Hub : Genes

Usp48

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Eye	mRNA stability	Usp48	0.5	0.17	3.6e-05	0.1	0.18	0.16	0.15	1.2e-02	1.0e-03	2.1e-03	2.6e-03
2	Eye	gene expression	Usp48	0.65	0.15	1.0e-06	0.01	0.13	0.12	0.11	2.2e-01	5.5e-03	6.7e-03	9.6e-03
3	PL	gene expression	Usp48	0.1	0.06	2.6e-14	0.13	0.12	0.13	0.13	6.5e-14	5.6e-13	7.3e-14	8.5e-14
4	BLA	gene expression	Usp48	0.07	0.06	2.1e-03	0.03	0.02	0.01	0.03	6.7e-03	1.8e-02	4.9e-02	1.6e-02
5	IL	gene expression	Usp48	0.15	0.1	9.8e-04	0.18	0.16	0.14	0.18	4.2e-05	1.4e-04	2.8e-04	4.7e-05
6	Adipose	intron excision ratio	chr5_149800971_149810309	0.04	0.03	2.7e-04	0	0.02	0.01	0.01	1.1e-01	2.6e-03	9.8e-03	3.1e-02
7	Adipose	intron excision ratio	chr5_149810429_149811690	0.05	0.04	2.0e-04	0.02	0.02	0.02	0.01	4.4e-03	1.5e-03	5.3e-03	1.7e-02
8	Liver	alternative TSS	XM_006239234.4	0.03	0.02	3.5e-04	0.02	0.02	0.02	0.03	1.1e-03	1.2e-03	6.0e-03	8.3e-04
9	Brain	gene expression	Usp48	0.07	0.04	2.6e-08	0.07	0.09	0.08	0.07	1.8e-07	1.7e-08	1.2e-07	1.6e-07
10	Liver	alternative TSS	NM_198785.2	0.02	0.02	1.3e-03	0.02	0.01	0.01	0.02	9.0e-04	9.9e-03	1.7e-02	2.1e-03
11	Liver	alternative TSS	NM_198785.2	0.02	0.02	6.8e-03	0.01	0.01	0.01	0.01	9.7e-03	1.9e-02	5.2e-02	1.3e-02
12	Adipose	gene expression	Usp48	0.06	0.04	9.5e-05	0.04	0.03	0.02	0.04	2.6e-05	9.3e-05	1.1e-03	8.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	0.1	0.2	0.5	-0.2	0.0	0.4	0.3	0.2	-0.3	0.4	0.6	-0.3	0.7	0.7	-0.5
Area under the delay curve	0.5	0.5	0.7	0.7	-0.8	0.8	0.7	0.5	0.8	-0.8	0.7	-0.9	0.7	0.7	0.7
BMI with tail	0.1	0.3	2.5	-0.6	0.2	-0.2	-0.3	-0.6	0.3	-0.3	-0.2	-0.5	-0.1	-0.1	1.6
BMI without tail	0.4	0.8	1.3	-0.9	0.8	-0.8	-0.9	-1.0	-0.8	0.7	-1.0	0.6	-1.1	-1.1	-0.1
Body weight	1.9	8.0	11.4	-3.3	3.1	-3.0	-2.9	-3.4	-3.1	3.1	-2.6	2.7	-2.3	-2.3	-1.5
Weight adjusted by age	1.0	1.1	2.1	-0.7	0.9	-1.1	-1.4	-1.1	-0.5	0.5	-1.3	1.1	-1.4	-1.4	-0.1
Bone surface	0.1	0.1	0.4	-0.4	0.3	0.2	0.1	-0.2	-0.6	0.6	0.1	0.0	-0.0	-0.0	-0.6
Bone volume	0.1	0.2	1.1	-0.2	0.2	0.3	0.2	0.1	-0.6	0.6	0.4	0.0	0.4	0.4	-1.0
Breakpoint value in progressive ratio session	1.1	1.2	1.9	-1.3	1.3	-1.4	-1.3	-1.1	-1.1	1.1	-1.1	1.1	-0.9	-0.9	-0.2
Number of licking bursts	0.0	0.0	0.1	0.0	0.0	-0.2	-0.1	0.2	0.2	-0.2	-0.2	0.1	-0.2	-0.2	0.3
Context. condit. distance diff. score	0.6	0.7	1.6	-1.3	1.0	-1.0	-1.0	-0.9	-1.0	0.9	-0.7	0.7	-0.5	-0.5	-0.1
Locomotion velocity, session 1	1.3	1.4	2.4	0.9	-1.2	1.5	1.5	1.3	0.9	-0.9	1.4	-1.5	1.2	1.2	0.5
Locomotion distance, session 1	1.7	2.2	3.4	1.2	-1.5	1.8	1.8	1.7	1.3	-1.2	1.6	-1.8	1.4	1.4	0.8
Locomotion velocity, session 2	3.2	3.8	5.9	2.4	-2.2	2.3	2.3	2.4	1.9	-1.8	1.8	-1.8	1.5	1.5	0.3
Locomotion distance, session 2	0.5	0.7	1.8	0.7	-0.9	1.3	1.3	1.1	0.4	-0.3	0.9	-1.0	0.6	0.6	-0.3
Locomotion velocity, session 3	1.6	1.9	3.2	1.0	-1.3	1.2	1.2	1.6	1.5	-1.6	1.2	-1.6	1.2	1.2	1.8
Locomotion distance, session 3	0.5	0.5	1.7	-1.3	0.9	-0.8	-0.7	-0.6	-0.8	0.8	-0.7	0.3	-0.5	-0.5	0.2
Stereotopy head waving bouts, day 3	1.0	1.2	2.5	1.6	-1.3	1.4	1.4	0.8	1.0	-1.0	1.1	-0.9	0.9	0.9	-0.2
Stereotopy head waving duration, day 3	0.6	0.7	2.1	1.4	-1.1	1.0	0.9	0.4	0.9	-0.9	0.7	-0.5	0.5	0.5	-0.1
Locomotion velocity, session 7	2.0	2.2	3.6	-1.9	1.7	-1.7	-1.7	-1.4	-1.6	1.6	-1.4	1.4	-1.3	-1.3	-0.4
Locomotion distance, session 7	0.3	0.3	0.5	-0.7	0.7	-0.7	-0.7	-0.6	-0.7	0.7	-0.4	0.6	-0.2	-0.2	-0.6
Stereotopy head waving bouts, day 7	0.2	0.2	0.7	-0.1	0.1	-0.1	-0.1	-0.5	0.0	-0.1	-0.6	0.1	-0.8	-0.8	0.6
Stereotopy head waving duration, day 7	0.2	0.2	0.8	-0.1	0.3	-0.2	-0.2	-0.5	-0.3	0.3	-0.7	0.4	-0.9	-0.9	-0.1
Locomotion velocity, session 8	0.7	0.9	1.5	0.9	-1.1	1.2	1.0	1.2	1.0	-1.0	0.6	-1.2	0.3	0.3	1.0
Locomotion distance, session 8	0.1	0.1	0.5	-0.7	0.3	0.0	-0.0	-0.1	-0.3	0.3	0.0	-0.4	0.0	0.0	0.4
Degree of sensitization distance	0.5	0.5	1.4	1.2	-0.8	0.6	0.5	0.5	0.7	-0.6	0.8	-0.1	0.8	0.8	-0.7
Degree of sensitization stereotypy	1.3	1.5	2.3	-1.2	1.2	-1.2	-1.2	-1.3	-1.0	1.0	-1.5	1.1	-1.5	-1.5	-0.1
Conditioned locomotion	1.9	2.2	2.7	1.6	-1.6	1.4	1.3	1.5	1.7	-1.6	1.5	-1.4	1.5	1.5	0.8
Cocaine response after cond. corrected	0.4	0.5	1.1	0.9	-0.6	0.2	0.2	0.2	1.0	-1.0	0.6	-0.3	0.7	0.7	0.8
Cocaine response after cond. not corrected	0.1	0.1	0.3	0.4	-0.2	-0.2	-0.1	-0.2	0.5	-0.6	0.1	0.1	0.2	0.2	0.6
Cocaine response before conditioning	1.6	2.0	2.7	-1.4	1.4	-1.3	-1.1	-1.2	-1.6	1.7	-1.5	1.4	-1.5	-1.5	-1.0
Saline control response	0.2	0.2	1.2	0.1	-0.3	0.2	0.1	0.2	0.5	-0.6	0.1	-0.5	0.1	0.1	1.1
Bone: connectivity density	0.1	0.2	0.5	-0.6	0.5	-0.2	-0.3	-0.3	-0.7	0.7	-0.3	0.3	-0.3	-0.3	-0.4
Bone: cortical apparent density	1.8	2.4	3.6	-1.6	1.7	-1.9	-1.9	-1.5	-1.5	1.4	-1.6	1.8	-1.3	-1.3	-1.0
Bone: cortical area	1.1	1.6	3.5	-1.6	1.5	-0.9	-1.1	-1.1	-1.8	1.9	-0.7	1.2	-0.4	-0.4	-1.5
Bone: cortical porosity	0.6	0.6	1.3	1.1	-0.9	1.0	1.0	0.9	0.5	-0.4	0.8	-0.4	0.7	0.7	-0.6
Bone: cortical porosity	1.3	1.4	2.9	1.7	-1.4	1.4	1.4	1.2	1.0	-1.0	1.2	-0.8	1.0	1.0	-0.5
Bone: cortical thickness	0.6	0.9	2.1	-1.5	1.2	-0.9	-1.0	-0.9	-1.3	1.3	-0.7	0.8	-0.4	-0.4	-0.4
Bone: cortical thickness	0.3	0.3	0.7	-0.1	-0.2	0.3	0.3	0.8	0.3	-0.3	0.6	-0.7	0.9	0.9	0.4
Bone: cortical tissue density	1.6	2.1	3.3	-1.4	1.6	-1.8	-1.8	-1.4	-1.3	1.3	-1.5	1.7	-1.2	-1.2	-0.9
Condit. Reinf. active minus inactive responses	0.3	0.4	0.9	1.0	-0.6	0.6	0.7	0.5	0.4	-0.4	0.7	-0.1	0.6	0.6	-0.7
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.6	0.8	-0.4	0.3	0.3	0.4	0.2	-0.2	0.4	0.2	0.5	0.5	-0.8
Condit. Reinf. active responses	0.3	0.4	3.3	0.7	-0.3	0.6	0.7	0.3	-0.2	0.3	0.3	0.2	0.1	0.1	-1.8
Condit. Reinf. inactive responses	0.4	0.5	3.6	0.1	0.1	0.4	0.6	0.0	-0.7	0.8	-0.2	0.2	-0.4	-0.4	-1.9
Incentive salience index mean	0.4	0.4	2.7	0.7	-0.3	0.5	0.6	0.6	-0.2	0.3	0.6	0.2	0.6	0.6	-1.6
Condit. Reinf. lever presses	0.5	0.7	5.1	-0.0	0.3	0.2	0.3	0.4	-0.9	1.0	0.3	0.6	0.3	0.3	-2.3
Condit. Reinf. active minus inactive responses	0.1	0.1	0.4	0.1	-0.4	0.4	0.4	0.5	0.4	-0.4	0.3	-0.7	0.2	0.2	0.4
Condit. Reinf. active-inactive response ratio	1.0	1.0	1.9	1.2	-1.2	1.0	0.9	0.9	1.3	-1.4	0.8	-1.1	0.7	0.7	0.6
Condit. Reinf. active responses	0.2	0.2	0.7	-0.9	0.5	-0.2	-0.2	0.1	-0.8	0.8	-0.3	0.1	-0.3	-0.3	-0.4
Condit. Reinf. inactive responses	1.9	2.3	5.4	-1.9	1.7	-1.1	-1.0	-0.7	-2.3	2.3	-1.1	1.3	-1.1	-1.1	-1.6
Condit. Reinf. lever presses	0.3	0.4	0.9	0.1	-0.3	0.9	0.9	0.9	-0.3	0.4	0.5	-0.6	0.2	0.2	-0.9
Condit. Reinf. lever reinforcers received	0.2	0.3	0.8	-0.8	0.5	-0.1	-0.1	0.0	-0.9	0.9	-0.3	0.1	-0.4	-0.4	-0.8
Conditioned reinforcement - actives	0.4	0.4	0.8	-0.5	0.6	-0.5	-0.5	-0.5	-0.8	0.8	-0.5	0.7	-0.6	-0.6	-0.9
Conditioned reinforcement - inactives	0.3	0.3	0.5	-0.7	0.6	-0.4	-0.4	-0.7	-0.7	0.7	-0.5	0.4	-0.5	-0.5	-0.5
Conditioned locomotion	1.2	1.4	1.7	-1.2	1.3	-1.1	-1.2	-1.1	-1.3	1.3	-1.1	1.2	-1.1	-1.1	-1.2
Patch foraging indifference point 0 sec	0.2	0.3	1.0	-0.7	0.5	-0.1	-0.3	-0.2	-0.6	0.6	-0.8	0.1	-1.0	-1.0	0.1
Patch foraging indifference point AUC	1.1	1.2	2.5	-1.6	1.4	-1.3	-1.4	-0.8	-1.2	1.2	-1.0	0.9	-0.8	-0.8	0.1
Delay disc. indifference point, 0s delay	1.2	1.3	2.1	0.9	-1.2	1.2	1.3	0.9	1.1	-1.1	1.3	-1.5	1.2	1.2	1.0
Delay disc. indifference point, 16s delay	0.0	0.0	0.0	0.0	-0.0	0.2	-0.0	0.0	0.0	-0.0	0.1	-0.0	0.1	0.1	-0.1
Delay disc. indifference point, 2s delay	0.3	0.3	0.6	0.5	-0.6	0.5	0.6	0.3	0.7	-0.7	0.5	-0.7	0.5	0.5	0.7
Delay disc. indifference point, 24s delay	0.0	0.0	0.1	0.4	-0.1	0.2	0.1	0.3	0.0	-0.0	0.2	0.1	0.1	0.1	-0.4
Delay disc. indifference point, 4s delay	0.5	0.5	0.7	0.8	-0.8	0.9	0.8	0.1	0.7	-0.7	0.7	-0.8	0.7	0.7	0.6
Delay disc. indifference point, 8s delay	0.4	0.4	0.8	0.5	-0.7	0.7	0.5	0.6	0.8	-0.8	0.5	-0.9	0.4	0.4	0.9
Indifference point function ln k	3.4	4.8	8.1	2.8	-2.6	2.8	2.5	2.3	2.1	-2.0	2.2	-2.1	1.6	1.6	-0.2
Indifference point function log k	3.4	4.8	8.1	2.8	-2.6	2.8	2.5	2.3	2.1	-2.0	2.2	-2.1	1.6	1.6	-0.2
Patch foraging total patch changes 0 sec	0.1	0.2	0.6	-0.5	0.3	0.2	-0.1	0.1	-0.4	0.4	-0.6	-0.1	-0.8	-0.8	0.1
Patch foraging total patch changes 12 sec	2.0	2.6	3.5	-1.9	1.7	-1.4	-1.6	-1.4	-1.8	1.8	-1.7	1.5	-1.7	-1.7	-0.8
Patch foraging total patch changes 18 sec	1.2	1.6	2.6	-1.6	1.4	-1.1	-1.2	-1.0	-1.5	1.5	-1.2	1.1	-1.1	-1.1	-0.5
Patch foraging total patch changes 24 sec	1.1	1.3	2.9	-1.7	1.3	-1.0	-1.2	-1.1	-1.0	0.9	-1.3	0.6	-1.3	-1.3	0.9
Patch foraging total patch changes 6 sec	3.0	4.4	6.9	-2.6	2.2	-1.9	-2.3	-2.1	-2.0	1.9	-2.4	1.6	-2.4	-2.4	0.1
Patch foraging time to switch 0 sec	1.0	1.5	2.2	-1.0	1.2	-1.4	-1.3	-1.5	-1.1	1.1	-1.3	1.4	-1.2	-1.2	-0.6
Patch foraging water rate 0 sec	1.7	2.8	3.7	1.6	-1.8	1.8	1.7	1.7	1.8	-1.8	1.6	-1.9	1.5	1.5	1.2
Patch foraging water rate 12 sec	1.7	2.5	4.1	1.2	-1.6	1.8	1.6	1.8	1.6	-1.6	1.5	-2.0	1.4	1.4	1.4
Patch foraging water rate 18 sec	0.9	1.2	2.6	1.1	-1.0	1.6	1.5	1.4	0.3	-0.2	1.1	-0.8	0.9	0.9	-1.2
Patch foraging water rate 24 sec	1.9	2.6	4.2	2.1	-1.9	2.0	2.0	1.6	1.6	-1.5	1.5	-1.6	1.1	1.1	0.2
Patch foraging water rate 6 sec	2.8	4.0	5.3	2.1	-2.3	2.3	2.2	2.2	2.2	-2.2	1.8	-2.3	1.5	1.5	1.3
Seeking ratio, delayed vs. immediate footshock	0.3	0.3	1.9	-0.2	-0.2	0.2	0.3	-0.0	0.4	-0.5	0.4	-0.8	0.4	0.4	1.4
Distance traveled before self-admin	6.1	6.4	9.7	-3.1	3.0	-3.0	-2.6	-2.4	-2.8	2.7	-2.5	2.6	-2.1	-2.1	-0.7
Distance traveled after self-admin	2.5	2.8	4.9	-2.2	2.0	-1.8	-1.5	-1.7	-2.0	2.0	-1.4	1.6	-1.1	-1.1	-0.9
Extensor digitorum longus weight	0.2	0.7	1.4	0.2	-0.7	1.0	0.9	0.8	0.5	-0.5	1.0	-1.2	0.9	0.9	1.2
Bone: elastic displacement	0.0	0.0	0.1	-0.1	-0.0	0.2	0.3	-0.0	-0.2	0.2	0.3	-0.2	0.2	0.2	-0.1
Bone: elastic work	0.0	0.1	0.2	-0.5	0.2	-0.1	-0.0	-0.1	-0.3	0.3	0.2	-0.1	0.3	0.3	0.2
Bone: endosteal estimation	0.7	1.4	5.7	-0.9	1.1	-0.7	-0.7	-0.8	-1.7	1.8	-0.3	1.3	-0.3	-0.3	-2.4
Bone: endosteal perimeter	0.2	0.5	2.3	0.1	-0.0	0.7	0.5	0.2	-0.6	0.7	0.8	0.0	0.8	0.8	-1.5
Epididymis fat weight	0.1	0.2	0.6	0.1	-0.1	-0.0	0.2	-0.1	0.2	-0.2	0.6	-0.2	0.8	0.8	-0.2
Delta time in closed arm before/after self-admin	0.3	0.3	2.3	0.5	-0.1	0.3	0.1	0.1	-0.3	0.3	-0.1	0.3	-0.3	-0.3	-1.5
Delta time in open arm before/after self-admin	0.1	0.1	0.5	-0.2	0.3	-0.4	-0.1	-0.7	-0.2	0.2	-0.2	0.4	-0.1	-0.1	-0.1
Diff in mean of infusions in LGA sessions	0.0	0.1	0.2	0.1	0.0	0.1	0.1	-0.0	-0.1	0.2	0.3	0.1	0.4	0.4	-0.5
Delay discount exponential model param	0.4	0.4	0.5	-0.7	0.7	-0.7	-0.6	-0.4	-0.7	0.7	-0.6	0.7	-0.6	-0.6	-0.6
Extinction: sum of active levers before priming	0.5	0.5	0.9	-0.9	0.9	-0.8	-0.6	-1.0	-0.9	1.0	-0.5	0.8	-0.3	-0.3	-0.3
Active lever presses in extinction session 6	0.2	0.2	0.4	-0.3	0.5	-0.5	-0.4	-0.7	-0.5	0.5	-0.2	0.7	-0.0	-0.0	-0.5
Bone: final force	1.3	2.2	3.8	-1.9	1.8	-1.4	-1.6	-1.2	-1.9	1.9	-1.1	1.4	-0.9	-0.9	-1.1
Bone: final moment	1.0	1.7	3.2	-1.8	1.6	-1.2	-1.3	-1.0	-1.7	1.7	-1.0	1.2	-0.8	-0.8	-1.0
Food consumed during 24 hour testing period	0.9	1.0	1.8	-0.9	1.0	-1.1	-1.2	-1.3	-0.8	0.8	-1.1	1.1	-1.1	-1.1	-0.1
Glucose	2.4	3.6	5.9	-1.8	1.9	-2.4	-2.4	-2.4	-1.2	1.1	-2.2	2.0	-2.0	-2.0	0.3
Heart weight	1.2	1.8	3.5	-1.4	1.3	-1.7	-1.5	-1.9	-0.9	0.8	-1.5	1.1	-1.3	-1.3	0.5
Delay discount hyperbolic model param	0.5	0.5	0.7	-0.7	0.8	-0.8	-0.7	-0.4	-0.8	0.8	-0.7	0.8	-0.7	-0.7	-0.7
Intermittent access intake day 1-15 change	0.4	0.4	0.7	0.2	-0.3	0.7	0.9	0.7	-0.1	0.1	0.8	-0.5	0.9	0.9	-0.3
Intermittent access intake escalation	0.4	0.4	1.0	0.2	-0.2	0.6	0.8	0.6	-0.3	0.3	0.9	-0.2	1.0	1.0	-1.0
Intermittent access intake escalation 2	0.4	0.4	1.0	0.4	-0.3	0.6	0.8	0.7	-0.2	0.3	0.8	-0.1	0.9	0.9	-1.0
Intermitt. access day 1 inactive lever presses	4.0	4.3	5.8	-2.4	2.3	-2.0	-2.3	-1.9	-2.4	2.4	-1.9	2.1	-1.8	-1.8	-1.2
Intermitt. access day 15 inactive lever presses	1.7	1.8	2.8	-1.6	1.6	-1.4	-1.4	-1.0	-1.7	1.7	-1.2	1.5	-0.9	-0.9	-1.1
Intermitt. access escalation Index	0.2	0.2	1.2	-0.8	0.4	-0.4	-0.1	-0.3	-0.1	0.1	-0.3	-0.2	-0.2	-0.2	1.1
Intermittent access day 1 total infusions	4.9	5.7	7.6	-2.6	2.5	-2.5	-2.7	-2.5	-2.1	2.1	-2.7	2.2	-2.7	-2.7	-0.5
Intermittent access day 15 total infusions	2.5	2.8	4.0	-2.0	1.9	-1.7	-1.6	-1.5	-2.0	2.0	-1.5	1.7	-1.4	-1.4	-1.1
Intermittent access terminal intake (last 3 days)	1.8	2.0	3.3	-1.6	1.6	-1.4	-1.3	-1.1	-1.8	1.8	-1.2	1.5	-1.0	-1.0	-1.2
Intermittent access total infusions	2.8	3.1	4.1	-2.0	2.0	-1.9	-1.8	-1.6	-1.9	1.9	-1.7	1.8	-1.6	-1.6	-0.9
Intermittent access day 1 locomotion	0.2	0.2	0.5	-0.4	0.2	-0.2	-0.5	-0.4	0.1	-0.1	-0.5	-0.2	-0.7	-0.7	0.6
Intermittent access day 15 total locomotion	0.1	0.1	0.6	0.3	-0.2	0.4	0.4	0.0	0.1	-0.0	0.4	-0.2	0.4	0.4	-0.8
Intermittent access total locomotion	0.2	0.3	0.5	-0.7	0.5	-0.4	-0.4	-0.4	-0.5	0.4	-0.6	0.2	-0.7	-0.7	-0.3
Intermittent access standard deviation	1.5	1.6	2.7	-1.5	1.4	-1.1	-1.2	-1.4	-1.6	1.6	-0.9	1.2	-0.7	-0.7	-1.1
Left kidney weight	8.8	24.8	35.6	-5.3	5.3	-5.3	-5.3	-6.0	-5.1	5.0	-4.9	5.0	-4.6	-4.6	-2.5
Right kidney weight	4.6	12.9	19.1	-3.6	3.8	-3.8	-3.7	-4.4	-3.6	3.5	-3.7	3.7	-3.4	-3.4	-2.2
Cocaine induced anxiety	0.3	0.4	2.8	0.1	0.3	-0.2	-0.2	-0.2	-0.6	0.7	-0.1	0.8	-0.0	-0.0	-1.7
Post-drug Anxiety	1.7	1.9	2.5	1.6	-1.4	1.5	1.6	1.5	1.1	-1.1	1.6	-1.1	1.6	1.6	-0.3
Baseline Anxiety	3.9	4.2	6.3	1.6	-2.0	1.9	2.0	1.9	2.2	-2.2	1.9	-2.5	1.9	1.9	2.4
Tail length	2.1	6.4	10.1	-2.0	2.5	-2.3	-2.2	-2.5	-2.9	3.0	-2.2	3.0	-2.2	-2.2	-3.2
Length with tail	2.8	10.1	12.8	-3.1	3.4	-3.4	-3.0	-3.4	-3.6	3.6	-2.9	3.6	-2.6	-2.6	-2.8
Length without tail	1.2	2.6	4.2	-2.1	1.9	-1.9	-1.6	-2.0	-1.8	1.8	-1.4	1.6	-1.1	-1.1	-0.6
Times rat made contact with spout	0.2	0.2	0.5	-0.6	0.6	-0.7	-0.7	-0.3	-0.3	0.3	-0.4	0.5	-0.3	-0.3	0.2
Lifetime Intake	2.3	2.7	3.2	-1.8	1.8	-1.8	-1.7	-1.5	-1.7	1.7	-1.6	1.7	-1.5	-1.5	-1.0
Liver weight, left	3.7	6.0	8.2	-2.0	2.4	-2.0	-2.1	-2.1	-2.8	2.9	-2.3	2.7	-2.5	-2.5	-2.9
Liver weight, right	2.8	4.7	6.3	-2.2	2.2	-1.9	-2.0	-1.9	-2.3	2.3	-2.3	2.1	-2.5	-2.5	-1.4
Locomotor activity	1.3	2.1	3.8	-1.9	1.6	-1.3	-1.0	-1.4	-1.7	1.6	-1.5	1.0	-1.6	-1.6	-0.3
Locomotor testing distance	0.7	1.1	1.9	-1.4	1.1	-1.0	-0.6	-1.1	-1.2	1.2	-1.1	0.7	-1.2	-1.2	0.0
Locomotor testing rearing	0.9	1.3	2.3	-1.5	1.2	-1.0	-0.8	-0.9	-1.4	1.4	-1.3	0.7	-1.4	-1.4	-0.2
Locomotion in novel chamber	0.9	1.1	8.9	-1.1	0.3	-0.7	-0.4	-0.9	0.3	-0.4	-0.4	-0.7	-0.3	-0.3	3.0
Locomotion in novel chamber post-restriction	0.1	0.1	0.3	-0.3	0.2	-0.2	0.1	-0.5	-0.4	0.4	0.2	0.2	0.3	0.3	-0.5
Fecal boli incidents, locomotor time 1	4.3	4.7	7.8	-2.6	2.5	-2.4	-2.1	-2.8	-2.4	2.4	-1.9	2.2	-1.5	-1.5	-0.9
Change in fecal boli incidents, locomotor task	5.4	5.1	7.3	2.7	-2.6	2.1	2.1	2.5	2.7	-2.7	2.0	-2.3	1.7	1.7	1.8
Time >=10cm from walls, locomotor time 1	1.8	1.9	3.3	-1.7	1.6	-1.8	-1.3	-1.6	-1.3	1.2	-1.3	1.5	-1.0	-1.0	-0.2
Bouts of movement, locomotor time 1	0.4	0.5	3.1	0.2	-0.5	0.1	-0.0	0.2	0.8	-0.9	-0.1	-0.6	-0.3	-0.3	1.8
Total resting periods, locomotor time 1	0.3	0.4	2.7	0.1	-0.3	-0.1	-0.2	-0.0	0.7	-0.8	-0.3	-0.5	-0.3	-0.3	1.6
Rest time, locomotor task time 1	0.5	0.6	2.0	-0.3	0.4	-0.8	-0.9	-1.4	0.1	-0.1	-1.0	0.7	-0.9	-0.9	0.7
Distance moved, locomotor task time 1	0.4	0.5	1.4	0.4	-0.6	0.7	0.9	1.2	0.4	-0.4	0.8	-0.9	0.6	0.6	0.2
Vertical activity count, locomotor time 1	1.0	1.0	2.4	0.5	-0.8	1.2	1.3	1.6	0.4	-0.4	1.2	-1.2	1.1	1.1	-0.1
Time >=10cm from walls, locomotor time 2	1.1	1.2	2.6	-1.4	1.3	-1.6	-1.5	-1.2	-0.8	0.7	-1.0	1.0	-0.6	-0.6	0.3
Bouts of movement, locomotor time 2	0.3	0.3	1.1	0.5	-0.5	-0.1	0.0	0.2	0.9	-1.0	0.3	-0.4	0.4	0.4	1.1
Total resting periods, locomotor time 2	0.5	0.5	1.5	0.7	-0.7	0.1	0.2	0.2	1.1	-1.2	0.3	-0.5	0.4	0.4	1.2
Rest time, locomotor task time 2	0.6	0.7	2.0	-0.4	0.5	-0.9	-0.7	-1.4	-0.0	-0.0	-1.1	0.8	-1.0	-1.0	0.7
Distance moved, locomotor task time 2	0.1	0.1	0.7	-0.2	0.1	0.0	0.2	0.3	-0.4	0.4	0.3	-0.0	0.3	0.3	-0.8
Vertical activity count, locomotor time 2	0.5	0.5	1.2	0.1	-0.2	0.7	0.5	1.1	-0.2	0.3	0.9	-0.4	0.9	0.9	-0.9
Light reinforcement 1	0.3	0.6	1.2	-1.1	0.9	-0.7	-0.8	-0.3	-0.8	0.7	-1.0	0.5	-1.0	-1.0	0.2
Light reinforcement 2	0.1	0.2	1.2	-0.2	-0.1	0.2	0.1	0.3	0.3	-0.4	-0.2	-0.5	-0.3	-0.3	1.1
Bone: marrow area	0.7	1.4	5.6	-0.9	1.1	-0.7	-0.7	-0.8	-1.7	1.8	-0.3	1.3	-0.2	-0.2	-2.4
Bone: maximum diameter	0.6	1.1	2.9	-1.2	1.2	-0.5	-0.7	-0.7	-1.6	1.7	-0.4	1.0	-0.2	-0.2	-1.7
Bone: maximum force	1.0	1.7	3.6	-1.6	1.5	-1.0	-1.2	-0.8	-1.9	1.9	-0.8	1.2	-0.6	-0.6	-1.5
Bone: maximum moment	0.7	1.3	3.1	-1.4	1.3	-0.7	-0.8	-0.6	-1.7	1.8	-0.6	1.0	-0.5	-0.5	-1.5
Mean time between licks in bursts	0.5	0.7	1.3	0.8	-0.9	0.9	0.9	1.1	0.7	-0.7	0.9	-0.9	0.8	0.8	0.5
Mean num. licks in bursts	0.3	0.3	0.6	-0.6	0.6	-0.5	-0.6	-0.7	-0.6	0.6	-0.4	0.5	-0.4	-0.4	-0.4
Cd content in liver	0.4	0.5	1.4	-1.2	0.8	-0.8	-0.8	-0.7	-0.5	0.5	-0.6	0.2	-0.3	-0.3	0.8
Co content in liver	0.1	0.1	0.2	0.1	-0.1	0.5	0.5	0.0	-0.2	0.3	0.1	-0.2	-0.1	-0.1	-0.5
Cu content in liver	0.1	0.1	0.3	0.0	-0.0	-0.2	-0.2	-0.1	0.3	-0.3	-0.5	0.1	-0.5	-0.5	0.4
Fe content in liver	0.4	0.5	1.1	0.6	-0.7	0.9	0.9	1.0	0.6	-0.5	0.6	-0.8	0.6	0.6	0.2
K content in liver	0.1	0.1	0.3	0.5	-0.4	0.3	0.3	0.5	0.5	-0.5	-0.0	-0.3	-0.3	-0.3	0.0
Mg content in liver	0.2	0.2	0.6	-0.3	0.2	-0.4	-0.4	-0.2	0.1	-0.1	-0.6	0.1	-0.8	-0.8	0.4
Mn content in liver	0.1	0.2	0.5	-0.3	0.3	-0.2	-0.2	0.2	-0.5	0.5	-0.3	0.4	-0.4	-0.4	-0.7
Na content in liver	0.1	0.1	0.7	-0.2	0.2	0.2	0.2	0.3	-0.5	0.6	0.1	0.1	0.0	0.0	-0.9
Rb content in liver	1.5	1.9	2.4	-1.3	1.4	-1.5	-1.5	-1.6	-1.1	1.1	-1.6	1.4	-1.5	-1.5	-0.3
Se content in liver	0.3	0.4	1.3	0.9	-0.8	0.4	0.4	0.1	1.1	-1.1	0.3	-0.5	0.3	0.3	0.5
Sr content in liver	1.3	1.2	2.4	0.9	-1.1	1.6	1.6	1.1	0.5	-0.4	1.3	-1.2	1.1	1.1	-0.1
Zn content in liver	2.7	3.0	4.5	-1.9	1.7	-1.8	-1.8	-1.7	-1.5	1.4	-2.1	1.4	-2.1	-2.1	-0.2
Bone: minimum diameter	1.6	3.0	9.6	-1.3	1.6	-1.0	-1.2	-1.6	-2.2	2.3	-1.0	1.9	-1.0	-1.0	-3.1
Time in familiar zone, hab. session 1	1.4	1.3	2.0	-1.3	1.1	-1.3	-1.4	-1.2	-0.7	0.6	-1.4	0.8	-1.3	-1.3	0.8
Time in novel zone, hab. session 1	0.1	0.1	0.1	0.3	-0.3	0.3	0.3	0.1	0.3	-0.3	0.2	-0.2	0.2	0.2	0.1
Total zone transitions, hab. session 1	0.1	0.1	0.2	0.0	-0.2	0.4	0.5	0.4	-0.1	0.1	0.1	-0.4	-0.2	-0.2	-0.0
Total locomotion distance, hab. session 1	0.1	0.1	0.5	0.2	-0.2	0.7	0.7	0.3	-0.3	0.3	0.2	-0.3	-0.1	-0.1	-0.6
Locomotion velocity, hab. session 1	0.3	0.4	1.1	0.6	-0.5	1.0	1.1	0.8	-0.1	0.2	0.5	-0.5	0.1	0.1	-0.8
Time in familiar zone, hab. session 2	0.2	0.2	0.4	-0.5	0.6	-0.5	-0.6	-0.3	-0.6	0.6	-0.3	0.6	-0.2	-0.2	-0.6
Time in novel zone, hab. session 2	0.7	0.7	1.4	0.8	-0.9	0.7	0.8	0.6	1.1	-1.1	0.5	-0.9	0.3	0.3	1.2
Total zone transitions, hab. session 2	1.1	1.5	2.4	0.7	-1.0	1.5	1.4	1.4	0.6	-0.6	1.5	-1.4	1.5	1.5	0.3
Total locomotion distance, hab. session 2	1.2	1.6	3.0	1.1	-1.3	1.7	1.7	1.7	0.8	-0.7	1.4	-1.5	1.2	1.2	0.3
Locomotion velocity, hab. session 2	0.9	1.2	2.4	0.8	-1.0	1.5	1.5	1.5	0.5	-0.4	1.2	-1.3	1.0	1.0	0.1
Novel to familiar place preference ratio	0.8	0.8	1.3	-0.7	0.8	-1.1	-1.2	-1.1	-0.5	0.4	-1.0	1.0	-1.0	-1.0	0.2
Novelty place preference	1.2	1.3	1.9	-0.9	1.1	-1.3	-1.4	-1.3	-0.8	0.8	-1.3	1.3	-1.3	-1.3	-0.1
Time in novel zone, NPP test	1.4	1.4	2.3	-1.0	1.1	-1.5	-1.5	-1.4	-0.8	0.7	-1.4	1.3	-1.3	-1.3	0.1
Total zone transitions, NPP test	0.9	1.3	2.2	1.0	-1.2	1.5	1.5	1.5	0.8	-0.8	1.1	-1.4	0.9	0.9	0.5
Total locomotion distance, NPP test	0.7	0.9	2.0	1.0	-1.0	1.4	1.4	1.3	0.5	-0.4	1.0	-1.0	0.7	0.7	-0.4
Locomotion velocity, NPP test	1.0	1.5	3.0	1.2	-1.2	1.7	1.7	1.6	0.6	-0.5	1.3	-1.2	1.0	1.0	-0.5
Intraocular pressure	0.1	0.2	0.6	-0.8	0.4	-0.3	-0.2	0.0	-0.5	0.5	-0.4	0.0	-0.5	-0.5	0.6
Delta distance traveled before/after self-admin	0.2	0.3	0.7	0.4	-0.3	0.5	0.7	0.1	0.1	-0.1	0.7	-0.3	0.7	0.7	-0.8
Delta ambulatory time before/after self-admin	0.4	0.4	0.7	0.7	-0.6	0.8	0.9	0.3	0.4	-0.3	0.9	-0.5	0.9	0.9	-0.5
Parametrial fat weight	0.1	0.1	0.5	0.7	-0.5	0.3	0.3	0.3	0.5	-0.5	0.2	-0.2	0.2	0.2	0.1
Pavlov. Cond. lever latency	1.1	1.4	2.3	-1.0	0.9	-1.3	-1.5	-1.4	-0.4	0.3	-1.5	0.8	-1.5	-1.5	1.0
Pavlov. Cond. magazine entry latency	0.0	0.1	0.2	-0.2	0.2	0.0	0.1	-0.4	-0.3	0.3	0.2	0.0	0.3	0.3	-0.3
Pavlov. Cond. change in total contacts	1.2	1.3	2.1	1.1	-1.1	1.4	1.5	1.2	0.6	-0.6	1.4	-1.0	1.4	1.4	-0.5
Pavlov. Cond. index score	0.3	0.4	1.0	0.3	-0.3	0.6	0.7	0.4	-0.1	0.2	0.9	-0.3	0.9	0.9	-1.0
Pavlov. Cond. latency score	0.4	0.6	1.1	0.5	-0.5	0.8	0.9	0.6	0.0	0.0	1.0	-0.5	1.1	1.1	-0.9
Pavlov. Cond. lever contacts	2.3	2.6	4.3	1.6	-1.4	1.9	2.0	1.8	0.7	-0.6	2.1	-1.2	2.1	2.1	-1.2
Pavlov. Cond. magazine entry number	0.6	0.7	1.5	1.0	-0.9	0.6	0.5	0.9	1.2	-1.2	0.4	-0.7	0.3	0.3	1.1
Pavlov. Cond. intertrial magazine entries	2.6	3.2	5.7	2.4	-2.1	1.7	1.8	1.7	2.1	-2.1	1.7	-1.5	1.6	1.6	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.4	0.6	-0.6	0.8	0.9	0.6	0.2	-0.2	1.1	-0.5	1.2	1.2	-0.8
Pavlov. Cond. response bias	0.3	0.4	1.2	0.2	-0.2	0.6	0.7	0.4	-0.2	0.3	0.8	-0.3	0.9	0.9	-1.1
Pavlov. Cond. lever latency	0.1	0.1	0.5	0.1	0.0	-0.4	-0.5	-0.5	0.4	-0.4	-0.1	0.3	-0.1	-0.1	0.7
Pavlov. Cond. magazine entry latency	1.3	1.5	2.6	1.5	-1.4	1.6	1.6	1.3	1.0	-0.9	1.2	-1.1	1.0	1.0	-0.6
Pavlov. Cond. change in total contacts	0.2	0.3	2.2	0.0	-0.1	0.6	0.6	0.7	-0.5	0.5	0.1	-0.1	-0.1	-0.1	-1.5
Pavlov. Cond. index score	0.6	0.8	1.6	0.8	-0.9	1.2	1.3	1.1	0.4	-0.4	0.9	-1.0	0.7	0.7	-0.6
Pavlov. Cond. latency score	0.7	0.9	1.9	0.9	-1.0	1.3	1.4	1.2	0.6	-0.6	0.9	-1.1	0.7	0.7	-0.4
Pavlov. Cond. lever contacts	0.1	0.2	0.9	-0.4	0.3	0.1	0.2	0.1	-0.7	0.7	-0.2	0.0	-0.2	-0.2	-1.0
Pavlov. Cond. magazine entry number	0.1	0.2	0.3	-0.3	0.4	-0.6	-0.6	-0.3	-0.2	0.2	-0.4	0.5	-0.4	-0.4	0.3
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.5	0.2	0.2	-0.4	-0.3	-0.3	-0.1	0.1	-0.5	0.7	-0.5	-0.5	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	1.8	0.9	-0.9	1.4	1.4	1.1	0.5	-0.4	1.0	-1.0	0.8	0.8	-0.7
Pavlov. Cond. response bias	0.2	0.2	0.7	0.2	-0.3	0.7	0.7	0.6	-0.2	0.2	0.3	-0.4	0.2	0.2	-0.8
Time in closed arm before self-admin	4.8	5.4	7.3	-2.7	2.6	-2.7	-2.6	-2.3	-2.3	2.2	-2.5	2.2	-2.3	-2.3	-0.8
Time in closed arm after self-admin	1.8	1.8	3.8	-1.0	1.2	-1.1	-1.2	-1.1	-1.4	1.4	-1.3	1.5	-1.3	-1.3	-1.9
Time in open arm before self-admin	1.2	1.3	1.6	1.1	-1.2	1.2	1.2	1.3	1.0	-1.0	1.3	-1.1	1.2	1.2	0.7
Time in open arm after self-admin	0.7	0.7	1.2	1.1	-1.0	0.8	0.9	0.6	1.0	-1.0	0.8	-0.7	0.8	0.8	0.6
Bone: periosteal estimation	1.1	2.2	6.2	-1.4	1.6	-0.9	-1.0	-1.1	-2.2	2.2	-0.6	1.5	-0.4	-0.4	-2.5
Bone: periosteal perimeter	0.7	1.1	3.5	-1.1	1.1	-0.3	-0.5	-0.8	-1.7	1.7	-0.2	0.9	-0.1	-0.1	-1.9
Bone: post-yield work	0.1	0.2	1.5	0.1	0.1	0.1	0.0	0.1	-0.5	0.5	0.0	0.5	0.0	0.0	-1.2
Progressive ratio test 1 active lever presses	1.3	1.3	2.1	-1.2	1.1	-1.2	-1.2	-1.1	-1.0	1.0	-1.4	1.0	-1.4	-1.4	-0.3
Progressive ratio test 1 breakpoint	1.1	1.1	1.9	-1.2	1.0	-1.1	-1.1	-1.1	-0.8	0.8	-1.3	0.8	-1.4	-1.4	0.1
Progressive ratio test 1 inactive lever presses	1.4	1.6	2.9	-1.2	1.1	-1.0	-1.2	-1.2	-1.1	1.1	-1.5	1.0	-1.7	-1.7	-0.7
Progressive ratio test 2 active lever presses	3.1	3.4	3.9	-2.0	2.0	-1.9	-1.9	-1.8	-1.9	1.9	-1.9	1.8	-1.8	-1.8	-1.2
Progressive ratio test 2 breakpoint	3.5	3.9	4.4	-2.1	2.1	-2.0	-2.0	-1.9	-2.1	2.1	-2.0	2.0	-2.0	-2.0	-1.3
Progressive ratio test 2 inactive lever presses	4.4	5.0	6.1	-2.3	2.4	-2.2	-2.2	-2.5	-2.4	2.4	-2.3	2.3	-2.2	-2.2	-1.5
Incentive Sensitization - Responses	4.3	4.4	5.8	-2.2	2.3	-2.0	-2.0	-1.9	-2.4	2.4	-2.0	2.2	-1.8	-1.8	-1.8
Incentive Sensitization - Breakpoint	4.1	4.2	5.6	-2.2	2.2	-2.0	-2.0	-1.9	-2.4	2.4	-1.9	2.1	-1.8	-1.8	-1.8
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	-0.6	0.5	-0.6	-0.6	-0.5	-0.4	0.4	-0.4	0.4	-0.2	-0.2	0.2
Progressive ratio	0.3	0.3	0.6	-0.4	0.5	-0.5	-0.7	-0.5	-0.6	0.6	-0.5	0.7	-0.5	-0.5	-0.7
Food seeking constrained by brief footshock	2.0	2.5	3.3	-1.2	1.5	-1.6	-1.6	-1.7	-1.4	1.4	-1.7	1.8	-1.8	-1.8	-1.4
Seeking ratio, punishment vs. effort	0.0	0.1	0.1	-0.1	0.2	-0.2	0.0	-0.3	-0.2	0.2	-0.3	0.2	-0.3	-0.3	-0.3
Retroperitoneal fat weight	0.5	1.5	2.4	1.2	-1.3	1.0	1.0	1.0	1.5	-1.5	1.2	-1.3	1.3	1.3	1.0
Reaction time number correct	0.8	1.2	1.7	1.3	-1.2	1.1	1.1	1.0	1.2	-1.2	1.0	-1.0	0.9	0.9	0.6
Reaction time mean minus median	1.0	1.3	2.2	-1.3	1.0	-1.3	-1.2	-1.5	-0.4	0.3	-1.3	0.6	-1.4	-1.4	1.3
Reaction time mean minus median AUC	2.1	2.7	3.9	-1.9	1.6	-1.9	-1.9	-2.0	-0.9	0.8	-1.9	1.2	-1.9	-1.9	1.1
Reaction time num false alarms	0.0	0.1	0.2	-0.4	0.2	-0.2	-0.0	-0.2	-0.2	0.2	-0.3	0.0	-0.3	-0.3	0.3
Reaction time num false alarms AUC	0.0	0.1	0.2	0.0	-0.2	0.3	0.4	0.1	0.2	-0.2	0.1	-0.3	0.2	0.2	0.5
Reaction time trials correct on left	0.8	1.2	1.7	1.3	-1.2	1.1	1.1	1.0	1.2	-1.2	1.0	-1.0	0.9	0.9	0.6
Reaction time trials on left	0.8	1.2	1.8	1.3	-1.2	1.1	1.1	1.0	1.2	-1.2	1.0	-1.0	0.9	0.9	0.6
Reaction time mean	0.2	0.3	0.7	-0.6	0.6	-0.5	-0.5	-0.9	-0.5	0.5	-0.5	0.5	-0.5	-0.5	-0.3
Reaction time mean AUC	0.0	0.0	0.2	-0.1	0.1	-0.1	-0.1	-0.4	0.0	-0.0	-0.1	0.0	-0.2	-0.2	0.0
Median of all reaction times	0.0	0.1	0.4	0.0	0.0	0.1	0.1	-0.3	-0.2	0.2	0.2	0.1	0.2	0.2	-0.6
Reaction time omissions	0.0	0.1	0.2	0.0	-0.1	0.1	0.1	-0.4	0.1	-0.1	-0.2	-0.1	-0.4	-0.4	0.2
Reaction time false alarm rate	0.1	0.1	0.3	-0.6	0.4	-0.2	-0.1	-0.3	-0.4	0.4	-0.3	0.2	-0.2	-0.2	0.1
Reaction time premature initiation rate	1.0	1.3	1.9	1.0	-1.1	1.3	1.1	1.0	1.1	-1.1	1.4	-1.2	1.4	1.4	0.5
Reaction time premature initiations	1.8	2.5	3.1	1.6	-1.6	1.7	1.6	1.5	1.5	-1.5	1.8	-1.6	1.7	1.7	0.8
Std. dev. reaction times	0.3	0.5	1.3	-0.9	0.6	-0.7	-0.7	-1.1	-0.2	0.2	-0.7	0.2	-0.8	-0.8	0.7
Reaction time trials completed	0.8	1.2	1.8	1.3	-1.2	1.1	1.1	1.0	1.2	-1.2	1.0	-1.0	0.9	0.9	0.6
Reaction time trials AUC	0.5	0.8	1.3	1.2	-1.0	0.9	0.9	0.8	1.0	-1.0	0.8	-0.8	0.7	0.7	0.4
Run reversals in cocaine runway, females	0.7	0.6	1.0	-1.0	0.7	-0.8	-0.9	-0.8	-0.5	0.4	-1.0	0.4	-1.0	-1.0	0.8
Run reversals in cocaine runway, males	2.1	2.0	3.3	-1.7	1.5	-1.8	-1.8	-1.8	-0.9	0.8	-1.6	1.1	-1.4	-1.4	0.7
Latency to leave start box in cocaine runway	0.6	0.7	1.5	0.9	-0.7	0.6	0.7	0.9	0.7	-0.7	1.1	-0.6	1.2	1.2	0.1
Latency to leave start box in cocaine runway, F	0.2	0.2	0.4	0.2	-0.3	0.2	0.2	0.4	0.5	-0.5	0.4	-0.5	0.4	0.4	0.7
Latency to leave start box in cocaine runway, M	2.0	1.9	3.3	1.8	-1.4	1.2	1.4	1.3	1.1	-1.0	1.7	-0.8	1.8	1.8	-0.5
Std. dev. time between licks in bursts	0.1	0.1	0.3	-0.2	-0.0	0.3	0.3	0.6	-0.2	0.2	0.5	-0.3	0.6	0.6	0.0
Total sessions with >9 infusions	1.2	1.3	3.2	-1.1	1.2	-0.9	-0.9	-0.9	-1.5	1.5	-0.8	1.2	-0.8	-0.8	-1.8
Short access day 1 total inactive lever presses	0.1	0.1	0.7	0.0	-0.1	0.4	0.1	-0.3	-0.1	0.1	0.4	-0.3	0.3	0.3	-0.8
Short access day 10 total inactive lever presses	1.4	1.6	3.0	-1.7	1.5	-1.3	-1.3	-1.5	-1.5	1.4	-1.1	1.1	-0.9	-0.9	-0.3
Short access day 1 total infusions	2.1	2.2	2.8	-1.7	1.6	-1.5	-1.6	-1.6	-1.5	1.5	-1.6	1.3	-1.6	-1.6	-0.8
Short access day 10 total infusions	2.2	2.4	3.2	-1.7	1.6	-1.7	-1.8	-1.7	-1.4	1.3	-1.8	1.4	-1.7	-1.7	-0.4
Short access total infusions	1.4	1.6	2.0	-1.3	1.3	-1.4	-1.4	-1.3	-1.2	1.2	-1.4	1.2	-1.4	-1.4	-0.7
Short access day 1 locomotion	0.1	0.1	0.2	0.0	-0.2	0.2	0.2	0.4	0.3	-0.3	0.1	-0.4	0.0	0.0	0.3
Short access day 10 total locomotion	0.7	0.8	1.4	-1.2	0.8	-0.8	-0.9	-1.2	-0.6	0.6	-1.0	0.4	-1.1	-1.1	0.2
Short access total locomotion	0.2	0.3	0.6	-0.6	0.4	-0.4	-0.6	-0.4	-0.1	0.1	-0.7	0.0	-0.8	-0.8	0.4
One hour access (0.3 mA shock)	1.9	2.2	4.0	-1.8	1.8	-1.4	-1.3	-1.1	-2.0	2.0	-1.2	1.5	-1.1	-1.1	-1.3
Compulsive drug intake	1.5	1.5	2.9	-1.2	1.3	-1.0	-0.9	-0.7	-1.6	1.6	-0.9	1.4	-0.8	-0.8	-1.7
One hour access (shock baseline)	0.5	0.5	1.4	-1.2	0.9	-0.8	-0.8	-0.6	-0.8	0.8	-0.7	0.5	-0.6	-0.6	0.3
Social response proportion	0.0	0.0	0.1	0.2	-0.1	-0.0	-0.2	-0.1	0.3	-0.3	-0.2	-0.1	-0.3	-0.3	0.2
Social responses	0.1	0.2	0.6	-0.8	0.5	-0.4	-0.4	-0.5	-0.5	0.4	-0.4	0.0	-0.4	-0.4	0.2
Social time	0.3	0.4	1.0	0.5	-0.5	0.5	0.6	0.6	0.3	-0.2	0.9	-0.4	1.0	1.0	-0.4
Soleus weight	0.3	0.7	2.0	-0.2	-0.3	0.8	0.8	0.9	-0.1	0.2	1.2	-1.0	1.4	1.4	0.2
Bone: stiffness	1.2	1.9	3.7	-1.5	1.5	-0.9	-1.1	-0.9	-1.9	1.9	-1.0	1.4	-0.9	-0.9	-1.9
Tibialis anterior weight	0.1	0.3	2.1	-0.6	0.0	0.3	0.4	0.5	-0.0	0.0	0.3	-0.9	0.2	0.2	1.4
Time to tail flick, vehicle, before self-admin	2.1	2.1	3.1	1.4	-1.5	1.2	1.6	1.6	1.7	-1.8	1.3	-1.5	1.3	1.3	1.4
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.9	0.3	0.0	-0.1	-0.1	0.2	-0.1	0.2	-0.5	0.5	-0.7	-0.7	-0.9
Time to tail flick, test, before self-admin	0.1	0.1	0.5	-0.1	-0.1	0.1	0.1	-0.0	0.1	-0.1	-0.1	-0.3	-0.2	-0.2	0.7
Time to tail flick, test, after self-admin	0.4	0.4	1.1	-0.4	0.6	-0.5	-0.7	-0.7	-0.8	0.8	-0.3	0.9	-0.2	-0.2	-1.0
Delta time to tail flick, vehicle, before/after SA	1.6	1.6	2.4	-0.9	1.1	-1.0	-1.3	-1.1	-1.3	1.3	-1.4	1.3	-1.5	-1.5	-1.3
Delta time to tail flick, test, before/after SA	0.3	0.3	1.8	0.4	-0.1	0.2	0.1	0.4	-0.2	0.3	0.5	0.4	0.6	0.6	-1.3
Tibia length	0.5	1.4	2.9	-1.2	1.3	-0.9	-1.0	-1.0	-1.7	1.7	-0.7	1.3	-0.5	-0.5	-1.4
Ambulatory time before self-admin	4.5	4.7	6.5	-2.5	2.5	-2.4	-2.0	-1.9	-2.5	2.5	-2.1	2.3	-1.9	-1.9	-1.1
Ambulatory time after self-admin	2.3	2.5	4.3	-2.0	1.9	-1.6	-1.3	-1.6	-2.1	2.1	-1.2	1.6	-1.0	-1.0	-1.2
Bone: tissue strength	0.1	0.1	0.5	-0.0	0.0	0.2	0.3	0.2	-0.2	0.2	-0.4	-0.0	-0.7	-0.7	-0.4
Total heroin consumption	1.2	1.4	2.3	-1.5	1.3	-1.4	-1.5	-1.3	-0.9	0.8	-1.3	0.9	-1.1	-1.1	0.6
Bone: trabecular number	0.3	0.4	0.9	0.3	-0.5	0.8	0.7	0.7	0.3	-0.3	0.9	-0.8	0.9	0.9	0.2
Bone: trabecular spacing	0.1	0.1	0.2	0.5	-0.3	0.0	0.1	0.1	0.5	-0.5	0.2	-0.0	0.3	0.3	0.1
Bone: trabecular thickness	1.0	1.2	1.9	-1.2	1.2	-1.0	-1.1	-1.2	-1.4	1.4	-0.7	1.2	-0.6	-0.6	-1.2
Bone: trabecular tissue density	0.5	0.7	1.1	-0.7	0.9	-0.8	-1.0	-0.7	-0.9	0.9	-0.8	1.0	-0.7	-0.7	-0.8
Water consumed over 24 hours	0.1	0.1	0.2	0.3	-0.2	0.2	0.1	0.1	0.1	-0.1	0.4	-0.0	0.5	0.5	-0.2
Number of responses in last shaping day	0.2	0.2	0.4	-0.5	0.4	-0.4	-0.4	-0.3	-0.2	0.2	-0.6	0.2	-0.7	-0.7	0.2