Hub : Genes

Wdr75

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Wdr75 0.05 0.04 7.3e-03 0.03 0.02 0.02 0.02 1.3e-02 3.1e-02 2.5e-02 3.7e-02
2 BLA gene expression Wdr75 0.34 0.16 0.0e+00 0.27 0.23 0.24 0.26 1.9e-14 2.3e-12 4.7e-13 5.5e-14
3 pVTA mRNA stability Wdr75 0.07 0.06 2.7e-05 0.05 0.06 0.04 0.05 6.9e-05 2.8e-05 2.6e-04 3.8e-05
4 IC gene expression Wdr75 0.41 0.14 0.0e+00 0.29 0.32 0.32 0.32 7.9e-13 2.9e-14 3.1e-14 8.7e-14
5 Adipose mRNA stability Wdr75 0.28 0.13 0.0e+00 0.12 0.12 0.12 0.13 1.4e-13 1.4e-13 5.6e-13 5.1e-14
6 NAcc gene expression Wdr75 0.15 0.08 0.0e+00 0.14 0.15 0.15 0.15 8.0e-21 2.0e-22 1.5e-21 1.9e-21
7 Adipose gene expression Wdr75 0.19 0.1 0.0e+00 0.11 0.12 0.11 0.11 3.8e-12 1.1e-12 2.5e-12 3.6e-12
8 PL mRNA stability Wdr75 0.07 0.04 4.3e-09 0.05 0.07 0.06 0.06 1.7e-06 1.9e-08 2.7e-07 2.8e-07
9 NAcc mRNA stability Wdr75 0.07 0.04 1.2e-11 0.07 0.06 0.07 0.07 1.9e-10 4.2e-10 1.9e-10 1.7e-10
10 OFC gene expression Wdr75 0.57 0.16 4.3e-10 0.26 0.27 0.28 0.27 5.8e-07 5.0e-07 2.7e-07 3.1e-07
11 RMTg mRNA stability Wdr75 0.2 0.12 1.3e-04 0.13 0.13 0.07 0.11 3.1e-04 2.2e-04 6.3e-03 7.8e-04
12 PL gene expression Wdr75 0.63 0.12 0.0e+00 0.29 0.31 0.29 0.3 4.7e-32 3.0e-34 1.9e-31 3.5e-33
13 Brain gene expression Wdr75 0.22 0.11 0.0e+00 0.25 0.27 0.27 0.27 3.0e-23 2.0e-25 6.8e-25 4.6e-25
14 Brain mRNA stability Wdr75 0.19 0.1 0.0e+00 0.21 0.23 0.26 0.23 4.1e-19 2.3e-21 2.7e-24 4.1e-21
15 Liver mRNA stability Wdr75 0.06 0.04 3.5e-06 0.02 0.03 0.01 0.02 1.2e-03 2.4e-04 6.9e-03 1.2e-03
16 IL gene expression Wdr75 0.46 0.19 2.8e-06 0.14 0.13 0.1 0.14 2.7e-04 4.7e-04 1.7e-03 4.0e-04
17 Liver gene expression Wdr75 0.06 0.04 1.4e-06 0.01 0.02 0.01 0.01 9.7e-03 3.9e-03 1.3e-02 5.8e-02
18 RMTg gene expression Wdr75 0.19 0.12 5.9e-04 0.04 0.1 0.1 0.09 2.5e-02 1.4e-03 1.4e-03 2.6e-03
19 pVTA gene expression Wdr75 0.14 0.08 9.3e-07 0.05 0.05 0.06 0.06 4.9e-05 8.1e-05 1.4e-05 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density2.24.15.02.2-1.9-2.12.1-2.12.12.1-2.0-2.2-2.2-2.02.12.02.2-1.9-2.11.81.8-1.1
Area under the delay curve0.00.00.20.10.0-0.10.1-0.10.10.1-0.10.10.4-0.10.00.10.0-0.10.20.10.10.1
BMI with tail1.34.57.1-2.42.62.7-2.62.5-2.3-2.22.22.12.42.0-2.0-1.9-2.01.72.0-1.5-1.5-0.5
BMI without tail0.10.53.40.1-0.1-0.10.2-0.20.40.4-0.5-0.9-0.4-0.50.60.60.4-0.7-0.70.90.9-1.9
Body weight0.00.10.40.5-0.1-0.20.3-0.40.30.2-0.3-0.7-0.5-0.20.60.20.6-0.2-0.50.20.20.1
Weight adjusted by age0.51.54.4-1.10.70.7-0.90.9-1.0-1.11.11.30.91.1-1.6-1.2-1.31.31.1-1.4-1.52.1
Bone surface0.00.10.70.2-0.0-0.10.0-0.0-0.0-0.10.1-0.2-0.10.2-0.0-0.20.10.2-0.0-0.3-0.30.8
Bone volume0.61.11.91.4-1.2-1.21.2-1.21.11.1-1.0-1.1-1.2-1.01.00.91.2-0.8-1.10.70.70.1
Breakpoint value in progressive ratio session0.91.72.41.3-1.5-1.41.4-1.31.31.4-1.4-1.2-1.3-1.41.01.31.4-1.3-1.41.31.3-0.9
Number of licking bursts0.72.03.41.4-1.0-1.11.2-1.31.31.4-1.4-1.3-1.3-1.41.71.51.3-1.5-1.41.61.7-1.8
Context. condit. distance diff. score0.70.95.10.4-0.7-0.60.6-0.50.70.8-0.9-0.8-0.4-1.00.41.00.7-1.1-0.61.31.3-2.3
Locomotion velocity, session 10.10.10.20.3-0.3-0.20.2-0.30.30.3-0.3-0.3-0.2-0.30.40.30.3-0.3-0.10.40.3-0.4
Locomotion distance, session 10.50.60.9-0.70.90.8-0.90.8-0.8-0.80.80.90.70.8-0.9-0.8-0.70.80.6-0.8-0.80.5
Locomotion velocity, session 21.61.92.7-1.41.61.6-1.61.4-1.4-1.51.51.51.01.5-1.1-1.4-1.21.41.0-1.4-1.41.0
Locomotion distance, session 21.52.13.0-1.31.71.5-1.51.4-1.5-1.51.51.21.31.5-1.4-1.5-1.41.51.3-1.5-1.51.2
Locomotion velocity, session 30.10.10.2-0.20.40.3-0.30.3-0.3-0.20.20.00.30.2-0.4-0.2-0.20.20.2-0.1-0.2-0.2
Locomotion distance, session 30.10.10.80.2-0.0-0.10.1-0.10.20.2-0.2-0.6-0.1-0.3-0.00.30.2-0.3-0.30.40.4-0.9
Stereotopy head waving bouts, day 30.40.50.9-0.80.70.8-0.80.8-0.7-0.70.70.80.90.7-0.6-0.7-0.70.70.9-0.6-0.60.3
Stereotopy head waving duration, day 30.00.00.1-0.0-0.10.0-0.0-0.00.00.1-0.00.00.1-0.00.20.00.1-0.10.10.10.1-0.1
Locomotion velocity, session 72.12.33.4-1.51.51.4-1.41.4-1.4-1.51.51.81.41.5-1.4-1.6-1.51.61.5-1.6-1.61.8
Locomotion distance, session 71.21.52.1-1.31.31.1-1.21.1-1.2-1.21.21.21.01.3-1.1-1.3-1.31.31.1-1.3-1.31.4
Stereotopy head waving bouts, day 70.30.40.70.8-0.6-0.70.7-0.60.60.7-0.7-0.5-0.6-0.70.40.70.6-0.6-0.60.60.6-0.6
Stereotopy head waving duration, day 70.40.51.01.0-0.7-0.80.8-0.80.80.8-0.8-0.7-0.8-0.80.60.70.8-0.7-0.70.70.7-0.3
Locomotion velocity, session 80.00.00.4-0.10.10.0-0.00.10.00.1-0.10.1-0.0-0.1-0.10.1-0.0-0.2-0.00.30.2-0.6
Locomotion distance, session 80.20.30.7-0.70.70.7-0.70.6-0.6-0.50.50.30.70.4-0.7-0.3-0.60.30.5-0.1-0.1-0.8
Degree of sensitization distance1.01.13.4-1.00.80.8-0.80.7-0.9-0.91.01.20.81.1-0.6-1.1-1.01.11.0-1.2-1.21.8
Degree of sensitization stereotypy0.50.50.80.9-0.6-0.80.7-0.70.70.7-0.7-0.7-0.7-0.80.40.80.7-0.7-0.70.70.7-0.7
Conditioned locomotion0.00.00.30.2-0.1-0.10.1-0.10.10.1-0.1-0.60.1-0.00.10.10.0-0.00.10.00.0-0.0
Cocaine response after cond. corrected0.91.42.3-1.01.41.1-1.11.0-1.2-1.21.21.00.81.3-1.0-1.3-1.11.30.9-1.4-1.41.5
Cocaine response after cond. not corrected1.11.54.8-1.01.20.9-1.00.9-1.1-1.21.20.90.81.3-1.0-1.3-1.11.41.0-1.6-1.62.2
Cocaine response before conditioning0.10.21.2-0.3-0.2-0.0-0.10.1-0.2-0.20.30.20.30.3-0.5-0.3-0.30.40.4-0.5-0.51.1
Saline control response0.20.20.60.5-0.7-0.40.4-0.50.40.4-0.5-0.3-0.4-0.50.10.50.4-0.5-0.50.60.5-0.8
Bone: connectivity density0.20.30.70.5-0.4-0.50.5-0.50.50.5-0.5-0.8-0.7-0.50.40.50.7-0.4-0.70.40.4-0.3
Bone: cortical apparent density3.75.98.0-2.62.82.8-2.72.7-2.6-2.62.52.32.52.4-2.3-2.4-2.42.32.3-2.1-2.10.9
Bone: cortical area0.71.21.6-0.91.01.1-1.11.1-1.1-1.11.21.01.01.2-1.1-1.2-0.91.20.9-1.3-1.31.3
Bone: cortical porosity1.11.22.01.3-1.4-1.31.2-1.11.11.2-1.2-0.8-0.9-1.20.71.11.0-1.1-0.71.11.0-0.8
Bone: cortical porosity0.80.91.91.2-1.4-1.21.2-1.11.01.1-1.0-0.8-0.7-1.00.61.00.9-0.9-0.50.80.8-0.3
Bone: cortical thickness0.91.62.2-1.31.41.5-1.51.5-1.3-1.31.31.01.41.3-1.3-1.2-1.11.21.1-1.1-1.10.3
Bone: cortical thickness0.30.40.6-0.40.60.6-0.60.6-0.6-0.70.70.50.60.7-0.7-0.7-0.60.70.6-0.7-0.80.8
Bone: cortical tissue density3.65.77.8-2.62.82.7-2.72.6-2.5-2.52.52.32.42.4-2.3-2.4-2.42.32.3-2.1-2.10.9
Condit. Reinf. active minus inactive responses3.53.95.62.4-2.3-2.22.2-2.22.12.0-2.0-2.1-2.1-1.91.91.92.0-1.8-1.91.71.6-0.6
Condit. Reinf. active-inactive response ratio2.42.53.61.9-1.8-1.81.7-1.71.61.6-1.6-1.9-1.8-1.51.51.51.6-1.4-1.61.31.3-0.6
Condit. Reinf. active responses1.52.03.21.8-1.6-1.71.6-1.71.51.5-1.4-1.4-1.5-1.31.51.31.4-1.2-1.21.01.00.1
Condit. Reinf. inactive responses0.20.20.7-0.30.40.3-0.30.2-0.3-0.40.40.70.40.4-0.1-0.4-0.40.40.6-0.5-0.50.8
Incentive salience index mean3.13.95.52.4-2.2-2.22.1-2.12.12.0-2.0-2.0-2.1-2.01.82.02.0-1.9-1.91.81.7-0.9
Condit. Reinf. lever presses1.42.22.81.7-1.5-1.61.5-1.41.51.5-1.5-1.4-1.3-1.61.21.51.4-1.5-1.21.51.5-1.3
Condit. Reinf. active minus inactive responses0.60.91.91.0-1.4-1.31.2-1.11.11.0-1.0-0.6-1.3-0.90.60.91.0-0.7-1.20.60.50.5
Condit. Reinf. active-inactive response ratio1.11.72.81.3-1.7-1.61.5-1.41.41.4-1.4-0.9-1.3-1.41.01.31.3-1.2-1.31.11.1-0.3
Condit. Reinf. active responses0.10.10.60.2-0.4-0.30.2-0.20.10.1-0.1-0.2-0.4-0.0-0.2-0.00.10.1-0.3-0.2-0.20.7
Condit. Reinf. inactive responses0.60.91.4-0.80.80.9-1.00.9-1.0-1.11.10.80.71.1-1.0-1.1-0.91.10.8-1.1-1.21.2
Condit. Reinf. lever presses0.00.00.20.2-0.2-0.10.1-0.20.10.1-0.1-0.2-0.4-0.10.10.10.2-0.0-0.4-0.0-0.00.1
Condit. Reinf. lever reinforcers received0.10.10.9-0.0-0.2-0.10.0-0.0-0.1-0.10.20.0-0.20.2-0.3-0.2-0.10.3-0.1-0.4-0.51.0
Conditioned reinforcement - actives0.00.10.2-0.30.30.3-0.40.3-0.3-0.30.30.20.40.3-0.2-0.3-0.30.20.3-0.2-0.20.1
Conditioned reinforcement - inactives0.10.41.3-0.60.50.4-0.40.6-0.5-0.50.60.60.50.5-1.1-0.6-0.70.60.4-0.6-0.70.6
Conditioned locomotion3.34.95.5-2.32.32.3-2.32.3-2.3-2.32.32.02.02.3-2.3-2.3-2.12.32.1-2.3-2.31.5
Patch foraging indifference point 0 sec0.71.93.5-1.51.91.8-1.71.5-1.5-1.51.51.61.11.4-1.1-1.3-1.11.20.9-1.1-1.10.2
Patch foraging indifference point AUC0.30.71.2-0.80.90.9-0.80.7-0.9-0.90.90.50.71.0-0.5-1.0-0.71.00.8-1.0-1.01.1
Delay disc. indifference point, 0s delay0.10.10.3-0.10.30.1-0.20.2-0.2-0.20.20.50.30.1-0.4-0.2-0.10.20.3-0.2-0.20.2
Delay disc. indifference point, 16s delay0.60.81.31.1-1.0-1.01.0-1.21.01.0-1.0-0.8-0.5-0.91.00.90.8-0.9-0.70.90.9-0.2
Delay disc. indifference point, 2s delay0.10.10.2-0.30.50.2-0.20.3-0.2-0.20.20.30.30.2-0.2-0.2-0.20.20.3-0.2-0.20.3
Delay disc. indifference point, 24s delay0.30.40.80.5-0.5-0.60.6-0.60.60.7-0.7-0.9-0.2-0.70.70.70.7-0.8-0.50.80.8-0.9
Delay disc. indifference point, 4s delay0.40.41.0-0.60.80.6-0.60.7-0.6-0.50.51.01.00.5-0.6-0.5-0.70.51.0-0.5-0.50.3
Delay disc. indifference point, 8s delay0.10.10.30.6-0.3-0.50.4-0.40.40.4-0.4-0.2-0.1-0.40.30.30.4-0.3-0.30.30.20.2
Indifference point function ln k0.10.31.70.5-0.2-0.40.3-0.30.50.5-0.5-0.0-0.3-0.60.30.60.4-0.7-0.50.80.8-1.3
Indifference point function log k0.10.31.70.5-0.2-0.40.3-0.30.50.5-0.5-0.0-0.3-0.60.30.60.4-0.7-0.50.80.8-1.3
Patch foraging total patch changes 0 sec0.72.13.7-1.61.91.8-1.71.6-1.5-1.61.51.81.21.5-1.2-1.4-1.21.30.9-1.2-1.20.2
Patch foraging total patch changes 12 sec0.40.60.9-0.81.00.9-0.90.7-0.8-0.90.80.60.50.9-0.4-0.8-0.60.80.5-0.8-0.80.7
Patch foraging total patch changes 18 sec0.40.91.5-1.01.21.2-1.20.8-1.1-1.11.10.90.91.0-0.7-1.0-0.90.90.9-0.9-0.80.3
Patch foraging total patch changes 24 sec0.31.11.6-1.21.01.1-1.11.0-1.1-1.11.11.21.11.0-1.1-1.0-1.01.01.1-1.0-1.00.5
Patch foraging total patch changes 6 sec1.42.43.9-1.82.01.9-1.81.6-1.7-1.71.61.71.51.6-1.2-1.6-1.41.41.4-1.3-1.30.5
Patch foraging time to switch 0 sec0.20.81.50.9-1.2-1.11.0-1.00.91.0-0.9-0.8-0.7-1.00.60.90.7-0.9-0.60.90.8-0.5
Patch foraging water rate 0 sec0.10.51.3-0.71.10.9-0.80.8-0.7-0.80.70.50.30.8-0.3-0.7-0.40.70.2-0.6-0.60.3
Patch foraging water rate 12 sec0.00.10.60.20.0-0.00.1-0.00.10.2-0.2-0.2-0.2-0.20.10.30.2-0.3-0.30.40.4-0.8
Patch foraging water rate 18 sec0.30.71.50.7-0.7-0.80.8-0.70.80.8-0.9-0.9-0.7-0.90.60.90.8-0.9-0.81.01.0-1.2
Patch foraging water rate 24 sec0.00.00.10.10.00.00.0-0.00.0-0.00.0-0.0-0.00.00.2-0.00.10.0-0.1-0.1-0.00.2
Patch foraging water rate 6 sec0.10.11.1-0.10.10.2-0.20.3-0.1-0.10.00.10.1-0.1-0.30.1-0.0-0.2-0.10.30.3-1.0
Seeking ratio, delayed vs. immediate footshock0.50.71.71.0-1.2-0.90.8-0.90.80.7-0.7-0.8-1.3-0.60.70.61.0-0.5-1.10.40.40.3
Distance traveled before self-admin0.61.21.91.3-1.4-1.41.4-1.41.21.1-1.1-0.9-1.4-1.01.11.01.1-0.9-1.20.70.70.4
Distance traveled after self-admin0.30.50.80.8-0.9-0.80.7-0.90.70.7-0.7-0.8-0.9-0.60.60.60.5-0.5-0.60.40.40.3
Extensor digitorum longus weight9.738.644.9-6.45.96.3-6.36.4-6.4-6.46.36.46.56.2-6.7-6.3-6.36.26.3-6.1-6.14.3
Bone: elastic displacement2.22.83.61.4-1.4-1.51.6-1.51.71.7-1.7-1.8-1.5-1.71.71.71.6-1.8-1.71.81.8-1.9
Bone: elastic work0.70.91.41.1-1.1-1.21.1-1.11.01.0-1.0-1.2-0.8-1.00.90.90.9-0.9-0.80.80.8-0.2
Bone: endosteal estimation0.10.43.20.7-0.8-0.70.6-0.70.40.3-0.30.2-0.3-0.20.30.10.30.1-0.0-0.3-0.31.8
Bone: endosteal perimeter0.10.20.90.5-0.6-0.60.5-0.50.40.3-0.3-0.3-0.6-0.20.50.20.4-0.1-0.5-0.1-0.11.0
Epididymis fat weight0.20.94.5-0.30.60.5-0.60.5-0.8-0.80.90.70.81.0-0.9-1.0-0.71.10.9-1.3-1.32.1
Delta time in closed arm before/after self-admin0.50.50.8-0.70.90.7-0.70.7-0.7-0.70.70.80.80.7-0.7-0.7-0.70.70.7-0.6-0.60.4
Delta time in open arm before/after self-admin1.11.32.41.1-1.5-1.41.3-1.21.21.2-1.2-1.4-1.3-1.10.81.11.0-1.0-1.10.90.8-0.1
Diff in mean of infusions in LGA sessions0.50.91.31.0-1.1-1.01.1-1.00.91.0-1.0-1.0-0.8-0.90.70.91.0-0.9-0.70.80.8-0.7
Delay discount exponential model param0.00.00.2-0.1-0.00.1-0.10.1-0.1-0.10.1-0.1-0.40.1-0.0-0.1-0.00.1-0.2-0.1-0.1-0.0
Extinction: sum of active levers before priming0.91.31.71.2-1.3-1.21.1-1.31.21.2-1.2-1.0-1.3-1.21.11.21.2-1.1-1.31.11.1-0.6
Active lever presses in extinction session 60.60.61.00.8-1.0-1.00.8-0.70.80.9-0.8-0.5-0.9-0.90.30.80.6-0.8-0.90.70.7-0.2
Bone: final force0.60.93.5-0.70.60.6-0.70.6-0.8-0.80.91.10.91.0-0.8-1.0-0.81.10.9-1.2-1.21.9
Bone: final moment0.50.92.7-0.70.60.7-0.70.7-0.8-0.90.91.00.90.9-0.7-1.0-0.81.00.9-1.1-1.11.6
Food consumed during 24 hour testing period0.10.21.2-0.30.30.3-0.30.3-0.4-0.40.40.00.20.5-0.3-0.5-0.40.60.4-0.7-0.61.1
Glucose1.11.73.91.0-1.0-0.91.0-0.91.11.1-1.2-1.5-1.5-1.21.21.31.3-1.3-1.71.41.5-2.0
Heart weight0.00.10.30.3-0.6-0.30.3-0.20.20.2-0.2-0.3-0.2-0.10.20.10.2-0.1-0.20.10.10.3
Delay discount hyperbolic model param0.00.00.3-0.0-0.10.1-0.0-0.0-0.0-0.10.1-0.2-0.50.10.0-0.10.10.1-0.3-0.1-0.1-0.0
Intermittent access intake day 1-15 change0.00.00.3-0.20.20.2-0.10.0-0.1-0.00.0-0.10.60.00.2-0.0-0.1-0.00.40.10.1-0.3
Intermittent access intake escalation0.00.10.4-0.20.30.2-0.10.0-0.0-0.0-0.0-0.10.6-0.00.40.0-0.1-0.10.30.20.2-0.7
Intermittent access intake escalation 20.20.30.60.3-0.4-0.50.5-0.50.50.6-0.6-0.60.2-0.60.70.60.3-0.7-0.00.70.8-0.7
Intermitt. access day 1 inactive lever presses0.00.31.0-0.60.50.7-0.60.6-0.5-0.40.30.31.00.2-0.3-0.2-0.60.10.70.10.1-1.0
Intermitt. access day 15 inactive lever presses0.10.30.9-0.60.30.5-0.50.7-0.6-0.50.50.70.60.4-0.9-0.4-0.60.40.5-0.3-0.4-0.1
Intermitt. access escalation Index0.20.51.20.7-0.5-0.50.6-0.60.60.6-0.7-0.7-0.8-0.60.90.70.8-0.8-0.70.80.8-1.1
Intermittent access day 1 total infusions0.41.22.11.1-0.7-1.01.0-1.11.11.0-1.0-0.9-1.4-1.11.21.11.3-1.1-1.51.11.1-1.2
Intermittent access day 15 total infusions0.20.42.00.40.0-0.20.3-0.50.50.5-0.5-0.4-0.3-0.50.90.60.6-0.7-0.50.80.9-1.4
Intermittent access terminal intake (last 3 days)0.10.11.20.00.30.1-0.0-0.10.20.2-0.2-0.00.1-0.30.50.30.2-0.4-0.20.60.6-1.1
Intermittent access total infusions0.30.41.20.5-0.1-0.40.5-0.50.60.6-0.6-0.4-0.6-0.60.80.60.7-0.7-0.80.80.8-1.1
Intermittent access day 1 locomotion0.10.10.40.30.2-0.00.2-0.30.10.1-0.1-0.4-0.6-0.10.40.10.5-0.1-0.50.10.2-0.7
Intermittent access day 15 total locomotion0.20.71.9-0.91.41.0-0.90.8-0.9-0.90.90.60.70.9-0.4-0.9-0.60.90.6-0.9-0.80.5
Intermittent access total locomotion0.10.20.8-0.40.90.6-0.40.4-0.4-0.40.40.20.20.4-0.1-0.3-0.10.30.0-0.2-0.2-0.8
Intermittent access standard deviation0.10.30.7-0.60.70.6-0.60.7-0.6-0.50.50.50.80.5-0.7-0.5-0.50.50.6-0.5-0.50.2
Left kidney weight0.10.61.40.7-0.9-0.70.7-0.50.70.7-0.7-1.0-1.1-0.60.70.70.9-0.6-1.20.60.7-0.5
Right kidney weight0.10.60.9-0.70.60.8-0.80.9-0.8-0.80.80.40.60.9-0.7-0.8-0.50.80.4-0.9-0.80.8
Cocaine induced anxiety0.61.82.8-1.51.31.4-1.41.5-1.4-1.41.31.21.41.3-1.7-1.3-1.51.21.4-1.1-1.20.3
Post-drug Anxiety1.51.72.4-1.51.51.4-1.31.4-1.3-1.31.31.11.41.3-1.1-1.3-1.31.31.4-1.2-1.20.6
Baseline Anxiety0.30.61.20.8-0.8-0.90.8-0.90.80.8-0.8-0.7-0.7-0.71.10.70.9-0.7-0.70.60.60.2
Tail length2.111.216.43.6-3.3-3.63.7-3.63.43.3-3.3-4.1-4.0-3.13.63.13.5-2.9-3.82.72.7-0.8
Length with tail1.67.211.03.3-2.8-3.13.1-3.02.82.6-2.6-3.1-3.3-2.33.02.32.9-2.0-2.91.71.70.8
Length without tail0.10.45.20.9-0.3-0.40.4-0.40.20.00.0-0.1-0.30.20.3-0.30.40.4-0.0-0.7-0.72.3
Times rat made contact with spout1.72.03.91.3-1.3-1.21.2-1.21.31.4-1.4-1.5-1.2-1.41.21.51.3-1.5-1.31.61.6-2.0
Lifetime Intake0.00.10.4-0.10.50.2-0.10.1-0.0-0.00.00.30.1-0.00.20.00.1-0.1-0.20.20.2-0.6
Liver weight, left0.10.11.30.2-0.1-0.20.2-0.30.20.1-0.1-0.2-0.30.00.6-0.00.20.1-0.2-0.2-0.21.1
Liver weight, right0.20.30.90.7-0.5-0.50.5-0.60.50.4-0.4-1.0-0.9-0.30.80.40.7-0.3-0.80.20.20.4
Locomotor activity0.10.20.8-0.40.30.4-0.40.6-0.4-0.40.40.30.40.4-0.9-0.4-0.50.40.3-0.4-0.50.2
Locomotor testing distance0.30.71.50.9-0.6-0.70.7-0.70.80.8-0.8-1.2-0.8-0.80.80.80.9-0.8-0.90.80.8-0.9
Locomotor testing rearing0.31.32.61.0-0.8-0.80.9-0.91.01.0-1.0-1.2-1.1-1.11.31.11.1-1.2-1.31.31.3-1.6
Locomotion in novel chamber3.64.95.5-2.32.22.2-2.22.2-2.2-2.32.32.21.92.3-2.1-2.3-2.22.31.9-2.3-2.32.1
Locomotion in novel chamber post-restriction2.06.17.1-2.52.32.4-2.42.3-2.5-2.52.52.62.62.5-2.5-2.5-2.62.52.7-2.5-2.52.0
Fecal boli incidents, locomotor time 10.10.30.70.4-0.2-0.40.5-0.40.50.4-0.5-0.7-0.8-0.40.60.50.5-0.5-0.80.50.5-0.6
Change in fecal boli incidents, locomotor task0.00.00.30.0-0.00.00.00.10.00.0-0.00.1-0.2-0.1-0.30.10.2-0.1-0.30.10.1-0.5
Time >=10cm from walls, locomotor time 10.91.11.7-0.91.01.0-0.91.0-1.1-1.11.11.20.81.1-1.1-1.1-0.91.20.8-1.2-1.21.3
Bouts of movement, locomotor time 10.81.11.8-1.21.11.1-1.11.1-1.1-1.01.01.11.40.9-1.4-0.9-1.10.91.3-0.8-0.80.1
Total resting periods, locomotor time 11.61.92.7-1.61.41.4-1.51.4-1.4-1.31.31.41.61.3-1.6-1.3-1.41.21.5-1.1-1.10.5
Rest time, locomotor task time 10.10.20.70.2-0.2-0.00.1-0.10.20.2-0.3-0.5-0.7-0.30.30.30.4-0.4-0.60.40.5-0.8
Distance moved, locomotor task time 10.10.20.40.5-0.5-0.60.6-0.50.60.6-0.5-0.20.1-0.50.60.50.5-0.5-0.10.50.5-0.3
Vertical activity count, locomotor time 10.00.10.7-0.2-0.00.0-0.00.2-0.1-0.10.10.40.80.1-0.1-0.1-0.20.10.6-0.1-0.10.2
Time >=10cm from walls, locomotor time 20.51.32.01.3-1.4-1.31.3-1.11.21.2-1.2-1.2-1.1-1.20.81.21.1-1.1-1.11.11.0-0.6
Bouts of movement, locomotor time 21.13.76.6-2.11.91.9-2.01.9-1.9-1.81.82.22.61.7-2.4-1.7-2.21.62.4-1.5-1.60.4
Total resting periods, locomotor time 20.93.55.9-2.11.81.9-1.91.8-1.9-1.81.82.22.41.6-2.3-1.7-2.21.62.3-1.4-1.50.3
Rest time, locomotor task time 20.10.10.4-0.00.30.5-0.40.5-0.3-0.30.20.4-0.30.2-0.3-0.1-0.10.1-0.30.00.0-0.6
Distance moved, locomotor task time 20.10.20.30.3-0.5-0.60.5-0.50.50.5-0.4-0.40.0-0.40.60.40.5-0.3-0.10.30.30.2
Vertical activity count, locomotor time 20.00.10.7-0.3-0.2-0.0-0.00.1-0.00.0-0.0-0.00.8-0.1-0.20.0-0.2-0.00.70.10.0-0.1
Light reinforcement 11.98.610.6-3.33.03.2-3.23.1-3.1-3.13.12.52.93.0-3.0-3.0-3.02.92.8-2.8-2.81.5
Light reinforcement 20.61.42.0-1.41.31.3-1.21.3-1.3-1.21.20.71.01.2-1.3-1.2-1.21.21.0-1.1-1.10.6
Bone: marrow area0.10.33.20.6-0.7-0.60.6-0.60.30.3-0.20.2-0.2-0.10.30.00.20.10.0-0.4-0.41.8
Bone: maximum diameter0.10.20.2-0.30.30.4-0.40.5-0.4-0.50.50.50.30.5-0.4-0.5-0.30.50.2-0.5-0.50.5
Bone: maximum force0.51.15.7-0.60.50.5-0.60.5-0.7-0.80.91.10.91.0-0.7-1.0-0.81.11.1-1.3-1.32.4
Bone: maximum moment0.51.04.4-0.60.60.6-0.70.6-0.8-0.80.91.11.01.0-0.6-1.0-0.81.11.1-1.3-1.32.1
Mean time between licks in bursts0.74.45.1-2.02.12.2-2.22.2-2.2-2.22.22.02.12.1-2.3-2.1-2.02.12.0-2.1-2.11.4
Mean num. licks in bursts0.10.40.8-0.60.40.5-0.60.6-0.6-0.60.60.60.60.6-0.9-0.6-0.50.70.6-0.7-0.70.6
Cd content in liver5.15.710.12.5-1.9-2.32.4-2.62.42.4-2.4-2.7-2.4-2.23.22.32.6-2.3-2.42.22.3-1.4
Co content in liver3.23.74.41.9-1.7-1.81.9-1.81.91.9-2.0-1.9-1.9-1.92.12.02.0-2.0-1.92.02.1-1.9
Cu content in liver1.61.82.41.3-1.5-1.61.5-1.41.41.5-1.5-1.2-1.2-1.51.11.41.2-1.4-1.21.41.4-1.0
Fe content in liver3.74.65.32.2-2.3-2.22.2-2.12.22.2-2.2-1.9-2.0-2.21.92.22.0-2.2-2.02.22.2-1.8
K content in liver3.73.64.9-2.11.61.8-1.81.9-1.9-1.91.92.12.01.8-2.2-1.8-2.11.82.0-1.8-1.81.3
Mg content in liver0.50.50.8-0.90.60.7-0.70.8-0.7-0.70.70.90.90.6-0.8-0.6-0.90.60.9-0.6-0.60.2
Mn content in liver0.30.31.0-0.80.50.5-0.50.8-0.5-0.50.50.80.50.3-1.0-0.4-0.70.30.3-0.2-0.3-0.4
Na content in liver0.10.10.4-0.2-0.20.0-0.10.3-0.1-0.10.10.50.30.0-0.6-0.1-0.40.10.4-0.1-0.1-0.0
Rb content in liver5.76.68.7-2.62.22.5-2.52.6-2.6-2.62.62.82.62.5-2.9-2.6-2.72.62.6-2.5-2.61.9
Se content in liver0.20.30.5-0.70.40.5-0.50.7-0.5-0.50.50.70.60.5-0.7-0.5-0.70.50.5-0.4-0.50.3
Sr content in liver0.00.00.1-0.10.30.2-0.10.1-0.1-0.10.10.20.20.1-0.0-0.0-0.10.00.10.00.0-0.3
Zn content in liver0.00.00.1-0.00.10.00.0-0.10.10.1-0.1-0.00.1-0.00.30.00.1-0.1-0.00.10.1-0.0
Bone: minimum diameter0.50.93.3-0.50.80.7-0.70.7-0.8-0.90.91.00.81.0-0.7-1.0-0.71.10.8-1.2-1.21.8
Time in familiar zone, hab. session 10.20.20.80.2-0.2-0.20.2-0.20.30.3-0.4-0.6-0.6-0.40.50.40.4-0.5-0.60.50.6-0.9
Time in novel zone, hab. session 12.83.24.31.9-1.9-1.91.9-2.01.91.8-1.8-2.1-1.9-1.71.81.71.8-1.7-1.81.61.6-0.7
Total zone transitions, hab. session 10.81.12.6-0.90.90.8-0.90.9-0.9-1.01.01.11.01.1-1.0-1.1-1.01.21.1-1.2-1.21.6
Total locomotion distance, hab. session 11.31.86.6-0.91.10.9-1.00.9-1.1-1.21.31.41.01.4-1.0-1.4-1.11.51.1-1.7-1.72.6
Locomotion velocity, hab. session 12.53.67.2-1.51.71.6-1.61.5-1.7-1.81.92.21.81.9-1.6-2.0-1.72.01.8-2.2-2.22.7
Time in familiar zone, hab. session 20.20.31.00.3-0.4-0.40.4-0.20.40.4-0.4-1.0-0.8-0.40.30.50.5-0.5-0.70.50.5-0.7
Time in novel zone, hab. session 20.20.30.60.6-0.4-0.40.5-0.70.60.5-0.50.0-0.3-0.50.80.50.5-0.6-0.40.60.6-0.5
Total zone transitions, hab. session 20.00.00.10.1-0.1-0.10.0-0.00.00.0-0.10.10.2-0.1-0.10.1-0.0-0.10.20.10.1-0.3
Total locomotion distance, hab. session 20.10.10.9-0.10.20.2-0.20.1-0.3-0.30.30.40.30.4-0.3-0.4-0.20.40.3-0.5-0.60.9
Locomotion velocity, hab. session 20.30.41.4-0.30.40.4-0.50.4-0.5-0.60.60.60.50.6-0.6-0.7-0.50.70.6-0.8-0.81.2
Novel to familiar place preference ratio0.81.01.91.3-1.4-1.21.1-1.21.11.0-1.0-0.6-1.0-1.00.61.01.0-0.9-1.00.90.8-0.4
Novelty place preference1.01.22.11.3-1.5-1.31.2-1.21.21.1-1.1-0.7-1.1-1.20.71.11.1-1.1-1.21.01.0-0.7
Time in novel zone, NPP test1.41.62.61.5-1.6-1.41.4-1.41.31.3-1.3-0.9-1.3-1.30.91.31.3-1.3-1.31.21.2-0.9
Total zone transitions, NPP test0.30.40.8-0.70.90.7-0.70.6-0.7-0.70.70.30.80.6-0.6-0.6-0.70.60.8-0.6-0.60.2
Total locomotion distance, NPP test0.20.31.2-0.50.70.5-0.50.3-0.5-0.60.60.30.50.6-0.2-0.6-0.50.70.5-0.7-0.71.1
Locomotion velocity, NPP test0.60.91.6-0.91.10.9-0.90.7-0.9-0.91.00.80.91.0-0.7-1.0-0.91.00.8-1.1-1.11.3
Intraocular pressure0.10.10.30.10.1-0.10.1-0.30.20.2-0.20.2-0.2-0.30.60.30.3-0.3-0.30.40.4-0.5
Delta distance traveled before/after self-admin0.10.10.2-0.40.40.4-0.50.4-0.4-0.30.30.10.30.3-0.3-0.3-0.40.30.4-0.2-0.2-0.0
Delta ambulatory time before/after self-admin0.20.40.6-0.70.70.7-0.80.6-0.6-0.60.60.40.60.6-0.7-0.6-0.80.50.7-0.5-0.50.3
Parametrial fat weight0.00.10.4-0.30.40.5-0.40.4-0.3-0.30.20.00.40.2-0.0-0.20.00.10.20.00.0-0.6
Pavlov. Cond. lever latency2.93.75.0-2.12.22.1-2.11.9-2.0-2.12.01.81.52.1-1.5-2.0-1.82.01.5-2.0-1.91.6
Pavlov. Cond. magazine entry latency2.53.34.42.1-2.0-2.12.1-2.02.02.0-1.9-1.6-1.7-1.91.71.81.7-1.8-1.51.71.7-0.7
Pavlov. Cond. change in total contacts2.22.43.71.9-1.8-1.71.7-1.61.61.6-1.6-1.2-1.4-1.61.31.61.6-1.5-1.41.51.4-0.9
Pavlov. Cond. index score3.84.86.12.5-2.4-2.42.4-2.22.32.3-2.3-2.0-1.9-2.32.02.32.1-2.3-1.82.22.2-1.6
Pavlov. Cond. latency score3.64.55.82.4-2.4-2.42.3-2.22.22.3-2.2-2.0-1.8-2.21.82.22.0-2.2-1.82.12.1-1.5
Pavlov. Cond. lever contacts3.03.74.62.1-2.2-2.12.1-1.92.02.0-2.0-1.8-1.5-2.11.62.01.8-2.0-1.52.02.0-1.7
Pavlov. Cond. magazine entry number4.05.06.7-2.62.52.6-2.52.4-2.4-2.42.41.92.02.4-2.1-2.3-2.12.21.8-2.1-2.11.2
Pavlov. Cond. intertrial magazine entries0.00.10.1-0.20.20.3-0.30.2-0.3-0.30.30.20.10.3-0.2-0.3-0.20.30.1-0.3-0.30.2
Pavlov. Cond. lever-magazine prob. diff.3.23.95.02.2-2.2-2.22.2-2.02.12.1-2.1-1.8-1.7-2.11.72.11.9-2.0-1.62.02.0-1.4
Pavlov. Cond. response bias3.94.86.32.5-2.5-2.42.4-2.32.32.3-2.3-1.9-1.9-2.31.92.32.1-2.2-1.82.22.1-1.5
Pavlov. Cond. lever latency0.10.10.4-0.50.30.3-0.30.3-0.3-0.20.20.40.70.2-0.2-0.2-0.30.10.5-0.1-0.1-0.2
Pavlov. Cond. magazine entry latency0.20.30.70.8-0.4-0.50.5-0.80.60.5-0.5-0.4-0.7-0.40.90.40.7-0.4-0.50.40.40.1
Pavlov. Cond. change in total contacts0.41.12.21.3-1.0-1.01.0-1.21.00.9-0.9-1.2-1.5-0.91.30.91.2-0.8-1.30.70.7-0.0
Pavlov. Cond. index score0.20.30.70.8-0.5-0.50.5-0.70.50.4-0.4-0.6-0.8-0.30.70.30.6-0.3-0.70.20.20.4
Pavlov. Cond. latency score0.10.20.40.7-0.3-0.40.3-0.50.30.3-0.2-0.3-0.7-0.20.60.20.5-0.1-0.5-0.00.00.6
Pavlov. Cond. lever contacts0.30.51.20.9-0.7-0.70.7-0.80.70.6-0.6-0.8-1.1-0.60.70.60.8-0.5-1.00.50.5-0.1
Pavlov. Cond. magazine entry number0.40.61.1-1.00.60.8-0.81.0-0.7-0.70.70.80.90.7-1.0-0.7-0.90.60.7-0.6-0.60.0
Pavlov. Cond. intertrial magazine entries0.30.71.5-1.00.60.9-0.91.1-0.8-0.80.80.91.10.7-1.2-0.7-0.90.71.0-0.6-0.6-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.6-0.3-0.30.3-0.50.30.2-0.2-0.4-0.6-0.20.50.20.4-0.1-0.40.00.10.4
Pavlov. Cond. response bias0.30.51.10.9-0.7-0.80.7-0.80.70.6-0.6-0.8-1.1-0.50.60.50.7-0.4-0.90.30.30.3
Time in closed arm before self-admin1.22.03.21.6-1.7-1.51.5-1.61.41.4-1.4-1.6-1.4-1.31.81.31.6-1.2-1.51.11.2-0.3
Time in closed arm after self-admin0.10.10.40.6-0.4-0.40.4-0.50.30.3-0.3-0.4-0.1-0.30.50.30.4-0.2-0.20.20.20.4
Time in open arm before self-admin0.91.12.2-1.11.51.2-1.11.2-1.1-1.11.11.20.81.0-0.9-1.0-0.91.00.9-0.9-0.80.1
Time in open arm after self-admin0.70.81.70.9-1.0-1.11.1-0.90.90.8-0.8-1.1-1.3-0.80.70.70.9-0.6-1.00.50.50.0
Bone: periosteal estimation0.10.33.00.2-0.1-0.1-0.0-0.0-0.1-0.20.30.40.20.4-0.1-0.4-0.10.50.3-0.7-0.71.7
Bone: periosteal perimeter0.10.10.30.5-0.5-0.40.4-0.40.40.3-0.3-0.4-0.4-0.20.40.20.5-0.2-0.50.10.10.5
Bone: post-yield work0.10.21.90.2-0.0-0.10.0-0.0-0.1-0.10.20.80.50.20.0-0.3-0.30.30.7-0.5-0.51.4
Progressive ratio test 1 active lever presses0.00.10.3-0.20.50.3-0.30.3-0.2-0.20.20.40.10.2-0.1-0.1-0.10.1-0.1-0.00.0-0.4
Progressive ratio test 1 breakpoint0.00.00.2-0.30.40.3-0.30.3-0.2-0.20.20.30.00.1-0.1-0.1-0.10.1-0.1-0.00.0-0.3
Progressive ratio test 1 inactive lever presses0.51.32.3-1.31.21.3-1.31.5-1.2-1.21.11.31.41.1-1.4-1.1-1.21.01.1-0.9-0.90.1
Progressive ratio test 2 active lever presses0.00.00.1-0.10.20.1-0.10.1-0.0-0.00.00.40.1-0.00.00.0-0.0-0.1-0.10.10.1-0.2
Progressive ratio test 2 breakpoint0.00.00.2-0.10.10.1-0.10.00.10.0-0.00.30.1-0.10.10.10.0-0.2-0.10.20.2-0.4
Progressive ratio test 2 inactive lever presses0.00.00.3-0.20.30.2-0.10.2-0.1-0.00.00.20.1-0.0-0.00.0-0.1-0.1-0.00.10.1-0.5
Incentive Sensitization - Responses0.10.30.50.5-0.6-0.60.6-0.60.60.6-0.6-0.3-0.6-0.60.70.60.5-0.6-0.60.60.6-0.5
Incentive Sensitization - Breakpoint0.10.30.50.4-0.5-0.50.5-0.60.50.5-0.5-0.2-0.4-0.50.70.50.5-0.5-0.50.50.6-0.5
Sum of active levers in priming session hrs 5-61.41.32.31.3-1.5-1.51.3-1.31.21.2-1.2-1.2-1.2-1.20.81.11.1-1.0-1.00.90.9-0.0
Progressive ratio0.41.11.5-1.11.21.0-1.00.9-1.0-1.01.00.91.11.0-0.6-1.0-1.01.01.1-1.1-1.01.2
Food seeking constrained by brief footshock0.50.72.1-0.80.80.7-0.80.8-0.8-0.80.80.70.60.9-0.5-0.9-0.70.90.5-0.9-0.91.5
Seeking ratio, punishment vs. effort0.00.10.3-0.30.00.2-0.20.4-0.3-0.30.30.30.10.3-0.6-0.3-0.30.40.2-0.4-0.40.5
Retroperitoneal fat weight0.62.74.0-1.41.41.6-1.61.7-1.6-1.61.62.01.91.6-2.0-1.6-1.61.61.8-1.6-1.61.3
Reaction time number correct0.41.31.9-1.21.01.3-1.41.3-1.2-1.31.20.90.91.2-1.2-1.2-1.01.10.9-1.1-1.10.5
Reaction time mean minus median0.31.72.41.4-1.4-1.61.5-1.51.41.4-1.4-1.3-1.3-1.31.31.31.3-1.2-1.21.11.1-0.3
Reaction time mean minus median AUC0.31.72.21.4-1.3-1.51.4-1.41.41.4-1.4-1.5-1.4-1.31.31.31.2-1.2-1.21.21.2-0.5
Reaction time num false alarms2.74.67.1-2.52.72.4-2.42.2-2.3-2.32.21.82.12.2-2.0-2.2-2.22.12.0-2.0-2.01.0
Reaction time num false alarms AUC2.86.48.8-2.93.02.7-2.72.5-2.7-2.62.62.12.52.6-2.5-2.6-2.62.52.3-2.4-2.41.4
Reaction time trials correct on left0.41.31.9-1.21.01.3-1.41.3-1.2-1.31.20.90.91.2-1.2-1.2-1.01.10.9-1.1-1.10.5
Reaction time trials on left0.41.21.8-1.11.01.3-1.31.3-1.2-1.21.20.90.81.2-1.2-1.1-1.01.10.9-1.1-1.10.5
Reaction time mean2.25.07.82.4-2.8-2.82.6-2.52.42.5-2.4-2.3-1.9-2.41.92.32.0-2.1-1.62.01.9-0.7
Reaction time mean AUC1.84.46.92.3-2.6-2.62.5-2.42.32.3-2.3-2.1-1.8-2.21.72.21.8-2.0-1.51.91.8-0.8
Median of all reaction times3.35.18.62.4-2.9-2.82.7-2.62.52.5-2.4-2.3-1.8-2.41.82.31.9-2.2-1.62.02.0-0.9
Reaction time omissions1.01.72.21.0-1.1-1.21.3-1.41.31.3-1.3-1.5-1.2-1.31.41.31.2-1.3-1.21.41.4-1.3
Reaction time false alarm rate1.92.74.2-1.92.01.7-1.71.6-1.7-1.71.61.51.71.6-1.6-1.6-1.81.61.6-1.5-1.50.8
Reaction time premature initiation rate0.10.10.20.3-0.3-0.30.3-0.30.40.4-0.4-0.20.1-0.40.40.30.2-0.40.00.40.4-0.3
Reaction time premature initiations0.00.10.1-0.30.20.3-0.30.3-0.2-0.30.20.30.40.2-0.3-0.2-0.20.20.4-0.2-0.2-0.0
Std. dev. reaction times1.44.76.72.4-2.4-2.62.5-2.52.32.3-2.3-2.1-2.1-2.22.12.22.1-2.0-1.91.91.9-0.5
Reaction time trials completed0.41.21.8-1.11.01.3-1.31.3-1.2-1.21.20.90.81.2-1.2-1.1-1.01.10.9-1.1-1.10.5
Reaction time trials AUC0.31.01.6-1.01.01.2-1.21.2-1.1-1.11.10.80.81.1-1.1-1.0-0.91.00.8-1.0-1.00.4
Run reversals in cocaine runway, females1.01.11.8-1.11.20.8-0.91.0-1.0-1.01.10.90.81.0-1.3-1.1-1.01.20.7-1.2-1.31.2
Run reversals in cocaine runway, males0.91.01.4-1.21.11.1-1.11.1-1.1-1.01.00.31.21.1-0.9-1.0-1.01.01.1-1.0-1.00.6
Latency to leave start box in cocaine runway3.04.16.1-2.22.42.3-2.22.2-2.1-2.02.01.92.52.0-1.9-2.0-2.11.82.2-1.7-1.70.7
Latency to leave start box in cocaine runway, F1.21.52.7-1.51.61.5-1.41.4-1.3-1.31.20.91.51.2-1.1-1.1-1.21.01.3-0.9-0.8-0.2
Latency to leave start box in cocaine runway, M4.13.94.8-1.92.02.0-2.02.0-2.0-2.02.02.22.12.0-1.9-2.0-2.02.02.0-2.0-2.01.7
Std. dev. time between licks in bursts2.14.05.4-2.32.32.2-2.22.3-2.1-2.12.02.02.31.9-2.0-1.9-2.11.82.1-1.6-1.60.4
Total sessions with >9 infusions2.63.25.2-1.82.31.9-1.91.8-1.8-1.91.92.01.61.9-1.7-1.8-1.61.81.4-1.8-1.71.3
Short access day 1 total inactive lever presses1.83.65.6-1.92.42.0-2.02.0-1.9-2.01.91.91.62.0-1.4-2.0-1.82.01.7-2.0-1.91.7
Short access day 10 total inactive lever presses0.00.20.5-0.5-0.00.3-0.30.4-0.3-0.30.30.30.70.3-0.4-0.3-0.60.30.7-0.3-0.30.2
Short access day 1 total infusions2.04.05.5-1.92.31.9-2.12.0-2.0-2.02.02.31.52.0-2.0-2.0-2.02.01.6-2.0-2.02.1
Short access day 10 total infusions0.20.22.10.20.1-0.10.1-0.10.30.3-0.3-0.1-0.1-0.50.30.50.4-0.6-0.40.70.7-1.4
Short access total infusions0.20.30.8-0.50.90.6-0.60.6-0.5-0.50.50.90.50.5-0.5-0.5-0.40.40.3-0.3-0.3-0.0
Short access day 1 locomotion2.64.44.9-2.02.22.1-2.22.1-2.1-2.22.22.01.82.2-2.2-2.2-1.92.21.8-2.2-2.21.9
Short access day 10 total locomotion0.10.20.7-0.40.80.7-0.60.5-0.5-0.60.50.00.40.60.0-0.5-0.20.50.4-0.5-0.4-0.1
Short access total locomotion1.92.95.0-1.72.21.9-1.81.8-1.8-1.81.81.61.41.8-1.6-1.8-1.51.81.5-1.7-1.70.9
One hour access (0.3 mA shock)0.30.30.50.5-0.5-0.50.4-0.70.60.6-0.6-0.4-0.3-0.60.70.60.5-0.6-0.50.70.7-0.6
Compulsive drug intake0.81.21.8-1.11.11.2-1.21.1-1.1-1.11.10.91.21.1-0.9-1.1-1.01.11.3-1.0-1.00.9
One hour access (shock baseline)0.30.91.40.8-0.7-0.80.9-1.01.00.9-0.9-0.7-0.9-0.91.21.00.9-1.0-1.01.01.0-0.9
Social response proportion0.30.40.60.5-0.8-0.80.7-0.60.70.7-0.7-0.8-0.7-0.70.50.70.5-0.6-0.60.60.6-0.4
Social responses0.00.00.2-0.10.40.2-0.1-0.0-0.1-0.10.1-0.50.10.20.3-0.1-0.00.10.0-0.2-0.10.2
Social time1.62.53.91.5-1.5-1.61.6-1.61.61.6-1.6-2.0-1.5-1.61.51.61.4-1.6-1.51.61.6-1.5
Soleus weight1.74.96.0-2.02.12.2-2.22.1-2.2-2.22.22.42.42.3-2.1-2.3-2.02.32.3-2.3-2.32.1
Bone: stiffness1.01.87.2-0.90.80.8-0.90.8-1.1-1.21.21.51.11.3-1.0-1.4-1.21.51.3-1.7-1.72.7
Tibialis anterior weight4.314.619.1-3.93.64.0-4.04.1-4.0-3.93.94.44.23.8-4.2-3.8-3.83.73.9-3.5-3.62.1
Time to tail flick, vehicle, before self-admin0.10.10.80.3-0.3-0.10.2-0.30.30.3-0.3-0.4-0.0-0.30.60.30.5-0.4-0.20.40.5-0.9
Time to tail flick, vehicle, after self-admin0.61.11.71.2-1.3-1.01.1-1.01.01.1-1.1-0.8-0.8-1.10.91.11.0-1.1-0.71.11.1-1.2
Time to tail flick, test, before self-admin2.83.24.4-1.91.61.8-1.91.7-1.8-1.81.81.72.01.8-1.7-1.8-1.91.72.1-1.7-1.71.3
Time to tail flick, test, after self-admin3.33.54.3-1.91.71.9-1.91.9-2.0-1.91.91.52.01.9-1.9-1.9-2.01.92.1-1.9-1.91.3
Delta time to tail flick, vehicle, before/after SA0.20.30.40.6-0.6-0.60.6-0.50.50.6-0.6-0.2-0.5-0.60.20.50.4-0.5-0.40.50.5-0.3
Delta time to tail flick, test, before/after SA0.10.20.40.5-0.4-0.30.4-0.30.40.4-0.4-0.6-0.3-0.30.50.30.5-0.3-0.50.30.3-0.4
Tibia length0.30.74.91.1-1.1-1.10.9-1.00.70.5-0.4-0.4-0.9-0.30.60.20.6-0.0-0.5-0.3-0.32.2
Ambulatory time before self-admin0.61.82.61.6-1.6-1.61.5-1.61.41.4-1.3-1.1-1.6-1.21.41.21.4-1.1-1.51.01.00.2
Ambulatory time after self-admin0.30.40.70.8-0.7-0.70.7-0.80.70.7-0.7-0.7-0.9-0.60.60.60.5-0.6-0.70.50.5-0.0
Bone: tissue strength0.00.00.20.10.1-0.10.2-0.20.20.1-0.1-0.3-0.1-0.10.40.10.2-0.1-0.20.10.10.1
Total heroin consumption1.61.92.61.3-1.6-1.51.5-1.41.41.5-1.5-1.3-1.0-1.51.01.51.3-1.5-1.21.51.5-1.2
Bone: trabecular number0.91.72.61.5-1.1-1.41.4-1.41.41.3-1.3-1.4-1.6-1.21.41.21.5-1.2-1.61.11.1-0.5
Bone: trabecular spacing1.11.72.2-1.30.91.1-1.21.3-1.3-1.21.21.41.41.2-1.5-1.3-1.51.31.5-1.3-1.31.1
Bone: trabecular thickness6.18.510.53.1-2.8-2.92.9-3.03.02.9-2.9-2.9-3.1-2.93.22.93.0-2.9-3.02.82.8-2.0
Bone: trabecular tissue density0.00.10.60.2-0.10.0-0.10.0-0.1-0.20.20.6-0.00.2-0.1-0.2-0.10.30.1-0.3-0.30.8
Water consumed over 24 hours0.00.10.40.10.10.1-0.0-0.10.10.1-0.1-0.2-0.1-0.10.40.20.2-0.2-0.10.30.3-0.6
Number of responses in last shaping day0.00.00.20.1-0.3-0.10.10.00.10.1-0.1-0.10.1-0.1-0.30.10.0-0.10.20.20.1-0.5