Hub : Genes

Urgcp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr14_84819217_84852612 0.03 0.02 3.1e-03 0.03 0.04 0.02 0.04 8.7e-04 8.0e-04 1.4e-02 7.8e-04
2 LHb alternative TSS XM_006251315.5 0.18 0.13 4.5e-03 0.08 0.08 0.05 0.03 5.5e-03 5.6e-03 2.7e-02 7.2e-02
3 NAcc mRNA stability Urgcp 0.04 0.03 1.4e-04 0.03 0.01 0.02 0.02 9.5e-06 9.9e-03 3.8e-04 1.2e-04
4 Brain alternative TSS XM_063273225.1 0.05 0.04 9.3e-03 0.01 0.02 0.01 0.01 4.2e-02 9.8e-03 3.5e-02 2.8e-02
5 RMTg isoform ratio NM_001077660.2 0.56 0.19 1.8e-03 0.11 0.05 0.1 0.1 8.4e-04 1.6e-02 1.4e-03 1.3e-03
6 Brain mRNA stability Urgcp 0.16 0.08 1.6e-06 0.06 0.07 0.06 0.07 1.8e-06 3.5e-07 2.4e-06 2.7e-07
7 BLA mRNA stability Urgcp 0.25 0.15 4.3e-04 0.04 0.06 0.05 0.05 2.4e-03 6.6e-04 1.5e-03 7.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.00.00.10.2-0.1-0.10.3-0.0-0.0-0.2
Area under the delay curve1.52.24.8-2.2-1.91.9-0.4-1.3-1.3-0.2
BMI with tail0.10.31.1-0.7-1.10.7-0.2-0.2-0.20.1
BMI without tail0.20.82.8-1.3-1.70.8-0.2-0.5-0.5-0.1
Body weight0.83.48.2-2.9-2.82.3-1.1-0.7-0.70.4
Weight adjusted by age0.10.30.9-0.9-0.90.5-0.2-0.3-0.3-0.1
Bone surface0.10.30.6-0.2-0.00.3-0.70.50.50.8
Bone volume0.10.20.4-0.2-0.20.3-0.60.40.40.6
Breakpoint value in progressive ratio session0.30.61.5-1.1-1.21.0-0.5-0.1-0.10.3
Number of licking bursts0.61.83.9-2.0-1.61.9-1.30.30.30.9
Context. condit. distance diff. score1.92.35.62.42.1-2.20.80.60.6-0.2
Locomotion velocity, session 10.20.30.40.20.6-0.5-0.40.60.60.5
Locomotion distance, session 11.62.13.60.2-0.60.41.9-1.8-1.8-1.9
Locomotion velocity, session 21.51.72.80.61.1-1.0-1.31.71.71.6
Locomotion distance, session 20.60.81.61.20.6-0.71.3-0.7-0.7-0.9
Locomotion velocity, session 30.80.92.61.61.0-0.81.2-0.3-0.3-0.8
Locomotion distance, session 30.30.31.2-0.2-0.61.1-0.50.20.20.7
Stereotopy head waving bouts, day 30.30.40.80.80.3-0.60.9-0.3-0.3-0.7
Stereotopy head waving duration, day 31.01.22.51.51.3-1.61.1-0.0-0.0-0.9
Locomotion velocity, session 70.10.10.4-0.2-0.20.1-0.60.30.30.6
Locomotion distance, session 70.10.20.40.60.4-0.6-0.10.30.30.4
Stereotopy head waving bouts, day 70.20.30.60.50.7-0.8-0.10.50.50.2
Stereotopy head waving duration, day 70.00.10.10.20.4-0.30.2-0.1-0.1-0.3
Locomotion velocity, session 81.82.24.41.92.1-2.1-0.21.11.10.8
Locomotion distance, session 83.34.912.03.52.8-3.11.90.10.1-1.0
Degree of sensitization distance1.71.85.81.61.9-2.40.60.60.6-0.2
Degree of sensitization stereotypy0.10.10.1-0.00.3-0.3-0.30.30.30.2
Conditioned locomotion1.82.13.70.4-0.40.51.9-1.8-1.8-1.9
Cocaine response after cond. corrected0.60.92.4-1.6-1.11.4-0.90.20.20.5
Cocaine response after cond. not corrected0.91.33.2-1.8-1.51.7-0.7-0.0-0.00.2
Cocaine response before conditioning0.20.30.80.3-0.10.00.9-0.5-0.5-0.8
Saline control response0.30.40.80.90.8-0.80.00.60.60.3
Bone: connectivity density0.10.10.30.60.3-0.50.30.10.1-0.1
Bone: cortical apparent density0.20.20.6-0.7-0.30.2-0.70.30.30.6
Bone: cortical area1.11.84.1-2.0-1.82.0-0.7-0.6-0.60.3
Bone: cortical porosity0.10.10.2-0.4-0.50.4-0.1-0.2-0.20.1
Bone: cortical porosity0.20.20.30.1-0.20.10.5-0.6-0.6-0.5
Bone: cortical thickness1.21.94.8-1.9-1.92.2-0.4-0.8-0.8-0.0
Bone: cortical thickness0.81.02.10.3-0.40.31.4-1.2-1.2-1.3
Bone: cortical tissue density0.20.30.7-0.7-0.30.2-0.90.40.40.7
Condit. Reinf. active minus inactive responses0.91.02.1-0.6-0.30.2-1.51.01.01.4
Condit. Reinf. active-inactive response ratio2.32.53.90.51.1-1.5-1.62.02.01.8
Condit. Reinf. active responses0.30.40.9-0.4-0.30.6-0.90.40.40.9
Condit. Reinf. inactive responses0.70.93.0-0.5-0.91.70.3-0.9-0.9-0.4
Incentive salience index mean0.60.81.3-1.1-1.01.0-1.10.30.31.0
Condit. Reinf. lever presses0.91.32.1-0.9-1.41.50.5-1.3-1.3-0.7
Condit. Reinf. active minus inactive responses0.30.41.21.10.8-0.70.6-0.2-0.2-0.4
Condit. Reinf. active-inactive response ratio0.00.10.10.2-0.0-0.10.3-0.3-0.3-0.3
Condit. Reinf. active responses0.40.51.31.10.8-0.90.7-0.2-0.2-0.6
Condit. Reinf. inactive responses0.40.61.51.11.1-1.20.40.30.3-0.1
Condit. Reinf. lever presses0.30.41.01.00.9-0.60.50.00.0-0.4
Condit. Reinf. lever reinforcers received0.30.41.01.00.6-0.80.6-0.2-0.2-0.5
Conditioned reinforcement - actives0.00.00.1-0.4-0.2-0.1-0.2-0.2-0.20.1
Conditioned reinforcement - inactives0.10.40.8-0.9-0.80.8-0.60.0-0.00.5
Conditioned locomotion0.20.30.9-0.7-0.90.1-0.3-0.4-0.40.1
Patch foraging indifference point 0 sec1.13.25.9-1.2-0.70.6-2.42.12.12.3
Patch foraging indifference point AUC0.10.30.6-0.00.1-0.5-0.60.80.80.6
Delay disc. indifference point, 0s delay0.70.72.0-1.4-1.01.3-0.4-0.4-0.4-0.0
Delay disc. indifference point, 16s delay0.71.02.5-1.6-1.51.0-0.8-0.4-0.40.3
Delay disc. indifference point, 2s delay2.32.65.3-1.9-1.82.30.2-1.6-1.6-0.8
Delay disc. indifference point, 24s delay0.50.82.0-1.4-1.21.1-0.6-0.5-0.60.2
Delay disc. indifference point, 4s delay2.42.54.8-2.2-2.02.0-0.2-1.5-1.5-0.5
Delay disc. indifference point, 8s delay0.71.11.8-1.2-1.11.10.2-1.4-1.4-0.6
Indifference point function ln k0.20.71.3-0.2-0.61.20.7-1.0-1.1-0.8
Indifference point function log k0.20.71.3-0.2-0.61.20.7-1.0-1.1-0.8
Patch foraging total patch changes 0 sec1.33.86.7-1.2-0.60.5-2.62.42.42.5
Patch foraging total patch changes 12 sec1.62.23.7-0.7-0.2-0.2-1.91.91.91.9
Patch foraging total patch changes 18 sec1.73.96.7-0.60.1-0.5-2.62.62.62.6
Patch foraging total patch changes 24 sec1.13.76.11.81.8-2.5-0.82.32.31.4
Patch foraging total patch changes 6 sec2.03.46.0-1.3-1.00.7-2.52.12.12.4
Patch foraging time to switch 0 sec0.20.71.20.60.5-0.61.1-0.9-0.9-1.1
Patch foraging water rate 0 sec0.72.64.6-1.3-0.91.1-2.21.71.72.1
Patch foraging water rate 12 sec0.00.20.3-0.1-0.10.5-0.50.40.40.6
Patch foraging water rate 18 sec1.32.95.4-0.4-1.31.11.6-2.3-2.3-1.9
Patch foraging water rate 24 sec0.00.10.20.1-0.5-0.3-0.1-0.2-0.20.1
Patch foraging water rate 6 sec0.50.71.5-0.7-1.01.20.2-0.8-0.8-0.4
Seeking ratio, delayed vs. immediate footshock1.31.94.00.0-0.6-0.31.3-2.0-2.0-1.7
Distance traveled before self-admin0.10.20.50.10.30.0-0.50.70.70.5
Distance traveled after self-admin0.10.20.3-0.2-0.40.10.3-0.6-0.6-0.4
Extensor digitorum longus weight1.45.713.0-3.6-3.03.0-2.50.20.21.7
Bone: elastic displacement0.20.20.60.50.5-0.80.50.10.1-0.4
Bone: elastic work0.40.50.9-0.8-1.00.50.4-0.7-0.7-0.6
Bone: endosteal estimation0.00.00.1-0.00.2-0.3-0.20.20.20.1
Bone: endosteal perimeter0.20.61.2-1.1-0.90.8-0.0-0.8-0.8-0.4
Epididymis fat weight0.10.71.7-1.2-1.21.3-0.6-0.1-0.10.3
Delta time in closed arm before/after self-admin6.15.79.62.62.1-2.03.1-2.0-2.0-2.7
Delta time in open arm before/after self-admin3.64.37.0-2.4-1.61.6-2.61.91.92.2
Diff in mean of infusions in LGA sessions0.30.51.1-0.0-0.30.10.7-1.1-1.1-0.8
Delay discount exponential model param1.52.14.52.11.9-1.80.41.21.20.2
Extinction: sum of active levers before priming0.10.10.2-0.2-0.2-0.5-0.30.20.20.3
Active lever presses in extinction session 61.11.12.4-0.3-0.40.61.1-1.6-1.5-1.2
Bone: final force0.20.30.6-0.3-0.20.1-0.80.50.50.8
Bone: final moment0.20.30.7-0.5-0.40.3-0.80.50.50.8
Food consumed during 24 hour testing period0.81.73.9-1.1-0.30.7-2.01.21.21.8
Glucose13.721.747.3-3.1-0.40.5-6.95.15.16.5
Heart weight1.32.03.70.30.7-0.5-1.61.91.91.9
Delay discount hyperbolic model param1.92.44.82.22.0-2.00.31.41.40.3
Intermittent access intake day 1-15 change0.31.72.9-0.6-0.5-0.0-1.61.71.71.7
Intermittent access intake escalation0.31.42.5-0.5-0.50.1-1.51.51.51.6
Intermittent access intake escalation 20.81.42.9-0.1-0.1-0.0-1.31.71.71.5
Intermitt. access day 1 inactive lever presses0.00.40.70.20.1-0.70.7-0.8-0.8-0.7
Intermitt. access day 15 inactive lever presses0.31.93.0-1.5-1.21.0-1.71.31.31.5
Intermitt. access escalation Index0.61.94.10.30.1-0.8-1.32.02.01.6
Intermittent access day 1 total infusions0.30.91.8-0.8-0.70.70.5-1.3-1.3-0.8
Intermittent access day 15 total infusions0.51.32.1-1.4-1.31.0-1.40.60.61.2
Intermittent access terminal intake (last 3 days)0.61.11.8-0.8-0.70.7-1.31.21.21.3
Intermittent access total infusions0.50.61.6-1.3-1.11.0-0.70.00.00.5
Intermittent access day 1 locomotion1.22.35.70.0-0.3-0.31.4-2.4-2.4-1.6
Intermittent access day 15 total locomotion0.20.61.5-1.0-1.20.6-0.3-0.8-0.8-0.1
Intermittent access total locomotion0.70.91.8-1.2-1.30.8-0.2-1.0-1.0-0.1
Intermittent access standard deviation0.10.51.01.01.0-0.90.10.60.60.2
Left kidney weight0.21.52.6-1.0-1.10.60.9-1.6-1.6-1.3
Right kidney weight0.31.83.0-0.6-1.21.01.3-1.7-1.7-1.5
Cocaine induced anxiety0.82.14.3-2.1-1.61.5-1.70.70.71.4
Post-drug Anxiety1.31.53.2-1.8-1.71.2-1.30.30.31.1
Baseline Anxiety0.40.71.40.5-0.1-0.50.8-1.2-1.2-0.9
Tail length0.94.811.5-3.4-3.32.8-1.5-0.5-0.50.8
Length with tail1.04.511.0-3.3-2.92.8-1.6-0.4-0.40.9
Length without tail0.10.51.4-1.1-0.91.2-0.4-0.2-0.20.2
Times rat made contact with spout4.34.97.91.01.9-1.5-2.22.82.82.7
Lifetime Intake0.40.51.4-1.2-1.01.0-0.5-0.2-0.20.2
Liver weight, left0.61.11.90.3-0.10.01.3-1.4-1.4-1.4
Liver weight, right1.32.24.30.80.3-0.12.1-1.8-1.8-2.0
Locomotor activity1.01.63.1-0.80.1-0.1-1.81.61.61.6
Locomotor testing distance0.10.30.7-0.8-0.80.7-0.4-0.0-0.00.1
Locomotor testing rearing0.51.83.4-1.4-0.80.9-1.91.31.31.6
Locomotion in novel chamber1.52.03.71.91.8-1.21.7-0.8-0.8-1.3
Locomotion in novel chamber post-restriction0.72.04.12.01.5-1.41.7-0.8-0.8-1.3
Fecal boli incidents, locomotor time 10.00.10.2-0.1-0.20.10.4-0.3-0.3-0.5
Change in fecal boli incidents, locomotor task0.90.91.40.40.7-0.8-1.11.11.11.2
Time >=10cm from walls, locomotor time 10.10.10.30.30.3-0.50.2-0.0-0.0-0.2
Bouts of movement, locomotor time 11.11.42.5-0.00.4-0.4-1.51.61.61.5
Total resting periods, locomotor time 10.80.91.50.30.5-0.7-1.01.21.21.1
Rest time, locomotor task time 10.00.00.10.20.1-0.4-0.20.10.10.3
Distance moved, locomotor task time 10.10.20.5-0.6-0.70.30.0-0.5-0.5-0.3
Vertical activity count, locomotor time 10.00.10.3-0.6-0.40.3-0.2-0.0-0.00.0
Time >=10cm from walls, locomotor time 20.41.12.30.10.1-0.41.3-1.3-1.3-1.5
Bouts of movement, locomotor time 20.62.13.9-0.6-1.51.11.0-2.0-2.0-1.4
Total resting periods, locomotor time 20.31.32.4-0.5-1.30.90.7-1.6-1.6-1.0
Rest time, locomotor task time 20.30.50.90.50.6-0.6-0.50.90.90.6
Distance moved, locomotor task time 20.10.20.30.20.2-0.60.5-0.4-0.4-0.6
Vertical activity count, locomotor time 20.10.20.5-0.1-0.00.10.6-0.7-0.7-0.7
Light reinforcement 10.00.10.4-0.1-0.60.10.1-0.5-0.5-0.1
Light reinforcement 21.22.75.7-0.7-1.40.61.4-2.4-2.4-1.7
Bone: marrow area0.00.00.10.10.3-0.3-0.10.10.1-0.0
Bone: maximum diameter1.42.96.3-2.5-1.71.9-2.10.50.51.6
Bone: maximum force0.10.10.2-0.4-0.40.4-0.30.10.10.3
Bone: maximum moment0.10.20.4-0.6-0.60.6-0.4-0.0-0.00.2
Mean time between licks in bursts0.10.91.6-0.8-0.10.3-1.31.11.11.2
Mean num. licks in bursts1.33.56.72.32.6-2.6-0.31.51.51.0
Cd content in liver0.60.71.3-0.6-0.40.5-1.11.01.01.0
Co content in liver0.20.20.4-0.6-0.50.2-0.60.40.40.5
Cu content in liver0.40.40.7-0.40.10.1-0.80.80.80.8
Fe content in liver0.91.12.01.20.9-1.21.4-0.6-0.6-1.1
K content in liver3.02.95.7-1.9-2.22.40.5-1.6-1.6-0.9
Mg content in liver0.30.31.2-0.7-0.71.1-0.1-0.3-0.3-0.1
Mn content in liver0.60.61.7-0.6-0.91.30.4-0.8-0.8-0.5
Na content in liver1.11.23.1-1.8-1.41.4-1.00.10.10.7
Rb content in liver0.70.81.8-1.3-1.11.2-0.80.20.20.4
Se content in liver1.41.64.5-1.5-1.82.1-0.1-0.8-0.8-0.1
Sr content in liver2.01.84.3-2.1-1.61.8-1.20.20.20.7
Zn content in liver1.21.42.2-1.1-1.51.10.6-1.4-1.4-1.0
Bone: minimum diameter0.10.30.50.0-0.10.10.6-0.7-0.7-0.7
Time in familiar zone, hab. session 10.10.10.30.60.3-0.40.2-0.1-0.10.0
Time in novel zone, hab. session 10.20.30.4-0.6-0.30.4-0.60.50.50.5
Total zone transitions, hab. session 10.00.00.0-0.10.10.1-0.1-0.2-0.20.1
Total locomotion distance, hab. session 10.50.61.3-0.4-0.70.70.6-1.1-1.1-0.7
Locomotion velocity, hab. session 10.20.30.7-0.2-0.40.40.5-0.8-0.8-0.6
Time in familiar zone, hab. session 21.11.33.01.61.3-1.71.0-0.1-0.1-0.8
Time in novel zone, hab. session 21.81.93.2-1.6-1.21.8-1.70.80.81.5
Total zone transitions, hab. session 20.81.12.3-1.2-1.31.50.0-1.0-1.0-0.3
Total locomotion distance, hab. session 20.70.91.9-1.0-1.21.4-0.1-0.9-0.9-0.1
Locomotion velocity, hab. session 21.11.52.6-1.3-1.51.60.1-1.3-1.3-0.5
Novel to familiar place preference ratio0.40.51.2-0.60.10.1-1.10.80.81.0
Novelty place preference0.50.61.3-0.60.10.1-1.20.90.91.0
Time in novel zone, NPP test0.70.81.6-0.60.10.1-1.31.11.11.2
Total zone transitions, NPP test1.11.62.80.3-0.50.51.6-1.7-1.7-1.5
Total locomotion distance, NPP test1.42.03.5-0.2-1.11.11.4-1.9-1.9-1.5
Locomotion velocity, NPP test1.52.13.8-0.4-1.31.11.4-2.0-2.0-1.6
Intraocular pressure0.20.30.5-0.7-0.40.1-0.70.40.40.6
Delta distance traveled before/after self-admin0.91.01.80.4-0.1-0.61.2-1.3-1.3-1.2
Delta ambulatory time before/after self-admin0.50.91.60.4-0.1-0.41.2-1.2-1.2-1.1
Parametrial fat weight0.92.24.9-1.8-1.20.6-2.20.90.91.8
Pavlov. Cond. lever latency0.40.50.9-0.30.2-0.4-0.91.01.00.8
Pavlov. Cond. magazine entry latency0.70.93.01.71.1-0.81.1-0.2-0.2-0.6
Pavlov. Cond. change in total contacts0.70.71.7-0.9-1.11.3-0.90.10.10.9
Pavlov. Cond. index score0.81.02.11.50.5-0.41.4-0.8-0.8-1.0
Pavlov. Cond. latency score0.70.91.91.20.4-0.21.4-0.9-0.9-1.1
Pavlov. Cond. lever contacts0.60.71.30.80.00.11.1-1.0-1.0-0.9
Pavlov. Cond. magazine entry number0.70.93.5-1.9-1.20.8-0.8-0.1-0.10.2
Pavlov. Cond. intertrial magazine entries2.12.63.9-1.3-1.51.61.1-2.0-2.0-1.6
Pavlov. Cond. lever-magazine prob. diff.1.01.22.61.60.6-0.41.6-0.9-0.9-1.2
Pavlov. Cond. response bias0.30.41.21.10.30.10.9-0.6-0.6-0.5
Pavlov. Cond. lever latency2.73.87.9-2.6-2.82.7-0.3-1.4-1.4-0.4
Pavlov. Cond. magazine entry latency0.10.10.50.40.7-0.4-0.10.20.20.2
Pavlov. Cond. change in total contacts0.10.30.60.60.8-0.80.10.30.30.0
Pavlov. Cond. index score0.81.33.01.51.7-1.60.30.70.70.1
Pavlov. Cond. latency score0.71.12.71.61.6-1.40.50.40.4-0.1
Pavlov. Cond. lever contacts2.63.98.52.72.9-2.80.51.31.30.2
Pavlov. Cond. magazine entry number1.01.31.8-0.8-1.31.10.8-1.3-1.3-1.1
Pavlov. Cond. intertrial magazine entries0.00.10.3-0.2-0.50.40.10.00.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.91.43.31.61.8-1.60.30.70.70.1
Pavlov. Cond. response bias2.12.95.92.02.4-2.4-0.11.41.40.6
Time in closed arm before self-admin0.20.31.2-0.7-1.10.6-0.2-0.2-0.20.1
Time in closed arm after self-admin1.71.93.21.40.6-1.21.8-1.3-1.3-1.7
Time in open arm before self-admin0.50.60.80.90.8-0.70.9-0.6-0.6-0.7
Time in open arm after self-admin0.50.61.1-0.6-0.00.1-1.00.90.90.9
Bone: periosteal estimation0.20.41.2-1.1-0.80.9-0.4-0.3-0.30.1
Bone: periosteal perimeter0.71.42.9-1.7-1.61.5-0.2-1.0-1.0-0.3
Bone: post-yield work0.00.00.0-0.1-0.00.1-0.10.00.00.1
Progressive ratio test 1 active lever presses0.40.71.3-1.0-1.10.6-0.0-0.9-1.0-0.3
Progressive ratio test 1 breakpoint0.40.71.4-1.0-1.20.50.0-1.0-1.0-0.3
Progressive ratio test 1 inactive lever presses1.53.99.2-3.0-2.72.3-0.7-1.6-1.6-0.1
Progressive ratio test 2 active lever presses0.30.51.0-1.0-0.90.7-0.70.30.30.6
Progressive ratio test 2 breakpoint0.30.40.8-0.9-0.80.6-0.70.40.40.6
Progressive ratio test 2 inactive lever presses0.30.92.3-1.4-1.50.8-0.4-0.8-0.80.1
Incentive Sensitization - Responses0.10.20.4-0.4-0.20.3-0.60.60.60.5
Incentive Sensitization - Breakpoint0.10.30.6-0.2-0.10.2-0.60.80.80.6
Sum of active levers in priming session hrs 5-60.90.92.4-1.0-1.31.60.0-0.7-0.7-0.2
Progressive ratio0.30.81.60.1-0.4-0.31.0-1.3-1.3-1.1
Food seeking constrained by brief footshock3.03.87.2-2.1-2.32.70.2-2.1-2.1-0.8
Seeking ratio, punishment vs. effort0.41.03.6-1.2-1.11.9-0.3-0.5-0.50.1
Retroperitoneal fat weight0.20.81.6-1.3-0.90.7-1.30.40.41.0
Reaction time number correct0.20.61.20.40.5-0.5-0.81.11.10.9
Reaction time mean minus median0.42.55.11.82.1-2.3-0.21.41.40.6
Reaction time mean minus median AUC0.31.93.61.61.9-1.8-0.11.41.40.5
Reaction time num false alarms0.61.03.4-0.8-1.41.80.0-0.6-0.6-0.1
Reaction time num false alarms AUC0.61.43.8-0.9-1.61.90.4-1.0-1.0-0.5
Reaction time trials correct on left0.20.61.20.40.5-0.5-0.81.11.10.9
Reaction time trials on left0.20.71.20.40.5-0.6-0.81.11.10.9
Reaction time mean0.20.51.50.80.7-1.20.70.00.0-0.6
Reaction time mean AUC0.30.71.71.00.9-1.31.0-0.2-0.2-0.8
Median of all reaction times0.30.40.80.40.2-0.70.9-0.5-0.5-0.9
Reaction time omissions0.50.82.31.21.0-1.50.60.40.4-0.4
Reaction time false alarm rate1.42.04.3-1.0-1.72.10.7-1.5-1.5-0.9
Reaction time premature initiation rate1.32.03.61.61.0-1.01.9-1.3-1.3-1.6
Reaction time premature initiations0.30.81.91.41.0-1.01.0-0.4-0.4-0.7
Std. dev. reaction times0.41.43.51.41.6-1.90.20.90.90.1
Reaction time trials completed0.20.71.20.40.5-0.6-0.81.11.10.9
Reaction time trials AUC0.20.51.00.30.3-0.4-0.81.01.00.9
Run reversals in cocaine runway, females0.40.50.80.50.5-0.60.9-0.7-0.7-0.8
Run reversals in cocaine runway, males0.10.10.3-0.5-0.10.3-0.50.30.30.3
Latency to leave start box in cocaine runway0.20.30.7-0.8-0.70.90.2-0.4-0.4-0.3
Latency to leave start box in cocaine runway, F0.81.02.6-1.5-1.31.6-0.3-0.4-0.4-0.0
Latency to leave start box in cocaine runway, M0.30.30.40.70.5-0.60.6-0.3-0.3-0.6
Std. dev. time between licks in bursts0.10.20.40.10.1-0.1-0.40.60.60.5
Total sessions with >9 infusions0.50.60.90.70.9-0.51.0-0.7-0.7-0.9
Short access day 1 total inactive lever presses1.12.35.7-2.4-1.92.2-1.2-0.2-0.20.6
Short access day 10 total inactive lever presses0.00.20.4-0.5-0.60.40.0-0.5-0.5-0.1
Short access day 1 total infusions0.40.91.40.50.6-0.31.1-1.2-1.2-1.1
Short access day 10 total infusions0.20.40.70.30.30.00.8-0.8-0.8-0.8
Short access total infusions0.10.20.3-0.3-0.10.50.3-0.5-0.5-0.4
Short access day 1 locomotion1.42.44.70.70.6-0.31.8-2.2-2.2-1.8
Short access day 10 total locomotion0.93.87.51.20.5-1.22.1-2.7-2.7-2.1
Short access total locomotion1.21.82.51.10.9-1.01.6-1.5-1.5-1.5
One hour access (0.3 mA shock)0.60.71.5-1.2-1.20.9-0.5-0.6-0.60.3
Compulsive drug intake0.61.02.41.21.6-1.11.0-0.1-0.1-0.7
One hour access (shock baseline)0.30.71.8-1.2-1.40.7-0.7-0.3-0.30.4
Social response proportion0.70.92.4-1.5-1.61.0-0.6-0.4-0.40.2
Social responses0.91.22.1-1.4-1.30.7-1.40.60.61.2
Social time0.10.10.2-0.3-0.4-0.0-0.40.30.30.3
Soleus weight1.03.05.7-2.1-2.42.00.4-1.6-1.6-1.1
Bone: stiffness0.10.10.30.50.6-0.50.10.20.20.0
Tibialis anterior weight0.51.73.0-1.6-1.31.3-1.70.50.51.4
Time to tail flick, vehicle, before self-admin1.31.63.9-0.3-0.80.61.0-2.0-2.0-1.2
Time to tail flick, vehicle, after self-admin0.20.40.80.1-0.4-0.00.7-0.9-0.9-0.7
Time to tail flick, test, before self-admin0.50.61.50.10.50.1-0.51.21.20.6
Time to tail flick, test, after self-admin2.32.45.5-2.0-2.42.0-0.5-1.2-1.2-0.0
Delta time to tail flick, vehicle, before/after SA0.10.10.20.20.4-0.40.4-0.1-0.1-0.4
Delta time to tail flick, test, before/after SA0.70.92.4-1.1-1.50.7-0.3-1.0-1.0-0.0
Tibia length0.61.83.3-0.4-1.30.51.6-1.5-1.5-1.8
Ambulatory time before self-admin0.10.20.5-0.4-0.20.4-0.70.50.50.6
Ambulatory time after self-admin0.20.30.7-0.2-0.40.10.5-0.9-0.9-0.6
Bone: tissue strength1.51.52.60.41.2-1.1-1.11.61.61.2
Total heroin consumption0.10.10.4-0.2-0.60.20.1-0.3-0.3-0.1
Bone: trabecular number0.00.00.10.0-0.20.00.10.10.1-0.1
Bone: trabecular spacing0.40.61.7-1.3-0.81.0-0.80.10.10.5
Bone: trabecular thickness0.81.22.40.90.2-0.71.6-1.1-1.1-1.4
Bone: trabecular tissue density0.61.12.81.21.7-1.4-0.20.80.80.6
Water consumed over 24 hours1.01.93.8-0.60.10.3-1.91.61.62.0
Number of responses in last shaping day0.40.51.00.20.2-0.60.8-1.0-1.0-0.8