Hub : Genes

Usp48

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye mRNA stability Usp48 0.52 0.16 9.2e-06 0.02 0.21 0.14 0.19 1.5e-01 4.3e-04 3.8e-03 6.6e-04
2 Eye gene expression Usp48 0.67 0.15 6.4e-07 0.08 0.15 0.09 0.11 2.4e-02 2.6e-03 1.7e-02 1.0e-02
3 IL gene expression Usp48 0.17 0.11 6.3e-04 0.16 0.14 0.14 0.14 1.5e-04 2.5e-04 3.6e-04 3.5e-04
4 Adipose intron excision ratio chr5_155084347_155093685 0.04 0.03 2.5e-04 0 0.02 0.01 0.01 1.9e-01 2.8e-03 4.4e-02 3.9e-02
5 Adipose intron excision ratio chr5_155093805_155095066 0.05 0.04 1.9e-04 0.01 0.02 0.02 0.01 8.6e-03 1.6e-03 5.8e-03 2.1e-02
6 PL gene expression Usp48 0.09 0.06 5.1e-13 0.13 0.12 0.12 0.12 7.1e-14 1.1e-12 4.8e-13 1.4e-13
7 IC gene expression Usp48 0.07 0.05 7.9e-04 0.04 0.07 0.04 0.06 8.1e-03 5.3e-04 1.2e-02 1.5e-03
8 BLA gene expression Usp48 0.11 0.08 1.1e-03 0.03 0.03 0.02 0.02 7.8e-03 1.5e-02 3.2e-02 4.8e-02
9 Brain gene expression Usp48 0.06 0.04 2.8e-08 0.09 0.09 0.09 0.08 1.5e-08 8.0e-09 1.7e-08 3.6e-08
10 Adipose gene expression Usp48 0.05 0.04 4.2e-04 0.04 0.03 0.03 0.04 2.3e-05 4.0e-04 6.3e-04 5.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.10.2-0.30.20.0-0.40.5-0.2-0.2-0.2-0.10.4
Area under the delay curve0.40.50.70.6-0.7-0.60.8-0.8-0.7-0.7-0.6-0.8-0.7
BMI with tail0.20.73.3-1.10.70.8-0.10.00.70.50.6-0.0-1.8
BMI without tail1.34.05.8-2.42.22.3-1.81.72.22.12.21.8-0.1
Body weight1.87.711.4-3.03.03.4-3.03.02.72.62.62.61.6
Weight adjusted by age1.01.52.9-1.01.21.4-0.90.81.51.61.71.40.3
Bone surface0.10.10.4-0.20.20.3-0.50.5-0.2-0.2-0.30.00.6
Bone volume0.10.20.7-0.20.10.0-0.50.6-0.3-0.3-0.40.00.8
Breakpoint value in progressive ratio session1.21.52.2-1.41.41.2-1.11.01.51.41.41.2-0.0
Number of licking bursts0.00.00.10.1-0.0-0.30.2-0.20.10.20.00.0-0.4
Context. condit. distance diff. score0.70.81.8-1.31.10.8-0.90.91.00.80.90.7-0.0
Locomotion velocity, session 11.11.22.30.8-1.0-0.80.8-0.7-1.5-1.5-1.4-1.3-0.3
Locomotion distance, session 11.72.23.71.2-1.4-1.41.2-1.2-1.9-1.9-1.7-1.8-0.4
Locomotion velocity, session 23.54.05.92.4-2.3-2.01.8-1.8-2.3-2.2-2.1-1.90.4
Locomotion distance, session 20.70.92.00.7-0.8-0.80.3-0.3-1.4-1.4-1.2-1.01.0
Locomotion velocity, session 31.51.82.51.0-1.2-1.51.5-1.5-1.1-1.2-1.0-1.5-1.6
Locomotion distance, session 30.80.82.2-1.51.20.5-0.90.90.90.71.00.6-0.4
Stereotopy head waving bouts, day 31.21.42.61.6-1.4-1.01.1-1.0-1.4-1.3-1.3-1.0-0.2
Stereotopy head waving duration, day 30.70.82.11.5-1.2-0.60.9-0.8-1.0-0.8-0.9-0.60.1
Locomotion velocity, session 72.22.43.7-1.91.81.4-1.61.51.61.61.71.40.1
Locomotion distance, session 70.40.50.8-0.90.80.7-0.70.70.70.70.80.60.1
Stereotopy head waving bouts, day 70.10.10.5-0.20.20.7-0.20.20.30.40.20.30.0
Stereotopy head waving duration, day 70.10.20.5-0.10.20.6-0.30.40.20.30.20.40.7
Locomotion velocity, session 80.70.91.40.7-0.9-0.30.9-0.8-1.2-1.1-1.2-1.2-0.8
Locomotion distance, session 80.10.10.6-0.80.40.1-0.40.3-0.0-0.20.0-0.2-0.2
Degree of sensitization distance0.50.51.51.2-0.9-0.30.8-0.7-0.6-0.4-0.7-0.30.4
Degree of sensitization stereotypy1.11.21.9-1.11.11.4-1.01.01.21.21.11.10.8
Conditioned locomotion1.51.72.31.5-1.4-0.81.5-1.5-1.2-1.1-1.2-1.3-1.3
Cocaine response after cond. corrected0.40.41.00.9-0.7-0.61.0-1.0-0.2-0.1-0.1-0.3-0.8
Cocaine response after cond. not corrected0.10.10.30.5-0.3-0.30.5-0.50.20.30.20.1-0.5
Cocaine response before conditioning1.51.82.7-1.41.41.2-1.61.61.31.21.01.41.3
Saline control response0.20.30.70.3-0.4-0.00.7-0.7-0.4-0.5-0.6-0.7-0.8
Bone: connectivity density0.30.40.7-0.70.70.6-0.80.80.40.40.50.50.7
Bone: cortical apparent density1.41.93.8-1.41.41.1-1.11.11.71.71.91.5-0.0
Bone: cortical area1.01.62.9-1.51.41.3-1.71.70.80.80.71.01.2
Bone: cortical porosity0.91.01.81.3-1.2-0.90.8-0.7-1.2-1.1-1.1-0.80.6
Bone: cortical porosity1.21.32.41.6-1.3-0.90.9-0.8-1.3-1.2-1.3-0.80.9
Bone: cortical thickness0.61.02.1-1.41.20.9-1.21.20.90.80.80.70.4
Bone: cortical thickness0.20.20.6-0.2-0.1-0.80.2-0.2-0.3-0.4-0.4-0.5-0.8
Bone: cortical tissue density1.21.63.4-1.21.30.9-0.90.91.61.61.81.3-0.2
Condit. Reinf. active minus inactive responses0.40.51.11.1-0.8-1.00.5-0.4-0.6-0.5-0.6-0.30.7
Condit. Reinf. active-inactive response ratio0.20.20.80.9-0.6-0.60.3-0.3-0.2-0.2-0.4-0.00.6
Condit. Reinf. active responses0.40.63.70.8-0.4-0.6-0.20.3-0.5-0.4-0.50.11.9
Condit. Reinf. inactive responses0.50.74.80.00.10.0-0.80.9-0.4-0.2-0.20.32.2
Incentive salience index mean0.40.52.30.8-0.5-1.2-0.10.1-0.5-0.5-0.50.11.5
Condit. Reinf. lever presses0.50.84.3-0.10.3-0.6-1.01.10.10.00.10.72.1
Condit. Reinf. active minus inactive responses0.10.10.3-0.0-0.2-0.40.3-0.3-0.3-0.4-0.2-0.5-0.6
Condit. Reinf. active-inactive response ratio0.91.11.71.1-1.1-0.91.3-1.3-1.0-0.9-0.7-1.1-1.0
Condit. Reinf. active responses0.20.31.0-1.00.70.2-0.80.80.20.00.20.20.4
Condit. Reinf. inactive responses2.22.85.5-2.01.81.2-2.32.41.10.90.91.42.0
Condit. Reinf. lever presses0.40.51.2-0.1-0.1-1.0-0.40.5-0.8-1.0-0.6-0.51.1
Condit. Reinf. lever reinforcers received0.30.40.9-1.00.70.2-0.91.00.20.00.20.20.6
Conditioned reinforcement - actives1.01.72.5-1.11.21.1-1.51.61.11.11.11.41.6
Conditioned reinforcement - inactives0.91.32.1-1.21.21.4-1.31.31.01.01.01.11.0
Conditioned locomotion2.33.03.5-1.91.81.8-1.71.71.81.81.91.70.8
Patch foraging indifference point 0 sec0.10.20.8-0.90.60.4-0.60.60.20.10.20.2-0.2
Patch foraging indifference point AUC1.21.72.9-1.71.51.0-1.41.41.31.21.31.20.5
Delay disc. indifference point, 0s delay1.01.11.70.7-1.0-0.91.0-1.0-1.0-1.3-1.1-1.3-1.1
Delay disc. indifference point, 16s delay0.00.00.10.1-0.1-0.20.1-0.0-0.2-0.1-0.1-0.00.1
Delay disc. indifference point, 2s delay0.30.30.60.5-0.5-0.40.6-0.7-0.4-0.5-0.6-0.6-0.8
Delay disc. indifference point, 24s delay0.10.20.60.5-0.4-0.60.1-0.1-0.4-0.2-0.3-0.00.8
Delay disc. indifference point, 4s delay0.40.40.50.7-0.7-0.20.7-0.7-0.7-0.6-0.7-0.7-0.4
Delay disc. indifference point, 8s delay0.50.50.70.6-0.7-0.70.8-0.8-0.7-0.8-0.6-0.9-0.8
Indifference point function ln k3.45.98.52.9-2.7-2.52.2-2.1-2.9-2.6-2.6-2.3-0.1
Indifference point function log k3.45.98.52.9-2.7-2.52.2-2.1-2.9-2.6-2.6-2.3-0.1
Patch foraging total patch changes 0 sec0.10.10.5-0.70.40.2-0.50.5-0.1-0.1-0.0-0.0-0.2
Patch foraging total patch changes 12 sec2.02.63.6-1.91.81.8-1.91.91.41.31.51.41.1
Patch foraging total patch changes 18 sec1.01.62.7-1.71.51.3-1.51.51.00.91.11.00.6
Patch foraging total patch changes 24 sec0.81.43.3-1.81.51.2-1.11.01.11.01.20.7-0.8
Patch foraging total patch changes 6 sec2.63.97.0-2.62.32.1-2.02.01.91.92.11.7-0.0
Patch foraging time to switch 0 sec0.81.72.3-1.11.21.5-1.21.11.41.51.51.50.7
Patch foraging water rate 0 sec1.53.13.91.6-1.7-1.51.8-1.8-1.9-1.8-1.9-2.0-1.6
Patch foraging water rate 12 sec1.53.14.21.3-1.6-1.81.7-1.7-1.9-1.9-1.9-2.0-1.8
Patch foraging water rate 18 sec0.81.22.51.0-1.0-1.00.3-0.2-1.5-1.4-1.6-0.91.2
Patch foraging water rate 24 sec2.13.05.02.1-2.0-1.01.6-1.5-2.0-1.9-2.2-1.7-0.0
Patch foraging water rate 6 sec3.14.45.22.1-2.2-1.92.2-2.1-2.3-2.2-2.2-2.3-1.5
Seeking ratio, delayed vs. immediate footshock0.30.31.4-0.1-0.2-0.20.5-0.5-0.4-0.6-0.4-0.8-1.2
Distance traveled before self-admin4.05.27.6-2.82.62.1-2.32.22.62.52.22.20.5
Distance traveled after self-admin4.35.27.5-2.72.62.6-2.32.32.52.32.12.20.6
Extensor digitorum longus weight0.10.50.90.1-0.4-0.40.4-0.4-0.9-1.0-0.7-1.0-0.8
Bone: elastic displacement0.00.00.1-0.10.10.4-0.20.2-0.1-0.2-0.1-0.10.3
Bone: elastic work0.00.10.2-0.40.30.3-0.30.30.1-0.00.2-0.0-0.1
Bone: endosteal estimation0.41.03.0-0.50.71.1-1.31.40.30.40.20.91.7
Bone: endosteal perimeter0.20.41.00.4-0.4-0.3-0.20.3-0.9-0.9-1.0-0.40.9
Epididymis fat weight0.00.10.20.4-0.30.30.3-0.3-0.2-0.1-0.3-0.10.2
Delta time in closed arm before/after self-admin0.50.42.40.7-0.5-0.5-0.10.2-0.7-0.5-0.4-0.01.5
Delta time in open arm before/after self-admin0.10.10.4-0.10.20.6-0.20.20.30.4-0.00.30.2
Diff in mean of infusions in LGA sessions0.10.20.9-0.10.20.3-0.50.50.20.20.10.40.9
Delay discount exponential model param0.30.40.5-0.60.60.4-0.70.70.60.60.50.70.6
Extinction: sum of active levers before priming0.20.20.5-0.30.40.7-0.50.50.30.30.10.40.5
Active lever presses in extinction session 60.10.10.2-0.10.20.5-0.10.10.30.30.20.2-0.0
Bone: final force1.22.03.3-1.81.61.2-1.61.61.31.21.31.30.7
Bone: final moment0.91.42.6-1.61.41.0-1.51.51.00.91.01.00.6
Food consumed during 24 hour testing period0.71.01.7-0.81.01.3-0.80.81.21.21.11.10.3
Glucose2.13.35.8-1.61.82.1-1.31.22.32.32.41.9-0.1
Heart weight0.61.01.9-1.11.11.0-0.70.61.41.31.11.0-0.5
Delay discount hyperbolic model param0.50.50.6-0.70.80.6-0.80.80.80.70.70.80.6
Intermittent access intake day 1-15 change0.10.21.3-0.10.1-0.3-0.50.6-0.3-0.2-0.40.11.2
Intermittent access intake escalation0.10.21.0-0.10.1-0.3-0.60.6-0.3-0.3-0.40.11.0
Intermittent access intake escalation 20.40.51.20.6-0.5-0.9-0.10.2-0.8-0.8-0.9-0.31.1
Intermitt. access day 1 inactive lever presses1.45.36.7-2.32.42.1-2.62.62.12.12.32.32.1
Intermitt. access day 15 inactive lever presses0.61.21.5-1.21.20.9-1.11.11.21.21.11.10.6
Intermitt. access escalation Index0.40.51.8-1.20.80.4-0.30.20.70.50.40.1-1.4
Intermittent access day 1 total infusions5.99.511.7-3.33.33.4-3.02.93.33.33.43.11.2
Intermittent access day 15 total infusions3.24.85.9-2.42.42.2-2.42.42.12.12.22.21.4
Intermittent access terminal intake (last 3 days)3.14.15.5-2.12.11.9-2.32.31.91.81.82.11.7
Intermittent access total infusions5.36.37.2-2.62.72.6-2.62.62.62.52.62.61.5
Intermittent access day 1 locomotion1.72.23.8-1.61.61.9-1.31.21.51.51.81.30.1
Intermittent access day 15 total locomotion0.81.41.9-1.01.11.4-1.41.41.01.01.01.21.4
Intermittent access total locomotion3.33.94.9-2.22.22.2-2.22.11.91.92.01.91.0
Intermittent access standard deviation1.12.43.7-1.61.61.3-1.91.91.31.31.31.61.5
Left kidney weight7.032.537.8-5.96.06.1-6.26.15.65.55.45.84.1
Right kidney weight3.616.220.4-3.74.04.0-4.54.53.73.83.64.34.1
Cocaine induced anxiety0.20.21.0-0.10.30.5-0.50.50.30.40.10.61.0
Post-drug Anxiety0.20.30.50.6-0.6-0.60.4-0.4-0.5-0.5-0.7-0.40.3
Baseline Anxiety1.01.21.80.9-1.0-1.31.2-1.2-1.0-1.1-1.0-1.2-1.0
Tail length3.413.216.0-3.03.53.7-4.04.03.33.53.44.03.9
Length with tail3.013.216.6-3.23.54.0-4.04.13.23.33.23.83.8
Length without tail0.72.23.1-1.41.51.8-1.61.61.41.41.31.51.4
Times rat made contact with spout0.20.30.6-0.50.50.3-0.30.30.80.70.70.5-0.1
Lifetime Intake4.55.56.2-2.42.52.4-2.52.52.42.42.42.41.5
Liver weight, left2.33.87.8-1.61.72.2-2.42.51.11.21.31.82.8
Liver weight, right2.44.25.7-1.72.02.0-2.42.41.71.91.72.32.3
Locomotor activity1.32.04.0-2.01.71.3-1.71.61.41.11.11.10.4
Locomotor testing distance0.51.01.9-1.41.21.3-1.21.20.90.70.60.70.3
Locomotor testing rearing0.71.52.6-1.61.41.6-1.41.41.00.80.80.90.5
Locomotion in novel chamber1.01.38.7-1.30.70.80.2-0.30.90.30.4-0.4-2.9
Locomotion in novel chamber post-restriction0.10.10.60.1-0.00.3-0.20.2-0.0-0.1-0.30.00.8
Fecal boli incidents, locomotor time 14.66.79.5-2.82.83.1-2.72.72.72.52.32.51.4
Change in fecal boli incidents, locomotor task5.05.07.12.7-2.5-2.52.5-2.5-2.0-2.1-2.0-2.1-1.0
Time >=10cm from walls, locomotor time 12.22.43.6-1.71.71.4-1.51.41.91.81.41.70.4
Bouts of movement, locomotor time 10.40.52.70.3-0.4-0.20.8-0.90.1-0.1-0.0-0.6-1.7
Total resting periods, locomotor time 10.30.42.20.2-0.3-0.10.7-0.80.2-0.00.1-0.4-1.5
Rest time, locomotor task time 10.20.30.90.3-0.11.00.4-0.50.50.60.40.3-0.7
Distance moved, locomotor task time 10.40.61.80.2-0.5-1.30.4-0.4-0.8-1.0-0.7-0.9-0.5
Vertical activity count, locomotor time 10.40.92.40.3-0.6-1.60.3-0.3-1.3-1.3-1.1-1.1-0.3
Time >=10cm from walls, locomotor time 20.91.32.5-1.31.21.1-0.70.61.61.41.51.0-0.6
Bouts of movement, locomotor time 20.20.41.20.5-0.5-0.50.9-0.90.0-0.0-0.1-0.4-1.1
Total resting periods, locomotor time 20.30.61.50.8-0.7-0.61.1-1.2-0.2-0.2-0.3-0.5-1.2
Rest time, locomotor task time 20.40.51.2-0.20.41.1-0.0-0.00.91.10.60.7-0.6
Distance moved, locomotor task time 20.10.10.2-0.30.20.1-0.40.40.0-0.10.10.00.3
Vertical activity count, locomotor time 20.20.30.7-0.1-0.1-0.8-0.20.2-0.7-0.8-0.4-0.50.5
Light reinforcement 10.20.61.2-1.11.00.5-0.80.70.70.80.70.7-0.1
Light reinforcement 20.10.21.3-0.2-0.0-0.40.3-0.4-0.1-0.10.0-0.3-1.2
Bone: marrow area0.40.92.9-0.50.71.0-1.31.40.20.40.10.91.7
Bone: maximum diameter0.61.12.2-1.01.01.1-1.41.50.50.50.30.81.4
Bone: maximum force0.81.42.5-1.51.40.9-1.61.60.90.80.81.00.9
Bone: maximum moment0.50.92.0-1.31.10.7-1.41.40.60.50.40.71.0
Mean time between licks in bursts0.20.50.80.6-0.7-0.80.6-0.6-0.8-0.9-0.9-0.8-0.2
Mean num. licks in bursts0.20.40.7-0.60.60.8-0.60.60.60.60.70.60.4
Cd content in liver5.46.010.1-3.22.92.0-2.52.42.82.42.72.20.1
Co content in liver0.70.82.3-0.70.70.8-1.21.30.30.20.40.71.5
Cu content in liver0.30.31.2-0.20.31.1-0.10.10.60.70.60.6-0.2
Fe content in liver0.00.00.20.1-0.1-0.40.1-0.1-0.1-0.1-0.1-0.00.1
K content in liver0.00.00.00.1-0.10.20.1-0.1-0.00.00.2-0.0-0.2
Mg content in liver0.30.30.7-0.40.50.9-0.30.30.70.70.80.6-0.3
Mn content in liver0.91.01.1-0.91.01.0-1.01.01.01.01.01.00.7
Na content in liver0.20.20.7-0.40.40.1-0.60.70.10.10.40.30.9
Rb content in liver2.83.25.1-1.51.72.3-1.51.42.12.21.92.00.7
Se content in liver0.10.10.20.4-0.30.20.4-0.5-0.00.20.10.0-0.4
Sr content in liver2.01.83.21.1-1.2-1.40.9-0.8-1.7-1.8-1.7-1.5-0.1
Zn content in liver2.02.33.5-1.61.61.6-1.11.01.81.81.91.4-0.5
Bone: minimum diameter1.32.36.3-1.01.21.6-1.92.00.81.00.71.52.5
Time in familiar zone, hab. session 11.21.11.8-1.31.11.1-0.60.51.31.21.30.8-0.9
Time in novel zone, hab. session 10.00.00.10.3-0.3-0.00.3-0.2-0.2-0.2-0.2-0.2-0.0
Total zone transitions, hab. session 10.10.10.2-0.0-0.10.3-0.10.1-0.4-0.5-0.4-0.40.1
Total locomotion distance, hab. session 10.20.30.90.1-0.20.5-0.30.4-0.7-0.7-0.7-0.31.0
Locomotion velocity, hab. session 10.40.61.60.5-0.5-0.1-0.10.2-1.0-1.0-1.1-0.51.3
Time in familiar zone, hab. session 20.30.30.8-0.50.50.3-0.60.60.50.50.50.60.9
Time in novel zone, hab. session 20.90.92.20.8-0.8-0.81.1-1.1-0.7-0.7-0.8-0.9-1.5
Total zone transitions, hab. session 20.81.12.50.6-0.9-0.90.6-0.5-1.4-1.6-1.4-1.30.3
Total locomotion distance, hab. session 21.41.83.51.0-1.2-1.40.8-0.8-1.7-1.9-1.8-1.60.2
Locomotion velocity, hab. session 21.01.32.90.7-1.0-1.20.5-0.5-1.6-1.7-1.6-1.40.4
Novel to familiar place preference ratio0.70.71.4-0.60.81.0-0.60.51.11.21.11.00.1
Novelty place preference1.11.21.9-0.81.01.1-0.90.81.31.41.41.30.4
Time in novel zone, NPP test1.31.42.3-0.91.11.3-0.80.81.41.51.51.30.1
Total zone transitions, NPP test0.81.12.10.8-1.0-1.10.7-0.7-1.4-1.4-1.4-1.20.0
Total locomotion distance, NPP test0.81.12.10.9-1.0-1.20.5-0.4-1.4-1.4-1.4-1.00.6
Locomotion velocity, NPP test1.21.73.11.1-1.2-1.60.6-0.5-1.7-1.8-1.7-1.30.8
Intraocular pressure0.10.10.5-0.70.50.2-0.50.50.20.10.20.1-0.2
Delta distance traveled before/after self-admin0.30.30.8-0.50.50.9-0.60.60.30.30.20.40.6
Delta ambulatory time before/after self-admin0.00.00.3-0.10.00.5-0.10.1-0.1-0.1-0.2-0.10.1
Parametrial fat weight0.20.51.3-0.20.50.5-0.30.31.11.11.01.00.2
Pavlov. Cond. lever latency1.11.43.7-1.01.01.9-0.40.31.41.51.40.9-0.9
Pavlov. Cond. magazine entry latency0.00.00.1-0.20.20.1-0.30.30.0-0.1-0.10.00.1
Pavlov. Cond. change in total contacts1.11.11.91.0-1.1-1.30.7-0.6-1.3-1.4-1.4-1.00.1
Pavlov. Cond. index score0.20.31.00.3-0.4-1.0-0.00.1-0.6-0.7-0.7-0.40.5
Pavlov. Cond. latency score0.40.51.70.5-0.5-1.30.1-0.0-0.8-0.9-0.8-0.50.5
Pavlov. Cond. lever contacts1.72.04.51.4-1.4-2.10.7-0.6-1.7-1.8-1.7-1.20.7
Pavlov. Cond. magazine entry number0.40.51.10.9-0.8-0.51.0-1.0-0.5-0.4-0.4-0.6-0.6
Pavlov. Cond. intertrial magazine entries2.53.05.82.4-2.1-1.42.0-2.0-1.7-1.5-1.5-1.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.41.10.5-0.6-1.00.2-0.2-0.8-0.9-0.8-0.60.3
Pavlov. Cond. response bias0.20.20.60.1-0.2-0.5-0.30.4-0.5-0.6-0.6-0.20.8
Pavlov. Cond. lever latency0.10.20.40.3-0.10.70.3-0.40.40.60.30.3-0.6
Pavlov. Cond. magazine entry latency0.91.11.81.2-1.2-1.00.8-0.7-1.4-1.3-1.3-1.00.3
Pavlov. Cond. change in total contacts0.20.31.9-0.20.1-0.4-0.60.7-0.4-0.5-0.1-0.01.4
Pavlov. Cond. index score0.50.71.40.6-0.7-1.00.3-0.3-1.2-1.2-1.0-0.90.5
Pavlov. Cond. latency score0.70.91.70.8-0.9-1.10.6-0.5-1.3-1.3-1.1-1.10.2
Pavlov. Cond. lever contacts0.20.30.9-0.60.4-0.3-0.80.8-0.1-0.20.10.10.9
Pavlov. Cond. magazine entry number0.10.20.4-0.30.40.4-0.20.20.60.60.50.5-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.20.4-0.10.20.1-0.10.30.40.20.50.4
Pavlov. Cond. lever-magazine prob. diff.0.50.71.50.6-0.7-1.00.3-0.3-1.2-1.2-1.0-0.90.6
Pavlov. Cond. response bias0.10.20.5-0.1-0.0-0.6-0.30.4-0.5-0.6-0.3-0.30.7
Time in closed arm before self-admin3.24.15.7-2.42.32.1-1.81.72.42.32.31.9-0.1
Time in closed arm after self-admin0.60.71.8-0.50.70.6-0.90.90.60.70.70.91.4
Time in open arm before self-admin1.11.21.41.0-1.1-1.21.1-1.1-1.1-1.2-1.1-1.1-0.7
Time in open arm after self-admin0.70.81.11.1-1.0-0.51.0-1.0-0.8-0.7-0.9-0.8-0.6
Bone: periosteal estimation0.91.83.7-1.21.31.4-1.81.90.60.70.51.21.9
Bone: periosteal perimeter0.50.92.1-0.90.80.9-1.41.40.10.10.00.61.4
Bone: post-yield work0.20.21.80.2-0.00.1-0.40.5-0.3-0.2-0.20.21.3
Progressive ratio test 1 active lever presses3.94.96.0-2.12.22.5-2.22.12.32.32.42.31.2
Progressive ratio test 1 breakpoint4.45.36.6-2.32.42.6-2.32.22.42.52.62.41.1
Progressive ratio test 1 inactive lever presses2.33.33.7-1.71.81.8-1.91.91.71.81.91.91.6
Progressive ratio test 2 active lever presses6.07.08.0-2.72.82.6-2.82.82.62.62.72.71.8
Progressive ratio test 2 breakpoint6.47.38.5-2.72.82.7-2.92.92.72.72.82.81.9
Progressive ratio test 2 inactive lever presses4.87.810.2-2.82.93.2-2.82.82.92.92.92.91.6
Incentive Sensitization - Responses4.15.87.5-2.52.62.2-2.72.72.32.32.32.51.8
Incentive Sensitization - Breakpoint4.45.77.3-2.42.52.2-2.72.72.32.32.32.51.9
Sum of active levers in priming session hrs 5-60.40.31.30.3-0.4-0.30.7-0.7-0.3-0.3-0.4-0.6-1.2
Progressive ratio0.10.10.2-0.10.20.3-0.20.20.20.30.40.30.3
Food seeking constrained by brief footshock1.92.43.0-1.21.41.6-1.51.51.61.61.61.71.5
Seeking ratio, punishment vs. effort0.10.10.2-0.40.40.4-0.40.40.30.40.20.40.3
Retroperitoneal fat weight0.31.32.1-0.81.01.1-0.90.91.41.41.41.40.6
Reaction time number correct0.61.11.61.3-1.2-0.81.1-1.1-1.0-1.0-1.2-1.0-0.4
Reaction time mean minus median0.51.21.7-1.31.11.3-0.50.41.31.21.30.7-1.1
Reaction time mean minus median AUC1.02.53.9-1.81.71.7-1.00.92.01.91.91.3-0.9
Reaction time num false alarms0.10.10.2-0.40.30.4-0.20.20.20.2-0.30.1-0.3
Reaction time num false alarms AUC0.00.10.4-0.10.00.30.0-0.0-0.1-0.1-0.6-0.2-0.4
Reaction time trials correct on left0.61.11.61.3-1.2-0.81.1-1.1-1.0-1.0-1.2-1.0-0.4
Reaction time trials on left0.61.11.71.3-1.2-0.81.1-1.1-1.0-1.0-1.2-1.0-0.4
Reaction time mean0.20.30.4-0.60.60.5-0.50.50.50.50.60.50.1
Reaction time mean AUC0.00.00.1-0.20.20.3-0.10.00.20.20.20.1-0.2
Median of all reaction times0.00.00.2-0.10.10.0-0.30.30.00.10.10.20.5
Reaction time omissions0.00.00.1-0.10.00.1-0.00.0-0.1-0.1-0.1-0.1-0.2
Reaction time false alarm rate0.10.20.4-0.60.50.6-0.40.40.30.3-0.10.2-0.2
Reaction time premature initiation rate0.91.31.71.0-1.1-1.01.1-1.1-1.3-1.2-1.1-1.3-0.9
Reaction time premature initiations1.32.42.91.5-1.6-1.31.6-1.5-1.7-1.7-1.6-1.7-1.1
Std. dev. reaction times0.30.51.0-0.90.70.9-0.20.20.80.70.70.3-1.0
Reaction time trials completed0.61.11.71.3-1.2-0.81.1-1.1-1.0-1.0-1.2-1.0-0.4
Reaction time trials AUC0.40.81.31.1-1.0-0.70.9-0.9-0.8-0.8-1.0-0.8-0.3
Run reversals in cocaine runway, females0.30.30.7-0.90.70.6-0.40.40.60.50.60.3-0.6
Run reversals in cocaine runway, males2.22.23.5-1.71.51.7-0.90.71.91.81.91.2-0.8
Latency to leave start box in cocaine runway0.40.50.70.9-0.8-0.70.7-0.7-0.5-0.6-0.8-0.6-0.1
Latency to leave start box in cocaine runway, F0.10.10.30.1-0.2-0.30.4-0.4-0.1-0.2-0.3-0.4-0.6
Latency to leave start box in cocaine runway, M1.01.01.91.4-1.2-1.10.8-0.7-1.1-1.0-1.2-0.70.5
Std. dev. time between licks in bursts0.10.10.3-0.20.0-0.6-0.20.2-0.3-0.5-0.3-0.30.2
Total sessions with >9 infusions2.22.63.4-1.61.71.7-1.81.81.51.51.61.61.4
Short access day 1 total inactive lever presses0.10.10.5-0.0-0.00.1-0.30.3-0.3-0.3-0.2-0.10.7
Short access day 10 total inactive lever presses0.20.41.0-1.00.90.5-0.80.80.60.50.60.5-0.0
Short access day 1 total infusions2.43.24.2-1.91.91.9-2.12.11.61.61.81.81.4
Short access day 10 total infusions3.54.55.1-2.12.22.2-2.22.22.12.12.32.21.5
Short access total infusions2.73.44.1-1.81.91.9-2.02.01.81.81.81.91.6
Short access day 1 locomotion0.50.60.8-0.80.80.7-0.90.90.60.60.70.70.6
Short access day 10 total locomotion2.13.95.3-2.12.12.3-2.12.11.91.92.01.91.0
Short access total locomotion3.03.64.4-2.12.12.0-2.02.01.91.92.11.90.9
One hour access (0.3 mA shock)3.94.55.9-2.42.41.9-2.42.42.02.02.02.11.4
Compulsive drug intake1.21.52.5-1.31.30.7-1.51.61.01.00.91.21.1
One hour access (shock baseline)0.91.42.2-1.51.41.2-1.21.21.21.11.31.10.4
Social response proportion0.00.00.10.1-0.1-0.00.2-0.20.00.00.2-0.0-0.3
Social responses0.20.20.8-0.90.60.4-0.50.50.40.30.30.2-0.5
Social time0.10.20.40.4-0.4-0.40.3-0.2-0.5-0.5-0.6-0.40.1
Soleus weight0.20.41.4-0.5-0.0-0.7-0.20.3-0.8-1.2-0.8-0.9-0.0
Bone: stiffness1.01.62.9-1.51.40.9-1.71.70.90.90.81.21.2
Tibialis anterior weight0.10.31.5-0.80.3-0.2-0.10.1-0.3-0.6-0.2-0.7-1.2
Time to tail flick, vehicle, before self-admin0.91.02.00.8-0.9-1.01.2-1.2-0.5-0.6-1.0-0.9-1.4
Time to tail flick, vehicle, after self-admin0.50.71.2-0.30.60.5-0.70.70.91.00.91.11.0
Time to tail flick, test, before self-admin0.10.10.5-0.30.20.60.0-0.00.30.30.40.1-0.7
Time to tail flick, test, after self-admin0.80.92.6-0.30.61.0-0.91.00.70.80.81.11.6
Delta time to tail flick, vehicle, before/after SA2.12.02.6-1.11.31.5-1.51.51.31.41.61.61.5
Delta time to tail flick, test, before/after SA0.40.42.30.6-0.4-0.7-0.10.2-0.5-0.4-0.40.01.5
Tibia length0.82.34.0-1.31.41.7-1.81.91.11.01.01.42.0
Ambulatory time before self-admin2.64.05.2-2.32.21.8-2.12.12.22.11.92.01.0
Ambulatory time after self-admin3.94.66.0-2.42.42.4-2.32.32.12.11.92.11.1
Bone: tissue strength0.10.20.8-0.30.20.2-0.50.5-0.0-0.00.00.20.9
Total heroin consumption0.30.40.7-0.80.70.6-0.40.40.70.60.80.4-0.4
Bone: trabecular number0.20.30.70.3-0.5-0.80.3-0.3-0.8-0.8-0.7-0.7-0.2
Bone: trabecular spacing0.00.00.10.4-0.20.00.4-0.40.00.10.10.0-0.1
Bone: trabecular thickness0.91.11.5-1.11.11.2-1.21.21.01.00.91.10.7
Bone: trabecular tissue density0.50.71.1-0.70.81.0-0.80.80.80.90.90.90.7
Water consumed over 24 hours0.00.00.10.1-0.00.1-0.00.00.00.10.00.10.2
Number of responses in last shaping day0.70.81.1-0.90.90.6-1.01.10.80.80.91.00.9