Wdr75

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Wdr75 0.37 0.17 0.0e+00 0.3 0.27 0.31 0.3 1.2e-16 5.4e-15 5.1e-17 1.1e-16
2 RMTg mRNA stability Wdr75 0.15 0.1 1.8e-03 0.07 0.05 0.04 0.05 6.0e-03 1.4e-02 3.9e-02 1.6e-02
3 Adipose mRNA stability Wdr75 0.28 0.13 0.0e+00 0.12 0.12 0.12 0.12 1.7e-13 6.6e-13 1.7e-13 1.3e-13
4 Liver gene expression Wdr75 0.06 0.04 2.1e-07 0.02 0.02 0.01 0.01 9.6e-04 1.3e-03 1.2e-02 1.0e-02
5 Brain mRNA stability Wdr75 0.18 0.09 0.0e+00 0.2 0.2 0.2 0.2 1.9e-18 1.6e-18 3.8e-18 1.5e-18
6 NAcc mRNA stability Wdr75 0.05 0.03 1.3e-06 0.05 0.05 0.04 0.05 1.5e-06 1.6e-06 3.7e-05 2.5e-06
7 PL mRNA stability Wdr75 0.07 0.04 2.2e-09 0.07 0.08 0.07 0.07 6.5e-08 4.0e-09 2.5e-08 1.4e-08
8 Adipose gene expression Wdr75 0.2 0.1 0.0e+00 0.11 0.12 0.1 0.11 5.1e-12 7.2e-13 1.5e-11 2.0e-12
9 NAcc gene expression Wdr75 0.25 0.15 0.0e+00 0.16 0.16 0.16 0.16 2.8e-18 1.5e-18 1.4e-18 9.9e-19
10 Brain gene expression Wdr75 0.21 0.1 0.0e+00 0.23 0.24 0.24 0.24 2.2e-21 1.7e-22 5.1e-22 9.9e-22
11 PL gene expression Wdr75 0.54 0.11 0.0e+00 0.3 0.32 0.31 0.3 8.8e-33 1.9e-36 6.8e-35 6.6e-33
12 Liver mRNA stability Wdr75 0.05 0.04 4.5e-06 0.02 0.03 0.02 0.02 1.0e-03 3.1e-04 1.2e-03 9.7e-04
13 IL gene expression Wdr75 0.44 0.19 1.7e-06 0.16 0.14 0.12 0.11 1.5e-04 2.5e-04 7.1e-04 1.3e-03
14 OFC gene expression Wdr75 0.55 0.17 1.1e-08 0.23 0.18 0.16 0.21 4.2e-06 4.8e-05 1.1e-04 1.3e-05
15 RMTg gene expression Wdr75 0.18 0.11 6.2e-04 0.06 0.08 0.02 0.07 8.5e-03 3.6e-03 8.8e-02 6.9e-03
16 pVTA mRNA stability Wdr75 0.13 0.11 2.1e-03 0.02 0.04 0.04 0.04 5.3e-02 6.1e-03 1.2e-02 1.0e-02
17 BLA mRNA stability Wdr75 0.04 0.04 7.9e-03 0.02 0.01 0 0.01 4.2e-02 1.4e-01 2.7e-01 1.4e-01
18 pVTA gene expression Wdr75 0.11 0.09 6.3e-03 0.03 0.02 0.03 0.03 2.9e-02 3.0e-02 2.3e-02 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density2.33.84.8-2.11.9-2.2-2.2-2.12.2-2.02.02.01.92.1-1.9-1.9-1.91.8-1.61.9-1.2
Area under the delay curve0.10.10.2-0.30.3-0.3-0.3-0.40.3-0.40.40.10.40.3-0.4-0.0-0.00.4-0.4-0.2-0.0
BMI with tail1.86.09.03.0-3.02.62.82.8-2.82.5-2.5-2.7-2.3-2.22.12.62.6-1.91.6-2.20.5
BMI without tail0.10.21.01.0-0.80.20.30.2-0.30.2-0.2-0.2-0.10.20.00.1-0.10.2-0.20.2-0.9
Body weight0.10.20.50.5-0.70.40.50.4-0.50.5-0.5-0.4-0.5-0.30.50.40.4-0.50.5-0.30.5
Weight adjusted by age1.82.04.40.9-0.81.31.21.3-1.21.4-1.4-1.4-1.5-1.71.51.41.4-1.71.6-1.52.1
Bone surface0.00.10.8-0.3-0.0-0.2-0.2-0.00.20.1-0.10.0-0.20.10.20.10.1-0.40.5-0.10.9
Bone volume0.61.01.9-1.41.0-1.2-1.2-1.11.2-1.01.01.00.91.1-0.8-0.9-0.90.7-0.50.90.1
Breakpoint value in progressive ratio session0.40.41.0-1.01.0-0.6-0.5-0.60.5-0.70.70.70.70.0-0.6-0.6-0.60.5-0.60.5-0.2
Number of licking bursts2.22.65.7-0.81.5-1.3-1.3-1.41.3-1.41.51.71.51.6-1.6-1.8-1.91.7-1.71.9-2.4
Context. condit. distance diff. score0.70.83.1-0.30.7-0.5-0.5-0.60.5-0.90.90.61.10.4-1.1-0.6-0.51.3-1.50.7-1.8
Locomotion velocity, session 10.10.10.2-0.3-0.4-0.3-0.3-0.30.3-0.30.30.10.30.5-0.30.1-0.20.3-0.30.3-0.4
Locomotion distance, session 10.30.40.90.5-0.60.70.70.9-0.70.7-0.7-0.6-0.7-0.70.70.60.6-0.70.6-0.50.4
Locomotion velocity, session 21.41.64.21.4-2.01.31.31.4-1.31.4-1.4-1.1-1.4-0.91.41.00.8-1.31.3-0.90.6
Locomotion distance, session 21.21.62.41.3-1.51.21.31.5-1.31.4-1.4-1.2-1.4-1.11.41.11.0-1.41.4-1.00.9
Locomotion velocity, session 30.10.10.50.5-0.70.30.20.3-0.20.2-0.2-0.3-0.2-0.30.10.30.1-0.10.1-0.2-0.2
Locomotion distance, session 30.10.10.50.30.2-0.0-0.1-0.00.1-0.20.20.10.30.1-0.3-0.1-0.10.4-0.50.0-0.7
Stereotopy head waving bouts, day 30.50.61.30.9-1.20.60.80.7-0.80.7-0.7-0.9-0.6-0.60.60.90.8-0.60.6-0.80.6
Stereotopy head waving duration, day 30.00.00.20.1-0.5-0.10.1-0.1-0.1-0.00.0-0.20.00.2-0.00.20.20.1-0.0-0.20.1
Locomotion velocity, session 71.92.13.11.4-1.51.41.31.3-1.31.5-1.4-1.4-1.5-1.31.51.41.4-1.61.6-1.51.8
Locomotion distance, session 71.41.82.41.4-1.51.41.31.2-1.31.3-1.3-1.3-1.4-1.31.41.31.4-1.41.4-1.31.4
Stereotopy head waving bouts, day 70.30.40.6-0.60.8-0.7-0.6-0.60.6-0.70.70.60.70.5-0.7-0.6-0.50.6-0.70.5-0.5
Stereotopy head waving duration, day 70.60.71.1-0.91.0-1.0-0.9-0.80.9-0.90.90.90.80.8-0.8-1.0-1.00.7-0.70.8-0.5
Locomotion velocity, session 80.00.10.40.1-0.00.00.1-0.0-0.1-0.10.10.20.2-0.1-0.2-0.2-0.20.3-0.40.2-0.7
Locomotion distance, session 80.20.20.50.7-0.70.50.60.7-0.60.4-0.4-0.5-0.2-0.60.20.50.5-0.1-0.1-0.2-0.6
Degree of sensitization distance1.21.23.00.8-1.20.90.90.8-0.91.0-1.0-1.0-1.2-0.81.21.21.2-1.31.4-1.01.7
Degree of sensitization stereotypy0.60.71.3-0.81.1-0.9-0.8-0.70.8-0.80.80.80.80.6-0.8-0.8-0.80.8-0.80.8-0.8
Conditioned locomotion0.10.10.2-0.20.0-0.4-0.4-0.40.3-0.40.40.10.40.4-0.4-0.00.00.4-0.40.1-0.1
Cocaine response after cond. corrected1.31.52.40.9-1.11.01.11.2-1.11.2-1.3-1.1-1.3-1.11.31.11.3-1.41.5-1.21.6
Cocaine response after cond. not corrected1.41.54.70.7-0.80.90.91.0-0.91.1-1.2-1.1-1.3-1.01.41.11.3-1.51.6-1.42.2
Cocaine response before conditioning0.10.10.9-0.20.30.0-0.0-0.10.00.0-0.0-0.1-0.1-0.20.20.20.2-0.30.4-0.41.0
Saline control response0.30.40.9-0.70.7-0.5-0.5-0.30.5-0.50.50.50.60.2-0.6-0.6-0.70.7-0.80.6-0.9
Bone: connectivity density0.20.30.4-0.50.6-0.6-0.6-0.60.6-0.60.60.60.50.6-0.5-0.6-0.70.5-0.50.6-0.3
Bone: cortical apparent density4.76.28.32.8-2.82.82.82.9-2.82.7-2.7-2.5-2.5-2.72.52.22.2-2.32.1-2.01.0
Bone: cortical area0.81.32.20.8-1.41.01.01.1-1.01.2-1.2-1.0-1.2-0.91.31.01.0-1.31.4-1.11.5
Bone: cortical porosity0.91.01.7-1.31.2-1.0-1.1-1.11.1-1.11.10.91.00.7-1.0-0.8-0.80.9-0.90.8-0.4
Bone: cortical porosity0.60.71.5-1.21.1-1.0-1.0-0.91.0-0.90.90.70.90.6-0.8-0.6-0.50.7-0.70.40.1
Bone: cortical thickness1.01.73.01.4-1.71.31.41.5-1.41.4-1.4-1.3-1.3-1.21.31.21.3-1.21.1-1.20.7
Bone: cortical thickness0.10.10.30.2-0.50.30.30.3-0.30.4-0.4-0.3-0.4-0.40.40.20.1-0.50.5-0.10.4
Bone: cortical tissue density4.76.28.22.8-2.82.82.82.9-2.82.7-2.7-2.4-2.5-2.72.52.22.1-2.32.1-1.91.0
Condit. Reinf. active minus inactive responses3.03.45.6-2.41.6-2.2-2.2-2.02.2-2.02.01.81.91.9-1.8-1.7-1.61.6-1.51.4-0.6
Condit. Reinf. active-inactive response ratio1.92.03.1-1.81.3-1.6-1.7-1.51.7-1.51.51.41.51.4-1.4-1.3-1.21.3-1.21.1-0.5
Condit. Reinf. active responses1.41.73.4-1.91.1-1.7-1.7-1.51.7-1.41.41.21.31.6-1.2-1.0-0.91.0-0.90.70.2
Condit. Reinf. inactive responses0.20.20.90.1-0.40.10.20.4-0.20.4-0.4-0.5-0.50.00.50.70.6-0.50.6-0.71.0
Incentive salience index mean2.83.45.5-2.31.6-2.1-2.2-2.02.2-2.02.01.81.91.8-1.9-1.6-1.71.7-1.61.5-0.8
Condit. Reinf. lever presses1.41.92.3-1.51.2-1.5-1.5-1.41.5-1.51.51.21.51.2-1.5-1.2-1.31.5-1.51.1-1.1
Condit. Reinf. active minus inactive responses1.21.43.3-1.71.8-1.3-1.3-1.31.2-1.21.21.41.00.8-1.0-1.5-1.30.8-0.70.90.1
Condit. Reinf. active-inactive response ratio2.02.15.3-1.62.3-1.5-1.5-1.61.4-1.51.51.61.41.2-1.3-1.7-1.51.2-1.21.0-0.4
Condit. Reinf. active responses0.10.10.6-0.80.6-0.4-0.4-0.30.3-0.20.20.30.1-0.1-0.1-0.3-0.5-0.10.10.30.5
Condit. Reinf. inactive responses0.60.71.10.3-1.10.70.71.0-0.70.9-0.9-0.9-1.0-1.01.01.00.6-1.01.0-0.50.8
Condit. Reinf. lever presses0.00.00.2-0.20.1-0.1-0.10.00.10.0-0.00.2-0.1-0.00.1-0.2-0.4-0.10.20.20.1
Condit. Reinf. lever reinforcers received0.10.10.4-0.60.3-0.2-0.2-0.10.2-0.00.00.2-0.1-0.20.1-0.2-0.5-0.30.30.20.6
Conditioned reinforcement - actives0.20.20.4-0.20.2-0.5-0.6-0.50.6-0.40.40.60.40.7-0.4-0.5-0.50.4-0.30.4-0.1
Conditioned reinforcement - inactives0.00.00.1-0.10.4-0.10.0-0.1-0.0-0.10.10.30.1-0.30.0-0.3-0.3-0.10.10.20.3
Conditioned locomotion4.35.27.92.4-2.82.32.32.4-2.32.4-2.4-2.2-2.4-2.02.42.22.2-2.32.3-1.91.5
Patch foraging indifference point 0 sec1.32.24.42.1-1.91.71.71.7-1.71.6-1.6-1.3-1.5-1.31.41.11.1-1.31.2-0.90.1
Patch foraging indifference point AUC0.80.91.30.9-0.90.90.80.8-0.91.0-1.0-1.0-1.0-0.81.01.11.0-1.01.1-0.91.1
Delay disc. indifference point, 0s delay0.00.00.00.00.0-0.1-0.1-0.10.1-0.10.2-0.10.2-0.1-0.20.20.10.1-0.20.1-0.1
Delay disc. indifference point, 16s delay0.70.81.1-1.01.0-1.0-1.0-0.91.0-0.90.90.80.91.0-0.9-0.8-0.70.8-0.80.3-0.3
Delay disc. indifference point, 2s delay0.00.00.10.3-0.20.10.2-0.0-0.20.1-0.0-0.1-0.1-0.00.10.20.2-0.10.10.10.1
Delay disc. indifference point, 24s delay0.50.50.9-0.60.8-0.7-0.7-0.70.7-0.80.80.60.80.7-0.8-0.6-0.60.9-0.90.1-0.8
Delay disc. indifference point, 4s delay0.40.40.90.9-0.80.60.60.5-0.60.5-0.4-0.9-0.4-0.60.40.90.9-0.40.3-0.40.4
Delay disc. indifference point, 8s delay0.20.20.4-0.60.6-0.5-0.4-0.50.4-0.50.50.50.40.4-0.4-0.5-0.50.4-0.30.00.0
Indifference point function ln k0.30.41.6-0.20.4-0.4-0.4-0.40.4-0.60.60.40.70.4-0.8-0.5-0.50.9-1.00.4-1.3
Indifference point function log k0.30.41.6-0.20.4-0.4-0.4-0.40.4-0.60.60.40.70.4-0.8-0.5-0.50.9-1.00.4-1.3
Patch foraging total patch changes 0 sec1.52.44.52.1-2.01.71.81.8-1.81.7-1.7-1.4-1.6-1.41.51.21.2-1.31.2-1.00.1
Patch foraging total patch changes 12 sec0.50.70.90.9-0.90.80.90.8-0.90.9-0.9-0.7-0.9-0.60.90.70.8-0.90.9-0.70.7
Patch foraging total patch changes 18 sec0.91.12.01.2-1.41.01.01.1-1.11.1-1.1-1.1-1.1-0.81.01.11.2-0.90.9-0.80.5
Patch foraging total patch changes 24 sec0.91.11.61.0-0.51.21.11.1-1.11.1-1.1-1.1-1.0-1.21.01.21.1-1.00.9-0.90.7
Patch foraging total patch changes 6 sec1.52.34.52.1-1.91.71.71.6-1.71.6-1.6-1.4-1.5-1.31.51.31.3-1.31.3-1.20.4
Patch foraging time to switch 0 sec0.60.91.8-1.31.1-1.0-1.0-0.91.0-1.01.01.01.00.7-0.9-1.0-0.80.8-0.90.7-0.4
Patch foraging water rate 0 sec0.60.92.71.6-1.41.01.10.8-1.11.0-0.9-0.9-0.9-0.60.90.80.7-0.80.8-0.50.1
Patch foraging water rate 12 sec0.10.10.60.00.5-0.2-0.2-0.10.1-0.20.30.20.30.3-0.4-0.3-0.20.5-0.50.2-0.8
Patch foraging water rate 18 sec0.60.81.5-0.51.0-0.8-0.7-0.90.7-0.90.90.91.00.9-1.0-0.8-0.81.1-1.10.9-1.2
Patch foraging water rate 24 sec0.00.00.30.30.5-0.1-0.1-0.10.0-0.00.0-0.10.00.3-0.00.1-0.00.00.0-0.00.0
Patch foraging water rate 6 sec0.10.10.80.20.40.20.30.1-0.3-0.10.1-0.10.2-0.2-0.2-0.1-0.10.4-0.50.2-0.9
Seeking ratio, delayed vs. immediate footshock0.70.81.6-1.20.5-1.0-0.9-0.80.9-0.80.81.10.70.8-0.6-1.2-1.20.5-0.41.3-0.3
Distance traveled before self-admin0.40.41.1-1.00.8-0.8-0.8-0.70.8-0.50.50.70.30.6-0.2-0.7-0.7-0.00.20.60.9
Distance traveled after self-admin0.10.10.3-0.30.2-0.1-0.1-0.20.10.0-0.00.2-0.1-0.30.2-0.2-0.2-0.30.30.30.6
Extensor digitorum longus weight10.240.145.06.0-6.26.56.56.6-6.56.4-6.4-6.6-6.3-6.76.36.46.6-6.26.0-6.35.3
Bone: elastic displacement2.02.33.8-1.11.4-1.3-1.4-1.41.4-1.51.51.51.51.4-1.6-1.7-1.71.6-1.71.7-1.9
Bone: elastic work0.50.71.2-0.90.9-0.9-1.1-1.01.1-0.90.90.70.80.8-0.7-0.6-0.70.6-0.60.6-0.0
Bone: endosteal estimation0.20.43.3-1.10.6-0.6-0.7-0.60.7-0.30.30.30.00.40.1-0.0-0.0-0.40.6-0.21.8
Bone: endosteal perimeter0.10.20.8-0.70.3-0.5-0.5-0.50.5-0.30.20.40.10.5-0.0-0.4-0.4-0.10.30.20.9
Epididymis fat weight0.10.21.4-0.2-0.10.10.10.1-0.10.2-0.2-0.3-0.3-0.40.40.40.3-0.50.5-0.41.2
Delta time in closed arm before/after self-admin1.61.52.01.3-1.31.31.21.3-1.21.2-1.2-1.4-1.2-1.01.21.31.3-1.21.2-1.41.1
Delta time in open arm before/after self-admin2.42.33.2-1.61.8-1.6-1.6-1.71.6-1.61.61.61.51.2-1.4-1.6-1.61.3-1.31.6-0.9
Diff in mean of infusions in LGA sessions1.31.42.7-1.51.6-1.2-1.3-1.21.3-1.31.31.11.30.7-1.2-1.1-1.11.1-1.21.0-0.7
Delay discount exponential model param0.10.10.30.3-0.40.40.30.4-0.30.4-0.5-0.1-0.5-0.30.50.10.1-0.50.50.10.2
Extinction: sum of active levers before priming0.60.61.3-1.11.0-0.9-0.8-0.90.8-0.80.80.90.70.4-0.7-0.9-0.90.6-0.50.9-0.2
Active lever presses in extinction session 60.60.61.2-0.91.1-0.7-0.6-0.70.6-0.80.80.80.80.1-0.8-0.8-0.80.8-0.90.8-0.6
Bone: final force0.91.44.70.5-0.80.80.70.9-0.71.1-1.1-1.2-1.2-0.91.31.31.2-1.51.6-1.22.2
Bone: final moment0.81.43.90.6-0.90.80.70.9-0.71.1-1.1-1.2-1.2-0.81.31.41.2-1.41.5-1.22.0
Food consumed during 24 hour testing period0.30.31.40.2-0.80.30.30.1-0.30.4-0.4-0.6-0.5-0.20.50.70.7-0.60.7-0.71.2
Glucose0.71.03.7-0.50.9-0.6-0.7-0.70.6-0.80.80.90.90.7-1.0-1.0-1.21.1-1.21.3-1.9
Heart weight0.00.00.4-0.60.3-0.1-0.1-0.10.2-0.10.10.10.1-0.0-0.0-0.0-0.1-0.00.1-0.10.4
Delay discount hyperbolic model param0.00.00.10.0-0.10.1-0.00.20.00.2-0.20.1-0.20.00.2-0.2-0.2-0.20.20.2-0.0
Intermittent access intake day 1-15 change0.10.10.60.3-0.10.00.0-0.1-0.0-0.10.1-0.30.10.2-0.20.40.40.2-0.3-0.80.0
Intermittent access intake escalation0.20.20.4-0.10.4-0.4-0.4-0.50.4-0.50.50.10.50.7-0.5-0.00.00.6-0.6-0.4-0.2
Intermittent access intake escalation 20.40.40.8-0.20.7-0.6-0.6-0.70.6-0.70.80.20.80.7-0.8-0.2-0.10.8-0.9-0.2-0.3
Intermitt. access day 1 inactive lever presses0.20.20.91.0-0.20.40.40.3-0.40.3-0.3-0.5-0.3-0.20.30.50.5-0.20.2-0.40.3
Intermitt. access day 15 inactive lever presses0.10.10.3-0.20.5-0.2-0.1-0.20.1-0.30.30.20.3-0.3-0.3-0.3-0.30.2-0.30.3-0.0
Intermitt. access escalation Index0.10.10.60.4-0.2-0.10.0-0.0-0.0-0.10.1-0.10.20.5-0.20.10.10.3-0.30.4-0.8
Intermittent access day 1 total infusions1.41.63.1-0.61.1-1.2-1.2-1.11.2-1.21.21.51.21.1-1.2-1.6-1.61.2-1.21.8-1.4
Intermittent access day 15 total infusions1.21.31.8-0.31.0-1.2-1.0-1.11.0-1.21.21.11.31.2-1.3-1.1-1.11.3-1.41.1-1.3
Intermittent access terminal intake (last 3 days)0.50.61.10.00.6-0.8-0.6-0.70.6-0.80.80.70.90.8-0.9-0.7-0.71.0-1.00.6-0.9
Intermittent access total infusions1.01.11.6-0.40.8-1.0-0.9-0.90.9-1.11.01.21.10.9-1.1-1.3-1.31.1-1.11.2-1.2
Intermittent access day 1 locomotion0.20.21.00.3-0.1-0.4-0.3-0.20.3-0.30.20.60.30.6-0.3-0.7-0.70.3-0.21.0-0.8
Intermittent access day 15 total locomotion0.00.00.20.2-0.4-0.0-0.10.00.10.1-0.10.2-0.10.20.1-0.3-0.3-0.10.10.1-0.2
Intermittent access total locomotion0.10.10.70.3-0.3-0.1-0.1-0.10.1-0.10.10.40.20.4-0.2-0.6-0.60.3-0.30.5-0.8
Intermittent access standard deviation0.20.20.60.6-0.30.40.50.3-0.50.3-0.2-0.4-0.2-0.40.20.40.4-0.20.2-0.80.4
Left kidney weight0.00.10.40.3-0.70.40.50.1-0.40.3-0.3-0.2-0.4-0.20.40.30.3-0.40.5-0.10.4
Right kidney weight0.61.62.21.2-1.51.31.41.1-1.31.3-1.3-1.2-1.4-1.11.41.21.2-1.41.5-1.01.3
Cocaine induced anxiety4.04.66.12.0-2.02.32.52.4-2.52.2-2.2-2.3-2.1-2.42.12.22.2-2.01.9-1.91.3
Post-drug Anxiety0.70.81.21.1-1.00.91.00.9-1.00.9-0.9-1.0-0.8-0.60.81.11.1-0.70.6-0.90.3
Baseline Anxiety3.94.25.5-1.82.0-2.2-2.4-2.32.4-2.22.22.02.12.3-2.1-1.9-1.92.0-1.91.5-1.1
Tail length1.54.67.1-2.12.0-2.4-2.4-2.52.3-2.12.12.61.92.3-1.8-2.5-2.71.6-1.32.5-0.8
Length with tail0.62.13.6-1.91.6-1.7-1.7-1.81.7-1.41.41.71.11.4-1.0-1.6-1.60.7-0.41.30.7
Length without tail1.12.35.20.7-1.01.41.41.4-1.31.4-1.5-1.3-1.6-1.61.61.41.6-1.81.8-1.62.3
Times rat made contact with spout1.72.03.7-1.01.2-1.2-1.2-1.21.2-1.41.41.31.51.2-1.5-1.5-1.51.6-1.71.4-1.9
Lifetime Intake0.30.30.50.00.4-0.5-0.4-0.40.4-0.50.50.70.60.3-0.6-0.7-0.70.6-0.60.7-0.7
Liver weight, left1.11.83.71.4-1.51.11.01.0-1.11.3-1.3-1.2-1.5-0.61.51.31.3-1.51.7-1.51.9
Liver weight, right0.20.30.90.5-0.30.40.30.3-0.30.6-0.6-0.4-0.7-0.00.70.40.5-0.70.9-0.51.0
Locomotor activity0.10.20.70.3-0.10.60.50.5-0.60.4-0.5-0.2-0.4-0.90.40.10.3-0.50.4-0.20.2
Locomotor testing distance0.50.81.4-0.80.9-0.8-0.9-0.80.8-0.80.81.10.90.9-0.9-1.2-1.10.9-0.91.0-1.0
Locomotor testing rearing0.91.43.2-0.80.9-1.0-1.1-0.91.1-1.11.11.21.21.5-1.2-1.2-1.21.3-1.41.2-1.8
Locomotion in novel chamber4.35.35.82.2-2.42.32.42.3-2.42.3-2.3-2.3-2.4-2.42.42.22.2-2.42.3-2.22.1
Locomotion in novel chamber post-restriction4.15.05.81.9-1.92.22.22.3-2.22.3-2.3-2.4-2.3-2.32.32.42.4-2.32.3-2.12.2
Fecal boli incidents, locomotor time 10.10.10.30.00.2-0.2-0.0-0.20.0-0.10.10.30.10.3-0.1-0.5-0.50.2-0.10.3-0.5
Change in fecal boli incidents, locomotor task0.20.20.7-0.30.2-0.3-0.2-0.30.2-0.40.40.50.40.1-0.5-0.6-0.60.5-0.50.5-0.8
Time >=10cm from walls, locomotor time 10.91.01.50.8-0.71.01.11.0-1.11.0-1.1-0.8-1.1-1.01.10.60.7-1.21.2-0.71.0
Bouts of movement, locomotor time 11.01.12.01.4-1.11.11.01.1-1.01.0-0.9-1.2-0.9-1.40.91.21.2-0.80.6-1.30.5
Total resting periods, locomotor time 11.71.82.71.6-1.41.41.31.4-1.31.3-1.3-1.5-1.2-1.71.21.41.4-1.11.0-1.60.8
Rest time, locomotor task time 10.20.21.50.5-0.1-0.0-0.0-0.10.0-0.10.10.20.20.1-0.3-0.5-0.60.4-0.41.1-1.2
Distance moved, locomotor task time 10.10.20.4-0.70.6-0.4-0.4-0.30.4-0.40.40.20.40.6-0.30.00.10.3-0.3-0.40.3
Vertical activity count, locomotor time 10.20.21.60.00.10.20.20.2-0.20.2-0.1-0.5-0.2-0.00.20.80.8-0.20.2-1.30.9
Time >=10cm from walls, locomotor time 21.31.42.0-1.41.4-1.2-1.0-1.31.0-1.31.31.31.20.8-1.2-1.3-1.21.1-1.11.0-0.7
Bouts of movement, locomotor time 23.03.35.31.9-1.71.91.81.9-1.81.7-1.7-2.2-1.5-2.11.52.32.2-1.41.2-2.31.2
Total resting periods, locomotor time 22.93.14.71.9-1.61.81.81.8-1.81.6-1.6-2.1-1.5-2.01.52.12.1-1.41.2-2.21.1
Rest time, locomotor task time 20.20.21.10.5-0.40.20.40.4-0.40.2-0.2-0.0-0.1-0.40.1-0.3-0.30.0-0.10.8-1.1
Distance moved, locomotor task time 20.20.20.5-0.70.6-0.4-0.5-0.50.5-0.40.40.20.40.6-0.30.0-0.00.2-0.2-0.30.6
Vertical activity count, locomotor time 20.10.11.2-0.2-0.00.20.0-0.1-0.0-0.00.1-0.40.1-0.2-0.10.60.60.1-0.1-1.10.6
Light reinforcement 14.58.210.22.9-3.23.13.13.1-3.23.0-3.0-2.8-2.9-2.82.92.62.7-2.82.7-2.82.0
Light reinforcement 21.01.42.81.2-1.71.21.31.3-1.31.2-1.2-1.1-1.2-1.11.21.00.9-1.21.1-1.00.8
Bone: marrow area0.20.43.4-1.00.5-0.5-0.7-0.60.7-0.30.20.20.00.40.10.10.0-0.40.6-0.21.8
Bone: maximum diameter0.20.30.90.3-0.90.40.40.5-0.40.6-0.6-0.4-0.6-0.40.60.40.4-0.70.7-0.60.8
Bone: maximum force0.81.36.70.3-0.70.50.50.6-0.50.9-0.9-1.0-1.1-0.61.21.31.2-1.51.6-1.32.6
Bone: maximum moment0.71.25.50.4-0.80.60.50.7-0.50.9-0.9-1.0-1.1-0.61.21.31.2-1.41.5-1.22.4
Mean time between licks in bursts3.34.76.51.9-2.52.22.22.2-2.22.2-2.3-2.1-2.2-2.32.22.12.0-2.22.1-1.91.7
Mean num. licks in bursts0.60.71.30.3-0.90.60.60.7-0.60.7-0.7-1.0-0.7-0.90.71.01.1-0.80.8-1.11.2
Cd content in liver0.20.21.20.0-0.4-0.0-0.00.00.00.2-0.3-0.3-0.40.10.40.40.8-0.50.6-0.51.1
Co content in liver2.02.43.2-1.71.1-1.4-1.4-1.41.4-1.51.51.61.61.2-1.6-1.7-1.61.6-1.61.8-1.8
Cu content in liver2.12.54.5-1.92.1-1.7-1.7-1.71.7-1.71.71.51.61.4-1.6-1.4-1.21.5-1.51.3-0.8
Fe content in liver2.83.44.5-2.11.7-2.0-2.0-1.92.0-1.91.92.11.81.9-1.8-2.1-1.71.7-1.61.8-1.1
K content in liver3.73.75.81.6-1.62.02.02.0-2.01.8-1.8-2.2-1.8-2.41.82.12.0-1.81.7-2.01.8
Mg content in liver1.41.42.91.0-0.91.21.31.3-1.31.1-1.1-1.5-1.1-1.71.11.41.2-1.10.9-1.10.8
Mn content in liver0.10.11.00.30.00.30.50.4-0.50.2-0.2-0.4-0.1-1.00.00.4-0.20.0-0.20.1-0.5
Na content in liver0.10.10.60.2-0.30.40.50.4-0.50.3-0.3-0.3-0.3-0.80.30.30.1-0.30.2-0.0-0.0
Rb content in liver3.03.75.71.6-1.32.02.02.0-2.02.0-2.0-2.1-2.0-2.42.02.02.0-2.01.9-1.71.8
Se content in liver0.30.30.60.5-0.60.50.50.5-0.50.5-0.5-0.6-0.5-0.60.50.70.6-0.50.4-0.80.6
Sr content in liver0.00.00.10.2-0.0-0.1-0.1-0.10.1-0.10.20.10.20.3-0.2-0.10.00.3-0.30.0-0.4
Zn content in liver0.30.41.00.8-1.00.50.50.5-0.50.6-0.6-0.6-0.5-0.10.50.60.8-0.50.5-0.90.4
Bone: minimum diameter0.61.13.90.5-0.80.70.70.8-0.71.0-1.0-0.9-1.1-0.61.21.11.0-1.31.5-1.12.0
Time in familiar zone, hab. session 10.20.21.0-0.10.1-0.2-0.3-0.30.3-0.30.30.30.40.5-0.4-0.4-0.50.5-0.60.7-1.0
Time in novel zone, hab. session 13.33.24.2-2.01.6-2.0-1.9-1.91.9-1.81.82.11.71.8-1.7-2.0-2.01.6-1.51.8-1.1
Total zone transitions, hab. session 10.60.81.70.7-1.00.70.70.7-0.70.9-0.9-0.8-1.0-0.61.00.80.8-1.11.2-0.91.3
Total locomotion distance, hab. session 11.01.44.80.6-1.30.70.80.9-0.81.1-1.1-0.8-1.3-0.61.40.91.0-1.51.7-1.22.2
Locomotion velocity, hab. session 12.13.06.31.3-1.81.41.41.6-1.41.7-1.7-1.5-1.8-1.21.91.61.7-2.02.1-1.92.5
Time in familiar zone, hab. session 20.20.20.7-0.20.0-0.2-0.3-0.40.3-0.40.40.40.4-0.0-0.4-0.5-0.60.5-0.50.8-0.8
Time in novel zone, hab. session 20.40.41.1-0.60.7-0.7-0.6-0.50.6-0.50.50.60.61.0-0.6-0.5-0.50.6-0.60.4-0.6
Total zone transitions, hab. session 20.00.00.1-0.1-0.2-0.1-0.1-0.10.1-0.20.2-0.00.20.1-0.20.10.10.2-0.30.0-0.2
Total locomotion distance, hab. session 20.10.10.8-0.3-0.6-0.1-0.10.20.10.2-0.2-0.1-0.30.20.30.30.3-0.40.5-0.30.9
Locomotion velocity, hab. session 20.20.31.40.1-0.80.20.20.4-0.20.4-0.5-0.4-0.5-0.20.60.50.5-0.70.7-0.61.2
Novel to familiar place preference ratio1.01.02.8-1.71.6-1.2-1.1-0.91.1-1.01.01.01.00.7-0.9-0.9-0.80.8-0.80.9-0.3
Novelty place preference1.31.32.8-1.71.6-1.2-1.2-1.01.2-1.11.11.11.10.8-1.1-1.0-1.01.0-1.01.1-0.7
Time in novel zone, NPP test1.61.73.3-1.81.7-1.4-1.3-1.21.3-1.31.31.31.31.0-1.2-1.2-1.11.1-1.21.2-0.8
Total zone transitions, NPP test0.20.30.50.7-0.60.50.50.6-0.50.5-0.5-0.6-0.5-0.30.50.60.6-0.40.4-0.50.2
Total locomotion distance, NPP test0.20.30.90.4-0.80.20.20.4-0.20.5-0.5-0.4-0.50.10.60.50.4-0.60.7-0.61.0
Locomotion velocity, NPP test0.50.71.20.8-1.10.60.60.8-0.60.8-0.8-0.8-0.9-0.30.90.80.7-0.91.0-0.91.1
Intraocular pressure0.20.30.9-0.5-0.3-0.4-0.4-0.30.4-0.50.40.60.50.7-0.5-0.6-0.50.6-0.60.6-0.9
Delta distance traveled before/after self-admin0.20.20.50.7-0.70.60.50.4-0.50.5-0.5-0.6-0.4-0.70.40.50.5-0.30.2-0.2-0.2
Delta ambulatory time before/after self-admin0.30.40.80.8-0.70.70.60.6-0.60.6-0.6-0.7-0.5-0.90.50.70.7-0.40.3-0.4-0.0
Parametrial fat weight0.00.00.10.2-0.40.10.0-0.0-0.1-0.00.0-0.10.0-0.0-0.10.10.10.1-0.10.0-0.4
Pavlov. Cond. lever latency2.12.63.71.8-1.71.81.81.8-1.81.9-1.9-1.3-1.9-1.51.81.01.1-1.81.8-0.80.7
Pavlov. Cond. magazine entry latency1.72.23.2-1.81.1-1.7-1.7-1.81.7-1.71.71.41.61.6-1.6-1.1-1.11.5-1.41.0-0.4
Pavlov. Cond. change in total contacts1.71.83.3-1.81.0-1.6-1.6-1.41.6-1.51.51.21.51.3-1.5-1.0-1.21.4-1.40.9-0.6
Pavlov. Cond. index score2.93.74.9-2.11.6-2.1-2.1-2.12.1-2.22.21.72.21.8-2.2-1.4-1.52.1-2.11.3-1.1
Pavlov. Cond. latency score2.63.34.5-2.11.7-2.0-2.0-2.02.0-2.12.11.62.11.7-2.0-1.3-1.42.0-2.01.1-0.9
Pavlov. Cond. lever contacts2.12.43.6-1.51.5-1.7-1.7-1.61.7-1.81.81.21.91.4-1.8-1.0-1.11.8-1.90.8-1.1
Pavlov. Cond. magazine entry number3.74.67.02.7-1.72.42.42.4-2.42.4-2.4-2.0-2.3-2.12.31.71.7-2.12.1-1.50.9
Pavlov. Cond. intertrial magazine entries0.00.10.10.20.10.10.20.3-0.20.3-0.3-0.3-0.3-0.20.30.30.3-0.30.3-0.10.2
Pavlov. Cond. lever-magazine prob. diff.2.22.73.8-1.91.3-1.8-1.8-1.81.8-1.91.91.41.91.5-1.9-1.2-1.31.8-1.81.0-0.9
Pavlov. Cond. response bias2.83.44.5-2.11.4-2.0-2.0-2.02.0-2.12.11.62.11.7-2.1-1.4-1.42.0-2.01.3-1.1
Pavlov. Cond. lever latency0.10.20.60.8-0.40.40.40.2-0.40.2-0.2-0.5-0.1-0.10.10.60.7-0.0-0.0-0.70.1
Pavlov. Cond. magazine entry latency0.10.10.5-0.50.2-0.5-0.5-0.40.6-0.30.20.40.20.7-0.2-0.4-0.20.10.00.50.0
Pavlov. Cond. change in total contacts0.71.01.8-1.30.8-1.2-1.2-1.01.2-0.80.81.20.71.1-0.7-1.3-1.30.6-0.51.3-0.5
Pavlov. Cond. index score0.20.30.7-0.80.5-0.6-0.7-0.50.6-0.30.30.70.20.7-0.2-0.7-0.80.10.00.80.0
Pavlov. Cond. latency score0.20.20.6-0.80.3-0.6-0.6-0.40.6-0.20.20.60.10.6-0.1-0.7-0.7-0.00.10.70.1
Pavlov. Cond. lever contacts0.30.41.0-1.00.5-0.6-0.6-0.50.6-0.40.40.80.30.4-0.3-0.8-1.00.2-0.11.0-0.3
Pavlov. Cond. magazine entry number0.60.71.50.9-0.71.01.00.9-1.00.7-0.7-0.9-0.6-1.20.60.90.9-0.60.4-0.90.3
Pavlov. Cond. intertrial magazine entries0.50.71.40.9-0.81.01.00.9-1.00.8-0.7-0.8-0.7-1.20.60.80.7-0.60.4-0.90.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.50.1-0.4-0.4-0.30.4-0.10.10.4-0.00.40.0-0.4-0.5-0.10.20.50.2
Pavlov. Cond. response bias0.20.20.9-0.90.5-0.5-0.5-0.40.5-0.20.20.60.10.3-0.1-0.6-0.8-0.10.20.80.2
Time in closed arm before self-admin2.32.64.4-2.11.4-1.8-1.7-1.81.7-1.51.51.91.41.7-1.4-1.8-1.81.3-1.11.5-0.9
Time in closed arm after self-admin0.10.10.4-0.3-0.2-0.0-0.1-0.00.10.1-0.1-0.1-0.20.00.20.20.2-0.20.3-0.40.6
Time in open arm before self-admin1.01.12.21.5-1.21.21.21.2-1.21.1-1.1-1.0-1.0-0.70.91.01.1-0.80.8-0.90.3
Time in open arm after self-admin1.51.62.3-1.21.5-1.3-1.3-1.41.3-1.31.31.41.21.2-1.2-1.4-1.41.1-1.01.4-0.7
Bone: periosteal estimation0.20.43.5-0.4-0.3-0.1-0.20.00.20.2-0.3-0.2-0.50.00.60.30.3-0.81.0-0.51.9
Bone: periosteal perimeter0.00.10.6-0.3-0.2-0.2-0.3-0.20.3-0.00.00.2-0.10.30.1-0.2-0.2-0.20.40.00.8
Bone: post-yield work0.20.32.10.0-0.20.00.1-0.0-0.10.2-0.2-0.4-0.3-0.10.40.70.6-0.50.7-0.71.5
Progressive ratio test 1 active lever presses0.10.10.30.5-0.3-0.00.0-0.0-0.00.1-0.10.3-0.10.30.1-0.3-0.3-0.00.10.4-0.2
Progressive ratio test 1 breakpoint0.10.10.50.7-0.40.20.10.1-0.10.2-0.20.1-0.20.00.2-0.1-0.1-0.20.30.2-0.1
Progressive ratio test 1 inactive lever presses0.30.30.60.7-0.60.60.70.5-0.70.5-0.5-0.4-0.5-0.80.50.40.4-0.50.5-0.30.3
Progressive ratio test 2 active lever presses0.40.40.7-0.40.8-0.8-0.6-0.60.6-0.70.70.70.70.5-0.7-0.7-0.70.6-0.70.6-0.4
Progressive ratio test 2 breakpoint0.50.50.7-0.30.8-0.8-0.7-0.70.7-0.80.80.70.80.7-0.8-0.7-0.70.8-0.80.7-0.7
Progressive ratio test 2 inactive lever presses0.20.20.50.10.7-0.4-0.2-0.50.2-0.50.50.50.50.3-0.5-0.5-0.50.5-0.50.6-0.4
Incentive Sensitization - Responses0.40.40.8-0.60.9-0.7-0.6-0.60.6-0.60.60.70.60.7-0.6-0.6-0.60.6-0.50.7-0.4
Incentive Sensitization - Breakpoint0.30.30.5-0.50.7-0.7-0.6-0.60.6-0.60.60.60.60.7-0.5-0.6-0.60.5-0.50.6-0.4
Sum of active levers in priming session hrs 5-61.01.01.6-1.31.2-1.1-1.1-1.11.1-1.01.01.11.00.6-0.9-1.0-1.00.8-0.80.9-0.3
Progressive ratio0.20.20.40.4-0.70.40.40.4-0.40.4-0.4-0.3-0.5-0.10.40.20.2-0.40.5-0.60.6
Food seeking constrained by brief footshock0.40.51.20.4-0.70.70.80.6-0.80.7-0.7-0.4-0.8-0.60.80.30.3-0.80.9-0.61.1
Seeking ratio, punishment vs. effort0.10.20.5-0.1-0.10.40.50.4-0.50.4-0.4-0.2-0.4-0.70.50.20.2-0.50.5-0.20.5
Retroperitoneal fat weight0.72.33.71.1-1.31.51.51.5-1.51.4-1.4-1.5-1.5-1.91.51.51.4-1.61.5-1.61.8
Reaction time number correct1.01.41.91.1-1.21.21.31.4-1.31.3-1.3-1.3-1.2-1.31.21.31.3-1.11.0-1.00.6
Reaction time mean minus median1.31.82.9-1.71.4-1.5-1.5-1.51.5-1.41.31.31.31.4-1.2-1.3-1.41.1-1.01.2-0.5
Reaction time mean minus median AUC1.11.52.0-1.41.3-1.3-1.4-1.41.4-1.31.31.11.21.2-1.2-1.1-1.31.1-1.01.2-0.6
Reaction time num false alarms3.95.39.02.7-3.02.42.32.5-2.22.4-2.4-2.4-2.4-2.12.32.42.1-2.22.1-1.91.3
Reaction time num false alarms AUC5.47.511.03.0-3.32.82.72.9-2.62.8-2.8-2.9-2.8-2.72.72.92.6-2.62.6-2.41.9
Reaction time trials correct on left1.01.41.91.1-1.21.21.31.4-1.31.3-1.3-1.3-1.2-1.31.21.31.3-1.11.0-1.00.6
Reaction time trials on left0.91.41.91.0-1.21.21.21.4-1.21.2-1.2-1.3-1.2-1.31.11.31.2-1.11.0-1.00.6
Reaction time mean3.34.78.7-2.92.7-2.4-2.4-2.42.4-2.32.32.12.22.0-2.1-1.9-1.91.9-1.81.5-0.4
Reaction time mean AUC3.14.27.7-2.82.7-2.2-2.3-2.32.3-2.22.22.02.11.7-2.0-1.8-1.81.8-1.71.4-0.5
Median of all reaction times3.34.68.5-2.92.7-2.3-2.3-2.42.4-2.32.32.12.21.9-2.1-1.9-1.81.9-1.81.4-0.5
Reaction time omissions1.82.43.2-1.71.2-1.6-1.7-1.51.7-1.61.61.41.61.8-1.6-1.5-1.51.6-1.61.3-1.4
Reaction time false alarm rate2.33.14.92.1-2.21.81.71.9-1.61.8-1.8-1.9-1.8-1.71.81.91.6-1.71.7-1.51.2
Reaction time premature initiation rate0.10.10.30.10.2-0.3-0.2-0.30.2-0.20.3-0.00.20.6-0.20.20.20.3-0.2-0.40.2
Reaction time premature initiations0.20.20.70.5-0.50.30.40.5-0.40.4-0.4-0.7-0.3-0.20.30.80.8-0.30.3-0.90.5
Std. dev. reaction times3.34.67.7-2.82.5-2.4-2.5-2.32.5-2.22.22.22.12.2-2.0-2.0-2.11.8-1.61.8-0.6
Reaction time trials completed0.91.41.91.0-1.21.21.21.4-1.21.2-1.2-1.3-1.2-1.31.11.31.2-1.11.0-1.00.6
Reaction time trials AUC0.81.21.61.0-1.11.11.21.3-1.11.1-1.1-1.2-1.1-1.21.01.11.2-1.00.9-0.90.5
Run reversals in cocaine runway, females2.22.23.81.0-1.11.51.51.6-1.51.5-1.6-1.3-1.6-1.91.61.21.2-1.71.6-1.31.5
Run reversals in cocaine runway, males1.61.52.10.8-1.41.31.31.1-1.31.2-1.2-1.3-1.2-1.31.21.21.2-1.21.2-1.41.1
Latency to leave start box in cocaine runway4.44.86.42.5-2.52.42.32.2-2.32.2-2.1-2.4-2.0-2.21.92.42.4-1.81.6-2.31.2
Latency to leave start box in cocaine runway, F1.71.83.21.8-1.81.51.51.4-1.51.3-1.3-1.6-1.2-1.41.11.51.5-0.90.8-1.30.3
Latency to leave start box in cocaine runway, M4.03.84.22.0-1.92.02.02.0-2.02.0-2.0-1.9-2.0-1.92.01.91.9-2.01.9-2.01.7
Std. dev. time between licks in bursts3.23.95.72.4-1.82.32.32.1-2.32.0-2.0-2.2-1.9-2.21.82.01.9-1.61.4-1.70.6
Total sessions with >9 infusions2.93.24.41.9-2.11.71.81.7-1.81.8-1.9-1.6-1.9-1.61.91.61.6-1.92.0-1.81.6
Short access day 1 total inactive lever presses0.60.61.31.1-1.10.90.80.6-0.80.9-0.9-0.7-0.9-0.30.90.60.6-0.81.0-0.30.4
Short access day 10 total inactive lever presses0.00.00.20.00.4-0.1-0.3-0.30.3-0.20.2-0.10.10.2-0.10.10.10.1-0.00.10.2
Short access day 1 total infusions0.80.91.31.0-0.70.91.10.9-1.11.0-1.0-0.7-1.0-1.11.00.70.7-1.11.1-0.51.0
Short access day 10 total infusions1.21.42.1-0.71.2-1.1-0.9-1.00.9-1.21.21.21.30.6-1.3-1.3-1.31.3-1.41.2-1.4
Short access total infusions0.10.10.40.6-0.20.30.40.3-0.40.3-0.3-0.3-0.3-0.50.30.20.2-0.30.3-0.20.2
Short access day 1 locomotion1.51.72.41.0-1.41.31.31.3-1.31.4-1.4-1.1-1.4-1.51.41.01.0-1.41.4-1.21.1
Short access day 10 total locomotion0.10.10.30.3-0.60.00.0-0.0-0.00.2-0.20.2-0.20.50.2-0.2-0.2-0.20.40.20.2
Short access total locomotion2.82.94.21.7-2.11.71.61.7-1.61.8-1.8-1.5-1.8-1.61.91.51.5-1.91.9-1.41.4
One hour access (0.3 mA shock)1.31.52.0-1.01.3-1.4-1.4-1.31.4-1.31.31.11.41.2-1.3-1.0-1.01.3-1.41.1-0.9
Compulsive drug intake0.10.10.4-0.10.6-0.1-0.2-0.20.2-0.20.2-0.30.20.1-0.20.40.40.3-0.3-0.10.1
One hour access (shock baseline)1.11.31.6-0.90.8-1.2-1.1-1.11.1-1.11.11.31.21.1-1.1-1.3-1.31.1-1.11.3-1.2
Social response proportion0.40.51.1-1.00.7-0.6-0.5-0.70.6-0.70.70.80.60.4-0.6-0.9-0.70.6-0.60.8-0.4
Social responses0.00.00.20.4-0.40.10.1-0.0-0.10.2-0.20.0-0.20.30.2-0.00.2-0.10.2-0.10.2
Social time1.41.82.2-1.41.2-1.5-1.4-1.41.4-1.41.41.21.41.3-1.4-1.3-1.21.4-1.41.1-1.1
Soleus weight2.16.07.42.3-2.72.32.32.3-2.32.4-2.4-2.6-2.5-2.42.52.62.5-2.52.5-2.42.5
Bone: stiffness1.11.77.00.4-1.00.80.70.8-0.71.1-1.1-1.2-1.3-0.81.41.51.4-1.61.8-1.42.7
Tibialis anterior weight4.214.417.33.7-3.64.04.04.0-4.03.8-3.8-4.1-3.7-4.23.74.04.1-3.63.3-3.72.7
Time to tail flick, vehicle, before self-admin0.00.10.30.2-0.3-0.1-0.1-0.10.0-0.10.1-0.10.10.5-0.20.10.10.3-0.2-0.2-0.5
Time to tail flick, vehicle, after self-admin0.40.40.8-0.90.7-0.7-0.8-0.60.8-0.70.70.60.70.6-0.7-0.5-0.50.7-0.60.6-0.5
Time to tail flick, test, before self-admin2.22.13.01.3-1.51.51.41.4-1.41.4-1.4-1.7-1.4-1.51.41.71.7-1.31.3-1.51.2
Time to tail flick, test, after self-admin2.72.83.71.6-1.71.81.81.7-1.81.6-1.6-1.9-1.6-1.71.61.91.9-1.51.4-1.61.1
Delta time to tail flick, vehicle, before/after SA0.20.10.4-0.70.7-0.4-0.5-0.30.5-0.40.40.40.30.0-0.3-0.4-0.40.2-0.20.40.2
Delta time to tail flick, test, before/after SA0.10.10.2-0.10.1-0.2-0.1-0.20.1-0.20.20.20.20.4-0.2-0.2-0.20.3-0.20.2-0.4
Tibia length0.20.64.3-1.40.8-0.7-0.7-0.80.7-0.30.30.7-0.00.50.2-0.5-0.1-0.50.8-0.12.1
Ambulatory time before self-admin0.50.51.2-1.10.9-0.9-0.8-0.70.8-0.60.50.90.40.8-0.3-0.8-0.80.10.00.60.6
Ambulatory time after self-admin0.20.20.40.3-0.30.40.40.4-0.40.5-0.5-0.3-0.5-0.60.60.20.2-0.60.6-0.00.6
Bone: tissue strength0.10.10.80.4-0.90.20.30.2-0.30.3-0.3-0.3-0.30.10.30.40.4-0.30.4-0.40.4
Total heroin consumption0.70.81.1-1.10.8-0.9-0.9-1.00.9-1.01.00.81.00.6-1.0-0.8-0.91.0-1.00.7-0.8
Bone: trabecular number0.81.21.6-1.21.2-1.2-1.2-1.11.2-1.11.11.31.01.2-1.0-1.3-1.30.9-0.81.3-0.6
Bone: trabecular spacing1.11.41.91.0-1.21.11.21.2-1.21.1-1.1-1.2-1.1-1.31.11.31.3-1.21.1-1.41.2
Bone: trabecular thickness5.66.78.8-2.72.3-2.8-2.9-2.72.9-2.62.62.62.53.0-2.5-2.5-2.52.5-2.32.6-1.9
Bone: trabecular tissue density0.00.00.2-0.30.10.1-0.00.10.00.1-0.20.0-0.2-0.20.2-0.00.1-0.30.40.10.4
Water consumed over 24 hours0.00.10.30.5-0.50.20.20.2-0.20.1-0.1-0.2-0.10.20.00.00.00.1-0.10.1-0.6
Number of responses in last shaping day0.20.20.70.0-0.20.50.40.5-0.40.4-0.4-0.5-0.4-0.80.40.40.4-0.40.3-0.40.2