Hub : Genes

Unc13a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr16_18379955_18380405 0.34 0.15 6.2e-06 0.04 0.05 0.06 0.04 1.3e-05 2.2e-06 2.7e-07 8.3e-05
2 PL intron excision ratio chr16_18375992_18377274 0.27 0.16 6.5e-06 0.05 0.05 0.06 0.04 5.4e-06 4.6e-06 8.4e-07 1.4e-05
3 NAcc gene expression Unc13a 0.19 0.08 1.3e-15 0.1 0.11 0.1 0.11 1.6e-15 8.7e-17 1.2e-15 5.1e-16
4 NAcc isoform ratio XM_063275697.1 0.02 0.01 4.6e-03 0.02 0.01 0.01 0.01 1.4e-03 1.1e-02 8.6e-03 6.7e-03
5 BLA isoform ratio XM_063275702.1 0.14 0.08 6.6e-06 0.09 0.05 0.05 0.08 1.2e-05 1.0e-03 1.1e-03 5.5e-05
6 Brain isoform ratio XM_063275702.1 0.05 0.04 3.3e-03 0.03 0.03 0.02 0.02 8.5e-04 1.1e-03 2.6e-03 2.3e-03
7 PL isoform ratio XM_063275697.1 0.06 0.04 1.6e-05 0.04 0.04 0.04 0.04 2.4e-05 1.7e-05 1.6e-05 2.5e-05
8 PL isoform ratio XM_063275702.1 0.07 0.05 5.3e-06 0.06 0.05 0.05 0.05 1.2e-07 3.2e-06 6.8e-06 1.4e-06
9 Brain intron excision ratio chr16_18379955_18380405 0.19 0.12 1.7e-11 0.13 0.11 0.12 0.12 8.8e-12 1.2e-10 2.0e-11 4.6e-11
10 PL gene expression Unc13a 0.03 0.02 7.3e-03 0.02 0.01 0.02 0.02 1.1e-03 1.0e-02 6.6e-03 5.9e-03
11 Brain intron excision ratio chr16_18375992_18377274 0.22 0.14 8.8e-12 0.14 0.13 0.12 0.14 1.1e-12 3.4e-12 1.3e-11 6.3e-13
12 Adipose gene expression Unc13a 0.04 0.04 5.7e-03 0.01 0.01 0.01 0.01 3.4e-02 3.7e-02 3.2e-02 3.7e-02
13 BLA gene expression Unc13a 0.23 0.12 5.8e-10 0.14 0.15 0.18 0.17 1.3e-07 3.6e-08 4.3e-10 1.5e-09
14 IC gene expression Unc13a 0.27 0.12 1.8e-08 0.15 0.18 0.17 0.16 6.0e-07 5.4e-08 1.4e-07 3.8e-07
15 BLA isoform ratio XM_063275697.1 0.11 0.07 3.1e-05 0.03 0.06 0.06 0.01 1.7e-02 5.2e-04 2.4e-04 5.0e-02
16 Brain gene expression Unc13a 0.22 0.11 1.3e-14 0.14 0.14 0.14 0.15 1.3e-12 3.5e-13 2.2e-13 1.2e-13
17 BLA intron excision ratio chr16_18375992_18377274 0.06 0.05 6.9e-03 0 0.01 0.01 0.01 2.3e-01 1.4e-01 1.3e-01 1.5e-01
18 pVTA gene expression Unc13a 0.04 0.03 1.5e-03 0.05 0.04 0.04 0.04 1.1e-04 2.6e-04 3.7e-04 1.5e-04
19 Brain mRNA stability Unc13a 0.11 0.07 6.4e-09 0.08 0.07 0.09 0.04 4.0e-08 5.8e-07 1.2e-08 1.2e-04
20 OFC mRNA stability Unc13a 0.2 0.19 4.4e-03 0.04 0.1 0.12 0.09 3.9e-02 2.0e-03 1.0e-03 4.2e-03
21 IC intron excision ratio chr16_18409379_18409940 0.09 0.06 4.2e-03 0.02 0.03 0.03 0.03 6.6e-02 1.6e-02 2.5e-02 2.5e-02
22 PL mRNA stability Unc13a 0.06 0.04 6.0e-06 0.05 0.05 0.04 0.04 6.3e-06 4.8e-06 1.5e-05 2.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.93.26.12.1-1.82.3-1.81.81.8-2.42.52.51.8-2.2-1.61.92.1-1.91.3-1.1-0.41.31.9-0.40.9
Area under the delay curve1.01.22.8-1.51.7-1.11.1-1.1-1.11.1-1.1-1.2-0.91.11.0-1.2-1.11.2-0.11.2-0.0-1.0-1.30.6-0.7
BMI with tail1.96.613.13.6-3.43.4-3.13.13.1-3.03.02.93.0-2.8-2.52.12.5-2.12.0-2.1-1.91.31.60.40.2
BMI without tail1.85.414.93.9-2.83.3-2.82.82.8-2.62.62.52.7-2.3-1.61.21.9-1.22.8-1.0-2.7-0.00.71.6-0.9
Body weight4.820.940.36.3-4.96.1-5.55.45.4-5.55.45.45.1-5.1-4.23.74.6-3.84.3-3.3-4.21.82.81.30.1
Weight adjusted by age1.21.87.92.8-1.91.9-1.31.31.3-1.51.51.51.4-1.3-1.00.71.1-0.61.7-0.6-1.60.10.20.9-0.5
Bone surface1.73.14.71.6-2.01.9-1.81.81.8-2.12.22.21.8-2.0-1.92.12.1-2.00.5-1.60.11.71.9-0.91.4
Bone volume2.03.66.02.2-2.22.4-2.02.02.0-2.42.52.42.2-2.2-1.91.92.2-1.91.2-1.4-0.61.31.6-0.30.9
Breakpoint value in progressive ratio session0.70.92.1-0.7-0.40.2-0.80.70.7-0.80.80.81.0-1.0-1.01.51.3-1.4-0.3-1.10.21.00.9-1.11.3
Number of licking bursts0.10.20.4-0.70.5-0.50.3-0.3-0.30.5-0.5-0.6-0.40.50.4-0.4-0.40.4-0.20.30.2-0.2-0.30.0-0.1
Context. condit. distance diff. score0.00.10.20.10.20.3-0.30.30.3-0.20.30.30.0-0.30.10.20.3-0.30.40.0-0.2-0.10.20.10.0
Locomotion velocity, session 14.04.37.30.8-2.21.4-2.12.12.1-1.81.81.82.0-2.0-2.52.72.2-2.7-1.1-2.70.72.52.3-2.22.4
Locomotion distance, session 12.32.96.6-0.1-1.30.6-1.11.11.1-1.11.11.11.2-1.3-2.12.11.5-2.0-1.8-2.31.82.62.0-2.52.5
Locomotion velocity, session 21.72.03.21.5-1.61.8-1.71.71.7-1.71.61.61.8-1.6-1.41.31.5-1.41.0-1.2-1.20.70.90.10.3
Locomotion distance, session 21.72.46.5-0.2-1.10.5-0.60.60.6-0.90.90.90.9-1.0-1.91.61.1-1.6-2.0-2.12.12.51.9-2.52.4
Locomotion velocity, session 30.10.20.4-0.30.00.1-0.10.10.1-0.30.30.30.2-0.3-0.50.50.4-0.4-0.3-0.30.60.60.6-0.60.7
Locomotion distance, session 30.70.71.8-0.1-0.40.4-0.60.60.6-0.60.60.60.6-0.7-1.11.00.7-1.0-0.8-1.01.01.41.3-1.21.2
Stereotopy head waving bouts, day 30.20.20.7-0.10.10.2-0.20.20.2-0.40.40.40.0-0.4-0.30.60.5-0.6-0.2-0.20.50.60.9-0.70.7
Stereotopy head waving duration, day 30.10.10.2-0.00.10.2-0.20.20.2-0.40.40.40.3-0.3-0.30.40.5-0.40.2-0.0-0.00.30.3-0.20.3
Locomotion velocity, session 70.50.51.7-0.90.4-1.00.6-0.6-0.60.9-1.0-1.0-0.50.90.2-0.5-0.80.5-1.3-0.11.00.2-0.6-0.70.3
Locomotion distance, session 71.21.62.7-1.51.1-1.71.4-1.4-1.41.6-1.6-1.6-1.51.41.0-1.1-1.41.0-1.50.61.3-0.2-0.7-0.50.0
Stereotopy head waving bouts, day 72.42.63.71.3-1.51.8-1.81.81.8-1.91.91.91.8-1.9-1.81.91.9-1.90.5-1.5-0.31.41.7-0.81.2
Stereotopy head waving duration, day 72.02.33.71.3-1.21.9-1.81.81.8-1.91.91.91.8-1.9-1.61.71.8-1.71.1-1.1-0.80.91.4-0.20.7
Locomotion velocity, session 81.41.73.60.3-1.10.7-1.11.11.1-1.01.01.01.0-1.1-1.61.51.2-1.6-1.2-1.91.11.81.5-1.81.9
Locomotion distance, session 81.62.34.20.5-1.21.0-1.31.31.3-1.31.31.31.2-1.4-1.81.81.5-1.8-1.1-2.01.22.11.8-1.92.0
Degree of sensitization distance1.81.92.8-1.01.2-1.51.4-1.4-1.41.7-1.7-1.7-1.61.61.7-1.6-1.61.5-0.51.30.3-1.2-1.40.5-0.9
Degree of sensitization stereotypy2.72.94.01.5-1.81.9-2.02.02.0-2.02.02.02.0-2.0-1.91.91.9-1.90.6-1.7-0.51.41.6-0.61.0
Conditioned locomotion0.10.20.7-0.80.8-0.50.4-0.4-0.40.5-0.5-0.4-0.40.40.2-0.3-0.40.3-0.20.30.2-0.2-0.20.1-0.2
Cocaine response after cond. corrected3.44.07.0-1.12.5-1.62.2-2.2-2.21.9-1.8-1.7-2.21.92.5-2.3-2.02.40.92.6-0.5-2.4-2.01.8-2.0
Cocaine response after cond. not corrected2.42.84.5-1.12.0-1.62.0-2.0-2.01.7-1.6-1.6-2.01.82.1-1.9-1.72.00.22.10.0-1.8-1.61.1-1.3
Cocaine response before conditioning1.11.33.20.2-1.60.2-0.70.70.7-0.60.60.50.8-0.6-1.31.21.0-1.3-1.4-1.61.11.71.1-1.81.8
Saline control response1.41.82.91.1-1.41.2-1.31.31.3-1.41.41.41.3-1.4-1.51.61.4-1.6-0.4-1.50.61.61.7-1.21.4
Bone: connectivity density1.01.62.81.1-1.11.4-1.31.31.3-1.61.71.71.2-1.5-1.31.51.6-1.50.7-1.0-0.11.01.4-0.50.9
Bone: cortical apparent density0.00.10.4-0.30.6-0.10.3-0.3-0.30.1-0.0-0.0-0.20.10.0-0.1-0.00.1-0.2-0.00.40.10.1-0.30.2
Bone: cortical area5.58.518.54.3-3.73.9-3.63.63.6-3.33.23.33.5-3.1-2.32.12.7-2.12.8-1.9-2.90.61.41.2-0.4
Bone: cortical porosity1.11.23.20.5-1.40.6-1.11.11.1-0.80.70.71.2-0.8-1.51.10.9-1.2-0.9-1.80.61.40.8-1.21.2
Bone: cortical porosity1.31.43.40.6-1.40.7-1.21.21.2-1.00.90.81.3-0.9-1.61.31.1-1.3-0.8-1.90.61.50.9-1.31.3
Bone: cortical thickness5.89.718.44.3-3.84.1-3.93.93.9-3.63.63.63.7-3.5-2.72.63.0-2.62.4-2.4-2.21.32.20.50.3
Bone: cortical thickness2.83.36.32.5-1.72.5-2.32.32.3-2.22.22.22.1-2.1-1.51.51.8-1.51.6-1.2-1.40.61.30.40.1
Bone: cortical tissue density0.10.10.6-0.50.8-0.30.4-0.4-0.40.2-0.2-0.2-0.40.20.1-0.1-0.10.2-0.30.00.50.10.0-0.30.2
Condit. Reinf. active minus inactive responses2.12.43.51.5-1.71.7-1.81.81.8-1.71.71.71.9-1.7-1.81.71.7-1.60.4-1.5-0.51.31.3-0.61.0
Condit. Reinf. active-inactive response ratio0.30.40.60.7-0.60.8-0.70.70.7-0.70.70.70.8-0.7-0.60.50.6-0.50.5-0.4-0.70.20.30.10.1
Condit. Reinf. active responses2.63.34.81.8-1.92.0-2.12.12.1-2.12.02.02.2-2.0-2.12.02.1-2.00.5-1.9-0.61.41.5-0.71.2
Condit. Reinf. inactive responses0.50.61.00.8-0.80.8-1.01.01.0-0.80.80.81.0-0.8-0.80.70.8-0.70.3-0.9-0.40.40.4-0.20.3
Incentive salience index mean5.66.99.52.3-2.92.7-2.92.92.9-2.92.92.93.0-3.0-3.13.02.9-3.00.4-2.8-0.52.42.5-1.31.9
Condit. Reinf. lever presses8.812.317.12.8-4.03.5-3.93.93.9-3.83.83.84.0-3.9-4.14.13.9-4.10.3-3.8-0.43.43.5-2.02.7
Condit. Reinf. active minus inactive responses0.50.61.30.5-1.00.5-0.70.70.7-0.70.70.70.6-0.8-0.80.90.7-0.9-0.6-0.90.61.21.1-0.91.0
Condit. Reinf. active-inactive response ratio0.50.61.41.1-1.21.0-0.90.90.9-0.80.80.80.9-0.8-0.60.60.7-0.60.5-0.6-0.60.40.50.10.0
Condit. Reinf. active responses0.30.41.9-0.2-0.3-0.30.0-0.0-0.00.0-0.0-0.1-0.0-0.1-0.50.50.1-0.5-1.4-0.61.21.10.8-1.31.1
Condit. Reinf. inactive responses1.31.73.4-1.71.4-1.81.5-1.5-1.51.5-1.5-1.6-1.51.40.8-0.8-1.20.8-1.80.61.70.0-0.4-0.90.5
Condit. Reinf. lever presses0.00.00.10.3-0.30.1-0.10.10.1-0.00.0-0.00.0-0.00.20.0-0.0-0.00.20.3-0.2-0.20.10.2-0.2
Condit. Reinf. lever reinforcers received0.10.10.5-0.1-0.1-0.30.2-0.2-0.20.2-0.2-0.3-0.20.20.00.0-0.2-0.1-0.7-0.10.60.40.3-0.50.3
Conditioned reinforcement - actives0.30.62.11.1-0.30.8-0.30.30.3-0.30.30.30.2-0.20.2-0.5-0.20.61.40.3-1.4-0.9-0.71.5-1.4
Conditioned reinforcement - inactives1.82.710.92.5-1.01.8-1.11.11.1-1.11.11.01.2-0.80.1-0.40.40.43.30.4-3.3-1.6-1.12.8-2.3
Conditioned locomotion0.91.14.00.60.40.30.3-0.3-0.30.3-0.3-0.3-0.50.41.0-1.3-0.91.41.61.2-1.6-1.5-1.32.0-2.0
Patch foraging indifference point 0 sec1.01.85.01.6-0.71.7-1.51.51.5-1.61.61.61.4-1.3-0.80.91.5-1.12.1-0.5-2.2-0.20.21.0-0.4
Patch foraging indifference point AUC0.40.52.8-1.71.7-0.70.8-0.9-0.90.4-0.3-0.5-0.60.50.5-0.4-0.30.40.21.00.2-0.3-0.40.2-0.1
Delay disc. indifference point, 0s delay1.11.23.2-1.81.3-1.31.2-1.2-1.21.2-1.2-1.2-1.11.10.6-0.7-1.10.8-1.50.61.50.1-0.4-0.70.3
Delay disc. indifference point, 16s delay4.44.89.4-2.93.1-2.32.3-2.3-2.32.4-2.3-2.4-2.52.42.4-2.4-2.42.3-0.72.30.6-1.8-1.90.8-1.3
Delay disc. indifference point, 2s delay0.20.20.9-0.90.4-0.4-0.00.10.10.2-0.3-0.00.1-0.1-0.40.40.3-0.4-0.8-0.50.60.50.1-1.01.0
Delay disc. indifference point, 24s delay0.60.71.4-0.10.6-0.50.7-0.7-0.70.7-0.7-0.8-0.80.91.0-1.2-1.01.00.40.9-0.5-1.1-0.91.0-1.2
Delay disc. indifference point, 4s delay0.30.40.70.6-0.40.6-0.60.70.7-0.60.50.60.7-0.7-0.80.70.7-0.6-0.0-0.80.00.70.4-0.40.6
Delay disc. indifference point, 8s delay2.02.34.6-1.72.1-1.31.5-1.4-1.41.3-1.3-1.5-1.21.51.6-1.7-1.41.70.62.0-0.7-1.9-1.91.4-1.5
Indifference point function ln k0.40.85.32.3-2.10.9-1.01.01.0-0.30.20.40.7-0.5-0.10.10.0-0.20.4-0.7-0.9-0.3-0.00.6-0.6
Indifference point function log k0.40.85.32.3-2.10.9-1.01.01.0-0.30.20.40.7-0.5-0.10.10.0-0.20.4-0.7-0.9-0.3-0.00.6-0.6
Patch foraging total patch changes 0 sec1.32.57.52.2-1.02.0-1.71.61.6-1.81.81.71.6-1.5-0.70.81.5-1.02.6-0.4-2.7-0.60.11.5-0.8
Patch foraging total patch changes 12 sec0.30.42.2-0.10.70.6-0.0-0.0-0.0-0.60.70.60.4-0.20.2-0.20.40.01.50.8-1.0-0.6-0.31.0-0.6
Patch foraging total patch changes 18 sec0.30.54.2-1.92.0-0.80.6-0.7-0.70.4-0.3-0.5-0.70.50.3-0.2-0.20.20.10.80.1-0.1-0.20.0-0.0
Patch foraging total patch changes 24 sec0.20.30.6-0.50.70.4-0.40.30.3-0.70.70.70.5-0.6-0.40.50.8-0.70.80.0-0.60.10.40.10.1
Patch foraging total patch changes 6 sec0.71.03.30.90.01.3-1.01.01.0-1.31.31.30.9-1.1-0.40.71.2-0.81.8-0.1-1.7-0.20.40.8-0.3
Patch foraging time to switch 0 sec0.30.52.6-1.00.3-0.60.3-0.2-0.20.3-0.2-0.2-0.60.1-0.30.3-0.1-0.3-1.4-0.41.61.10.8-1.31.1
Patch foraging water rate 0 sec0.81.76.02.4-1.91.8-1.41.31.3-1.41.31.31.8-1.3-0.90.81.1-0.71.3-0.8-1.5-0.10.20.7-0.3
Patch foraging water rate 12 sec0.40.84.72.2-2.01.1-1.00.90.9-0.60.60.60.9-0.6-0.40.30.3-0.10.4-0.9-0.70.00.20.4-0.3
Patch foraging water rate 18 sec0.60.93.61.3-1.90.5-0.80.80.8-0.60.50.61.0-0.7-1.01.00.7-1.0-1.0-1.40.51.00.6-1.11.1
Patch foraging water rate 24 sec2.63.712.63.3-3.52.1-2.01.91.9-1.91.81.72.3-1.7-2.01.71.6-1.6-0.1-2.5-0.31.41.3-0.81.0
Patch foraging water rate 6 sec0.50.73.61.9-1.11.0-0.60.50.5-0.40.30.31.1-0.4-0.3-0.2-0.00.41.0-0.2-1.4-0.8-0.61.2-1.1
Seeking ratio, delayed vs. immediate footshock0.40.53.01.6-1.70.5-0.20.20.20.00.00.2-0.0-0.1-0.5-0.0-0.4-0.1-1.1-0.81.01.00.9-0.50.2
Distance traveled before self-admin0.81.13.31.8-1.51.3-1.01.01.0-1.21.21.21.3-1.1-0.90.91.1-0.81.0-0.8-1.00.20.50.20.1
Distance traveled after self-admin2.12.65.72.4-2.41.9-1.61.71.7-1.81.81.81.8-1.8-1.51.61.7-1.81.0-1.4-0.90.91.1-0.10.5
Extensor digitorum longus weight0.72.85.22.2-1.92.3-1.91.91.9-2.02.12.11.8-2.0-1.51.41.6-1.41.2-1.0-1.01.01.50.20.3
Bone: elastic displacement1.01.22.40.9-1.30.8-1.01.01.0-0.90.90.91.1-0.9-1.51.21.0-1.1-0.7-1.50.61.41.0-1.21.3
Bone: elastic work1.72.35.42.3-1.92.1-1.81.81.8-1.71.61.72.1-1.5-1.40.91.4-0.91.5-1.1-1.50.30.40.6-0.2
Bone: endosteal estimation0.71.53.2-0.80.8-1.11.2-1.2-1.21.2-1.2-1.3-0.91.41.3-1.5-1.31.50.31.3-0.5-1.4-1.81.1-1.3
Bone: endosteal perimeter0.30.52.40.7-0.70.2-0.20.20.20.1-0.2-0.20.40.30.4-0.6-0.30.51.10.4-1.5-1.1-1.11.4-1.3
Epididymis fat weight0.82.65.12.3-2.02.1-2.02.02.0-1.81.81.72.1-1.7-1.61.21.6-1.31.2-1.5-1.50.70.60.30.2
Delta time in closed arm before/after self-admin1.41.33.5-1.61.9-1.11.0-1.0-1.01.0-1.0-1.0-0.91.11.4-1.2-0.81.00.51.5-0.5-1.5-1.40.9-0.9
Delta time in open arm before/after self-admin0.20.21.0-0.50.0-0.40.3-0.2-0.20.2-0.1-0.1-0.4-0.0-0.00.30.0-0.2-0.8-0.31.00.60.6-0.90.7
Diff in mean of infusions in LGA sessions0.30.41.80.8-0.40.6-0.50.50.5-0.60.50.50.7-0.4-0.10.20.6-0.21.2-0.2-1.3-0.6-0.50.7-0.4
Delay discount exponential model param0.60.71.61.0-1.30.7-0.80.70.7-0.80.80.80.7-0.8-0.80.90.8-0.9-0.2-1.00.31.01.1-0.60.7
Extinction: sum of active levers before priming1.31.53.40.1-1.00.5-0.80.80.8-0.90.90.90.9-1.1-1.31.61.3-1.5-1.0-1.50.91.71.4-1.71.8
Active lever presses in extinction session 60.00.00.2-0.1-0.4-0.20.2-0.2-0.20.2-0.2-0.20.10.1-0.2-0.1-0.1-0.0-0.4-0.10.40.2-0.1-0.20.2
Bone: final force3.65.812.73.6-2.73.3-2.72.72.7-2.72.62.53.0-2.3-1.41.11.9-1.03.5-0.8-3.5-0.40.22.2-1.3
Bone: final moment2.94.611.93.3-2.42.9-2.42.42.4-2.22.12.12.6-1.9-1.00.61.5-0.63.4-0.4-3.4-0.8-0.22.3-1.6
Food consumed during 24 hour testing period1.41.94.20.3-1.30.8-1.21.21.2-1.21.21.11.1-1.3-1.71.71.4-1.7-0.9-1.51.12.11.8-1.71.8
Glucose0.60.92.41.2-0.91.1-1.31.31.3-1.00.90.91.3-0.9-0.70.60.9-0.61.3-0.6-1.5-0.30.00.7-0.3
Heart weight3.04.79.33.1-2.92.6-2.52.52.5-2.52.52.62.4-2.5-1.82.02.3-2.01.2-1.8-1.31.21.8-0.10.7
Delay discount hyperbolic model param0.30.31.20.8-1.10.5-0.50.40.4-0.50.50.50.3-0.4-0.50.50.4-0.5-0.2-0.60.30.70.8-0.40.4
Intermittent access intake day 1-15 change0.20.50.91.0-0.90.8-0.80.80.8-0.80.80.70.7-0.7-0.70.80.7-0.70.2-0.7-0.20.50.6-0.20.4
Intermittent access intake escalation0.20.40.60.7-0.80.6-0.70.70.7-0.70.70.60.6-0.6-0.70.80.7-0.70.1-0.80.10.70.7-0.50.6
Intermittent access intake escalation 20.30.41.21.1-1.00.8-0.70.70.7-0.70.60.60.6-0.5-0.50.40.5-0.50.6-0.3-0.40.20.20.2-0.1
Intermitt. access day 1 inactive lever presses0.10.21.31.2-0.60.6-0.40.40.4-0.30.30.30.3-0.2-0.1-0.10.10.10.6-0.1-0.6-0.2-0.00.5-0.5
Intermitt. access day 15 inactive lever presses0.00.10.50.6-0.70.00.1-0.1-0.10.1-0.1-0.20.10.2-0.0-0.2-0.40.5-0.2-0.10.20.1-0.10.1-0.3
Intermitt. access escalation Index0.40.61.1-1.10.7-0.91.0-0.9-0.90.9-0.9-0.8-0.90.80.5-0.7-0.90.5-0.90.70.8-0.1-0.2-0.2-0.1
Intermittent access day 1 total infusions1.32.14.4-1.42.0-0.81.0-1.0-1.01.1-1.1-1.1-1.01.21.7-1.7-1.21.91.31.5-1.3-2.1-2.01.8-1.9
Intermittent access day 15 total infusions0.20.30.6-0.40.7-0.10.2-0.2-0.20.3-0.3-0.3-0.40.40.6-0.6-0.40.80.60.4-0.5-0.7-0.70.7-0.7
Intermittent access terminal intake (last 3 days)0.50.61.4-1.11.2-0.60.6-0.6-0.60.6-0.6-0.7-0.70.71.1-0.8-0.71.00.50.8-0.4-1.0-1.00.8-0.9
Intermittent access total infusions1.11.43.4-0.81.4-0.40.6-0.6-0.60.7-0.6-0.6-0.80.81.5-1.3-0.81.51.51.2-1.4-1.8-1.61.7-1.6
Intermittent access day 1 locomotion0.91.23.4-0.51.3-0.10.2-0.3-0.30.4-0.4-0.4-0.50.51.3-1.1-0.51.11.81.0-1.8-1.8-1.51.8-1.6
Intermittent access day 15 total locomotion0.10.21.0-1.00.8-0.40.2-0.2-0.20.3-0.2-0.2-0.40.20.6-0.2-0.10.20.50.4-0.4-0.6-0.40.4-0.3
Intermittent access total locomotion0.70.93.6-0.41.20.1-0.00.00.00.1-0.1-0.0-0.40.21.2-0.6-0.00.71.90.8-1.8-1.7-1.21.5-1.2
Intermittent access standard deviation0.10.20.70.9-0.40.30.1-0.1-0.10.1-0.1-0.1-0.10.20.4-0.5-0.50.60.60.3-0.4-0.5-0.40.8-0.9
Left kidney weight0.83.96.02.1-1.72.4-2.42.42.4-2.42.42.32.1-2.3-2.12.02.3-2.01.3-1.7-1.31.31.5-0.10.7
Right kidney weight1.46.39.93.1-2.53.1-3.13.13.1-2.92.92.92.8-2.9-2.62.32.7-2.22.1-2.0-2.21.31.60.40.4
Cocaine induced anxiety0.30.52.21.0-0.30.6-0.50.50.5-0.50.50.50.5-0.50.20.10.6-0.21.50.2-1.5-0.8-0.41.0-0.6
Post-drug Anxiety0.00.00.20.5-0.40.3-0.10.10.1-0.10.10.20.2-0.1-0.0-0.0-0.10.20.10.1-0.1-0.0-0.10.2-0.2
Baseline Anxiety0.70.84.1-0.90.0-0.70.6-0.6-0.60.6-0.6-0.6-0.50.5-0.3-0.2-0.80.5-2.0-0.22.01.10.4-1.30.8
Tail length0.72.86.92.6-1.52.3-2.12.02.0-1.91.91.82.0-1.7-1.51.21.6-1.21.8-0.9-1.90.20.80.8-0.2
Length with tail1.98.213.23.4-2.23.6-3.43.43.4-3.53.53.43.1-3.3-2.82.73.3-2.72.8-2.1-2.91.21.90.70.4
Length without tail1.85.88.92.6-2.03.0-2.72.82.8-2.93.03.02.4-2.9-2.42.42.8-2.52.2-2.0-2.11.42.00.30.6
Times rat made contact with spout0.10.10.6-0.4-0.2-0.30.0-0.0-0.00.1-0.1-0.1-0.00.0-0.30.30.0-0.2-0.6-0.20.80.70.5-0.60.6
Lifetime Intake0.91.13.7-0.11.00.20.2-0.2-0.20.2-0.2-0.2-0.40.41.1-1.1-0.61.31.81.0-1.8-1.7-1.41.9-1.8
Liver weight, left1.22.03.40.8-1.31.0-1.41.41.4-1.21.21.11.2-1.4-1.61.71.3-1.6-0.9-1.80.91.81.7-1.61.8
Liver weight, right1.11.93.51.9-1.61.8-1.81.71.7-1.51.61.51.4-1.5-1.41.11.3-1.11.3-1.1-1.40.71.00.4-0.0
Locomotor activity4.36.811.92.9-3.42.3-2.82.82.8-2.52.52.52.6-2.7-3.03.02.7-3.0-0.5-3.10.22.72.6-1.92.4
Locomotor testing distance1.32.44.91.8-2.21.2-1.61.51.5-1.31.31.31.3-1.5-1.61.81.4-1.8-0.8-1.70.81.81.8-1.51.7
Locomotor testing rearing1.32.65.30.4-1.40.7-1.41.31.3-1.21.21.31.3-1.5-1.82.21.8-2.3-1.0-1.91.12.11.9-2.12.3
Locomotion in novel chamber0.60.81.51.2-1.00.9-0.90.90.9-0.91.01.10.8-1.1-1.01.01.0-0.90.2-0.7-0.20.81.0-0.40.7
Locomotion in novel chamber post-restriction2.13.46.51.0-1.71.4-1.91.91.9-1.81.81.91.9-2.0-2.12.42.2-2.5-0.5-2.10.42.11.9-1.72.1
Fecal boli incidents, locomotor time 10.60.91.6-1.00.8-1.11.1-1.1-1.11.2-1.3-1.1-0.61.10.7-1.0-1.21.0-0.40.80.5-0.7-1.00.3-0.6
Change in fecal boli incidents, locomotor task0.40.41.1-1.00.7-0.90.8-0.8-0.80.7-0.7-0.7-0.70.70.6-0.6-0.60.7-0.60.40.4-0.3-0.5-0.1-0.1
Time >=10cm from walls, locomotor time 10.70.72.8-1.31.7-0.80.9-0.9-0.90.8-0.9-0.8-0.50.90.7-0.8-0.70.70.10.7-0.1-0.8-1.00.4-0.5
Bouts of movement, locomotor time 10.20.31.3-0.70.0-0.40.2-0.3-0.30.00.0-0.1-0.20.0-0.20.50.1-0.2-0.90.11.10.70.7-0.90.7
Total resting periods, locomotor time 10.40.52.2-1.20.5-0.80.6-0.6-0.60.4-0.3-0.3-0.60.30.10.2-0.20.0-1.30.21.50.70.6-1.00.8
Rest time, locomotor task time 10.50.61.5-0.20.7-0.50.9-1.0-1.00.8-0.8-0.8-0.70.90.6-1.1-1.21.2-0.21.00.2-0.6-0.70.6-0.9
Distance moved, locomotor task time 10.00.10.4-0.60.4-0.40.1-0.1-0.10.3-0.3-0.3-0.40.20.5-0.10.0-0.00.10.20.0-0.3-0.2-0.10.1
Vertical activity count, locomotor time 10.41.01.51.1-1.21.0-1.21.11.1-1.11.11.00.8-1.1-1.01.21.2-1.2-0.0-1.20.01.01.0-0.71.0
Time >=10cm from walls, locomotor time 20.60.92.1-0.40.7-0.81.0-1.1-1.11.2-1.2-1.2-0.91.10.7-1.2-1.41.3-0.70.50.7-0.4-0.80.2-0.6
Bouts of movement, locomotor time 20.50.81.90.1-0.50.5-0.70.70.7-0.91.00.90.4-0.9-0.71.31.1-1.2-0.3-0.80.61.01.4-1.01.2
Total resting periods, locomotor time 20.30.51.4-0.1-0.20.3-0.50.60.6-0.80.90.70.2-0.8-0.51.11.0-1.1-0.2-0.50.50.71.2-0.81.0
Rest time, locomotor task time 20.10.20.70.4-0.30.4-0.40.40.4-0.40.40.50.4-0.4-0.20.20.4-0.20.60.1-0.8-0.10.10.4-0.3
Distance moved, locomotor task time 20.60.81.5-0.20.4-0.80.9-1.0-1.01.0-1.0-1.2-1.01.10.9-1.1-1.21.1-0.31.00.3-0.7-0.90.5-0.7
Vertical activity count, locomotor time 20.20.21.71.3-0.70.7-0.40.40.4-0.50.40.20.6-0.3-0.60.10.2-0.00.2-0.30.10.2-0.10.10.0
Light reinforcement 10.41.01.9-1.31.4-1.20.9-0.9-0.91.1-1.2-1.1-0.71.20.9-1.0-0.90.70.11.0-0.4-1.1-1.20.7-0.8
Light reinforcement 23.35.010.8-2.03.3-2.02.1-2.1-2.12.2-2.1-2.1-2.42.22.7-2.5-2.12.31.02.7-1.0-2.7-2.32.0-2.2
Bone: marrow area0.61.42.9-0.80.8-1.11.2-1.2-1.21.2-1.2-1.2-0.91.41.3-1.4-1.21.40.21.2-0.4-1.4-1.71.0-1.1
Bone: maximum diameter1.32.46.32.5-2.02.1-1.81.81.8-1.61.51.51.9-1.3-0.80.61.1-0.62.1-0.7-2.3-0.5-0.11.4-0.9
Bone: maximum force5.39.419.44.4-4.04.1-3.63.63.6-3.63.53.44.0-3.2-2.62.12.8-2.13.2-1.9-3.20.71.11.4-0.4
Bone: maximum moment3.96.815.53.9-3.53.6-3.13.13.1-3.02.82.83.4-2.6-2.01.62.3-1.52.9-1.5-3.00.20.71.5-0.7
Mean time between licks in bursts0.81.95.42.3-2.21.8-1.71.71.7-1.31.21.21.7-1.1-0.70.50.9-0.61.6-0.6-2.1-0.4-0.01.2-0.9
Mean num. licks in bursts0.20.30.60.5-0.80.4-0.40.40.4-0.60.60.60.5-0.6-0.60.60.5-0.6-0.1-0.50.30.60.6-0.40.5
Cd content in liver0.60.72.60.8-0.00.40.0-0.1-0.10.0-0.1-0.00.10.20.6-0.9-0.50.91.30.7-1.4-1.3-1.01.6-1.5
Co content in liver0.00.10.20.1-0.20.1-0.20.10.1-0.20.30.30.1-0.2-0.30.30.4-0.40.2-0.2-0.30.40.2-0.10.2
Cu content in liver2.12.56.00.1-1.30.4-1.11.11.1-0.90.90.90.9-1.2-1.82.01.5-2.0-1.6-2.21.62.31.8-2.42.4
Fe content in liver0.60.81.8-1.20.8-1.11.3-1.3-1.30.9-0.8-0.9-1.20.90.8-0.7-0.80.7-0.80.61.0-0.1-0.3-0.30.1
K content in liver1.81.72.9-1.71.5-1.71.6-1.6-1.61.5-1.5-1.5-1.51.51.0-1.1-1.41.1-1.40.61.2-0.3-1.0-0.50.0
Mg content in liver0.10.10.4-0.50.6-0.40.3-0.3-0.30.4-0.4-0.4-0.30.40.0-0.2-0.30.2-0.2-0.00.1-0.0-0.4-0.10.0
Mn content in liver0.20.30.80.1-0.40.4-0.80.80.8-0.40.30.30.8-0.4-0.90.50.5-0.5-0.2-0.9-0.20.50.1-0.30.3
Na content in liver0.90.94.2-0.7-0.0-0.60.2-0.2-0.20.2-0.2-0.3-0.20.1-0.60.60.1-0.6-2.1-0.92.01.40.9-1.91.6
Rb content in liver1.51.84.80.11.1-0.20.8-0.8-0.80.6-0.6-0.5-0.80.81.5-1.5-1.01.51.81.7-1.8-2.0-1.72.2-2.1
Se content in liver0.40.51.10.2-0.60.3-0.40.50.5-0.50.50.40.5-0.6-0.70.90.7-0.9-0.6-1.10.60.90.7-1.01.1
Sr content in liver0.30.30.6-0.70.7-0.80.7-0.7-0.70.6-0.7-0.6-0.70.60.5-0.4-0.50.4-0.40.30.4-0.2-0.4-0.20.1
Zn content in liver0.10.20.7-0.0-0.10.0-0.20.20.2-0.20.20.20.3-0.3-0.60.50.4-0.5-0.3-0.80.30.50.2-0.60.6
Bone: minimum diameter1.12.15.82.4-2.01.9-1.81.81.8-1.51.51.51.7-1.4-0.90.81.1-0.81.6-0.7-1.7-0.00.41.0-0.5
Time in familiar zone, hab. session 10.00.00.1-0.20.30.1-0.10.10.1-0.20.20.20.1-0.1-0.10.10.2-0.20.3-0.1-0.3-0.0-0.00.10.0
Time in novel zone, hab. session 10.00.00.10.3-0.20.0-0.10.10.10.0-0.1-0.10.20.1-0.0-0.1-0.10.10.10.0-0.1-0.1-0.20.1-0.1
Total zone transitions, hab. session 10.40.61.8-0.3-0.30.1-0.30.30.3-0.40.40.40.7-0.4-1.00.80.6-0.8-1.1-1.11.01.10.6-1.41.3
Total locomotion distance, hab. session 11.11.65.1-0.7-0.50.0-0.50.50.5-0.50.50.50.9-0.6-1.61.41.0-1.3-1.9-1.81.62.01.1-2.32.2
Locomotion velocity, hab. session 11.01.44.8-0.7-0.6-0.1-0.40.40.4-0.40.30.30.7-0.5-1.41.20.8-1.2-1.9-1.71.61.91.0-2.22.1
Time in familiar zone, hab. session 20.00.00.10.10.00.0-0.00.00.00.0-0.0-0.0-0.30.00.4-0.1-0.10.10.20.2-0.2-0.3-0.10.2-0.2
Time in novel zone, hab. session 20.20.20.3-0.30.5-0.40.5-0.5-0.50.4-0.4-0.4-0.10.40.2-0.5-0.50.50.10.5-0.1-0.4-0.60.3-0.4
Total zone transitions, hab. session 20.10.10.4-0.3-0.2-0.1-0.10.10.1-0.0-0.0-0.00.2-0.1-0.40.30.1-0.3-0.7-0.60.50.50.2-0.60.5
Total locomotion distance, hab. session 21.41.93.80.6-1.40.9-1.11.11.1-1.21.21.21.4-1.2-1.81.61.4-1.6-1.0-2.00.81.81.4-1.61.7
Locomotion velocity, hab. session 21.52.04.10.5-1.40.9-1.11.11.1-1.21.21.21.3-1.3-1.81.71.4-1.7-1.1-2.01.01.91.5-1.81.8
Novel to familiar place preference ratio1.11.22.6-0.91.6-0.91.0-1.0-1.01.0-1.0-1.0-1.01.11.3-1.3-1.11.30.61.4-0.5-1.4-1.31.1-1.1
Novelty place preference1.41.52.5-0.91.6-1.11.1-1.1-1.11.2-1.2-1.2-1.11.31.4-1.4-1.21.40.41.4-0.4-1.5-1.41.0-1.2
Time in novel zone, NPP test1.41.52.5-1.11.6-1.21.2-1.2-1.21.3-1.4-1.4-1.21.31.3-1.4-1.31.40.11.3-0.1-1.3-1.40.8-1.0
Total zone transitions, NPP test0.71.03.0-0.4-0.50.1-0.40.40.4-0.50.50.50.7-0.6-1.31.20.8-1.1-1.4-1.41.31.61.0-1.71.7
Total locomotion distance, NPP test1.82.56.3-0.0-1.20.5-0.90.90.9-1.00.90.91.2-1.1-2.01.81.3-1.7-2.0-2.21.82.41.6-2.52.5
Locomotion velocity, NPP test1.31.95.3-0.2-1.00.3-0.60.60.6-0.80.70.71.0-0.8-1.81.51.1-1.5-1.9-1.91.72.21.4-2.32.2
Intraocular pressure0.60.83.01.3-0.40.6-0.30.30.3-0.20.20.20.00.00.6-0.7-0.20.61.70.7-1.7-1.3-0.71.7-1.5
Delta distance traveled before/after self-admin0.70.71.31.0-1.20.9-1.01.01.0-1.01.01.00.8-0.9-0.70.91.0-1.10.6-0.8-0.60.40.5-0.00.3
Delta ambulatory time before/after self-admin0.20.20.60.2-0.50.4-0.50.50.5-0.50.50.50.5-0.5-0.40.60.6-0.80.2-0.5-0.20.20.3-0.10.3
Parametrial fat weight1.33.011.11.10.70.50.3-0.3-0.30.3-0.3-0.3-0.30.61.6-1.8-1.11.92.82.0-3.0-2.6-1.93.3-3.2
Pavlov. Cond. lever latency6.58.211.9-2.43.2-2.83.0-3.0-3.03.1-3.2-3.2-2.83.33.1-3.4-3.23.40.12.9-0.3-3.0-3.41.9-2.5
Pavlov. Cond. magazine entry latency0.30.41.01.0-0.70.9-0.70.70.7-0.70.80.80.4-0.8-0.20.50.5-0.50.6-0.2-0.20.20.80.2-0.0
Pavlov. Cond. change in total contacts4.04.36.92.6-2.42.6-2.42.42.4-2.52.52.52.2-2.5-1.92.12.2-2.11.1-1.6-0.81.32.1-0.30.8
Pavlov. Cond. index score2.73.45.61.7-2.11.9-1.91.91.9-1.92.02.01.7-2.2-1.92.21.9-2.1-0.1-1.90.41.92.4-1.21.6
Pavlov. Cond. latency score3.94.98.21.9-2.42.2-2.32.32.3-2.32.42.42.0-2.6-2.32.72.4-2.6-0.2-2.30.52.42.9-1.62.0
Pavlov. Cond. lever contacts5.36.49.12.3-2.92.6-2.72.72.7-2.72.82.82.4-3.0-2.73.02.7-2.90.1-2.50.12.53.0-1.52.0
Pavlov. Cond. magazine entry number0.50.61.2-1.10.9-1.10.9-0.9-0.90.9-0.9-0.9-0.61.00.4-0.7-0.70.7-0.60.40.3-0.3-1.0-0.1-0.1
Pavlov. Cond. intertrial magazine entries1.51.83.11.2-1.71.1-1.31.31.3-1.41.31.31.5-1.4-1.61.61.5-1.6-0.2-1.50.21.61.3-1.11.3
Pavlov. Cond. lever-magazine prob. diff.2.12.64.51.6-1.91.7-1.71.71.7-1.71.81.81.5-1.9-1.61.91.7-1.8-0.0-1.60.31.72.1-1.01.3
Pavlov. Cond. response bias1.51.82.81.5-1.71.6-1.51.51.5-1.51.51.51.2-1.7-1.21.51.4-1.40.3-1.2-0.21.11.7-0.50.8
Pavlov. Cond. lever latency0.50.72.1-1.51.0-1.10.9-0.9-0.91.0-1.0-0.9-0.80.90.2-0.6-0.80.6-1.2-0.01.10.2-0.5-0.60.3
Pavlov. Cond. magazine entry latency0.50.61.51.0-0.51.1-0.60.60.6-1.11.21.10.5-0.9-0.10.60.8-0.61.20.4-0.6-0.00.80.5-0.1
Pavlov. Cond. change in total contacts0.61.02.81.7-1.31.3-1.11.11.1-1.21.21.21.1-1.2-0.50.81.0-0.81.2-0.1-1.10.10.70.5-0.1
Pavlov. Cond. index score0.70.92.41.5-0.91.3-1.01.01.0-1.21.21.10.9-1.1-0.20.60.9-0.61.60.2-1.3-0.20.60.8-0.4
Pavlov. Cond. latency score0.60.81.71.3-0.81.2-0.90.90.9-1.11.21.10.7-1.0-0.20.70.9-0.71.30.2-0.9-0.00.80.5-0.1
Pavlov. Cond. lever contacts0.50.71.81.4-1.01.1-1.01.01.0-1.01.11.00.8-0.9-0.30.70.9-0.71.1-0.0-1.0-0.00.60.4-0.1
Pavlov. Cond. magazine entry number1.01.23.2-1.81.1-1.61.1-1.1-1.11.3-1.4-1.4-1.01.20.3-0.6-1.00.6-1.8-0.21.40.3-0.6-1.00.5
Pavlov. Cond. intertrial magazine entries0.60.93.0-1.40.6-1.30.9-0.9-0.91.1-1.2-1.1-0.71.00.1-0.5-0.80.4-1.7-0.41.20.3-0.6-0.90.5
Pavlov. Cond. lever-magazine prob. diff.0.81.12.91.7-1.11.4-1.11.11.1-1.31.31.21.0-1.2-0.30.71.0-0.71.60.2-1.3-0.20.70.8-0.4
Pavlov. Cond. response bias0.60.92.41.5-1.11.2-1.01.01.0-1.11.11.01.0-1.0-0.30.60.9-0.61.30.0-1.2-0.20.40.7-0.3
Time in closed arm before self-admin3.03.816.84.1-2.52.6-2.02.02.0-1.91.91.91.7-1.7-0.90.81.3-0.72.8-0.7-2.8-0.40.41.8-1.2
Time in closed arm after self-admin2.12.38.31.50.40.60.0-0.0-0.00.1-0.2-0.2-0.10.51.2-1.4-0.71.32.71.5-2.7-2.4-1.82.9-2.6
Time in open arm before self-admin1.92.15.1-0.5-0.80.4-1.00.90.9-1.01.01.01.1-1.2-1.71.91.5-2.0-1.4-1.71.32.11.7-2.12.3
Time in open arm after self-admin5.15.612.01.3-2.71.3-1.71.71.7-1.91.91.91.7-2.1-2.72.92.2-2.7-1.9-3.02.13.53.1-3.13.2
Bone: periosteal estimation0.71.54.02.0-1.71.6-1.41.41.4-1.21.11.11.5-0.9-0.60.30.8-0.31.7-0.4-1.9-0.5-0.31.3-0.9
Bone: periosteal perimeter1.93.38.32.9-2.32.3-2.12.12.1-1.81.71.72.0-1.5-0.80.61.2-0.62.6-0.5-2.8-0.70.01.9-1.3
Bone: post-yield work0.10.10.70.2-0.8-0.0-0.10.10.1-0.10.0-0.00.4-0.0-0.40.20.1-0.2-0.5-0.50.30.4-0.0-0.40.4
Progressive ratio test 1 active lever presses0.70.94.10.30.31.0-0.90.90.9-0.90.90.90.8-0.8-0.00.30.9-0.32.0-0.1-2.0-0.8-0.31.1-0.7
Progressive ratio test 1 breakpoint0.70.83.70.30.31.0-0.90.90.9-0.90.90.90.7-0.8-0.00.30.9-0.31.9-0.2-1.9-0.7-0.31.1-0.6
Progressive ratio test 1 inactive lever presses0.60.92.61.6-0.91.4-1.01.01.0-1.01.00.91.1-0.9-0.60.30.7-0.31.4-0.7-1.4-0.2-0.10.8-0.6
Progressive ratio test 2 active lever presses0.80.92.3-0.91.5-0.30.5-0.4-0.40.5-0.5-0.5-0.60.61.1-1.0-0.61.11.21.1-1.2-1.5-1.31.3-1.3
Progressive ratio test 2 breakpoint0.70.82.3-0.91.5-0.30.5-0.5-0.50.5-0.5-0.5-0.60.61.0-1.0-0.61.11.01.0-1.0-1.4-1.21.2-1.2
Progressive ratio test 2 inactive lever presses0.20.31.40.6-0.30.7-0.50.50.5-0.40.40.40.4-0.30.1-0.10.20.21.20.1-1.2-0.5-0.31.0-0.9
Incentive Sensitization - Responses2.53.68.0-2.52.8-1.81.8-1.8-1.81.9-2.0-1.9-1.81.92.1-2.1-2.02.10.12.1-0.1-1.9-1.91.2-1.6
Incentive Sensitization - Breakpoint3.03.98.3-2.62.9-2.02.0-2.0-2.02.1-2.1-2.0-2.02.12.1-2.2-2.12.2-0.12.10.1-1.9-1.91.1-1.5
Sum of active levers in priming session hrs 5-61.11.14.5-1.80.3-1.00.6-0.6-0.60.5-0.5-0.5-0.30.4-0.40.3-0.2-0.4-2.1-0.52.11.30.6-1.81.5
Progressive ratio0.20.40.8-0.40.4-0.50.7-0.7-0.70.6-0.6-0.6-0.90.80.7-0.8-0.80.9-0.30.80.1-0.4-0.30.4-0.6
Food seeking constrained by brief footshock0.20.21.1-1.00.9-0.60.5-0.6-0.60.3-0.2-0.3-0.70.30.4-0.2-0.20.2-0.50.30.40.0-0.1-0.30.2
Seeking ratio, punishment vs. effort0.30.51.30.1-0.40.3-0.40.40.4-0.60.50.60.6-0.8-0.90.90.8-0.9-0.5-0.90.61.00.6-1.11.1
Retroperitoneal fat weight1.04.115.23.9-1.92.7-2.01.91.9-1.71.71.71.8-1.4-0.2-0.20.80.13.2-0.0-3.6-1.5-0.62.8-2.2
Reaction time number correct2.24.18.01.7-2.51.5-1.81.81.8-1.81.81.81.8-2.0-2.62.42.0-2.4-1.1-2.80.92.72.2-2.02.2
Reaction time mean minus median0.00.10.3-0.60.5-0.1-0.10.20.2-0.20.30.3-0.2-0.3-0.20.50.4-0.5-0.2-0.10.10.40.4-0.40.5
Reaction time mean minus median AUC0.00.10.4-0.60.4-0.2-0.10.20.2-0.10.20.2-0.2-0.3-0.10.40.4-0.5-0.1-0.1-0.20.20.2-0.30.3
Reaction time num false alarms0.20.31.6-0.60.90.1-0.40.50.5-0.40.40.30.4-0.3-0.20.40.7-0.51.20.3-1.3-0.6-0.20.6-0.2
Reaction time num false alarms AUC0.20.31.3-0.60.9-0.1-0.20.30.3-0.10.10.10.2-0.1-0.00.20.4-0.31.10.3-1.2-0.7-0.40.6-0.3
Reaction time trials correct on left2.24.18.01.7-2.51.5-1.81.81.8-1.81.81.81.8-2.0-2.62.42.0-2.4-1.1-2.80.92.72.2-2.02.2
Reaction time trials on left2.34.38.21.7-2.51.6-1.91.91.9-1.81.81.81.8-2.0-2.62.42.1-2.4-1.0-2.90.82.72.2-2.02.2
Reaction time mean1.32.04.5-0.91.7-0.91.0-1.0-1.01.1-1.1-1.1-1.21.11.7-1.6-1.21.51.32.0-1.4-2.1-1.61.9-1.9
Reaction time mean AUC1.52.44.6-1.62.1-1.41.4-1.4-1.41.4-1.4-1.5-1.61.41.9-1.7-1.41.60.72.0-0.9-2.0-1.71.5-1.6
Median of all reaction times2.53.67.5-1.12.0-1.21.5-1.5-1.51.6-1.6-1.6-1.61.72.3-2.2-1.82.11.42.5-1.5-2.7-2.22.4-2.5
Reaction time omissions0.30.41.8-0.70.60.2-0.60.60.6-0.60.70.60.5-0.6-0.70.71.1-0.81.1-0.3-1.30.0-0.10.4-0.0
Reaction time false alarm rate0.70.92.7-1.01.6-0.50.3-0.3-0.30.4-0.4-0.5-0.30.50.8-0.6-0.20.51.61.3-1.5-1.6-1.11.4-1.2
Reaction time premature initiation rate1.21.73.60.1-1.10.7-1.01.01.0-1.21.31.30.9-1.2-1.21.71.6-1.9-0.9-1.40.81.71.6-1.71.9
Reaction time premature initiations2.54.58.00.9-2.11.4-1.81.91.9-2.02.02.11.7-2.1-2.32.72.4-2.8-1.2-2.60.92.72.5-2.42.6
Std. dev. reaction times0.10.20.7-0.70.8-0.0-0.30.40.4-0.30.30.3-0.1-0.3-0.10.40.5-0.40.70.2-0.8-0.20.00.3-0.1
Reaction time trials completed2.34.38.21.7-2.51.6-1.91.91.9-1.81.81.81.8-2.0-2.62.42.1-2.4-1.0-2.90.82.72.2-2.02.2
Reaction time trials AUC2.03.77.11.7-2.41.6-1.81.81.8-1.81.71.71.8-1.9-2.42.21.9-2.3-0.9-2.70.62.42.1-1.82.0
Run reversals in cocaine runway, females1.01.03.11.7-1.51.1-1.00.90.9-0.90.90.71.0-0.7-0.10.30.7-0.31.8-0.1-1.7-0.7-0.11.2-0.9
Run reversals in cocaine runway, males0.60.62.5-1.60.5-0.70.3-0.3-0.30.1-0.1-0.2-0.10.0-0.50.60.3-0.7-1.5-0.21.31.10.7-1.51.3
Latency to leave start box in cocaine runway0.00.00.20.10.1-0.10.3-0.2-0.20.1-0.1-0.1-0.50.20.2-0.3-0.30.2-0.10.10.20.10.00.1-0.2
Latency to leave start box in cocaine runway, F0.30.30.70.9-0.60.7-0.50.70.7-0.70.70.80.5-0.6-0.70.50.6-0.60.3-0.6-0.20.50.5-0.00.1
Latency to leave start box in cocaine runway, M2.62.43.7-1.61.8-1.71.8-1.8-1.81.7-1.6-1.8-1.91.81.8-1.8-1.71.7-0.51.60.5-1.1-1.30.6-1.0
Std. dev. time between licks in bursts0.81.12.91.7-1.51.4-1.21.21.2-1.11.01.11.3-0.9-0.50.40.8-0.51.6-0.4-1.7-0.3-0.11.0-0.7
Total sessions with >9 infusions1.11.35.91.00.11.4-1.01.01.0-1.01.00.91.0-0.8-0.1-0.20.60.32.40.0-2.4-1.0-0.61.8-1.4
Short access day 1 total inactive lever presses1.01.35.11.2-0.20.30.5-0.5-0.50.4-0.4-0.5-0.40.70.9-1.6-1.31.71.31.2-1.4-1.4-1.12.1-2.3
Short access day 10 total inactive lever presses0.00.10.20.0-0.3-0.30.2-0.2-0.20.3-0.2-0.2-0.30.20.2-0.1-0.2-0.1-0.40.00.50.10.3-0.20.1
Short access day 1 total infusions1.21.65.32.3-1.11.8-1.21.21.2-1.21.11.21.2-1.0-0.40.00.60.12.2-0.4-2.2-0.6-0.21.7-1.3
Short access day 10 total infusions0.30.31.10.9-0.40.7-0.40.40.4-0.30.30.30.1-0.20.1-0.4-0.20.71.0-0.2-1.0-0.5-0.41.0-1.0
Short access total infusions0.60.72.90.50.30.7-0.30.30.3-0.20.20.20.2-0.00.5-0.7-0.20.91.70.4-1.7-1.2-0.91.7-1.5
Short access day 1 locomotion2.02.510.12.5-0.51.8-1.01.01.0-1.00.90.90.8-0.60.4-0.60.30.83.20.3-3.2-1.7-1.02.7-2.2
Short access day 10 total locomotion2.44.48.83.0-2.72.5-2.52.52.5-2.32.32.32.0-2.3-1.82.12.3-2.11.2-2.3-1.21.21.7-0.30.8
Short access total locomotion1.11.34.11.4-0.51.6-1.41.31.3-1.21.21.21.1-1.1-0.40.51.0-0.32.0-0.6-2.0-0.50.01.2-0.7
One hour access (0.3 mA shock)0.91.02.20.01.0-0.30.7-0.6-0.60.7-0.7-0.7-0.90.81.3-1.3-1.01.31.01.1-1.0-1.5-1.31.4-1.5
Compulsive drug intake1.41.72.8-1.41.4-1.71.5-1.5-1.51.6-1.6-1.5-1.61.51.3-1.3-1.41.0-1.11.11.1-0.6-0.6-0.1-0.3
One hour access (shock baseline)0.60.94.30.80.30.9-0.40.40.4-0.40.40.40.2-0.20.5-0.50.00.72.00.6-2.1-1.3-1.01.8-1.5
Social response proportion2.02.33.61.7-1.21.8-1.81.81.8-1.81.81.81.5-1.7-1.41.41.8-1.41.9-0.8-1.70.51.00.60.1
Social responses2.22.84.31.7-2.11.6-1.92.02.0-1.71.71.71.7-1.8-2.02.01.9-1.90.3-1.8-0.31.61.6-0.91.3
Social time0.50.71.51.1-1.10.8-1.11.21.2-0.80.80.70.9-0.8-0.80.90.9-1.00.4-1.0-0.60.50.6-0.20.4
Soleus weight0.51.44.50.00.90.00.6-0.6-0.60.4-0.4-0.4-0.10.61.0-1.3-0.71.21.81.4-1.9-1.8-1.52.1-2.0
Bone: stiffness3.86.113.33.7-3.33.4-2.92.92.9-2.92.82.83.0-2.6-1.81.62.2-1.62.7-1.4-2.70.41.11.3-0.6
Tibialis anterior weight1.34.56.51.6-2.32.2-2.32.32.3-2.32.32.32.2-2.5-2.42.52.3-2.40.1-2.00.22.32.6-1.31.7
Time to tail flick, vehicle, before self-admin1.61.72.9-1.71.4-1.41.5-1.4-1.41.4-1.3-1.3-1.41.31.5-1.2-1.41.5-0.11.30.1-1.2-1.20.7-1.0
Time to tail flick, vehicle, after self-admin0.20.21.51.2-0.70.8-0.40.40.4-0.50.50.50.6-0.3-0.4-0.10.10.30.5-0.1-0.50.0-0.00.5-0.4
Time to tail flick, test, before self-admin0.60.73.50.60.10.6-0.60.60.6-0.50.50.50.6-0.50.20.10.6-0.31.90.4-1.9-1.0-0.61.2-0.8
Time to tail flick, test, after self-admin3.13.27.8-2.82.3-2.12.0-2.0-2.02.0-2.0-2.0-1.82.01.8-1.9-1.91.8-0.51.80.6-1.4-1.50.6-1.0
Delta time to tail flick, vehicle, before/after SA1.21.13.01.7-1.51.3-1.11.11.1-1.11.11.11.2-1.0-1.40.80.8-0.9-0.2-1.00.11.21.1-0.50.7
Delta time to tail flick, test, before/after SA1.61.63.3-1.81.2-1.51.4-1.5-1.51.5-1.5-1.5-1.41.40.9-1.1-1.51.2-1.50.71.5-0.2-0.6-0.4-0.1
Tibia length0.82.14.12.0-1.92.0-1.61.71.7-1.81.81.81.5-1.7-0.91.31.5-1.31.2-0.8-1.00.51.20.30.1
Ambulatory time before self-admin1.21.76.82.6-1.91.7-1.31.31.3-1.51.51.51.6-1.4-1.11.01.2-0.81.3-0.9-1.30.30.50.5-0.0
Ambulatory time after self-admin3.74.49.73.1-3.02.4-2.22.22.2-2.42.42.42.4-2.3-2.02.12.3-2.21.4-1.8-1.31.11.4-0.10.7
Bone: tissue strength0.10.10.40.4-0.60.2-0.30.30.3-0.10.10.10.4-0.1-0.30.10.10.00.1-0.3-0.40.0-0.30.1-0.0
Total heroin consumption0.10.11.2-1.10.6-0.40.1-0.1-0.10.1-0.1-0.1-0.00.00.30.20.4-0.30.30.0-0.5-0.4-0.4-0.00.2
Bone: trabecular number2.03.36.02.0-1.82.3-1.81.81.8-2.42.42.41.9-2.2-1.72.02.2-1.91.3-1.3-0.51.21.8-0.30.9
Bone: trabecular spacing0.70.91.4-1.00.5-1.11.1-1.1-1.11.1-1.2-1.2-0.81.20.9-1.1-1.11.0-0.50.7-0.0-0.6-1.10.4-0.7
Bone: trabecular thickness2.12.73.91.8-1.31.9-1.91.91.9-2.02.01.91.9-1.9-1.81.71.9-1.60.7-1.5-0.41.11.3-0.51.0
Bone: trabecular tissue density0.30.51.70.2-1.10.0-0.30.30.3-0.20.10.10.6-0.2-0.80.50.2-0.4-1.3-1.10.91.10.4-1.10.9
Water consumed over 24 hours0.91.22.00.3-1.10.8-1.01.01.0-1.11.11.01.0-1.1-1.31.41.3-1.4-0.3-1.10.41.41.2-1.11.3
Number of responses in last shaping day0.30.41.11.0-0.80.8-0.70.60.6-0.70.70.60.7-0.7-0.70.40.4-0.20.0-0.9-0.20.50.5-0.00.1