Vom2r36

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	alternative TSS	XM_063271848.1	0.12	0.08	7.1e-04	0.01	0.01	0.01	0.01	1.1e-02	6.8e-03	2.4e-02	6.5e-02
2	Adipose	alternative TSS	NM_001099483.1	0.12	0.08	7.8e-04	0.01	0.02	0.01	0.01	8.7e-03	6.3e-03	2.1e-02	5.4e-02
3	Adipose	gene expression	Vom2r36	0.39	0.15	0.0e+00	0.16	0.16	0.16	0.16	7.9e-17	5.8e-17	5.9e-17	2.9e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3
Bone: apparent density	0.1	0.1	0.2	-0.4	0.4	0.1
Area under the delay curve	0.9	1.4	1.8	-1.3	1.3	-0.8
BMI with tail	0.5	1.6	2.5	-1.0	1.1	-1.6
BMI without tail	0.0	0.0	0.0	0.1	-0.1	-0.1
Body weight	0.7	3.0	4.4	1.5	-1.6	2.1
Weight adjusted by age	0.2	0.5	0.6	-0.7	0.6	0.8
Bone surface	1.6	3.1	5.1	1.4	-1.5	2.3
Bone volume	1.5	2.9	4.4	1.4	-1.5	2.1
Breakpoint value in progressive ratio session	0.1	0.1	0.4	-0.1	0.1	-0.6
Number of licking bursts	0.1	0.2	0.2	0.5	-0.5	0.1
Context. condit. distance diff. score	0.5	0.6	0.9	-1.0	0.9	-0.3
Locomotion velocity, session 1	0.4	0.4	0.4	-0.7	0.6	0.7
Locomotion distance, session 1	1.0	1.3	3.8	-0.1	-0.1	2.0
Locomotion velocity, session 2	0.1	0.2	0.2	-0.5	0.5	0.1
Locomotion distance, session 2	1.1	1.5	2.9	0.9	-1.0	1.7
Locomotion velocity, session 3	0.0	0.1	0.1	0.3	-0.3	0.0
Locomotion distance, session 3	0.4	0.4	0.7	-0.8	0.8	0.2
Stereotopy head waving bouts, day 3	0.1	0.2	0.3	0.5	-0.5	0.0
Stereotopy head waving duration, day 3	0.2	0.3	0.4	0.6	-0.6	0.1
Locomotion velocity, session 7	0.2	0.2	0.4	0.4	-0.4	0.6
Locomotion distance, session 7	0.0	0.0	0.1	-0.2	0.1	0.3
Stereotopy head waving bouts, day 7	0.5	0.6	0.8	0.9	-0.9	0.5
Stereotopy head waving duration, day 7	0.3	0.4	0.5	0.7	-0.7	0.5
Locomotion velocity, session 8	0.1	0.2	0.2	-0.5	0.4	0.3
Locomotion distance, session 8	0.2	0.3	0.4	-0.6	0.5	0.4
Degree of sensitization distance	0.1	0.1	0.1	0.3	-0.3	0.2
Degree of sensitization stereotypy	0.0	0.0	0.0	0.2	-0.1	-0.0
Conditioned locomotion	0.3	0.3	0.5	-0.7	0.7	0.0
Cocaine response after cond. corrected	1.5	2.2	3.2	1.8	-1.6	-0.8
Cocaine response after cond. not corrected	1.6	2.3	3.5	1.9	-1.8	0.5
Cocaine response before conditioning	1.7	2.0	6.1	-0.1	-0.1	2.5
Saline control response	0.2	0.3	0.4	-0.6	0.6	0.5
Bone: connectivity density	0.3	0.5	0.6	-0.8	0.8	-0.6
Bone: cortical apparent density	0.1	0.2	0.2	0.5	-0.5	0.2
Bone: cortical area	0.3	0.5	0.7	-0.7	0.6	0.8
Bone: cortical porosity	0.1	0.1	0.4	-0.1	0.1	-0.6
Bone: cortical porosity	0.2	0.2	0.3	0.5	-0.5	-0.3
Bone: cortical thickness	0.7	1.2	1.7	-1.3	1.3	-0.7
Bone: cortical thickness	0.1	0.1	0.2	0.1	-0.2	0.4
Bone: cortical tissue density	0.2	0.2	0.3	0.6	-0.6	0.2
Condit. Reinf. active minus inactive responses	0.4	0.4	0.7	0.8	-0.8	0.1
Condit. Reinf. active-inactive response ratio	0.4	0.5	1.0	-0.4	0.5	-1.0
Condit. Reinf. active responses	1.2	1.5	2.0	1.4	-1.4	0.8
Condit. Reinf. inactive responses	2.1	2.7	3.7	1.5	-1.5	1.9
Incentive salience index mean	0.4	0.5	0.6	0.7	-0.8	0.7
Condit. Reinf. lever presses	0.3	0.5	1.1	0.4	-0.4	1.1
Condit. Reinf. active minus inactive responses	1.1	1.7	4.1	0.6	-0.8	2.0
Condit. Reinf. active-inactive response ratio	1.7	2.7	4.7	1.3	-1.4	2.2
Condit. Reinf. active responses	0.8	1.2	3.5	-0.1	-0.1	1.9
Condit. Reinf. inactive responses	0.7	1.0	1.6	-1.3	1.2	-0.0
Condit. Reinf. lever presses	0.4	0.5	0.9	-0.9	0.9	-0.0
Condit. Reinf. lever reinforcers received	1.1	1.5	4.4	0.1	-0.2	2.1
Conditioned reinforcement - actives	0.6	2.5	3.7	1.9	-1.9	0.6
Conditioned reinforcement - inactives	0.8	2.2	3.6	1.2	-1.3	1.9
Conditioned locomotion	0.7	1.0	1.5	1.2	-1.2	0.3
Patch foraging indifference point 0 sec	1.3	3.7	5.3	-2.3	2.3	-0.8
Patch foraging indifference point AUC	0.2	0.4	1.1	0.0	0.0	-1.1
Delay disc. indifference point, 0s delay	3.9	4.4	6.8	-2.6	2.5	-0.2
Delay disc. indifference point, 16s delay	0.8	1.2	1.6	1.3	-1.1	-0.8
Delay disc. indifference point, 2s delay	0.8	0.9	1.2	-1.1	1.1	-0.5
Delay disc. indifference point, 24s delay	0.2	0.4	0.5	0.7	-0.6	-0.6
Delay disc. indifference point, 4s delay	0.0	0.0	0.1	-0.1	0.1	0.3
Delay disc. indifference point, 8s delay	1.2	2.0	2.8	-1.7	1.6	-0.8
Indifference point function ln k	1.1	3.4	9.6	0.5	-0.7	3.1
Indifference point function log k	1.1	3.4	9.6	0.5	-0.7	3.1
Patch foraging total patch changes 0 sec	1.2	3.6	5.2	-2.3	2.2	-0.8
Patch foraging total patch changes 12 sec	0.3	0.4	0.9	-0.4	0.5	-1.0
Patch foraging total patch changes 18 sec	0.7	1.6	1.9	-1.4	1.4	-1.1
Patch foraging total patch changes 24 sec	0.2	0.8	1.2	1.1	-1.0	-0.2
Patch foraging total patch changes 6 sec	0.6	1.1	1.9	-0.7	0.8	-1.4
Patch foraging time to switch 0 sec	1.2	4.8	6.2	2.5	-2.2	-1.8
Patch foraging water rate 0 sec	0.5	1.7	2.5	-1.6	1.4	0.8
Patch foraging water rate 12 sec	0.6	2.5	2.9	-1.7	1.5	1.6
Patch foraging water rate 18 sec	0.5	1.0	1.3	-1.1	1.0	0.9
Patch foraging water rate 24 sec	0.4	0.5	1.1	-0.5	0.4	1.1
Patch foraging water rate 6 sec	3.8	5.6	10.7	1.7	-1.8	3.3
Seeking ratio, delayed vs. immediate footshock	4.3	6.1	9.6	-3.1	3.0	-0.3
Distance traveled before self-admin	2.1	4.6	6.5	-2.5	2.3	1.4
Distance traveled after self-admin	6.4	11.2	17.0	-4.1	4.0	-0.9
Extensor digitorum longus weight	0.0	0.2	0.4	0.1	-0.2	0.7
Bone: elastic displacement	1.2	1.5	1.9	-1.4	1.4	-0.9
Bone: elastic work	1.0	1.3	2.1	-1.5	1.4	0.2
Bone: endosteal estimation	1.5	3.6	5.9	1.5	-1.6	2.4
Bone: endosteal perimeter	0.5	1.3	2.9	0.6	-0.7	1.7
Epididymis fat weight	0.3	1.6	2.5	1.6	-1.5	-0.1
Delta time in closed arm before/after self-admin	0.2	0.2	0.2	-0.5	0.5	-0.4
Delta time in open arm before/after self-admin	0.8	0.9	1.6	0.7	-0.8	1.3
Diff in mean of infusions in LGA sessions	0.7	1.2	2.0	-1.4	1.3	0.1
Delay discount exponential model param	0.8	1.1	1.5	1.2	-1.2	0.7
Extinction: sum of active levers before priming	0.1	0.2	0.3	-0.6	0.6	-0.1
Active lever presses in extinction session 6	2.9	3.0	4.7	2.2	-2.0	-0.2
Bone: final force	0.8	1.3	3.4	0.4	-0.6	1.8
Bone: final moment	0.9	1.5	4.2	0.3	-0.4	2.1
Food consumed during 24 hour testing period	0.2	0.5	1.3	0.2	-0.3	1.2
Glucose	2.1	3.3	3.8	-1.9	2.0	-1.5
Heart weight	0.7	1.1	1.3	1.0	-1.0	1.1
Delay discount hyperbolic model param	1.2	1.6	2.1	1.4	-1.4	0.8
Intermittent access intake day 1-15 change	0.4	2.0	2.4	1.5	-1.5	1.2
Intermittent access intake escalation	0.7	3.7	4.4	2.1	-2.1	1.5
Intermittent access intake escalation 2	0.1	0.1	0.3	-0.3	0.3	0.5
Intermitt. access day 1 inactive lever presses	0.5	6.1	7.8	2.8	-2.8	1.6
Intermitt. access day 15 inactive lever presses	1.1	6.0	7.5	2.7	-2.7	1.8
Intermitt. access escalation Index	0.1	0.3	0.6	-0.3	0.4	-0.7
Intermittent access day 1 total infusions	0.4	1.3	1.8	1.3	-1.3	0.6
Intermittent access day 15 total infusions	2.0	5.0	6.8	2.6	-2.6	1.2
Intermittent access terminal intake (last 3 days)	1.9	3.3	4.4	2.1	-2.1	1.1
Intermittent access total infusions	3.6	4.2	5.5	2.3	-2.3	1.3
Intermittent access day 1 locomotion	1.4	2.5	3.1	1.7	-1.7	1.2
Intermittent access day 15 total locomotion	0.2	0.6	1.6	0.2	-0.4	1.3
Intermittent access total locomotion	3.6	4.3	4.5	2.1	-2.1	2.0
Intermittent access standard deviation	0.0	0.2	0.2	-0.4	0.4	-0.5
Left kidney weight	1.7	13.3	23.5	2.7	-3.0	4.9
Right kidney weight	2.2	15.3	22.2	3.3	-3.5	4.7
Cocaine induced anxiety	0.6	1.6	1.7	1.2	-1.2	1.3
Post-drug Anxiety	2.6	3.0	4.1	2.0	-2.0	0.9
Baseline Anxiety	0.2	0.4	0.8	-0.4	0.5	-0.9
Tail length	1.2	6.6	11.6	1.9	-2.1	3.4
Length with tail	2.6	11.4	14.3	3.1	-3.2	3.8
Length without tail	2.2	11.4	14.0	3.7	-3.7	2.5
Times rat made contact with spout	0.4	0.5	0.5	-0.7	0.7	-0.6
Lifetime Intake	2.6	3.2	4.3	2.1	-2.1	1.1
Liver weight, left	1.0	1.7	2.4	1.1	-1.2	1.5
Liver weight, right	0.2	0.4	0.6	-0.8	0.8	-0.1
Locomotor activity	0.3	0.5	0.5	-0.7	0.7	-0.7
Locomotor testing distance	0.1	0.1	0.2	0.4	-0.4	-0.1
Locomotor testing rearing	0.0	0.1	0.2	0.0	-0.0	0.4
Locomotion in novel chamber	0.5	0.7	1.0	-0.7	0.7	-1.0
Locomotion in novel chamber post-restriction	0.4	1.2	1.3	-1.1	1.1	-1.0
Fecal boli incidents, locomotor time 1	0.1	0.3	0.4	-0.6	0.6	0.3
Change in fecal boli incidents, locomotor task	2.1	2.2	2.8	-1.3	1.4	-1.7
Time >=10cm from walls, locomotor time 1	0.2	0.3	0.5	0.7	-0.6	-0.2
Bouts of movement, locomotor time 1	2.6	3.4	5.4	-2.3	2.2	0.3
Total resting periods, locomotor time 1	1.6	1.8	2.9	-1.7	1.6	-0.1
Rest time, locomotor task time 1	0.4	0.6	1.0	0.6	-0.6	1.0
Distance moved, locomotor task time 1	0.3	0.8	1.2	-0.7	0.8	-1.1
Vertical activity count, locomotor time 1	1.1	7.8	10.2	-3.2	3.2	-1.8
Time >=10cm from walls, locomotor time 2	0.2	0.4	0.6	0.6	-0.5	-0.8
Bouts of movement, locomotor time 2	0.0	0.0	0.1	-0.2	0.2	-0.1
Total resting periods, locomotor time 2	0.0	0.1	0.2	-0.4	0.4	0.0
Rest time, locomotor task time 2	0.8	1.4	2.2	-1.5	1.4	-0.1
Distance moved, locomotor task time 2	0.0	0.1	0.1	-0.2	0.2	-0.3
Vertical activity count, locomotor time 2	0.7	1.5	2.2	-1.5	1.4	-0.6
Light reinforcement 1	0.3	1.6	2.5	-1.6	1.5	0.1
Light reinforcement 2	0.1	0.3	0.6	-0.4	0.4	-0.8
Bone: marrow area	1.4	3.5	5.8	1.5	-1.6	2.4
Bone: maximum diameter	0.2	0.3	0.8	-0.3	0.2	0.9
Bone: maximum force	0.6	1.2	3.4	0.1	-0.3	1.8
Bone: maximum moment	0.7	1.4	4.0	-0.0	-0.1	2.0
Mean time between licks in bursts	0.2	1.5	1.8	-1.4	1.3	-0.9
Mean num. licks in bursts	0.2	0.5	0.6	-0.8	0.8	-0.4
Cd content in liver	1.1	1.2	1.3	1.1	-1.1	1.1
Co content in liver	0.9	1.1	1.1	1.0	-1.1	1.1
Cu content in liver	3.8	4.5	5.6	2.4	-2.4	1.6
Fe content in liver	2.0	2.5	3.4	1.8	-1.8	1.0
K content in liver	0.1	0.1	0.2	0.5	-0.5	0.1
Mg content in liver	0.6	0.7	1.1	1.0	-1.0	-0.1
Mn content in liver	0.3	0.3	0.6	0.7	-0.7	-0.1
Na content in liver	0.4	0.5	1.4	-0.1	0.2	-1.2
Rb content in liver	4.4	5.1	5.7	2.4	-2.4	2.0
Se content in liver	1.1	1.2	2.5	-0.7	0.8	-1.6
Sr content in liver	13.2	11.4	13.8	-3.7	3.7	-2.6
Zn content in liver	1.5	1.7	2.6	1.6	-1.5	-0.6
Bone: minimum diameter	0.7	1.3	4.0	-0.0	-0.1	2.0
Time in familiar zone, hab. session 1	1.3	1.4	2.4	-1.0	0.8	1.5
Time in novel zone, hab. session 1	1.4	1.6	2.1	1.4	-1.3	-1.0
Total zone transitions, hab. session 1	0.4	0.6	1.9	-0.1	0.0	1.4
Total locomotion distance, hab. session 1	1.0	1.4	2.2	-1.5	1.4	0.3
Locomotion velocity, hab. session 1	0.6	0.8	1.3	-1.1	1.0	0.3
Time in familiar zone, hab. session 2	2.2	2.5	2.8	1.6	-1.7	1.5
Time in novel zone, hab. session 2	0.4	0.4	1.0	-0.4	0.4	-1.0
Total zone transitions, hab. session 2	0.8	1.1	2.2	-0.8	0.6	1.5
Total locomotion distance, hab. session 2	2.4	3.2	5.0	-2.2	2.1	-0.3
Locomotion velocity, hab. session 2	3.0	4.0	6.1	-2.5	2.4	-0.5
Novel to familiar place preference ratio	0.6	0.7	1.1	-1.0	1.0	-0.2
Novelty place preference	0.2	0.3	0.4	-0.6	0.6	0.2
Time in novel zone, NPP test	0.1	0.1	0.2	-0.4	0.4	0.2
Total zone transitions, NPP test	0.4	0.6	0.9	-0.9	0.8	0.3
Total locomotion distance, NPP test	1.3	1.8	2.7	-1.7	1.6	-0.3
Locomotion velocity, NPP test	1.5	2.1	3.3	-1.8	1.7	-0.2
Intraocular pressure	0.2	0.3	0.4	0.6	-0.6	0.3
Delta distance traveled before/after self-admin	2.2	2.4	2.9	-1.5	1.5	-1.7
Delta ambulatory time before/after self-admin	1.3	2.2	2.3	-1.4	1.5	-1.5
Parametrial fat weight	2.0	4.7	5.2	-2.1	2.1	-2.3
Pavlov. Cond. lever latency	0.0	0.0	0.0	0.2	-0.2	-0.0
Pavlov. Cond. magazine entry latency	0.9	1.1	1.6	-0.9	1.0	-1.2
Pavlov. Cond. change in total contacts	0.3	0.3	0.4	-0.6	0.6	-0.5
Pavlov. Cond. index score	0.5	0.6	0.7	-0.8	0.8	-0.7
Pavlov. Cond. latency score	0.5	0.6	0.7	-0.8	0.9	-0.7
Pavlov. Cond. lever contacts	0.0	0.0	0.0	0.1	-0.1	0.0
Pavlov. Cond. magazine entry number	0.6	0.8	0.8	0.9	-0.9	0.9
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.3	-0.5	0.5	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.6	0.6	-0.8	0.8	-0.7
Pavlov. Cond. response bias	0.1	0.1	0.2	-0.2	0.2	-0.5
Pavlov. Cond. lever latency	3.8	5.4	7.1	2.7	-2.6	1.5
Pavlov. Cond. magazine entry latency	1.9	2.7	2.9	-1.6	1.7	-1.6
Pavlov. Cond. change in total contacts	0.9	2.2	3.4	-1.9	1.8	-0.2
Pavlov. Cond. index score	1.8	2.9	3.8	-2.0	1.9	-1.1
Pavlov. Cond. latency score	2.4	3.8	4.6	-2.1	2.1	-1.5
Pavlov. Cond. lever contacts	2.9	4.3	5.9	-2.4	2.4	-1.2
Pavlov. Cond. magazine entry number	1.3	1.7	1.8	1.3	-1.4	1.2
Pavlov. Cond. intertrial magazine entries	2.0	4.5	6.2	1.8	-1.9	2.5
Pavlov. Cond. lever-magazine prob. diff.	1.9	2.9	3.7	-1.9	1.9	-1.1
Pavlov. Cond. response bias	1.7	2.4	3.5	-1.9	1.8	-0.5
Time in closed arm before self-admin	0.5	0.9	1.2	0.8	-0.9	1.1
Time in closed arm after self-admin	0.4	0.5	0.7	0.8	-0.8	0.4
Time in open arm before self-admin	2.4	2.9	3.2	-1.7	1.8	-1.6
Time in open arm after self-admin	0.5	0.6	0.7	-0.8	0.8	-0.6
Bone: periosteal estimation	0.6	1.4	3.7	0.4	-0.5	1.9
Bone: periosteal perimeter	0.5	1.0	2.6	0.4	-0.5	1.6
Bone: post-yield work	2.2	3.8	4.1	2.0	-2.0	1.9
Progressive ratio test 1 active lever presses	0.1	0.2	0.6	-0.2	0.1	0.8
Progressive ratio test 1 breakpoint	0.1	0.2	0.6	-0.3	0.2	0.8
Progressive ratio test 1 inactive lever presses	1.6	4.1	4.2	2.0	-2.1	2.0
Progressive ratio test 2 active lever presses	2.0	2.9	4.0	2.0	-2.0	0.8
Progressive ratio test 2 breakpoint	2.7	3.4	4.8	2.2	-2.2	0.9
Progressive ratio test 2 inactive lever presses	1.6	5.0	5.2	2.2	-2.3	2.2
Incentive Sensitization - Responses	2.4	6.6	9.0	3.0	-3.0	1.4
Incentive Sensitization - Breakpoint	2.6	5.9	8.3	2.9	-2.8	1.1
Sum of active levers in priming session hrs 5-6	0.6	0.5	0.8	-0.9	0.9	0.1
Progressive ratio	0.5	1.6	2.4	-1.5	1.5	-0.4
Food seeking constrained by brief footshock	23.8	29.7	46.7	-6.8	6.5	-0.4
Seeking ratio, punishment vs. effort	0.6	1.4	2.0	-1.4	1.3	0.8
Retroperitoneal fat weight	1.7	7.7	19.1	-1.2	1.5	-4.4
Reaction time number correct	0.9	3.1	3.9	-2.0	2.0	-1.2
Reaction time mean minus median	0.1	0.5	0.7	0.9	-0.8	0.1
Reaction time mean minus median AUC	0.1	0.6	1.0	1.0	-1.0	0.1
Reaction time num false alarms	0.0	0.1	0.1	-0.3	0.3	0.0
Reaction time num false alarms AUC	0.4	0.9	1.3	-1.1	1.1	-0.4
Reaction time trials correct on left	0.9	3.1	3.9	-2.0	2.0	-1.2
Reaction time trials on left	0.9	3.0	3.9	-2.0	1.9	-1.2
Reaction time mean	2.4	5.3	7.3	2.7	-2.7	1.3
Reaction time mean AUC	1.8	4.3	6.3	2.5	-2.4	0.8
Median of all reaction times	3.5	5.5	7.6	2.8	-2.7	1.3
Reaction time omissions	0.1	0.1	0.2	-0.5	0.4	0.1
Reaction time false alarm rate	0.0	0.0	0.1	-0.1	0.1	0.3
Reaction time premature initiation rate	0.0	0.0	0.0	-0.1	0.1	0.0
Reaction time premature initiations	0.3	1.0	1.2	-1.1	1.1	-0.7
Std. dev. reaction times	0.7	2.3	3.1	1.8	-1.7	0.8
Reaction time trials completed	0.9	3.0	3.9	-2.0	1.9	-1.2
Reaction time trials AUC	0.8	2.9	3.6	-1.9	1.9	-1.2
Run reversals in cocaine runway, females	1.0	1.1	1.6	1.3	-1.2	0.5
Run reversals in cocaine runway, males	0.6	0.6	0.9	0.9	-0.9	0.3
Latency to leave start box in cocaine runway	0.6	0.8	0.9	0.8	-0.9	1.0
Latency to leave start box in cocaine runway, F	0.1	0.1	0.1	0.2	-0.2	0.4
Latency to leave start box in cocaine runway, M	2.6	2.5	2.7	1.6	-1.6	1.5
Std. dev. time between licks in bursts	0.5	0.9	1.5	-1.2	1.1	-0.0
Total sessions with >9 infusions	1.2	1.5	1.9	1.1	-1.2	1.4
Short access day 1 total inactive lever presses	2.2	4.4	5.8	2.4	-2.4	1.3
Short access day 10 total inactive lever presses	0.1	0.4	0.4	0.6	-0.6	0.7
Short access day 1 total infusions	0.2	0.4	0.5	0.7	-0.7	0.4
Short access day 10 total infusions	0.1	0.1	0.2	0.4	-0.4	-0.0
Short access total infusions	0.0	0.0	0.1	0.2	-0.2	-0.1
Short access day 1 locomotion	2.5	4.2	5.8	2.4	-2.4	1.1
Short access day 10 total locomotion	0.2	0.6	1.9	0.0	-0.1	1.4
Short access total locomotion	0.4	0.6	0.8	-0.9	0.8	0.7
One hour access (0.3 mA shock)	6.9	8.2	9.7	3.1	-3.1	2.3
Compulsive drug intake	2.1	3.2	3.6	1.8	-1.9	1.6
One hour access (shock baseline)	1.3	3.3	5.0	2.2	-2.2	0.6
Social response proportion	4.1	5.2	7.0	2.6	-2.6	1.3
Social responses	6.1	7.9	9.0	3.0	-3.0	2.5
Social time	1.0	1.6	4.5	-0.4	0.2	2.1
Soleus weight	0.2	0.5	0.8	-0.9	0.8	-0.1
Bone: stiffness	1.2	2.2	4.0	1.1	-1.2	2.0
Tibialis anterior weight	1.7	6.0	6.6	-2.5	2.6	-2.2
Time to tail flick, vehicle, before self-admin	0.4	0.5	0.8	-0.9	0.8	0.3
Time to tail flick, vehicle, after self-admin	1.9	3.9	5.3	2.3	-2.3	1.2
Time to tail flick, test, before self-admin	5.3	6.1	9.6	-3.1	2.9	-0.1
Time to tail flick, test, after self-admin	0.1	0.1	0.3	-0.2	0.2	-0.5
Delta time to tail flick, vehicle, before/after SA	2.4	2.5	3.9	2.0	-1.9	0.4
Delta time to tail flick, test, before/after SA	2.7	3.3	5.2	2.3	-2.2	0.1
Tibia length	1.4	3.9	9.0	1.1	-1.3	3.0
Ambulatory time before self-admin	0.9	2.7	3.5	-1.9	1.7	1.3
Ambulatory time after self-admin	4.7	7.5	11.8	-3.4	3.3	-0.2
Bone: tissue strength	2.8	2.9	4.6	-2.1	2.0	-0.0
Total heroin consumption	0.3	0.3	0.5	-0.7	0.7	-0.2
Bone: trabecular number	0.7	1.3	1.7	-1.3	1.3	-0.8
Bone: trabecular spacing	0.0	0.0	0.0	-0.2	0.2	-0.0
Bone: trabecular thickness	0.1	0.1	0.2	0.4	-0.4	0.0
Bone: trabecular tissue density	0.8	1.3	1.9	1.4	-1.2	-0.8
Water consumed over 24 hours	0.2	0.4	0.8	-0.5	0.4	0.9
Number of responses in last shaping day	2.9	3.7	5.6	2.4	-2.3	0.6