Hub : Genes

Vom1r47

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Vom1r47 0.14 0.09 3.3e-06 0.01 0.03 0.02 0.02 2.3e-03 2.5e-05 1.5e-04 2.9e-04
2 RMTg isoform ratio XM_063270359.1 0.29 0.18 6.8e-04 0.14 0.12 0.15 0.12 2.0e-04 4.9e-04 1.1e-04 5.3e-04
3 Brain gene expression Vom1r47 0.08 0.06 1.9e-08 0.08 0.08 0.08 0.08 1.2e-07 5.0e-08 6.0e-08 5.6e-08
4 RMTg alternative TSS XM_063270359.1 0.3 0.18 1.9e-03 0.04 0.09 0.11 0.1 2.6e-02 1.8e-03 8.0e-04 1.3e-03
5 RMTg isoform ratio XM_063270370.1 0.08 0.07 9.8e-03 0.08 0.05 0.03 0.05 4.3e-03 1.6e-02 6.7e-02 1.5e-02
6 NAcc intron excision ratio chr1_81546723_81555570 0.02 0.02 7.1e-03 0.01 0.01 0.01 0.01 4.0e-03 5.3e-03 1.2e-02 7.3e-03
7 RMTg isoform ratio XM_063270367.1 0.45 0.2 6.3e-04 0.14 0.14 0.14 0.14 1.4e-04 1.2e-04 1.3e-04 1.4e-04
8 RMTg alternative TSS XM_063270367.1 0.28 0.18 5.0e-03 0.03 0.07 0.09 0.08 5.1e-02 7.9e-03 1.9e-03 4.7e-03
9 Brain isoform ratio XM_063270370.1 0.03 0.02 5.3e-04 0.03 0.03 0.03 0.03 1.3e-03 6.3e-04 1.7e-03 1.8e-03
10 pVTA intron excision ratio chr1_81486834_81507518 0.04 0.03 9.3e-03 0 0.01 -0 0 2.1e-01 3.3e-02 3.8e-01 2.9e-01
11 RMTg gene expression Vom1r47 0.45 0.2 5.0e-05 0.04 0.16 0.12 0.16 3.3e-02 4.8e-05 5.0e-04 3.9e-05
12 pVTA alternative TSS XM_063270359.1 0.09 0.07 5.1e-03 0.01 0.02 0.02 0.02 4.9e-02 7.0e-03 4.6e-03 1.9e-02
13 pVTA gene expression Vom1r47 0.48 0.18 5.6e-15 0.17 0.18 0.18 0.18 1.0e-13 2.2e-14 2.0e-14 3.0e-14
14 pVTA alternative TSS XM_063270367.1 0.17 0.11 1.1e-04 0.05 0.05 0.05 0.04 1.2e-04 6.4e-05 4.8e-05 1.5e-04
15 pVTA alternative TSS XM_063270359.1 0.17 0.11 1.1e-04 0.05 0.05 0.05 0.05 1.3e-04 6.6e-05 4.6e-05 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.00.10.20.20.2-0.20.2-0.40.3-0.2-0.10.30.3-0.1-0.2-0.10.2-0.2
Area under the delay curve0.20.41.01.0-0.90.8-0.60.7-0.5-0.80.6-0.6-0.50.20.3-0.0-0.10.2
BMI with tail0.41.22.40.7-1.31.5-0.81.5-1.6-0.50.7-1.5-1.5-0.31.00.7-0.91.0
BMI without tail0.10.30.9-0.30.0-0.10.50.1-0.10.4-0.60.00.0-1.00.70.8-0.80.8
Body weight1.04.38.7-2.32.5-2.12.9-1.71.72.4-2.91.81.6-2.51.01.7-1.31.3
Weight adjusted by age0.20.61.20.40.4-0.80.2-1.01.1-0.4-0.11.01.10.5-1.0-0.70.9-0.9
Bone surface1.73.26.7-1.72.6-2.42.3-2.42.11.6-2.22.22.1-1.1-0.40.30.1-0.2
Bone volume1.52.96.1-1.72.5-2.22.2-2.21.81.6-2.12.01.9-1.2-0.20.5-0.00.0
Breakpoint value in progressive ratio session0.10.20.60.3-0.10.7-0.20.5-0.8-0.30.2-0.7-0.70.10.30.1-0.20.2
Number of licking bursts0.00.00.1-0.40.0-0.0-0.00.1-0.20.30.0-0.1-0.10.3-0.10.00.1-0.1
Context. condit. distance diff. score0.30.30.90.9-0.60.3-0.60.1-0.0-0.90.7-0.00.00.6-0.6-0.60.5-0.5
Locomotion velocity, session 13.13.57.41.6-0.8-0.6-1.6-0.81.0-1.91.81.11.32.6-2.7-2.72.7-2.7
Locomotion distance, session 12.43.05.90.31.1-2.00.4-2.32.2-0.6-0.12.32.41.1-2.3-1.82.0-2.1
Locomotion velocity, session 21.11.33.11.1-0.7-0.1-1.2-0.20.4-1.31.40.40.51.7-1.5-1.81.6-1.6
Locomotion distance, session 21.31.83.5-0.51.2-1.80.7-1.81.80.2-0.51.91.90.6-1.4-1.11.3-1.4
Locomotion velocity, session 30.10.10.40.0-0.4-0.0-0.50.1-0.0-0.20.50.00.00.6-0.5-0.50.4-0.5
Locomotion distance, session 30.40.51.10.7-0.1-0.4-0.2-0.60.8-0.70.30.70.80.8-1.0-0.90.9-0.9
Stereotopy head waving bouts, day 30.10.10.2-0.4-0.10.2-0.10.4-0.50.40.0-0.3-0.4-0.20.20.3-0.30.3
Stereotopy head waving duration, day 30.10.10.3-0.4-0.10.1-0.10.3-0.50.40.0-0.3-0.3-0.30.20.3-0.30.3
Locomotion velocity, session 70.30.41.1-0.10.2-0.6-0.2-0.60.3-0.10.30.60.60.7-1.0-0.80.9-0.9
Locomotion distance, session 70.40.51.20.5-0.2-0.3-0.6-0.40.3-0.60.70.50.51.0-1.0-1.11.1-1.1
Stereotopy head waving bouts, day 70.20.30.7-0.80.5-0.30.6-0.10.20.8-0.70.10.0-0.60.30.5-0.50.4
Stereotopy head waving duration, day 70.20.20.5-0.70.6-0.40.7-0.30.20.7-0.70.20.2-0.60.30.5-0.40.4
Locomotion velocity, session 80.91.02.31.0-0.3-0.2-0.8-0.50.5-1.21.00.50.61.4-1.5-1.51.4-1.4
Locomotion distance, session 80.50.81.70.7-0.0-0.5-0.4-0.70.8-0.80.50.80.91.0-1.3-1.21.2-1.2
Degree of sensitization distance0.00.00.0-0.10.1-0.1-0.1-0.0-0.00.10.10.00.00.1-0.1-0.20.1-0.1
Degree of sensitization stereotypy0.10.10.2-0.30.10.10.30.1-0.00.4-0.4-0.2-0.2-0.50.40.5-0.50.5
Conditioned locomotion0.50.61.20.9-0.3-0.1-0.6-0.30.4-0.90.70.40.41.0-1.1-1.11.0-1.0
Cocaine response after cond. corrected1.11.73.5-1.2-0.51.1-0.21.7-1.91.10.1-1.6-1.8-0.71.71.3-1.51.4
Cocaine response after cond. not corrected0.60.92.7-1.70.8-0.31.00.1-0.31.6-1.0-0.1-0.3-1.11.11.2-1.11.0
Cocaine response before conditioning3.54.29.6-0.82.5-2.72.2-3.13.10.8-2.12.92.9-0.6-1.2-0.30.9-0.9
Saline control response1.01.43.41.1-0.1-0.5-0.7-0.90.8-1.30.80.80.91.5-1.8-1.61.7-1.7
Bone: connectivity density0.10.20.50.7-0.50.4-0.50.2-0.2-0.70.6-0.3-0.20.4-0.2-0.40.3-0.2
Bone: cortical apparent density0.30.41.20.1-0.2-0.3-0.6-0.20.4-0.40.70.40.41.0-0.7-1.11.0-1.0
Bone: cortical area0.60.92.3-0.21.3-1.11.3-1.51.10.3-1.21.21.3-0.7-0.30.20.1-0.1
Bone: cortical porosity0.20.30.80.3-0.40.8-0.40.7-0.9-0.30.3-0.8-0.80.00.30.3-0.30.3
Bone: cortical porosity0.20.30.6-0.40.10.40.20.4-0.70.4-0.3-0.6-0.6-0.50.60.7-0.70.6
Bone: cortical thickness0.30.51.21.1-0.70.5-0.80.1-0.4-1.10.9-0.2-0.10.8-0.7-0.70.6-0.6
Bone: cortical thickness0.20.30.70.10.1-0.5-0.3-0.50.5-0.30.30.60.60.6-0.7-0.80.8-0.8
Bone: cortical tissue density0.20.41.10.0-0.2-0.3-0.6-0.10.4-0.30.70.40.40.9-0.7-1.00.9-0.9
Condit. Reinf. active minus inactive responses0.00.10.3-0.50.10.1-0.10.2-0.50.30.1-0.2-0.3-0.00.00.0-0.10.1
Condit. Reinf. active-inactive response ratio0.60.71.90.5-0.81.1-0.81.0-1.4-0.40.8-1.2-1.20.10.40.1-0.40.4
Condit. Reinf. active responses0.20.30.9-1.00.9-0.70.6-0.50.30.8-0.60.40.3-0.4-0.00.1-0.10.1
Condit. Reinf. inactive responses1.51.94.0-1.21.8-1.91.6-1.72.01.0-1.41.81.8-0.5-0.6-0.10.4-0.4
Incentive salience index mean0.10.20.5-0.50.7-0.60.4-0.60.20.4-0.40.50.4-0.2-0.2-0.10.1-0.1
Condit. Reinf. lever presses0.40.61.6-0.41.2-1.00.9-1.31.00.3-0.81.11.1-0.3-0.4-0.30.4-0.4
Condit. Reinf. active minus inactive responses1.62.55.6-0.81.9-2.11.7-2.22.40.7-1.52.22.2-0.4-0.9-0.30.7-0.7
Condit. Reinf. active-inactive response ratio1.93.15.8-1.62.4-2.32.2-2.22.31.5-2.12.22.1-1.2-0.30.30.1-0.2
Condit. Reinf. active responses1.72.45.9-0.21.6-2.01.3-2.32.40.1-1.12.32.30.1-1.4-0.81.2-1.2
Condit. Reinf. inactive responses0.20.30.91.0-0.2-0.1-0.2-0.40.5-0.80.20.40.50.5-0.8-0.50.6-0.6
Condit. Reinf. lever presses0.40.61.9-0.00.6-0.11.1-0.40.40.3-1.20.10.2-1.40.81.2-1.01.1
Condit. Reinf. lever reinforcers received2.12.97.1-0.31.8-2.21.5-2.62.70.3-1.32.52.5-0.0-1.5-0.71.1-1.1
Conditioned reinforcement - actives0.20.72.3-1.5-0.0-0.60.60.20.11.4-0.70.20.1-1.01.00.9-1.01.0
Conditioned reinforcement - inactives0.71.84.0-1.11.4-2.01.4-1.81.91.0-1.32.01.9-0.6-0.4-0.10.3-0.3
Conditioned locomotion0.20.30.8-0.90.4-0.30.50.10.00.8-0.50.0-0.0-0.60.60.6-0.50.5
Patch foraging indifference point 0 sec0.51.34.12.0-1.20.8-1.30.3-0.1-1.91.4-0.3-0.11.2-1.1-1.21.1-1.0
Patch foraging indifference point AUC0.20.51.30.0-0.81.0-0.61.1-1.1-0.00.5-1.1-1.1-0.00.60.4-0.50.5
Delay disc. indifference point, 0s delay1.01.23.61.9-0.50.1-0.8-0.70.6-1.70.80.50.71.1-1.3-1.31.3-1.2
Delay disc. indifference point, 16s delay1.11.52.9-1.0-0.10.90.31.3-1.41.1-0.5-1.4-1.5-1.11.71.5-1.61.6
Delay disc. indifference point, 2s delay0.50.61.51.2-1.20.6-1.10.7-0.3-1.11.1-0.3-0.20.8-0.2-0.60.4-0.3
Delay disc. indifference point, 24s delay0.30.61.4-0.30.00.90.00.9-1.10.4-0.1-1.1-1.2-0.40.90.7-0.80.7
Delay disc. indifference point, 4s delay0.10.10.1-0.1-0.1-0.20.20.10.20.2-0.20.20.2-0.30.30.2-0.30.3
Delay disc. indifference point, 8s delay0.20.31.41.2-0.90.6-0.70.4-0.1-1.00.7-0.3-0.20.4-0.1-0.30.2-0.1
Indifference point function ln k1.54.711.3-0.62.1-3.01.8-3.03.40.5-1.63.33.3-0.1-1.7-1.01.4-1.4
Indifference point function log k1.54.711.3-0.62.1-3.01.8-3.03.40.5-1.63.33.3-0.1-1.7-1.01.4-1.4
Patch foraging total patch changes 0 sec0.41.24.02.0-1.10.8-1.30.2-0.1-1.91.3-0.2-0.11.2-1.1-1.21.0-1.0
Patch foraging total patch changes 12 sec0.30.40.90.3-0.70.9-0.50.9-0.9-0.20.4-1.0-1.0-0.20.50.4-0.50.5
Patch foraging total patch changes 18 sec0.30.81.51.2-1.21.1-1.20.9-0.6-1.11.2-0.8-0.80.9-0.4-0.50.3-0.3
Patch foraging total patch changes 24 sec0.20.61.1-1.00.40.20.50.5-0.51.0-0.6-0.5-0.6-0.91.01.0-0.90.9
Patch foraging total patch changes 6 sec0.50.81.80.8-1.11.4-0.91.2-1.2-0.60.8-1.3-1.30.00.50.3-0.50.5
Patch foraging time to switch 0 sec1.66.110.7-1.8-1.02.1-0.23.2-3.21.8-0.2-3.0-3.2-1.73.32.7-3.13.0
Patch foraging water rate 0 sec0.41.63.01.10.2-0.9-0.2-1.51.5-1.10.31.41.61.0-1.7-1.51.6-1.6
Patch foraging water rate 12 sec0.93.57.21.20.6-1.80.2-2.32.7-1.20.02.52.71.2-2.3-1.92.1-2.1
Patch foraging water rate 18 sec0.71.73.11.00.2-1.0-0.1-1.51.6-1.10.31.51.61.1-1.8-1.51.7-1.6
Patch foraging water rate 24 sec0.91.32.50.50.4-1.1-0.0-1.31.5-0.60.21.41.50.9-1.6-1.31.4-1.4
Patch foraging water rate 6 sec3.65.310.2-2.13.1-3.22.8-3.12.91.9-2.63.02.9-1.2-0.80.20.4-0.4
Seeking ratio, delayed vs. immediate footshock1.21.75.12.3-0.40.1-0.8-0.90.9-2.10.90.60.91.3-1.6-1.51.6-1.5
Distance traveled before self-admin1.83.96.91.81.0-1.40.2-2.62.5-1.70.12.22.51.4-2.6-2.12.5-2.5
Distance traveled after self-admin1.62.99.73.1-0.50.7-1.2-0.80.5-2.81.40.20.51.9-2.0-2.02.1-2.0
Extensor digitorum longus weight0.41.53.6-1.11.2-0.71.7-0.60.61.3-1.80.50.5-1.91.21.5-1.41.4
Bone: elastic displacement0.50.61.31.1-1.10.9-1.00.7-0.5-1.01.0-0.7-0.60.7-0.4-0.40.3-0.2
Bone: elastic work0.20.30.80.70.2-0.40.2-0.80.9-0.5-0.20.70.8-0.0-0.5-0.30.4-0.3
Bone: endosteal estimation1.74.18.2-2.02.8-2.32.9-2.32.12.1-2.82.12.0-2.00.41.2-0.70.6
Bone: endosteal perimeter1.02.44.6-1.32.1-1.92.1-1.91.81.4-2.11.81.7-1.4-0.00.6-0.30.2
Epididymis fat weight0.41.93.6-1.71.40.21.50.1-0.71.8-1.6-0.7-0.9-1.81.61.9-1.61.5
Delta time in closed arm before/after self-admin0.10.10.50.3-0.70.3-0.50.4-0.3-0.30.4-0.2-0.20.20.1-0.10.00.0
Delta time in open arm before/after self-admin0.91.02.4-0.61.5-1.31.1-1.51.30.5-1.01.41.3-0.2-0.7-0.20.5-0.5
Diff in mean of infusions in LGA sessions0.30.61.41.2-0.6-0.1-0.6-0.50.7-1.10.60.50.70.5-0.9-0.90.9-0.8
Delay discount exponential model param0.20.30.7-0.90.8-0.70.5-0.60.40.7-0.50.50.5-0.1-0.3-0.00.2-0.2
Extinction: sum of active levers before priming0.10.20.40.60.20.3-0.3-0.1-0.2-0.60.3-0.1-0.10.5-0.5-0.50.5-0.6
Active lever presses in extinction session 61.51.53.3-1.80.60.20.90.8-0.91.7-1.0-0.8-1.0-1.51.61.5-1.61.5
Bone: final force1.32.24.6-1.02.1-1.91.8-2.21.80.9-1.71.91.9-1.0-0.30.20.2-0.2
Bone: final moment1.72.76.2-0.92.3-2.22.0-2.52.10.8-1.82.22.2-1.0-0.50.00.4-0.4
Food consumed during 24 hour testing period0.50.92.0-0.61.3-1.21.2-1.31.40.6-1.11.21.2-0.7-0.20.10.1-0.1
Glucose1.21.84.02.0-1.91.5-1.81.2-1.1-1.91.8-1.1-1.01.1-0.3-0.80.4-0.4
Heart weight0.91.53.3-1.21.8-1.11.8-1.21.01.3-1.80.90.8-1.50.61.0-0.70.7
Delay discount hyperbolic model param0.30.41.1-1.11.0-0.80.7-0.70.40.9-0.60.60.5-0.2-0.20.10.1-0.2
Intermittent access intake day 1-15 change0.10.81.8-1.21.3-1.11.1-0.90.91.0-1.10.90.8-0.60.00.3-0.10.0
Intermittent access intake escalation0.21.32.9-1.71.7-1.41.5-1.11.01.5-1.51.11.0-0.90.20.5-0.30.2
Intermittent access intake escalation 20.20.40.70.30.6-0.50.2-0.90.8-0.3-0.10.70.70.4-0.7-0.60.7-0.8
Intermitt. access day 1 inactive lever presses0.21.94.7-2.21.9-1.61.8-1.11.12.0-1.81.11.0-1.20.50.8-0.60.5
Intermitt. access day 15 inactive lever presses0.52.96.1-2.52.4-1.82.3-1.31.32.3-2.31.31.1-1.70.71.2-0.80.8
Intermitt. access escalation Index0.10.20.60.4-0.40.7-0.50.6-0.7-0.40.5-0.7-0.70.20.30.0-0.10.1
Intermittent access day 1 total infusions0.20.51.4-1.20.4-0.70.8-0.20.41.1-0.80.50.4-0.90.60.7-0.60.7
Intermittent access day 15 total infusions0.61.44.2-2.11.2-1.21.4-0.50.71.9-1.40.80.6-1.30.91.0-0.90.8
Intermittent access terminal intake (last 3 days)0.61.02.7-1.70.9-1.21.2-0.50.71.5-1.20.80.7-1.00.60.7-0.60.6
Intermittent access total infusions1.11.33.7-1.91.0-1.41.4-0.60.91.8-1.41.00.8-1.20.70.8-0.70.7
Intermittent access day 1 locomotion0.51.02.2-1.51.0-1.31.2-0.80.91.3-1.21.00.9-0.90.50.6-0.40.4
Intermittent access day 15 total locomotion0.31.02.9-0.20.7-1.50.6-1.41.70.1-0.51.61.60.0-0.8-0.60.7-0.7
Intermittent access total locomotion1.82.24.5-1.81.8-2.11.8-1.71.91.6-1.71.91.8-1.00.00.3-0.10.0
Intermittent access standard deviation0.00.20.40.6-0.50.5-0.50.3-0.3-0.60.5-0.3-0.30.4-0.1-0.30.2-0.2
Left kidney weight1.814.626.2-3.65.1-5.05.0-4.84.73.5-4.84.64.4-2.9-0.41.1-0.20.1
Right kidney weight2.416.732.0-4.45.5-4.95.7-4.54.44.4-5.54.34.0-3.80.52.1-1.11.1
Cocaine induced anxiety0.41.12.7-1.11.6-1.31.3-1.31.21.0-1.21.21.1-0.5-0.30.10.1-0.2
Post-drug Anxiety0.91.02.8-1.71.5-0.91.3-0.60.41.5-1.30.50.4-0.90.30.7-0.50.4
Baseline Anxiety0.30.50.90.4-0.90.9-0.71.0-1.0-0.40.7-0.9-0.90.20.40.1-0.30.3
Tail length1.37.012.5-2.43.5-3.53.4-3.33.32.4-3.33.33.2-1.9-0.40.6-0.0-0.0
Length with tail2.310.319.9-3.84.3-3.74.5-3.23.13.8-4.43.12.9-3.20.71.9-1.21.2
Length without tail1.57.716.7-4.13.5-2.33.8-1.61.44.0-3.81.41.1-3.21.82.6-2.12.0
Times rat made contact with spout0.10.10.30.4-0.40.5-0.20.4-0.4-0.20.2-0.5-0.5-0.30.40.3-0.40.4
Lifetime Intake0.81.02.9-1.70.7-1.11.1-0.40.71.6-1.10.80.6-1.10.80.8-0.80.8
Liver weight, left0.91.52.7-1.41.6-1.61.7-1.41.21.4-1.61.41.3-1.10.00.6-0.20.2
Liver weight, right0.00.00.20.4-0.2-0.0-0.0-0.10.1-0.30.00.20.2-0.1-0.1-0.10.1-0.0
Locomotor activity0.20.30.70.00.00.60.30.3-0.50.2-0.4-0.7-0.7-0.60.80.8-0.70.7
Locomotor testing distance0.30.71.7-0.90.60.20.90.2-0.31.0-1.0-0.4-0.5-1.01.21.3-1.11.1
Locomotor testing rearing0.20.61.6-0.71.0-0.41.2-0.60.40.9-1.30.30.3-1.00.61.0-0.70.7
Locomotion in novel chamber0.40.61.20.7-1.11.0-1.01.0-1.0-0.70.9-1.0-0.90.50.2-0.1-0.10.1
Locomotion in novel chamber post-restriction0.30.81.90.7-1.41.1-0.91.4-0.9-0.60.8-1.0-1.0-0.00.70.2-0.60.6
Fecal boli incidents, locomotor time 10.10.10.50.10.3-0.50.4-0.50.70.0-0.40.60.6-0.2-0.1-0.00.1-0.0
Change in fecal boli incidents, locomotor task1.81.93.81.6-1.91.7-1.91.6-1.5-1.51.8-1.5-1.41.2-0.0-0.60.3-0.2
Time >=10cm from walls, locomotor time 10.10.10.2-0.4-0.00.2-0.00.4-0.40.4-0.0-0.3-0.4-0.10.30.3-0.30.3
Bouts of movement, locomotor time 11.62.13.91.8-0.1-0.5-0.6-1.41.3-1.80.81.11.31.4-2.0-1.81.9-1.9
Total resting periods, locomotor time 11.01.12.21.5-0.4-0.0-0.8-0.70.6-1.50.90.50.71.3-1.4-1.41.4-1.4
Rest time, locomotor task time 10.40.71.2-0.91.1-1.11.1-1.01.00.8-1.01.00.9-0.5-0.10.20.0-0.0
Distance moved, locomotor task time 10.30.71.41.0-1.11.2-1.11.0-1.1-0.91.0-1.1-1.00.60.0-0.20.0-0.0
Vertical activity count, locomotor time 10.43.08.32.9-2.31.7-2.31.1-0.9-2.62.2-1.1-0.81.7-0.9-1.30.9-0.8
Time >=10cm from walls, locomotor time 20.20.51.6-0.2-0.60.9-0.61.1-1.20.00.5-1.1-1.10.20.50.2-0.40.3
Bouts of movement, locomotor time 20.00.00.00.00.1-0.00.1-0.10.0-0.0-0.10.00.0-0.10.00.1-0.00.0
Total resting periods, locomotor time 20.00.00.00.2-0.0-0.1-0.0-0.20.2-0.20.00.20.20.1-0.1-0.20.2-0.2
Rest time, locomotor task time 20.10.20.80.9-0.3-0.1-0.3-0.40.5-0.80.30.40.50.4-0.6-0.60.6-0.5
Distance moved, locomotor task time 20.10.10.20.3-0.20.4-0.30.3-0.4-0.30.3-0.4-0.40.1-0.0-0.0-0.0-0.0
Vertical activity count, locomotor time 20.10.31.21.1-0.90.5-0.70.4-0.1-0.90.6-0.2-0.10.4-0.2-0.30.1-0.1
Light reinforcement 10.41.93.61.9-0.60.2-1.3-0.40.4-1.91.40.40.51.8-1.9-1.91.8-1.8
Light reinforcement 20.81.84.01.3-1.81.1-2.01.3-1.1-1.52.0-0.9-0.91.8-0.7-1.20.8-0.8
Bone: marrow area1.74.18.2-2.02.8-2.32.9-2.32.12.1-2.82.12.0-2.00.41.2-0.70.6
Bone: maximum diameter0.71.43.2-0.81.6-1.21.8-1.51.11.0-1.81.21.2-1.40.20.8-0.50.5
Bone: maximum force1.53.05.8-1.12.4-2.02.4-2.32.11.3-2.32.02.0-1.70.10.8-0.40.4
Bone: maximum moment1.83.36.5-1.02.5-2.22.5-2.52.41.1-2.42.22.2-1.6-0.10.6-0.20.2
Mean time between licks in bursts0.21.02.01.4-1.30.9-1.30.6-0.5-1.31.3-0.5-0.41.3-0.6-0.90.8-0.7
Mean num. licks in bursts0.10.20.60.3-0.00.30.20.10.1-0.1-0.3-0.2-0.1-0.80.60.5-0.60.6
Cd content in liver0.80.92.6-1.00.9-1.40.8-1.21.60.8-0.71.31.2-0.1-0.5-0.30.4-0.4
Co content in liver0.91.12.2-0.40.2-1.3-0.2-1.01.50.00.31.31.31.0-1.3-1.31.3-1.3
Cu content in liver0.70.92.2-1.30.9-1.50.5-1.01.00.9-0.31.31.20.4-0.8-0.70.8-0.8
Fe content in liver0.40.51.7-1.30.9-0.90.7-0.40.61.1-0.70.60.5-0.40.10.2-0.10.1
K content in liver0.00.00.2-0.5-0.0-0.30.1-0.1-0.00.4-0.10.20.1-0.20.10.2-0.20.2
Mg content in liver0.20.20.7-0.8-0.10.10.10.5-0.60.7-0.1-0.4-0.5-0.40.60.5-0.60.6
Mn content in liver0.30.40.8-0.60.30.20.50.4-0.50.7-0.5-0.5-0.5-0.80.70.9-0.90.8
Na content in liver1.11.22.60.6-1.51.3-1.51.4-1.6-0.71.4-1.3-1.30.8-0.0-0.30.0-0.0
Rb content in liver1.72.04.2-2.01.8-1.81.8-1.31.41.9-1.81.41.3-1.10.10.6-0.40.3
Se content in liver1.31.53.50.8-1.31.8-1.11.7-1.9-0.71.0-1.8-1.70.20.70.4-0.60.6
Sr content in liver6.65.713.03.6-3.12.6-3.32.1-1.3-3.43.2-1.9-1.62.4-0.8-1.61.1-1.0
Zn content in liver0.60.71.4-1.1-0.20.50.00.9-1.21.0-0.1-0.9-1.0-0.61.20.9-1.01.0
Bone: minimum diameter1.73.26.7-0.92.4-2.22.4-2.62.31.0-2.22.32.3-1.3-0.50.40.1-0.1
Time in familiar zone, hab. session 12.02.25.10.61.1-1.70.7-2.22.2-0.6-0.52.12.30.5-1.5-1.21.5-1.4
Time in novel zone, hab. session 11.01.12.9-0.6-1.01.1-1.01.7-1.70.30.9-1.5-1.60.40.50.3-0.50.4
Total zone transitions, hab. session 12.12.95.90.80.4-1.3-0.5-1.61.7-1.20.81.81.91.9-2.4-2.32.4-2.4
Total locomotion distance, hab. session 11.31.93.71.5-0.3-0.5-0.8-1.01.2-1.61.01.01.21.6-1.9-1.91.9-1.9
Locomotion velocity, hab. session 10.91.32.61.2-0.2-0.4-0.7-0.81.0-1.30.80.81.01.4-1.6-1.61.6-1.6
Time in familiar zone, hab. session 22.32.65.3-1.92.0-1.52.3-1.11.32.0-2.31.11.0-2.01.11.5-1.21.2
Time in novel zone, hab. session 21.11.22.50.9-1.31.1-1.61.0-1.2-1.01.6-1.0-1.01.3-0.6-0.80.6-0.6
Total zone transitions, hab. session 21.62.14.60.41.1-1.60.7-2.12.1-0.5-0.52.02.10.6-1.7-1.21.5-1.4
Total locomotion distance, hab. session 20.81.02.81.7-0.60.0-0.7-0.50.7-1.60.80.50.71.1-1.2-1.21.2-1.2
Locomotion velocity, hab. session 21.01.43.81.9-0.80.2-1.0-0.40.6-1.81.10.40.61.4-1.4-1.41.4-1.4
Novel to familiar place preference ratio0.00.00.10.4-0.10.20.1-0.10.0-0.1-0.2-0.1-0.0-0.20.10.3-0.20.2
Novelty place preference0.00.00.10.10.2-0.10.3-0.30.30.0-0.30.20.3-0.2-0.00.2-0.10.1
Time in novel zone, NPP test0.10.10.2-0.00.3-0.20.4-0.30.30.2-0.50.20.3-0.30.10.3-0.20.2
Total zone transitions, NPP test0.40.61.00.9-0.1-0.4-0.2-0.71.0-0.90.30.80.90.8-1.0-1.01.0-1.0
Total locomotion distance, NPP test0.20.31.11.1-0.3-0.0-0.1-0.30.7-0.90.10.30.50.3-0.5-0.40.4-0.4
Locomotion velocity, NPP test0.40.51.71.3-0.4-0.1-0.3-0.40.9-1.10.40.50.70.7-0.9-0.80.8-0.7
Intraocular pressure0.00.00.1-0.20.3-0.20.1-0.10.30.1-0.10.10.10.2-0.2-0.20.2-0.2
Delta distance traveled before/after self-admin1.21.32.71.3-1.41.6-1.31.4-1.4-1.21.3-1.5-1.40.60.2-0.1-0.20.2
Delta ambulatory time before/after self-admin0.71.22.51.3-1.61.4-1.41.2-1.2-1.21.3-1.2-1.10.70.1-0.3-0.00.1
Parametrial fat weight0.92.14.61.6-1.92.1-1.61.7-1.8-1.41.5-1.9-1.80.50.60.1-0.40.4
Pavlov. Cond. lever latency0.10.10.30.0-0.40.0-0.50.2-0.3-0.20.5-0.1-0.10.5-0.4-0.40.3-0.3
Pavlov. Cond. magazine entry latency0.50.71.40.5-0.51.2-0.30.9-1.1-0.30.2-1.2-1.2-0.51.00.7-0.90.9
Pavlov. Cond. change in total contacts0.10.10.30.6-0.40.5-0.40.3-0.3-0.50.3-0.4-0.30.10.1-0.1-0.00.1
Pavlov. Cond. index score0.10.20.50.5-0.30.7-0.20.4-0.5-0.40.2-0.6-0.6-0.10.40.2-0.20.2
Pavlov. Cond. latency score0.10.20.40.5-0.20.6-0.10.3-0.4-0.30.0-0.6-0.5-0.20.50.3-0.30.3
Pavlov. Cond. lever contacts0.30.40.9-0.40.6-0.00.8-0.10.10.6-0.9-0.1-0.1-1.00.80.9-0.80.8
Pavlov. Cond. magazine entry number0.20.30.6-0.40.3-0.80.1-0.50.60.3-0.00.70.70.4-0.7-0.50.6-0.6
Pavlov. Cond. intertrial magazine entries1.31.63.41.0-0.8-0.4-1.2-0.40.7-1.21.30.80.91.7-1.8-1.81.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.5-0.30.7-0.20.4-0.6-0.40.2-0.6-0.6-0.10.50.3-0.30.3
Pavlov. Cond. response bias0.40.41.1-0.20.10.50.40.4-0.40.3-0.5-0.6-0.6-0.91.10.9-1.01.0
Pavlov. Cond. lever latency0.60.93.5-1.91.3-1.30.8-0.80.61.5-0.70.90.7-0.2-0.2-0.10.2-0.3
Pavlov. Cond. magazine entry latency0.81.12.41.0-1.21.5-0.61.4-1.3-0.70.5-1.4-1.4-0.41.00.8-1.01.0
Pavlov. Cond. change in total contacts0.10.21.21.1-0.10.10.1-0.50.5-0.8-0.10.30.4-0.0-0.4-0.10.2-0.1
Pavlov. Cond. index score0.30.41.21.1-0.70.9-0.10.6-0.5-0.70.0-0.7-0.6-0.50.60.7-0.70.8
Pavlov. Cond. latency score0.50.81.81.3-1.11.3-0.51.0-0.9-0.90.4-1.1-1.0-0.30.70.6-0.70.8
Pavlov. Cond. lever contacts0.40.52.61.6-1.01.0-0.50.6-0.4-1.20.4-0.6-0.5-0.00.20.3-0.30.4
Pavlov. Cond. magazine entry number0.50.61.4-0.80.9-1.20.5-1.00.90.6-0.41.11.00.3-0.7-0.60.7-0.7
Pavlov. Cond. intertrial magazine entries1.32.96.1-1.52.1-2.51.7-2.22.21.3-1.52.42.3-0.2-1.0-0.40.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.51.21.1-0.81.0-0.30.6-0.5-0.80.1-0.8-0.7-0.40.60.6-0.60.7
Pavlov. Cond. response bias0.10.21.01.0-0.30.40.20.00.2-0.6-0.3-0.10.0-0.40.30.5-0.40.5
Time in closed arm before self-admin0.40.61.4-0.61.2-1.01.0-1.01.10.6-0.91.01.0-0.5-0.20.10.1-0.1
Time in closed arm after self-admin0.20.20.5-0.70.1-0.30.40.00.10.6-0.40.20.1-0.70.40.4-0.50.5
Time in open arm before self-admin1.41.74.71.4-2.21.6-1.81.5-1.4-1.31.7-1.3-1.30.90.0-0.40.1-0.0
Time in open arm after self-admin0.20.20.50.7-0.40.5-0.50.2-0.3-0.70.5-0.3-0.20.5-0.3-0.40.3-0.3
Bone: periosteal estimation1.33.05.9-1.32.4-2.12.4-2.32.01.3-2.32.02.0-1.5-0.10.7-0.20.2
Bone: periosteal perimeter1.02.04.1-1.02.0-1.81.8-2.01.71.0-1.71.81.8-0.9-0.40.20.2-0.2
Bone: post-yield work1.73.06.0-2.12.4-1.82.5-1.61.62.1-2.41.51.3-1.80.61.2-0.80.8
Progressive ratio test 1 active lever presses0.20.41.30.1-0.1-0.90.1-0.81.1-0.1-0.11.11.10.2-0.6-0.50.5-0.5
Progressive ratio test 1 breakpoint0.20.41.30.1-0.2-0.90.1-0.81.1-0.1-0.01.11.10.2-0.6-0.50.5-0.4
Progressive ratio test 1 inactive lever presses0.82.04.3-1.71.6-2.11.6-1.61.71.5-1.61.81.7-0.9-0.00.3-0.10.1
Progressive ratio test 2 active lever presses0.60.92.7-1.60.4-0.80.9-0.00.31.5-1.00.40.3-1.10.91.0-1.01.0
Progressive ratio test 2 breakpoint0.81.03.2-1.80.5-0.91.0-0.10.31.7-1.10.50.3-1.20.91.0-1.01.0
Progressive ratio test 2 inactive lever presses0.82.75.4-2.01.8-2.31.9-1.82.01.8-1.92.11.9-1.1-0.00.4-0.20.2
Incentive Sensitization - Responses0.82.26.4-2.51.5-1.41.8-0.50.62.4-1.90.80.6-1.71.11.4-1.21.2
Incentive Sensitization - Breakpoint0.92.05.8-2.41.3-1.11.7-0.30.42.3-1.70.50.3-1.61.11.4-1.31.2
Sum of active levers in priming session hrs 5-60.30.20.60.80.70.10.0-0.60.1-0.70.10.20.20.4-0.6-0.60.6-0.7
Progressive ratio0.10.41.31.1-0.30.1-0.5-0.50.3-1.00.50.20.30.7-0.9-0.80.8-0.8
Food seeking constrained by brief footshock7.99.928.05.3-1.40.1-2.3-1.82.0-4.92.61.52.13.3-3.8-3.93.8-3.7
Seeking ratio, punishment vs. effort0.40.81.51.00.3-0.60.0-1.11.2-1.00.11.11.20.6-1.1-1.01.1-1.0
Retroperitoneal fat weight2.19.322.01.1-2.84.4-2.14.1-4.7-0.81.8-4.7-4.7-0.32.71.8-2.22.2
Reaction time number correct0.20.83.51.4-1.90.8-1.21.0-0.2-1.21.1-0.5-0.40.40.2-0.3-0.10.2
Reaction time mean minus median0.00.20.4-0.60.4-0.10.50.1-0.10.6-0.5-0.1-0.1-0.50.60.4-0.40.4
Reaction time mean minus median AUC0.00.30.7-0.80.3-0.00.40.4-0.20.8-0.4-0.2-0.3-0.60.80.6-0.60.6
Reaction time num false alarms0.10.20.60.20.7-0.10.2-0.80.3-0.2-0.10.20.20.1-0.5-0.30.5-0.6
Reaction time num false alarms AUC0.30.61.31.1-0.00.2-0.6-0.50.3-1.10.70.10.20.9-1.0-1.11.1-1.1
Reaction time trials correct on left0.20.83.51.4-1.90.8-1.21.0-0.2-1.21.1-0.5-0.40.40.2-0.3-0.10.2
Reaction time trials on left0.20.83.51.4-1.90.8-1.21.0-0.2-1.21.1-0.5-0.40.40.2-0.3-0.10.2
Reaction time mean0.61.44.4-2.11.7-1.11.5-0.60.61.9-1.50.70.5-1.10.70.8-0.60.6
Reaction time mean AUC0.41.03.6-1.91.2-0.71.2-0.10.11.7-1.20.2-0.0-1.00.90.9-0.80.8
Median of all reaction times0.81.34.5-2.11.5-1.11.4-0.50.51.9-1.40.60.4-1.00.60.8-0.70.6
Reaction time omissions0.30.40.90.6-0.1-0.1-0.5-0.30.4-0.70.60.30.41.0-0.9-0.90.9-0.9
Reaction time false alarm rate0.40.51.40.30.9-0.20.0-1.00.4-0.40.10.30.40.6-1.1-0.91.1-1.2
Reaction time premature initiation rate0.00.00.1-0.10.10.00.20.20.00.1-0.2-0.1-0.1-0.40.40.2-0.30.3
Reaction time premature initiations0.10.30.70.6-0.90.6-0.40.8-0.2-0.40.3-0.5-0.4-0.30.60.3-0.50.6
Std. dev. reaction times0.20.71.8-1.31.3-0.81.1-0.50.41.2-1.10.50.3-0.70.50.5-0.40.3
Reaction time trials completed0.20.83.51.4-1.90.8-1.21.0-0.2-1.21.1-0.5-0.40.40.2-0.3-0.10.2
Reaction time trials AUC0.20.73.01.2-1.70.8-1.01.0-0.2-1.00.9-0.6-0.50.20.4-0.0-0.30.4
Run reversals in cocaine runway, females0.30.41.0-1.00.7-0.40.8-0.10.11.0-0.80.20.1-0.70.50.6-0.60.5
Run reversals in cocaine runway, males0.10.10.5-0.7-0.0-0.20.20.30.00.6-0.20.0-0.0-0.40.40.4-0.50.4
Latency to leave start box in cocaine runway0.30.41.3-0.71.1-0.80.8-1.00.70.6-0.70.70.7-0.2-0.2-0.00.2-0.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.10.5-0.20.3-0.40.20.1-0.30.20.2-0.0-0.1-0.00.2-0.2
Latency to leave start box in cocaine runway, M1.21.12.5-1.41.6-1.41.3-1.21.11.2-1.21.21.1-0.6-0.10.20.0-0.1
Std. dev. time between licks in bursts1.01.94.41.5-0.90.0-1.3-0.30.5-1.61.40.50.62.1-1.9-1.91.9-1.8
Total sessions with >9 infusions0.70.81.7-1.10.9-1.31.1-0.91.11.0-1.01.21.1-0.70.10.3-0.10.2
Short access day 1 total inactive lever presses0.81.74.6-2.11.4-1.21.6-0.50.52.0-1.70.70.5-1.50.91.2-1.01.0
Short access day 10 total inactive lever presses0.00.20.8-0.40.9-0.60.6-0.60.60.4-0.60.50.5-0.2-0.1-0.00.1-0.2
Short access day 1 total infusions0.10.20.5-0.70.1-0.30.40.10.00.7-0.40.10.0-0.60.50.5-0.50.5
Short access day 10 total infusions0.00.10.1-0.3-0.30.0-0.10.3-0.20.20.0-0.1-0.1-0.20.40.2-0.30.3
Short access total infusions0.10.10.3-0.2-0.50.2-0.10.4-0.30.20.1-0.2-0.3-0.30.50.3-0.40.5
Short access day 1 locomotion0.81.34.3-2.10.9-0.91.3-0.10.21.9-1.30.40.2-1.31.11.2-1.11.1
Short access day 10 total locomotion0.31.22.7-0.01.1-1.40.7-1.61.6-0.0-0.61.61.60.2-1.0-0.71.0-1.0
Short access total locomotion0.40.61.30.70.1-0.7-0.1-1.01.1-0.70.21.01.10.6-0.9-0.91.0-0.9
One hour access (0.3 mA shock)2.93.46.6-2.62.2-2.42.3-1.71.92.3-2.32.01.8-1.50.30.8-0.50.5
Compulsive drug intake1.21.83.2-1.71.7-1.81.7-1.41.61.5-1.61.51.4-1.0-0.00.5-0.20.2
One hour access (shock baseline)0.30.92.9-1.70.5-0.50.90.2-0.11.6-0.90.1-0.1-1.11.11.0-1.01.0
Social response proportion1.41.84.8-2.21.7-1.11.7-0.60.32.1-1.80.50.4-1.61.01.3-1.01.0
Social responses2.63.46.9-2.62.6-2.22.4-1.71.72.4-2.41.71.5-1.60.31.0-0.50.5
Social time2.23.58.00.21.8-2.21.1-2.82.8-0.3-0.92.62.70.5-2.0-1.41.8-1.8
Soleus weight0.00.10.40.30.6-0.10.6-0.50.2-0.1-0.60.20.2-0.60.20.4-0.20.2
Bone: stiffness1.42.55.2-1.32.3-2.02.1-2.11.81.2-2.01.91.9-1.2-0.20.4-0.0-0.0
Tibialis anterior weight0.72.34.41.1-1.12.1-0.21.6-1.9-0.5-0.0-2.0-1.9-1.21.91.7-1.81.8
Time to tail flick, vehicle, before self-admin0.30.30.80.70.1-0.40.0-0.70.9-0.60.00.60.70.2-0.7-0.60.6-0.6
Time to tail flick, vehicle, after self-admin0.51.13.2-1.81.8-0.81.4-0.50.21.6-1.40.30.2-1.10.70.8-0.60.5
Time to tail flick, test, before self-admin1.72.05.32.3-1.00.0-1.2-0.70.7-2.21.30.70.91.5-1.7-1.71.7-1.6
Time to tail flick, test, after self-admin0.10.10.40.2-0.20.5-0.20.5-0.6-0.10.2-0.6-0.6-0.20.30.2-0.30.3
Delta time to tail flick, vehicle, before/after SA0.60.62.3-1.50.7-0.20.70.3-0.61.3-0.7-0.3-0.4-0.60.90.9-0.80.7
Delta time to tail flick, test, before/after SA0.91.12.7-1.70.8-0.00.90.5-0.51.6-1.0-0.5-0.7-1.21.21.2-1.21.1
Tibia length1.84.98.8-1.82.8-3.02.8-2.82.71.8-2.72.92.8-1.7-0.30.6-0.10.1
Ambulatory time before self-admin0.92.75.61.21.3-1.30.5-2.42.1-1.2-0.31.92.10.8-2.1-1.51.9-2.0
Ambulatory time after self-admin1.52.46.42.50.2-0.0-0.6-1.41.1-2.30.80.81.11.6-2.1-1.82.0-2.0
Bone: tissue strength0.91.02.51.6-0.2-0.2-0.5-0.80.9-1.50.60.70.91.0-1.2-1.21.2-1.2
Total heroin consumption0.10.10.40.60.20.3-0.2-0.1-0.1-0.50.2-0.1-0.10.6-0.4-0.30.4-0.4
Bone: trabecular number0.20.31.11.0-0.70.6-0.70.3-0.3-1.00.7-0.3-0.20.6-0.3-0.50.4-0.4
Bone: trabecular spacing0.10.10.3-0.10.00.10.30.1-0.10.3-0.3-0.1-0.1-0.40.30.5-0.40.4
Bone: trabecular thickness0.10.20.3-0.50.4-0.10.5-0.1-0.10.5-0.5-0.0-0.1-0.60.50.5-0.40.4
Bone: trabecular tissue density0.71.22.5-0.8-0.71.0-0.31.6-1.50.80.2-1.5-1.6-0.51.31.0-1.21.2
Water consumed over 24 hours0.30.61.60.20.6-0.90.4-1.21.3-0.3-0.31.11.20.1-0.8-0.60.7-0.7
Number of responses in last shaping day0.91.23.5-1.90.9-0.41.10.3-0.31.7-1.1-0.2-0.3-1.21.31.2-1.21.1