Hub : Genes

Wsb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr12_44880363_44880470 0.1 0.06 9.2e-10 0.1 0.09 0.1 0.04 3.5e-11 7.7e-10 3.0e-11 9.1e-06
2 Adipose mRNA stability Wsb2 0.04 0.02 1.7e-03 0.01 0.02 0 0.01 1.5e-02 1.2e-03 2.4e-01 7.1e-03
3 Adipose gene expression Wsb2 0.02 0.01 5.1e-04 0.01 0.02 0.03 0.01 7.8e-03 1.5e-03 1.1e-04 1.2e-02
4 NAcc gene expression Wsb2 0.06 0.03 1.7e-11 0.07 0.07 0.07 0.07 1.8e-11 6.3e-11 1.1e-10 1.7e-11
5 PL gene expression Wsb2 0.1 0.05 5.3e-10 0.09 0.08 0.08 0.08 1.3e-09 1.1e-08 9.7e-09 3.0e-09
6 Brain gene expression Wsb2 0.05 0.03 4.1e-05 0.04 0.04 0.03 0.04 2.0e-04 2.5e-04 4.0e-04 3.1e-04
7 Adipose intron excision ratio chr12_44880580_44881070 0.13 0.07 6.0e-11 0.12 0.1 0.11 0.04 5.0e-13 1.0e-10 2.4e-12 1.6e-05
8 Brain mRNA stability Wsb2 0.15 0.09 4.4e-08 0.09 0.05 0.08 0.07 1.3e-08 2.1e-05 5.8e-08 2.5e-07
9 BLA gene expression Wsb2 0.07 0.04 2.9e-04 0.06 0.06 0.05 0.05 3.7e-04 4.4e-04 1.2e-03 1.6e-03
10 PL mRNA stability Wsb2 0.04 0.02 2.2e-05 0.01 0.04 0.03 0.04 1.6e-02 4.1e-05 1.2e-04 8.0e-05
11 OFC mRNA stability Wsb2 0.16 0.09 4.8e-03 0.09 0.07 0.09 0.09 4.1e-03 8.7e-03 3.7e-03 3.7e-03
12 Liver gene expression Wsb2 0.26 0.08 0.0e+00 0.25 0.23 0.24 0.25 1.5e-27 1.6e-25 1.4e-26 6.7e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.52.88.20.30.1-2.91.6-2.1-2.1-2.2-2.2-1.20.81.60.2
Area under the delay curve1.11.75.62.4-0.91.6-1.51.11.01.11.11.3-1.1-0.5-0.9
BMI with tail0.20.72.2-1.5-0.9-0.8-0.3-0.20.3-1.2-1.20.70.6-0.60.5
BMI without tail0.10.31.1-0.5-1.00.1-0.7-0.10.7-0.6-0.60.9-0.1-0.7-0.2
Body weight0.31.12.7-1.6-0.3-0.60.0-0.60.4-1.6-1.60.31.3-0.81.6
Weight adjusted by age0.61.84.80.82.2-0.71.6-1.2-1.4-0.9-0.9-1.41.81.01.4
Bone surface0.10.30.7-0.2-0.7-0.5-0.70.40.40.30.30.3-0.8-0.6-0.7
Bone volume0.20.41.90.5-0.7-1.4-0.0-0.4-0.5-0.4-0.4-0.2-0.60.3-0.7
Breakpoint value in progressive ratio session0.30.64.0-2.0-0.20.6-0.40.20.70.00.00.50.4-1.10.8
Number of licking bursts0.82.44.7-0.01.7-0.92.2-1.5-1.7-1.5-1.5-2.01.71.41.3
Context. condit. distance diff. score0.30.41.0-0.00.81.0-0.30.80.60.80.8-0.2-0.2-0.4-0.2
Locomotion velocity, session 10.60.62.3-1.11.50.20.00.50.10.90.90.20.7-0.51.1
Locomotion distance, session 10.20.21.8-1.30.1-0.7-0.10.1-0.10.20.20.5-0.3-0.2-0.1
Locomotion velocity, session 20.20.21.91.40.40.1-0.20.1-0.00.40.4-0.1-0.50.3-0.4
Locomotion distance, session 20.30.51.9-1.4-0.5-1.10.1-0.8-0.4-0.8-0.80.30.10.10.0
Locomotion velocity, session 30.50.62.6-0.81.60.60.20.2-0.00.10.1-0.61.0-0.41.2
Locomotion distance, session 30.50.51.6-1.11.10.9-0.00.20.10.10.1-0.21.0-0.61.3
Stereotopy head waving bouts, day 31.21.43.41.40.2-1.11.2-1.4-1.4-1.2-1.2-1.50.31.8-0.4
Stereotopy head waving duration, day 30.50.61.40.80.6-0.40.8-0.9-0.9-0.5-0.5-1.20.51.20.1
Locomotion velocity, session 73.94.38.4-2.3-0.22.7-2.32.62.71.91.91.9-0.2-2.90.8
Locomotion distance, session 72.43.16.1-1.6-1.41.6-2.21.82.31.41.42.4-0.9-2.5-0.2
Stereotopy head waving bouts, day 71.01.23.31.21.00.11.0-1.3-1.2-0.7-0.7-1.70.61.8-0.0
Stereotopy head waving duration, day 71.11.43.50.71.90.21.2-1.2-1.3-0.6-0.6-1.81.21.50.9
Locomotion velocity, session 80.30.31.9-1.40.3-0.70.5-0.4-0.4-0.6-0.6-0.40.30.10.1
Locomotion distance, session 80.10.10.8-0.9-0.2-0.2-0.30.20.30.10.10.2-0.5-0.2-0.6
Degree of sensitization distance1.11.23.20.0-1.60.1-1.40.81.30.70.71.8-1.2-1.1-0.9
Degree of sensitization stereotypy0.60.61.60.61.30.40.6-0.8-0.8-0.3-0.3-1.20.81.00.5
Conditioned locomotion0.40.41.30.91.20.10.5-0.2-0.3-0.2-0.2-1.10.80.50.6
Cocaine response after cond. corrected0.71.03.3-0.20.0-1.81.1-1.2-1.3-1.0-1.0-0.70.11.4-0.3
Cocaine response after cond. not corrected0.20.30.90.3-0.0-0.90.6-0.7-0.8-0.3-0.3-0.2-0.10.9-0.3
Cocaine response before conditioning1.51.86.91.1-0.32.6-1.41.21.51.61.61.0-0.3-1.2-0.0
Saline control response0.30.41.2-0.00.2-0.41.0-0.4-0.4-0.8-0.8-1.1-0.10.9-0.3
Bone: connectivity density0.91.44.00.40.5-2.01.1-1.4-1.3-1.5-1.5-0.90.90.90.5
Bone: cortical apparent density0.20.42.3-1.5-0.9-0.20.20.00.00.10.1-0.2-0.70.1-0.7
Bone: cortical area3.15.18.4-0.9-1.91.6-2.92.92.72.22.22.8-1.8-2.8-0.9
Bone: cortical porosity2.72.95.91.6-2.40.6-1.81.91.71.01.01.7-2.2-1.3-2.1
Bone: cortical porosity3.53.96.21.4-2.51.1-2.22.42.31.31.32.1-2.4-1.8-2.1
Bone: cortical thickness1.83.15.8-1.3-1.41.4-2.12.42.21.61.62.1-1.1-2.3-0.3
Bone: cortical thickness1.41.73.7-0.1-1.41.2-1.41.91.71.11.11.4-1.3-1.3-0.8
Bone: cortical tissue density0.20.42.3-1.5-0.9-0.20.20.0-0.00.10.1-0.2-0.80.1-0.8
Condit. Reinf. active minus inactive responses1.61.84.5-1.4-0.40.7-1.41.41.61.31.32.1-0.6-2.10.2
Condit. Reinf. active-inactive response ratio0.30.41.6-1.30.3-0.5-0.20.20.30.50.50.9-0.1-0.90.2
Condit. Reinf. active responses2.22.96.5-0.6-0.61.6-2.01.92.21.71.72.5-0.7-2.50.2
Condit. Reinf. inactive responses1.11.43.00.9-0.91.7-1.51.11.50.90.91.5-0.5-1.3-0.1
Incentive salience index mean1.01.33.4-0.1-0.60.8-1.41.11.41.11.11.8-0.8-1.6-0.1
Condit. Reinf. lever presses0.40.54.02.0-0.50.7-0.70.10.50.30.30.6-0.50.0-0.5
Condit. Reinf. active minus inactive responses0.91.52.50.5-1.31.5-1.41.41.61.21.20.8-1.2-1.0-1.0
Condit. Reinf. active-inactive response ratio0.81.21.7-0.5-0.91.2-1.31.31.31.21.21.1-1.0-1.0-0.7
Condit. Reinf. active responses0.60.92.51.4-1.61.0-1.00.71.10.50.50.5-1.0-0.3-1.0
Condit. Reinf. inactive responses0.40.63.92.0-0.9-0.20.2-0.6-0.2-0.7-0.7-0.4-0.20.8-0.4
Condit. Reinf. lever presses2.02.96.92.6-1.42.1-1.91.61.91.71.71.1-1.6-0.8-1.3
Condit. Reinf. lever reinforcers received0.81.22.81.5-1.71.2-1.20.81.30.70.70.7-1.1-0.4-1.0
Conditioned reinforcement - actives0.31.33.5-0.00.0-0.40.8-1.8-0.9-1.9-1.9-0.41.41.01.1
Conditioned reinforcement - inactives0.30.91.9-1.0-0.11.4-1.01.11.20.90.90.90.0-1.30.7
Conditioned locomotion1.52.24.90.70.6-1.31.4-2.2-1.7-1.8-1.8-1.21.61.61.0
Patch foraging indifference point 0 sec0.20.42.81.7-0.61.3-0.20.00.30.00.0-0.0-0.30.2-0.4
Patch foraging indifference point AUC0.10.20.50.7-0.70.4-0.40.10.50.30.30.4-0.70.2-0.7
Delay disc. indifference point, 0s delay0.10.21.0-0.30.41.0-0.20.30.20.40.4-0.20.2-0.40.4
Delay disc. indifference point, 16s delay0.71.09.83.10.10.6-0.30.50.10.40.4-0.0-0.50.4-0.7
Delay disc. indifference point, 2s delay1.41.63.2-0.7-0.41.5-1.51.61.21.81.81.3-0.4-1.30.1
Delay disc. indifference point, 24s delay0.40.63.21.8-0.8-0.10.2-0.8-0.2-0.5-0.5-0.3-0.70.8-1.1
Delay disc. indifference point, 4s delay1.11.13.00.5-1.40.7-1.50.80.90.80.81.7-1.1-0.8-0.8
Delay disc. indifference point, 8s delay1.72.88.42.9-1.32.5-2.01.31.61.21.21.7-1.5-0.7-1.1
Indifference point function ln k0.00.10.60.20.80.20.20.20.00.30.3-0.50.10.00.0
Indifference point function log k0.00.10.60.20.80.20.20.20.00.30.3-0.50.10.00.0
Patch foraging total patch changes 0 sec0.20.62.81.7-0.81.5-0.40.20.50.20.20.2-0.50.1-0.6
Patch foraging total patch changes 12 sec0.50.62.20.7-1.51.5-0.80.40.80.30.30.8-0.4-0.4-0.3
Patch foraging total patch changes 18 sec0.61.52.71.4-0.3-0.51.1-1.6-1.4-1.6-1.6-0.91.01.50.6
Patch foraging total patch changes 24 sec0.10.21.11.00.10.50.0-0.2-0.0-0.1-0.1-0.10.80.10.7
Patch foraging total patch changes 6 sec0.10.21.01.0-0.70.9-0.30.00.60.00.00.3-0.2-0.1-0.1
Patch foraging time to switch 0 sec1.04.06.5-0.92.2-1.62.3-2.0-2.3-1.9-1.9-2.02.61.32.2
Patch foraging water rate 0 sec0.62.23.81.3-1.81.1-1.81.71.61.31.31.0-2.0-0.9-1.8
Patch foraging water rate 12 sec0.52.14.32.1-0.1-1.41.6-1.5-1.5-1.6-1.6-1.60.12.0-0.7
Patch foraging water rate 18 sec0.20.52.61.6-0.4-0.50.5-0.4-0.4-0.5-0.5-0.6-0.40.8-0.8
Patch foraging water rate 24 sec0.20.31.31.1-1.1-0.4-0.1-0.20.0-0.6-0.6-0.3-0.50.4-0.6
Patch foraging water rate 6 sec0.60.83.11.1-1.8-0.5-0.90.40.30.10.10.4-1.4-0.0-1.5
Seeking ratio, delayed vs. immediate footshock0.20.30.8-0.4-0.8-0.90.4-0.5-0.3-0.9-0.9-0.50.10.2-0.2
Distance traveled before self-admin1.02.26.3-0.80.4-2.51.9-1.1-1.9-1.4-1.4-2.10.31.4-0.4
Distance traveled after self-admin0.61.11.7-1.0-0.7-0.91.2-1.1-1.3-0.9-0.9-1.1-0.51.3-1.2
Extensor digitorum longus weight0.41.63.01.01.0-0.91.5-1.3-1.2-1.4-1.4-1.71.41.10.9
Bone: elastic displacement0.50.71.70.2-0.71.3-0.71.00.71.01.00.6-0.8-0.6-0.8
Bone: elastic work1.62.03.70.1-1.21.5-1.51.91.61.51.51.3-1.6-1.5-1.1
Bone: endosteal estimation0.20.51.81.3-1.0-0.2-0.30.00.20.30.30.1-1.20.1-1.4
Bone: endosteal perimeter0.61.63.20.7-1.40.7-1.41.31.11.41.41.1-1.8-0.9-1.5
Epididymis fat weight0.73.77.10.22.7-1.42.2-1.9-2.1-2.0-2.0-1.82.31.32.0
Delta time in closed arm before/after self-admin0.10.10.30.30.20.5-0.20.10.4-0.2-0.20.1-0.1-0.3-0.3
Delta time in open arm before/after self-admin0.40.41.4-0.2-0.5-1.20.10.3-0.50.70.7-0.2-0.90.3-1.0
Diff in mean of infusions in LGA sessions0.40.71.4-1.20.9-0.91.0-0.6-0.6-0.8-0.8-0.51.00.21.1
Delay discount exponential model param1.11.65.0-2.20.9-1.61.5-1.0-1.0-1.1-1.1-1.31.10.50.9
Extinction: sum of active levers before priming0.20.30.8-0.3-0.9-0.50.0-0.5-0.10.10.10.2-0.70.5-0.9
Active lever presses in extinction session 61.41.56.7-2.61.50.20.40.10.00.70.7-0.31.6-0.72.0
Bone: final force2.13.46.4-0.0-2.50.8-2.42.22.21.41.42.2-2.0-2.0-1.3
Bone: final moment2.33.86.9-0.0-2.61.1-2.52.42.41.51.52.3-2.0-2.1-1.3
Food consumed during 24 hour testing period0.61.13.0-1.3-0.31.2-1.11.71.30.80.80.4-0.0-1.60.4
Glucose1.52.46.4-0.5-2.50.6-1.91.51.51.01.02.0-1.9-1.3-1.4
Heart weight0.81.22.80.50.7-1.71.3-1.1-1.2-1.3-1.3-1.20.41.3-0.0
Delay discount hyperbolic model param1.31.63.3-1.80.9-1.71.7-1.1-1.1-1.3-1.3-1.51.10.70.8
Intermittent access intake day 1-15 change0.00.20.4-0.50.6-0.10.5-0.50.2-0.5-0.5-0.40.40.40.3
Intermittent access intake escalation0.00.30.9-0.90.60.10.4-0.50.4-0.6-0.6-0.30.50.30.5
Intermittent access intake escalation 20.10.21.0-1.00.8-0.20.2-0.20.5-0.2-0.2-0.20.4-0.00.5
Intermitt. access day 1 inactive lever presses0.00.51.71.1-0.2-0.20.4-0.2-0.50.00.0-0.9-0.91.1-1.3
Intermitt. access day 15 inactive lever presses0.10.81.5-0.3-0.31.2-1.01.11.01.01.00.8-0.8-0.9-0.5
Intermitt. access escalation Index0.20.72.41.50.4-0.80.8-0.5-1.0-0.2-0.2-0.9-0.31.1-0.7
Intermittent access day 1 total infusions0.10.42.2-1.1-1.50.3-0.60.00.0-0.1-0.10.8-0.2-0.5-0.1
Intermittent access day 15 total infusions0.20.53.4-1.8-0.80.3-0.5-0.00.5-0.4-0.40.80.1-0.50.3
Intermittent access terminal intake (last 3 days)0.20.42.2-1.5-0.90.2-0.60.20.5-0.1-0.10.8-0.3-0.6-0.1
Intermittent access total infusions0.70.82.5-1.4-1.60.5-1.00.40.6-0.0-0.01.4-0.4-1.0-0.1
Intermittent access day 1 locomotion0.20.31.8-1.2-1.30.2-0.2-0.20.10.10.10.3-0.4-0.0-0.4
Intermittent access day 15 total locomotion0.00.20.7-0.4-0.5-0.10.4-0.9-0.3-0.3-0.3-0.40.00.6-0.4
Intermittent access total locomotion0.40.52.5-1.1-1.60.1-0.4-0.10.3-0.0-0.00.6-0.8-0.2-0.9
Intermittent access standard deviation0.21.06.4-2.5-0.70.6-0.90.20.80.60.61.20.0-1.00.6
Left kidney weight0.76.011.12.50.3-3.32.3-2.9-2.7-3.3-3.3-2.11.12.40.4
Right kidney weight0.75.28.42.60.5-2.92.2-2.8-2.5-2.9-2.9-2.01.02.40.4
Cocaine induced anxiety0.51.33.61.90.91.3-0.61.50.31.61.60.1-0.9-0.7-0.4
Post-drug Anxiety1.31.53.70.90.61.5-1.01.80.81.91.90.5-0.8-1.1-0.4
Baseline Anxiety0.20.41.3-1.1-0.70.5-0.70.30.90.40.40.7-0.1-0.6-0.3
Tail length0.00.10.40.10.20.6-0.40.30.60.30.3-0.0-0.3-0.50.0
Length with tail0.10.41.5-1.00.60.10.0-0.10.5-0.4-0.4-0.10.7-0.71.2
Length without tail0.20.82.5-1.00.6-1.00.7-0.5-0.5-1.0-1.0-0.41.3-0.01.6
Times rat made contact with spout0.60.72.10.10.41.5-0.51.21.00.90.9-0.30.3-0.90.6
Lifetime Intake0.30.31.3-0.8-1.10.0-0.3-0.3-0.0-0.8-0.80.70.2-0.30.4
Liver weight, left0.40.72.0-1.4-1.3-0.7-0.90.70.80.10.11.0-0.8-1.0-0.3
Liver weight, right0.61.13.8-1.00.1-1.90.5-0.6-0.6-1.6-1.60.20.8-0.21.0
Locomotor activity0.20.31.20.71.10.70.30.2-0.20.20.2-0.40.7-0.00.9
Locomotor testing distance0.20.42.4-0.50.51.5-0.20.60.40.70.70.20.4-0.50.6
Locomotor testing rearing0.41.53.6-0.41.40.51.4-1.1-1.1-1.0-1.0-1.41.90.71.7
Locomotion in novel chamber0.81.13.1-0.4-1.81.2-1.30.81.20.40.41.4-0.8-0.9-0.5
Locomotion in novel chamber post-restriction0.72.18.4-1.3-2.9-0.0-1.20.91.10.90.91.2-2.1-0.7-1.8
Fecal boli incidents, locomotor time 10.82.24.8-0.30.72.2-1.41.51.41.91.91.50.2-2.10.9
Change in fecal boli incidents, locomotor task1.11.24.6-1.1-1.4-2.20.7-1.0-0.5-1.5-1.5-0.1-0.30.6-0.6
Time >=10cm from walls, locomotor time 10.30.41.30.2-0.2-0.80.4-0.5-0.4-1.1-1.1-0.60.00.4-0.2
Bouts of movement, locomotor time 11.82.34.21.2-1.41.9-2.01.41.91.51.51.9-1.1-1.2-0.7
Total resting periods, locomotor time 11.11.32.90.8-1.11.3-1.60.91.41.01.01.7-0.6-1.0-0.2
Rest time, locomotor task time 11.82.95.9-0.81.0-1.91.6-2.3-1.6-1.9-1.9-0.72.40.92.3
Distance moved, locomotor task time 10.51.44.2-0.3-0.90.8-0.81.51.11.41.40.2-1.9-0.3-2.0
Vertical activity count, locomotor time 10.31.83.60.0-1.11.0-1.21.91.71.41.40.4-1.9-0.5-1.9
Time >=10cm from walls, locomotor time 20.10.20.7-0.6-0.8-0.2-0.1-0.10.4-0.4-0.40.1-0.40.1-0.6
Bouts of movement, locomotor time 20.30.94.92.2-1.11.0-0.80.20.50.40.40.3-1.00.3-1.2
Total resting periods, locomotor time 20.20.74.02.0-0.90.8-0.50.00.30.30.30.0-0.90.6-1.1
Rest time, locomotor task time 20.61.02.50.1-0.6-1.60.9-1.5-1.2-1.3-1.3-0.50.50.90.0
Distance moved, locomotor task time 21.31.73.3-0.9-1.11.2-1.21.51.51.41.40.7-1.8-0.6-1.7
Vertical activity count, locomotor time 20.20.40.9-0.70.00.7-0.51.00.90.60.60.2-0.6-0.4-0.4
Light reinforcement 10.10.50.90.1-0.90.9-0.70.80.60.80.80.6-0.9-0.3-0.7
Light reinforcement 20.10.31.1-0.5-1.0-0.4-0.50.40.10.10.11.0-0.8-0.4-0.6
Bone: marrow area0.20.51.81.2-1.0-0.1-0.40.10.30.40.40.1-1.20.0-1.3
Bone: maximum diameter2.75.38.70.2-2.11.7-2.92.92.82.42.42.5-2.2-2.7-1.3
Bone: maximum force0.91.83.8-0.4-1.90.5-1.71.51.70.80.81.5-1.4-1.6-0.9
Bone: maximum moment1.12.14.1-0.4-2.00.8-1.91.71.90.90.91.6-1.5-1.7-1.0
Mean time between licks in bursts0.10.92.00.40.2-1.40.9-1.2-1.1-1.0-1.0-0.60.11.4-0.2
Mean num. licks in bursts1.43.66.4-0.1-1.41.6-2.52.42.42.12.12.1-1.5-2.2-0.8
Cd content in liver0.20.30.70.20.70.8-0.20.60.40.80.8-0.3-0.1-0.0-0.1
Co content in liver0.40.53.71.9-0.50.7-0.40.40.40.30.30.3-0.5-0.0-0.7
Cu content in liver0.20.20.60.50.80.30.4-0.3-0.3-0.3-0.3-0.40.80.10.6
Fe content in liver1.92.45.2-0.42.3-0.71.7-1.4-1.5-1.1-1.1-2.31.91.51.6
K content in liver0.30.32.81.70.10.50.1-0.00.0-0.0-0.0-0.4-0.30.2-0.3
Mg content in liver0.50.61.11.01.00.00.8-0.5-0.5-0.7-0.7-0.71.00.50.9
Mn content in liver1.31.47.92.80.4-0.60.9-1.1-1.2-0.9-0.9-1.10.41.4-0.0
Na content in liver0.40.40.9-0.70.31.0-0.51.00.70.70.7-0.10.2-0.60.6
Rb content in liver0.60.82.0-1.30.80.8-0.40.60.70.20.20.80.9-1.21.4
Se content in liver0.10.10.60.20.40.20.2-0.3-0.2-0.2-0.2-0.80.60.40.4
Sr content in liver0.90.84.02.0-0.4-0.90.4-0.6-0.7-0.5-0.5-0.6-0.61.1-1.1
Zn content in liver1.01.22.51.60.9-0.41.1-1.1-0.9-1.2-1.2-1.11.31.10.8
Bone: minimum diameter1.02.04.4-0.5-1.70.5-1.51.31.31.21.21.4-2.1-1.1-1.9
Time in familiar zone, hab. session 10.70.84.10.0-2.0-0.6-0.7-0.50.3-0.2-0.20.6-1.2-0.0-1.4
Time in novel zone, hab. session 10.40.41.6-0.41.00.60.30.1-0.0-0.3-0.3-0.21.2-0.61.3
Total zone transitions, hab. session 10.71.02.6-1.6-1.6-1.30.3-1.0-0.3-1.2-1.20.5-0.50.1-0.8
Total locomotion distance, hab. session 10.70.93.7-0.9-1.9-0.5-0.60.20.50.00.01.0-1.6-0.4-1.5
Locomotion velocity, hab. session 10.50.72.8-0.9-1.7-0.7-0.4-0.10.3-0.1-0.10.8-1.4-0.2-1.3
Time in familiar zone, hab. session 20.30.31.11.00.1-0.60.4-0.7-0.6-0.6-0.6-0.50.20.6-0.1
Time in novel zone, hab. session 20.20.22.1-1.4-0.30.2-0.1-0.10.10.00.00.20.2-0.40.2
Total zone transitions, hab. session 20.70.93.9-2.0-1.4-0.9-0.0-0.5-0.1-1.2-1.20.9-0.2-0.4-0.3
Total locomotion distance, hab. session 20.91.24.8-1.7-2.2-0.3-0.90.50.6-0.2-0.21.1-1.2-0.7-1.2
Locomotion velocity, hab. session 20.60.83.9-1.4-2.0-0.5-0.70.20.3-0.4-0.40.8-1.0-0.4-1.1
Novel to familiar place preference ratio0.10.20.60.6-0.60.8-0.20.70.5-0.0-0.0-0.2-0.2-0.2-0.3
Novelty place preference0.10.20.60.7-0.50.8-0.20.60.50.00.0-0.2-0.1-0.3-0.2
Time in novel zone, NPP test0.20.20.70.4-0.70.8-0.40.70.60.00.00.1-0.2-0.5-0.3
Total zone transitions, NPP test0.40.52.6-1.6-0.9-0.80.1-0.4-0.1-0.9-0.90.60.1-0.30.1
Total locomotion distance, NPP test0.20.31.4-1.2-0.9-0.2-0.30.00.2-0.3-0.30.6-0.0-0.60.1
Locomotion velocity, NPP test0.10.10.6-0.8-0.6-0.2-0.30.20.1-0.3-0.30.40.0-0.40.2
Intraocular pressure0.50.82.10.4-0.2-1.40.6-1.0-1.0-1.4-1.4-0.30.30.7-0.1
Delta distance traveled before/after self-admin0.30.31.10.7-0.80.7-0.1-0.4-0.00.10.10.3-0.70.7-1.1
Delta ambulatory time before/after self-admin0.61.02.40.6-1.61.1-0.90.30.70.80.80.9-1.40.1-1.5
Parametrial fat weight0.30.61.4-0.3-0.70.3-0.91.01.20.50.51.0-0.8-0.9-0.5
Pavlov. Cond. lever latency1.62.03.8-1.31.5-0.71.5-1.6-1.3-1.4-1.4-1.52.00.51.8
Pavlov. Cond. magazine entry latency1.82.47.81.0-2.10.0-1.31.00.91.21.21.5-2.5-0.1-2.8
Pavlov. Cond. change in total contacts2.73.07.71.1-2.80.7-1.71.11.31.01.01.9-2.6-0.5-2.7
Pavlov. Cond. index score1.72.25.20.7-1.80.3-1.51.31.21.41.41.7-2.2-0.5-2.3
Pavlov. Cond. latency score2.12.65.00.8-1.70.8-1.81.71.51.71.71.8-2.2-0.7-2.1
Pavlov. Cond. lever contacts1.62.04.11.3-1.70.5-1.51.31.31.21.21.5-2.0-0.5-2.0
Pavlov. Cond. magazine entry number2.22.89.3-0.42.50.11.5-1.2-1.0-1.2-1.2-1.72.80.33.0
Pavlov. Cond. intertrial magazine entries1.92.28.3-2.91.9-0.30.5-0.3-0.4-0.3-0.3-0.02.2-1.02.9
Pavlov. Cond. lever-magazine prob. diff.1.62.05.90.8-2.00.0-1.31.00.91.11.11.5-2.3-0.2-2.4
Pavlov. Cond. response bias2.43.010.00.9-2.8-0.2-1.51.11.01.01.01.7-2.9-0.2-3.2
Pavlov. Cond. lever latency1.72.310.1-3.21.7-1.11.3-0.8-0.9-1.0-1.0-0.52.0-0.22.1
Pavlov. Cond. magazine entry latency0.60.91.51.0-0.71.1-1.00.60.91.21.20.2-1.1-0.3-1.0
Pavlov. Cond. change in total contacts0.92.13.51.7-1.61.4-1.51.21.31.51.50.9-1.9-0.5-1.8
Pavlov. Cond. index score1.21.95.82.4-1.61.1-1.30.81.01.21.20.6-1.8-0.1-1.7
Pavlov. Cond. latency score1.11.85.32.3-1.61.2-1.30.81.11.11.10.6-1.7-0.2-1.7
Pavlov. Cond. lever contacts1.82.611.03.3-1.91.0-1.30.80.91.11.10.5-2.20.3-2.4
Pavlov. Cond. magazine entry number0.81.01.6-0.71.0-0.91.3-0.7-1.2-1.1-1.1-0.81.10.80.9
Pavlov. Cond. intertrial magazine entries0.20.40.9-0.50.00.4-0.70.50.90.60.60.80.2-0.90.6
Pavlov. Cond. lever-magazine prob. diff.1.21.84.62.2-1.61.0-1.30.81.01.21.20.7-1.8-0.2-1.7
Pavlov. Cond. response bias1.72.46.52.5-1.90.9-1.41.01.11.31.30.7-2.2-0.0-2.2
Time in closed arm before self-admin0.10.21.40.31.2-0.20.4-0.0-0.40.20.2-0.10.7-0.10.8
Time in closed arm after self-admin0.10.10.60.40.8-0.30.5-0.4-0.3-0.3-0.3-0.30.20.30.0
Time in open arm before self-admin0.60.83.6-1.9-1.80.3-0.60.20.8-0.3-0.30.6-0.5-0.3-0.5
Time in open arm after self-admin0.30.31.5-0.3-1.2-0.6-0.20.2-0.20.30.3-0.2-0.70.4-0.9
Bone: periosteal estimation1.33.04.60.2-2.00.9-2.11.91.91.71.71.9-2.1-1.8-1.6
Bone: periosteal perimeter1.22.33.80.3-1.41.0-1.91.91.61.61.61.8-1.5-1.7-0.9
Bone: post-yield work0.20.41.9-0.5-1.4-0.7-0.4-0.30.4-0.2-0.20.3-0.9-0.1-1.0
Progressive ratio test 1 active lever presses0.20.41.10.1-1.1-0.50.3-0.6-0.8-0.8-0.8-0.2-0.10.5-0.5
Progressive ratio test 1 breakpoint0.20.31.10.1-1.1-0.50.2-0.6-0.7-0.7-0.7-0.2-0.20.5-0.5
Progressive ratio test 1 inactive lever presses0.61.54.0-2.0-1.31.3-1.21.11.01.41.41.2-0.6-1.3-0.2
Progressive ratio test 2 active lever presses0.20.30.8-0.4-0.60.1-0.1-0.70.0-0.9-0.90.40.40.00.5
Progressive ratio test 2 breakpoint0.20.20.5-0.6-0.60.2-0.2-0.50.2-0.7-0.70.60.3-0.10.5
Progressive ratio test 2 inactive lever presses0.61.95.4-2.3-0.81.6-1.51.21.61.01.01.7-0.1-1.70.6
Incentive Sensitization - Responses0.30.71.8-1.20.11.4-0.70.41.10.10.11.10.4-1.01.0
Incentive Sensitization - Breakpoint0.30.71.7-1.10.21.3-0.70.41.10.20.21.10.4-1.01.0
Sum of active levers in priming session hrs 5-61.41.34.6-2.1-0.30.6-0.91.31.21.41.40.7-0.4-1.50.1
Progressive ratio0.20.52.71.7-0.1-0.60.2-0.6-0.4-1.0-1.00.10.30.30.1
Food seeking constrained by brief footshock0.30.41.7-0.70.5-0.40.2-0.5-0.5-0.5-0.50.31.1-0.21.3
Seeking ratio, punishment vs. effort0.20.32.4-1.60.7-0.00.4-0.2-0.30.10.1-0.40.50.10.6
Retroperitoneal fat weight0.83.66.10.22.3-2.52.3-1.6-1.9-2.0-2.0-2.01.91.51.5
Reaction time number correct0.62.26.6-1.2-0.32.6-1.51.71.71.71.71.0-0.4-1.70.1
Reaction time mean minus median0.10.53.0-0.7-0.1-1.70.7-0.3-0.7-0.7-0.7-0.6-0.10.4-0.2
Reaction time mean minus median AUC0.00.31.0-0.3-0.2-1.00.6-0.1-0.5-0.3-0.3-0.8-0.60.6-0.9
Reaction time num false alarms0.71.24.52.1-1.61.1-1.10.60.80.40.40.4-1.40.1-1.2
Reaction time num false alarms AUC0.61.34.92.2-1.61.3-1.10.60.90.30.30.4-1.30.1-1.2
Reaction time trials correct on left0.62.26.6-1.2-0.32.6-1.51.71.71.71.71.0-0.4-1.70.1
Reaction time trials on left0.62.06.1-1.3-0.32.5-1.41.61.61.61.61.0-0.3-1.60.2
Reaction time mean0.51.05.40.10.6-2.30.9-1.1-1.4-0.8-0.8-0.60.40.90.2
Reaction time mean AUC0.41.04.8-0.10.6-2.21.0-1.1-1.4-0.8-0.8-0.70.31.00.0
Median of all reaction times0.71.15.30.40.7-2.30.9-1.2-1.5-0.8-0.8-0.50.41.00.3
Reaction time omissions0.30.51.8-0.90.2-1.40.8-0.5-0.8-0.9-0.9-0.40.30.50.2
Reaction time false alarm rate0.81.16.92.6-1.4-0.1-0.3-0.20.0-0.4-0.4-0.1-1.20.9-1.3
Reaction time premature initiation rate1.11.73.50.70.61.6-1.11.91.51.91.90.5-0.3-1.40.3
Reaction time premature initiations1.13.57.9-0.10.32.8-1.82.52.22.62.61.0-0.5-2.20.4
Std. dev. reaction times0.20.52.8-0.2-0.2-1.70.6-0.6-0.9-0.6-0.6-0.6-0.20.7-0.4
Reaction time trials completed0.62.06.1-1.3-0.32.5-1.41.61.61.61.61.0-0.3-1.60.2
Reaction time trials AUC0.51.95.6-1.2-0.32.4-1.41.61.51.61.60.9-0.3-1.60.2
Run reversals in cocaine runway, females0.60.71.90.80.2-1.40.8-1.0-1.1-0.8-0.8-0.60.21.1-0.3
Run reversals in cocaine runway, males0.70.82.2-0.11.2-0.00.9-0.8-0.9-0.7-0.7-1.51.10.90.8
Latency to leave start box in cocaine runway1.01.32.7-0.3-1.2-1.41.1-1.3-1.0-1.6-1.6-0.9-0.41.4-0.8
Latency to leave start box in cocaine runway, F0.91.13.5-0.1-0.2-1.91.2-0.9-1.0-1.4-1.4-1.0-0.01.1-0.3
Latency to leave start box in cocaine runway, M1.31.22.70.3-1.6-0.20.9-1.6-0.9-1.4-1.4-0.8-0.31.5-0.9
Std. dev. time between licks in bursts0.10.20.40.10.6-0.30.4-0.5-0.4-0.5-0.5-0.60.30.40.1
Total sessions with >9 infusions0.30.32.2-0.6-1.5-0.2-0.2-0.4-0.1-0.7-0.70.3-0.30.1-0.3
Short access day 1 total inactive lever presses0.10.20.9-1.0-0.30.5-0.40.40.40.40.40.50.1-0.70.5
Short access day 10 total inactive lever presses0.21.32.9-0.60.01.2-1.11.51.21.71.71.0-0.8-1.3-0.1
Short access day 1 total infusions0.20.30.8-0.6-0.9-0.0-0.1-0.6-0.0-0.8-0.80.30.5-0.10.7
Short access day 10 total infusions0.20.30.9-0.4-0.8-0.00.3-0.7-0.6-1.0-1.0-0.10.20.30.1
Short access total infusions0.30.42.0-0.4-1.4-0.2-0.0-0.7-0.3-1.1-1.10.30.10.20.1
Short access day 1 locomotion1.93.17.40.5-0.6-1.61.7-2.7-1.6-2.7-2.7-1.50.82.20.2
Short access day 10 total locomotion0.10.41.7-1.2-1.30.2-0.0-0.60.20.10.1-0.0-0.70.5-0.9
Short access total locomotion0.40.63.2-1.4-1.8-0.2-0.1-0.7-0.1-0.4-0.40.1-0.60.4-0.7
One hour access (0.3 mA shock)0.10.10.50.1-0.0-0.20.1-0.5-0.1-0.7-0.70.20.30.10.3
Compulsive drug intake0.20.21.3-0.11.1-0.10.50.1-0.00.40.4-0.70.30.30.4
One hour access (shock baseline)0.10.20.5-0.2-0.3-0.00.0-0.5-0.3-0.7-0.70.30.4-0.00.3
Social response proportion0.50.72.0-0.7-0.80.9-1.00.71.10.20.21.4-0.2-1.20.1
Social responses0.91.22.11.3-1.21.4-1.31.01.40.60.61.3-0.8-1.1-0.5
Social time0.30.42.31.51.20.20.40.1-0.10.10.10.10.60.00.7
Soleus weight0.30.93.71.40.7-0.41.1-0.8-0.8-0.6-0.6-1.90.61.10.3
Bone: stiffness0.10.30.8-0.3-0.9-0.6-0.70.30.5-0.2-0.20.6-0.1-0.70.3
Tibialis anterior weight5.117.627.52.43.4-4.05.0-5.0-4.8-4.4-4.4-5.23.44.91.7
Time to tail flick, vehicle, before self-admin4.25.17.32.12.4-2.12.4-2.3-2.5-2.7-2.7-2.12.21.71.6
Time to tail flick, vehicle, after self-admin1.12.26.81.92.6-0.91.5-1.3-1.3-0.9-0.9-1.31.71.31.3
Time to tail flick, test, before self-admin0.60.73.50.31.10.2-0.0-0.00.0-0.6-0.60.11.5-0.71.9
Time to tail flick, test, after self-admin0.40.41.00.70.50.6-0.60.40.90.30.30.50.5-0.71.0
Delta time to tail flick, vehicle, before/after SA1.31.43.80.10.42.0-1.11.21.21.81.80.9-0.2-0.90.2
Delta time to tail flick, test, before/after SA0.30.40.90.7-0.10.6-0.40.40.60.90.90.1-0.80.1-0.8
Tibia length1.54.38.1-1.4-1.01.9-2.62.62.62.32.32.2-1.1-2.8-0.1
Ambulatory time before self-admin0.72.25.1-0.80.3-2.32.0-1.5-1.9-1.4-1.4-2.00.31.7-0.4
Ambulatory time after self-admin0.61.02.7-0.4-0.9-1.00.9-0.9-1.1-0.5-0.5-0.9-1.01.4-1.7
Bone: tissue strength0.50.51.2-1.0-1.1-0.9-0.1-0.4-0.1-0.9-0.90.0-0.40.1-0.8
Total heroin consumption0.30.41.7-0.40.6-1.30.8-0.4-0.7-0.3-0.3-0.70.00.5-0.2
Bone: trabecular number1.32.46.80.6-0.0-2.61.5-2.1-1.8-2.0-2.0-0.90.61.6-0.0
Bone: trabecular spacing0.40.61.4-1.20.31.1-0.61.00.70.80.80.70.2-0.70.7
Bone: trabecular thickness1.41.95.42.1-1.1-2.30.7-1.2-1.4-1.3-1.3-0.8-0.61.5-1.1
Bone: trabecular tissue density0.00.00.1-0.20.1-0.10.00.0-0.4-0.1-0.1-0.30.00.30.0
Water consumed over 24 hours0.20.31.10.5-0.11.0-0.40.90.60.40.4-0.70.2-0.50.1
Number of responses in last shaping day0.20.31.40.20.6-0.60.0-0.5-0.5-0.2-0.20.20.8-0.21.2