Vom2r36

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	alternative TSS	NM_001099483.1	0.12	0.08	7.3e-04	0.01	0.01	0.01	0	1.8e-02	1.2e-02	1.8e-02	7.3e-02
2	Adipose	alternative TSS	XM_039088257.1	0.12	0.08	8.2e-04	0.01	0.01	0.01	0	2.6e-02	1.6e-02	6.5e-02	1.2e-01
3	Adipose	gene expression	Vom2r36	0.41	0.15	0.0e+00	0.15	0.15	0.15	0.15	4.3e-16	1.0e-16	2.0e-16	1.1e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3
Bone: apparent density	0.1	0.2	0.3	0.6	-0.5	-0.1
Area under the delay curve	2.3	2.5	2.8	1.7	-1.7	-1.3
BMI with tail	0.6	1.8	3.5	1.0	-1.0	-1.9
BMI without tail	1.4	2.9	3.8	1.9	-2.0	-1.2
Body weight	0.2	0.9	0.9	-1.0	0.9	0.9
Weight adjusted by age	0.3	0.4	0.6	0.5	-0.5	0.8
Bone surface	1.6	2.7	5.3	-1.2	1.2	2.3
Bone volume	1.4	2.4	4.1	-1.2	1.2	2.0
Breakpoint value in progressive ratio session	1.4	1.5	1.7	1.2	-1.3	-1.3
Number of licking bursts	0.4	0.4	0.5	-0.7	0.7	0.5
Context. condit. distance diff. score	0.9	1.1	1.4	1.2	-1.2	-0.8
Locomotion velocity, session 1	0.2	0.2	0.3	0.5	-0.5	0.4
Locomotion distance, session 1	0.8	1.0	3.1	-0.0	-0.0	1.8
Locomotion velocity, session 2	0.0	0.0	0.0	0.2	-0.2	0.2
Locomotion distance, session 2	1.4	2.0	3.8	-1.1	1.1	1.9
Locomotion velocity, session 3	0.1	0.1	0.1	-0.3	0.4	0.1
Locomotion distance, session 3	0.5	0.6	0.9	1.0	-0.9	-0.2
Stereotopy head waving bouts, day 3	0.1	0.2	0.3	-0.5	0.5	0.1
Stereotopy head waving duration, day 3	0.4	0.5	0.7	-0.8	0.8	0.4
Locomotion velocity, session 7	0.2	0.3	0.5	-0.4	0.4	0.7
Locomotion distance, session 7	0.1	0.1	0.1	0.3	-0.3	0.1
Stereotopy head waving bouts, day 7	0.6	0.6	0.8	-0.9	0.9	0.6
Stereotopy head waving duration, day 7	0.5	0.7	0.7	-0.9	0.9	0.7
Locomotion velocity, session 8	0.1	0.1	0.2	0.5	-0.5	0.2
Locomotion distance, session 8	0.2	0.2	0.3	0.6	-0.6	0.2
Degree of sensitization distance	0.1	0.1	0.1	-0.4	0.3	0.3
Degree of sensitization stereotypy	0.0	0.0	0.0	-0.2	0.2	-0.1
Conditioned locomotion	0.3	0.3	0.5	0.7	-0.7	-0.1
Cocaine response after cond. corrected	2.4	2.7	4.1	-2.0	2.0	-0.1
Cocaine response after cond. not corrected	2.6	2.8	3.8	-1.9	1.9	1.0
Cocaine response before conditioning	1.2	1.4	3.8	0.4	-0.4	1.9
Saline control response	0.4	0.5	0.7	0.8	-0.8	0.2
Bone: connectivity density	0.4	0.6	0.7	0.8	-0.8	-0.6
Bone: cortical apparent density	0.8	1.1	1.6	-1.3	1.2	0.5
Bone: cortical area	0.2	0.3	0.4	0.4	-0.4	0.7
Bone: cortical porosity	0.2	0.2	0.5	-0.2	0.2	-0.7
Bone: cortical porosity	0.2	0.2	0.2	-0.4	0.5	-0.4
Bone: cortical thickness	0.6	1.0	1.1	1.0	-1.1	-0.9
Bone: cortical thickness	0.1	0.1	0.2	-0.0	0.0	0.5
Bone: cortical tissue density	1.0	1.3	1.8	-1.3	1.3	0.6
Condit. Reinf. active minus inactive responses	0.4	0.5	0.7	-0.9	0.8	0.3
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.9	0.3	-0.3	-1.0
Condit. Reinf. active responses	1.3	1.6	1.9	-1.4	1.4	1.0
Condit. Reinf. inactive responses	2.0	2.4	3.7	-1.3	1.3	1.9
Incentive salience index mean	0.4	0.5	0.6	-0.7	0.7	0.8
Condit. Reinf. lever presses	0.2	0.3	0.8	-0.1	0.1	0.9
Condit. Reinf. active minus inactive responses	1.5	1.8	4.6	-0.7	0.7	2.2
Condit. Reinf. active-inactive response ratio	2.9	3.1	5.6	-1.4	1.3	2.4
Condit. Reinf. active responses	0.8	1.1	3.1	0.2	-0.2	1.8
Condit. Reinf. inactive responses	1.1	1.3	1.9	1.4	-1.4	-0.3
Condit. Reinf. lever presses	0.3	0.4	0.6	0.8	-0.8	-0.2
Condit. Reinf. lever reinforcers received	0.9	1.2	3.7	0.1	-0.1	1.9
Conditioned reinforcement - actives	3.4	3.4	4.6	-2.1	2.1	1.1
Conditioned reinforcement - inactives	2.8	3.2	6.9	-1.2	1.1	2.6
Conditioned locomotion	4.0	4.8	6.1	-2.5	2.4	1.5
Patch foraging indifference point 0 sec	2.5	4.1	5.3	2.3	-2.3	-1.3
Patch foraging indifference point AUC	0.2	0.3	0.7	0.2	-0.2	-0.9
Delay disc. indifference point, 0s delay	6.0	6.6	9.2	3.0	-3.0	-1.2
Delay disc. indifference point, 16s delay	1.5	1.5	2.2	-1.5	1.5	-0.2
Delay disc. indifference point, 2s delay	1.1	1.2	1.5	1.2	-1.2	-0.8
Delay disc. indifference point, 24s delay	0.5	0.5	0.7	-0.8	0.8	-0.3
Delay disc. indifference point, 4s delay	0.0	0.0	0.0	0.2	-0.2	0.0
Delay disc. indifference point, 8s delay	2.1	2.2	2.9	1.6	-1.7	-1.0
Indifference point function ln k	1.7	2.4	7.3	-0.1	0.1	2.7
Indifference point function log k	1.7	2.4	7.3	-0.1	0.1	2.7
Patch foraging total patch changes 0 sec	2.4	3.9	5.2	2.2	-2.3	-1.3
Patch foraging total patch changes 12 sec	0.5	0.7	1.5	0.6	-0.6	-1.2
Patch foraging total patch changes 18 sec	1.4	1.8	2.1	1.3	-1.3	-1.4
Patch foraging total patch changes 24 sec	0.6	0.7	1.1	-1.0	1.0	-0.2
Patch foraging total patch changes 6 sec	0.3	0.4	1.1	0.3	-0.3	-1.1
Patch foraging time to switch 0 sec	3.4	5.3	7.5	-2.7	2.7	-1.1
Patch foraging water rate 0 sec	1.0	1.6	2.3	1.5	-1.5	0.4
Patch foraging water rate 12 sec	2.0	3.0	4.2	2.0	-2.0	1.0
Patch foraging water rate 18 sec	0.7	0.9	1.2	1.0	-1.1	0.7
Patch foraging water rate 24 sec	0.4	0.5	0.6	0.7	-0.7	0.7
Patch foraging water rate 6 sec	3.0	4.4	9.2	-1.4	1.4	3.0
Seeking ratio, delayed vs. immediate footshock	6.5	7.5	10.5	3.2	-3.2	-1.3
Distance traveled before self-admin	3.2	3.4	5.0	2.2	-2.2	0.5
Distance traveled after self-admin	10.0	11.2	16.0	4.0	-4.0	-1.3
Extensor digitorum longus weight	0.0	0.1	0.2	-0.0	0.0	0.5
Bone: elastic displacement	1.1	1.3	1.6	1.2	-1.3	-0.9
Bone: elastic work	1.2	1.6	2.4	1.5	-1.5	-0.1
Bone: endosteal estimation	1.2	2.7	5.4	-1.1	1.2	2.3
Bone: endosteal perimeter	0.7	1.5	3.7	-0.6	0.6	1.9
Epididymis fat weight	0.3	0.7	1.1	-1.0	1.0	-0.4
Delta time in closed arm before/after self-admin	0.2	0.2	0.3	0.4	-0.4	-0.5
Delta time in open arm before/after self-admin	0.3	0.3	0.9	0.2	-0.3	0.9
Diff in mean of infusions in LGA sessions	3.7	4.0	5.9	2.4	-2.4	-0.7
Delay discount exponential model param	2.0	2.1	2.5	-1.5	1.6	1.2
Extinction: sum of active levers before priming	4.4	4.4	6.1	2.5	-2.5	-1.0
Active lever presses in extinction session 6	2.5	2.5	3.7	-1.9	1.9	0.3
Bone: final force	0.8	1.3	2.7	-0.8	0.8	1.6
Bone: final moment	0.8	1.2	3.0	-0.6	0.6	1.7
Food consumed during 24 hour testing period	0.6	0.7	1.7	-0.4	0.4	1.3
Glucose	1.3	2.0	2.3	1.5	-1.5	-1.2
Heart weight	0.6	0.8	1.7	0.6	-0.7	1.3
Delay discount hyperbolic model param	1.8	1.9	2.4	-1.5	1.5	1.1
Intermittent access intake day 1-15 change	1.2	1.2	2.5	-0.7	0.7	1.6
Intermittent access intake escalation	2.1	2.0	2.8	-1.3	1.3	1.7
Intermittent access intake escalation 2	0.7	0.7	1.6	-0.6	0.5	1.3
Intermitt. access day 1 inactive lever presses	11.6	12.5	14.9	-3.9	3.8	2.9
Intermitt. access day 15 inactive lever presses	11.4	12.5	14.9	-3.9	3.8	2.8
Intermitt. access escalation Index	0.9	0.8	1.0	0.8	-0.8	-1.0
Intermittent access day 1 total infusions	0.6	0.7	0.8	-0.9	0.9	0.8
Intermittent access day 15 total infusions	3.7	4.2	4.4	-2.1	2.0	2.0
Intermittent access terminal intake (last 3 days)	3.5	3.8	4.2	-2.0	2.0	1.8
Intermittent access total infusions	3.3	3.7	4.1	-2.0	2.0	1.8
Intermittent access day 1 locomotion	0.9	1.0	1.3	-0.9	0.9	1.1
Intermittent access day 15 total locomotion	0.9	0.9	1.9	-0.7	0.6	1.4
Intermittent access total locomotion	2.5	2.8	3.4	-1.6	1.6	1.8
Intermittent access standard deviation	3.8	4.0	5.7	-2.4	2.3	1.0
Left kidney weight	1.5	4.3	9.6	-1.3	1.3	3.1
Right kidney weight	1.5	4.3	8.2	-1.6	1.5	2.9
Cocaine induced anxiety	0.5	0.6	1.8	0.1	-0.2	1.3
Post-drug Anxiety	2.6	2.8	3.8	-1.9	1.9	1.0
Baseline Anxiety	3.0	3.1	4.8	-2.1	2.2	-0.2
Tail length	0.5	1.4	1.5	1.1	-1.2	1.1
Length with tail	1.3	4.6	8.1	-1.7	1.7	2.9
Length without tail	2.3	5.1	5.8	-2.4	2.4	1.9
Times rat made contact with spout	0.7	0.8	0.9	1.0	-0.9	-0.8
Lifetime Intake	1.4	1.6	1.8	-1.3	1.3	1.2
Liver weight, left	2.3	3.7	5.4	-2.3	2.3	0.6
Liver weight, right	0.6	1.0	1.4	-1.2	1.2	0.2
Locomotor activity	0.4	0.7	0.8	0.8	-0.8	-0.9
Locomotor testing distance	0.1	0.2	0.2	0.4	-0.3	-0.5
Locomotor testing rearing	0.0	0.0	0.0	0.2	-0.2	0.2
Locomotion in novel chamber	2.0	2.4	3.1	1.4	-1.4	-1.8
Locomotion in novel chamber post-restriction	1.7	2.0	2.2	1.5	-1.5	-1.3
Fecal boli incidents, locomotor time 1	0.3	0.3	0.4	0.6	-0.7	0.2
Change in fecal boli incidents, locomotor task	4.0	3.8	4.7	1.8	-1.8	-2.2
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	-0.4	0.4	-0.2
Bouts of movement, locomotor time 1	4.0	4.4	6.5	2.5	-2.6	-0.4
Total resting periods, locomotor time 1	2.3	2.5	3.6	1.9	-1.9	-0.6
Rest time, locomotor task time 1	0.9	1.0	1.6	-0.8	0.8	1.3
Distance moved, locomotor task time 1	0.4	0.5	0.7	0.6	-0.6	-0.9
Vertical activity count, locomotor time 1	6.7	7.0	8.5	2.9	-2.9	-2.0
Time >=10cm from walls, locomotor time 2	0.3	0.4	0.6	-0.4	0.5	-0.8
Bouts of movement, locomotor time 2	0.1	0.1	0.1	0.3	-0.3	-0.3
Total resting periods, locomotor time 2	0.4	0.4	0.6	0.8	-0.7	-0.4
Rest time, locomotor task time 2	2.1	2.4	3.4	1.8	-1.8	-0.8
Distance moved, locomotor task time 2	0.0	0.0	0.0	0.0	-0.0	-0.2
Vertical activity count, locomotor time 2	1.8	2.0	2.6	1.6	-1.6	-0.9
Light reinforcement 1	1.3	2.3	3.3	1.8	-1.8	-0.6
Light reinforcement 2	0.2	0.3	0.8	0.3	-0.3	-0.9
Bone: marrow area	1.2	2.6	5.4	-1.1	1.1	2.3
Bone: maximum diameter	0.2	0.4	1.3	0.0	-0.0	1.1
Bone: maximum force	0.7	1.2	2.8	-0.6	0.6	1.7
Bone: maximum moment	0.7	1.1	3.1	-0.4	0.4	1.8
Mean time between licks in bursts	1.7	2.4	2.6	1.6	-1.6	-1.5
Mean num. licks in bursts	1.0	1.2	1.4	1.2	-1.1	-0.9
Cd content in liver	0.8	0.9	1.4	1.2	-1.2	0.2
Co content in liver	0.7	0.8	1.0	-0.8	0.8	1.0
Cu content in liver	1.6	2.0	2.3	-1.5	1.5	1.2
Fe content in liver	0.4	0.5	0.5	-0.7	0.7	0.6
K content in liver	0.0	0.0	0.0	0.1	-0.1	0.1
Mg content in liver	0.1	0.1	0.1	-0.1	0.1	-0.4
Mn content in liver	0.1	0.1	0.4	0.1	-0.1	-0.6
Na content in liver	0.7	0.8	1.9	0.5	-0.5	-1.4
Rb content in liver	0.2	0.2	0.3	-0.5	0.5	0.3
Se content in liver	1.1	1.4	2.9	0.8	-0.8	-1.7
Sr content in liver	14.5	13.3	14.8	3.8	-3.8	-3.2
Zn content in liver	1.3	1.4	2.1	-1.4	1.4	0.2
Bone: minimum diameter	0.7	1.3	3.8	-0.1	0.2	2.0
Time in familiar zone, hab. session 1	1.6	1.5	1.9	1.4	-1.4	0.9
Time in novel zone, hab. session 1	2.3	2.2	3.3	-1.8	1.8	-0.3
Total zone transitions, hab. session 1	0.2	0.3	0.9	0.3	-0.2	0.9
Total locomotion distance, hab. session 1	1.0	1.4	2.2	1.5	-1.5	-0.0
Locomotion velocity, hab. session 1	0.6	0.8	1.2	1.1	-1.1	0.0
Time in familiar zone, hab. session 2	2.6	2.6	3.0	-1.6	1.6	1.7
Time in novel zone, hab. session 2	0.4	0.4	1.1	0.3	-0.3	-1.1
Total zone transitions, hab. session 2	0.5	0.7	1.3	0.6	-0.6	1.1
Total locomotion distance, hab. session 2	1.9	2.5	3.6	1.9	-1.9	-0.5
Locomotion velocity, hab. session 2	2.5	3.3	4.8	2.2	-2.2	-0.7
Novel to familiar place preference ratio	1.0	1.1	1.4	1.2	-1.2	-0.6
Novelty place preference	0.5	0.5	0.7	0.8	-0.8	-0.2
Time in novel zone, NPP test	0.3	0.3	0.4	0.6	-0.6	-0.1
Total zone transitions, NPP test	0.2	0.3	0.5	0.7	-0.7	0.1
Total locomotion distance, NPP test	0.9	1.2	1.7	1.3	-1.3	-0.3
Locomotion velocity, NPP test	1.1	1.6	2.3	1.5	-1.5	-0.3
Intraocular pressure	0.3	0.5	0.6	-0.8	0.8	0.5
Delta distance traveled before/after self-admin	2.8	3.0	3.4	1.8	-1.8	-1.5
Delta ambulatory time before/after self-admin	2.7	3.0	3.4	1.8	-1.8	-1.4
Parametrial fat weight	2.4	4.7	9.9	1.5	-1.5	-3.1
Pavlov. Cond. lever latency	0.1	0.1	0.1	-0.4	0.4	0.2
Pavlov. Cond. magazine entry latency	0.6	0.8	1.4	0.8	-0.7	-1.2
Pavlov. Cond. change in total contacts	0.4	0.4	0.5	0.7	-0.7	-0.5
Pavlov. Cond. index score	0.6	0.7	0.7	0.9	-0.8	-0.8
Pavlov. Cond. latency score	0.6	0.7	0.8	0.9	-0.9	-0.8
Pavlov. Cond. lever contacts	0.0	0.0	0.0	-0.0	0.0	-0.1
Pavlov. Cond. magazine entry number	0.8	1.0	1.1	-1.0	1.0	1.0
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.3	0.6	-0.6	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	0.6	0.7	-0.7	-0.8
Pavlov. Cond. response bias	0.1	0.1	0.2	0.0	-0.0	-0.4
Pavlov. Cond. lever latency	5.3	7.2	8.5	-2.9	2.9	2.2
Pavlov. Cond. magazine entry latency	2.2	2.6	3.0	1.5	-1.5	-1.7
Pavlov. Cond. change in total contacts	2.0	2.8	4.0	2.0	-2.0	-0.6
Pavlov. Cond. index score	2.6	3.3	3.9	2.0	-2.0	-1.5
Pavlov. Cond. latency score	3.1	3.8	4.3	2.1	-2.1	-1.7
Pavlov. Cond. lever contacts	2.6	3.6	4.4	2.1	-2.1	-1.4
Pavlov. Cond. magazine entry number	1.3	1.5	1.6	-1.2	1.2	1.3
Pavlov. Cond. intertrial magazine entries	3.3	4.3	6.6	-1.8	1.8	2.6
Pavlov. Cond. lever-magazine prob. diff.	2.3	2.9	3.5	1.9	-1.9	-1.3
Pavlov. Cond. response bias	1.3	1.8	2.5	1.6	-1.5	-0.8
Time in closed arm before self-admin	2.0	2.3	2.5	-1.6	1.5	1.4
Time in closed arm after self-admin	1.0	1.0	1.4	-1.2	1.2	0.5
Time in open arm before self-admin	2.6	2.8	3.0	1.7	-1.7	-1.6
Time in open arm after self-admin	1.5	1.6	2.2	1.5	-1.4	-0.8
Bone: periosteal estimation	0.6	1.3	3.4	-0.4	0.5	1.9
Bone: periosteal perimeter	0.6	0.9	2.5	-0.3	0.4	1.6
Bone: post-yield work	2.2	3.0	3.1	-1.7	1.8	1.7
Progressive ratio test 1 active lever presses	0.3	0.3	0.5	0.4	-0.4	0.7
Progressive ratio test 1 breakpoint	0.2	0.3	0.5	0.4	-0.4	0.7
Progressive ratio test 1 inactive lever presses	3.3	3.6	5.5	-1.6	1.6	2.4
Progressive ratio test 2 active lever presses	1.7	1.8	2.4	-1.3	1.2	1.5
Progressive ratio test 2 breakpoint	2.4	2.7	3.2	-1.6	1.5	1.8
Progressive ratio test 2 inactive lever presses	3.3	3.9	5.8	-1.7	1.7	2.4
Incentive Sensitization - Responses	8.5	8.6	9.0	-3.0	2.9	2.9
Incentive Sensitization - Breakpoint	7.8	8.0	8.8	-3.0	2.9	2.6
Sum of active levers in priming session hrs 5-6	1.6	1.6	2.4	1.5	-1.6	-0.3
Progressive ratio	3.6	4.1	5.3	2.3	-2.3	-1.4
Food seeking constrained by brief footshock	30.2	37.1	52.4	7.2	-7.2	-2.6
Seeking ratio, punishment vs. effort	2.3	2.9	4.3	2.1	-2.1	-0.2
Retroperitoneal fat weight	2.7	8.9	17.3	2.2	-2.2	-4.2
Reaction time number correct	2.7	3.9	5.0	2.2	-2.2	-1.4
Reaction time mean minus median	0.5	0.7	0.9	-1.0	1.0	0.4
Reaction time mean minus median AUC	0.5	0.7	1.0	-1.0	1.0	0.2
Reaction time num false alarms	0.1	0.2	0.3	0.5	-0.5	-0.1
Reaction time num false alarms AUC	1.3	1.8	2.5	1.6	-1.6	-0.8
Reaction time trials correct on left	2.7	3.9	5.0	2.2	-2.2	-1.4
Reaction time trials on left	2.6	3.8	4.8	2.2	-2.2	-1.3
Reaction time mean	4.5	6.3	7.9	-2.8	2.8	1.8
Reaction time mean AUC	3.9	5.2	6.9	-2.6	2.6	1.4
Median of all reaction times	3.5	4.8	5.9	-2.4	2.4	1.6
Reaction time omissions	0.1	0.1	0.1	0.3	-0.3	-0.2
Reaction time false alarm rate	0.0	0.0	0.1	0.2	-0.3	0.0
Reaction time premature initiation rate	0.0	0.0	0.0	-0.2	0.1	0.0
Reaction time premature initiations	0.6	0.9	1.0	1.0	-1.0	-0.8
Std. dev. reaction times	2.2	3.0	3.8	-2.0	1.9	1.2
Reaction time trials completed	2.6	3.8	4.8	2.2	-2.2	-1.3
Reaction time trials AUC	2.4	3.5	4.4	2.1	-2.1	-1.3
Run reversals in cocaine runway, females	1.3	1.2	1.6	-1.3	1.2	0.8
Run reversals in cocaine runway, males	0.5	0.5	0.6	-0.8	0.8	0.4
Latency to leave start box in cocaine runway	0.5	0.5	0.9	-0.6	0.5	1.0
Latency to leave start box in cocaine runway, F	0.1	0.1	0.1	0.1	-0.2	0.4
Latency to leave start box in cocaine runway, M	1.6	1.6	1.6	-1.3	1.3	1.2
Std. dev. time between licks in bursts	0.5	0.6	0.9	0.9	-1.0	0.1
Total sessions with >9 infusions	3.3	3.7	3.8	-1.9	1.9	1.9
Short access day 1 total inactive lever presses	5.4	6.0	7.8	-2.8	2.8	1.6
Short access day 10 total inactive lever presses	4.0	4.4	5.5	-2.3	2.3	1.5
Short access day 1 total infusions	0.0	0.0	0.0	0.1	-0.1	0.1
Short access day 10 total infusions	0.8	0.9	1.3	-1.2	1.2	0.4
Short access total infusions	0.5	0.5	0.6	0.7	-0.7	-0.7
Short access day 1 locomotion	1.8	2.0	2.3	-1.5	1.5	1.2
Short access day 10 total locomotion	0.7	0.7	1.8	-0.5	0.5	1.3
Short access total locomotion	0.7	0.7	1.1	1.0	-1.1	-0.1
One hour access (0.3 mA shock)	7.0	8.1	8.3	-2.9	2.8	2.9
Compulsive drug intake	1.2	1.2	1.9	-0.9	0.9	1.4
One hour access (shock baseline)	7.4	8.6	11.2	-3.3	3.3	1.9
Social response proportion	4.1	4.4	5.2	-2.3	2.2	1.7
Social responses	5.4	7.0	7.0	-2.6	2.6	2.6
Social time	1.1	1.5	2.7	0.9	-0.9	1.6
Soleus weight	0.2	0.5	0.8	0.9	-0.9	-0.2
Bone: stiffness	2.0	3.2	4.3	-1.6	1.6	2.1
Tibialis anterior weight	1.8	6.2	6.8	2.4	-2.4	-2.6
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.4	-0.1	0.1	0.6
Time to tail flick, vehicle, after self-admin	5.1	5.5	6.6	-2.6	2.5	1.9
Time to tail flick, test, before self-admin	9.6	9.3	13.9	3.7	-3.7	-0.5
Time to tail flick, test, after self-admin	0.1	0.1	0.1	-0.3	0.3	0.1
Delta time to tail flick, vehicle, before/after SA	2.4	2.3	3.3	-1.8	1.8	0.8
Delta time to tail flick, test, before/after SA	6.2	5.6	8.2	-2.9	2.9	0.7
Tibia length	1.2	3.2	7.6	-1.0	1.0	2.8
Ambulatory time before self-admin	1.9	2.0	2.9	1.7	-1.7	0.4
Ambulatory time after self-admin	7.8	8.6	12.7	3.6	-3.6	-0.6
Bone: tissue strength	3.3	3.2	4.7	2.1	-2.2	-0.6
Total heroin consumption	1.8	2.1	2.2	1.5	-1.5	-1.4
Bone: trabecular number	1.1	1.7	2.2	1.5	-1.4	-0.9
Bone: trabecular spacing	0.1	0.2	0.2	0.4	-0.4	-0.5
Bone: trabecular thickness	0.2	0.2	0.3	-0.6	0.6	0.2
Bone: trabecular tissue density	2.0	2.8	4.1	-2.0	2.0	-0.3
Water consumed over 24 hours	0.3	0.4	0.9	0.3	-0.3	0.9
Number of responses in last shaping day	3.5	3.6	4.6	-2.2	2.1	1.3