Usf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Usf2 0.02 0.02 6.9e-03 0 0 0.03 -0 7.2e-02 3.3e-01 1.9e-04 4.3e-01
2 BLA gene expression Usf2 0.09 0.06 6.6e-04 0.04 0.05 0.05 0.05 3.3e-03 1.8e-03 1.6e-03 1.6e-03
3 Brain gene expression Usf2 0.13 0.07 6.2e-07 0.07 0.07 0.07 0.07 2.6e-07 4.3e-07 5.1e-07 2.2e-07
4 PL gene expression Usf2 0.07 0.05 1.1e-03 0.04 0.04 0.04 0.03 7.3e-05 8.5e-05 8.9e-05 1.3e-04
5 Liver alternative TSS NM_031139.1 0.14 0.07 2.8e-07 0.08 0.06 0.07 0.08 3.3e-09 2.3e-07 2.6e-08 6.0e-09
6 Liver alternative TSS XM_039092335.1 0.15 0.08 3.1e-07 0.08 0.06 0.07 0.07 5.9e-09 3.7e-07 4.2e-08 1.5e-08
7 PL alternative polyA NM_031139.1 0.06 0.04 5.5e-08 0.07 0.07 0.07 0.07 3.8e-08 2.7e-08 1.7e-08 1.8e-08
8 PL alternative polyA XM_039092335.1 0.06 0.03 4.8e-08 0.04 0.07 0.07 0.06 3.1e-05 9.9e-08 4.3e-08 1.1e-07
9 Brain alternative polyA NM_031139.1 0.1 0.06 2.8e-13 0.16 0.14 0.13 0.15 1.4e-14 3.1e-13 3.3e-12 6.3e-14
10 Brain alternative polyA XM_039092335.1 0.1 0.06 3.7e-13 0.16 0.14 0.13 0.15 2.1e-14 4.4e-13 8.4e-12 1.2e-13
11 NAcc alternative polyA NM_031139.1 0.03 0.02 1.8e-04 0.02 0.03 0.03 0.03 4.6e-03 2.0e-04 2.3e-04 6.2e-04
12 NAcc isoform ratio XM_039092335.1 0.04 0.03 6.5e-04 0.03 0.03 0.01 0.02 4.1e-04 4.8e-04 7.7e-03 1.1e-03
13 NAcc isoform ratio NM_031139.1 0.05 0.04 9.7e-05 0.04 0.04 0.02 0.04 4.4e-05 4.6e-05 1.8e-03 3.4e-05
14 LHb isoform ratio NM_031139.1 0.11 0.08 2.9e-03 0.07 0.04 0.02 0.03 7.7e-03 5.0e-02 1.0e-01 5.8e-02
15 LHb isoform ratio XM_039092335.1 0.12 0.08 1.6e-03 0.07 0.03 0.03 0.03 7.6e-03 5.7e-02 8.1e-02 6.6e-02
16 Adipose mRNA stability Usf2 0.03 0.02 1.1e-04 0.03 0.02 0.01 0.03 2.3e-04 1.5e-03 3.0e-02 6.7e-04
17 NAcc alternative polyA XM_039092335.1 0.03 0.02 3.6e-05 0.04 0.04 0.04 0.04 4.4e-05 5.7e-05 4.8e-05 5.7e-05
18 Brain mRNA stability Usf2 0.03 0.03 4.3e-03 0.01 0.02 0 0.01 2.0e-02 1.0e-02 1.8e-01 4.9e-02
19 NAcc mRNA stability Usf2 0.02 0.02 3.5e-03 0.02 0.02 0.02 0.02 1.3e-03 1.0e-03 1.4e-03 1.9e-03
20 OFC isoform ratio NM_031139.1 0.27 0.14 4.3e-04 0.04 0.13 0.14 0.14 5.3e-02 4.8e-04 4.0e-04 3.2e-04
21 OFC isoform ratio XM_039092335.1 0.23 0.13 6.2e-04 0.06 0.13 0.13 0.12 1.7e-02 6.2e-04 4.6e-04 7.0e-04
22 Liver alternative polyA XM_039092335.1 0.04 0.03 2.2e-03 0 0 -0 0 1.0e-01 1.8e-01 8.0e-01 2.3e-01
23 NAcc alternative TSS NM_031139.1 0.05 0.04 1.9e-03 0.03 0.03 0.03 0.03 1.7e-04 2.3e-04 3.8e-04 2.8e-04
24 OFC alternative TSS XM_039092335.1 0.33 0.17 8.1e-03 0.11 0.02 0.03 0.08 1.5e-03 1.1e-01 7.2e-02 5.4e-03
25 LHb alternative TSS XM_039092335.1 0.27 0.15 1.8e-03 0.05 0.05 0.04 0.08 2.2e-02 2.8e-02 4.8e-02 6.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.01.72.81.0-1.41.2-1.2-0.60.6-1.61.6-1.51.51.71.51.5-1.41.41.51.5-1.5-1.51.11.11.7-0.10.2-0.6
Area under the delay curve0.40.41.4-0.9-0.10.2-0.2-1.11.1-0.00.00.2-0.2-0.1-0.2-0.20.2-0.2-0.3-0.90.60.6-0.8-0.8-0.81.2-1.21.0
BMI with tail0.10.31.71.30.2-0.60.8-0.10.10.5-0.50.6-0.6-0.6-0.5-0.50.7-0.7-0.5-0.50.40.4-0.2-0.2-0.90.1-0.20.4
BMI without tail0.10.23.61.9-0.2-0.00.0-0.10.10.2-0.2-0.10.1-0.2-0.3-0.30.0-0.0-0.00.30.10.0-0.0-0.00.2-0.10.1-0.1
Body weight1.66.714.20.9-3.73.8-3.6-2.52.5-3.33.3-2.72.73.52.62.6-2.62.62.62.6-2.0-2.00.90.72.81.9-2.00.5
Weight adjusted by age0.20.20.6-0.6-0.80.5-0.6-0.30.3-0.60.6-0.40.40.40.20.2-0.30.30.60.6-0.2-0.1-0.0-0.00.50.3-0.30.1
Bone surface0.71.23.50.2-1.41.9-1.9-1.91.9-1.21.2-0.90.91.30.60.6-0.80.81.00.8-0.3-0.2-0.4-0.40.91.3-1.20.7
Bone volume0.91.53.80.3-1.62.0-1.9-1.71.7-1.61.6-1.21.21.71.01.0-1.11.11.31.1-0.8-0.70.10.01.30.9-0.90.3
Breakpoint value in progressive ratio session0.60.74.3-2.1-0.70.8-0.6-1.31.3-0.60.5-0.10.10.50.30.3-0.10.10.10.00.20.3-0.6-0.6-0.81.4-1.41.1
Number of licking bursts3.03.56.6-1.02.2-1.71.70.0-0.02.3-2.32.5-2.5-2.3-2.0-2.02.1-2.1-2.6-2.42.12.0-1.5-1.4-2.20.2-0.21.0
Context. condit. distance diff. score0.60.81.9-0.7-0.30.1-0.1-0.50.50.5-0.60.6-0.6-0.6-1.1-1.10.6-0.6-0.7-0.81.11.2-1.3-1.4-0.91.2-1.21.3
Locomotion velocity, session 10.40.52.0-1.20.6-0.60.50.5-0.50.1-0.1-0.10.10.00.30.3-0.10.10.20.2-0.6-0.50.90.90.5-1.41.4-1.2
Locomotion distance, session 10.81.15.8-2.4-0.51.1-1.0-2.32.3-0.20.20.4-0.40.2-0.7-0.70.3-0.3-0.5-0.30.70.9-1.2-1.2-0.01.0-1.00.9
Locomotion velocity, session 20.70.83.0-1.01.7-1.11.10.0-0.01.1-1.11.1-1.1-1.0-0.7-0.70.9-0.9-1.0-1.10.50.50.00.1-0.4-1.01.0-0.4
Locomotion distance, session 22.12.96.2-2.51.7-1.01.2-1.71.71.6-1.61.9-1.9-1.7-2.0-2.01.9-1.9-2.0-2.11.92.1-1.6-1.5-1.70.2-0.20.9
Locomotion velocity, session 30.50.51.2-0.50.9-0.40.4-0.70.70.8-0.80.7-0.7-0.8-1.1-1.11.0-1.0-0.8-0.90.80.9-0.7-0.6-0.3-0.30.30.2
Locomotion distance, session 32.72.912.5-1.5-1.01.7-1.6-3.53.5-0.10.10.6-0.60.2-1.1-1.10.7-0.7-0.9-1.01.51.6-2.2-2.3-0.62.5-2.52.3
Stereotopy head waving bouts, day 31.92.35.52.30.5-1.01.12.3-2.3-0.40.4-1.11.10.21.21.2-0.80.81.01.0-1.5-1.62.12.10.9-2.22.2-2.2
Stereotopy head waving duration, day 32.02.47.51.70.8-1.51.62.7-2.7-0.10.2-0.80.8-0.11.01.0-0.70.70.81.0-1.4-1.42.12.10.6-2.42.4-2.3
Locomotion velocity, session 70.80.96.7-2.6-0.40.7-0.7-1.51.5-0.00.00.5-0.50.2-0.3-0.30.3-0.3-0.5-0.70.60.8-0.9-1.0-0.51.4-1.41.2
Locomotion distance, session 70.30.44.2-2.1-0.40.7-0.7-1.21.2-0.10.10.1-0.10.4-0.2-0.20.1-0.1-0.1-0.00.20.3-0.5-0.50.30.6-0.60.5
Stereotopy head waving bouts, day 71.82.14.3-0.11.6-1.21.10.1-0.11.7-1.71.8-1.8-1.8-1.5-1.51.9-1.9-2.1-1.71.61.5-1.2-1.1-1.50.3-0.31.0
Stereotopy head waving duration, day 71.11.43.20.81.5-1.81.81.1-1.11.4-1.41.2-1.2-1.6-0.9-0.91.4-1.4-1.5-1.20.90.8-0.2-0.2-1.3-0.70.7-0.0
Locomotion velocity, session 83.23.96.3-2.22.2-2.22.00.3-0.32.5-2.52.1-2.1-2.5-2.3-2.32.3-2.3-2.2-2.42.12.2-1.5-1.5-2.3-0.20.20.7
Locomotion distance, session 83.14.58.4-2.91.2-0.70.7-1.61.61.9-1.92.2-2.2-2.0-2.7-2.72.3-2.3-2.4-2.32.72.8-2.6-2.6-2.11.3-1.32.0
Degree of sensitization distance1.01.04.4-0.30.4-0.50.42.1-2.1-0.10.1-0.70.70.30.90.9-0.80.80.80.9-1.1-1.11.31.30.8-1.21.2-1.3
Degree of sensitization stereotypy2.93.16.0-0.41.7-1.31.1-0.10.12.0-2.02.3-2.3-2.1-2.0-2.02.4-2.4-2.4-2.12.11.9-1.6-1.6-1.90.7-0.71.5
Conditioned locomotion0.40.52.61.60.8-0.91.10.2-0.20.7-0.70.6-0.6-0.9-0.6-0.60.5-0.5-0.6-0.60.50.5-0.3-0.2-1.1-0.40.4-0.1
Cocaine response after cond. corrected1.61.84.02.0-0.3-0.50.31.7-1.7-0.80.8-1.21.20.71.41.4-1.31.31.11.0-1.6-1.81.81.81.0-1.41.4-1.7
Cocaine response after cond. not corrected2.32.54.82.1-0.2-0.40.22.2-2.2-0.80.8-1.41.40.81.41.4-1.41.41.21.3-1.9-2.02.12.11.6-2.01.9-2.1
Cocaine response before conditioning0.20.31.8-1.2-0.11.2-1.4-0.20.2-0.20.2-0.10.10.5-0.1-0.10.1-0.1-0.00.30.10.0-0.3-0.31.10.2-0.30.2
Saline control response0.10.20.70.4-0.10.0-0.10.1-0.1-0.20.2-0.30.30.20.20.2-0.40.40.30.6-0.4-0.40.60.50.5-0.80.8-0.8
Bone: connectivity density0.10.20.50.1-0.30.5-0.6-0.70.7-0.50.5-0.40.40.60.50.5-0.40.40.50.5-0.5-0.40.30.30.70.2-0.1-0.0
Bone: cortical apparent density0.70.91.8-1.21.1-1.21.3-0.10.11.1-1.10.9-0.9-1.2-1.2-1.20.8-0.8-1.0-1.20.81.0-0.6-0.6-1.3-0.00.10.3
Bone: cortical area0.81.22.50.2-1.41.5-1.5-0.80.8-1.31.3-1.61.61.30.80.8-1.41.41.61.1-0.8-0.70.30.21.30.4-0.4-0.3
Bone: cortical porosity3.94.39.0-1.92.6-1.61.6-0.20.22.6-2.62.4-2.4-2.5-2.4-2.42.1-2.1-2.5-3.02.42.4-1.8-1.8-2.20.4-0.41.1
Bone: cortical porosity4.54.910.6-2.02.7-1.71.7-0.40.42.7-2.72.6-2.6-2.6-2.5-2.52.2-2.2-2.7-3.32.62.5-2.0-1.9-2.40.5-0.51.3
Bone: cortical thickness0.50.82.00.7-0.80.7-0.7-0.00.0-0.91.0-1.41.40.90.80.8-1.21.21.40.8-0.9-0.90.70.71.2-0.30.3-0.7
Bone: cortical thickness0.40.41.70.80.4-0.80.90.5-0.50.00.0-0.60.6-0.20.20.2-0.30.30.60.2-0.5-0.40.80.90.2-1.31.3-1.2
Bone: cortical tissue density0.81.12.1-1.31.2-1.31.5-0.00.01.3-1.31.0-1.0-1.3-1.3-1.30.9-0.9-1.1-1.40.91.1-0.6-0.6-1.4-0.10.10.3
Condit. Reinf. active minus inactive responses0.10.10.50.10.3-0.50.7-0.20.20.2-0.20.4-0.4-0.4-0.3-0.30.3-0.3-0.4-0.40.10.2-0.0-0.0-0.4-0.20.2-0.1
Condit. Reinf. active-inactive response ratio0.90.92.61.6-0.2-0.60.80.9-0.9-0.60.6-0.80.80.30.80.8-0.90.90.70.9-1.2-1.11.41.40.5-1.21.2-1.4
Condit. Reinf. active responses1.01.23.1-0.51.3-1.51.7-0.20.21.2-1.21.3-1.3-1.4-1.1-1.11.1-1.1-1.4-1.60.91.0-0.5-0.4-1.6-0.40.40.1
Condit. Reinf. inactive responses2.63.06.3-2.31.7-1.41.5-1.01.01.9-1.92.1-2.1-1.8-1.8-1.81.8-1.8-2.1-2.51.82.0-1.5-1.4-2.30.4-0.41.1
Incentive salience index mean0.20.30.7-0.60.6-0.50.8-0.50.50.4-0.40.6-0.6-0.6-0.6-0.60.5-0.5-0.7-0.80.40.5-0.3-0.3-0.7-0.00.00.2
Condit. Reinf. lever presses0.30.41.6-1.20.6-0.20.4-0.80.80.4-0.40.5-0.5-0.4-0.5-0.50.4-0.4-0.7-1.20.60.7-0.6-0.6-0.90.4-0.40.5
Condit. Reinf. active minus inactive responses0.30.41.1-0.7-0.91.0-1.1-1.01.0-0.70.7-0.50.50.80.20.2-0.50.50.70.4-0.2-0.0-0.2-0.20.70.5-0.40.2
Condit. Reinf. active-inactive response ratio0.00.00.1-0.2-0.1-0.10.10.2-0.20.1-0.0-0.20.2-0.1-0.3-0.3-0.20.20.3-0.20.10.2-0.2-0.10.0-0.20.3-0.3
Condit. Reinf. active responses0.81.13.9-1.5-1.21.9-1.9-2.02.0-0.90.9-0.40.41.20.30.3-0.40.40.50.5-0.00.1-0.6-0.70.91.3-1.30.9
Condit. Reinf. inactive responses1.21.55.3-1.7-0.61.9-1.9-2.32.3-0.40.40.3-0.30.7-0.0-0.00.3-0.3-0.3-0.10.60.6-1.2-1.30.22.0-2.11.8
Condit. Reinf. lever presses2.43.28.5-0.7-2.62.9-2.9-2.02.0-2.32.3-1.51.52.41.51.5-1.61.61.62.1-1.2-1.10.20.22.21.3-1.30.4
Condit. Reinf. lever reinforcers received1.01.55.4-1.8-1.22.0-2.1-2.32.3-0.80.8-0.20.21.0-0.0-0.0-0.10.10.20.20.30.4-1.1-1.10.71.7-1.61.3
Conditioned reinforcement - actives0.60.63.8-2.01.2-0.50.3-0.10.10.9-0.90.8-0.8-0.6-0.7-0.70.9-0.9-0.9-1.30.60.5-0.4-0.3-0.3-0.20.20.2
Conditioned reinforcement - inactives3.43.810.5-3.20.60.4-0.3-2.22.21.1-1.11.9-1.9-1.0-2.0-2.02.0-2.0-1.5-2.12.12.3-2.6-2.6-1.92.1-2.12.5
Conditioned locomotion2.32.87.2-2.22.3-1.71.7-0.10.12.0-2.01.8-1.8-1.9-1.7-1.71.8-1.8-1.9-2.71.61.6-1.2-1.1-2.3-0.20.20.5
Patch foraging indifference point 0 sec0.20.30.70.40.30.1-0.1-0.30.30.4-0.50.8-0.8-0.5-0.6-0.60.8-0.8-0.8-0.50.60.5-0.6-0.6-0.20.3-0.20.5
Patch foraging indifference point AUC0.20.30.90.10.6-0.80.70.9-0.90.3-0.30.0-0.0-0.20.20.2-0.10.10.1-0.3-0.4-0.40.70.7-0.0-0.80.7-0.7
Delay disc. indifference point, 0s delay1.51.64.0-2.0-0.30.4-0.2-2.02.00.1-0.10.7-0.7-0.2-0.7-0.70.7-0.7-0.8-1.41.11.4-1.6-1.6-1.72.0-2.01.9
Delay disc. indifference point, 16s delay0.40.41.4-0.5-0.20.2-0.3-1.11.1-0.10.10.1-0.10.00.20.20.1-0.1-0.3-0.90.50.5-0.7-0.7-0.91.2-1.11.0
Delay disc. indifference point, 2s delay1.11.24.3-1.7-1.01.1-1.1-2.02.0-0.80.80.0-0.00.70.10.10.0-0.0-0.1-0.30.30.5-1.0-1.0-0.42.0-2.11.7
Delay disc. indifference point, 24s delay0.90.92.5-1.5-1.21.4-1.2-1.61.6-0.90.9-0.50.50.90.60.6-0.50.50.4-0.2-0.00.1-0.6-0.6-0.11.5-1.41.0
Delay disc. indifference point, 4s delay1.11.12.7-1.51.0-0.60.5-0.50.51.0-1.01.2-1.2-1.0-1.1-1.11.2-1.2-1.2-1.71.21.2-1.1-1.1-1.10.6-0.50.9
Delay disc. indifference point, 8s delay0.10.10.6-0.4-0.00.3-0.3-0.50.50.0-0.10.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.50.40.3-0.4-0.4-0.10.7-0.80.6
Indifference point function ln k0.20.31.40.0-0.80.8-0.7-1.21.2-0.50.5-0.00.00.2-0.4-0.40.1-0.10.00.70.30.4-0.6-0.50.40.3-0.30.3
Indifference point function log k0.20.31.40.0-0.80.8-0.7-1.21.2-0.50.5-0.00.00.2-0.4-0.40.1-0.10.00.70.30.4-0.6-0.50.40.3-0.30.3
Patch foraging total patch changes 0 sec0.20.30.60.20.20.3-0.3-0.40.40.4-0.40.8-0.8-0.3-0.5-0.50.8-0.8-0.8-0.50.60.5-0.7-0.7-0.20.5-0.40.7
Patch foraging total patch changes 12 sec0.20.20.9-0.20.7-0.60.60.9-0.90.4-0.40.2-0.2-0.30.00.0-0.00.0-0.1-0.5-0.1-0.20.50.50.1-0.60.6-0.5
Patch foraging total patch changes 18 sec0.40.51.20.30.50.0-0.2-0.20.20.8-0.80.9-0.9-0.6-0.6-0.60.8-0.8-0.8-1.10.80.6-0.8-0.8-0.60.7-0.60.9
Patch foraging total patch changes 24 sec0.60.72.9-0.4-0.61.2-1.2-1.21.2-0.20.10.3-0.30.5-0.0-0.00.2-0.2-0.4-0.40.40.3-0.9-1.0-0.21.7-1.71.5
Patch foraging total patch changes 6 sec0.10.10.3-0.60.5-0.20.10.5-0.50.4-0.40.5-0.5-0.20.00.00.5-0.5-0.3-0.30.0-0.10.10.10.0-0.30.3-0.1
Patch foraging time to switch 0 sec0.81.25.12.21.1-1.21.12.0-2.00.4-0.4-0.70.7-0.30.80.8-0.70.70.50.0-0.7-0.91.31.3-0.0-1.31.3-1.3
Patch foraging water rate 0 sec0.71.25.9-2.40.9-1.01.0-0.50.50.9-0.91.4-1.4-1.0-1.3-1.31.4-1.4-1.3-0.90.91.2-0.7-0.7-1.0-0.30.20.3
Patch foraging water rate 12 sec1.21.88.8-3.0-0.01.0-1.3-1.51.50.6-0.71.5-1.5-0.3-1.2-1.21.3-1.3-1.5-0.51.41.3-1.7-1.70.11.3-1.21.6
Patch foraging water rate 18 sec0.50.75.0-2.20.8-0.70.5-0.20.20.8-0.81.0-1.0-0.7-0.8-0.81.1-1.1-1.1-0.40.60.7-0.4-0.4-0.3-0.40.40.1
Patch foraging water rate 24 sec4.15.717.7-4.20.60.2-0.2-2.62.61.5-1.52.7-2.7-1.5-2.5-2.52.7-2.7-2.6-1.82.72.9-2.8-2.8-1.82.0-2.12.7
Patch foraging water rate 6 sec1.72.49.3-3.1-0.61.3-1.4-2.52.50.2-0.21.3-1.30.0-1.2-1.21.3-1.3-1.2-0.61.31.5-1.9-2.0-0.51.9-1.92.1
Seeking ratio, delayed vs. immediate footshock1.21.45.9-2.4-0.61.3-1.3-2.02.0-0.20.20.4-0.40.3-0.3-0.30.4-0.4-0.5-0.60.91.0-1.3-1.3-0.51.9-1.81.7
Distance traveled before self-admin0.00.00.2-0.40.50.0-0.00.2-0.20.2-0.20.1-0.1-0.00.10.10.1-0.1-0.2-0.2-0.0-0.10.20.20.20.0-0.00.0
Distance traveled after self-admin0.91.03.9-1.0-1.02.0-1.9-1.61.6-0.80.7-0.40.41.00.30.3-0.40.40.30.20.20.1-0.6-0.70.71.6-1.61.2
Extensor digitorum longus weight1.14.29.03.0-1.80.20.21.1-1.1-2.22.2-2.42.41.62.42.4-2.42.42.42.1-2.4-2.22.42.41.0-1.61.5-2.2
Bone: elastic displacement0.20.30.70.70.2-0.00.00.8-0.8-0.20.2-0.20.20.30.60.6-0.20.20.30.3-0.6-0.70.70.80.8-0.60.5-0.5
Bone: elastic work1.01.32.7-0.0-1.41.5-1.4-0.50.5-1.51.5-1.31.31.61.41.4-1.31.31.21.1-1.2-1.20.70.71.40.5-0.5-0.1
Bone: endosteal estimation0.41.03.5-0.4-1.41.8-1.9-1.61.6-1.11.1-0.50.51.10.30.3-0.50.50.71.0-0.1-0.1-0.5-0.51.01.0-1.00.6
Bone: endosteal perimeter0.40.93.2-0.6-1.11.6-1.7-1.81.8-0.70.6-0.30.30.7-0.0-0.0-0.30.30.40.60.30.3-0.9-1.00.51.3-1.31.0
Epididymis fat weight0.20.41.7-0.8-0.30.7-0.6-1.31.3-0.20.20.1-0.10.3-0.1-0.10.1-0.10.1-0.10.20.3-0.5-0.50.21.0-1.10.9
Delta time in closed arm before/after self-admin2.32.25.40.1-2.31.9-1.8-0.80.8-2.12.1-1.71.71.91.61.6-1.71.71.81.6-1.3-1.20.60.61.40.6-0.6-0.2
Delta time in open arm before/after self-admin0.60.61.40.71.2-1.00.90.9-0.91.1-1.10.7-0.7-1.0-1.0-1.00.7-0.7-0.7-0.70.50.4-0.1-0.1-0.1-0.80.8-0.3
Diff in mean of infusions in LGA sessions0.80.92.6-0.50.7-0.91.0-0.20.21.1-1.11.1-1.1-1.2-1.0-1.01.1-1.1-1.1-0.91.11.1-0.8-0.8-1.60.3-0.30.7
Delay discount exponential model param0.30.31.20.70.2-0.30.31.0-1.00.1-0.1-0.10.10.00.20.2-0.10.10.20.7-0.5-0.50.70.70.6-1.11.1-0.9
Extinction: sum of active levers before priming3.33.36.00.3-2.21.9-1.8-0.50.5-2.42.4-2.22.22.42.42.4-2.22.22.12.2-1.9-1.91.11.11.60.6-0.6-0.4
Active lever presses in extinction session 65.04.98.31.0-1.71.3-1.40.8-0.8-2.42.4-2.72.72.52.92.9-2.72.72.72.1-2.7-2.72.52.42.5-0.80.8-1.7
Bone: final force0.81.33.40.1-1.81.7-1.6-1.31.3-1.51.5-1.31.31.40.80.8-1.01.01.40.9-0.6-0.5-0.1-0.10.81.2-1.20.6
Bone: final moment1.11.74.40.0-2.12.0-1.9-1.41.4-1.71.7-1.51.51.71.01.0-1.21.21.61.0-0.8-0.60.0-0.01.11.3-1.30.6
Food consumed during 24 hour testing period1.11.42.8-1.6-0.10.8-0.8-1.71.70.4-0.41.1-1.1-0.3-1.0-1.00.8-0.8-1.0-0.61.31.2-1.6-1.6-0.51.7-1.71.7
Glucose0.30.41.90.50.2-0.30.11.4-1.40.0-0.0-0.40.40.10.40.4-0.60.60.30.4-0.5-0.70.80.80.8-0.70.7-0.8
Heart weight0.60.86.7-2.6-0.50.4-0.5-0.80.80.0-0.00.7-0.7-0.0-0.7-0.70.7-0.7-0.5-0.60.70.9-1.1-1.1-0.61.1-1.11.2
Delay discount hyperbolic model param0.40.41.40.90.2-0.30.21.0-1.00.1-0.1-0.10.1-0.00.10.1-0.10.10.20.7-0.5-0.50.70.80.7-1.21.1-1.0
Intermittent access intake day 1-15 change1.41.43.70.3-1.71.9-1.8-1.01.0-1.61.6-1.11.11.61.11.1-1.11.11.31.2-0.7-0.70.0-0.01.01.1-1.10.5
Intermittent access intake escalation1.31.33.70.1-1.71.9-1.8-1.31.3-1.51.5-1.01.01.51.01.0-0.90.91.21.0-0.6-0.5-0.2-0.20.81.3-1.30.7
Intermittent access intake escalation 20.80.81.80.7-1.21.3-1.3-0.30.3-1.11.1-1.01.01.11.01.0-0.90.91.10.9-0.7-0.70.30.31.00.5-0.50.0
Intermitt. access day 1 inactive lever presses1.11.12.6-0.7-1.61.4-1.3-0.80.8-1.51.5-1.11.11.41.21.2-1.01.01.30.8-0.8-0.70.30.20.61.0-1.00.4
Intermitt. access day 15 inactive lever presses0.40.41.4-1.2-0.40.3-0.2-1.01.0-0.20.20.3-0.30.0-0.1-0.10.2-0.2-0.0-0.60.40.6-0.7-0.7-1.01.0-1.00.9
Intermitt. access escalation Index1.11.01.90.60.2-0.10.1-0.80.80.9-0.91.3-1.3-0.7-1.4-1.41.4-1.4-0.8-0.71.11.1-1.4-1.3-1.00.7-0.71.1
Intermittent access day 1 total infusions5.15.99.7-2.62.4-1.51.4-0.80.82.8-2.83.0-3.0-2.6-3.0-3.02.9-2.9-2.9-3.12.82.7-2.4-2.4-2.60.5-0.51.6
Intermittent access day 15 total infusions3.33.76.2-2.30.90.1-0.1-1.81.81.5-1.52.2-2.2-1.3-2.1-2.12.2-2.2-1.9-2.22.22.2-2.5-2.5-1.91.6-1.72.2
Intermittent access terminal intake (last 3 days)4.14.56.8-2.11.4-0.40.4-1.51.52.0-2.02.6-2.6-1.9-2.5-2.52.6-2.6-2.4-2.42.62.6-2.6-2.6-2.11.2-1.32.0
Intermittent access total infusions4.95.58.7-2.11.8-0.70.5-1.31.32.5-2.52.9-2.9-2.2-2.9-2.92.9-2.9-2.7-2.72.92.8-2.8-2.7-2.21.1-1.12.0
Intermittent access day 1 locomotion4.85.19.3-3.12.0-1.11.1-1.41.42.4-2.42.6-2.6-2.1-2.5-2.52.6-2.6-2.5-2.92.52.5-2.4-2.4-2.61.1-1.11.9
Intermittent access day 15 total locomotion3.63.89.6-3.10.80.1-0.1-1.91.91.4-1.42.3-2.3-1.1-2.1-2.12.2-2.2-1.9-2.12.02.1-2.5-2.5-1.81.8-1.72.3
Intermittent access total locomotion3.54.07.3-2.52.0-1.21.2-0.90.92.2-2.32.5-2.5-2.0-2.3-2.32.5-2.5-2.3-2.72.12.1-2.0-1.9-2.20.7-0.71.5
Intermittent access standard deviation1.61.75.6-0.7-1.62.4-2.3-2.22.2-0.90.8-0.10.11.00.20.2-0.10.10.3-0.20.60.5-1.3-1.30.32.2-2.31.8
Left kidney weight3.610.117.20.9-3.63.2-3.2-0.70.7-4.04.1-3.93.94.13.93.9-4.14.13.53.3-3.5-3.42.52.33.40.7-0.8-1.0
Right kidney weight4.312.021.81.0-4.24.1-4.0-1.31.3-4.54.5-4.04.04.74.14.1-4.04.03.83.7-3.5-3.42.42.23.91.2-1.3-0.6
Cocaine induced anxiety0.91.01.80.4-1.20.6-0.5-0.00.0-1.31.3-1.31.31.31.31.3-1.31.30.71.0-1.3-1.20.90.90.7-0.00.0-0.5
Post-drug Anxiety0.70.81.40.9-0.1-0.60.71.2-1.2-0.50.5-1.01.00.51.01.0-1.01.00.10.5-1.1-1.11.11.20.0-0.80.8-1.1
Baseline Anxiety1.11.12.30.11.5-1.41.40.7-0.71.4-1.41.1-1.1-1.5-1.2-1.21.1-1.1-0.8-1.51.11.0-0.6-0.5-1.3-0.30.30.2
Tail length2.05.913.80.1-3.13.6-3.7-1.71.7-2.92.9-2.72.73.32.32.3-2.82.82.52.8-1.9-2.00.90.83.41.2-1.2-0.1
Length with tail3.512.931.8-1.0-4.95.6-5.6-3.53.5-4.54.5-3.53.54.93.43.4-3.63.63.53.5-2.5-2.40.70.64.22.9-2.90.9
Length without tail2.86.115.4-1.9-3.53.9-3.8-2.92.9-3.23.2-1.91.93.42.32.3-1.91.92.11.9-1.5-1.30.20.12.22.6-2.71.3
Times rat made contact with spout0.40.51.30.3-0.2-0.20.21.1-1.1-0.30.3-0.20.20.30.50.5-0.50.50.21.0-0.8-0.81.01.00.9-1.11.1-1.1
Lifetime Intake3.33.76.7-1.71.6-0.70.6-0.90.92.1-2.12.4-2.4-1.9-2.6-2.62.4-2.4-2.1-2.22.32.3-2.2-2.2-1.70.6-0.61.4
Liver weight, left0.61.02.51.6-0.0-0.60.81.0-1.0-0.50.5-0.90.90.30.90.9-1.11.10.70.7-1.1-1.11.51.50.7-1.21.2-1.4
Liver weight, right0.20.31.2-0.30.7-0.60.70.5-0.5-0.00.0-0.00.00.00.20.2-0.20.2-0.0-0.1-0.6-0.51.11.10.5-1.11.0-1.0
Locomotor activity0.81.35.10.30.8-1.11.01.8-1.80.1-0.10.0-0.0-0.00.50.5-0.20.20.00.7-1.0-1.11.61.61.1-2.32.2-1.9
Locomotor testing distance0.40.72.9-0.31.0-0.80.71.5-1.50.6-0.60.5-0.5-0.4-0.1-0.10.2-0.2-0.40.3-0.3-0.40.80.80.7-1.71.6-1.3
Locomotor testing rearing0.81.33.0-0.81.7-1.41.30.9-0.91.5-1.51.4-1.4-1.4-1.3-1.31.2-1.2-1.3-0.70.80.8-0.2-0.1-0.4-1.41.3-0.6
Locomotion in novel chamber0.30.41.81.30.6-0.91.01.1-1.10.4-0.40.2-0.2-0.5-0.4-0.40.1-0.10.10.1-0.2-0.20.40.4-0.0-1.11.0-0.9
Locomotion in novel chamber post-restriction0.10.10.4-0.00.5-0.20.40.6-0.60.0-0.1-0.00.0-0.10.20.2-0.10.10.00.4-0.3-0.20.50.5-0.2-0.60.5-0.6
Fecal boli incidents, locomotor time 11.11.24.20.11.8-1.92.11.6-1.61.0-1.00.3-0.3-1.1-0.1-0.10.3-0.3-0.4-1.1-0.1-0.10.90.9-0.8-1.71.7-1.2
Change in fecal boli incidents, locomotor task1.71.72.60.6-0.60.1-0.01.2-1.2-1.11.1-1.51.51.01.41.4-1.51.51.41.5-1.6-1.61.61.61.1-1.21.2-1.6
Time >=10cm from walls, locomotor time 10.10.11.51.2-0.1-0.20.30.2-0.20.0-0.0-0.30.3-0.10.10.1-0.30.30.30.3-0.1-0.00.20.20.0-0.40.4-0.4
Bouts of movement, locomotor time 11.71.99.7-3.10.10.6-0.6-1.81.80.4-0.51.1-1.1-0.3-0.9-0.91.1-1.1-1.2-1.21.21.3-1.6-1.7-1.01.8-1.91.9
Total resting periods, locomotor time 11.11.36.5-2.50.20.4-0.5-1.41.40.4-0.50.9-0.9-0.2-0.7-0.70.9-0.9-1.0-1.11.01.0-1.3-1.4-0.81.5-1.51.6
Rest time, locomotor task time 10.60.72.3-0.70.9-1.41.51.2-1.20.3-0.3-0.20.2-0.40.50.5-0.20.20.0-0.6-0.6-0.50.91.0-0.7-1.21.2-1.1
Distance moved, locomotor task time 10.30.30.80.0-0.70.6-0.9-0.90.9-0.10.10.4-0.4-0.0-0.6-0.60.4-0.4-0.20.50.60.6-0.8-0.80.20.9-0.90.9
Vertical activity count, locomotor time 10.80.83.2-0.7-1.11.5-1.8-1.41.4-0.60.60.1-0.10.7-0.1-0.10.1-0.10.00.50.40.3-0.8-0.90.61.5-1.51.3
Time >=10cm from walls, locomotor time 21.11.23.0-1.01.6-1.61.70.6-0.61.4-1.41.0-1.0-1.5-1.1-1.11.0-1.0-1.0-1.30.80.9-0.3-0.2-1.2-0.80.7-0.2
Bouts of movement, locomotor time 20.50.61.6-1.30.50.0-0.1-0.40.40.7-0.71.0-1.0-0.6-0.8-0.81.0-1.0-0.9-0.60.90.8-0.8-0.8-0.10.4-0.50.8
Total resting periods, locomotor time 20.50.61.4-1.20.8-0.30.2-0.00.00.9-0.91.1-1.1-0.8-0.9-0.91.1-1.1-1.0-0.60.90.8-0.7-0.6-0.10.0-0.00.5
Rest time, locomotor task time 20.40.51.4-0.01.2-1.11.11.1-1.10.6-0.60.4-0.4-0.60.10.10.4-0.4-0.4-0.5-0.1-0.10.50.6-0.5-1.11.1-0.8
Distance moved, locomotor task time 20.60.71.5-1.2-0.20.2-0.4-1.01.00.4-0.40.7-0.7-0.4-1.0-1.00.7-0.7-0.6-0.41.01.0-1.1-1.2-0.41.0-1.01.1
Vertical activity count, locomotor time 20.80.92.9-1.6-0.91.2-1.3-1.71.7-0.40.4-0.00.00.5-0.4-0.4-0.00.0-0.0-0.10.50.6-1.0-1.10.11.6-1.61.3
Light reinforcement 10.61.12.2-0.90.9-0.50.3-0.80.81.0-1.01.3-1.3-1.0-1.4-1.41.4-1.4-1.5-1.21.31.3-1.1-1.2-0.80.3-0.30.8
Light reinforcement 20.81.14.4-0.01.2-1.92.10.6-0.60.9-0.90.8-0.8-1.4-1.1-1.10.9-0.9-0.9-0.70.60.90.00.0-1.3-1.31.1-0.7
Bone: marrow area0.41.03.5-0.3-1.41.8-1.9-1.41.4-1.11.1-0.60.61.10.40.4-0.60.60.81.0-0.2-0.2-0.4-0.41.10.9-0.90.5
Bone: maximum diameter0.71.32.40.1-1.51.5-1.5-0.80.8-1.41.4-1.51.51.41.01.0-1.61.61.51.2-0.8-0.70.20.11.10.6-0.6-0.1
Bone: maximum force1.32.25.3-0.2-2.32.2-2.1-2.02.0-1.81.8-1.61.61.81.01.0-1.21.21.71.1-0.7-0.5-0.2-0.21.11.6-1.60.8
Bone: maximum moment1.52.56.3-0.3-2.52.4-2.4-2.12.1-2.02.0-1.71.72.01.11.1-1.31.31.81.1-0.8-0.6-0.2-0.21.31.7-1.70.8
Mean time between licks in bursts0.40.51.2-0.90.2-0.30.4-0.60.60.6-0.60.9-0.9-0.7-1.0-1.01.1-1.1-0.7-0.40.81.0-0.8-0.8-0.70.3-0.40.7
Mean num. licks in bursts2.93.56.50.9-2.01.4-1.30.4-0.4-2.22.2-2.32.32.22.02.0-2.12.12.42.6-2.2-2.11.81.82.4-0.70.8-1.4
Cd content in liver0.20.20.70.5-0.20.3-0.60.8-0.8-0.10.1-0.40.40.30.30.3-0.50.50.60.0-0.2-0.40.20.20.6-0.10.0-0.2
Co content in liver0.20.20.70.50.2-0.70.80.6-0.6-0.00.0-0.20.2-0.10.40.4-0.20.20.20.2-0.4-0.30.50.5-0.4-0.60.6-0.6
Cu content in liver0.40.51.0-0.6-0.90.9-0.8-0.70.7-1.01.0-0.70.71.00.90.9-0.80.80.80.6-0.5-0.40.20.10.20.8-0.80.3
Fe content in liver0.10.11.0-1.00.2-0.30.20.6-0.60.4-0.40.3-0.3-0.4-0.4-0.40.2-0.2-0.3-0.40.30.4-0.3-0.3-0.30.00.00.1
K content in liver0.10.10.3-0.30.5-0.30.3-0.20.20.3-0.30.4-0.4-0.3-0.2-0.20.6-0.6-0.4-0.30.20.2-0.1-0.1-0.2-0.10.10.1
Mg content in liver0.40.41.5-0.20.8-1.11.20.6-0.60.3-0.30.4-0.4-0.40.10.10.4-0.4-0.5-0.1-0.3-0.10.70.7-0.4-1.11.1-0.8
Mn content in liver1.01.13.91.21.4-1.51.42.0-2.00.8-0.80.1-0.1-0.9-0.2-0.20.1-0.1-0.3-0.0-0.2-0.31.01.00.2-1.71.8-1.4
Na content in liver0.60.61.9-1.2-0.31.1-1.3-1.21.2-0.20.20.1-0.10.3-0.2-0.20.1-0.1-0.1-0.30.50.5-1.0-1.00.01.4-1.41.2
Rb content in liver0.20.21.8-0.2-0.2-0.30.6-0.40.4-0.00.00.5-0.5-0.3-0.1-0.10.4-0.4-0.4-0.50.40.6-0.5-0.5-1.30.6-0.60.6
Se content in liver2.12.610.80.82.3-3.03.32.1-2.11.6-1.50.7-0.7-1.9-0.9-0.90.5-0.5-0.9-1.00.20.30.80.9-1.4-2.32.3-1.7
Sr content in liver0.60.52.0-0.41.1-1.11.01.4-1.40.8-0.80.3-0.3-0.7-0.5-0.50.3-0.3-0.3-0.50.1-0.00.30.30.0-1.11.1-0.7
Zn content in liver0.10.10.3-0.4-0.1-0.30.60.1-0.1-0.40.4-0.40.40.20.50.5-0.30.30.4-0.1-0.4-0.30.50.4-0.5-0.20.2-0.3
Bone: minimum diameter0.91.75.4-1.4-1.42.2-2.3-2.32.3-0.80.8-0.40.41.00.00.0-0.30.30.50.20.40.5-1.3-1.40.51.9-1.91.4
Time in familiar zone, hab. session 13.63.45.50.3-2.01.1-0.90.1-0.1-2.32.3-2.22.22.12.32.3-2.22.22.12.3-2.3-2.11.91.91.8-0.80.8-1.5
Time in novel zone, hab. session 14.84.77.9-1.02.5-1.71.60.1-0.12.7-2.72.6-2.6-2.7-2.7-2.72.8-2.8-2.5-2.42.62.4-2.0-1.9-2.10.4-0.41.4
Total zone transitions, hab. session 10.71.03.4-1.80.30.1-0.0-1.21.20.7-0.71.1-1.1-0.7-1.2-1.20.9-0.9-1.0-1.11.21.3-1.3-1.3-0.70.6-0.60.9
Total locomotion distance, hab. session 10.50.71.5-1.10.60.6-0.7-0.60.60.8-0.81.0-1.0-0.5-1.2-1.20.8-0.8-0.9-0.91.11.0-1.2-1.10.20.6-0.60.8
Locomotion velocity, hab. session 10.20.30.7-0.60.60.3-0.5-0.10.10.6-0.60.7-0.7-0.4-0.8-0.80.4-0.4-0.7-0.60.70.5-0.6-0.60.40.1-0.10.3
Time in familiar zone, hab. session 21.81.93.90.9-1.40.7-0.91.3-1.3-1.41.4-1.41.41.51.81.8-1.51.51.42.0-1.6-1.71.41.41.4-0.50.5-1.0
Time in novel zone, hab. session 20.80.81.9-0.51.2-0.70.8-0.60.61.0-1.01.0-1.0-1.1-1.3-1.30.9-0.9-0.9-1.41.01.0-0.7-0.7-0.80.0-0.00.4
Total zone transitions, hab. session 23.14.06.8-2.02.4-2.12.1-0.20.22.5-2.52.5-2.5-2.6-2.6-2.62.3-2.3-2.4-2.02.12.2-1.3-1.3-1.8-0.80.80.3
Total locomotion distance, hab. session 22.12.85.5-1.71.7-0.90.8-0.30.32.0-2.02.1-2.1-1.9-2.3-2.31.9-1.9-2.1-1.62.12.0-1.7-1.7-1.30.4-0.41.1
Locomotion velocity, hab. session 21.72.24.4-1.41.6-0.90.9-0.10.11.8-1.81.9-1.9-1.8-2.1-2.11.7-1.7-1.9-1.31.81.7-1.4-1.4-1.10.2-0.20.8
Novel to familiar place preference ratio0.20.20.6-0.4-0.30.2-0.4-0.40.40.1-0.10.3-0.30.0-0.2-0.20.5-0.5-0.3-0.10.30.3-0.5-0.5-0.30.7-0.70.8
Novelty place preference0.30.30.9-0.8-0.10.1-0.3-0.30.30.3-0.40.5-0.5-0.2-0.3-0.30.8-0.8-0.5-0.30.60.5-0.7-0.7-0.40.8-0.80.9
Time in novel zone, NPP test0.40.41.0-0.90.1-0.0-0.2-0.30.30.5-0.60.7-0.7-0.4-0.5-0.50.9-0.9-0.7-0.50.70.7-0.8-0.8-0.50.8-0.81.0
Total zone transitions, NPP test0.20.31.5-0.60.20.10.1-1.21.20.3-0.20.5-0.5-0.3-0.8-0.80.4-0.4-0.4-0.50.50.6-0.5-0.4-0.0-0.10.10.1
Total locomotion distance, NPP test0.40.52.7-0.2-0.71.6-1.6-1.11.1-0.50.5-0.20.20.8-0.2-0.2-0.30.30.40.50.0-0.1-0.4-0.41.40.6-0.60.4
Locomotion velocity, NPP test0.40.52.70.1-0.61.5-1.6-0.90.9-0.60.6-0.40.40.8-0.0-0.0-0.40.40.50.7-0.2-0.3-0.2-0.21.50.4-0.40.2
Intraocular pressure0.40.61.30.80.2-0.10.10.2-0.20.7-0.70.9-0.9-0.7-0.9-0.91.1-1.1-0.7-0.21.00.8-0.9-0.9-0.90.6-0.51.0
Delta distance traveled before/after self-admin1.51.65.2-0.2-2.02.3-2.1-1.91.9-1.41.3-0.80.81.40.60.6-0.80.80.80.8-0.1-0.1-0.7-0.70.91.7-1.71.1
Delta ambulatory time before/after self-admin1.61.86.0-0.3-2.02.5-2.4-2.12.1-1.41.3-0.70.71.40.50.5-0.70.70.70.8-0.1-0.1-0.9-0.90.91.9-1.91.3
Parametrial fat weight3.97.517.64.2-1.2-0.10.32.2-2.2-2.12.2-2.82.81.92.82.8-2.92.92.92.8-3.4-3.33.63.62.7-2.72.6-3.4
Pavlov. Cond. lever latency1.21.53.40.7-1.60.8-0.80.5-0.5-1.61.6-1.31.31.51.91.9-1.41.41.51.6-1.4-1.41.01.00.70.2-0.2-0.4
Pavlov. Cond. magazine entry latency2.02.65.4-1.02.3-1.10.9-0.40.42.1-2.12.1-2.1-2.0-2.3-2.31.9-1.9-2.2-1.31.71.6-1.1-1.0-0.2-0.80.80.2
Pavlov. Cond. change in total contacts4.34.67.7-2.02.1-0.90.8-1.71.72.4-2.42.6-2.6-2.2-2.8-2.82.8-2.8-2.7-2.52.52.5-2.1-2.1-1.50.6-0.61.6
Pavlov. Cond. index score2.22.85.9-1.02.4-1.31.1-0.50.52.2-2.22.1-2.1-2.1-2.4-2.42.0-2.0-2.2-1.61.81.7-1.2-1.1-0.6-0.70.70.2
Pavlov. Cond. latency score2.02.55.4-1.12.1-1.10.9-0.70.72.1-2.11.9-1.9-1.9-2.3-2.31.9-1.9-2.0-1.61.81.7-1.3-1.2-0.7-0.40.40.4
Pavlov. Cond. lever contacts0.91.12.7-0.51.2-0.50.4-0.80.81.3-1.31.2-1.2-1.2-1.6-1.61.2-1.2-1.4-1.21.31.2-1.0-1.0-0.5-0.00.00.4
Pavlov. Cond. magazine entry number2.43.06.40.9-2.41.2-1.00.7-0.7-2.22.2-2.32.32.12.52.5-2.22.22.31.5-1.9-1.81.31.20.50.6-0.6-0.4
Pavlov. Cond. intertrial magazine entries0.20.21.7-1.30.1-0.70.70.2-0.2-0.00.0-0.20.20.10.50.5-0.30.3-0.1-0.2-0.4-0.20.50.5-0.5-0.20.2-0.3
Pavlov. Cond. lever-magazine prob. diff.2.83.57.2-1.12.6-1.51.3-0.60.62.5-2.42.3-2.3-2.3-2.7-2.72.2-2.2-2.4-1.82.11.9-1.4-1.3-0.8-0.70.70.3
Pavlov. Cond. response bias1.11.43.2-0.41.8-0.90.7-0.40.41.5-1.51.6-1.6-1.4-1.7-1.71.4-1.4-1.6-0.91.11.0-0.6-0.50.1-0.90.9-0.2
Pavlov. Cond. lever latency1.72.36.60.92.1-2.62.52.6-2.61.7-1.70.8-0.8-1.9-1.0-1.01.0-1.0-0.8-1.10.50.40.40.5-1.2-1.71.7-1.0
Pavlov. Cond. magazine entry latency0.50.52.0-1.0-0.91.4-1.4-0.80.8-0.80.8-0.30.31.00.50.5-0.50.50.30.5-0.3-0.2-0.2-0.30.70.8-0.80.5
Pavlov. Cond. change in total contacts2.63.611.4-1.1-2.73.2-3.4-3.03.0-1.91.8-0.90.92.10.90.9-1.01.00.91.2-0.1-0.1-1.1-1.21.12.8-2.81.8
Pavlov. Cond. index score1.41.86.0-1.2-1.82.5-2.5-2.12.1-1.41.4-0.60.61.60.70.7-0.80.80.61.0-0.3-0.2-0.6-0.61.21.7-1.61.0
Pavlov. Cond. latency score1.31.65.2-1.2-1.62.3-2.3-2.02.0-1.31.3-0.50.51.50.70.7-0.80.80.50.8-0.2-0.2-0.6-0.61.01.6-1.61.0
Pavlov. Cond. lever contacts1.62.26.7-1.1-2.02.5-2.5-2.62.6-1.61.5-0.60.61.70.80.8-0.80.80.60.9-0.3-0.2-0.6-0.71.01.9-1.91.2
Pavlov. Cond. magazine entry number1.31.55.11.31.8-2.32.31.6-1.61.4-1.40.8-0.8-1.6-0.7-0.70.9-0.9-0.8-1.10.40.30.40.4-1.3-1.31.3-0.7
Pavlov. Cond. intertrial magazine entries0.30.41.51.20.5-0.90.91.2-1.20.3-0.3-0.10.1-0.50.20.2-0.00.00.1-0.3-0.1-0.20.50.5-0.6-0.70.7-0.6
Pavlov. Cond. lever-magazine prob. diff.1.41.86.0-1.1-1.82.4-2.4-1.91.9-1.51.5-0.80.81.70.80.8-0.90.90.71.1-0.4-0.4-0.4-0.41.31.4-1.40.8
Pavlov. Cond. response bias1.82.47.5-1.7-2.12.7-2.7-2.72.7-1.51.5-0.50.51.70.60.6-0.60.60.40.8-0.10.1-0.9-1.01.02.1-2.11.5
Time in closed arm before self-admin2.42.75.3-1.12.1-1.61.70.2-0.22.1-2.21.9-1.9-2.0-1.8-1.81.9-1.9-1.9-2.31.61.6-1.1-1.1-1.9-0.00.00.8
Time in closed arm after self-admin0.10.10.4-0.3-0.30.20.1-0.60.6-0.10.1-0.00.0-0.2-0.1-0.1-0.00.00.1-0.40.40.5-0.4-0.4-0.60.5-0.50.4
Time in open arm before self-admin2.42.64.80.6-2.02.0-2.2-0.40.4-2.12.1-1.61.62.11.91.9-1.61.61.72.2-1.6-1.71.01.02.10.3-0.3-0.4
Time in open arm after self-admin0.30.31.90.7-0.40.9-1.2-0.00.0-0.40.4-0.30.30.70.40.4-0.30.30.40.8-0.4-0.60.20.21.40.1-0.1-0.1
Bone: periosteal estimation0.81.64.3-0.1-1.92.1-2.1-1.51.5-1.61.6-1.41.41.60.80.8-1.31.31.51.4-0.6-0.5-0.1-0.21.50.9-0.90.2
Bone: periosteal perimeter0.50.81.90.1-1.01.2-1.4-0.60.6-0.90.9-1.31.31.00.50.5-1.21.21.31.1-0.5-0.50.10.11.20.2-0.2-0.3
Bone: post-yield work1.21.75.1-1.6-1.21.4-1.5-2.32.3-0.40.30.5-0.50.4-0.5-0.50.6-0.6-0.4-0.30.91.0-1.6-1.6-0.32.2-2.22.0
Progressive ratio test 1 active lever presses2.42.56.2-2.50.30.7-0.8-1.91.90.9-0.91.7-1.7-0.5-1.5-1.51.7-1.7-1.6-1.71.51.5-2.1-2.1-1.11.7-1.72.1
Progressive ratio test 1 breakpoint1.51.64.6-2.1-0.00.9-1.0-1.71.70.5-0.51.2-1.2-0.1-1.0-1.01.2-1.2-1.2-1.31.11.1-1.7-1.7-0.71.6-1.61.8
Progressive ratio test 1 inactive lever presses2.73.08.3-2.90.10.4-0.3-2.02.00.8-0.91.8-1.8-0.9-1.6-1.61.8-1.8-1.5-1.91.92.1-2.1-2.1-1.61.8-1.92.2
Progressive ratio test 2 active lever presses2.32.57.9-2.80.90.2-0.3-1.51.51.3-1.31.8-1.8-0.9-1.7-1.71.8-1.8-1.7-1.81.71.7-2.0-2.0-1.21.2-1.21.7
Progressive ratio test 2 breakpoint2.12.47.5-2.71.00.1-0.2-1.31.31.3-1.31.8-1.8-1.0-1.7-1.71.8-1.8-1.7-1.81.61.6-1.8-1.8-1.11.0-1.01.5
Progressive ratio test 2 inactive lever presses4.04.78.5-2.80.20.5-0.3-2.72.71.1-1.12.2-2.2-1.1-2.1-2.12.2-2.2-1.9-2.12.52.6-2.9-2.9-2.52.4-2.42.8
Incentive Sensitization - Responses0.80.85.3-2.30.60.0-0.0-0.70.70.7-0.70.9-0.9-0.5-1.0-1.00.9-0.9-0.8-0.90.90.9-1.1-1.1-0.60.5-0.50.8
Incentive Sensitization - Breakpoint0.60.64.5-2.10.40.1-0.1-0.60.60.6-0.50.8-0.8-0.4-0.9-0.90.7-0.7-0.6-0.70.80.8-0.9-0.9-0.50.5-0.50.7
Sum of active levers in priming session hrs 5-60.30.20.8-0.9-0.50.4-0.3-0.00.0-0.70.7-0.60.60.60.60.6-0.60.60.60.5-0.5-0.40.20.20.00.2-0.2-0.1
Progressive ratio0.30.30.70.30.6-0.50.2-0.10.10.8-0.70.7-0.7-0.6-0.8-0.80.8-0.8-0.8-0.90.60.5-0.5-0.5-0.1-0.20.20.2
Food seeking constrained by brief footshock0.50.62.8-0.6-0.91.4-1.7-0.90.9-0.80.7-0.60.60.90.30.3-0.50.50.20.3-0.1-0.2-0.3-0.41.00.9-0.80.6
Seeking ratio, punishment vs. effort0.30.43.0-1.7-0.60.9-0.8-0.70.7-0.60.5-0.20.20.50.30.3-0.20.20.10.10.10.2-0.4-0.40.10.9-0.80.7
Retroperitoneal fat weight0.51.74.21.30.8-1.81.81.9-1.90.2-0.1-0.50.5-0.20.80.8-0.60.60.70.5-1.3-1.32.02.00.6-2.01.9-1.9
Reaction time number correct0.10.20.8-0.9-0.40.1-0.1-0.40.4-0.70.7-0.30.30.50.50.5-0.40.40.40.6-0.5-0.30.40.40.3-0.00.1-0.2
Reaction time mean minus median0.30.40.90.6-0.60.9-0.8-0.10.1-0.60.6-0.90.90.80.80.8-0.60.60.90.6-0.6-0.70.40.40.70.6-0.50.2
Reaction time mean minus median AUC0.91.22.01.0-1.11.3-1.2-0.20.2-1.31.3-1.41.41.41.41.4-1.21.21.41.2-1.1-1.20.70.71.20.6-0.6-0.0
Reaction time num false alarms0.30.31.10.40.9-1.00.90.7-0.70.7-0.70.3-0.3-0.9-0.5-0.50.2-0.2-0.4-0.70.50.4-0.2-0.2-0.9-0.30.3-0.2
Reaction time num false alarms AUC0.40.61.60.41.2-1.31.11.1-1.11.0-1.00.5-0.5-1.1-0.6-0.60.4-0.4-0.6-0.70.60.4-0.2-0.2-0.9-0.60.5-0.3
Reaction time trials correct on left0.10.20.8-0.9-0.40.1-0.1-0.40.4-0.70.7-0.30.30.50.50.5-0.40.40.40.6-0.5-0.30.40.40.3-0.00.1-0.2
Reaction time trials on left0.10.20.7-0.8-0.40.1-0.1-0.30.3-0.70.7-0.40.40.50.50.5-0.40.40.40.6-0.5-0.30.50.50.3-0.10.1-0.2
Reaction time mean0.10.20.60.7-0.10.7-0.7-0.50.5-0.0-0.00.0-0.00.1-0.2-0.20.1-0.10.00.10.30.2-0.5-0.50.40.6-0.60.5
Reaction time mean AUC0.10.10.60.80.10.5-0.4-0.20.20.1-0.10.1-0.10.0-0.2-0.20.2-0.2-0.00.10.20.1-0.4-0.30.50.3-0.30.3
Median of all reaction times0.20.20.60.70.20.4-0.4-0.50.50.4-0.40.5-0.5-0.3-0.6-0.60.4-0.4-0.5-0.20.60.5-0.8-0.70.20.4-0.40.5
Reaction time omissions0.20.22.91.7-0.1-0.10.10.6-0.6-0.00.1-0.10.10.00.10.1-0.10.10.20.6-0.3-0.40.40.50.6-0.60.6-0.5
Reaction time false alarm rate0.50.71.40.81.1-1.10.91.0-1.01.2-1.20.6-0.6-1.1-0.8-0.80.6-0.6-0.7-0.90.80.6-0.5-0.5-1.0-0.30.2-0.0
Reaction time premature initiation rate1.01.32.1-1.41.3-0.30.2-0.60.61.4-1.41.3-1.3-1.0-1.3-1.31.1-1.1-1.5-1.41.31.2-1.3-1.3-1.10.7-0.81.0
Reaction time premature initiations0.60.93.0-1.71.0-0.20.2-0.80.81.0-1.01.0-1.0-0.7-0.9-0.90.7-0.7-1.1-1.11.01.0-1.0-1.0-0.90.7-0.70.8
Std. dev. reaction times0.30.41.50.5-0.61.2-1.1-0.60.6-0.50.5-0.40.40.70.30.3-0.20.20.40.50.0-0.1-0.4-0.40.61.2-1.20.9
Reaction time trials completed0.10.20.7-0.8-0.40.1-0.1-0.30.3-0.70.7-0.40.40.50.50.5-0.40.40.40.6-0.5-0.30.50.50.3-0.10.1-0.2
Reaction time trials AUC0.30.40.8-0.5-0.50.1-0.00.0-0.0-0.80.9-0.60.60.60.80.8-0.70.70.70.9-0.8-0.60.80.80.6-0.40.4-0.6
Run reversals in cocaine runway, females0.60.61.6-0.9-1.11.1-1.1-1.01.0-0.80.8-0.40.40.70.40.4-0.40.40.40.40.00.1-0.5-0.50.01.3-1.10.9
Run reversals in cocaine runway, males2.92.86.11.5-0.3-0.50.52.1-2.1-0.90.9-1.41.40.81.51.5-1.41.41.41.2-2.0-2.02.32.31.9-2.32.2-2.5
Latency to leave start box in cocaine runway0.40.41.8-0.2-0.50.8-0.6-1.11.1-0.50.5-0.20.20.50.30.3-0.20.20.2-0.50.20.3-0.6-0.7-0.61.3-1.31.0
Latency to leave start box in cocaine runway, F0.40.41.4-1.2-0.40.4-0.2-1.01.0-0.30.30.2-0.20.1-0.2-0.20.2-0.2-0.1-0.70.40.6-0.8-0.8-0.91.0-1.10.9
Latency to leave start box in cocaine runway, M0.30.32.41.6-0.10.4-0.40.1-0.1-0.20.2-0.70.70.40.60.6-0.70.70.50.2-0.2-0.40.10.10.30.4-0.10.0
Std. dev. time between licks in bursts2.93.55.5-1.51.2-0.50.3-1.41.41.8-1.82.2-2.2-1.7-2.3-2.32.3-2.3-2.0-2.02.42.3-2.3-2.3-1.71.2-1.21.8
Total sessions with >9 infusions1.21.32.3-1.11.5-1.10.90.3-0.31.5-1.51.4-1.4-1.4-1.5-1.51.4-1.4-1.3-1.21.11.1-0.8-0.7-0.6-0.60.60.1
Short access day 1 total inactive lever presses2.93.210.4-3.20.60.20.0-2.12.10.9-0.91.6-1.6-0.9-1.6-1.61.5-1.5-1.6-2.11.92.1-2.2-2.3-2.32.0-2.02.2
Short access day 10 total inactive lever presses0.50.61.8-1.0-1.11.0-0.8-1.21.2-0.90.9-0.30.30.70.50.5-0.40.40.50.20.00.2-0.4-0.4-0.31.3-1.30.9
Short access day 1 total infusions0.90.92.8-1.70.6-0.20.2-0.50.50.7-0.71.1-1.1-0.9-1.5-1.51.2-1.2-0.8-0.91.21.3-1.2-1.1-0.60.2-0.20.6
Short access day 10 total infusions0.60.71.4-0.50.8-0.50.4-0.20.21.1-1.11.0-1.0-1.0-1.2-1.21.0-1.0-0.8-1.11.01.0-0.9-0.9-0.8-0.0-0.00.4
Short access total infusions0.91.02.2-1.01.1-0.90.70.2-0.21.3-1.31.3-1.3-1.2-1.5-1.51.3-1.3-1.0-1.11.01.0-0.8-0.8-0.6-0.50.50.1
Short access day 1 locomotion0.10.20.4-0.10.6-0.40.4-0.30.30.4-0.40.4-0.4-0.5-0.4-0.40.4-0.4-0.2-0.60.50.5-0.3-0.3-0.5-0.10.10.1
Short access day 10 total locomotion1.71.93.1-1.50.60.4-0.5-1.61.61.0-1.11.4-1.4-0.8-1.4-1.41.4-1.4-1.3-1.41.71.6-1.8-1.8-0.91.4-1.41.7
Short access total locomotion1.31.32.5-0.71.5-1.11.1-0.10.11.5-1.51.4-1.4-1.5-1.4-1.41.4-1.4-1.1-1.61.31.2-0.9-0.8-1.1-0.30.30.4
One hour access (0.3 mA shock)3.84.510.6-3.30.70.8-1.1-2.22.21.4-1.42.4-2.4-1.0-2.3-2.32.5-2.5-2.2-1.92.42.3-2.8-2.8-1.11.9-1.92.5
Compulsive drug intake0.10.12.0-1.4-0.10.0-0.2-0.10.1-0.10.10.3-0.30.1-0.1-0.10.4-0.4-0.3-0.3-0.00.0-0.1-0.10.2-0.00.00.1
One hour access (shock baseline)2.32.64.5-1.71.10.1-0.1-1.31.31.5-1.51.9-1.9-1.3-2.0-2.02.0-2.0-1.7-1.62.02.0-2.1-2.1-1.31.1-1.11.7
Social response proportion1.01.12.7-0.8-1.61.2-1.0-1.11.1-1.31.3-1.31.31.20.90.9-1.41.41.41.0-0.7-0.50.10.10.31.0-1.00.3
Social responses0.30.31.4-1.2-0.50.3-0.1-0.20.2-0.60.6-0.60.60.60.60.6-1.11.10.80.3-0.6-0.40.30.30.0-0.10.1-0.5
Social time1.21.64.9-1.9-1.72.0-1.9-2.22.2-1.11.1-0.20.21.10.20.2-0.60.60.30.80.30.5-1.1-1.10.31.8-1.81.3
Soleus weight0.10.40.90.4-0.1-0.40.40.7-0.7-0.40.5-0.60.60.30.80.8-0.60.60.70.5-0.7-0.70.91.00.2-0.80.8-0.9
Bone: stiffness0.91.44.0-0.2-2.01.6-1.4-1.71.7-1.51.5-1.41.41.30.70.7-0.90.91.51.0-0.5-0.3-0.2-0.20.51.4-1.40.7
Tibialis anterior weight1.34.412.53.5-1.60.6-0.31.3-1.3-2.12.1-2.42.41.72.32.3-2.42.42.52.2-2.4-2.42.42.41.7-1.51.4-2.2
Time to tail flick, vehicle, before self-admin0.60.61.2-0.21.0-1.01.10.3-0.30.9-0.91.1-1.1-0.9-0.9-0.91.1-1.1-1.1-0.70.60.7-0.3-0.4-0.8-0.20.20.2
Time to tail flick, vehicle, after self-admin0.30.41.21.10.9-0.60.50.8-0.81.0-1.00.3-0.3-0.8-0.6-0.60.3-0.3-0.3-0.50.50.3-0.3-0.10.0-0.60.6-0.4
Time to tail flick, test, before self-admin3.63.57.3-2.70.70.00.1-1.81.81.2-1.22.0-2.0-1.2-1.9-1.92.0-2.0-2.0-1.92.12.2-2.5-2.4-1.71.9-1.92.4
Time to tail flick, test, after self-admin0.30.30.6-0.80.30.00.0-0.30.30.4-0.40.7-0.7-0.3-0.7-0.70.7-0.7-0.60.10.50.5-0.7-0.7-0.30.5-0.50.7
Delta time to tail flick, vehicle, before/after SA0.10.10.50.70.10.4-0.60.0-0.00.3-0.4-0.00.0-0.1-0.1-0.1-0.00.00.0-0.20.30.1-0.4-0.20.60.1-0.10.1
Delta time to tail flick, test, before/after SA1.91.73.81.70.3-0.70.62.0-2.0-0.20.2-0.90.90.30.90.9-0.90.90.91.3-1.3-1.41.81.71.2-1.91.9-1.9
Tibia length1.74.713.0-0.7-3.63.3-3.2-2.82.8-2.82.8-2.02.02.71.51.5-1.91.91.72.1-1.1-0.9-0.1-0.12.02.1-2.21.0
Ambulatory time before self-admin0.10.10.4-0.50.6-0.20.20.3-0.30.3-0.30.2-0.2-0.20.10.10.2-0.2-0.2-0.30.0-0.10.30.2-0.2-0.10.00.0
Ambulatory time after self-admin2.22.47.8-1.6-1.92.8-2.6-2.52.5-1.51.4-0.80.81.60.70.7-0.80.80.70.5-0.0-0.1-0.8-0.90.72.5-2.51.7
Bone: tissue strength1.51.45.5-1.3-1.81.8-1.8-1.51.5-1.01.0-0.40.41.10.20.2-0.30.30.5-0.10.20.3-1.0-1.10.02.3-2.31.8
Total heroin consumption0.30.42.1-1.5-0.10.4-0.4-0.90.90.0-0.00.3-0.30.0-0.2-0.20.3-0.3-0.3-0.40.50.5-0.7-0.7-0.81.0-1.00.9
Bone: trabecular number0.91.43.90.5-1.71.8-1.7-2.02.0-1.51.5-0.90.91.50.90.9-0.80.80.91.0-0.7-0.60.10.11.01.2-1.20.7
Bone: trabecular spacing0.40.53.10.10.3-0.2-0.11.8-1.80.2-0.2-0.30.30.00.40.4-0.30.30.20.2-0.4-0.60.60.60.7-1.00.9-0.9
Bone: trabecular thickness0.20.20.60.1-0.50.5-0.3-0.80.8-0.70.7-0.40.40.60.50.5-0.60.60.50.3-0.5-0.30.20.20.20.2-0.1-0.1
Bone: trabecular tissue density1.92.79.80.51.0-1.51.43.1-3.10.2-0.2-1.01.0-0.10.70.7-0.90.90.80.8-1.5-1.52.12.11.0-2.82.8-2.6
Water consumed over 24 hours0.30.41.0-0.5-1.01.0-0.8-0.70.7-0.90.9-0.40.40.80.40.4-0.80.80.40.7-0.3-0.2-0.1-0.00.50.5-0.40.1
Number of responses in last shaping day3.43.67.9-2.80.9-0.20.1-1.41.41.6-1.62.2-2.2-1.5-2.4-2.42.2-2.2-1.9-2.12.22.3-2.3-2.3-1.61.3-1.31.9