Hub : Genes

Wnt7b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_118537241_118554792 0.01 0.01 9.7e-03 0.02 0.01 0.01 0.01 9.5e-04 2.3e-02 1.8e-02 6.6e-03
2 NAcc intron excision ratio chr7_118537241_118558876 0.01 0.01 7.8e-03 0.01 0.01 0.01 0.01 1.7e-03 1.9e-02 2.3e-02 4.9e-03
3 NAcc mRNA stability Wnt7b 0.02 0.01 5.6e-04 0.02 0.01 0.02 0.01 1.2e-03 4.1e-03 1.5e-03 4.2e-03
4 Brain mRNA stability Wnt7b 0.03 0.02 2.5e-03 0.03 0.03 0.02 0 1.4e-03 1.7e-03 6.6e-03 2.1e-01
5 Eye isoform ratio NM_001009695.2 0.43 0.21 3.5e-03 0.06 0.12 0.09 0.09 4.3e-02 7.5e-03 1.6e-02 1.7e-02
6 Brain isoform ratio NM_001009695.2 0.04 0.02 1.1e-03 0.01 0.02 0.02 0.02 6.4e-02 3.8e-03 4.8e-03 6.6e-03
7 Brain alternative TSS NM_001412610.1 0.03 0.02 1.8e-03 0 0.02 0.02 0.02 1.0e-01 2.8e-03 3.6e-03 1.2e-02
8 Brain alternative TSS NM_001009695.2 0.04 0.03 1.5e-03 0.01 0.02 0.02 0.01 6.8e-02 2.3e-03 7.6e-03 2.2e-02
9 Brain alternative TSS NM_001009695.2 0.03 0.02 1.8e-03 0.01 0.03 0.03 0.02 9.1e-02 2.1e-03 1.7e-03 8.8e-03
10 IL alternative TSS NM_001009695.2 0.17 0.11 9.2e-03 0.02 0.02 0 0.01 1.3e-01 9.2e-02 2.9e-01 2.1e-01
11 PL gene expression Wnt7b 0.06 0.04 6.5e-03 0.03 0.01 0.01 0.02 2.4e-04 8.2e-03 9.5e-03 1.2e-03
12 IL isoform ratio NM_001009695.2 0.16 0.1 8.2e-03 0.08 0.03 0.07 0.05 5.7e-03 6.2e-02 8.6e-03 2.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.50.91.7-1.21.2-1.1-1.31.00.9-0.90.90.80.50.70.4
Area under the delay curve1.11.23.4-1.31.3-1.8-1.61.61.0-0.90.80.60.6-0.3-0.0
BMI with tail2.910.211.83.3-3.33.23.3-3.3-3.43.3-3.4-3.4-3.0-2.6-2.7
BMI without tail0.31.01.70.8-0.81.31.2-1.2-1.11.0-1.0-1.3-0.8-0.7-0.5
Body weight1.56.710.53.0-3.03.23.2-2.8-2.52.5-2.5-2.7-1.6-1.8-1.1
Weight adjusted by age0.60.92.21.0-1.01.51.3-1.3-0.90.8-0.7-0.6-0.7-0.2-0.3
Bone surface0.20.30.8-0.70.7-0.6-0.90.60.5-0.50.50.30.30.20.4
Bone volume0.30.51.1-0.70.7-0.8-1.10.80.7-0.70.70.50.50.60.4
Breakpoint value in progressive ratio session0.60.71.70.6-0.60.50.1-0.8-0.90.9-0.9-0.6-1.3-0.6-1.2
Number of licking bursts0.81.31.9-1.21.2-0.5-0.81.01.1-1.11.11.01.31.41.3
Context. condit. distance diff. score1.51.83.71.9-1.91.21.4-1.4-1.31.3-1.3-1.1-0.9-1.3-0.3
Locomotion velocity, session 10.30.31.20.7-0.70.91.1-0.5-0.20.2-0.1-0.10.5-0.20.7
Locomotion distance, session 10.60.71.3-0.30.3-0.6-0.30.81.0-0.91.01.11.10.81.1
Locomotion velocity, session 21.61.94.11.9-1.92.01.8-1.4-1.21.2-1.2-1.3-0.2-0.4-0.1
Locomotion distance, session 20.10.10.50.4-0.4-0.3-0.20.0-0.20.2-0.3-0.2-0.4-0.4-0.7
Locomotion velocity, session 31.01.23.41.8-1.81.01.1-0.5-0.20.3-0.2-0.31.10.41.9
Locomotion distance, session 30.70.81.90.1-0.1-0.2-0.30.60.9-0.80.91.01.41.41.3
Stereotopy head waving bouts, day 31.51.72.91.3-1.31.31.3-1.2-1.41.4-1.4-1.7-0.8-1.6-0.1
Stereotopy head waving duration, day 33.03.55.51.9-1.92.32.2-2.0-2.02.0-1.9-2.2-1.4-1.4-0.5
Locomotion velocity, session 70.70.81.91.2-1.21.41.2-0.7-0.70.7-0.6-0.70.10.30.6
Locomotion distance, session 70.10.10.30.2-0.20.30.10.20.2-0.20.20.30.60.40.3
Stereotopy head waving bouts, day 71.01.12.61.6-1.61.21.2-1.1-1.01.0-0.9-1.0-0.3-0.10.5
Stereotopy head waving duration, day 70.40.51.00.9-0.90.81.0-0.8-0.70.7-0.7-0.7-0.20.10.4
Locomotion velocity, session 85.87.011.83.4-3.42.62.7-2.9-2.72.7-2.7-2.7-2.0-1.6-1.4
Locomotion distance, session 80.81.14.02.0-2.00.61.0-0.9-0.80.9-0.8-0.7-0.4-0.8-0.0
Degree of sensitization distance1.51.63.30.8-0.81.10.9-1.1-1.31.3-1.3-1.3-1.4-1.8-1.4
Degree of sensitization stereotypy0.60.61.51.2-1.20.80.8-0.9-0.70.7-0.6-0.7-0.30.20.4
Conditioned locomotion0.00.10.2-0.10.10.50.5-0.2-0.10.1-0.00.2-0.10.0-0.2
Cocaine response after cond. corrected0.50.62.2-0.80.80.20.20.30.7-0.80.80.70.91.50.6
Cocaine response after cond. not corrected1.11.34.5-1.01.00.10.10.71.1-1.21.31.21.42.11.0
Cocaine response before conditioning0.40.50.7-0.50.5-0.6-0.70.80.8-0.80.80.80.80.70.6
Saline control response0.50.72.0-0.80.8-0.5-0.10.30.8-0.91.01.40.41.20.7
Bone: connectivity density0.40.61.0-1.01.0-0.7-1.00.80.7-0.70.70.50.60.50.9
Bone: cortical apparent density0.71.02.0-1.31.3-1.4-1.31.20.9-0.80.80.90.5-0.00.3
Bone: cortical area0.91.42.81.0-1.01.61.6-1.7-1.21.1-1.0-1.0-1.2-0.0-1.1
Bone: cortical porosity0.30.30.8-0.00.00.40.7-0.9-0.60.5-0.5-0.4-0.80.0-0.9
Bone: cortical porosity0.50.61.10.3-0.30.60.8-1.1-0.80.8-0.7-0.7-1.0-0.3-1.0
Bone: cortical thickness0.10.20.9-0.50.50.10.1-0.4-0.30.2-0.2-0.1-0.7-0.1-0.9
Bone: cortical thickness1.72.13.90.4-0.41.41.5-1.7-1.51.5-1.4-1.4-1.8-1.2-2.0
Bone: cortical tissue density0.50.71.5-1.11.1-1.2-1.11.00.8-0.70.70.80.5-0.10.3
Condit. Reinf. active minus inactive responses0.50.61.3-1.21.2-1.1-0.90.80.7-0.70.70.60.50.00.2
Condit. Reinf. active-inactive response ratio0.90.92.0-1.21.2-1.3-1.41.10.9-0.90.80.80.5-0.10.1
Condit. Reinf. active responses1.31.62.3-1.31.3-1.5-1.21.41.3-1.31.21.11.30.41.2
Condit. Reinf. inactive responses0.70.92.7-0.40.4-0.8-0.61.01.0-1.00.90.91.30.51.6
Incentive salience index mean0.60.71.0-1.01.0-0.6-0.20.60.8-0.90.90.91.00.61.0
Condit. Reinf. lever presses0.50.72.7-0.20.20.41.00.00.6-0.60.80.81.21.01.6
Condit. Reinf. active minus inactive responses0.60.81.11.1-1.10.70.0-0.8-0.90.9-0.9-0.9-1.0-1.0-0.7
Condit. Reinf. active-inactive response ratio0.10.10.20.5-0.50.2-0.3-0.2-0.20.2-0.2-0.2-0.2-0.1-0.0
Condit. Reinf. active responses2.12.94.12.0-2.01.61.1-1.8-1.81.8-1.8-1.8-1.7-1.8-1.2
Condit. Reinf. inactive responses2.93.84.41.9-1.92.12.1-2.1-2.12.1-2.1-2.0-1.7-1.8-1.3
Condit. Reinf. lever presses1.31.72.71.7-1.71.41.1-1.3-1.41.4-1.4-1.4-1.1-1.0-0.9
Condit. Reinf. lever reinforcers received1.52.02.81.7-1.71.20.7-1.4-1.51.5-1.5-1.5-1.4-1.5-1.0
Conditioned reinforcement - actives0.10.10.2-0.20.2-0.2-0.20.30.3-0.30.30.40.3-0.30.4
Conditioned reinforcement - inactives0.10.10.30.5-0.50.20.1-0.3-0.20.2-0.2-0.0-0.2-0.60.1
Conditioned locomotion0.20.31.20.4-0.41.01.1-0.6-0.20.2-0.1-0.10.40.30.3
Patch foraging indifference point 0 sec0.20.41.2-1.11.1-0.2-0.30.30.5-0.50.50.40.30.9-0.2
Patch foraging indifference point AUC0.10.20.5-0.40.4-0.7-0.50.50.3-0.20.20.50.3-0.40.4
Delay disc. indifference point, 0s delay0.10.10.4-0.00.0-0.00.4-0.2-0.30.3-0.3-0.4-0.2-0.7-0.3
Delay disc. indifference point, 16s delay1.92.14.2-2.02.0-1.9-1.91.81.4-1.31.21.10.80.20.1
Delay disc. indifference point, 2s delay0.20.30.8-0.70.7-0.9-0.70.70.3-0.30.20.10.0-0.4-0.4
Delay disc. indifference point, 24s delay0.20.31.1-0.20.2-0.10.3-0.3-0.50.5-0.5-0.5-0.7-0.6-1.1
Delay disc. indifference point, 4s delay1.11.13.5-1.11.1-1.9-1.71.60.7-0.60.50.20.3-0.7-0.3
Delay disc. indifference point, 8s delay0.70.92.7-0.90.9-1.7-1.51.40.7-0.70.50.40.4-0.4-0.2
Indifference point function ln k0.61.03.11.2-1.21.81.8-1.3-0.60.5-0.4-0.5-0.20.60.0
Indifference point function log k0.61.03.11.2-1.21.81.8-1.3-0.60.5-0.4-0.5-0.20.60.0
Patch foraging total patch changes 0 sec0.30.61.6-1.31.3-0.4-0.50.60.7-0.80.70.70.51.2-0.1
Patch foraging total patch changes 12 sec0.10.10.20.1-0.1-0.00.1-0.1-0.40.4-0.4-0.4-0.3-0.5-0.1
Patch foraging total patch changes 18 sec0.81.22.3-1.51.5-0.9-1.11.11.1-1.11.11.01.00.90.9
Patch foraging total patch changes 24 sec0.10.21.0-0.40.4-0.10.00.30.4-0.40.40.50.51.00.4
Patch foraging total patch changes 6 sec0.30.51.5-1.21.2-0.8-0.60.70.6-0.60.50.50.30.4-0.2
Patch foraging time to switch 0 sec0.10.20.70.3-0.3-0.3-0.2-0.2-0.60.6-0.6-0.9-0.8-0.3-0.6
Patch foraging water rate 0 sec0.10.30.80.5-0.50.90.6-0.8-0.50.4-0.4-0.3-0.40.2-0.4
Patch foraging water rate 12 sec0.30.72.8-0.20.20.40.30.10.8-0.90.91.01.01.70.8
Patch foraging water rate 18 sec0.10.20.40.1-0.10.1-0.10.10.4-0.40.40.50.50.50.7
Patch foraging water rate 24 sec0.30.41.21.1-1.10.60.6-0.8-0.50.5-0.5-0.5-0.5-0.4-0.3
Patch foraging water rate 6 sec0.81.12.0-0.40.4-0.6-0.90.91.2-1.21.21.21.41.01.4
Seeking ratio, delayed vs. immediate footshock0.80.91.7-1.21.2-0.9-1.31.00.9-0.90.90.80.41.00.2
Distance traveled before self-admin0.60.71.8-0.90.9-0.4-0.20.60.9-0.90.90.71.20.71.3
Distance traveled after self-admin0.10.10.9-0.00.00.30.6-0.4-0.0-0.00.10.3-0.10.90.1
Extensor digitorum longus weight0.31.22.41.5-1.51.61.4-1.2-1.01.0-0.9-0.9-0.5-0.30.0
Bone: elastic displacement0.10.20.60.4-0.40.20.8-0.30.1-0.10.10.40.30.60.5
Bone: elastic work2.93.85.62.3-2.32.02.2-2.4-2.02.0-1.9-1.8-1.7-0.5-1.3
Bone: endosteal estimation1.94.27.62.8-2.82.52.3-2.3-2.02.0-1.9-1.9-1.3-0.7-0.9
Bone: endosteal perimeter1.63.57.22.3-2.32.72.5-2.4-1.71.6-1.5-1.4-1.00.6-0.7
Epididymis fat weight0.82.84.81.7-1.71.11.1-1.5-1.81.8-1.9-1.8-1.7-2.2-1.7
Delta time in closed arm before/after self-admin0.20.20.5-0.70.70.1-0.2-0.0-0.10.1-0.1-0.1-0.5-0.4-0.6
Delta time in open arm before/after self-admin0.90.93.30.7-0.7-0.1-0.00.40.8-0.80.90.81.51.21.8
Diff in mean of infusions in LGA sessions0.50.71.60.2-0.20.60.6-0.9-0.80.8-0.8-0.5-1.1-1.1-1.3
Delay discount exponential model param1.11.23.61.3-1.31.91.6-1.6-0.90.9-0.7-0.5-0.60.30.0
Extinction: sum of active levers before priming0.91.02.31.0-1.00.2-0.0-0.6-1.01.0-1.1-0.9-1.2-1.5-1.1
Active lever presses in extinction session 61.71.72.41.1-1.11.51.1-1.3-1.31.3-1.4-1.4-1.2-1.3-1.5
Bone: final force1.62.53.91.1-1.11.31.3-1.7-1.71.7-1.6-1.6-1.9-1.8-2.0
Bone: final moment2.13.45.21.2-1.21.51.6-1.9-2.01.9-1.9-1.9-2.3-2.1-2.3
Food consumed during 24 hour testing period2.23.05.41.4-1.42.32.2-2.3-1.91.8-1.7-1.7-1.4-1.2-0.8
Glucose0.30.61.7-1.31.3-0.7-0.50.50.6-0.70.80.70.40.30.3
Heart weight3.35.16.22.2-2.22.32.1-2.3-2.42.5-2.5-2.5-2.2-2.2-1.6
Delay discount hyperbolic model param1.21.33.71.2-1.21.91.7-1.7-1.00.9-0.8-0.5-0.60.4-0.0
Intermittent access intake day 1-15 change0.10.10.7-0.30.30.20.4-0.40.2-0.30.40.50.00.80.2
Intermittent access intake escalation0.10.30.8-0.40.4-0.2-0.00.00.5-0.60.70.80.40.90.6
Intermittent access intake escalation 20.40.40.9-1.01.0-0.7-0.50.20.5-0.60.70.70.00.90.1
Intermitt. access day 1 inactive lever presses0.20.81.50.5-0.50.40.3-0.7-1.01.0-1.0-1.0-1.2-1.2-1.1
Intermitt. access day 15 inactive lever presses0.40.71.20.2-0.21.01.1-1.1-0.90.8-0.8-0.6-1.0-1.1-0.9
Intermitt. access escalation Index0.40.60.9-0.90.9-0.6-0.60.70.8-0.90.91.00.50.50.2
Intermittent access day 1 total infusions0.30.51.71.0-1.01.31.0-0.6-0.20.2-0.2-0.10.7-0.40.9
Intermittent access day 15 total infusions0.40.62.20.1-0.10.50.4-0.10.7-0.70.91.01.20.81.5
Intermittent access terminal intake (last 3 days)0.20.31.10.4-0.41.00.7-0.60.1-0.10.30.30.60.30.9
Intermittent access total infusions0.30.30.80.7-0.70.90.8-0.6-0.00.00.10.20.60.10.9
Intermittent access day 1 locomotion0.40.51.9-0.10.10.40.00.40.7-0.60.70.71.40.31.2
Intermittent access day 15 total locomotion0.30.61.71.1-1.11.31.2-0.8-0.30.3-0.2-0.10.60.10.7
Intermittent access total locomotion0.50.61.61.3-1.31.20.9-0.8-0.50.5-0.4-0.30.3-0.30.6
Intermittent access standard deviation0.40.81.30.7-0.71.01.0-1.1-1.00.9-0.8-0.8-0.8-0.8-0.6
Left kidney weight11.452.976.98.8-8.88.38.3-8.0-7.47.4-7.2-7.2-5.3-5.2-3.3
Right kidney weight13.059.381.99.0-9.08.18.1-8.3-8.08.0-7.9-7.9-6.1-6.2-4.2
Cocaine induced anxiety1.62.34.01.3-1.30.80.8-1.3-1.61.7-1.7-1.7-1.8-2.0-1.6
Post-drug Anxiety0.70.72.0-0.00.0-0.4-0.3-0.3-0.70.8-0.9-0.8-1.3-1.3-1.4
Baseline Anxiety2.02.33.4-1.91.9-1.1-1.01.41.6-1.61.71.51.51.61.1
Tail length1.14.27.3-1.61.6-1.3-1.31.82.3-2.32.42.12.62.02.7
Length with tail0.10.52.20.7-0.70.80.9-0.30.1-0.10.2-0.00.90.21.5
Length without tail1.65.06.32.3-2.32.32.5-2.3-2.32.3-2.4-2.3-1.9-2.2-1.6
Times rat made contact with spout0.30.41.30.5-0.50.90.5-0.3-0.40.5-0.5-0.80.3-1.10.7
Lifetime Intake0.40.41.00.9-0.91.00.9-0.7-0.20.2-0.1-0.00.5-0.01.0
Liver weight, left0.71.13.11.5-1.51.61.8-1.0-0.60.6-0.6-0.60.1-0.80.5
Liver weight, right0.50.83.11.2-1.20.91.0-0.10.2-0.10.20.21.2-0.51.8
Locomotor activity1.11.75.01.3-1.32.22.2-1.6-1.11.1-1.0-1.4-0.1-0.30.0
Locomotor testing distance0.10.20.5-0.70.70.70.7-0.10.2-0.20.3-0.10.50.70.2
Locomotor testing rearing0.20.31.60.2-0.21.31.2-0.6-0.30.2-0.1-0.30.30.30.6
Locomotion in novel chamber1.82.35.2-0.90.9-0.1-0.31.11.7-1.71.81.62.32.11.9
Locomotion in novel chamber post-restriction0.00.00.1-0.20.2-0.30.10.20.1-0.10.10.2-0.00.00.1
Fecal boli incidents, locomotor time 10.30.51.41.2-1.20.50.6-0.5-0.70.7-0.8-0.7-0.3-0.50.0
Change in fecal boli incidents, locomotor task0.30.30.8-0.40.4-0.3-0.10.20.6-0.70.70.80.60.90.5
Time >=10cm from walls, locomotor time 10.80.91.20.7-0.71.00.8-0.9-1.11.1-1.1-1.0-1.0-0.9-0.8
Bouts of movement, locomotor time 10.50.61.30.6-0.60.50.5-0.7-0.80.9-0.9-0.9-0.7-1.1-0.4
Total resting periods, locomotor time 10.70.82.00.3-0.30.60.5-0.7-1.01.0-1.0-1.0-1.1-1.4-0.9
Rest time, locomotor task time 11.01.22.01.0-1.01.31.0-1.0-1.21.2-1.3-1.4-0.7-1.3-0.4
Distance moved, locomotor task time 10.00.00.1-0.20.2-0.00.3-0.1-0.00.00.00.1-0.10.3-0.2
Vertical activity count, locomotor time 10.10.20.4-0.60.6-0.3-0.10.10.2-0.30.30.4-0.20.6-0.5
Time >=10cm from walls, locomotor time 20.20.31.1-0.60.60.40.6-0.6-0.30.2-0.20.0-0.80.7-1.1
Bouts of movement, locomotor time 20.30.62.1-0.00.0-1.0-0.40.2-0.50.6-0.7-0.7-0.9-1.5-1.0
Total resting periods, locomotor time 20.40.62.9-0.00.0-1.1-0.60.3-0.50.6-0.7-0.8-0.9-1.7-0.9
Rest time, locomotor task time 21.51.94.1-0.70.7-1.5-1.61.91.5-1.41.20.92.0-0.11.9
Distance moved, locomotor task time 21.31.63.21.0-1.01.71.8-1.8-1.31.2-1.1-0.8-1.30.6-1.0
Vertical activity count, locomotor time 21.31.83.81.0-1.01.61.9-1.9-1.31.2-1.1-0.7-1.60.8-1.4
Light reinforcement 10.30.72.90.7-0.71.71.6-0.8-0.30.2-0.10.10.31.00.6
Light reinforcement 21.42.15.91.2-1.22.42.4-1.9-1.41.3-1.2-1.1-0.90.0-0.7
Bone: marrow area2.04.37.82.8-2.82.52.3-2.4-2.02.0-2.0-2.0-1.4-0.8-1.0
Bone: maximum diameter4.07.411.83.1-3.13.43.3-3.4-2.82.7-2.6-2.5-2.1-0.8-1.5
Bone: maximum force2.34.06.21.6-1.61.61.7-2.1-2.22.1-2.1-2.1-2.5-1.8-2.5
Bone: maximum moment2.95.27.61.7-1.71.81.9-2.4-2.42.4-2.4-2.4-2.8-2.1-2.8
Mean time between licks in bursts1.02.43.7-1.91.9-0.9-0.61.41.6-1.61.71.71.41.91.3
Mean num. licks in bursts1.52.45.81.6-1.61.11.3-1.4-1.51.6-1.6-1.5-1.3-2.4-1.1
Cd content in liver0.10.10.30.3-0.30.50.3-0.5-0.40.3-0.3-0.3-0.40.0-0.2
Co content in liver0.10.10.3-0.30.30.2-0.10.20.3-0.30.40.30.50.50.6
Cu content in liver3.64.26.9-2.62.6-2.6-2.42.32.0-2.01.82.00.92.0-0.1
Fe content in liver0.50.61.70.2-0.20.50.7-0.9-0.80.8-0.8-0.9-1.2-0.3-1.3
K content in liver0.10.10.30.6-0.6-0.30.2-0.1-0.10.1-0.10.1-0.2-0.2-0.3
Mg content in liver0.10.10.50.0-0.0-0.3-0.00.0-0.10.1-0.2-0.1-0.4-0.2-0.7
Mn content in liver0.30.30.91.0-1.00.50.9-0.30.0-0.00.10.20.6-0.00.8
Na content in liver0.70.71.8-0.80.8-1.3-1.21.00.8-0.80.70.90.20.8-0.1
Rb content in liver0.50.52.1-0.50.5-0.20.1-0.4-0.60.5-0.6-0.6-1.4-0.6-1.5
Se content in liver0.40.40.8-0.60.6-0.2-0.20.50.7-0.70.80.90.80.60.8
Sr content in liver0.90.71.9-0.60.6-0.6-0.91.00.9-0.80.80.81.20.21.4
Zn content in liver0.10.20.70.7-0.70.20.10.10.1-0.10.10.10.4-0.00.9
Bone: minimum diameter0.51.02.41.3-1.31.51.5-1.2-0.60.5-0.4-0.4-0.11.20.1
Time in familiar zone, hab. session 10.80.82.20.9-0.91.51.4-1.0-0.80.8-0.7-0.5-0.60.1-0.1
Time in novel zone, hab. session 10.20.20.5-0.70.7-0.7-0.40.20.3-0.30.40.20.00.3-0.3
Total zone transitions, hab. session 11.11.52.7-1.21.2-1.7-1.41.51.3-1.31.31.40.80.60.4
Total locomotion distance, hab. session 10.10.20.40.4-0.4-0.20.10.30.4-0.40.40.60.60.40.5
Locomotion velocity, hab. session 10.10.20.40.6-0.6-0.20.10.30.4-0.30.30.40.70.30.6
Time in familiar zone, hab. session 20.60.61.5-0.80.80.20.20.40.8-0.80.81.01.00.91.2
Time in novel zone, hab. session 20.20.20.7-0.10.1-0.8-0.80.1-0.00.0-0.1-0.2-0.4-0.3-0.8
Total zone transitions, hab. session 20.60.81.51.2-1.20.50.8-0.8-0.80.8-0.8-0.6-1.1-0.6-1.2
Total locomotion distance, hab. session 20.30.31.21.1-1.10.40.5-0.5-0.40.4-0.4-0.3-0.40.0-0.5
Locomotion velocity, hab. session 20.20.31.01.0-1.00.30.5-0.4-0.40.4-0.4-0.3-0.3-0.1-0.4
Novel to familiar place preference ratio0.10.10.50.4-0.4-0.5-0.40.20.2-0.20.20.20.2-0.00.7
Novelty place preference0.10.20.80.6-0.6-0.2-0.10.10.2-0.20.20.20.30.20.9
Time in novel zone, NPP test0.20.21.00.6-0.6-0.2-0.10.10.2-0.20.30.20.30.21.0
Total zone transitions, NPP test0.30.51.40.1-0.1-1.2-1.00.90.7-0.70.60.90.30.1-0.0
Total locomotion distance, NPP test0.10.20.70.9-0.9-0.4-0.40.30.2-0.20.10.20.10.50.1
Locomotion velocity, NPP test0.10.20.30.6-0.6-0.5-0.40.50.4-0.40.30.40.40.50.2
Intraocular pressure0.20.31.20.5-0.50.40.40.20.4-0.40.40.51.00.41.1
Delta distance traveled before/after self-admin0.50.61.11.0-1.01.01.0-0.9-0.60.6-0.5-0.3-0.60.4-0.6
Delta ambulatory time before/after self-admin0.40.50.90.9-0.91.00.9-0.8-0.60.5-0.5-0.2-0.60.4-0.5
Parametrial fat weight0.71.62.9-1.11.1-0.8-0.91.61.4-1.41.41.21.71.11.1
Pavlov. Cond. lever latency0.60.72.00.4-0.4-0.3-0.5-0.2-0.80.8-1.0-1.1-1.1-1.4-1.2
Pavlov. Cond. magazine entry latency0.70.91.9-1.41.4-0.7-0.70.70.9-1.01.01.10.50.9-0.1
Pavlov. Cond. change in total contacts0.40.41.6-1.31.3-0.1-0.20.20.5-0.50.60.40.10.8-0.3
Pavlov. Cond. index score0.50.61.2-1.11.1-0.3-0.20.40.8-0.80.91.00.61.00.2
Pavlov. Cond. latency score0.40.51.4-0.80.8-0.10.10.20.7-0.80.80.90.61.20.3
Pavlov. Cond. lever contacts0.81.02.7-0.80.80.10.40.41.0-1.01.21.21.21.61.2
Pavlov. Cond. magazine entry number0.81.02.31.5-1.50.80.8-0.8-1.01.1-1.1-1.1-0.7-0.80.1
Pavlov. Cond. intertrial magazine entries0.80.92.0-1.11.1-1.4-1.21.11.0-0.90.90.80.70.20.5
Pavlov. Cond. lever-magazine prob. diff.0.70.91.6-1.31.3-0.5-0.40.60.9-1.01.11.20.81.20.3
Pavlov. Cond. response bias0.81.01.9-1.41.4-0.2-0.20.61.0-1.11.21.21.01.20.5
Pavlov. Cond. lever latency0.81.11.8-1.31.3-0.9-0.51.01.1-1.11.11.21.10.70.8
Pavlov. Cond. magazine entry latency0.60.83.6-0.20.2-0.8-1.0-0.1-0.60.6-0.7-0.7-1.4-0.6-1.9
Pavlov. Cond. change in total contacts1.21.93.61.1-1.10.5-0.1-1.2-1.51.5-1.6-1.8-1.9-1.3-1.8
Pavlov. Cond. index score0.50.71.70.7-0.70.1-0.3-0.6-0.90.9-1.0-1.0-1.2-0.8-1.3
Pavlov. Cond. latency score0.70.92.40.7-0.70.2-0.1-0.7-1.01.0-1.1-1.1-1.4-0.7-1.5
Pavlov. Cond. lever contacts0.70.91.31.1-1.10.60.3-0.9-1.01.0-1.1-1.1-1.1-0.8-0.9
Pavlov. Cond. magazine entry number0.50.61.8-0.50.50.20.70.40.7-0.70.80.91.20.61.3
Pavlov. Cond. intertrial magazine entries0.91.32.40.9-0.90.80.9-1.1-1.31.3-1.3-1.2-1.3-1.5-1.1
Pavlov. Cond. lever-magazine prob. diff.0.50.61.30.7-0.70.0-0.4-0.5-0.80.8-0.9-0.9-1.1-0.7-1.2
Pavlov. Cond. response bias0.40.61.00.6-0.60.1-0.3-0.5-0.80.8-0.9-1.0-1.0-0.8-0.9
Time in closed arm before self-admin2.32.94.7-2.22.2-2.1-1.51.61.7-1.81.81.61.21.61.0
Time in closed arm after self-admin1.92.04.3-2.12.1-1.0-0.91.11.4-1.41.51.31.11.51.1
Time in open arm before self-admin0.20.20.60.8-0.80.60.4-0.2-0.40.4-0.5-0.5-0.1-0.2-0.3
Time in open arm after self-admin0.80.94.02.0-2.00.50.4-0.5-0.60.6-0.7-0.6-0.2-0.3-0.3
Bone: periosteal estimation2.04.16.82.4-2.42.62.4-2.5-2.02.0-1.9-1.8-1.5-0.5-1.3
Bone: periosteal perimeter1.72.87.41.9-1.92.72.5-2.3-1.51.4-1.2-1.1-0.70.6-0.3
Bone: post-yield work0.50.73.1-0.10.1-0.1-0.5-0.1-0.60.7-0.8-0.8-1.0-1.8-1.3
Progressive ratio test 1 active lever presses0.30.41.50.0-0.00.50.10.40.6-0.50.50.51.2-0.31.1
Progressive ratio test 1 breakpoint0.40.41.8-0.20.20.40.00.50.7-0.70.70.71.3-0.21.1
Progressive ratio test 1 inactive lever presses0.20.21.00.5-0.51.00.6-0.3-0.20.2-0.2-0.10.3-0.60.4
Progressive ratio test 2 active lever presses0.70.82.31.2-1.20.50.3-0.6-0.80.9-0.9-0.8-0.7-1.5-0.8
Progressive ratio test 2 breakpoint0.60.61.81.1-1.10.50.2-0.5-0.70.7-0.8-0.6-0.5-1.3-0.7
Progressive ratio test 2 inactive lever presses0.10.20.60.8-0.80.30.2-0.3-0.30.3-0.3-0.1-0.2-0.6-0.2
Incentive Sensitization - Responses1.01.43.21.3-1.30.30.2-0.9-1.21.2-1.3-1.1-1.4-1.8-1.5
Incentive Sensitization - Breakpoint1.41.83.61.4-1.40.50.4-1.1-1.31.4-1.5-1.3-1.5-1.9-1.6
Sum of active levers in priming session hrs 5-60.40.30.60.7-0.70.2-0.4-0.4-0.60.6-0.7-0.5-0.8-0.5-0.6
Progressive ratio0.10.20.9-0.60.6-0.6-0.90.60.3-0.20.2-0.10.3-0.20.1
Food seeking constrained by brief footshock0.50.61.00.7-0.70.90.9-1.0-0.90.9-0.8-0.8-0.9-0.2-0.6
Seeking ratio, punishment vs. effort1.11.73.21.0-1.01.21.6-1.5-1.41.3-1.3-1.0-1.8-0.5-1.5
Retroperitoneal fat weight2.510.512.63.5-3.53.43.2-3.3-3.43.4-3.4-3.4-2.6-2.9-2.3
Reaction time number correct0.20.30.6-0.60.6-0.4-0.60.60.6-0.60.60.60.70.80.3
Reaction time mean minus median0.20.41.2-0.10.1-1.1-0.70.70.6-0.60.50.30.70.60.8
Reaction time mean minus median AUC0.10.21.01.0-1.0-0.3-0.10.2-0.10.1-0.2-0.40.4-0.00.6
Reaction time num false alarms0.71.02.8-0.40.4-0.2-0.30.71.0-1.11.21.21.51.11.7
Reaction time num false alarms AUC0.71.13.9-0.10.1-0.2-0.30.71.1-1.11.21.21.61.02.0
Reaction time trials correct on left0.20.30.6-0.60.6-0.4-0.60.60.6-0.60.60.60.70.80.3
Reaction time trials on left0.20.40.6-0.60.6-0.5-0.60.60.7-0.70.60.60.70.80.3
Reaction time mean0.50.83.7-0.70.7-1.9-1.61.00.6-0.50.40.4-0.2-0.1-0.6
Reaction time mean AUC0.50.83.8-0.50.5-1.9-1.71.10.6-0.50.40.5-0.1-0.2-0.4
Median of all reaction times0.60.93.6-0.90.9-1.9-1.71.00.4-0.40.30.4-0.5-0.4-1.0
Reaction time omissions0.30.51.2-0.90.9-1.1-0.90.90.7-0.70.60.50.40.10.0
Reaction time false alarm rate0.30.42.20.0-0.00.00.00.30.6-0.60.70.71.10.51.5
Reaction time premature initiation rate2.33.26.21.0-1.00.50.5-1.6-2.02.0-2.1-2.1-2.5-2.2-2.2
Reaction time premature initiations0.91.73.50.6-0.60.10.0-1.1-1.41.5-1.5-1.6-1.9-1.6-1.8
Std. dev. reaction times0.30.62.6-0.30.3-1.6-1.21.00.7-0.70.60.60.50.20.5
Reaction time trials completed0.20.40.6-0.60.6-0.5-0.60.60.7-0.70.60.60.70.80.3
Reaction time trials AUC0.10.10.4-0.30.3-0.2-0.40.40.4-0.40.40.30.50.60.1
Run reversals in cocaine runway, females2.12.13.3-1.81.8-0.4-0.41.11.6-1.61.71.61.51.71.2
Run reversals in cocaine runway, males0.40.41.51.0-1.00.70.7-0.3-0.00.00.0-0.20.80.31.2
Latency to leave start box in cocaine runway0.91.02.20.8-0.81.51.5-1.3-1.01.0-0.9-0.8-0.7-0.1-0.7
Latency to leave start box in cocaine runway, F0.80.92.70.6-0.61.51.6-1.2-0.90.9-0.8-0.9-0.7-0.3-0.6
Latency to leave start box in cocaine runway, M0.20.20.30.5-0.50.40.2-0.5-0.40.4-0.3-0.2-0.30.3-0.4
Std. dev. time between licks in bursts0.20.21.5-0.40.4-0.20.0-0.3-0.30.3-0.3-0.2-0.8-0.1-1.2
Total sessions with >9 infusions1.61.93.81.9-1.91.91.7-1.4-1.21.2-1.1-1.1-0.4-0.90.3
Short access day 1 total inactive lever presses2.02.64.02.0-2.01.82.0-1.9-1.61.5-1.5-1.3-1.2-1.3-0.9
Short access day 10 total inactive lever presses0.41.01.51.2-1.20.60.8-1.1-1.11.1-1.1-1.2-1.0-0.7-0.8
Short access day 1 total infusions0.30.51.10.9-0.91.10.9-0.7-0.40.4-0.3-0.30.2-0.30.8
Short access day 10 total infusions0.30.41.60.6-0.61.31.1-0.7-0.30.3-0.3-0.20.3-0.40.4
Short access total infusions0.91.22.51.4-1.41.61.4-1.3-1.01.0-0.9-0.8-0.3-0.80.2
Short access day 1 locomotion0.00.00.10.2-0.20.30.3-0.2-0.20.2-0.1-0.1-0.0-0.30.2
Short access day 10 total locomotion0.51.03.5-0.70.70.20.10.81.0-1.01.10.91.90.61.5
Short access total locomotion0.10.20.5-0.20.20.60.6-0.10.2-0.20.30.30.70.30.7
One hour access (0.3 mA shock)0.30.41.00.8-0.80.91.0-0.8-0.40.4-0.3-0.3-0.10.00.0
Compulsive drug intake0.60.81.30.9-0.90.10.3-0.7-1.01.0-1.0-1.0-1.2-1.0-0.9
One hour access (shock baseline)0.20.30.70.1-0.10.70.7-0.20.4-0.40.50.60.80.80.8
Social response proportion0.60.72.30.5-0.51.51.1-1.2-0.90.8-0.7-0.7-0.7-0.1-0.5
Social responses0.40.62.70.4-0.41.61.5-0.9-0.40.4-0.3-0.20.20.30.4
Social time1.62.24.6-2.22.2-0.7-0.41.31.5-1.51.61.41.70.61.4
Soleus weight0.72.04.21.5-1.50.91.0-1.2-1.41.4-1.5-1.5-1.3-2.1-1.4
Bone: stiffness1.11.76.2-0.10.10.30.1-1.1-1.31.3-1.3-1.4-2.3-0.9-2.5
Tibialis anterior weight0.00.00.10.1-0.1-0.1-0.10.1-0.10.1-0.2-0.2-0.3-0.2-0.4
Time to tail flick, vehicle, before self-admin0.10.11.10.2-0.20.1-0.20.20.00.0-0.1-0.00.3-1.10.2
Time to tail flick, vehicle, after self-admin0.10.10.40.3-0.3-0.2-0.10.10.3-0.30.20.10.4-0.20.6
Time to tail flick, test, before self-admin0.20.20.80.2-0.20.90.9-0.5-0.20.2-0.0-0.10.30.10.6
Time to tail flick, test, after self-admin0.10.10.3-0.50.5-0.3-0.2-0.10.2-0.20.30.2-0.40.6-0.6
Delta time to tail flick, vehicle, before/after SA1.61.62.21.4-1.40.91.1-1.2-1.31.3-1.3-1.5-1.3-1.0-1.0
Delta time to tail flick, test, before/after SA0.70.72.4-0.80.8-1.5-1.30.70.6-0.70.60.7-0.20.5-0.7
Tibia length0.10.20.50.7-0.70.10.5-0.4-0.20.2-0.3-0.2-0.2-0.2-0.2
Ambulatory time before self-admin0.71.02.7-0.70.7-0.6-0.40.81.1-1.01.11.01.50.71.6
Ambulatory time after self-admin0.60.72.0-0.80.8-0.4-0.20.40.9-0.91.01.10.71.40.6
Bone: tissue strength0.40.41.5-0.00.0-0.4-0.0-0.2-0.50.5-0.6-0.5-0.9-0.9-1.2
Total heroin consumption2.83.35.71.9-1.91.31.1-1.6-1.91.9-2.0-1.7-2.2-1.7-2.4
Bone: trabecular number1.42.43.1-1.81.8-1.3-1.41.51.6-1.61.61.51.41.41.5
Bone: trabecular spacing4.15.57.62.6-2.62.72.3-2.5-2.52.5-2.5-2.6-1.9-1.3-1.8
Bone: trabecular thickness0.50.61.0-0.80.8-1.0-0.70.70.8-0.80.80.80.60.60.7
Bone: trabecular tissue density0.30.42.0-0.30.3-1.3-1.40.80.3-0.20.10.1-0.1-0.4-0.1
Water consumed over 24 hours0.70.91.70.7-0.71.21.1-1.3-1.11.1-1.0-1.1-0.7-0.8-0.1
Number of responses in last shaping day0.20.21.1-1.01.0-0.1-0.10.30.2-0.20.20.20.1-0.1-0.0