Hub : Genes

Wdr75

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Wdr75 0.05 0.04 7.3e-03 0.03 0.02 0.02 0.02 1.3e-02 3.1e-02 2.5e-02 3.6e-02
2 BLA gene expression Wdr75 0.34 0.16 0.0e+00 0.27 0.23 0.24 0.26 1.9e-14 2.3e-12 4.7e-13 5.4e-14
3 pVTA mRNA stability Wdr75 0.07 0.06 2.7e-05 0.05 0.06 0.04 0.05 6.9e-05 2.8e-05 2.6e-04 3.9e-05
4 IC gene expression Wdr75 0.41 0.14 0.0e+00 0.29 0.32 0.32 0.31 7.9e-13 2.9e-14 3.1e-14 1.1e-13
5 Adipose mRNA stability Wdr75 0.28 0.13 0.0e+00 0.12 0.12 0.12 0.13 1.4e-13 1.4e-13 5.6e-13 5.2e-14
6 NAcc gene expression Wdr75 0.15 0.08 0.0e+00 0.14 0.15 0.15 0.15 8.0e-21 2.0e-22 1.5e-21 1.9e-21
7 Adipose gene expression Wdr75 0.19 0.1 0.0e+00 0.11 0.12 0.11 0.11 3.8e-12 1.1e-12 2.5e-12 3.3e-12
8 PL mRNA stability Wdr75 0.07 0.04 4.3e-09 0.05 0.07 0.06 0.06 1.7e-06 1.9e-08 2.7e-07 3.0e-07
9 NAcc mRNA stability Wdr75 0.07 0.04 1.2e-11 0.07 0.06 0.07 0.07 1.9e-10 4.2e-10 1.9e-10 1.7e-10
10 OFC gene expression Wdr75 0.57 0.16 4.3e-10 0.26 0.27 0.28 0.27 5.8e-07 5.0e-07 2.7e-07 3.3e-07
11 RMTg mRNA stability Wdr75 0.2 0.12 1.3e-04 0.13 0.13 0.07 0.11 3.1e-04 2.2e-04 6.3e-03 7.8e-04
12 PL gene expression Wdr75 0.63 0.12 0.0e+00 0.29 0.31 0.29 0.3 4.7e-32 3.0e-34 1.9e-31 3.7e-33
13 Brain gene expression Wdr75 0.22 0.11 0.0e+00 0.25 0.27 0.27 0.27 3.0e-23 2.0e-25 6.8e-25 4.3e-25
14 Brain mRNA stability Wdr75 0.19 0.1 0.0e+00 0.21 0.23 0.26 0.23 4.1e-19 2.3e-21 2.6e-24 4.4e-21
15 Liver mRNA stability Wdr75 0.06 0.04 3.5e-06 0.02 0.03 0.01 0.02 1.2e-03 2.4e-04 6.9e-03 1.2e-03
16 IL gene expression Wdr75 0.46 0.19 2.8e-06 0.14 0.13 0.1 0.13 2.7e-04 4.7e-04 1.7e-03 4.3e-04
17 Liver gene expression Wdr75 0.06 0.04 1.4e-06 0.01 0.02 0.01 0.01 9.7e-03 3.9e-03 1.3e-02 5.9e-02
18 RMTg gene expression Wdr75 0.19 0.12 5.9e-04 0.04 0.1 0.1 0.09 2.5e-02 1.4e-03 1.4e-03 2.4e-03
19 pVTA gene expression Wdr75 0.14 0.08 9.3e-07 0.05 0.05 0.06 0.06 4.9e-05 8.1e-05 1.4e-05 1.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density2.44.15.0-2.21.9-2.12.1-2.12.12.1-2.0-2.22.2-2.02.12.0-2.2-1.92.11.81.81.1
Area under the delay curve0.00.00.2-0.1-0.0-0.10.1-0.10.10.1-0.10.1-0.4-0.10.00.1-0.0-0.1-0.20.10.1-0.1
BMI with tail1.34.57.12.4-2.62.7-2.62.5-2.3-2.22.22.1-2.42.0-2.0-1.92.01.7-2.0-1.5-1.50.5
BMI without tail0.20.53.4-0.10.1-0.10.2-0.20.40.4-0.5-0.90.4-0.50.60.6-0.4-0.70.70.90.91.9
Body weight0.00.10.4-0.50.1-0.20.3-0.40.30.2-0.3-0.70.5-0.20.60.2-0.6-0.20.50.20.2-0.1
Weight adjusted by age1.01.54.41.1-0.70.7-0.90.9-1.0-1.11.11.3-0.91.1-1.6-1.21.31.3-1.1-1.4-1.5-2.1
Bone surface0.00.10.7-0.20.0-0.10.0-0.0-0.0-0.10.1-0.20.10.2-0.0-0.2-0.10.20.0-0.3-0.3-0.8
Bone volume0.61.11.9-1.41.2-1.21.2-1.21.11.1-1.0-1.11.2-1.01.00.9-1.2-0.81.10.70.7-0.1
Breakpoint value in progressive ratio session1.41.72.4-1.31.5-1.41.4-1.31.31.4-1.4-1.21.3-1.41.01.3-1.4-1.31.41.31.30.9
Number of licking bursts1.22.03.4-1.41.0-1.11.2-1.31.31.4-1.4-1.31.3-1.41.71.5-1.3-1.51.41.61.71.8
Context. condit. distance diff. score0.80.95.1-0.40.7-0.60.6-0.50.70.8-0.9-0.80.4-1.00.41.0-0.7-1.10.61.31.32.3
Locomotion velocity, session 10.10.10.2-0.30.3-0.20.2-0.30.30.3-0.3-0.30.2-0.30.40.3-0.3-0.30.10.40.30.4
Locomotion distance, session 10.50.60.90.7-0.90.8-0.90.8-0.8-0.80.80.9-0.70.8-0.9-0.80.70.8-0.6-0.8-0.8-0.5
Locomotion velocity, session 21.61.92.71.4-1.61.6-1.61.4-1.4-1.51.51.5-1.01.5-1.1-1.41.21.4-1.0-1.4-1.4-1.0
Locomotion distance, session 21.52.13.01.3-1.71.5-1.51.4-1.5-1.51.51.2-1.31.5-1.4-1.51.41.5-1.3-1.5-1.5-1.2
Locomotion velocity, session 30.10.10.20.2-0.40.3-0.30.3-0.3-0.20.20.0-0.30.2-0.4-0.20.20.2-0.2-0.1-0.20.2
Locomotion distance, session 30.10.10.8-0.20.0-0.10.1-0.10.20.2-0.2-0.60.1-0.3-0.00.3-0.2-0.30.30.40.40.9
Stereotopy head waving bouts, day 30.50.50.90.8-0.70.8-0.80.8-0.7-0.70.70.8-0.90.7-0.6-0.70.70.7-0.9-0.6-0.6-0.3
Stereotopy head waving duration, day 30.00.00.10.00.10.0-0.0-0.00.00.1-0.00.0-0.1-0.00.20.0-0.1-0.1-0.10.10.10.1
Locomotion velocity, session 72.12.33.41.5-1.51.4-1.41.4-1.4-1.51.51.8-1.41.5-1.4-1.61.51.6-1.5-1.6-1.6-1.8
Locomotion distance, session 71.21.52.11.3-1.31.1-1.21.1-1.2-1.21.21.2-1.01.3-1.1-1.31.31.3-1.1-1.3-1.3-1.4
Stereotopy head waving bouts, day 70.40.40.7-0.80.6-0.70.7-0.60.60.7-0.7-0.50.6-0.70.40.7-0.6-0.60.60.60.60.6
Stereotopy head waving duration, day 70.50.51.0-1.00.7-0.80.8-0.80.80.8-0.8-0.70.8-0.80.60.7-0.8-0.70.70.70.70.3
Locomotion velocity, session 80.00.00.40.1-0.10.0-0.00.10.00.1-0.10.10.0-0.1-0.10.10.0-0.20.00.30.20.6
Locomotion distance, session 80.20.30.70.7-0.70.7-0.70.6-0.6-0.50.50.3-0.70.4-0.7-0.30.50.3-0.5-0.1-0.10.8
Degree of sensitization distance1.11.13.41.0-0.80.8-0.80.7-0.9-0.91.01.3-0.81.1-0.6-1.11.01.1-1.0-1.2-1.2-1.8
Degree of sensitization stereotypy0.50.50.8-0.90.6-0.80.7-0.70.70.7-0.7-0.70.7-0.80.40.8-0.7-0.70.70.70.70.7
Conditioned locomotion0.00.00.3-0.20.1-0.10.1-0.10.10.1-0.1-0.6-0.1-0.00.10.1-0.0-0.0-0.10.00.00.0
Cocaine response after cond. corrected1.21.42.31.0-1.41.1-1.11.0-1.2-1.21.21.0-0.81.3-1.0-1.31.11.3-0.9-1.4-1.4-1.5
Cocaine response after cond. not corrected1.31.54.81.0-1.20.9-1.00.9-1.1-1.21.20.9-0.81.3-1.0-1.31.11.4-1.0-1.6-1.6-2.2
Cocaine response before conditioning0.10.21.20.30.2-0.0-0.10.1-0.2-0.20.30.2-0.30.3-0.5-0.30.30.4-0.4-0.5-0.5-1.1
Saline control response0.20.20.6-0.50.7-0.40.4-0.50.40.4-0.5-0.30.4-0.50.10.5-0.4-0.50.50.60.50.8
Bone: connectivity density0.20.30.7-0.50.4-0.50.5-0.50.50.5-0.5-0.80.7-0.50.40.5-0.7-0.40.70.40.40.3
Bone: cortical apparent density4.35.98.02.6-2.82.8-2.72.7-2.6-2.62.52.3-2.52.4-2.3-2.42.42.3-2.3-2.1-2.1-0.9
Bone: cortical area0.81.21.60.9-1.01.1-1.11.1-1.1-1.11.21.0-1.01.2-1.1-1.20.91.2-0.9-1.3-1.3-1.3
Bone: cortical porosity1.11.22.0-1.31.4-1.31.2-1.11.11.2-1.2-0.80.9-1.20.71.1-1.0-1.10.71.11.00.8
Bone: cortical porosity0.90.91.9-1.21.4-1.21.2-1.11.01.1-1.0-0.80.7-1.00.61.0-0.9-0.90.50.80.80.3
Bone: cortical thickness0.91.62.21.3-1.41.5-1.51.5-1.3-1.31.31.0-1.41.3-1.3-1.21.11.2-1.1-1.1-1.1-0.3
Bone: cortical thickness0.30.40.60.4-0.60.6-0.60.6-0.6-0.70.70.5-0.60.7-0.7-0.70.60.7-0.6-0.7-0.8-0.8
Bone: cortical tissue density4.25.77.82.6-2.82.7-2.72.6-2.5-2.52.52.3-2.42.4-2.3-2.42.42.3-2.3-2.1-2.1-0.9
Condit. Reinf. active minus inactive responses3.53.95.6-2.42.3-2.22.2-2.22.12.0-2.0-2.12.1-1.91.91.9-2.0-1.81.91.71.60.6
Condit. Reinf. active-inactive response ratio2.42.53.6-1.91.8-1.81.7-1.71.61.6-1.6-1.91.8-1.51.51.5-1.6-1.41.61.31.30.6
Condit. Reinf. active responses1.62.03.2-1.81.6-1.71.6-1.71.51.5-1.4-1.41.5-1.31.51.3-1.4-1.21.21.01.0-0.1
Condit. Reinf. inactive responses0.20.20.70.3-0.40.3-0.30.2-0.3-0.40.40.8-0.40.4-0.1-0.40.40.4-0.6-0.5-0.5-0.8
Incentive salience index mean3.23.95.5-2.42.2-2.22.1-2.12.12.0-2.0-2.02.1-2.01.82.0-2.0-1.91.91.81.70.9
Condit. Reinf. lever presses1.52.22.8-1.71.5-1.61.5-1.41.51.5-1.5-1.41.3-1.61.21.5-1.4-1.51.21.51.51.3
Condit. Reinf. active minus inactive responses0.70.91.9-1.01.4-1.31.2-1.11.11.0-1.0-0.61.3-0.90.60.9-1.0-0.71.20.60.5-0.5
Condit. Reinf. active-inactive response ratio1.51.72.8-1.31.7-1.61.5-1.41.41.4-1.4-0.91.3-1.41.01.3-1.2-1.21.31.11.10.3
Condit. Reinf. active responses0.10.10.6-0.20.4-0.30.2-0.20.10.1-0.1-0.20.4-0.0-0.2-0.0-0.10.10.3-0.2-0.2-0.7
Condit. Reinf. inactive responses0.70.91.40.8-0.80.9-1.00.9-1.0-1.11.10.8-0.71.1-1.0-1.10.91.1-0.8-1.1-1.2-1.2
Condit. Reinf. lever presses0.00.00.2-0.20.2-0.10.1-0.20.10.1-0.1-0.20.4-0.10.10.1-0.2-0.00.4-0.0-0.0-0.1
Condit. Reinf. lever reinforcers received0.10.10.90.00.2-0.10.0-0.0-0.1-0.10.20.00.20.2-0.3-0.20.10.30.1-0.4-0.5-1.0
Conditioned reinforcement - actives0.00.10.20.3-0.30.3-0.40.3-0.3-0.30.30.2-0.40.3-0.2-0.30.30.2-0.3-0.2-0.2-0.1
Conditioned reinforcement - inactives0.20.41.30.6-0.50.4-0.40.6-0.5-0.50.60.6-0.50.5-1.1-0.60.70.6-0.4-0.6-0.7-0.6
Conditioned locomotion3.84.95.52.3-2.32.3-2.32.3-2.3-2.32.32.0-2.02.3-2.3-2.32.12.3-2.1-2.3-2.3-1.5
Patch foraging indifference point 0 sec1.01.93.51.5-1.91.8-1.71.5-1.5-1.51.51.6-1.11.4-1.1-1.31.11.2-0.9-1.1-1.1-0.2
Patch foraging indifference point AUC0.50.71.20.8-0.90.9-0.80.7-0.9-0.90.90.5-0.71.0-0.5-1.00.81.0-0.8-1.0-1.0-1.1
Delay disc. indifference point, 0s delay0.10.10.30.1-0.30.1-0.20.2-0.2-0.20.20.5-0.30.1-0.4-0.20.10.2-0.3-0.2-0.2-0.2
Delay disc. indifference point, 16s delay0.70.81.3-1.11.0-1.01.0-1.21.01.0-1.0-0.80.5-0.91.00.9-0.8-0.90.70.90.90.2
Delay disc. indifference point, 2s delay0.10.10.20.3-0.50.2-0.20.3-0.2-0.20.20.3-0.30.2-0.2-0.20.20.2-0.3-0.2-0.2-0.3
Delay disc. indifference point, 24s delay0.40.40.8-0.50.5-0.60.6-0.60.60.7-0.7-0.90.2-0.70.70.7-0.7-0.80.50.80.80.9
Delay disc. indifference point, 4s delay0.40.41.00.6-0.80.6-0.60.7-0.6-0.50.51.0-1.00.5-0.6-0.50.70.5-1.0-0.5-0.5-0.3
Delay disc. indifference point, 8s delay0.10.10.3-0.60.3-0.50.4-0.40.40.4-0.4-0.20.1-0.40.30.3-0.4-0.30.30.30.2-0.2
Indifference point function ln k0.20.31.7-0.50.2-0.40.3-0.30.50.5-0.5-0.00.3-0.60.30.6-0.4-0.70.50.80.81.3
Indifference point function log k0.20.31.7-0.50.2-0.40.3-0.30.50.5-0.5-0.00.3-0.60.30.6-0.4-0.70.50.80.81.3
Patch foraging total patch changes 0 sec1.12.13.71.6-1.91.8-1.71.6-1.5-1.61.51.8-1.21.5-1.2-1.41.21.3-0.9-1.2-1.2-0.2
Patch foraging total patch changes 12 sec0.40.60.90.8-1.00.9-0.90.7-0.8-0.90.80.6-0.50.9-0.4-0.80.60.8-0.5-0.8-0.8-0.7
Patch foraging total patch changes 18 sec0.60.91.51.0-1.21.2-1.20.8-1.1-1.11.10.9-0.91.0-0.7-1.00.90.9-0.9-0.9-0.8-0.3
Patch foraging total patch changes 24 sec0.61.11.61.2-1.01.1-1.11.0-1.1-1.11.11.2-1.11.0-1.1-1.01.01.0-1.1-1.0-1.0-0.5
Patch foraging total patch changes 6 sec1.62.43.91.8-2.01.9-1.81.6-1.7-1.71.61.7-1.51.6-1.2-1.61.41.4-1.4-1.3-1.3-0.5
Patch foraging time to switch 0 sec0.40.81.5-0.91.2-1.11.0-1.00.91.0-0.9-0.80.7-1.00.60.9-0.7-0.90.60.90.80.5
Patch foraging water rate 0 sec0.20.51.30.7-1.10.9-0.80.8-0.7-0.80.70.5-0.30.8-0.3-0.70.40.7-0.2-0.6-0.6-0.3
Patch foraging water rate 12 sec0.00.10.6-0.2-0.0-0.00.1-0.00.10.2-0.2-0.20.2-0.20.10.3-0.2-0.30.30.40.40.8
Patch foraging water rate 18 sec0.50.71.5-0.70.7-0.80.8-0.70.80.8-0.9-0.90.7-0.90.60.9-0.8-0.90.81.01.01.2
Patch foraging water rate 24 sec0.00.00.1-0.1-0.00.00.0-0.00.0-0.00.0-0.00.00.00.2-0.0-0.10.00.1-0.1-0.0-0.2
Patch foraging water rate 6 sec0.10.11.10.1-0.10.2-0.20.3-0.1-0.10.00.1-0.1-0.1-0.30.10.0-0.20.10.30.31.0
Seeking ratio, delayed vs. immediate footshock0.50.71.7-1.01.2-0.90.8-0.90.80.7-0.7-0.81.3-0.60.70.6-1.0-0.51.10.40.4-0.3
Distance traveled before self-admin0.91.21.9-1.31.4-1.41.4-1.41.21.1-1.1-0.91.4-1.01.11.0-1.1-0.91.20.70.7-0.4
Distance traveled after self-admin0.40.50.8-0.80.9-0.80.7-0.90.70.7-0.7-0.80.9-0.60.60.6-0.5-0.50.60.40.4-0.3
Extensor digitorum longus weight9.838.644.96.4-5.96.3-6.36.4-6.4-6.46.36.4-6.56.2-6.7-6.36.36.2-6.3-6.1-6.1-4.3
Bone: elastic displacement2.42.83.6-1.41.4-1.51.6-1.51.71.7-1.7-1.81.5-1.71.71.7-1.6-1.81.71.81.81.9
Bone: elastic work0.70.91.4-1.11.1-1.21.1-1.11.01.0-1.0-1.20.8-1.00.90.9-0.9-0.90.80.80.80.2
Bone: endosteal estimation0.20.43.2-0.70.8-0.70.6-0.70.40.3-0.30.20.3-0.20.30.1-0.20.10.0-0.3-0.3-1.8
Bone: endosteal perimeter0.10.20.9-0.50.6-0.60.5-0.50.40.3-0.3-0.30.6-0.20.50.2-0.4-0.10.5-0.1-0.1-1.0
Epididymis fat weight0.30.94.50.3-0.60.5-0.60.5-0.8-0.80.90.7-0.81.0-0.9-1.00.71.1-0.9-1.3-1.3-2.1
Delta time in closed arm before/after self-admin0.50.50.80.7-0.90.7-0.70.7-0.7-0.70.70.8-0.80.7-0.7-0.70.70.7-0.7-0.6-0.6-0.4
Delta time in open arm before/after self-admin1.31.32.4-1.11.5-1.41.3-1.21.21.2-1.2-1.41.3-1.10.81.1-1.0-1.01.10.90.80.1
Diff in mean of infusions in LGA sessions0.70.91.3-1.01.1-1.01.1-1.00.91.0-1.0-1.00.8-0.90.70.9-1.0-0.90.70.80.80.7
Delay discount exponential model param0.00.00.20.10.00.1-0.10.1-0.1-0.10.1-0.10.40.1-0.0-0.10.00.10.2-0.1-0.10.0
Extinction: sum of active levers before priming1.21.31.7-1.21.3-1.21.1-1.31.21.2-1.2-1.01.3-1.21.11.2-1.2-1.11.31.11.10.6
Active lever presses in extinction session 60.60.61.0-0.81.0-1.00.8-0.70.80.9-0.8-0.50.9-0.90.30.8-0.6-0.80.90.70.70.2
Bone: final force0.60.93.50.7-0.60.6-0.70.6-0.8-0.80.91.1-0.91.0-0.8-1.00.81.1-0.9-1.2-1.2-1.9
Bone: final moment0.50.92.70.7-0.60.7-0.70.7-0.8-0.90.91.0-0.90.9-0.7-1.00.81.0-0.9-1.1-1.1-1.6
Food consumed during 24 hour testing period0.20.21.20.3-0.30.3-0.30.3-0.4-0.40.40.0-0.20.5-0.3-0.50.40.6-0.4-0.7-0.6-1.1
Glucose1.11.73.9-1.01.0-0.91.0-0.91.11.1-1.2-1.51.5-1.21.21.3-1.3-1.31.71.41.52.0
Heart weight0.00.10.3-0.30.6-0.30.3-0.20.20.2-0.2-0.30.2-0.10.20.1-0.2-0.10.20.10.1-0.3
Delay discount hyperbolic model param0.00.00.30.00.10.1-0.0-0.0-0.0-0.10.1-0.20.50.10.0-0.1-0.10.10.3-0.1-0.10.0
Intermittent access intake day 1-15 change0.00.00.30.2-0.20.2-0.10.0-0.1-0.00.0-0.1-0.60.00.2-0.00.1-0.0-0.40.10.10.3
Intermittent access intake escalation0.00.10.40.2-0.30.2-0.10.0-0.0-0.0-0.0-0.1-0.6-0.00.40.00.1-0.1-0.30.20.20.7
Intermittent access intake escalation 20.30.30.6-0.30.4-0.50.5-0.50.50.6-0.6-0.6-0.2-0.60.70.6-0.3-0.70.00.70.80.7
Intermitt. access day 1 inactive lever presses0.10.31.00.6-0.50.7-0.60.6-0.5-0.40.30.3-1.00.2-0.3-0.20.60.1-0.70.10.11.0
Intermitt. access day 15 inactive lever presses0.10.30.90.6-0.30.5-0.50.7-0.6-0.50.50.7-0.60.4-0.9-0.40.60.4-0.5-0.3-0.40.1
Intermitt. access escalation Index0.40.51.2-0.70.5-0.50.6-0.60.60.6-0.7-0.70.8-0.60.90.7-0.8-0.80.70.80.81.1
Intermittent access day 1 total infusions0.81.22.1-1.10.7-1.01.0-1.11.11.0-1.0-0.91.4-1.11.21.1-1.3-1.11.51.11.11.2
Intermittent access day 15 total infusions0.30.42.0-0.4-0.0-0.20.3-0.50.50.5-0.5-0.40.3-0.50.90.6-0.6-0.70.50.80.91.4
Intermittent access terminal intake (last 3 days)0.10.11.2-0.0-0.30.1-0.0-0.10.20.2-0.2-0.0-0.1-0.30.50.3-0.2-0.40.20.60.61.1
Intermittent access total infusions0.30.41.2-0.50.1-0.40.5-0.50.60.6-0.6-0.40.6-0.60.80.6-0.7-0.70.80.80.81.1
Intermittent access day 1 locomotion0.10.10.4-0.3-0.2-0.00.2-0.30.10.1-0.1-0.40.6-0.10.40.1-0.5-0.10.50.10.20.7
Intermittent access day 15 total locomotion0.40.71.90.9-1.41.0-0.90.8-0.9-0.90.90.6-0.70.9-0.4-0.90.60.9-0.6-0.9-0.8-0.5
Intermittent access total locomotion0.10.20.80.4-0.90.6-0.40.4-0.4-0.40.40.2-0.20.4-0.1-0.30.00.3-0.0-0.2-0.20.8
Intermittent access standard deviation0.20.30.70.6-0.70.6-0.60.7-0.6-0.50.50.5-0.80.5-0.7-0.50.50.5-0.6-0.5-0.5-0.2
Left kidney weight0.10.61.4-0.70.9-0.70.7-0.50.70.7-0.7-1.01.1-0.60.70.7-0.9-0.61.20.60.70.5
Right kidney weight0.10.60.90.7-0.60.8-0.80.9-0.8-0.80.80.4-0.60.9-0.7-0.80.50.8-0.4-0.9-0.8-0.8
Cocaine induced anxiety1.21.82.81.5-1.31.4-1.41.5-1.4-1.41.31.2-1.41.3-1.7-1.31.51.2-1.4-1.1-1.2-0.3
Post-drug Anxiety1.61.72.41.5-1.51.4-1.31.4-1.3-1.31.31.1-1.41.3-1.1-1.31.31.3-1.4-1.2-1.2-0.6
Baseline Anxiety0.50.61.2-0.80.8-0.90.8-0.90.80.8-0.8-0.70.7-0.71.10.7-0.9-0.70.70.60.6-0.2
Tail length2.911.216.3-3.63.3-3.63.7-3.63.43.3-3.3-4.04.0-3.13.63.1-3.5-2.93.82.72.70.8
Length with tail1.67.111.0-3.32.8-3.13.1-3.02.82.6-2.6-3.13.3-2.33.02.3-2.9-2.02.91.71.7-0.8
Length without tail0.10.45.2-0.90.3-0.40.4-0.40.20.00.0-0.10.30.20.3-0.3-0.40.40.0-0.7-0.7-2.3
Times rat made contact with spout1.72.03.9-1.31.3-1.21.2-1.21.31.4-1.4-1.51.2-1.41.21.5-1.3-1.51.31.61.62.0
Lifetime Intake0.00.10.40.1-0.50.2-0.10.1-0.0-0.00.00.3-0.1-0.00.20.0-0.1-0.10.20.20.20.6
Liver weight, left0.10.11.3-0.20.1-0.20.2-0.30.20.1-0.1-0.20.30.00.6-0.0-0.20.10.2-0.2-0.2-1.1
Liver weight, right0.20.30.9-0.70.5-0.50.5-0.60.50.4-0.4-1.00.9-0.30.80.4-0.7-0.30.80.20.2-0.4
Locomotor activity0.10.20.80.4-0.30.4-0.40.6-0.4-0.40.40.3-0.40.4-0.9-0.40.50.4-0.3-0.4-0.5-0.2
Locomotor testing distance0.40.71.5-0.90.6-0.70.7-0.70.80.8-0.8-1.20.8-0.80.80.8-0.9-0.80.90.80.80.9
Locomotor testing rearing0.61.32.6-1.00.8-0.80.9-0.91.01.0-1.0-1.21.1-1.11.31.1-1.1-1.21.31.31.31.6
Locomotion in novel chamber3.84.95.52.3-2.22.2-2.22.2-2.2-2.32.32.2-1.92.3-2.1-2.32.22.3-1.9-2.3-2.3-2.1
Locomotion in novel chamber post-restriction3.76.17.12.5-2.32.4-2.42.3-2.5-2.52.52.6-2.62.5-2.5-2.52.62.5-2.7-2.5-2.5-2.0
Fecal boli incidents, locomotor time 10.20.30.7-0.40.2-0.40.5-0.40.50.4-0.5-0.70.8-0.40.60.5-0.5-0.50.80.50.50.6
Change in fecal boli incidents, locomotor task0.00.00.3-0.00.00.00.00.10.00.0-0.00.10.2-0.1-0.30.1-0.2-0.10.30.10.10.5
Time >=10cm from walls, locomotor time 11.11.11.70.9-1.01.0-0.91.0-1.1-1.11.11.2-0.81.1-1.1-1.10.91.2-0.8-1.2-1.2-1.3
Bouts of movement, locomotor time 11.01.11.81.2-1.11.1-1.11.1-1.1-1.01.01.1-1.40.9-1.4-0.91.10.9-1.3-0.8-0.8-0.1
Total resting periods, locomotor time 11.71.82.71.6-1.41.4-1.51.4-1.4-1.31.31.4-1.61.3-1.6-1.31.41.2-1.5-1.1-1.1-0.5
Rest time, locomotor task time 10.10.20.7-0.20.2-0.00.1-0.10.20.2-0.3-0.50.7-0.30.30.3-0.4-0.40.60.40.50.8
Distance moved, locomotor task time 10.20.20.4-0.50.5-0.60.6-0.50.60.6-0.5-0.2-0.1-0.50.60.5-0.5-0.50.10.50.50.3
Vertical activity count, locomotor time 10.00.10.70.20.00.0-0.00.2-0.1-0.10.10.5-0.80.1-0.1-0.10.20.1-0.6-0.1-0.1-0.2
Time >=10cm from walls, locomotor time 20.91.32.0-1.31.4-1.31.3-1.11.21.2-1.2-1.21.1-1.20.81.2-1.1-1.11.11.11.00.6
Bouts of movement, locomotor time 22.33.76.62.1-1.91.9-2.01.9-1.9-1.81.82.2-2.61.7-2.4-1.72.21.6-2.4-1.5-1.6-0.4
Total resting periods, locomotor time 22.03.55.92.1-1.81.9-1.91.8-1.9-1.81.82.2-2.41.6-2.3-1.72.21.6-2.3-1.4-1.5-0.3
Rest time, locomotor task time 20.10.10.40.0-0.30.5-0.40.5-0.3-0.30.20.40.30.2-0.3-0.10.10.10.30.00.00.6
Distance moved, locomotor task time 20.10.20.3-0.30.5-0.60.5-0.50.50.5-0.4-0.4-0.0-0.40.60.4-0.5-0.30.10.30.3-0.2
Vertical activity count, locomotor time 20.10.10.70.30.2-0.0-0.00.1-0.00.0-0.0-0.0-0.8-0.1-0.20.00.2-0.0-0.70.10.00.1
Light reinforcement 13.58.610.63.3-3.03.2-3.23.1-3.1-3.13.12.5-2.93.0-3.0-3.03.02.9-2.8-2.8-2.8-1.5
Light reinforcement 20.91.42.01.4-1.31.3-1.21.3-1.3-1.21.20.7-1.01.2-1.3-1.21.21.2-1.0-1.1-1.1-0.6
Bone: marrow area0.10.33.2-0.60.7-0.60.6-0.60.30.3-0.20.30.2-0.10.30.0-0.20.1-0.0-0.4-0.4-1.8
Bone: maximum diameter0.10.20.20.3-0.30.4-0.40.5-0.4-0.50.50.5-0.30.5-0.4-0.50.30.5-0.2-0.5-0.5-0.5
Bone: maximum force0.61.15.70.6-0.50.5-0.60.5-0.7-0.80.91.1-0.91.0-0.7-1.00.81.1-1.1-1.3-1.3-2.4
Bone: maximum moment0.61.04.40.6-0.60.6-0.70.6-0.8-0.80.91.1-1.01.0-0.6-1.00.81.1-1.1-1.3-1.3-2.1
Mean time between licks in bursts1.84.45.12.0-2.12.2-2.22.2-2.2-2.22.22.0-2.12.1-2.3-2.12.02.1-2.0-2.1-2.1-1.4
Mean num. licks in bursts0.30.40.80.6-0.40.5-0.60.6-0.6-0.60.60.6-0.60.6-0.9-0.60.50.7-0.6-0.7-0.7-0.6
Cd content in liver5.15.710.1-2.51.9-2.32.4-2.62.42.4-2.4-2.72.4-2.23.22.3-2.6-2.32.42.22.31.4
Co content in liver3.23.74.4-1.91.7-1.81.9-1.81.91.9-2.0-1.91.9-1.92.12.0-2.0-2.01.92.02.11.9
Cu content in liver1.61.82.4-1.31.5-1.61.5-1.41.41.5-1.5-1.21.2-1.51.11.4-1.2-1.41.21.41.41.0
Fe content in liver3.84.65.3-2.22.3-2.22.2-2.12.22.2-2.2-1.92.0-2.21.92.2-2.0-2.22.02.22.21.8
K content in liver3.83.64.92.1-1.61.8-1.81.9-1.9-1.91.92.1-2.01.8-2.2-1.82.11.8-2.0-1.8-1.8-1.3
Mg content in liver0.50.50.80.9-0.60.7-0.70.8-0.7-0.70.70.9-0.90.6-0.8-0.60.90.6-0.9-0.6-0.6-0.2
Mn content in liver0.30.31.00.8-0.50.5-0.50.8-0.5-0.50.50.7-0.50.3-1.0-0.40.70.3-0.3-0.2-0.30.4
Na content in liver0.10.10.40.20.20.0-0.10.3-0.1-0.10.10.5-0.30.0-0.6-0.10.40.1-0.4-0.1-0.10.0
Rb content in liver5.76.68.72.6-2.22.5-2.52.6-2.6-2.62.62.8-2.62.5-2.9-2.62.72.6-2.6-2.5-2.6-1.9
Se content in liver0.20.30.50.7-0.40.5-0.50.7-0.5-0.50.50.7-0.60.5-0.7-0.50.70.5-0.5-0.4-0.5-0.3
Sr content in liver0.00.00.10.1-0.30.2-0.10.1-0.1-0.10.10.2-0.20.1-0.0-0.00.10.0-0.10.00.00.3
Zn content in liver0.00.00.10.0-0.10.00.0-0.10.10.1-0.1-0.0-0.1-0.00.30.0-0.1-0.10.00.10.10.0
Bone: minimum diameter0.50.93.30.5-0.80.7-0.70.7-0.8-0.90.91.0-0.81.0-0.7-1.00.71.1-0.8-1.2-1.2-1.8
Time in familiar zone, hab. session 10.20.20.8-0.20.2-0.20.2-0.20.30.3-0.4-0.60.6-0.40.50.4-0.4-0.50.60.50.60.9
Time in novel zone, hab. session 13.23.24.2-1.91.9-1.91.9-2.01.91.8-1.8-2.11.9-1.71.81.7-1.8-1.71.81.61.60.7
Total zone transitions, hab. session 10.81.12.60.9-0.90.8-0.90.9-0.9-1.01.01.1-1.01.1-1.0-1.11.01.2-1.1-1.2-1.2-1.6
Total locomotion distance, hab. session 11.31.86.60.9-1.10.9-1.00.9-1.1-1.21.31.4-1.01.4-1.0-1.41.11.5-1.1-1.7-1.7-2.6
Locomotion velocity, hab. session 12.53.67.21.5-1.71.6-1.61.5-1.7-1.81.92.2-1.81.9-1.6-2.01.72.0-1.8-2.2-2.2-2.7
Time in familiar zone, hab. session 20.30.31.0-0.30.4-0.40.4-0.20.40.4-0.4-1.00.8-0.40.30.5-0.5-0.50.70.50.50.7
Time in novel zone, hab. session 20.30.30.6-0.60.4-0.40.5-0.70.60.5-0.50.00.3-0.50.80.5-0.5-0.60.40.60.60.5
Total zone transitions, hab. session 20.00.00.1-0.10.1-0.10.0-0.00.00.0-0.10.1-0.2-0.1-0.10.10.0-0.1-0.20.10.10.3
Total locomotion distance, hab. session 20.10.10.90.1-0.20.2-0.20.1-0.3-0.30.30.4-0.30.4-0.3-0.40.20.4-0.3-0.5-0.6-0.9
Locomotion velocity, hab. session 20.30.41.40.3-0.40.4-0.50.4-0.5-0.60.60.6-0.50.6-0.6-0.70.50.7-0.6-0.8-0.8-1.2
Novel to familiar place preference ratio0.91.01.9-1.31.4-1.21.1-1.21.11.0-1.0-0.61.0-1.00.61.0-1.0-0.91.00.90.80.4
Novelty place preference1.21.22.1-1.31.5-1.31.2-1.21.21.1-1.1-0.71.1-1.20.71.1-1.1-1.11.21.01.00.7
Time in novel zone, NPP test1.51.62.6-1.51.6-1.41.4-1.41.31.3-1.3-0.91.3-1.30.91.3-1.3-1.31.31.21.20.9
Total zone transitions, NPP test0.30.40.80.7-0.90.7-0.70.6-0.7-0.70.70.3-0.80.6-0.6-0.60.70.6-0.8-0.6-0.6-0.2
Total locomotion distance, NPP test0.30.31.20.5-0.70.5-0.50.3-0.5-0.60.60.3-0.50.6-0.2-0.60.50.7-0.5-0.7-0.7-1.1
Locomotion velocity, NPP test0.60.91.60.9-1.10.9-0.90.7-0.9-0.91.00.8-0.91.0-0.7-1.00.91.0-0.8-1.1-1.1-1.3
Intraocular pressure0.10.10.3-0.1-0.1-0.10.1-0.30.20.2-0.20.20.2-0.30.60.3-0.3-0.30.30.40.40.5
Delta distance traveled before/after self-admin0.10.10.20.4-0.40.4-0.50.4-0.4-0.30.30.1-0.30.3-0.3-0.30.40.3-0.4-0.2-0.20.0
Delta ambulatory time before/after self-admin0.30.40.60.7-0.70.7-0.80.6-0.6-0.60.60.4-0.60.6-0.7-0.60.80.5-0.7-0.5-0.5-0.3
Parametrial fat weight0.00.10.40.3-0.40.5-0.40.4-0.3-0.30.20.0-0.40.2-0.0-0.2-0.00.1-0.20.00.00.6
Pavlov. Cond. lever latency2.93.75.02.1-2.22.1-2.11.9-2.0-2.12.01.8-1.52.1-1.5-2.01.82.0-1.5-2.0-1.9-1.6
Pavlov. Cond. magazine entry latency2.53.34.4-2.12.0-2.12.1-2.02.02.0-1.9-1.61.7-1.91.71.8-1.7-1.81.51.71.70.7
Pavlov. Cond. change in total contacts2.32.43.7-1.91.8-1.71.7-1.61.61.6-1.6-1.21.4-1.61.31.6-1.6-1.51.41.51.40.9
Pavlov. Cond. index score3.84.86.1-2.52.4-2.42.4-2.22.32.3-2.3-2.01.9-2.32.02.3-2.1-2.31.82.22.21.6
Pavlov. Cond. latency score3.64.55.8-2.42.4-2.42.3-2.22.22.3-2.2-2.01.8-2.21.82.2-2.0-2.21.82.12.11.5
Pavlov. Cond. lever contacts3.13.74.6-2.12.2-2.12.1-1.92.02.0-2.0-1.81.5-2.11.62.0-1.8-2.01.52.02.01.7
Pavlov. Cond. magazine entry number4.05.06.72.6-2.52.6-2.52.4-2.4-2.42.41.9-2.02.4-2.1-2.32.12.2-1.8-2.1-2.1-1.2
Pavlov. Cond. intertrial magazine entries0.00.10.10.2-0.20.3-0.30.2-0.3-0.30.30.2-0.10.3-0.2-0.30.20.3-0.1-0.3-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.3.23.95.0-2.22.2-2.22.2-2.02.12.1-2.1-1.81.7-2.11.72.1-1.9-2.01.62.02.01.4
Pavlov. Cond. response bias3.94.86.3-2.52.5-2.42.4-2.32.32.3-2.3-1.91.9-2.31.92.3-2.1-2.21.82.22.11.5
Pavlov. Cond. lever latency0.10.10.40.5-0.30.3-0.30.3-0.3-0.20.20.4-0.70.2-0.2-0.20.30.1-0.5-0.1-0.10.2
Pavlov. Cond. magazine entry latency0.20.30.7-0.80.4-0.50.5-0.80.60.5-0.5-0.40.7-0.40.90.4-0.7-0.40.50.40.4-0.1
Pavlov. Cond. change in total contacts0.71.12.2-1.31.0-1.01.0-1.21.00.9-0.9-1.21.5-0.91.30.9-1.2-0.81.30.70.70.0
Pavlov. Cond. index score0.20.30.7-0.80.5-0.50.5-0.70.50.4-0.4-0.60.8-0.30.70.3-0.6-0.30.70.20.2-0.4
Pavlov. Cond. latency score0.10.20.4-0.70.3-0.40.3-0.50.30.3-0.2-0.30.7-0.20.60.2-0.5-0.10.5-0.00.0-0.6
Pavlov. Cond. lever contacts0.40.51.2-0.90.7-0.70.7-0.80.70.6-0.6-0.81.1-0.60.70.6-0.8-0.51.00.50.50.1
Pavlov. Cond. magazine entry number0.50.61.11.0-0.60.8-0.81.0-0.7-0.70.70.8-0.90.7-1.0-0.70.90.6-0.7-0.6-0.6-0.0
Pavlov. Cond. intertrial magazine entries0.50.71.51.0-0.60.9-0.91.1-0.8-0.80.80.9-1.10.7-1.2-0.70.90.7-1.0-0.6-0.60.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.60.3-0.30.3-0.50.30.2-0.2-0.30.6-0.20.50.2-0.4-0.10.40.00.1-0.4
Pavlov. Cond. response bias0.30.51.1-0.90.7-0.80.7-0.80.70.6-0.6-0.81.1-0.50.60.5-0.7-0.40.90.30.3-0.3
Time in closed arm before self-admin1.62.03.2-1.61.7-1.51.5-1.61.41.4-1.4-1.61.4-1.31.81.3-1.6-1.21.51.11.20.3
Time in closed arm after self-admin0.10.10.4-0.60.4-0.40.4-0.50.30.3-0.3-0.40.1-0.30.50.3-0.4-0.20.20.20.2-0.4
Time in open arm before self-admin1.01.12.21.1-1.51.2-1.11.2-1.1-1.11.11.2-0.81.0-0.9-1.00.91.0-0.9-0.9-0.8-0.1
Time in open arm after self-admin0.70.81.7-0.91.0-1.11.1-0.90.90.8-0.8-1.11.3-0.80.70.7-0.9-0.61.00.50.5-0.0
Bone: periosteal estimation0.10.33.0-0.20.1-0.1-0.0-0.0-0.1-0.20.30.5-0.20.4-0.1-0.40.10.5-0.3-0.7-0.7-1.7
Bone: periosteal perimeter0.10.10.3-0.50.5-0.40.4-0.40.40.3-0.3-0.30.4-0.20.40.2-0.4-0.20.50.10.1-0.5
Bone: post-yield work0.10.21.9-0.20.0-0.10.0-0.0-0.1-0.10.20.8-0.50.20.0-0.30.30.3-0.7-0.5-0.5-1.4
Progressive ratio test 1 active lever presses0.10.10.30.2-0.50.3-0.30.3-0.2-0.20.20.4-0.10.2-0.1-0.10.00.10.1-0.00.00.4
Progressive ratio test 1 breakpoint0.00.00.20.3-0.40.3-0.30.3-0.2-0.20.20.3-0.00.1-0.1-0.10.00.10.1-0.00.00.3
Progressive ratio test 1 inactive lever presses0.91.32.31.3-1.21.3-1.31.5-1.2-1.21.11.3-1.41.1-1.4-1.11.21.0-1.1-0.9-0.9-0.1
Progressive ratio test 2 active lever presses0.00.00.10.1-0.20.1-0.10.1-0.0-0.00.00.4-0.1-0.00.00.00.0-0.10.10.10.10.2
Progressive ratio test 2 breakpoint0.00.00.20.1-0.10.1-0.10.00.10.0-0.00.3-0.1-0.10.10.1-0.0-0.20.10.20.20.4
Progressive ratio test 2 inactive lever presses0.00.00.30.2-0.30.2-0.10.2-0.1-0.00.00.2-0.1-0.0-0.00.00.1-0.10.00.10.10.5
Incentive Sensitization - Responses0.20.30.5-0.50.6-0.60.6-0.60.60.6-0.6-0.30.6-0.60.70.6-0.5-0.60.60.60.60.5
Incentive Sensitization - Breakpoint0.20.30.5-0.40.5-0.50.5-0.60.50.5-0.5-0.20.4-0.50.70.5-0.5-0.50.50.50.60.5
Sum of active levers in priming session hrs 5-61.41.32.3-1.31.5-1.51.3-1.31.21.2-1.2-1.21.2-1.20.81.1-1.1-1.01.00.90.90.0
Progressive ratio0.71.11.51.1-1.21.0-1.00.9-1.0-1.01.00.9-1.11.0-0.6-1.01.01.0-1.1-1.1-1.0-1.2
Food seeking constrained by brief footshock0.60.72.10.8-0.80.7-0.80.8-0.8-0.80.80.7-0.60.9-0.5-0.90.70.9-0.5-0.9-0.9-1.5
Seeking ratio, punishment vs. effort0.10.10.30.3-0.00.2-0.20.4-0.3-0.30.30.3-0.10.3-0.6-0.30.30.4-0.2-0.4-0.4-0.5
Retroperitoneal fat weight0.62.74.01.4-1.41.6-1.61.7-1.6-1.61.62.0-1.91.6-2.0-1.61.61.6-1.8-1.6-1.6-1.3
Reaction time number correct0.71.31.91.2-1.01.3-1.41.3-1.2-1.31.20.9-0.91.2-1.2-1.21.01.1-0.9-1.1-1.1-0.5
Reaction time mean minus median0.71.72.4-1.41.4-1.61.5-1.51.41.4-1.4-1.31.3-1.31.31.3-1.3-1.21.21.11.10.3
Reaction time mean minus median AUC0.71.72.2-1.41.3-1.51.4-1.41.41.4-1.4-1.51.4-1.31.31.3-1.2-1.21.21.21.20.5
Reaction time num false alarms3.34.67.12.5-2.72.4-2.42.2-2.3-2.32.21.8-2.12.2-2.0-2.22.22.1-2.0-2.0-2.0-1.0
Reaction time num false alarms AUC4.16.48.82.9-3.02.7-2.72.5-2.7-2.62.62.1-2.52.6-2.5-2.62.62.5-2.3-2.4-2.4-1.4
Reaction time trials correct on left0.71.31.91.2-1.01.3-1.41.3-1.2-1.31.20.9-0.91.2-1.2-1.21.01.1-0.9-1.1-1.1-0.5
Reaction time trials on left0.61.21.81.1-1.01.3-1.31.3-1.2-1.21.20.9-0.81.2-1.2-1.11.01.1-0.9-1.1-1.1-0.5
Reaction time mean3.15.07.8-2.42.8-2.82.6-2.52.42.5-2.4-2.21.9-2.41.92.3-1.9-2.11.62.01.90.7
Reaction time mean AUC2.84.46.9-2.32.6-2.62.5-2.42.32.3-2.3-2.11.8-2.21.72.2-1.8-2.01.51.91.80.8
Median of all reaction times3.65.18.6-2.42.9-2.82.7-2.62.52.5-2.4-2.31.8-2.41.82.3-1.9-2.21.62.02.00.9
Reaction time omissions1.11.72.2-1.01.1-1.21.3-1.41.31.3-1.3-1.51.2-1.31.41.3-1.2-1.31.21.41.41.3
Reaction time false alarm rate1.92.74.21.9-2.01.7-1.71.6-1.7-1.71.61.5-1.71.6-1.6-1.61.81.6-1.6-1.5-1.5-0.8
Reaction time premature initiation rate0.10.10.2-0.30.3-0.30.3-0.30.40.4-0.4-0.2-0.1-0.40.40.3-0.2-0.4-0.00.40.40.3
Reaction time premature initiations0.00.10.10.3-0.20.3-0.30.3-0.2-0.30.20.3-0.40.2-0.3-0.20.20.2-0.4-0.2-0.20.0
Std. dev. reaction times2.54.76.7-2.42.4-2.62.5-2.52.32.3-2.3-2.12.1-2.22.12.2-2.1-2.01.91.91.90.5
Reaction time trials completed0.61.21.81.1-1.01.3-1.31.3-1.2-1.21.20.9-0.81.2-1.2-1.11.01.1-0.9-1.1-1.1-0.5
Reaction time trials AUC0.51.01.61.0-1.01.2-1.21.2-1.1-1.11.10.8-0.81.1-1.1-1.00.91.0-0.8-1.0-1.0-0.4
Run reversals in cocaine runway, females1.11.11.81.1-1.20.8-0.91.0-1.0-1.01.10.9-0.81.0-1.3-1.11.01.2-0.7-1.2-1.3-1.2
Run reversals in cocaine runway, males1.01.01.41.2-1.11.1-1.11.1-1.1-1.01.00.3-1.21.1-0.9-1.01.01.0-1.1-1.0-1.0-0.6
Latency to leave start box in cocaine runway3.64.16.12.2-2.42.3-2.22.2-2.1-2.02.01.9-2.52.0-1.9-2.02.01.8-2.2-1.7-1.7-0.7
Latency to leave start box in cocaine runway, F1.31.52.71.5-1.61.5-1.41.4-1.3-1.31.20.9-1.51.2-1.1-1.11.21.0-1.3-0.9-0.80.2
Latency to leave start box in cocaine runway, M4.23.94.81.9-2.02.0-2.02.0-2.0-2.02.02.2-2.12.0-1.9-2.02.02.0-2.0-2.0-2.0-1.7
Std. dev. time between licks in bursts3.04.05.42.3-2.32.2-2.22.3-2.1-2.12.02.0-2.31.9-2.0-1.92.01.8-2.1-1.6-1.6-0.4
Total sessions with >9 infusions2.63.25.21.8-2.31.9-1.91.8-1.8-1.91.92.0-1.61.9-1.7-1.81.61.8-1.4-1.8-1.7-1.3
Short access day 1 total inactive lever presses2.83.65.61.9-2.42.0-2.02.0-1.9-2.01.91.9-1.62.0-1.4-2.01.82.0-1.7-2.0-1.9-1.7
Short access day 10 total inactive lever presses0.10.20.50.50.00.3-0.30.4-0.3-0.30.30.3-0.70.3-0.4-0.30.60.3-0.7-0.3-0.3-0.2
Short access day 1 total infusions3.04.05.51.9-2.31.9-2.12.0-2.0-2.02.02.3-1.52.0-2.0-2.02.02.0-1.6-2.0-2.0-2.1
Short access day 10 total infusions0.20.22.1-0.2-0.1-0.10.1-0.10.30.3-0.3-0.10.1-0.50.30.5-0.4-0.60.40.70.71.4
Short access total infusions0.20.30.80.5-0.90.6-0.60.6-0.5-0.50.50.9-0.50.5-0.5-0.50.40.4-0.3-0.3-0.30.0
Short access day 1 locomotion3.54.44.92.0-2.22.1-2.22.1-2.1-2.22.22.1-1.82.2-2.2-2.21.92.2-1.8-2.2-2.2-1.9
Short access day 10 total locomotion0.10.20.70.4-0.80.7-0.60.5-0.5-0.60.50.0-0.40.60.0-0.50.20.5-0.4-0.5-0.40.1
Short access total locomotion2.42.95.01.7-2.21.9-1.81.8-1.8-1.81.81.6-1.41.8-1.6-1.81.51.8-1.5-1.7-1.7-0.9
One hour access (0.3 mA shock)0.30.30.5-0.50.5-0.50.4-0.70.60.6-0.6-0.40.3-0.60.70.6-0.5-0.60.50.70.70.6
Compulsive drug intake1.01.21.81.1-1.11.2-1.21.1-1.1-1.11.10.9-1.21.1-0.9-1.11.11.1-1.3-1.0-1.0-0.9
One hour access (shock baseline)0.60.91.4-0.80.7-0.80.9-1.01.00.9-0.9-0.70.9-0.91.21.0-0.9-1.01.01.01.00.9
Social response proportion0.40.40.6-0.50.8-0.80.7-0.60.70.7-0.7-0.80.7-0.70.50.7-0.5-0.60.60.60.60.4
Social responses0.00.00.20.1-0.40.2-0.1-0.0-0.1-0.10.1-0.5-0.10.20.3-0.10.00.1-0.0-0.2-0.1-0.2
Social time1.82.53.9-1.51.5-1.61.6-1.61.61.6-1.6-2.01.5-1.61.51.6-1.4-1.61.51.61.61.5
Soleus weight1.74.96.02.0-2.12.2-2.22.1-2.2-2.22.22.5-2.42.3-2.1-2.32.02.3-2.3-2.3-2.3-2.1
Bone: stiffness1.11.87.20.9-0.80.8-0.90.8-1.1-1.21.21.5-1.11.3-1.0-1.41.21.5-1.3-1.7-1.7-2.7
Tibialis anterior weight4.314.619.13.9-3.64.0-4.04.1-4.0-3.93.94.4-4.23.8-4.2-3.83.83.7-3.9-3.5-3.6-2.1
Time to tail flick, vehicle, before self-admin0.10.10.8-0.30.3-0.10.2-0.30.30.3-0.3-0.40.0-0.30.60.3-0.5-0.40.20.40.50.9
Time to tail flick, vehicle, after self-admin0.91.11.7-1.21.3-1.01.1-1.01.01.1-1.1-0.80.8-1.10.91.1-1.0-1.10.71.11.11.2
Time to tail flick, test, before self-admin3.13.24.41.9-1.61.8-1.91.7-1.8-1.81.81.7-2.01.8-1.7-1.81.91.7-2.1-1.7-1.7-1.3
Time to tail flick, test, after self-admin3.43.54.31.9-1.71.9-1.91.9-2.0-1.91.91.5-2.01.9-1.9-1.92.01.9-2.1-1.9-1.9-1.3
Delta time to tail flick, vehicle, before/after SA0.30.30.4-0.60.6-0.60.6-0.50.50.6-0.6-0.20.5-0.60.20.5-0.4-0.50.40.50.50.3
Delta time to tail flick, test, before/after SA0.20.20.4-0.50.4-0.30.4-0.30.40.4-0.4-0.60.3-0.30.50.3-0.5-0.30.50.30.30.4
Tibia length0.30.74.9-1.11.1-1.10.9-1.00.70.5-0.4-0.40.9-0.30.60.2-0.6-0.00.5-0.3-0.3-2.2
Ambulatory time before self-admin1.21.82.6-1.61.6-1.61.5-1.61.41.4-1.3-1.11.6-1.21.41.2-1.4-1.11.51.01.0-0.2
Ambulatory time after self-admin0.40.40.7-0.80.7-0.70.7-0.80.70.7-0.7-0.70.9-0.60.60.6-0.5-0.60.70.50.50.0
Bone: tissue strength0.00.00.2-0.1-0.1-0.10.2-0.20.20.1-0.1-0.30.1-0.10.40.1-0.2-0.10.20.10.1-0.1
Total heroin consumption1.71.92.6-1.31.6-1.51.5-1.41.41.5-1.5-1.31.0-1.51.01.5-1.3-1.51.21.51.51.2
Bone: trabecular number1.01.72.6-1.51.1-1.41.4-1.41.41.3-1.3-1.41.6-1.21.41.2-1.5-1.21.61.11.10.5
Bone: trabecular spacing1.21.72.21.3-0.91.1-1.21.3-1.3-1.21.21.4-1.41.2-1.5-1.31.51.3-1.5-1.3-1.3-1.1
Bone: trabecular thickness6.88.510.5-3.12.8-2.92.9-3.03.02.9-2.9-2.93.1-2.93.22.9-3.0-2.93.02.82.82.0
Bone: trabecular tissue density0.10.10.6-0.20.10.0-0.10.0-0.1-0.20.20.60.00.2-0.1-0.20.10.3-0.1-0.3-0.3-0.8
Water consumed over 24 hours0.00.10.4-0.1-0.10.1-0.0-0.10.10.1-0.1-0.20.1-0.10.40.2-0.2-0.20.10.30.30.6
Number of responses in last shaping day0.00.00.2-0.10.3-0.10.10.00.10.1-0.1-0.1-0.1-0.1-0.30.1-0.0-0.1-0.20.20.10.5