Hub : Genes

Unc93b1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Unc93b1 0.06 0.04 8.8e-06 0.05 0.04 0.04 0.04 7.0e-06 7.1e-05 2.8e-05 2.0e-05
2 NAcc gene expression Unc93b1 0.02 0.02 5.0e-03 0.01 0.01 -0 0 2.4e-02 3.8e-02 4.9e-01 8.9e-02
3 Brain gene expression Unc93b1 0.07 0.05 2.0e-06 0.04 0.05 0.06 0.04 2.0e-04 2.8e-05 6.6e-06 1.1e-04
4 BLA gene expression Unc93b1 0.06 0.04 6.2e-03 0.02 0.03 0.01 0.02 4.6e-02 1.1e-02 6.6e-02 2.5e-02
5 IL alternative TSS NM_001403514.1 0.2 0.13 4.9e-03 0.06 0.02 0.04 0.03 1.7e-02 9.5e-02 4.7e-02 5.8e-02
6 pVTA alternative TSS XM_039083685.1 0.08 0.06 1.3e-03 0.02 0.04 0.03 0.02 5.5e-02 1.2e-02 2.1e-02 3.1e-02
7 pVTA alternative TSS NM_001403514.1 0.08 0.06 1.3e-03 0.01 0.03 0.03 0.02 8.1e-02 1.6e-02 2.2e-02 5.0e-02
8 pVTA isoform ratio NM_001403514.1 0.06 0.05 7.2e-03 0.02 0.03 0.06 0.02 5.6e-02 1.7e-02 1.5e-03 3.9e-02
9 pVTA alternative TSS XM_039083685.1 0.06 0.05 6.0e-03 0 0.02 0.02 0 2.3e-01 6.3e-02 4.8e-02 2.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.44.16.6-1.5-1.7-2.42.3-2.6-2.52.5-0.11.1
Area under the delay curve1.01.11.6-1.1-0.8-1.21.2-0.9-1.21.21.20.2
BMI with tail1.65.111.2-0.2-0.2-2.51.9-3.3-2.92.9-0.82.6
BMI without tail0.91.94.50.0-0.1-1.41.1-2.1-1.81.8-0.81.4
Body weight0.72.86.12.52.3-0.3-0.4-2.2-1.11.1-1.71.8
Weight adjusted by age0.50.61.71.11.00.3-0.5-0.4-0.10.1-1.30.9
Bone surface2.23.88.7-0.5-0.7-2.21.8-3.0-2.62.6-0.91.6
Bone volume1.83.15.6-1.1-1.3-2.11.9-2.4-2.32.30.01.0
Breakpoint value in progressive ratio session0.50.51.10.91.00.0-0.2-0.9-0.40.4-1.00.7
Number of licking bursts0.10.10.1-0.2-0.2-0.30.3-0.4-0.40.40.10.0
Context. condit. distance diff. score0.40.51.4-1.2-1.0-0.50.70.1-0.30.31.2-0.4
Locomotion velocity, session 10.00.00.00.0-0.1-0.10.1-0.1-0.10.1-0.10.1
Locomotion distance, session 11.41.83.1-0.8-0.8-1.51.4-1.7-1.71.7-0.51.2
Locomotion velocity, session 20.60.71.91.41.10.2-0.5-0.6-0.10.1-1.40.8
Locomotion distance, session 20.60.91.90.10.1-0.80.5-1.2-1.01.0-1.41.3
Locomotion velocity, session 31.51.72.7-1.1-0.9-1.61.5-1.5-1.61.60.50.8
Locomotion distance, session 30.10.10.2-0.3-0.2-0.50.4-0.4-0.40.40.10.4
Stereotopy head waving bouts, day 31.41.72.5-1.5-1.3-1.51.6-1.2-1.41.41.00.3
Stereotopy head waving duration, day 31.01.12.6-1.6-1.4-1.01.3-0.6-0.90.91.0-0.1
Locomotion velocity, session 71.11.21.9-1.0-0.8-1.41.3-1.2-1.31.3-0.21.0
Locomotion distance, session 70.30.41.80.10.1-0.40.3-0.6-0.50.5-1.30.9
Stereotopy head waving bouts, day 71.41.62.7-1.6-1.3-1.41.5-1.0-1.31.31.30.3
Stereotopy head waving duration, day 71.41.73.4-0.8-0.5-1.61.4-1.8-1.71.70.60.9
Locomotion velocity, session 80.30.31.01.00.90.1-0.3-0.6-0.20.2-0.50.4
Locomotion distance, session 80.30.40.8-0.9-0.8-0.70.8-0.5-0.60.60.20.2
Degree of sensitization distance0.40.41.2-0.1-0.2-0.60.5-0.7-0.70.7-1.10.8
Degree of sensitization stereotypy0.60.71.2-0.6-0.3-0.90.9-1.1-1.01.00.60.4
Conditioned locomotion2.63.05.92.42.31.9-2.11.01.5-1.5-1.6-0.1
Cocaine response after cond. corrected0.10.10.4-0.4-0.4-0.20.3-0.1-0.20.20.6-0.2
Cocaine response after cond. not corrected0.40.40.6-0.8-0.8-0.80.8-0.5-0.70.70.50.2
Cocaine response before conditioning0.20.20.4-0.2-0.2-0.60.4-0.5-0.50.5-0.40.6
Saline control response0.50.71.61.31.20.1-0.3-0.9-0.40.4-1.10.7
Bone: connectivity density2.74.29.0-0.6-0.9-2.31.9-3.0-2.72.7-1.21.7
Bone: cortical apparent density0.40.51.90.91.00.5-0.60.00.3-0.3-1.40.6
Bone: cortical area0.50.81.51.21.11.1-1.10.50.8-0.8-0.4-0.4
Bone: cortical porosity0.30.31.7-0.2-0.2-0.30.3-0.3-0.30.31.3-0.3
Bone: cortical porosity0.10.10.60.30.3-0.1-0.1-0.3-0.20.20.7-0.1
Bone: cortical thickness3.25.211.13.33.32.4-2.70.91.7-1.7-2.2-0.1
Bone: cortical thickness1.51.75.01.81.71.2-1.30.20.7-0.7-2.20.4
Bone: cortical tissue density0.50.62.01.01.10.6-0.70.10.3-0.3-1.40.6
Condit. Reinf. active minus inactive responses0.40.40.7-0.4-0.4-0.80.7-0.8-0.80.8-0.10.7
Condit. Reinf. active-inactive response ratio0.30.30.5-0.5-0.5-0.70.6-0.5-0.60.60.30.4
Condit. Reinf. active responses0.10.10.2-0.1-0.2-0.40.2-0.2-0.30.3-0.20.5
Condit. Reinf. inactive responses0.00.00.10.20.00.2-0.20.30.3-0.30.0-0.1
Incentive salience index mean0.30.30.5-0.2-0.3-0.70.5-0.7-0.70.7-0.40.7
Condit. Reinf. lever presses0.10.10.60.30.20.2-0.30.20.2-0.2-0.80.3
Condit. Reinf. active minus inactive responses1.41.82.7-1.6-1.6-1.61.6-1.0-1.41.40.80.5
Condit. Reinf. active-inactive response ratio1.21.22.8-1.7-1.7-1.11.3-0.3-0.70.71.2-0.2
Condit. Reinf. active responses1.62.33.6-1.4-1.4-1.91.8-1.6-1.81.80.50.9
Condit. Reinf. inactive responses0.81.02.2-0.2-0.2-1.20.9-1.5-1.31.3-0.31.0
Condit. Reinf. lever presses0.60.92.1-0.2-0.2-1.00.9-1.4-1.31.3-0.30.8
Condit. Reinf. lever reinforcers received1.62.33.6-1.3-1.2-1.91.7-1.7-1.81.80.31.0
Conditioned reinforcement - actives0.40.40.90.10.30.5-0.60.90.9-0.90.4-0.3
Conditioned reinforcement - inactives1.21.43.8-2.0-1.8-0.50.61.20.5-0.51.4-0.8
Conditioned locomotion2.32.76.9-1.3-1.40.9-0.52.61.8-1.81.9-1.6
Patch foraging indifference point 0 sec0.40.64.2-0.7-0.6-0.30.40.1-0.10.12.0-0.6
Patch foraging indifference point AUC0.70.82.71.51.60.9-1.00.20.5-0.50.3-0.1
Delay disc. indifference point, 0s delay1.81.92.7-1.3-1.1-1.61.6-1.5-1.61.61.30.4
Delay disc. indifference point, 16s delay0.70.72.2-1.3-1.1-0.40.70.2-0.30.31.5-0.3
Delay disc. indifference point, 2s delay0.60.71.2-1.1-1.1-0.91.0-0.6-0.80.80.70.1
Delay disc. indifference point, 24s delay0.40.40.60.50.70.5-0.60.40.5-0.50.8-0.6
Delay disc. indifference point, 4s delay0.50.51.4-0.6-0.5-0.70.7-0.6-0.70.71.20.2
Delay disc. indifference point, 8s delay0.40.40.6-0.5-0.1-0.80.7-0.7-0.70.70.70.1
Indifference point function ln k0.81.13.2-1.8-1.7-0.20.51.10.5-0.50.9-1.0
Indifference point function log k0.81.13.2-1.8-1.7-0.20.51.10.5-0.50.9-1.0
Patch foraging total patch changes 0 sec0.30.63.8-0.10.00.3-0.20.40.4-0.41.9-0.8
Patch foraging total patch changes 12 sec0.50.62.41.31.60.3-0.5-0.6-0.10.10.80.1
Patch foraging total patch changes 18 sec0.20.21.20.20.3-0.10.1-0.5-0.30.31.10.0
Patch foraging total patch changes 24 sec0.50.61.81.21.30.8-0.90.30.5-0.50.5-0.5
Patch foraging total patch changes 6 sec0.40.51.30.10.3-0.70.5-1.1-0.90.90.80.5
Patch foraging time to switch 0 sec2.23.36.3-0.6-0.6-2.01.7-2.5-2.32.3-1.51.9
Patch foraging water rate 0 sec3.25.110.60.1-0.02.3-1.73.32.8-2.82.4-2.6
Patch foraging water rate 12 sec3.75.611.7-0.1-0.32.3-1.73.42.9-2.92.3-2.9
Patch foraging water rate 18 sec0.60.81.6-0.5-0.70.7-0.41.21.0-1.00.9-1.2
Patch foraging water rate 24 sec2.13.06.30.30.01.9-1.52.52.2-2.21.1-1.9
Patch foraging water rate 6 sec1.82.65.20.50.31.8-1.52.32.1-2.10.7-1.8
Seeking ratio, delayed vs. immediate footshock0.60.71.2-0.7-0.4-0.91.0-1.1-1.11.1-0.10.7
Distance traveled before self-admin0.10.10.2-0.1-0.1-0.10.3-0.4-0.40.4-0.3-0.2
Distance traveled after self-admin0.50.64.3-0.0-0.3-0.10.2-0.3-0.20.2-2.10.8
Extensor digitorum longus weight1.76.918.64.34.21.4-2.2-1.20.2-0.2-3.71.8
Bone: elastic displacement2.83.14.61.31.32.2-2.02.12.1-2.10.6-1.5
Bone: elastic work1.62.04.12.02.01.7-1.80.81.3-1.3-0.3-0.6
Bone: endosteal estimation1.43.16.6-2.3-2.6-1.82.0-0.8-1.31.32.1-0.1
Bone: endosteal perimeter2.96.112.5-3.3-3.5-2.42.8-1.1-1.81.83.1-0.3
Epididymis fat weight0.81.84.5-2.1-2.0-0.50.91.00.3-0.32.1-0.8
Delta time in closed arm before/after self-admin0.80.81.71.31.20.6-0.90.30.6-0.61.0-0.9
Delta time in open arm before/after self-admin0.30.20.6-0.7-0.8-0.30.4-0.1-0.20.2-0.60.6
Diff in mean of infusions in LGA sessions0.20.30.80.70.90.6-0.50.00.2-0.2-0.2-0.5
Delay discount exponential model param0.80.81.60.90.61.1-1.00.81.0-1.0-1.2-0.1
Extinction: sum of active levers before priming1.11.12.31.00.6-0.30.2-1.5-1.11.0-1.51.4
Active lever presses in extinction session 61.41.42.81.71.61.2-1.50.61.1-1.1-0.4-0.5
Bone: final force0.40.61.40.80.7-0.20.1-1.1-0.70.7-1.20.6
Bone: final moment0.30.41.00.80.7-0.10.0-1.0-0.60.6-0.90.5
Food consumed during 24 hour testing period0.20.30.60.0-0.10.6-0.40.70.6-0.60.4-0.7
Glucose1.82.75.6-2.3-2.4-1.82.0-0.9-1.41.40.70.6
Heart weight0.50.71.7-1.3-1.2-0.60.80.3-0.30.31.2-0.3
Delay discount hyperbolic model param0.80.81.50.90.71.1-1.00.81.0-1.0-1.2-0.0
Intermittent access intake day 1-15 change0.50.51.3-0.5-0.40.5-0.31.10.8-0.80.5-1.0
Intermittent access intake escalation0.30.30.6-0.8-0.70.10.10.80.4-0.40.4-0.7
Intermittent access intake escalation 20.20.20.6-0.2-0.20.4-0.20.80.6-0.6-0.5-0.1
Intermitt. access day 1 inactive lever presses0.40.41.6-1.2-1.0-0.30.50.4-0.00.00.50.5
Intermitt. access day 15 inactive lever presses0.70.82.5-1.6-1.5-0.81.00.1-0.40.4-0.00.4
Intermitt. access escalation Index1.31.14.0-0.8-0.80.5-0.11.10.7-0.72.0-1.5
Intermittent access day 1 total infusions4.34.910.8-3.3-2.9-2.62.7-1.3-2.02.00.11.2
Intermittent access day 15 total infusions2.32.59.5-3.1-2.6-1.41.70.4-0.50.50.9-0.1
Intermittent access terminal intake (last 3 days)2.32.58.4-2.9-2.4-1.71.9-0.1-0.90.90.50.3
Intermittent access total infusions2.22.57.2-2.7-2.2-1.81.9-0.5-1.11.10.60.7
Intermittent access day 1 locomotion3.13.35.9-2.4-2.0-2.12.1-1.2-1.71.70.01.8
Intermittent access day 15 total locomotion1.41.64.8-2.2-2.2-1.11.20.4-0.30.41.2-0.4
Intermittent access total locomotion3.43.910.6-3.3-3.0-2.12.3-0.5-1.31.30.90.6
Intermittent access standard deviation0.20.20.5-0.6-0.4-0.10.10.60.3-0.30.6-0.7
Left kidney weight0.61.76.0-0.3-0.50.8-0.51.61.2-1.22.4-1.6
Right kidney weight0.82.24.20.10.11.3-1.12.01.7-1.72.0-1.6
Cocaine induced anxiety0.00.00.30.3-0.2-0.1-0.00.10.1-0.1-0.0-0.5
Post-drug Anxiety0.70.82.31.51.30.8-1.00.20.6-0.6-0.6-0.6
Baseline Anxiety0.90.92.61.61.61.0-1.10.00.5-0.5-0.80.2
Tail length0.92.85.62.42.31.8-1.90.91.4-1.4-1.7-0.3
Length with tail1.14.211.63.43.31.8-2.20.11.1-1.1-2.00.2
Length without tail0.71.55.12.32.10.8-1.2-0.50.3-0.3-0.90.6
Times rat made contact with spout0.50.51.3-0.1-0.2-0.80.7-1.1-1.01.00.60.1
Lifetime Intake2.02.26.1-2.5-2.0-1.81.8-0.5-1.11.10.60.8
Liver weight, left0.00.10.3-0.3-0.40.10.10.20.1-0.1-0.0-0.5
Liver weight, right0.40.60.90.50.50.7-0.70.90.9-0.90.8-0.9
Locomotor activity0.40.61.3-0.2-0.30.6-0.41.10.9-0.90.8-1.2
Locomotor testing distance0.50.92.3-0.4-0.30.6-0.41.20.9-0.91.4-1.5
Locomotor testing rearing0.50.82.0-1.4-1.4-0.80.9-0.1-0.50.51.0-0.5
Locomotion in novel chamber1.62.07.1-2.6-2.7-0.91.30.7-0.20.20.8-0.8
Locomotion in novel chamber post-restriction1.21.54.7-1.4-1.4-0.30.40.90.3-0.32.2-1.8
Fecal boli incidents, locomotor time 10.10.10.2-0.3-0.4-0.10.10.2-0.00.00.4-0.2
Change in fecal boli incidents, locomotor task0.10.10.30.10.3-0.50.2-0.5-0.50.5-0.20.3
Time >=10cm from walls, locomotor time 12.92.95.1-2.2-2.2-2.22.1-1.0-1.61.60.30.8
Bouts of movement, locomotor time 10.91.02.11.51.20.9-1.10.50.8-0.80.7-1.3
Total resting periods, locomotor time 10.70.81.51.20.90.9-1.00.60.8-0.80.6-1.2
Rest time, locomotor task time 11.11.22.8-0.0-0.10.9-0.81.71.3-1.30.8-1.6
Distance moved, locomotor task time 11.11.21.8-0.9-0.7-1.11.2-1.2-1.31.3-0.71.4
Vertical activity count, locomotor time 10.60.62.0-1.4-1.0-0.61.0-0.3-0.60.6-0.00.6
Time >=10cm from walls, locomotor time 20.10.20.40.2-0.10.4-0.30.70.5-0.5-0.00.5
Bouts of movement, locomotor time 20.20.20.60.80.70.3-0.50.00.2-0.20.20.5
Total resting periods, locomotor time 20.10.10.20.40.30.1-0.2-0.1-0.00.00.40.4
Rest time, locomotor task time 21.31.43.3-1.8-1.7-1.21.3-0.2-0.70.71.3-1.0
Distance moved, locomotor task time 20.70.81.61.21.31.1-1.00.40.7-0.7-1.00.4
Vertical activity count, locomotor time 22.22.44.11.51.62.0-1.81.51.8-1.8-0.6-0.2
Light reinforcement 10.30.61.9-0.3-0.20.6-0.30.90.7-0.71.4-1.1
Light reinforcement 20.91.23.9-0.9-0.80.5-0.21.20.9-0.92.0-1.3
Bone: marrow area1.43.16.6-2.3-2.6-1.82.0-0.8-1.31.32.1-0.1
Bone: maximum diameter0.10.20.6-0.0-0.20.3-0.20.50.4-0.40.8-0.6
Bone: maximum force1.32.35.7-0.3-0.4-1.61.4-2.4-2.12.1-0.21.1
Bone: maximum moment1.11.94.7-0.2-0.4-1.51.3-2.2-1.91.90.01.0
Mean time between licks in bursts0.30.41.01.00.90.3-0.5-0.30.1-0.1-0.90.3
Mean num. licks in bursts0.10.10.6-0.2-0.2-0.40.3-0.4-0.30.30.8-0.1
Cd content in liver0.40.51.0-0.6-0.70.3-0.11.00.6-0.61.0-0.8
Co content in liver0.91.01.80.60.71.2-1.11.31.3-1.30.4-0.8
Cu content in liver0.10.10.30.50.60.3-0.40.10.2-0.2-0.30.3
Fe content in liver0.00.00.10.20.20.0-0.1-0.20.0-0.0-0.20.1
K content in liver1.31.22.9-0.3-0.3-1.31.1-1.7-1.61.60.30.8
Mg content in liver3.23.24.6-1.6-1.6-2.12.1-1.9-2.12.11.10.9
Mn content in liver0.30.30.60.80.6-0.1-0.1-0.7-0.40.4-0.80.8
Na content in liver0.40.40.60.50.60.8-0.70.60.7-0.70.2-0.7
Rb content in liver2.53.14.8-2.1-2.2-2.12.1-1.2-1.71.71.40.6
Se content in liver0.80.91.4-1.2-1.1-1.21.2-0.8-1.01.00.40.2
Sr content in liver1.71.63.11.71.81.2-1.40.40.9-0.9-1.80.2
Zn content in liver0.30.30.80.80.80.3-0.4-0.2-0.00.0-0.90.3
Bone: minimum diameter2.03.86.2-2.3-2.5-2.12.2-1.4-1.81.82.20.1
Time in familiar zone, hab. session 10.40.30.8-0.8-0.9-0.70.7-0.3-0.50.50.10.3
Time in novel zone, hab. session 10.10.10.10.30.30.3-0.30.20.2-0.20.3-0.3
Total zone transitions, hab. session 10.30.41.30.20.2-0.30.2-0.7-0.50.5-1.20.9
Total locomotion distance, hab. session 10.20.30.9-0.9-0.9-0.50.6-0.0-0.30.3-0.60.5
Locomotion velocity, hab. session 10.10.10.5-0.5-0.5-0.20.3-0.0-0.10.1-0.70.4
Time in familiar zone, hab. session 20.80.81.61.31.31.1-1.10.50.8-0.8-0.6-0.3
Time in novel zone, hab. session 21.31.32.0-1.2-1.2-1.41.3-1.1-1.21.20.50.6
Total zone transitions, hab. session 23.14.17.6-1.0-1.0-2.32.0-2.8-2.62.6-0.71.9
Total locomotion distance, hab. session 21.41.82.4-1.2-1.3-1.51.5-1.5-1.61.6-0.61.2
Locomotion velocity, hab. session 21.31.82.4-1.4-1.4-1.51.6-1.3-1.51.5-0.41.0
Novel to familiar place preference ratio0.50.50.8-0.5-0.3-0.80.7-0.9-0.80.8-0.60.9
Novelty place preference0.60.60.8-0.7-0.6-0.90.8-0.8-0.90.9-0.40.8
Time in novel zone, NPP test0.60.60.8-0.7-0.6-0.90.9-0.8-0.90.9-0.30.8
Total zone transitions, NPP test1.01.42.6-0.1-0.2-1.10.9-1.6-1.41.4-1.41.4
Total locomotion distance, NPP test0.50.60.8-0.7-0.8-0.80.8-0.7-0.80.8-0.90.8
Locomotion velocity, NPP test0.30.40.7-0.6-0.7-0.60.6-0.5-0.60.6-0.90.7
Intraocular pressure0.91.22.20.50.61.4-1.11.51.4-1.40.4-1.0
Delta distance traveled before/after self-admin0.30.42.60.2-0.20.1-0.10.10.1-0.1-1.60.7
Delta ambulatory time before/after self-admin0.50.53.50.50.20.2-0.30.10.2-0.2-1.90.8
Parametrial fat weight1.22.35.4-2.2-2.3-1.41.6-0.3-1.01.02.0-0.2
Pavlov. Cond. lever latency0.10.10.20.1-0.10.3-0.20.50.4-0.40.3-0.4
Pavlov. Cond. magazine entry latency1.21.52.2-1.3-1.2-1.51.4-1.3-1.41.40.80.5
Pavlov. Cond. change in total contacts0.60.61.2-1.1-1.0-0.90.9-0.5-0.70.70.60.2
Pavlov. Cond. index score0.00.10.2-0.4-0.3-0.20.3-0.1-0.20.20.2-0.1
Pavlov. Cond. latency score0.10.10.3-0.6-0.4-0.40.5-0.3-0.40.40.20.1
Pavlov. Cond. lever contacts0.10.10.1-0.3-0.1-0.30.3-0.3-0.30.3-0.10.2
Pavlov. Cond. magazine entry number0.00.00.10.20.2-0.1-0.0-0.2-0.10.1-0.20.2
Pavlov. Cond. intertrial magazine entries0.50.71.20.40.60.9-0.81.11.0-1.00.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.3-0.2-0.20.2-0.2-0.20.20.10.1
Pavlov. Cond. response bias0.00.00.1-0.4-0.3-0.20.2-0.1-0.10.10.3-0.0
Pavlov. Cond. lever latency0.00.00.10.10.00.2-0.20.30.2-0.2-0.10.0
Pavlov. Cond. magazine entry latency1.21.44.00.30.3-1.10.8-2.0-1.61.6-0.41.0
Pavlov. Cond. change in total contacts0.50.71.5-0.5-0.5-1.00.9-1.2-1.21.20.20.4
Pavlov. Cond. index score0.40.51.5-0.00.1-0.70.6-1.2-1.01.0-0.30.5
Pavlov. Cond. latency score0.30.41.2-0.10.0-0.60.6-1.1-0.90.9-0.20.4
Pavlov. Cond. lever contacts0.00.10.10.30.30.3-0.30.20.3-0.3-0.0-0.2
Pavlov. Cond. magazine entry number1.62.05.1-0.4-0.51.3-0.92.31.8-1.81.2-1.6
Pavlov. Cond. intertrial magazine entries0.30.41.0-0.7-0.60.3-0.11.00.6-0.60.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.80.10.2-0.70.6-1.3-1.11.1-0.50.7
Pavlov. Cond. response bias0.20.30.80.20.3-0.50.3-0.9-0.70.7-0.40.5
Time in closed arm before self-admin0.30.30.6-0.7-0.7-0.40.5-0.3-0.40.4-0.80.8
Time in closed arm after self-admin0.20.20.30.50.40.3-0.50.30.4-0.40.6-0.6
Time in open arm before self-admin0.20.30.70.80.90.5-0.50.10.3-0.30.2-0.4
Time in open arm after self-admin0.10.10.40.30.30.3-0.30.20.2-0.2-0.60.1
Bone: periosteal estimation0.20.31.3-0.6-0.8-0.30.4-0.1-0.20.21.1-0.4
Bone: periosteal perimeter0.40.71.2-0.9-1.1-0.80.9-0.6-0.80.81.0-0.1
Bone: post-yield work7.810.615.4-3.2-3.3-3.93.8-3.4-3.73.71.81.4
Progressive ratio test 1 active lever presses0.30.30.9-1.0-0.6-0.20.20.70.4-0.40.50.2
Progressive ratio test 1 breakpoint0.20.30.7-0.8-0.4-0.0-0.00.80.5-0.50.60.2
Progressive ratio test 1 inactive lever presses0.20.20.8-0.7-0.5-0.50.40.2-0.10.10.30.9
Progressive ratio test 2 active lever presses0.60.72.5-1.6-1.2-0.70.60.70.1-0.10.9-0.1
Progressive ratio test 2 breakpoint0.70.81.9-1.4-1.0-0.20.21.20.6-0.61.1-0.6
Progressive ratio test 2 inactive lever presses2.12.48.6-2.9-2.6-1.31.60.6-0.40.41.00.6
Incentive Sensitization - Responses0.10.10.3-0.5-0.5-0.50.30.0-0.10.1-0.10.0
Incentive Sensitization - Breakpoint0.10.10.4-0.6-0.6-0.50.30.2-0.10.1-0.0-0.1
Sum of active levers in priming session hrs 5-63.02.94.21.81.62.0-2.01.72.0-2.0-1.1-0.6
Progressive ratio3.13.67.5-0.7-0.8-2.01.8-2.7-2.52.5-1.11.8
Food seeking constrained by brief footshock0.40.52.50.10.50.10.0-0.4-0.30.3-1.61.2
Seeking ratio, punishment vs. effort1.82.24.90.50.81.8-1.52.22.0-2.00.4-0.9
Retroperitoneal fat weight1.34.110.7-3.3-3.2-0.71.31.50.3-0.33.0-1.6
Reaction time number correct0.60.81.81.31.01.1-1.10.60.9-0.9-0.3-0.6
Reaction time mean minus median1.11.44.50.50.6-0.70.3-1.2-1.01.0-2.11.9
Reaction time mean minus median AUC0.81.04.21.11.20.0-0.4-0.4-0.20.2-2.11.3
Reaction time num false alarms0.81.01.51.11.11.2-1.21.01.1-1.1-0.2-0.6
Reaction time num false alarms AUC0.71.02.11.41.51.1-1.10.50.8-0.8-0.8-0.2
Reaction time trials correct on left0.60.81.81.31.01.1-1.10.60.9-0.9-0.3-0.6
Reaction time trials on left0.71.02.21.51.21.2-1.30.60.9-0.9-0.3-0.5
Reaction time mean0.60.92.3-0.6-0.6-0.90.8-0.6-0.80.8-1.51.3
Reaction time mean AUC0.70.92.0-0.8-0.7-1.00.9-0.6-0.80.8-1.41.3
Median of all reaction times0.71.01.3-1.0-1.0-1.01.0-0.6-0.90.9-1.11.2
Reaction time omissions0.60.92.71.41.20.3-0.6-0.5-0.10.0-1.71.1
Reaction time false alarm rate0.20.30.80.70.90.6-0.60.50.6-0.6-0.3-0.2
Reaction time premature initiation rate0.91.23.41.61.50.3-0.7-0.7-0.10.1-1.90.9
Reaction time premature initiations1.62.36.62.62.31.1-1.5-0.30.5-0.5-2.10.6
Std. dev. reaction times0.60.93.50.10.1-0.70.4-0.7-0.70.7-1.91.6
Reaction time trials completed0.71.02.21.51.21.2-1.30.60.9-0.9-0.3-0.5
Reaction time trials AUC0.50.71.61.31.01.1-1.10.50.8-0.8-0.2-0.5
Run reversals in cocaine runway, females1.91.93.1-0.4-0.7-1.41.1-1.7-1.61.6-1.41.8
Run reversals in cocaine runway, males1.01.01.31.10.91.1-1.20.91.0-1.0-1.1-0.5
Latency to leave start box in cocaine runway1.11.21.8-1.1-1.2-1.31.3-1.1-1.31.3-0.20.8
Latency to leave start box in cocaine runway, F0.80.81.1-0.7-1.0-0.91.1-1.0-1.11.1-0.50.8
Latency to leave start box in cocaine runway, M0.00.00.1-0.3-0.1-0.30.2-0.1-0.20.2-0.10.1
Std. dev. time between licks in bursts1.41.72.61.61.51.4-1.61.01.3-1.3-1.2-0.2
Total sessions with >9 infusions0.40.51.2-1.1-0.9-0.90.7-0.1-0.40.40.70.2
Short access day 1 total inactive lever presses0.70.83.1-1.8-1.3-0.40.80.4-0.10.10.01.0
Short access day 10 total inactive lever presses0.50.51.5-1.2-1.1-0.20.60.2-0.20.2-0.71.0
Short access day 1 total infusions1.51.64.3-2.1-1.7-1.41.5-0.4-0.90.90.21.1
Short access day 10 total infusions3.53.96.6-2.4-2.1-2.62.3-1.7-2.12.10.11.1
Short access total infusions1.41.63.0-1.7-1.3-1.71.5-0.9-1.21.20.20.9
Short access day 1 locomotion1.51.63.5-1.9-1.7-1.41.4-0.5-1.01.01.10.5
Short access day 10 total locomotion0.91.02.1-1.5-1.3-1.21.2-0.6-0.90.90.20.7
Short access total locomotion1.01.02.1-1.4-1.1-1.21.1-0.6-0.90.90.51.2
One hour access (0.3 mA shock)1.61.97.3-2.7-2.3-0.81.21.00.1-0.11.3-0.1
Compulsive drug intake1.61.75.12.22.31.2-1.50.10.7-0.7-0.30.1
One hour access (shock baseline)1.82.18.3-2.9-2.4-0.71.21.20.2-0.21.2-0.2
Social response proportion0.60.61.20.2-0.2-0.90.5-1.1-0.90.9-0.61.1
Social responses0.20.31.11.00.80.3-0.60.20.3-0.30.10.1
Social time0.10.10.40.60.5-0.1-0.2-0.4-0.20.20.00.3
Soleus weight1.13.37.7-1.5-1.51.0-0.42.81.9-1.92.2-2.0
Bone: stiffness1.72.65.4-0.6-0.8-1.81.6-2.3-2.12.1-0.41.4
Tibialis anterior weight4.013.634.35.95.83.4-4.20.62.2-2.2-3.80.9
Time to tail flick, vehicle, before self-admin1.91.93.4-1.1-0.8-1.61.6-1.8-1.81.8-0.30.4
Time to tail flick, vehicle, after self-admin0.50.51.40.80.7-0.40.1-1.2-0.70.7-0.31.0
Time to tail flick, test, before self-admin2.01.92.8-1.3-1.5-1.71.6-1.4-1.61.6-0.21.1
Time to tail flick, test, after self-admin0.10.10.60.20.40.3-0.2-0.00.1-0.10.1-0.8
Delta time to tail flick, vehicle, before/after SA0.30.31.21.10.80.2-0.6-0.10.2-0.20.60.4
Delta time to tail flick, test, before/after SA3.63.35.51.92.42.1-2.11.51.8-1.8-0.4-1.4
Tibia length0.72.03.01.61.51.7-1.71.31.6-1.6-0.4-0.7
Ambulatory time before self-admin0.20.20.4-0.4-0.6-0.40.5-0.6-0.60.60.3-0.4
Ambulatory time after self-admin1.21.32.5-1.3-1.6-1.11.3-0.9-1.11.1-1.00.7
Bone: tissue strength0.50.52.0-0.6-0.7-0.50.6-0.3-0.40.41.4-0.3
Total heroin consumption0.80.93.71.61.90.2-0.7-0.8-0.20.2-0.80.4
Bone: trabecular number2.13.25.5-1.2-1.4-2.12.0-2.3-2.32.3-0.21.0
Bone: trabecular spacing0.70.91.50.50.71.1-1.01.21.2-1.20.7-0.6
Bone: trabecular thickness1.82.13.4-1.7-1.8-1.71.8-1.3-1.51.60.40.3
Bone: trabecular tissue density1.31.85.3-1.1-1.00.9-0.52.31.6-1.61.0-1.3
Water consumed over 24 hours0.20.30.90.20.2-0.50.4-0.9-0.70.70.20.2
Number of responses in last shaping day0.20.20.7-0.3-0.30.1-0.10.60.4-0.4-0.00.8