Hub : Genes

Vom1r47

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Vom1r47 0.14 0.09 3.3e-06 0.01 0.03 0.02 0.02 2.3e-03 2.5e-05 1.5e-04 3.0e-04
2 RMTg isoform ratio XM_063270359.1 0.29 0.18 6.8e-04 0.14 0.12 0.15 0.12 2.0e-04 4.9e-04 1.1e-04 5.0e-04
3 Brain gene expression Vom1r47 0.08 0.06 1.9e-08 0.08 0.08 0.08 0.08 1.2e-07 5.0e-08 5.9e-08 5.0e-08
4 RMTg alternative TSS XM_063270359.1 0.3 0.18 1.9e-03 0.04 0.09 0.11 0.1 2.6e-02 1.8e-03 8.0e-04 1.2e-03
5 RMTg isoform ratio XM_063270370.1 0.08 0.07 9.8e-03 0.08 0.05 0.03 0.05 4.3e-03 1.6e-02 6.7e-02 1.7e-02
6 NAcc intron excision ratio chr1_81546723_81555570 0.02 0.02 7.1e-03 0.01 0.01 0.01 0.01 4.0e-03 5.3e-03 1.2e-02 7.0e-03
7 RMTg isoform ratio XM_063270367.1 0.45 0.2 6.3e-04 0.14 0.14 0.14 0.14 1.4e-04 1.2e-04 1.3e-04 1.4e-04
8 RMTg alternative TSS XM_063270367.1 0.28 0.18 5.0e-03 0.03 0.07 0.09 0.08 5.1e-02 7.9e-03 1.9e-03 4.6e-03
9 Brain isoform ratio XM_063270370.1 0.03 0.02 5.3e-04 0.03 0.03 0.03 0.03 1.3e-03 6.3e-04 1.8e-03 1.9e-03
10 pVTA intron excision ratio chr1_81486834_81507518 0.04 0.03 9.3e-03 0 0.01 -0 0 2.1e-01 3.3e-02 3.8e-01 3.0e-01
11 RMTg gene expression Vom1r47 0.45 0.2 5.0e-05 0.04 0.16 0.12 0.16 3.3e-02 4.8e-05 5.1e-04 4.1e-05
12 pVTA alternative TSS XM_063270359.1 0.09 0.07 5.1e-03 0.01 0.02 0.02 0.02 4.9e-02 7.0e-03 4.6e-03 1.8e-02
13 pVTA gene expression Vom1r47 0.48 0.18 5.6e-15 0.17 0.18 0.18 0.18 1.0e-13 2.2e-14 2.0e-14 3.0e-14
14 pVTA alternative TSS XM_063270367.1 0.17 0.11 1.1e-04 0.05 0.05 0.05 0.04 1.2e-04 6.4e-05 4.8e-05 1.5e-04
15 pVTA alternative TSS XM_063270359.1 0.17 0.11 1.1e-04 0.05 0.05 0.05 0.04 1.3e-04 6.6e-05 4.6e-05 1.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.00.10.20.2-0.2-0.2-0.20.4-0.3-0.20.10.30.3-0.10.20.1-0.20.2
Area under the delay curve0.30.41.01.00.90.80.6-0.70.5-0.8-0.6-0.6-0.50.2-0.30.00.1-0.2
BMI with tail0.41.22.40.71.31.50.8-1.51.6-0.5-0.7-1.5-1.5-0.3-1.0-0.70.9-1.0
BMI without tail0.10.30.9-0.3-0.0-0.1-0.5-0.10.10.40.60.00.0-1.0-0.7-0.70.8-0.8
Body weight1.04.38.7-2.3-2.5-2.1-2.91.7-1.72.42.91.81.6-2.5-1.0-1.71.3-1.3
Weight adjusted by age0.40.61.20.4-0.4-0.8-0.21.0-1.1-0.40.11.01.10.51.00.7-0.90.9
Bone surface1.83.26.7-1.7-2.6-2.4-2.32.4-2.11.62.22.22.1-1.10.4-0.3-0.10.2
Bone volume1.62.96.1-1.7-2.5-2.2-2.22.2-1.81.62.12.01.9-1.20.2-0.50.0-0.0
Breakpoint value in progressive ratio session0.20.20.60.30.10.70.2-0.50.8-0.3-0.2-0.7-0.70.1-0.3-0.10.2-0.2
Number of licking bursts0.00.00.1-0.4-0.0-0.00.0-0.10.20.3-0.0-0.1-0.10.30.1-0.0-0.10.1
Context. condit. distance diff. score0.30.30.90.90.60.30.6-0.10.0-0.9-0.7-0.00.00.60.60.6-0.50.5
Locomotion velocity, session 13.33.57.41.60.8-0.61.60.8-1.0-1.9-1.81.11.32.62.72.7-2.72.7
Locomotion distance, session 12.43.05.90.3-1.1-2.0-0.42.3-2.2-0.60.12.32.41.12.31.8-2.02.1
Locomotion velocity, session 21.21.33.11.10.7-0.11.20.2-0.4-1.3-1.40.40.51.71.51.8-1.61.6
Locomotion distance, session 21.31.83.5-0.5-1.2-1.8-0.71.8-1.80.20.51.91.90.61.41.1-1.31.4
Locomotion velocity, session 30.10.10.40.00.4-0.00.5-0.10.0-0.2-0.50.00.00.60.50.5-0.40.5
Locomotion distance, session 30.50.51.10.70.1-0.40.20.6-0.8-0.7-0.30.70.80.81.00.9-0.90.9
Stereotopy head waving bouts, day 30.10.10.2-0.40.10.20.1-0.40.50.4-0.0-0.3-0.4-0.2-0.2-0.30.3-0.3
Stereotopy head waving duration, day 30.10.10.3-0.40.10.10.1-0.30.50.4-0.0-0.3-0.3-0.3-0.2-0.30.3-0.3
Locomotion velocity, session 70.30.41.1-0.1-0.2-0.60.20.6-0.3-0.1-0.30.60.60.71.00.8-0.90.9
Locomotion distance, session 70.40.51.20.50.2-0.30.60.4-0.3-0.6-0.70.50.51.01.01.1-1.11.1
Stereotopy head waving bouts, day 70.20.30.7-0.8-0.5-0.3-0.60.1-0.20.80.70.10.0-0.6-0.3-0.50.5-0.4
Stereotopy head waving duration, day 70.20.20.5-0.7-0.6-0.4-0.70.3-0.20.70.70.20.2-0.6-0.3-0.50.4-0.4
Locomotion velocity, session 80.91.02.31.00.3-0.20.80.5-0.5-1.2-1.00.50.61.41.51.5-1.41.4
Locomotion distance, session 80.50.81.70.70.0-0.50.40.7-0.8-0.8-0.50.80.91.01.31.2-1.21.2
Degree of sensitization distance0.00.00.0-0.1-0.1-0.10.10.00.00.1-0.10.00.00.10.10.2-0.10.1
Degree of sensitization stereotypy0.10.10.2-0.3-0.10.1-0.3-0.10.00.40.4-0.2-0.2-0.5-0.4-0.50.5-0.5
Conditioned locomotion0.50.61.20.90.3-0.10.60.3-0.4-0.9-0.70.40.41.01.11.1-1.01.0
Cocaine response after cond. corrected1.41.73.5-1.20.51.10.2-1.71.91.1-0.1-1.6-1.8-0.7-1.7-1.31.5-1.4
Cocaine response after cond. not corrected0.80.92.7-1.7-0.8-0.3-1.0-0.10.31.61.0-0.1-0.3-1.1-1.1-1.21.1-1.0
Cocaine response before conditioning3.54.29.6-0.8-2.5-2.7-2.23.1-3.10.82.12.92.9-0.61.20.3-0.90.9
Saline control response1.01.43.41.10.1-0.50.70.9-0.8-1.3-0.80.80.91.51.81.6-1.71.7
Bone: connectivity density0.10.20.50.70.50.40.5-0.20.2-0.7-0.6-0.3-0.20.40.20.4-0.30.2
Bone: cortical apparent density0.30.41.20.10.2-0.30.60.2-0.4-0.4-0.70.40.41.00.71.1-1.01.0
Bone: cortical area0.60.92.3-0.2-1.3-1.1-1.31.5-1.10.31.21.21.3-0.70.3-0.2-0.10.1
Bone: cortical porosity0.20.30.80.30.40.80.4-0.70.9-0.3-0.3-0.8-0.80.0-0.3-0.30.3-0.3
Bone: cortical porosity0.20.30.6-0.4-0.10.4-0.2-0.40.70.40.3-0.6-0.6-0.5-0.6-0.70.7-0.6
Bone: cortical thickness0.30.51.21.10.70.50.8-0.10.4-1.1-0.9-0.2-0.10.80.70.7-0.60.6
Bone: cortical thickness0.20.30.70.1-0.1-0.50.30.5-0.5-0.3-0.30.60.60.60.70.8-0.80.8
Bone: cortical tissue density0.30.41.10.00.2-0.30.60.1-0.4-0.3-0.70.40.40.90.71.0-0.90.9
Condit. Reinf. active minus inactive responses0.10.10.3-0.5-0.10.10.1-0.20.50.3-0.1-0.2-0.3-0.0-0.0-0.00.1-0.1
Condit. Reinf. active-inactive response ratio0.60.71.90.50.81.10.8-1.01.4-0.4-0.8-1.2-1.20.1-0.4-0.10.4-0.4
Condit. Reinf. active responses0.20.30.9-1.0-0.9-0.7-0.60.5-0.30.80.60.40.3-0.40.0-0.10.1-0.1
Condit. Reinf. inactive responses1.51.94.0-1.2-1.8-1.9-1.61.7-2.01.01.41.81.8-0.50.60.1-0.40.4
Incentive salience index mean0.10.20.5-0.5-0.7-0.6-0.40.6-0.20.40.40.50.4-0.20.20.1-0.10.1
Condit. Reinf. lever presses0.50.61.6-0.4-1.2-1.0-0.91.3-1.00.30.81.11.1-0.30.40.3-0.40.4
Condit. Reinf. active minus inactive responses1.92.55.6-0.8-1.9-2.1-1.72.2-2.40.71.52.22.2-0.40.90.3-0.70.7
Condit. Reinf. active-inactive response ratio2.63.15.8-1.6-2.4-2.3-2.22.2-2.31.52.12.22.1-1.20.3-0.3-0.10.2
Condit. Reinf. active responses1.82.45.9-0.2-1.6-2.0-1.32.3-2.40.11.12.32.30.11.40.8-1.21.2
Condit. Reinf. inactive responses0.20.30.91.00.2-0.10.20.4-0.5-0.8-0.20.40.50.50.80.5-0.60.6
Condit. Reinf. lever presses0.50.61.9-0.0-0.6-0.1-1.10.4-0.40.31.20.10.2-1.4-0.8-1.21.0-1.1
Condit. Reinf. lever reinforcers received2.12.97.1-0.3-1.8-2.2-1.52.6-2.70.31.32.52.5-0.01.50.7-1.11.1
Conditioned reinforcement - actives0.40.72.3-1.50.0-0.6-0.6-0.2-0.11.40.70.20.1-1.0-1.0-0.91.0-1.0
Conditioned reinforcement - inactives1.21.84.0-1.1-1.4-2.0-1.41.8-1.91.01.32.01.9-0.60.40.1-0.30.3
Conditioned locomotion0.20.30.8-0.9-0.4-0.3-0.5-0.1-0.00.80.50.0-0.0-0.6-0.6-0.60.5-0.5
Patch foraging indifference point 0 sec0.71.34.12.01.20.81.3-0.30.1-1.9-1.4-0.3-0.11.21.11.2-1.11.0
Patch foraging indifference point AUC0.40.51.30.00.81.00.6-1.11.1-0.0-0.5-1.1-1.1-0.0-0.6-0.40.5-0.5
Delay disc. indifference point, 0s delay1.11.23.61.90.50.10.80.7-0.6-1.7-0.80.50.71.11.31.3-1.31.2
Delay disc. indifference point, 16s delay1.41.52.9-1.00.10.9-0.3-1.31.41.10.5-1.4-1.5-1.1-1.7-1.51.6-1.6
Delay disc. indifference point, 2s delay0.50.61.61.21.20.61.1-0.70.3-1.1-1.1-0.3-0.20.80.20.6-0.40.3
Delay disc. indifference point, 24s delay0.50.61.4-0.3-0.00.9-0.0-0.91.10.40.1-1.1-1.2-0.4-0.9-0.70.8-0.7
Delay disc. indifference point, 4s delay0.10.10.1-0.10.1-0.2-0.2-0.1-0.20.20.20.20.2-0.3-0.3-0.20.3-0.3
Delay disc. indifference point, 8s delay0.30.31.41.20.90.60.7-0.40.1-1.0-0.7-0.3-0.20.40.10.3-0.20.1
Indifference point function ln k2.74.711.3-0.6-2.1-3.0-1.83.0-3.40.51.63.33.3-0.11.71.0-1.41.4
Indifference point function log k2.74.711.3-0.6-2.1-3.0-1.83.0-3.40.51.63.33.3-0.11.71.0-1.41.4
Patch foraging total patch changes 0 sec0.71.24.02.01.10.81.3-0.20.1-1.9-1.3-0.2-0.11.21.11.2-1.01.0
Patch foraging total patch changes 12 sec0.30.40.90.30.70.90.5-0.90.9-0.2-0.4-1.0-1.0-0.2-0.5-0.40.5-0.5
Patch foraging total patch changes 18 sec0.50.81.51.21.21.11.2-0.90.6-1.1-1.2-0.8-0.80.90.40.5-0.30.3
Patch foraging total patch changes 24 sec0.30.61.1-1.0-0.40.2-0.5-0.50.51.00.6-0.5-0.6-0.9-1.0-1.00.9-0.9
Patch foraging total patch changes 6 sec0.60.81.80.81.11.40.9-1.21.2-0.6-0.8-1.3-1.30.0-0.5-0.30.5-0.5
Patch foraging time to switch 0 sec3.06.110.7-1.81.02.10.2-3.23.21.80.2-3.0-3.2-1.7-3.3-2.73.1-3.0
Patch foraging water rate 0 sec0.81.63.01.1-0.2-0.90.21.5-1.5-1.1-0.31.41.61.01.71.5-1.61.6
Patch foraging water rate 12 sec1.63.57.21.2-0.6-1.8-0.22.3-2.7-1.2-0.02.52.71.22.31.9-2.12.1
Patch foraging water rate 18 sec1.11.73.11.0-0.2-1.00.11.5-1.6-1.1-0.31.51.61.11.81.5-1.71.6
Patch foraging water rate 24 sec0.91.32.50.5-0.4-1.10.01.3-1.5-0.6-0.21.41.50.91.61.3-1.41.4
Patch foraging water rate 6 sec3.75.310.2-2.1-3.1-3.2-2.83.1-2.91.92.63.02.9-1.20.8-0.2-0.40.4
Seeking ratio, delayed vs. immediate footshock1.41.75.12.30.40.10.80.9-0.9-2.1-0.90.60.91.31.61.5-1.61.5
Distance traveled before self-admin3.03.96.91.8-1.0-1.4-0.22.6-2.5-1.7-0.12.22.51.42.62.1-2.52.5
Distance traveled after self-admin2.32.99.73.10.50.71.20.8-0.5-2.8-1.40.20.51.92.02.0-2.12.0
Extensor digitorum longus weight0.41.53.6-1.1-1.2-0.7-1.70.6-0.61.31.80.50.5-1.9-1.2-1.51.4-1.4
Bone: elastic displacement0.50.61.31.11.10.91.0-0.70.5-1.0-1.0-0.7-0.60.70.40.4-0.30.2
Bone: elastic work0.20.30.80.7-0.2-0.4-0.20.8-0.9-0.50.20.70.8-0.00.50.3-0.40.3
Bone: endosteal estimation1.94.18.2-2.0-2.8-2.3-2.92.3-2.12.12.82.12.0-2.0-0.4-1.20.7-0.6
Bone: endosteal perimeter1.12.44.6-1.3-2.1-1.9-2.11.9-1.81.42.11.81.7-1.40.0-0.60.3-0.2
Epididymis fat weight0.61.93.6-1.7-1.40.2-1.5-0.10.71.81.6-0.7-0.9-1.8-1.6-1.91.6-1.5
Delta time in closed arm before/after self-admin0.10.10.50.30.70.30.5-0.40.3-0.3-0.4-0.2-0.20.2-0.10.1-0.0-0.0
Delta time in open arm before/after self-admin1.11.02.4-0.6-1.5-1.3-1.11.5-1.30.51.01.41.3-0.20.70.2-0.50.5
Diff in mean of infusions in LGA sessions0.50.61.41.20.6-0.10.60.5-0.7-1.1-0.60.50.70.50.90.9-0.90.8
Delay discount exponential model param0.20.30.7-0.9-0.8-0.7-0.50.6-0.40.70.50.50.5-0.10.30.0-0.20.2
Extinction: sum of active levers before priming0.20.20.40.6-0.20.30.30.10.2-0.6-0.3-0.1-0.10.50.50.5-0.50.6
Active lever presses in extinction session 61.61.53.3-1.8-0.60.2-0.9-0.80.91.71.0-0.8-1.0-1.5-1.6-1.51.6-1.5
Bone: final force1.42.24.6-1.0-2.1-1.9-1.82.2-1.80.91.71.91.9-1.00.3-0.2-0.20.2
Bone: final moment1.72.76.2-0.9-2.3-2.2-2.02.5-2.10.81.82.22.2-1.00.5-0.0-0.40.4
Food consumed during 24 hour testing period0.70.92.0-0.6-1.3-1.2-1.21.3-1.40.61.11.21.2-0.70.2-0.1-0.10.1
Glucose1.21.84.02.01.91.51.8-1.21.1-1.9-1.8-1.1-1.01.10.30.8-0.40.4
Heart weight1.01.53.3-1.2-1.8-1.1-1.81.2-1.01.31.80.90.8-1.5-0.6-1.00.7-0.7
Delay discount hyperbolic model param0.30.41.1-1.1-1.0-0.8-0.70.7-0.40.90.60.60.5-0.20.2-0.1-0.10.2
Intermittent access intake day 1-15 change0.40.81.8-1.2-1.3-1.1-1.10.9-0.91.01.10.90.8-0.6-0.0-0.30.1-0.0
Intermittent access intake escalation0.61.32.9-1.7-1.7-1.4-1.51.1-1.01.51.51.11.0-0.9-0.2-0.50.3-0.2
Intermittent access intake escalation 20.30.40.70.3-0.6-0.5-0.20.9-0.8-0.30.10.70.70.40.70.6-0.70.8
Intermitt. access day 1 inactive lever presses0.51.94.7-2.2-1.9-1.6-1.81.1-1.12.01.81.11.0-1.2-0.5-0.80.6-0.5
Intermitt. access day 15 inactive lever presses1.42.96.1-2.5-2.4-1.8-2.31.3-1.32.32.31.31.1-1.7-0.7-1.20.8-0.8
Intermitt. access escalation Index0.20.20.60.40.40.70.5-0.60.7-0.4-0.5-0.7-0.70.2-0.3-0.00.1-0.1
Intermittent access day 1 total infusions0.30.51.4-1.2-0.4-0.7-0.80.2-0.41.10.80.50.4-0.9-0.6-0.70.6-0.7
Intermittent access day 15 total infusions0.91.44.2-2.1-1.2-1.2-1.40.5-0.71.91.40.80.6-1.3-0.9-1.00.9-0.8
Intermittent access terminal intake (last 3 days)0.71.02.7-1.7-0.9-1.2-1.20.5-0.71.51.20.80.7-1.0-0.6-0.70.6-0.6
Intermittent access total infusions1.11.33.7-1.9-1.0-1.4-1.40.6-0.91.81.41.00.8-1.2-0.7-0.80.7-0.7
Intermittent access day 1 locomotion0.81.02.2-1.5-1.0-1.3-1.20.8-0.91.31.21.00.9-0.9-0.5-0.60.4-0.4
Intermittent access day 15 total locomotion0.61.02.9-0.2-0.7-1.5-0.61.4-1.70.10.51.61.60.00.80.6-0.70.7
Intermittent access total locomotion1.92.24.5-1.8-1.8-2.1-1.81.7-1.91.61.71.91.8-1.0-0.0-0.30.1-0.0
Intermittent access standard deviation0.10.20.40.60.50.50.5-0.30.3-0.6-0.5-0.3-0.30.40.10.3-0.20.2
Left kidney weight3.114.626.2-3.6-5.1-5.0-5.04.8-4.73.54.84.64.4-2.90.4-1.10.2-0.1
Right kidney weight3.716.732.0-4.4-5.5-4.9-5.74.5-4.44.45.54.34.0-3.8-0.5-2.11.1-1.1
Cocaine induced anxiety0.71.12.7-1.1-1.6-1.3-1.31.3-1.21.01.21.21.1-0.50.3-0.1-0.10.2
Post-drug Anxiety0.91.02.8-1.7-1.5-0.9-1.30.6-0.41.51.30.50.4-0.9-0.3-0.70.5-0.4
Baseline Anxiety0.40.50.90.40.90.90.7-1.01.0-0.4-0.7-0.9-0.90.2-0.4-0.10.3-0.3
Tail length1.87.012.5-2.4-3.5-3.5-3.43.3-3.32.43.33.33.2-1.90.4-0.60.00.0
Length with tail2.410.319.9-3.8-4.3-3.7-4.53.2-3.13.84.43.12.9-3.2-0.7-1.91.2-1.2
Length without tail2.47.716.7-4.1-3.5-2.3-3.81.6-1.44.03.81.41.1-3.2-1.8-2.62.1-2.0
Times rat made contact with spout0.10.10.30.40.40.50.2-0.40.4-0.2-0.2-0.5-0.5-0.3-0.4-0.30.4-0.4
Lifetime Intake0.81.02.9-1.7-0.7-1.1-1.10.4-0.71.61.10.80.6-1.1-0.8-0.80.8-0.8
Liver weight, left0.91.52.7-1.4-1.6-1.6-1.71.4-1.21.41.61.41.3-1.1-0.0-0.60.2-0.2
Liver weight, right0.00.00.20.40.2-0.00.00.1-0.1-0.3-0.00.20.2-0.10.10.1-0.10.0
Locomotor activity0.20.30.70.0-0.00.6-0.3-0.30.50.20.4-0.7-0.7-0.6-0.8-0.80.7-0.7
Locomotor testing distance0.40.71.7-0.9-0.60.2-0.9-0.20.31.01.0-0.4-0.5-1.0-1.2-1.31.1-1.1
Locomotor testing rearing0.30.61.6-0.7-1.0-0.4-1.20.6-0.40.91.30.30.3-1.0-0.6-1.00.7-0.7
Locomotion in novel chamber0.50.61.20.71.11.01.0-1.01.0-0.7-0.9-1.0-0.90.5-0.20.10.1-0.1
Locomotion in novel chamber post-restriction0.50.81.90.71.41.10.9-1.40.9-0.6-0.8-1.0-1.0-0.0-0.7-0.20.6-0.6
Fecal boli incidents, locomotor time 10.10.10.50.1-0.3-0.5-0.40.5-0.70.00.40.60.6-0.20.10.0-0.10.0
Change in fecal boli incidents, locomotor task1.91.93.81.61.91.71.9-1.61.5-1.5-1.8-1.5-1.41.20.00.6-0.30.2
Time >=10cm from walls, locomotor time 10.10.10.2-0.40.00.20.0-0.40.40.40.0-0.3-0.4-0.1-0.3-0.30.3-0.3
Bouts of movement, locomotor time 11.82.13.91.80.1-0.50.61.4-1.3-1.8-0.81.11.31.42.01.8-1.91.9
Total resting periods, locomotor time 11.01.12.21.50.4-0.00.80.7-0.6-1.5-0.90.50.71.31.41.4-1.41.4
Rest time, locomotor task time 10.60.71.2-0.9-1.1-1.1-1.11.0-1.00.81.01.00.9-0.50.1-0.2-0.00.0
Distance moved, locomotor task time 10.50.71.41.01.11.21.1-1.01.1-0.9-1.0-1.1-1.00.6-0.00.2-0.00.0
Vertical activity count, locomotor time 11.23.08.32.92.31.72.3-1.10.9-2.6-2.2-1.1-0.81.70.91.3-0.90.8
Time >=10cm from walls, locomotor time 20.30.51.6-0.20.60.90.6-1.11.20.0-0.5-1.1-1.10.2-0.5-0.20.4-0.3
Bouts of movement, locomotor time 20.00.00.00.0-0.1-0.0-0.10.1-0.0-0.00.10.00.0-0.1-0.0-0.10.0-0.0
Total resting periods, locomotor time 20.00.00.00.20.0-0.10.00.2-0.2-0.2-0.00.20.20.10.10.2-0.20.2
Rest time, locomotor task time 20.20.20.80.90.3-0.10.30.4-0.5-0.8-0.30.40.50.40.60.6-0.60.5
Distance moved, locomotor task time 20.10.10.20.30.20.40.3-0.30.4-0.3-0.3-0.4-0.40.10.00.00.00.0
Vertical activity count, locomotor time 20.20.31.21.10.90.50.7-0.40.1-0.9-0.6-0.2-0.10.40.20.3-0.10.1
Light reinforcement 10.81.93.61.90.60.21.30.4-0.4-1.9-1.40.40.51.81.91.9-1.81.8
Light reinforcement 21.21.84.01.31.81.12.0-1.31.1-1.5-2.0-0.9-0.91.80.71.2-0.80.8
Bone: marrow area1.94.18.2-2.0-2.8-2.3-2.92.3-2.12.12.82.12.0-2.0-0.4-1.20.7-0.6
Bone: maximum diameter0.81.43.2-0.8-1.6-1.2-1.81.5-1.11.01.81.21.2-1.4-0.2-0.80.5-0.5
Bone: maximum force1.73.05.8-1.1-2.4-2.0-2.42.3-2.11.32.32.02.0-1.7-0.1-0.80.4-0.4
Bone: maximum moment1.93.36.5-1.0-2.5-2.2-2.52.5-2.41.12.42.22.2-1.60.1-0.60.2-0.2
Mean time between licks in bursts0.41.02.01.41.30.91.3-0.60.5-1.3-1.3-0.5-0.41.30.60.9-0.80.7
Mean num. licks in bursts0.10.20.60.30.00.3-0.2-0.1-0.1-0.10.3-0.2-0.1-0.8-0.6-0.50.6-0.6
Cd content in liver0.80.92.6-1.0-0.9-1.4-0.81.2-1.60.80.71.31.2-0.10.50.3-0.40.4
Co content in liver1.01.12.2-0.4-0.2-1.30.21.0-1.50.0-0.31.31.31.01.31.3-1.31.3
Cu content in liver0.70.92.2-1.3-0.9-1.5-0.51.0-1.00.90.31.31.20.40.80.7-0.80.8
Fe content in liver0.40.51.7-1.3-0.9-0.9-0.70.4-0.61.10.70.60.5-0.4-0.1-0.20.1-0.1
K content in liver0.00.00.2-0.50.0-0.3-0.10.10.00.40.10.20.1-0.2-0.1-0.20.2-0.2
Mg content in liver0.20.20.7-0.80.10.1-0.1-0.50.60.70.1-0.4-0.5-0.4-0.6-0.50.6-0.6
Mn content in liver0.30.40.8-0.6-0.30.2-0.5-0.40.50.70.5-0.5-0.5-0.8-0.7-0.90.9-0.8
Na content in liver1.11.22.60.61.51.31.5-1.41.6-0.7-1.4-1.3-1.30.80.00.3-0.00.0
Rb content in liver1.72.04.2-2.0-1.8-1.8-1.81.3-1.41.91.81.41.3-1.1-0.1-0.60.4-0.3
Se content in liver1.31.53.50.81.31.81.1-1.71.9-0.7-1.0-1.8-1.70.2-0.7-0.40.6-0.6
Sr content in liver6.65.713.03.63.12.63.3-2.11.3-3.4-3.2-1.9-1.62.40.81.6-1.11.0
Zn content in liver0.70.71.4-1.10.20.5-0.0-0.91.21.00.1-0.9-1.0-0.6-1.2-0.91.0-1.0
Bone: minimum diameter1.83.26.7-0.9-2.4-2.2-2.42.6-2.31.02.22.32.3-1.30.5-0.4-0.10.1
Time in familiar zone, hab. session 12.32.25.10.6-1.1-1.7-0.72.2-2.2-0.60.52.12.30.51.51.2-1.51.4
Time in novel zone, hab. session 11.11.12.9-0.61.01.11.0-1.71.70.3-0.9-1.5-1.60.4-0.5-0.30.5-0.4
Total zone transitions, hab. session 12.12.95.90.8-0.4-1.30.51.6-1.7-1.2-0.81.81.91.92.42.3-2.42.4
Total locomotion distance, hab. session 11.31.93.71.50.3-0.50.81.0-1.2-1.6-1.01.01.21.61.91.9-1.91.9
Locomotion velocity, hab. session 10.91.32.61.20.2-0.40.70.8-1.0-1.3-0.80.81.01.41.61.6-1.61.6
Time in familiar zone, hab. session 22.52.65.3-1.9-2.0-1.5-2.31.1-1.32.02.31.11.0-2.0-1.1-1.51.2-1.2
Time in novel zone, hab. session 21.21.22.50.91.31.11.6-1.01.2-1.0-1.6-1.0-1.01.30.60.8-0.60.6
Total zone transitions, hab. session 21.62.14.60.4-1.1-1.6-0.72.1-2.1-0.50.52.02.10.61.71.2-1.51.4
Total locomotion distance, hab. session 20.81.02.81.70.60.00.70.5-0.7-1.6-0.80.50.71.11.21.2-1.21.2
Locomotion velocity, hab. session 21.01.43.81.90.80.21.00.4-0.6-1.8-1.10.40.61.41.41.4-1.41.4
Novel to familiar place preference ratio0.00.00.10.40.10.2-0.10.1-0.0-0.10.2-0.1-0.0-0.2-0.1-0.30.2-0.2
Novelty place preference0.00.00.10.1-0.2-0.1-0.30.3-0.30.00.30.20.3-0.20.0-0.20.1-0.1
Time in novel zone, NPP test0.10.10.2-0.0-0.3-0.2-0.40.3-0.30.20.50.20.3-0.3-0.1-0.30.2-0.2
Total zone transitions, NPP test0.40.61.00.90.1-0.40.20.7-1.0-0.9-0.30.80.90.81.01.0-1.01.0
Total locomotion distance, NPP test0.20.31.11.10.3-0.00.10.3-0.7-0.9-0.10.30.50.30.50.4-0.40.4
Locomotion velocity, NPP test0.40.51.71.30.4-0.10.30.4-0.9-1.1-0.40.50.70.70.90.8-0.80.7
Intraocular pressure0.00.00.1-0.2-0.3-0.2-0.10.1-0.30.10.10.10.10.20.20.2-0.20.2
Delta distance traveled before/after self-admin1.21.32.71.31.41.61.3-1.41.4-1.2-1.3-1.5-1.40.6-0.20.10.2-0.2
Delta ambulatory time before/after self-admin0.91.22.51.31.61.41.4-1.21.2-1.2-1.3-1.2-1.10.7-0.10.30.0-0.1
Parametrial fat weight0.92.14.61.61.92.11.6-1.71.8-1.4-1.5-1.9-1.80.5-0.6-0.10.4-0.4
Pavlov. Cond. lever latency0.10.10.30.00.40.00.5-0.20.3-0.2-0.5-0.1-0.10.50.40.4-0.30.3
Pavlov. Cond. magazine entry latency0.50.71.40.50.51.20.3-0.91.1-0.3-0.2-1.2-1.2-0.5-1.0-0.70.9-0.9
Pavlov. Cond. change in total contacts0.10.10.30.60.40.50.4-0.30.3-0.5-0.3-0.4-0.30.1-0.10.10.0-0.1
Pavlov. Cond. index score0.10.20.50.50.30.70.2-0.40.5-0.4-0.2-0.6-0.6-0.1-0.4-0.20.2-0.2
Pavlov. Cond. latency score0.10.20.40.50.20.60.1-0.30.4-0.3-0.0-0.6-0.5-0.2-0.5-0.30.3-0.3
Pavlov. Cond. lever contacts0.30.40.9-0.4-0.6-0.0-0.80.1-0.10.60.9-0.1-0.1-1.0-0.8-0.90.8-0.8
Pavlov. Cond. magazine entry number0.20.30.6-0.4-0.3-0.8-0.10.5-0.60.30.00.70.70.40.70.5-0.60.6
Pavlov. Cond. intertrial magazine entries1.31.63.41.00.8-0.41.20.4-0.7-1.2-1.30.80.91.71.81.8-1.71.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.50.30.70.2-0.40.6-0.4-0.2-0.6-0.6-0.1-0.5-0.30.3-0.3
Pavlov. Cond. response bias0.40.41.1-0.2-0.10.5-0.4-0.40.40.30.5-0.6-0.6-0.9-1.1-0.91.0-1.0
Pavlov. Cond. lever latency0.60.93.5-1.9-1.3-1.3-0.80.8-0.61.50.70.90.7-0.20.20.1-0.20.3
Pavlov. Cond. magazine entry latency0.91.12.41.01.21.50.6-1.41.3-0.7-0.5-1.4-1.4-0.4-1.0-0.81.0-1.0
Pavlov. Cond. change in total contacts0.10.21.21.10.10.1-0.10.5-0.5-0.80.10.30.4-0.00.40.1-0.20.1
Pavlov. Cond. index score0.30.41.21.10.70.90.1-0.60.5-0.7-0.0-0.7-0.6-0.5-0.6-0.70.7-0.8
Pavlov. Cond. latency score0.60.81.81.31.11.30.5-1.00.9-0.9-0.4-1.1-1.0-0.3-0.7-0.60.7-0.8
Pavlov. Cond. lever contacts0.40.52.61.61.01.00.5-0.60.4-1.2-0.4-0.6-0.5-0.0-0.2-0.30.3-0.4
Pavlov. Cond. magazine entry number0.50.61.4-0.8-0.9-1.2-0.51.0-0.90.60.41.11.00.30.70.6-0.70.7
Pavlov. Cond. intertrial magazine entries1.92.96.1-1.5-2.1-2.5-1.72.2-2.21.31.52.42.3-0.21.00.4-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.30.51.21.10.81.00.3-0.60.5-0.8-0.1-0.8-0.7-0.4-0.6-0.60.6-0.7
Pavlov. Cond. response bias0.10.21.01.00.30.4-0.2-0.0-0.2-0.60.3-0.10.0-0.4-0.3-0.50.4-0.5
Time in closed arm before self-admin0.50.61.4-0.6-1.2-1.0-1.01.0-1.10.60.91.01.0-0.50.2-0.1-0.10.1
Time in closed arm after self-admin0.20.20.5-0.7-0.1-0.3-0.4-0.0-0.10.60.40.20.1-0.7-0.4-0.40.5-0.5
Time in open arm before self-admin1.61.74.71.42.21.61.8-1.51.4-1.3-1.7-1.3-1.30.9-0.00.4-0.10.0
Time in open arm after self-admin0.20.20.50.70.40.50.5-0.20.3-0.7-0.5-0.3-0.20.50.30.4-0.30.3
Bone: periosteal estimation1.43.05.9-1.3-2.4-2.1-2.42.3-2.01.32.32.02.0-1.50.1-0.70.2-0.2
Bone: periosteal perimeter1.22.04.1-1.0-2.0-1.8-1.82.0-1.71.01.71.81.8-0.90.4-0.2-0.20.2
Bone: post-yield work2.03.06.0-2.1-2.4-1.8-2.51.6-1.62.12.41.51.3-1.8-0.6-1.20.8-0.8
Progressive ratio test 1 active lever presses0.30.41.30.10.1-0.9-0.10.8-1.1-0.10.11.11.10.20.60.5-0.50.5
Progressive ratio test 1 breakpoint0.30.41.30.10.2-0.9-0.10.8-1.1-0.10.01.11.10.20.60.5-0.50.4
Progressive ratio test 1 inactive lever presses1.42.04.3-1.7-1.6-2.1-1.61.6-1.71.51.61.81.7-0.90.0-0.30.1-0.1
Progressive ratio test 2 active lever presses0.70.92.7-1.6-0.4-0.8-0.90.0-0.31.51.00.40.3-1.1-0.9-1.01.0-1.0
Progressive ratio test 2 breakpoint0.91.03.2-1.8-0.5-0.9-1.00.1-0.31.71.10.50.3-1.2-0.9-1.01.0-1.0
Progressive ratio test 2 inactive lever presses1.62.75.4-2.0-1.8-2.3-1.91.8-2.01.81.92.11.9-1.10.0-0.40.2-0.2
Incentive Sensitization - Responses1.62.26.4-2.5-1.5-1.4-1.80.5-0.62.41.90.80.6-1.7-1.1-1.41.2-1.2
Incentive Sensitization - Breakpoint1.52.05.8-2.4-1.3-1.1-1.70.3-0.42.31.70.50.3-1.6-1.1-1.41.3-1.2
Sum of active levers in priming session hrs 5-60.30.30.60.8-0.70.1-0.00.6-0.1-0.7-0.10.20.20.40.60.6-0.60.7
Progressive ratio0.30.41.31.10.30.10.50.5-0.3-1.0-0.50.20.30.70.90.8-0.80.8
Food seeking constrained by brief footshock8.19.928.05.31.40.12.31.8-2.0-4.9-2.61.52.13.33.83.9-3.83.7
Seeking ratio, punishment vs. effort0.60.81.51.0-0.3-0.6-0.01.1-1.2-1.0-0.11.11.20.61.11.0-1.11.0
Retroperitoneal fat weight2.29.322.01.12.84.42.1-4.14.7-0.8-1.8-4.7-4.7-0.3-2.7-1.82.2-2.2
Reaction time number correct0.40.83.51.41.90.81.2-1.00.2-1.2-1.1-0.5-0.40.4-0.20.30.1-0.2
Reaction time mean minus median0.10.20.4-0.6-0.4-0.1-0.5-0.10.10.60.5-0.1-0.1-0.5-0.6-0.40.4-0.4
Reaction time mean minus median AUC0.10.30.7-0.8-0.3-0.0-0.4-0.40.20.80.4-0.2-0.3-0.6-0.8-0.60.6-0.6
Reaction time num false alarms0.10.20.60.2-0.7-0.1-0.20.8-0.3-0.20.10.20.20.10.50.3-0.50.6
Reaction time num false alarms AUC0.40.61.31.10.00.20.60.5-0.3-1.1-0.70.10.20.91.01.1-1.11.1
Reaction time trials correct on left0.40.83.51.41.90.81.2-1.00.2-1.2-1.1-0.5-0.40.4-0.20.30.1-0.2
Reaction time trials on left0.40.83.51.41.90.81.2-1.00.2-1.2-1.1-0.5-0.40.4-0.20.30.1-0.2
Reaction time mean0.91.44.4-2.1-1.7-1.1-1.50.6-0.61.91.50.70.5-1.1-0.7-0.80.6-0.6
Reaction time mean AUC0.61.03.6-1.9-1.2-0.7-1.20.1-0.11.71.20.2-0.0-1.0-0.9-0.90.8-0.8
Median of all reaction times0.91.34.5-2.1-1.5-1.1-1.40.5-0.51.91.40.60.4-1.0-0.6-0.80.7-0.6
Reaction time omissions0.30.40.90.60.1-0.10.50.3-0.4-0.7-0.60.30.41.00.90.9-0.90.9
Reaction time false alarm rate0.40.51.40.3-0.9-0.2-0.01.0-0.4-0.4-0.10.30.40.61.10.9-1.11.2
Reaction time premature initiation rate0.00.00.1-0.1-0.10.0-0.2-0.2-0.00.10.2-0.1-0.1-0.4-0.4-0.20.3-0.3
Reaction time premature initiations0.10.30.70.60.90.60.4-0.80.2-0.4-0.3-0.5-0.4-0.3-0.6-0.30.5-0.6
Std. dev. reaction times0.40.71.8-1.3-1.3-0.8-1.10.5-0.41.21.10.50.3-0.7-0.5-0.50.4-0.3
Reaction time trials completed0.40.83.51.41.90.81.2-1.00.2-1.2-1.1-0.5-0.40.4-0.20.30.1-0.2
Reaction time trials AUC0.40.73.01.21.70.81.0-1.00.2-1.0-0.9-0.6-0.50.2-0.40.00.3-0.4
Run reversals in cocaine runway, females0.40.41.0-1.0-0.7-0.4-0.80.1-0.11.00.80.20.1-0.7-0.5-0.60.6-0.5
Run reversals in cocaine runway, males0.10.10.5-0.70.0-0.2-0.2-0.3-0.00.60.20.0-0.0-0.4-0.4-0.40.5-0.4
Latency to leave start box in cocaine runway0.40.41.3-0.7-1.1-0.8-0.81.0-0.70.60.70.70.7-0.20.20.0-0.20.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.1-0.5-0.2-0.30.4-0.20.10.30.20.2-0.00.10.0-0.20.2
Latency to leave start box in cocaine runway, M1.21.12.5-1.4-1.6-1.4-1.31.2-1.11.21.21.21.1-0.60.1-0.2-0.00.1
Std. dev. time between licks in bursts1.41.94.41.50.90.01.30.3-0.5-1.6-1.40.50.62.11.91.9-1.91.8
Total sessions with >9 infusions0.70.81.7-1.1-0.9-1.3-1.10.9-1.11.01.01.21.1-0.7-0.1-0.30.1-0.2
Short access day 1 total inactive lever presses1.31.74.6-2.1-1.4-1.2-1.60.5-0.52.01.70.70.5-1.5-0.9-1.21.0-1.0
Short access day 10 total inactive lever presses0.10.20.8-0.4-0.9-0.6-0.60.6-0.60.40.60.50.5-0.20.10.0-0.10.2
Short access day 1 total infusions0.10.20.5-0.7-0.1-0.3-0.4-0.1-0.00.70.40.10.0-0.6-0.5-0.50.5-0.5
Short access day 10 total infusions0.00.10.1-0.30.30.00.1-0.30.20.2-0.0-0.1-0.1-0.2-0.4-0.20.3-0.3
Short access total infusions0.10.10.3-0.20.50.20.1-0.40.30.2-0.1-0.2-0.3-0.3-0.5-0.30.4-0.5
Short access day 1 locomotion1.11.34.3-2.1-0.9-0.9-1.30.1-0.21.91.30.40.2-1.3-1.1-1.21.1-1.1
Short access day 10 total locomotion0.61.22.7-0.0-1.1-1.4-0.71.6-1.6-0.00.61.61.60.21.00.7-1.01.0
Short access total locomotion0.50.61.30.7-0.1-0.70.11.0-1.1-0.7-0.21.01.10.60.90.9-1.00.9
One hour access (0.3 mA shock)3.03.46.6-2.6-2.2-2.4-2.31.7-1.92.32.32.01.8-1.5-0.3-0.80.5-0.5
Compulsive drug intake1.51.83.2-1.7-1.7-1.8-1.71.4-1.61.51.61.51.4-1.00.0-0.50.2-0.2
One hour access (shock baseline)0.60.92.9-1.7-0.5-0.5-0.9-0.20.11.60.90.1-0.1-1.1-1.1-1.01.0-1.0
Social response proportion1.61.84.8-2.2-1.7-1.1-1.70.6-0.32.11.80.50.4-1.6-1.0-1.31.0-1.0
Social responses2.63.46.9-2.6-2.6-2.2-2.41.7-1.72.42.41.71.5-1.6-0.3-1.00.5-0.5
Social time2.63.58.00.2-1.8-2.2-1.12.8-2.8-0.30.92.62.70.52.01.4-1.81.8
Soleus weight0.00.10.40.3-0.6-0.1-0.60.5-0.2-0.10.60.20.2-0.6-0.2-0.40.2-0.2
Bone: stiffness1.52.55.2-1.3-2.3-2.0-2.12.1-1.81.22.01.91.9-1.20.2-0.40.00.0
Tibialis anterior weight0.72.34.41.11.12.10.2-1.61.9-0.50.0-2.0-1.9-1.2-1.9-1.71.8-1.8
Time to tail flick, vehicle, before self-admin0.30.30.80.7-0.1-0.4-0.00.7-0.9-0.6-0.00.60.70.20.70.6-0.60.6
Time to tail flick, vehicle, after self-admin0.81.13.2-1.8-1.8-0.8-1.40.5-0.21.61.40.30.2-1.1-0.7-0.80.6-0.5
Time to tail flick, test, before self-admin1.92.05.32.31.00.01.20.7-0.7-2.2-1.30.70.91.51.71.7-1.71.6
Time to tail flick, test, after self-admin0.10.10.40.20.20.50.2-0.50.6-0.1-0.2-0.6-0.6-0.2-0.3-0.20.3-0.3
Delta time to tail flick, vehicle, before/after SA0.70.62.3-1.5-0.7-0.2-0.7-0.30.61.30.7-0.3-0.4-0.6-0.9-0.90.8-0.7
Delta time to tail flick, test, before/after SA1.01.12.7-1.7-0.8-0.0-0.9-0.50.51.61.0-0.5-0.7-1.2-1.2-1.21.2-1.1
Tibia length1.84.98.8-1.8-2.8-3.0-2.82.8-2.71.82.72.92.8-1.70.3-0.60.1-0.1
Ambulatory time before self-admin1.82.75.61.2-1.3-1.3-0.52.4-2.1-1.20.31.92.10.82.11.5-1.92.0
Ambulatory time after self-admin2.12.46.42.5-0.2-0.00.61.4-1.1-2.3-0.80.81.11.62.11.8-2.02.0
Bone: tissue strength1.01.02.51.60.2-0.20.50.8-0.9-1.5-0.60.70.91.01.21.2-1.21.2
Total heroin consumption0.10.10.40.6-0.20.30.20.10.1-0.5-0.2-0.1-0.10.60.40.3-0.40.4
Bone: trabecular number0.20.31.11.00.70.60.7-0.30.3-1.0-0.7-0.3-0.20.60.30.5-0.40.4
Bone: trabecular spacing0.10.10.3-0.1-0.00.1-0.3-0.10.10.30.3-0.1-0.1-0.4-0.3-0.50.4-0.4
Bone: trabecular thickness0.10.20.3-0.5-0.4-0.1-0.50.10.10.50.5-0.0-0.1-0.6-0.5-0.50.4-0.4
Bone: trabecular tissue density0.81.22.5-0.80.71.00.3-1.61.50.8-0.2-1.5-1.6-0.5-1.3-1.01.2-1.2
Water consumed over 24 hours0.50.61.60.2-0.6-0.9-0.41.2-1.3-0.30.31.11.20.10.80.6-0.70.7
Number of responses in last shaping day1.11.23.5-1.9-0.9-0.4-1.1-0.30.31.71.1-0.2-0.3-1.2-1.3-1.21.2-1.1