-0.21.0-1.3-0.91.1-1.01.40.9-1.3-1.4-1.0
Progressive ratio0.20.30.70.80.8-0.8-0.10.5-0.8-0.3-0.1-0.5-0.50.2-0.1-0.4-0.60.5-0.4-0.5-0.3-0.20.80.0-0.7-0.8-0.6
Food seeking constrained by brief footshock0.60.71.90.50.5-0.80.6-0.7-0.80.60.0-0.60.00.9-1.00.3-1.01.0-1.0-0.90.2-0.91.40.9-1.4-1.3-1.1
Seeking ratio, punishment vs. effort0.40.51.8-0.7-0.70.41.0-1.30.31.10.30.20.60.9-0.91.1-0.30.3-0.7-0.21.0-0.90.20.9-0.3-0.2-0.1
Retroperitoneal fat weight3.611.931.7-5.5-5.65.40.7-1.75.31.71.44.43.5-1.81.00.32.9-3.92.14.2-0.22.2-4.2-1.04.14.24.2
Reaction time number correct1.21.73.0-1.6-1.41.6-0.70.11.5-0.10.61.4-0.3-1.41.0-1.41.2-1.71.41.6-1.61.5-1.5-1.11.41.51.2
Reaction time mean minus median0.20.20.9-0.5-0.60.40.4-0.00.8-0.20.80.90.0-0.30.10.4-0.1-0.6-0.10.40.70.5-0.3-0.30.30.40.7
Reaction time mean minus median AUC0.50.71.9-1.0-1.10.90.40.11.3-0.41.01.4-0.3-0.50.50.80.5-1.20.20.81.20.6-0.7-0.60.70.71.4
Reaction time num false alarms1.72.34.40.40.5-0.51.2-1.6-0.81.5-0.9-1.21.12.0-1.91.7-1.11.6-2.1-1.81.6-2.01.82.1-1.8-1.8-1.4
Reaction time num false alarms AUC1.42.03.81.11.2-1.20.6-0.9-1.30.9-1.1-1.61.21.5-1.41.0-1.01.8-1.7-1.90.9-1.61.81.6-1.9-1.8-1.6
Reaction time trials correct on left1.21.73.0-1.6-1.41.6-0.70.11.5-0.10.61.4-0.3-1.41.0-1.41.2-1.71.41.6-1.61.5-1.5-1.11.41.51.2
Reaction time trials on left1.21.73.0-1.7-1.51.6-0.60.11.5-0.10.71.4-0.3-1.41.0-1.41.1-1.71.41.6-1.61.5-1.5-1.11.41.51.3
Reaction time mean0.40.61.4-0.3-0.50.5-0.10.60.8-0.80.81.0-0.3-0.80.8-0.10.4-1.00.60.80.30.9-0.9-0.91.01.01.2
Reaction time mean AUC0.30.41.3-0.3-0.50.50.30.50.7-0.61.11.0-0.6-0.40.60.20.0-0.80.50.70.70.6-0.8-0.70.80.81.1
Median of all reaction times0.60.81.7-0.3-0.40.5-0.50.90.9-1.00.60.9-0.3-1.11.1-0.40.7-1.20.91.1-0.11.2-1.2-1.21.21.21.3
Reaction time omissions0.81.15.7-1.1-1.31.10.9-0.21.10.12.41.80.1-0.60.4-0.3-0.7-1.01.10.9-0.31.1-1.1-0.81.11.21.3
Reaction time false alarm rate2.94.06.91.61.5-1.61.3-1.3-1.81.3-1.0-2.01.32.3-2.11.9-1.92.5-2.5-2.61.8-2.42.52.3-2.5-2.4-2.1
Reaction time premature initiation rate1.21.59.61.41.4-1.6-2.41.2-0.3-1.4-3.1-1.70.9-1.00.9-0.22.00.2-0.4-0.40.10.50.4-0.3-0.4-0.5-0.6
Reaction time premature initiations1.31.88.30.60.6-0.7-2.91.40.5-1.6-2.7-0.90.7-1.81.6-1.22.7-0.80.60.6-0.91.4-0.5-1.00.40.40.2
Std. dev. reaction times0.40.62.0-0.9-1.00.91.0-0.31.10.11.41.30.00.00.00.8-0.2-0.8-0.00.61.10.3-0.7-0.20.70.81.2
Reaction time trials completed1.21.73.0-1.7-1.51.6-0.60.11.5-0.10.71.4-0.3-1.41.0-1.41.1-1.71.41.6-1.61.5-1.5-1.11.41.51.3
Reaction time trials AUC1.11.52.8-1.7-1.51.7-0.50.01.50.00.71.4-0.4-1.20.9-1.31.1-1.71.41.5-1.41.3-1.4-1.01.31.31.2
Run reversals in cocaine runway, females2.12.14.0-0.7-0.70.8-0.81.21.2-1.31.21.4-0.5-1.71.7-1.40.7-1.71.91.5-1.21.9-1.9-1.81.72.01.7
Run reversals in cocaine runway, males0.20.20.60.70.6-0.7-0.80.7-0.1-0.6-0.4-0.30.6-0.60.4-0.60.10.20.10.0-0.60.6-0.0-0.4-0.00.0-0.1
Latency to leave start box in cocaine runway0.30.31.41.00.9-0.70.30.2-1.2-0.4-0.3-0.9-1.00.70.00.3-0.20.60.3-0.20.6-0.90.20.1-0.2-0.2-0.3
Latency to leave start box in cocaine runway, F1.31.44.72.22.0-1.9-1.21.6-1.7-1.7-0.8-1.4-1.4-0.41.1-1.10.30.51.1-0.3-0.70.10.3-0.9-0.2-0.3-0.5
Latency to leave start box in cocaine runway, M1.41.45.1-0.8-0.81.02.2-1.60.01.50.90.3-0.31.8-1.51.8-1.20.5-0.9-0.51.7-1.8-0.11.40.00.20.1
Std. dev. time between licks in bursts1.61.97.8-0.9-1.00.92.8-1.80.21.81.30.60.02.1-1.72.2-1.60.6-1.2-0.32.1-1.9-0.11.60.00.20.2
Total sessions with >9 infusions0.80.82.8-1.5-1.61.70.8-1.01.40.70.71.2-0.50.3-0.41.00.4-0.8-0.41.01.1-0.2-0.50.40.50.60.9
Short access day 1 total inactive lever presses0.50.51.5-1.2-1.21.20.4-1.01.01.10.00.50.60.4-1.00.50.1-0.0-1.10.10.1-0.30.50.9-0.5-0.5-0.3
Short access day 10 total inactive lever presses0.30.31.9-0.7-0.60.6-0.9-0.10.60.1-1.4-0.11.0-0.50.2-0.31.1-0.30.20.3-0.70.4-0.30.00.20.2-0.1
Short access day 1 total infusions0.80.82.7-1.6-1.61.60.8-0.91.50.90.61.10.20.3-0.41.00.4-0.9-0.40.81.1-0.2-0.40.40.50.40.9
Short access day 10 total infusions1.41.63.6-1.3-1.31.21.6-1.90.61.80.80.6-0.61.5-1.81.9-0.90.4-1.8-0.01.7-1.40.81.6-0.8-0.9-0.5
Short access total infusions1.41.53.5-1.5-1.61.51.9-1.70.81.71.41.0-1.01.4-1.51.8-0.9-0.0-1.10.21.7-1.20.41.2-0.4-0.40.0
Short access day 1 locomotion1.82.05.8-2.4-2.42.31.3-1.72.11.41.31.8-0.40.5-0.91.60.3-1.2-1.01.11.6-0.2-1.10.70.91.01.0
Short access day 10 total locomotion2.22.56.4-1.6-1.61.9-1.30.82.1-0.9-0.61.4-0.6-1.61.3-0.12.5-2.20.82.50.21.4-2.0-1.22.11.91.8
Short access total locomotion1.01.12.7-1.2-1.21.40.10.01.4-0.30.71.4-1.2-0.50.50.60.9-1.40.31.61.00.5-1.4-0.61.31.41.4
One hour access (0.3 mA shock)2.93.412.6-3.5-3.43.32.2-2.62.12.52.62.5-0.00.8-1.41.1-0.6-1.1-0.41.10.5-0.4-0.81.00.70.70.9
Compulsive drug intake0.30.31.00.81.0-0.9-0.20.5-1.0-0.4-0.3-0.8-0.20.10.1-0.7-0.30.50.2-0.8-0.9-0.20.5-0.1-0.3-0.5-0.5
One hour access (shock baseline)1.71.97.1-2.7-2.72.51.5-1.91.81.81.81.90.10.5-1.01.1-0.2-0.9-0.21.10.7-0.2-0.60.70.50.60.8
Social response proportion6.77.216.7-2.7-2.93.2-0.50.93.8-0.71.13.21.1-2.32.0-0.02.7-3.41.93.80.32.5-4.1-2.03.94.13.8
Social responses2.63.46.8-1.9-1.91.9-0.60.62.3-0.40.92.11.4-1.91.5-1.11.6-2.22.02.2-1.22.2-2.6-1.62.62.62.2
Social time3.14.17.2-1.6-1.51.5-1.11.52.3-1.41.42.3-0.8-2.42.1-1.51.7-2.72.32.5-1.32.6-2.6-2.32.62.62.5
Soleus weight1.23.49.1-2.0-2.12.3-1.20.12.9-0.1-1.11.52.0-1.71.30.03.0-2.31.02.30.01.7-2.4-0.92.32.32.2
Bone: stiffness0.10.21.40.30.3-0.2-0.50.4-0.5-0.3-0.2-0.3-0.2-0.40.5-1.00.20.01.00.0-1.20.3-0.1-0.50.20.1-0.1
Tibialis anterior weight0.41.53.1-0.1-0.00.01.0-1.7-0.51.6-0.7-0.90.71.6-1.61.5-0.61.2-1.4-1.11.2-1.71.31.8-1.3-1.3-1.2
Time to tail flick, vehicle, before self-admin0.30.31.3-0.8-0.90.8-0.6-0.40.70.4-0.20.4-0.4-0.60.1-0.80.7-0.40.10.6-1.10.6-0.6-0.10.60.5-0.0
Time to tail flick, vehicle, after self-admin0.30.35.20.20.1-0.0-0.60.2-0.4-0.3-0.2-0.2-2.3-0.20.3-0.70.4-0.20.10.2-0.60.00.0-0.30.2-0.2-0.4
Time to tail flick, test, before self-admin0.20.20.60.20.2-0.2-0.30.50.2-0.6-0.4-0.0-0.8-0.30.50.20.7-0.40.20.30.50.1-0.4-0.40.40.40.6
Time to tail flick, test, after self-admin0.10.10.3-0.2-0.2-0.00.4-0.6-0.10.5-0.2-0.10.00.5-0.40.4-0.20.3-0.2-0.30.3-0.50.30.5-0.2-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.20.21.00.60.5-0.40.00.2-0.6-0.30.6-0.1-1.00.00.1-0.4-0.50.10.2-0.2-0.30.00.4-0.3-0.2-0.4-0.3
Delta time to tail flick, test, before/after SA0.10.10.2-0.2-0.30.30.1-0.4-0.20.5-0.1-0.10.20.1-0.2-0.2-0.10.30.0-0.1-0.4-0.10.40.2-0.2-0.4-0.4
Tibia length2.26.118.61.11.2-1.1-4.33.00.6-3.0-2.7-0.71.7-3.63.3-3.43.5-1.62.51.6-3.23.2-1.6-2.81.61.61.0
Ambulatory time before self-admin0.90.92.91.61.7-1.4-1.61.1-0.9-1.2-1.7-1.40.6-0.70.8-0.50.60.50.2-0.5-0.30.50.4-0.5-0.4-0.4-0.6
Ambulatory time after self-admin2.42.68.1-0.4-0.20.5-2.31.81.4-2.0-1.40.4-0.1-2.32.2-0.62.8-2.01.41.7-0.02.0-1.6-1.91.81.51.6
Bone: tissue strength0.50.52.9-0.8-0.50.61.5-0.80.20.91.70.8-0.20.7-0.70.5-1.30.1-0.1-0.10.4-0.40.00.4-0.10.00.2
Total heroin consumption0.81.02.6-0.9-0.90.71.6-1.60.21.50.60.30.91.3-1.31.2-1.00.4-1.0-0.20.9-1.10.81.2-1.0-0.7-0.1
Bone: trabecular number0.81.25.1-2.3-2.02.01.2-1.61.31.71.31.50.30.4-0.70.5-0.2-0.8-0.00.60.1-0.1-0.50.50.40.40.6
Bone: trabecular spacing0.81.02.51.31.3-1.20.0-0.1-1.30.2-1.1-1.60.30.9-0.70.4-0.51.4-0.9-1.40.4-1.11.00.9-1.1-1.0-1.2
Bone: trabecular thickness1.41.75.9-2.4-2.32.10.1-1.62.01.7-1.00.82.4-0.0-0.50.81.6-0.9-0.40.80.3-0.0-0.50.80.50.50.7
Bone: trabecular tissue density0.20.21.60.70.2-0.6-0.50.4-0.3-0.4-1.2-0.7-0.10.10.10.50.70.3-0.30.10.6-0.40.30.2-0.1-0.3-0.2
Water consumed over 24 hours0.40.51.8-0.8-0.70.9-0.30.31.1-0.3-0.50.60.3-0.50.50.71.3-1.10.10.81.00.4-0.7-0.30.70.71.1
Number of responses in last shaping day0.30.31.2-0.1-0.10.1-0.50.30.1-0.40.50.3-0.6-0.70.6-1.10.3-0.60.70.6-1.10.7-0.4-0.70.40.40.3