Hub : Genes

Unc80

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Unc80 0.06 0.04 2.9e-04 0 0.02 0.01 0.01 1.1e-01 1.8e-03 3.8e-02 4.1e-02
2 IC gene expression Unc80 0.17 0.08 2.2e-04 0.02 0.07 0.06 0.04 5.8e-02 8.9e-04 1.2e-03 1.3e-02
3 BLA intron excision ratio chr9_75612851_75615087 0.08 0.04 2.2e-03 0.06 0.04 0.02 0.05 5.3e-04 3.1e-03 2.6e-02 1.7e-03
4 Adipose gene expression Unc80 0.29 0.1 0.0e+00 0.18 0.18 0.18 0.18 9.4e-20 9.9e-20 3.0e-19 1.4e-19
5 pVTA mRNA stability Unc80 0.05 0.03 5.3e-05 0.08 0.06 0.06 0.07 2.8e-07 8.0e-06 7.3e-06 2.3e-06
6 Liver mRNA stability Unc80 0.04 0.02 7.3e-04 0.02 -0 0.01 0.01 2.1e-03 4.2e-01 1.9e-02 1.4e-02
7 pVTA intron excision ratio chr9_75626124_75633223 0.05 0.03 2.8e-04 0.05 0.03 0.04 0.03 1.3e-04 2.8e-03 7.4e-04 1.1e-03
8 IC mRNA stability Unc80 0.15 0.09 3.2e-03 0 0 0 0 2.5e-01 2.6e-01 2.7e-01 2.9e-01
9 Brain gene expression Unc80 0.05 0.03 2.7e-04 0.04 0.04 0.03 0.04 9.0e-05 2.2e-04 3.7e-04 3.1e-04
10 Liver gene expression Unc80 0.19 0.07 0.0e+00 0.11 0.12 0.11 0.11 2.9e-12 1.2e-13 5.4e-12 6.8e-12
11 PL mRNA stability Unc80 0.06 0.04 4.0e-03 0 0.02 0.01 0 1.1e-01 3.3e-03 2.4e-02 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.10.4-0.3-0.60.0-0.40.40.1-0.5-0.30.3-0.10.4
Area under the delay curve0.20.20.60.3-0.1-0.50.6-0.40.60.4-0.7-0.3-0.30.2
BMI with tail3.813.025.25.04.7-5.04.8-3.1-3.33.50.31.0-1.63.5
BMI without tail1.03.17.62.12.2-2.82.4-0.9-1.01.31.11.8-0.01.9
Body weight0.31.44.4-0.5-0.9-0.50.31.21.4-1.51.02.11.50.9
Weight adjusted by age0.10.10.50.50.1-0.10.4-0.2-0.20.2-0.2-0.50.10.7
Bone surface0.40.71.6-0.5-0.90.1-0.41.00.9-0.70.41.21.01.0
Bone volume0.50.92.5-1.3-1.60.8-1.21.10.6-1.30.00.60.6-0.1
Breakpoint value in progressive ratio session0.60.72.2-0.50.11.4-0.90.00.30.1-0.9-0.8-0.8-1.5
Number of licking bursts0.30.52.00.5-0.1-0.80.9-0.1-0.4-0.81.00.60.41.4
Context. condit. distance diff. score0.40.51.40.1-0.5-0.70.3-1.0-1.1-0.7-0.1-0.4-1.20.5
Locomotion velocity, session 10.80.92.6-0.90.21.0-1.21.00.20.30.90.81.2-1.6
Locomotion distance, session 10.20.21.3-0.10.2-0.40.1-0.2-1.20.5-0.50.1-0.1-0.7
Locomotion velocity, session 21.51.76.0-0.0-0.1-0.50.41.40.6-0.51.82.42.01.6
Locomotion distance, session 20.50.71.80.61.2-0.90.7-0.0-1.30.90.81.00.5-0.2
Locomotion velocity, session 31.61.85.20.70.6-0.50.4-1.8-2.31.1-1.3-1.7-2.1-0.1
Locomotion distance, session 31.21.33.7-1.9-1.61.5-1.70.70.4-0.7-0.1-0.40.6-1.2
Stereotopy head waving bouts, day 34.65.412.23.23.5-1.81.8-2.4-2.42.8-1.9-1.7-2.10.5
Stereotopy head waving duration, day 34.85.812.53.53.5-2.11.9-2.7-2.62.2-1.7-1.6-2.50.8
Locomotion velocity, session 71.82.05.2-1.8-2.2-0.1-0.21.1-0.1-1.32.12.30.80.4
Locomotion distance, session 73.03.89.5-2.4-2.20.4-0.92.21.1-1.72.63.12.3-0.1
Stereotopy head waving bouts, day 70.10.10.70.3-0.1-0.40.4-0.1-0.0-0.1-0.20.1-0.30.8
Stereotopy head waving duration, day 71.61.95.01.30.3-1.51.7-1.8-1.7-0.1-0.9-0.7-2.21.2
Locomotion velocity, session 80.50.62.90.50.2-0.70.8-0.0-1.70.50.90.9-0.21.0
Locomotion distance, session 80.20.31.50.0-0.1-0.70.4-0.3-1.2-0.00.70.7-0.20.4
Degree of sensitization distance1.11.14.80.30.2-1.11.00.70.3-0.41.62.20.80.9
Degree of sensitization stereotypy0.40.51.7-0.2-0.9-0.70.80.00.4-0.80.80.7-0.01.3
Conditioned locomotion0.30.31.6-0.2-0.20.5-0.41.30.5-0.40.10.70.80.2
Cocaine response after cond. corrected0.40.51.4-0.6-0.11.0-1.20.61.00.30.1-0.30.6-0.8
Cocaine response after cond. not corrected1.11.22.4-1.5-1.31.4-1.51.21.6-0.8-0.00.10.8-0.7
Cocaine response before conditioning1.31.54.9-1.3-2.20.3-0.11.21.2-2.20.11.20.50.8
Saline control response0.60.82.41.31.1-1.00.9-0.00.10.7-0.40.50.71.6
Bone: connectivity density0.61.04.90.7-0.1-1.51.10.10.3-0.20.61.20.42.2
Bone: cortical apparent density1.92.64.91.91.8-2.01.8-0.2-0.11.42.21.70.62.0
Bone: cortical area1.52.36.5-1.1-0.90.6-0.42.30.5-1.02.32.62.10.2
Bone: cortical porosity4.14.410.3-2.5-2.23.2-3.12.21.7-2.2-0.7-0.61.0-1.9
Bone: cortical porosity4.65.011.9-2.6-2.13.5-3.32.51.8-2.2-0.6-0.51.2-2.0
Bone: cortical thickness1.62.69.4-0.8-0.70.10.02.30.5-0.63.12.62.30.7
Bone: cortical thickness0.40.51.4-0.8-0.60.6-0.51.21.0-0.10.51.00.5-0.2
Bone: cortical tissue density2.02.74.72.01.8-2.11.9-0.4-0.21.42.21.60.52.1
Condit. Reinf. active minus inactive responses0.70.81.8-0.10.31.0-1.21.21.40.5-0.80.21.30.2
Condit. Reinf. active-inactive response ratio0.30.31.10.40.80.4-0.60.2-0.01.0-0.5-0.20.3-0.0
Condit. Reinf. active responses1.11.33.8-0.7-0.51.2-1.41.62.0-0.0-0.80.31.80.2
Condit. Reinf. inactive responses0.81.03.3-0.9-0.80.9-0.71.11.8-0.6-1.00.01.4-0.3
Incentive salience index mean0.70.92.6-0.4-0.31.0-1.11.41.60.0-0.40.21.50.6
Condit. Reinf. lever presses0.40.51.2-0.6-0.90.6-0.41.11.1-0.30.3-0.00.90.6
Condit. Reinf. active minus inactive responses4.25.49.6-3.1-3.03.1-2.82.92.4-1.9-0.50.11.9-1.3
Condit. Reinf. active-inactive response ratio3.84.48.8-3.0-2.92.8-2.62.11.8-1.8-0.8-0.51.1-1.8
Condit. Reinf. active responses2.83.96.5-2.4-2.42.6-2.32.52.5-1.7-0.40.21.8-0.6
Condit. Reinf. inactive responses0.30.41.3-0.1-0.30.5-0.40.71.2-0.80.00.50.80.6
Condit. Reinf. lever presses0.50.83.2-0.8-0.71.2-1.10.60.40.1-1.8-0.60.1-0.6
Condit. Reinf. lever reinforcers received3.24.47.8-2.7-2.82.7-2.42.62.5-2.0-0.40.31.7-0.8
Conditioned reinforcement - actives1.01.73.71.91.7-1.11.6-1.3-1.20.9-1.3-1.3-1.00.5
Conditioned reinforcement - inactives0.40.62.2-0.1-0.21.5-0.70.60.5-0.6-0.9-0.60.9-0.9
Conditioned locomotion4.86.211.12.61.8-3.03.3-3.1-2.52.3-1.9-2.2-2.80.7
Patch foraging indifference point 0 sec0.61.12.51.31.1-0.61.00.70.90.3-0.31.21.51.6
Patch foraging indifference point AUC0.30.41.1-1.0-0.60.1-0.50.60.6-0.50.80.50.5-0.9
Delay disc. indifference point, 0s delay0.50.51.60.60.4-1.21.3-0.8-0.20.50.20.2-0.80.6
Delay disc. indifference point, 16s delay0.40.41.50.0-0.80.10.3-0.50.40.4-1.2-1.0-0.70.4
Delay disc. indifference point, 2s delay1.01.22.90.60.1-1.41.5-1.3-1.21.0-0.8-0.4-1.70.3
Delay disc. indifference point, 24s delay0.50.62.11.00.6-0.60.60.31.3-0.00.10.40.71.5
Delay disc. indifference point, 4s delay0.40.41.50.60.7-1.20.8-1.0-0.30.5-0.3-0.1-0.40.1
Delay disc. indifference point, 8s delay0.40.53.2-0.4-0.70.10.20.51.8-0.60.00.50.60.3
Indifference point function ln k0.71.22.71.71.1-0.91.3-1.0-1.31.0-0.6-0.2-1.21.2
Indifference point function log k0.71.22.71.71.1-0.91.3-1.0-1.31.0-0.6-0.2-1.21.2
Patch foraging total patch changes 0 sec0.50.91.91.41.2-0.50.90.40.70.4-0.50.81.11.4
Patch foraging total patch changes 12 sec0.00.00.10.10.4-0.10.1-0.10.00.1-0.30.00.1-0.3
Patch foraging total patch changes 18 sec0.30.51.80.81.3-0.70.70.20.10.50.40.60.70.6
Patch foraging total patch changes 24 sec0.20.32.10.10.4-0.00.1-0.00.60.6-1.4-0.60.1-0.3
Patch foraging total patch changes 6 sec0.60.92.21.21.0-1.41.2-0.10.30.2-0.41.00.61.5
Patch foraging time to switch 0 sec0.20.31.0-0.6-0.10.8-1.0-0.2-0.50.1-0.3-0.5-0.1-1.0
Patch foraging water rate 0 sec0.20.40.9-0.1-0.5-0.80.90.50.7-0.7-0.30.80.50.9
Patch foraging water rate 12 sec0.30.60.90.80.7-0.80.7-0.8-0.70.9-0.9-0.7-0.90.4
Patch foraging water rate 18 sec0.30.53.3-0.1-0.10.7-0.6-0.3-0.10.1-1.8-1.0-0.6-0.4
Patch foraging water rate 24 sec0.10.10.4-0.5-0.20.1-0.00.50.1-0.20.10.60.2-0.2
Patch foraging water rate 6 sec1.21.74.31.71.4-2.11.9-0.8-0.81.1-0.10.2-0.51.9
Seeking ratio, delayed vs. immediate footshock0.81.03.4-0.0-0.30.7-0.6-1.1-1.1-0.1-1.6-1.8-1.0-0.6
Distance traveled before self-admin0.40.61.4-1.0-1.11.2-1.00.5-0.1-0.7-0.40.0-0.4-0.8
Distance traveled after self-admin0.40.51.9-1.1-1.4-0.6-0.1-0.1-1.1-0.4-0.00.5-0.3-0.2
Extensor digitorum longus weight1.35.010.43.02.7-3.12.9-0.7-0.71.21.72.11.03.2
Bone: elastic displacement0.50.62.11.01.0-0.30.50.0-0.61.40.50.4-0.41.0
Bone: elastic work0.40.51.6-0.3-0.40.6-0.51.30.2-0.21.01.00.70.7
Bone: endosteal estimation0.81.83.3-1.7-1.61.8-1.70.70.7-1.5-1.6-0.30.0-1.6
Bone: endosteal perimeter0.20.51.4-0.5-0.51.1-1.00.1-0.2-0.5-1.2-0.4-0.4-0.9
Epididymis fat weight0.82.67.70.0-0.7-0.81.21.51.5-1.32.52.81.42.0
Delta time in closed arm before/after self-admin0.90.83.31.10.5-0.61.00.11.1-0.30.51.00.61.8
Delta time in open arm before/after self-admin2.62.66.4-0.8-0.72.1-1.3-0.7-1.30.5-2.0-2.5-1.4-2.5
Diff in mean of infusions in LGA sessions3.03.69.13.02.7-1.31.8-2.0-0.91.9-1.6-1.5-1.61.5
Delay discount exponential model param0.20.30.9-0.40.00.5-0.60.5-0.5-0.51.00.40.4-0.2
Extinction: sum of active levers before priming0.80.91.60.90.7-0.30.7-1.2-1.30.8-1.3-1.1-1.3-0.1
Active lever presses in extinction session 60.10.10.2-0.4-0.40.3-0.30.2-0.3-0.1-0.4-0.20.0-0.5
Bone: final force1.21.94.4-2.0-2.11.5-1.51.50.7-1.8-0.10.90.6-1.0
Bone: final moment0.91.53.3-1.8-1.81.3-1.41.20.6-1.5-0.40.80.4-0.9
Food consumed during 24 hour testing period0.91.34.2-1.0-0.61.0-1.0-0.7-0.9-0.6-0.6-1.6-1.5-2.0
Glucose0.40.62.31.10.4-1.01.2-0.5-0.2-0.2-0.30.50.01.5
Heart weight0.60.92.80.10.71.7-1.21.11.21.2-0.20.01.0-0.2
Delay discount hyperbolic model param0.20.20.7-0.30.00.5-0.70.5-0.5-0.40.80.30.4-0.2
Intermittent access intake day 1-15 change1.73.56.62.32.2-0.41.0-2.1-1.62.0-2.6-2.4-2.0-0.1
Intermittent access intake escalation1.73.67.52.32.1-0.30.9-2.1-1.62.0-2.7-2.6-1.9-0.1
Intermittent access intake escalation 24.04.67.92.52.3-0.71.1-2.5-2.12.3-2.8-2.7-2.60.1
Intermitt. access day 1 inactive lever presses0.10.41.2-0.10.80.4-0.70.30.70.40.30.40.8-1.1
Intermitt. access day 15 inactive lever presses0.51.14.20.60.20.9-0.4-1.1-0.60.3-2.0-1.9-1.1-0.5
Intermitt. access escalation Index0.30.40.70.90.7-0.60.1-0.8-0.30.8-0.6-0.4-0.80.6
Intermittent access day 1 total infusions0.40.71.5-1.2-1.20.3-0.5-0.6-0.3-0.6-1.1-1.0-0.3-1.1
Intermittent access day 15 total infusions1.31.95.61.30.7-0.81.0-1.9-1.11.1-2.4-2.1-1.3-0.0
Intermittent access terminal intake (last 3 days)2.83.78.31.91.4-1.21.4-2.6-1.91.5-2.9-2.7-2.0-0.1
Intermittent access total infusions1.41.75.60.2-0.2-0.70.7-1.8-1.30.4-2.4-2.0-1.3-0.7
Intermittent access day 1 locomotion0.20.31.3-0.8-1.2-0.40.4-0.30.30.2-0.4-0.2-0.1-0.2
Intermittent access day 15 total locomotion1.22.13.41.00.5-1.71.4-1.8-1.41.8-1.8-1.4-1.90.1
Intermittent access total locomotion2.63.15.41.51.0-2.12.3-2.3-1.41.9-1.9-1.7-1.90.4
Intermittent access standard deviation1.12.36.30.50.70.3-0.0-1.8-1.11.7-2.5-2.5-1.7-1.5
Left kidney weight0.31.33.21.41.1-1.31.40.1-0.20.41.71.40.01.8
Right kidney weight0.73.210.40.60.5-1.31.21.41.1-1.13.03.21.62.2
Cocaine induced anxiety0.10.20.90.00.40.3-0.2-0.5-0.40.1-0.1-0.4-0.3-0.9
Post-drug Anxiety0.50.52.10.70.8-0.50.6-0.9-1.50.30.2-0.3-0.8-0.2
Baseline Anxiety0.50.61.61.10.6-1.11.1-0.4-0.80.50.20.3-0.41.3
Tail length3.714.424.7-5.0-4.73.9-3.94.14.5-5.01.11.83.2-2.2
Length with tail4.017.328.0-5.2-5.14.6-4.44.85.1-5.31.01.73.4-2.2
Length without tail1.65.213.8-2.7-3.41.9-1.62.42.8-3.70.51.11.8-0.1
Times rat made contact with spout0.70.83.2-1.0-0.31.3-1.40.20.0-0.50.6-0.4-0.3-1.8
Lifetime Intake1.11.44.40.2-0.2-0.90.8-1.7-1.30.2-2.1-1.7-1.2-0.6
Liver weight, left1.01.65.5-1.4-0.72.1-2.30.70.6-0.5-0.2-0.6-0.1-2.0
Liver weight, right0.50.92.10.51.2-0.1-0.4-1.0-0.91.4-1.0-1.1-0.6-1.1
Locomotor activity0.20.31.21.10.8-0.70.6-0.20.10.4-0.5-0.30.10.4
Locomotor testing distance0.10.20.60.70.6-0.10.20.00.8-0.0-0.2-0.50.30.0
Locomotor testing rearing0.10.10.40.50.30.00.30.10.60.1-0.6-0.10.10.2
Locomotion in novel chamber1.21.52.81.61.2-0.51.0-1.2-1.21.2-1.1-1.2-1.71.0
Locomotion in novel chamber post-restriction0.30.41.10.2-0.2-0.30.70.70.6-0.20.31.00.81.1
Fecal boli incidents, locomotor time 10.60.92.4-1.1-1.31.3-0.80.60.5-1.6-0.7-0.2-0.1-0.8
Change in fecal boli incidents, locomotor task0.30.31.70.60.70.0-0.1-0.2-0.31.30.7-0.2-0.20.0
Time >=10cm from walls, locomotor time 11.21.32.6-1.3-0.21.5-1.61.21.30.60.20.21.1-1.6
Bouts of movement, locomotor time 10.70.82.1-0.10.71.0-1.01.10.9-0.11.00.51.5-0.9
Total resting periods, locomotor time 10.80.92.7-0.20.90.8-1.01.10.8-0.11.10.71.7-1.1
Rest time, locomotor task time 10.50.71.7-0.20.41.2-1.31.20.4-0.40.40.11.3-0.8
Distance moved, locomotor task time 10.71.02.8-1.3-1.7-0.60.50.61.2-0.70.91.40.60.6
Vertical activity count, locomotor time 10.20.40.8-0.4-0.9-0.90.6-0.20.50.10.70.7-0.30.9
Time >=10cm from walls, locomotor time 20.40.62.8-0.50.21.0-0.9-0.1-0.00.7-0.2-0.9-0.1-1.7
Bouts of movement, locomotor time 20.50.81.41.21.1-0.51.00.10.80.60.90.90.71.2
Total resting periods, locomotor time 20.30.51.10.91.0-0.10.50.20.90.50.70.70.70.6
Rest time, locomotor task time 20.60.82.70.10.81.0-1.21.20.9-0.4-0.00.21.6-0.7
Distance moved, locomotor task time 20.30.30.7-0.7-0.8-0.80.7-0.10.30.00.70.80.00.2
Vertical activity count, locomotor time 21.21.64.01.30.9-2.01.6-1.5-1.31.30.00.0-1.51.1
Light reinforcement 10.92.35.32.22.3-1.61.4-1.9-1.31.3-0.5-0.6-1.31.0
Light reinforcement 20.40.71.9-0.7-0.70.8-0.9-0.9-0.3-0.1-0.9-1.4-1.0-0.7
Bone: marrow area0.81.73.0-1.6-1.61.7-1.60.80.7-1.5-1.5-0.10.2-1.5
Bone: maximum diameter0.61.13.2-0.7-0.41.2-0.91.80.2-0.60.61.61.3-0.4
Bone: maximum force0.71.22.9-1.7-1.71.1-1.20.6-0.1-1.5-0.50.0-0.1-1.3
Bone: maximum moment0.40.71.7-1.3-1.30.8-0.90.3-0.2-1.1-0.8-0.2-0.3-1.1
Mean time between licks in bursts0.30.81.91.31.4-0.91.0-0.1-0.60.61.00.9-0.00.9
Mean num. licks in bursts0.60.94.1-0.90.11.2-1.40.40.50.5-0.7-0.5-0.3-2.0
Cd content in liver1.51.74.00.60.6-0.40.4-1.8-1.80.9-1.3-2.0-1.9-0.9
Co content in liver0.10.10.4-0.4-0.40.2-0.10.1-0.60.00.40.3-0.3-0.6
Cu content in liver1.61.97.6-0.5-1.1-0.40.51.51.4-1.41.12.81.51.5
Fe content in liver0.40.51.8-0.30.11.1-1.30.61.0-0.2-0.3-0.60.8-0.4
K content in liver0.80.82.50.2-0.2-0.90.90.70.5-0.80.91.60.91.3
Mg content in liver0.70.82.20.2-0.2-0.80.80.60.7-0.80.81.30.91.5
Mn content in liver1.82.06.42.42.5-1.31.3-0.6-1.01.50.60.5-0.31.5
Na content in liver0.30.30.9-0.6-0.90.3-0.40.80.6-0.60.10.60.20.6
Rb content in liver0.20.30.6-0.1-0.3-0.50.50.7-0.10.60.60.60.50.7
Se content in liver0.20.30.70.1-0.0-0.30.20.60.8-0.40.70.60.80.7
Sr content in liver0.90.72.80.71.71.1-1.10.60.60.5-0.1-0.40.9-0.7
Zn content in liver0.40.41.1-0.1-0.4-0.50.70.20.8-0.60.81.10.60.6
Bone: minimum diameter1.22.24.0-1.9-1.81.7-1.72.00.9-1.90.80.81.5-0.7
Time in familiar zone, hab. session 13.73.67.21.61.1-1.41.7-2.7-1.92.1-2.3-2.2-2.40.4
Time in novel zone, hab. session 13.73.78.1-1.9-1.02.6-2.82.61.6-1.71.61.31.9-1.4
Total zone transitions, hab. session 11.41.94.0-1.4-1.40.6-0.71.91.7-1.50.31.72.00.4
Total locomotion distance, hab. session 10.91.22.3-1.2-1.21.3-1.31.31.1-1.0-0.70.51.5-0.2
Locomotion velocity, hab. session 11.01.53.4-1.2-1.31.1-1.11.61.4-1.4-0.20.91.80.1
Time in familiar zone, hab. session 21.21.23.1-0.10.1-0.80.2-1.5-1.70.4-1.6-1.3-1.5-1.1
Time in novel zone, hab. session 20.80.92.00.70.70.7-0.21.01.3-0.21.40.91.21.1
Total zone transitions, hab. session 20.10.10.30.00.3-0.1-0.20.1-0.40.0-0.60.10.0-0.4
Total locomotion distance, hab. session 20.10.20.50.40.6-0.1-0.1-0.1-0.70.2-0.7-0.30.2-0.1
Locomotion velocity, hab. session 20.10.20.60.30.5-0.1-0.0-0.1-0.80.2-0.8-0.20.3-0.1
Novel to familiar place preference ratio1.21.33.3-1.1-1.11.4-0.91.31.8-1.60.40.61.2-0.5
Novelty place preference1.01.12.5-0.9-0.91.5-0.91.21.6-1.40.40.41.0-0.5
Time in novel zone, NPP test1.01.12.5-0.9-0.91.6-1.11.11.6-1.50.30.30.8-0.6
Total zone transitions, NPP test0.10.10.4-0.10.2-0.2-0.30.2-0.1-0.1-0.60.30.3-0.3
Total locomotion distance, NPP test0.10.20.7-0.10.30.3-0.40.3-0.20.2-0.9-0.00.8-0.5
Locomotion velocity, NPP test0.10.20.70.10.5-0.1-0.10.1-0.40.5-0.80.00.8-0.3
Intraocular pressure0.91.42.71.11.5-1.31.3-1.4-1.71.40.0-0.4-1.2-0.3
Delta distance traveled before/after self-admin0.60.62.90.3-0.2-1.70.9-0.4-0.90.30.30.5-0.01.1
Delta ambulatory time before/after self-admin0.50.62.1-0.4-0.6-1.40.50.1-0.5-0.11.01.10.40.8
Parametrial fat weight1.22.74.6-1.9-1.50.6-0.71.82.0-2.02.11.91.9-0.5
Pavlov. Cond. lever latency1.92.44.11.01.8-0.30.0-1.8-1.91.8-1.3-1.8-2.0-1.7
Pavlov. Cond. magazine entry latency1.82.36.2-2.1-2.51.2-1.21.52.1-1.6-0.20.71.3-0.0
Pavlov. Cond. change in total contacts1.71.94.0-1.2-2.0-0.10.41.31.7-1.40.81.81.51.5
Pavlov. Cond. index score1.72.15.0-1.6-2.20.7-0.61.62.1-1.70.51.31.61.0
Pavlov. Cond. latency score1.62.14.7-1.5-2.20.7-0.61.62.0-1.70.51.31.61.0
Pavlov. Cond. lever contacts1.21.42.9-0.6-1.30.20.21.31.7-1.00.81.31.61.7
Pavlov. Cond. magazine entry number1.21.64.01.62.0-0.60.6-1.3-2.01.10.3-0.9-1.4-0.4
Pavlov. Cond. intertrial magazine entries0.40.52.41.31.6-0.10.20.4-0.30.8-0.30.60.50.7
Pavlov. Cond. lever-magazine prob. diff.1.41.74.6-1.5-2.10.7-0.41.41.8-1.40.51.21.40.9
Pavlov. Cond. response bias1.92.35.9-1.6-2.00.8-0.61.82.4-1.50.11.22.10.8
Pavlov. Cond. lever latency0.60.81.90.80.7-1.41.3-0.60.1-0.61.30.60.30.9
Pavlov. Cond. magazine entry latency1.31.56.6-0.10.30.7-0.6-0.7-0.91.4-2.6-1.5-1.3-1.4
Pavlov. Cond. change in total contacts0.50.92.2-1.0-0.71.5-1.30.70.30.2-1.5-0.40.1-1.1
Pavlov. Cond. index score1.11.54.7-0.7-0.21.6-1.40.2-0.51.1-2.2-1.4-0.7-1.6
Pavlov. Cond. latency score1.01.45.0-0.8-0.41.5-1.40.2-0.40.9-2.2-1.2-0.6-1.5
Pavlov. Cond. lever contacts0.81.23.0-1.0-0.71.7-1.60.80.00.5-1.6-0.9-0.1-1.2
Pavlov. Cond. magazine entry number1.21.56.60.1-0.4-0.90.80.40.7-1.52.61.51.01.3
Pavlov. Cond. intertrial magazine entries1.82.76.60.3-0.6-1.41.40.81.8-2.01.92.11.62.6
Pavlov. Cond. lever-magazine prob. diff.1.31.75.9-0.50.01.5-1.3-0.0-0.61.4-2.4-1.6-0.8-1.7
Pavlov. Cond. response bias1.01.32.9-0.8-0.31.7-1.60.4-0.31.1-1.7-1.3-0.5-1.6
Time in closed arm before self-admin1.41.85.4-2.3-1.61.1-2.20.8-0.3-0.7-0.0-0.3-0.3-2.0
Time in closed arm after self-admin1.21.22.5-1.2-1.10.3-0.81.31.6-1.11.21.50.80.2
Time in open arm before self-admin2.72.98.22.72.2-1.82.2-0.20.11.00.71.21.02.9
Time in open arm after self-admin1.41.54.40.20.51.2-0.6-1.0-1.60.7-2.1-1.8-0.6-1.6
Bone: periosteal estimation1.02.24.2-1.8-1.71.6-1.42.10.8-1.70.41.51.4-0.9
Bone: periosteal perimeter0.30.51.5-0.6-0.31.2-1.10.9-0.2-0.4-0.20.10.4-1.0
Bone: post-yield work1.01.53.2-0.3-0.2-0.30.1-1.5-1.7-0.0-1.7-1.6-1.8-1.7
Progressive ratio test 1 active lever presses0.20.31.20.1-0.2-0.20.4-0.8-0.1-0.1-0.7-1.1-0.1-0.2
Progressive ratio test 1 breakpoint0.20.21.1-0.1-0.4-0.10.3-0.70.0-0.4-0.7-1.10.0-0.2
Progressive ratio test 1 inactive lever presses0.20.20.60.60.5-0.70.8-0.40.40.1-0.5-0.30.30.2
Progressive ratio test 2 active lever presses0.40.52.20.80.5-0.10.3-0.8-0.30.5-1.5-1.2-0.4-0.1
Progressive ratio test 2 breakpoint0.40.52.10.70.40.10.2-0.7-0.20.5-1.4-1.2-0.3-0.2
Progressive ratio test 2 inactive lever presses0.91.43.11.21.2-0.80.7-1.5-1.20.9-1.8-1.5-1.2-0.4
Incentive Sensitization - Responses0.20.31.40.60.70.0-0.1-0.3-0.30.8-1.2-0.6-0.4-0.3
Incentive Sensitization - Breakpoint0.20.31.20.50.6-0.0-0.1-0.3-0.30.7-1.1-0.5-0.4-0.3
Sum of active levers in priming session hrs 5-61.21.12.1-1.0-1.30.9-0.51.31.4-1.11.11.00.80.4
Progressive ratio0.50.72.5-0.5-0.20.5-0.50.71.60.30.71.21.40.3
Food seeking constrained by brief footshock1.72.14.72.01.4-2.02.2-1.1-0.91.3-0.60.1-1.11.9
Seeking ratio, punishment vs. effort0.81.23.00.90.3-1.21.3-1.2-1.30.0-1.1-0.9-1.70.6
Retroperitoneal fat weight0.52.27.8-0.4-0.8-1.31.41.10.9-1.42.82.51.01.1
Reaction time number correct0.81.64.42.12.1-0.70.9-0.9-0.91.7-0.1-0.6-0.61.5
Reaction time mean minus median0.10.21.0-0.20.40.2-0.5-0.1-0.10.1-0.3-0.6-0.3-1.0
Reaction time mean minus median AUC0.10.31.0-0.20.40.5-0.60.0-0.20.3-0.7-0.7-0.5-1.0
Reaction time num false alarms1.42.05.11.91.4-2.32.2-0.8-1.30.20.80.2-0.61.6
Reaction time num false alarms AUC1.01.64.01.81.5-2.02.0-0.5-1.10.00.70.3-0.21.5
Reaction time trials correct on left0.81.64.42.12.1-0.70.9-0.9-0.91.7-0.1-0.6-0.61.5
Reaction time trials on left0.81.54.32.12.0-0.70.9-0.9-0.81.6-0.1-0.6-0.61.5
Reaction time mean2.23.46.7-2.5-1.92.6-2.51.91.8-1.10.7-0.00.9-2.2
Reaction time mean AUC2.13.36.4-2.5-2.02.3-2.31.91.9-1.31.00.21.1-1.9
Median of all reaction times3.75.29.6-3.1-2.63.1-2.92.62.5-1.51.10.41.6-2.1
Reaction time omissions0.20.30.8-0.6-0.20.3-0.80.60.6-0.90.60.20.1-0.4
Reaction time false alarm rate0.40.61.80.30.0-1.31.20.1-0.4-1.20.80.80.20.5
Reaction time premature initiation rate0.20.31.0-0.00.11.0-0.50.1-0.20.8-0.9-0.4-0.4-0.3
Reaction time premature initiations0.50.93.11.21.30.50.1-0.5-0.81.8-1.1-0.9-0.90.3
Std. dev. reaction times0.71.23.7-1.6-0.81.2-1.60.90.9-0.90.0-0.20.1-1.9
Reaction time trials completed0.81.54.32.12.0-0.70.9-0.9-0.81.6-0.1-0.6-0.61.5
Reaction time trials AUC0.71.43.82.01.9-0.60.8-0.8-0.81.6-0.2-0.7-0.61.3
Run reversals in cocaine runway, females0.20.20.9-0.6-0.10.00.00.30.7-0.1-0.30.70.9-0.4
Run reversals in cocaine runway, males0.40.40.9-0.8-1.00.6-0.40.50.3-0.90.60.50.3-0.1
Latency to leave start box in cocaine runway1.61.84.11.61.3-1.51.90.30.30.71.61.31.12.0
Latency to leave start box in cocaine runway, F1.21.43.31.20.9-1.61.70.20.20.41.51.20.71.8
Latency to leave start box in cocaine runway, M0.60.51.81.21.1-0.30.9-0.2-0.11.30.2-0.10.30.8
Std. dev. time between licks in bursts2.02.76.32.52.4-2.22.2-1.2-0.81.30.40.60.02.1
Total sessions with >9 infusions0.20.20.90.2-0.1-0.10.4-0.30.20.1-1.0-0.90.1-0.2
Short access day 1 total inactive lever presses0.50.72.50.4-0.2-1.61.4-0.7-1.20.5-0.6-0.1-0.70.3
Short access day 10 total inactive lever presses0.20.40.9-0.5-0.10.5-0.80.90.4-0.00.80.70.7-0.7
Short access day 1 total infusions0.60.81.61.10.3-1.01.3-0.9-0.90.4-1.0-0.7-0.90.8
Short access day 10 total infusions0.40.51.2-0.2-0.6-0.70.7-0.9-0.8-0.3-1.1-0.9-0.4-0.3
Short access total infusions0.60.81.50.60.2-1.21.2-1.2-0.80.4-1.2-1.0-0.80.1
Short access day 1 locomotion0.20.20.70.0-0.50.30.00.50.8-0.1-0.0-0.20.80.5
Short access day 10 total locomotion0.10.31.00.00.1-0.90.7-0.3-0.21.00.1-0.3-0.5-0.2
Short access total locomotion0.30.41.60.50.1-1.31.2-0.50.00.7-0.2-0.3-0.20.3
One hour access (0.3 mA shock)0.50.61.8-0.2-0.2-0.40.5-1.0-0.41.0-1.3-1.1-0.9-0.6
Compulsive drug intake0.30.31.2-0.6-0.0-0.0-0.10.40.4-0.01.11.10.8-0.3
One hour access (shock baseline)0.60.93.8-0.2-0.5-0.10.2-1.0-0.6-0.2-2.0-1.6-1.2-0.7
Social response proportion0.20.20.60.1-0.20.00.10.40.5-0.50.70.70.30.6
Social responses0.20.30.7-0.4-0.30.7-0.60.90.7-0.40.20.70.40.0
Social time0.20.30.90.50.50.9-0.30.10.50.3-0.9-0.7-0.40.1
Soleus weight0.20.72.91.21.7-0.50.2-1.0-0.90.1-0.9-0.8-0.1-0.1
Bone: stiffness0.61.02.3-1.4-1.50.8-1.0-0.1-0.5-1.4-1.0-0.6-0.6-1.3
Tibialis anterior weight0.30.91.81.21.0-1.31.3-1.1-0.91.0-0.40.4-0.30.9
Time to tail flick, vehicle, before self-admin0.50.51.0-0.60.00.5-0.81.00.9-0.41.00.80.8-0.6
Time to tail flick, vehicle, after self-admin0.50.62.1-0.9-0.11.1-1.40.4-0.1-0.90.3-0.30.5-1.3
Time to tail flick, test, before self-admin1.71.83.8-1.9-1.30.8-1.21.31.2-1.31.51.61.1-0.7
Time to tail flick, test, after self-admin4.54.78.12.72.3-2.02.5-2.8-1.82.5-1.5-1.8-2.50.5
Delta time to tail flick, vehicle, before/after SA1.21.14.10.20.20.00.1-1.4-2.00.6-1.0-1.5-1.4-0.6
Delta time to tail flick, test, before/after SA7.37.513.63.72.9-2.02.6-3.1-2.63.3-2.5-2.7-2.90.9
Tibia length1.54.18.2-2.9-2.62.2-2.22.31.6-2.20.51.21.9-1.5
Ambulatory time before self-admin0.30.51.0-0.7-0.80.9-0.6-0.0-0.5-0.3-0.9-0.4-1.0-0.9
Ambulatory time after self-admin0.40.51.4-0.7-1.0-1.10.4-0.1-1.2-0.30.30.9-0.30.5
Bone: tissue strength0.30.30.7-0.2-0.7-0.30.3-0.6-0.8-0.80.2-0.4-0.60.2
Total heroin consumption0.50.52.3-0.8-0.61.5-0.80.50.4-0.6-0.1-0.2-0.3-1.1
Bone: trabecular number0.20.31.10.2-0.5-0.80.4-0.4-0.1-0.3-0.6-0.2-0.41.0
Bone: trabecular spacing1.31.73.4-1.6-1.21.3-0.91.80.8-0.71.71.41.5-1.0
Bone: trabecular thickness0.60.82.2-0.5-0.50.4-0.7-1.0-0.7-0.5-1.3-1.5-0.9-1.0
Bone: trabecular tissue density0.60.84.3-0.80.01.1-1.00.60.70.90.3-0.10.5-2.1
Water consumed over 24 hours0.10.20.60.20.50.1-0.2-0.5-0.80.10.4-0.2-0.5-0.4
Number of responses in last shaping day1.82.03.6-1.1-1.51.0-0.81.91.7-1.81.11.41.70.9