Hub : Genes

Ugt2b37

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Ugt2b37 0.89 0.08 0.0e+00 0.54 0.49 0.56 0.56 1.2e-70 3.0e-61 5.8e-75 7.3e-76
2 Liver intron excision ratio chr14_20718303_20719756 0.59 0.13 0.0e+00 0.47 0.44 0.48 0.48 8.4e-59 4.7e-53 7.1e-60 1.2e-59
3 Liver intron excision ratio chr14_20768768_20770242 0.24 0.15 1.1e-16 0.13 0.11 0.11 0.12 2.0e-14 4.7e-12 3.1e-12 1.1e-13
4 Liver intron excision ratio chr14_20721564_20779363 0.15 0.09 5.6e-14 0.07 0.1 0.1 0.1 2.8e-08 6.5e-11 4.0e-11 1.1e-10
5 Liver intron excision ratio chr14_20820793_20828959 0.88 0.04 0.0e+00 0.56 0.5 0.62 0.62 8.7e-76 4.2e-64 3.4e-87 8.7e-88
6 Liver mRNA stability Ugt2b37 0.06 0.04 3.6e-05 0.04 0.03 0.03 0.03 5.1e-05 3.7e-04 1.5e-04 1.9e-04
7 Liver intron excision ratio chr14_20818050_20819532 0.61 0.14 0.0e+00 0.37 0.37 0.42 0.42 1.3e-42 1.3e-43 1.6e-50 6.4e-51
8 Liver intron excision ratio chr14_20721564_20757388 0.81 0.09 0.0e+00 0.48 0.42 0.5 0.49 2.6e-60 1.5e-50 4.7e-63 2.6e-62
9 Liver intron excision ratio chr14_20768768_20819532 0.03 0.03 7.2e-03 0.01 0.01 0.01 0 8.9e-03 3.0e-02 2.5e-02 8.4e-02
10 Liver intron excision ratio chr14_20771925_20779363 0.87 0.06 0.0e+00 0.5 0.46 0.56 0.56 1.8e-64 5.1e-56 1.7e-74 4.3e-74
11 Liver intron excision ratio chr14_20721564_20733031 0.89 0.03 0.0e+00 0.42 0.34 0.44 0.42 3.2e-50 1.5e-39 7.1e-54 8.3e-50
12 Liver intron excision ratio chr14_20718303_20770242 0.88 0.03 0.0e+00 0.54 0.45 0.56 0.56 1.6e-70 1.2e-54 1.1e-74 5.0e-74

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.30.5-0.6-0.60.7-0.5-0.6-0.0-0.6-0.60.40.5-0.5-0.6
Area under the delay curve0.10.10.6-0.2-0.10.1-0.30.0-0.8-0.1-0.2-0.40.3-0.3-0.4
BMI with tail1.54.87.0-2.3-2.22.1-2.6-2.0-2.3-2.0-2.41.32.4-2.0-2.3
BMI without tail0.20.54.4-0.2-0.10.1-0.7-0.0-2.10.1-0.3-0.40.5-0.0-0.8
Body weight0.20.93.2-0.9-0.70.6-1.1-0.6-1.8-0.5-1.00.21.0-0.6-1.1
Weight adjusted by age1.31.51.9-1.3-1.31.4-0.9-1.30.8-1.4-1.21.31.2-1.3-1.2
Bone surface0.10.21.5-0.3-0.20.30.1-0.31.2-0.1-0.00.50.0-0.0-0.2
Bone volume0.10.10.40.30.4-0.20.40.30.60.40.4-0.2-0.30.40.2
Breakpoint value in progressive ratio session0.10.10.40.40.4-0.40.10.4-0.40.30.4-0.7-0.30.30.2
Number of licking bursts0.10.20.4-0.3-0.30.3-0.5-0.40.1-0.3-0.40.60.4-0.5-0.6
Context. condit. distance diff. score0.81.07.50.30.5-0.21.00.42.70.40.70.3-0.80.60.9
Locomotion velocity, session 11.01.02.8-0.8-0.90.6-1.2-0.8-1.7-0.9-1.10.21.1-1.0-1.2
Locomotion distance, session 10.20.30.40.70.5-0.60.60.50.50.50.6-0.3-0.60.50.4
Locomotion velocity, session 20.10.10.30.30.3-0.30.50.30.40.30.3-0.4-0.40.30.4
Locomotion distance, session 20.10.10.30.50.4-0.40.40.4-0.00.40.4-0.2-0.40.30.2
Locomotion velocity, session 30.50.61.01.00.8-0.80.90.90.60.60.8-0.6-0.80.70.8
Locomotion distance, session 30.00.00.30.1-0.0-0.10.10.20.6-0.20.10.3-0.00.0-0.1
Stereotopy head waving bouts, day 30.70.81.2-0.9-0.90.9-1.0-0.9-0.9-0.9-1.10.51.0-1.1-1.0
Stereotopy head waving duration, day 30.10.10.3-0.2-0.20.3-0.2-0.3-0.6-0.3-0.40.00.3-0.6-0.3
Locomotion velocity, session 71.92.13.11.71.6-1.61.31.6-0.41.61.5-1.6-1.41.51.1
Locomotion distance, session 71.21.52.01.41.4-1.31.31.30.81.41.4-0.8-1.21.31.0
Stereotopy head waving bouts, day 70.20.30.5-0.5-0.60.7-0.3-0.6-0.0-0.5-0.50.60.5-0.6-0.4
Stereotopy head waving duration, day 70.40.51.4-0.6-0.70.6-0.8-0.6-1.2-0.5-0.70.30.7-0.7-0.7
Locomotion velocity, session 80.10.10.90.00.10.00.50.01.00.00.1-0.1-0.30.00.5
Locomotion distance, session 81.11.76.31.01.1-0.81.61.02.51.01.2-0.3-1.41.01.3
Degree of sensitization distance1.21.22.01.11.3-1.11.21.10.51.41.2-0.8-1.11.21.0
Degree of sensitization stereotypy0.00.00.2-0.1-0.30.3-0.0-0.20.1-0.10.00.40.1-0.1-0.0
Conditioned locomotion0.50.61.6-0.6-0.71.0-0.7-0.80.5-0.6-0.61.20.7-0.7-0.9
Cocaine response after cond. corrected0.60.71.11.00.9-1.10.80.90.20.90.9-0.8-0.80.90.7
Cocaine response after cond. not corrected0.70.80.91.00.9-1.00.90.90.80.90.9-0.7-0.90.90.8
Cocaine response before conditioning0.10.10.6-0.4-0.20.5-0.1-0.40.8-0.3-0.30.40.1-0.3-0.1
Saline control response0.70.91.21.01.0-1.01.01.00.41.11.0-0.8-1.01.11.1
Bone: connectivity density0.40.70.9-0.9-0.90.9-0.9-0.9-0.2-0.9-1.00.60.8-0.8-0.7
Bone: cortical apparent density0.60.87.00.20.1-0.2-0.40.2-2.6-0.0-0.2-1.30.1-0.10.1
Bone: cortical area0.30.41.00.50.7-0.60.50.5-0.21.00.6-0.8-0.50.80.6
Bone: cortical porosity1.71.92.6-1.5-1.51.5-1.2-1.51.0-1.5-1.41.61.3-1.3-1.0
Bone: cortical porosity2.83.04.0-2.0-1.91.9-1.7-1.90.4-1.8-1.81.81.7-1.7-1.5
Bone: cortical thickness0.30.50.8-0.8-0.70.8-0.9-0.8-0.2-0.5-0.70.60.8-0.6-0.6
Bone: cortical thickness0.30.32.00.30.3-0.10.60.31.40.40.50.3-0.50.30.7
Bone: cortical tissue density0.60.77.00.1-0.0-0.1-0.50.1-2.7-0.1-0.4-1.20.3-0.2-0.0
Condit. Reinf. active minus inactive responses0.80.91.5-1.0-0.90.8-1.2-0.9-0.8-0.8-1.00.71.0-0.7-1.1
Condit. Reinf. active-inactive response ratio2.93.24.3-2.1-1.91.9-1.9-2.0-0.2-1.8-1.81.71.8-1.8-1.7
Condit. Reinf. active responses0.00.00.10.20.1-0.3-0.10.2-0.30.10.1-0.1-0.00.2-0.1
Condit. Reinf. inactive responses2.22.63.61.91.8-1.81.61.80.31.71.7-1.2-1.61.71.4
Incentive salience index mean0.10.10.4-0.3-0.30.2-0.5-0.3-0.6-0.2-0.30.10.4-0.1-0.4
Condit. Reinf. lever presses0.00.00.00.20.1-0.1-0.00.10.10.10.20.0-0.10.10.1
Condit. Reinf. active minus inactive responses0.10.10.20.40.3-0.30.30.3-0.20.20.2-0.4-0.30.10.2
Condit. Reinf. active-inactive response ratio0.10.20.30.60.4-0.50.30.4-0.30.40.4-0.5-0.30.30.2
Condit. Reinf. active responses0.10.20.30.50.5-0.30.60.40.30.40.3-0.4-0.50.20.5
Condit. Reinf. inactive responses0.40.61.20.50.7-0.50.90.71.10.60.6-0.5-0.90.60.9
Condit. Reinf. lever presses0.60.82.00.80.8-0.61.00.71.40.81.0-0.3-1.00.91.0
Condit. Reinf. lever reinforcers received0.20.30.60.50.5-0.30.70.50.80.40.5-0.3-0.70.30.6
Conditioned reinforcement - actives0.20.20.8-0.4-0.30.5-0.2-0.40.9-0.3-0.30.80.4-0.3-0.6
Conditioned reinforcement - inactives1.21.31.71.21.2-1.31.11.20.71.11.3-0.9-1.21.31.1
Conditioned locomotion0.10.10.6-0.00.10.00.20.10.70.20.10.2-0.10.20.1
Patch foraging indifference point 0 sec0.40.61.40.90.8-0.70.90.8-0.10.70.6-1.2-0.90.61.0
Patch foraging indifference point AUC2.32.63.61.91.8-1.91.31.8-0.91.61.8-1.9-1.31.71.0
Delay disc. indifference point, 0s delay0.20.20.7-0.3-0.40.3-0.6-0.3-0.9-0.3-0.40.00.5-0.4-0.5
Delay disc. indifference point, 16s delay0.90.92.6-1.0-0.80.8-1.2-0.6-1.6-0.8-0.90.01.1-0.9-1.1
Delay disc. indifference point, 2s delay2.62.94.11.91.8-1.81.81.8-0.11.91.8-2.0-1.61.71.4
Delay disc. indifference point, 24s delay0.10.10.3-0.5-0.30.5-0.2-0.30.0-0.4-0.40.20.3-0.5-0.5
Delay disc. indifference point, 4s delay0.40.41.60.50.5-0.60.20.6-1.30.50.5-1.2-0.30.40.3
Delay disc. indifference point, 8s delay1.61.62.3-1.4-1.21.2-1.5-1.1-1.0-1.3-1.30.61.4-1.3-1.5
Indifference point function ln k0.81.11.6-1.3-1.21.2-0.8-1.20.8-1.0-1.11.00.9-1.0-0.7
Indifference point function log k0.81.11.6-1.3-1.21.2-0.8-1.20.8-1.0-1.11.00.9-1.0-0.7
Patch foraging total patch changes 0 sec0.40.71.50.90.8-0.70.90.8-0.20.70.5-1.2-0.90.71.0
Patch foraging total patch changes 12 sec0.40.51.50.70.8-0.50.30.7-1.20.70.5-1.0-0.30.50.2
Patch foraging total patch changes 18 sec0.10.20.50.50.4-0.50.10.4-0.70.10.4-0.7-0.20.30.1
Patch foraging total patch changes 24 sec0.80.91.61.21.1-1.20.91.20.11.01.0-0.7-1.01.00.7
Patch foraging total patch changes 6 sec1.21.82.51.61.5-1.31.31.5-0.61.51.3-1.4-1.31.31.1
Patch foraging time to switch 0 sec3.45.26.5-2.6-2.52.4-2.5-2.4-0.8-2.4-2.51.92.3-2.4-2.1
Patch foraging water rate 0 sec1.52.43.61.81.8-1.41.81.60.21.91.7-1.3-1.51.61.3
Patch foraging water rate 12 sec0.50.81.70.80.8-0.61.10.71.31.00.9-0.1-0.90.91.0
Patch foraging water rate 18 sec2.22.94.71.81.7-1.42.21.61.41.81.7-1.1-1.91.61.9
Patch foraging water rate 24 sec1.42.04.81.41.4-0.81.91.22.21.41.4-0.4-1.51.31.4
Patch foraging water rate 6 sec0.60.91.61.01.0-0.91.01.00.21.31.2-0.8-0.91.20.8
Seeking ratio, delayed vs. immediate footshock1.11.21.71.21.0-1.31.01.10.91.01.2-0.9-1.21.11.2
Distance traveled before self-admin0.40.40.60.70.7-0.80.70.60.60.80.7-0.5-0.60.60.6
Distance traveled after self-admin2.93.24.62.01.8-1.72.11.71.81.82.0-1.1-1.91.71.8
Extensor digitorum longus weight10.340.547.5-6.9-6.86.8-6.6-6.8-0.8-6.6-6.56.66.6-6.6-6.3
Bone: elastic displacement0.50.62.0-0.6-0.70.8-0.3-0.71.4-0.8-0.41.20.4-0.6-0.3
Bone: elastic work0.30.53.0-0.4-0.50.5-0.1-0.51.7-0.6-0.21.00.1-0.30.2
Bone: endosteal estimation1.83.85.22.02.1-1.92.31.91.12.12.0-1.9-2.12.01.9
Bone: endosteal perimeter0.40.91.20.91.0-0.91.10.80.91.01.0-0.9-1.01.00.8
Epididymis fat weight0.10.32.0-0.4-0.20.2-0.4-0.1-1.4-0.1-0.5-0.10.5-0.2-0.7
Delta time in closed arm before/after self-admin1.21.21.8-1.3-1.10.9-1.2-1.2-0.4-1.0-1.20.91.3-1.1-1.1
Delta time in open arm before/after self-admin1.31.21.91.31.2-1.21.01.40.00.81.0-1.3-1.21.01.1
Diff in mean of infusions in LGA sessions0.00.00.3-0.1-0.20.3-0.0-0.10.5-0.2-0.10.20.1-0.2-0.1
Delay discount exponential model param0.10.10.50.0-0.10.10.1-0.20.7-0.0-0.00.6-0.10.10.1
Extinction: sum of active levers before priming0.60.61.10.80.8-0.81.00.91.10.40.8-0.4-0.90.50.8
Active lever presses in extinction session 60.50.50.90.90.9-0.90.80.9-0.10.60.8-0.8-0.70.60.5
Bone: final force0.10.10.30.30.3-0.20.30.20.10.50.2-0.5-0.20.30.2
Bone: final moment0.10.10.30.30.4-0.20.30.20.10.60.2-0.4-0.20.40.3
Food consumed during 24 hour testing period2.42.94.11.91.7-1.71.91.81.81.72.0-0.5-1.81.71.4
Glucose1.11.62.51.41.4-1.31.61.30.41.31.4-1.1-1.31.21.2
Heart weight0.40.61.0-0.9-0.71.0-0.6-0.9-0.1-0.5-0.81.00.8-0.7-0.8
Delay discount hyperbolic model param0.20.20.8-0.4-0.40.4-0.2-0.50.7-0.4-0.30.90.2-0.2-0.2
Intermittent access intake day 1-15 change1.61.63.4-1.3-1.21.5-0.9-1.31.3-1.0-0.91.81.2-1.0-1.4
Intermittent access intake escalation0.80.82.0-0.8-0.81.0-0.5-0.81.3-0.6-0.51.40.8-0.6-1.0
Intermittent access intake escalation 20.10.10.70.10.20.10.30.10.80.20.30.2-0.00.2-0.2
Intermitt. access day 1 inactive lever presses1.01.11.61.11.1-1.31.01.10.60.81.1-1.1-1.11.10.8
Intermitt. access day 15 inactive lever presses1.41.62.31.41.3-1.51.41.40.61.31.4-0.6-1.41.21.2
Intermitt. access escalation Index1.21.01.7-1.0-1.11.0-0.9-1.10.4-1.2-0.91.30.9-1.2-1.0
Intermittent access day 1 total infusions0.00.00.10.10.1-0.10.20.20.3-0.00.10.3-0.20.00.2
Intermittent access day 15 total infusions0.20.21.7-0.0-0.00.10.30.01.30.10.20.8-0.10.1-0.2
Intermittent access terminal intake (last 3 days)0.30.31.50.40.5-0.30.70.41.20.50.70.2-0.40.50.1
Intermittent access total infusions0.10.10.50.10.1-0.00.20.20.70.10.20.3-0.10.20.0
Intermittent access day 1 locomotion0.00.00.10.10.2-0.10.30.20.20.20.1-0.0-0.30.20.3
Intermittent access day 15 total locomotion0.00.10.40.10.20.20.10.00.60.2-0.00.3-0.20.10.1
Intermittent access total locomotion0.10.10.2-0.3-0.20.4-0.3-0.3-0.0-0.1-0.30.40.2-0.2-0.2
Intermittent access standard deviation0.20.20.80.20.4-0.20.60.40.90.60.60.0-0.40.50.3
Left kidney weight0.20.71.20.70.9-0.60.90.80.91.10.9-0.2-0.80.90.6
Right kidney weight0.30.92.01.01.1-1.00.91.0-0.61.40.8-0.9-0.91.10.8
Cocaine induced anxiety0.10.10.1-0.3-0.20.3-0.3-0.2-0.3-0.3-0.20.00.3-0.2-0.3
Post-drug Anxiety0.20.21.80.00.1-0.2-0.30.2-1.30.10.0-0.60.10.1-0.2
Baseline Anxiety0.10.10.40.20.1-0.30.40.20.60.10.40.0-0.30.20.4
Tail length0.10.20.30.50.5-0.40.50.50.30.60.5-0.1-0.40.50.2
Length with tail0.62.02.71.51.6-1.61.61.50.51.61.4-1.1-1.51.51.3
Length without tail0.30.71.20.70.8-1.10.90.80.10.80.7-1.0-0.90.81.0
Times rat made contact with spout0.10.20.40.50.3-0.60.20.5-0.60.40.5-0.2-0.20.40.1
Lifetime Intake0.00.00.3-0.1-0.10.1-0.1-0.00.5-0.10.10.40.1-0.0-0.2
Liver weight, left1.82.84.32.11.8-1.81.62.0-1.11.71.7-1.7-1.61.51.4
Liver weight, right2.54.15.82.42.2-2.42.02.2-0.52.02.1-2.2-2.02.01.8
Locomotor activity0.50.82.30.70.9-0.81.30.81.50.70.90.0-0.90.80.7
Locomotor testing distance0.40.75.50.40.5-0.11.10.42.40.20.50.4-0.70.40.6
Locomotor testing rearing0.30.44.00.00.10.40.7-0.02.00.10.20.7-0.30.00.2
Locomotion in novel chamber0.00.00.20.20.0-0.2-0.00.1-0.50.00.10.10.10.0-0.2
Locomotion in novel chamber post-restriction0.80.92.61.00.9-1.10.61.0-1.00.90.8-1.6-0.70.90.7
Fecal boli incidents, locomotor time 11.11.21.9-1.2-1.31.4-0.9-1.20.7-1.2-1.01.31.0-1.1-0.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.2-0.20.2-0.0-0.10.1-0.5-0.30.20.1-0.5-0.3
Time >=10cm from walls, locomotor time 11.61.62.3-1.2-1.51.4-1.2-1.30.2-1.5-1.11.51.3-1.4-1.2
Bouts of movement, locomotor time 11.01.11.7-1.2-1.01.0-1.3-1.0-0.7-1.1-1.10.91.0-1.0-1.0
Total resting periods, locomotor time 10.70.81.4-1.0-0.90.8-1.2-0.9-0.7-0.9-0.90.70.9-0.8-0.9
Rest time, locomotor task time 10.70.82.60.80.7-0.81.00.71.60.50.9-0.3-1.00.70.9
Distance moved, locomotor task time 10.10.20.3-0.2-0.40.4-0.3-0.3-0.5-0.2-0.40.30.5-0.3-0.6
Vertical activity count, locomotor time 10.60.64.80.50.3-0.4-0.10.4-2.20.70.1-0.90.20.3-0.4
Time >=10cm from walls, locomotor time 20.30.31.3-0.4-0.50.5-0.2-0.31.1-0.7-0.21.00.2-0.6-0.3
Bouts of movement, locomotor time 20.10.10.40.30.3-0.50.20.30.00.20.1-0.7-0.40.20.5
Total resting periods, locomotor time 20.10.10.30.20.2-0.40.10.2-0.10.0-0.0-0.6-0.20.10.3
Rest time, locomotor task time 20.70.83.80.80.6-0.71.10.72.00.30.8-0.2-1.10.51.0
Distance moved, locomotor task time 21.21.42.2-1.3-1.21.2-1.3-1.2-0.9-1.0-1.20.91.4-1.0-1.5
Vertical activity count, locomotor time 20.30.43.1-0.0-0.10.1-0.5-0.0-1.80.3-0.2-0.50.50.1-0.6
Light reinforcement 10.51.01.31.11.2-1.00.81.1-0.01.11.1-1.1-0.91.10.7
Light reinforcement 20.00.10.1-0.2-0.20.1-0.3-0.1-0.3-0.3-0.30.30.1-0.3-0.1
Bone: marrow area1.73.65.01.92.0-1.92.21.81.12.02.0-1.8-2.02.01.8
Bone: maximum diameter0.10.11.0-0.10.1-0.0-0.2-0.1-1.00.4-0.1-0.50.20.1-0.3
Bone: maximum force0.30.60.90.60.8-0.60.90.60.60.90.7-0.8-0.70.80.9
Bone: maximum moment0.40.71.10.70.9-0.70.90.70.51.10.8-0.8-0.80.90.9
Mean time between licks in bursts4.56.48.0-2.8-2.72.6-2.7-2.7-1.2-2.5-2.82.12.6-2.7-2.4
Mean num. licks in bursts0.70.81.11.00.8-1.00.81.1-0.50.90.9-0.9-0.81.00.9
Cd content in liver1.61.72.3-1.5-1.41.3-1.4-1.5-0.6-1.4-1.41.01.4-1.3-1.2
Co content in liver0.10.10.30.20.3-0.50.20.2-0.10.20.0-0.4-0.30.20.4
Cu content in liver0.60.71.40.70.9-1.00.70.8-0.31.00.7-1.2-0.80.90.9
Fe content in liver0.70.82.4-1.0-0.80.5-1.1-0.7-1.5-0.7-1.10.00.9-0.7-0.7
K content in liver1.41.43.11.11.1-1.60.61.2-1.61.10.7-1.7-0.81.10.8
Mg content in liver1.31.33.91.11.1-1.40.41.1-2.01.00.6-1.7-0.61.00.4
Mn content in liver0.10.10.2-0.3-0.20.2-0.2-0.2-0.1-0.1-0.30.20.3-0.3-0.5
Na content in liver0.91.02.21.10.9-1.20.51.0-1.50.90.8-1.4-0.60.90.4
Rb content in liver0.91.11.7-1.0-0.91.1-1.1-1.0-1.0-1.0-1.20.61.2-1.1-1.3
Se content in liver0.10.10.30.20.3-0.20.10.2-0.60.30.0-0.6-0.10.20.1
Sr content in liver0.50.51.7-0.6-0.50.8-0.2-0.61.3-0.5-0.21.30.3-0.6-0.4
Zn content in liver0.91.01.51.21.1-1.11.01.10.30.91.0-1.1-1.11.01.0
Bone: minimum diameter5.610.513.53.33.4-3.43.33.30.63.73.2-3.4-3.33.53.3
Time in familiar zone, hab. session 10.40.41.50.40.5-0.60.90.51.20.30.6-0.2-0.70.40.7
Time in novel zone, hab. session 11.41.34.7-0.8-1.00.8-1.5-0.9-2.2-0.7-1.10.41.3-0.8-1.4
Total zone transitions, hab. session 10.20.30.50.70.5-0.70.40.6-0.10.60.6-0.0-0.50.60.2
Total locomotion distance, hab. session 12.12.93.91.81.8-1.72.01.81.41.61.7-1.2-2.01.61.9
Locomotion velocity, hab. session 11.92.73.91.71.6-1.52.01.61.81.41.6-1.0-1.91.41.9
Time in familiar zone, hab. session 20.00.00.2-0.1-0.2-0.1-0.2-0.10.2-0.4-0.10.00.1-0.10.1
Time in novel zone, hab. session 20.30.32.2-0.3-0.20.4-0.5-0.3-1.50.2-0.4-0.10.6-0.2-0.8
Total zone transitions, hab. session 20.10.10.80.20.1-0.20.20.10.90.10.30.5-0.20.10.1
Total locomotion distance, hab. session 20.81.01.81.01.0-0.91.20.91.40.91.0-0.7-1.10.91.1
Locomotion velocity, hab. session 20.91.22.31.01.0-0.91.30.91.50.81.1-0.7-1.20.91.2
Novel to familiar place preference ratio0.30.32.40.30.2-0.3-0.20.2-1.60.3-0.1-0.70.10.1-0.1
Novelty place preference0.40.43.5-0.0-0.1-0.1-0.5-0.0-1.90.0-0.4-0.50.4-0.1-0.4
Time in novel zone, NPP test0.40.44.00.20.1-0.3-0.40.2-2.00.3-0.2-0.80.20.1-0.3
Total zone transitions, NPP test0.00.00.10.30.1-0.30.00.2-0.30.20.20.1-0.10.1-0.2
Total locomotion distance, NPP test0.30.41.30.60.6-0.50.80.61.10.50.7-0.1-0.80.50.7
Locomotion velocity, NPP test0.10.21.50.30.2-0.20.50.21.20.10.30.3-0.50.20.4
Intraocular pressure0.70.91.5-1.2-1.10.9-1.1-1.0-0.8-0.8-1.00.81.1-0.7-0.9
Delta distance traveled before/after self-admin0.40.40.90.70.7-0.50.90.70.50.50.8-0.3-0.80.60.7
Delta ambulatory time before/after self-admin0.10.10.30.40.4-0.20.60.40.50.20.4-0.1-0.50.30.4
Parametrial fat weight1.63.05.01.81.8-2.01.51.9-1.11.61.5-2.2-1.71.81.8
Pavlov. Cond. lever latency0.60.81.4-0.9-1.00.9-0.6-0.90.8-1.2-0.80.90.7-0.9-0.4
Pavlov. Cond. magazine entry latency0.10.11.00.30.2-0.20.30.21.00.20.40.1-0.30.30.2
Pavlov. Cond. change in total contacts0.10.10.30.10.2-0.2-0.10.2-0.50.40.1-0.3-0.00.3-0.0
Pavlov. Cond. index score0.10.20.40.50.5-0.50.20.5-0.40.60.5-0.4-0.30.50.1
Pavlov. Cond. latency score0.20.30.60.60.6-0.60.30.6-0.30.80.6-0.4-0.40.60.1
Pavlov. Cond. lever contacts0.70.81.51.01.0-1.00.71.0-0.71.20.9-0.9-0.71.00.5
Pavlov. Cond. magazine entry number0.10.10.20.30.3-0.30.40.30.00.10.2-0.3-0.40.10.5
Pavlov. Cond. intertrial magazine entries0.30.41.80.50.6-0.60.20.6-1.30.60.3-0.8-0.30.4-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.60.6-0.60.40.6-0.30.70.5-0.7-0.40.60.3
Pavlov. Cond. response bias0.30.30.50.70.6-0.60.40.6-0.20.70.6-0.6-0.50.70.4
Pavlov. Cond. lever latency0.20.32.00.30.4-0.4-0.10.3-1.40.40.1-0.8-0.00.2-0.1
Pavlov. Cond. magazine entry latency0.70.91.4-1.0-1.11.0-0.6-1.01.0-1.0-0.81.20.7-0.9-0.5
Pavlov. Cond. change in total contacts0.50.72.5-0.7-0.80.8-0.3-0.71.6-0.7-0.51.30.4-0.7-0.4
Pavlov. Cond. index score0.70.93.3-0.9-0.90.9-0.3-0.81.8-0.9-0.61.40.5-0.8-0.3
Pavlov. Cond. latency score1.01.33.6-1.1-1.11.1-0.6-1.11.9-1.1-0.81.70.7-0.9-0.6
Pavlov. Cond. lever contacts0.20.33.1-0.1-0.20.20.3-0.11.8-0.20.10.7-0.2-0.10.2
Pavlov. Cond. magazine entry number1.31.62.61.41.4-1.50.81.4-1.51.31.1-1.6-1.01.30.7
Pavlov. Cond. intertrial magazine entries1.62.13.71.51.6-1.71.11.6-1.21.51.3-1.9-1.31.41.2
Pavlov. Cond. lever-magazine prob. diff.0.60.83.2-0.8-0.80.8-0.3-0.81.8-0.8-0.51.30.4-0.7-0.3
Pavlov. Cond. response bias0.60.83.4-0.7-0.80.8-0.2-0.71.8-0.8-0.51.30.4-0.7-0.3
Time in closed arm before self-admin0.70.81.41.00.9-0.91.21.00.20.70.8-0.9-1.00.71.0
Time in closed arm after self-admin0.20.20.5-0.6-0.40.40.0-0.50.7-0.3-0.40.60.3-0.3-0.1
Time in open arm before self-admin0.91.01.9-1.1-1.01.3-0.7-1.20.9-0.7-0.91.40.9-0.9-0.8
Time in open arm after self-admin1.01.12.11.21.2-1.10.81.3-0.50.91.0-1.4-1.01.00.9
Bone: periosteal estimation0.81.72.61.31.4-1.31.41.20.41.61.3-1.4-1.31.41.2
Bone: periosteal perimeter0.40.71.10.90.9-0.70.90.70.61.10.9-0.8-0.80.90.7
Bone: post-yield work0.20.30.80.40.5-0.60.50.5-0.60.70.4-0.9-0.40.60.5
Progressive ratio test 1 active lever presses0.10.10.2-0.4-0.2-0.0-0.3-0.1-0.0-0.1-0.30.50.2-0.1-0.3
Progressive ratio test 1 breakpoint0.10.10.4-0.5-0.30.2-0.4-0.30.1-0.2-0.30.60.3-0.2-0.4
Progressive ratio test 1 inactive lever presses2.32.53.81.71.7-1.91.41.70.31.61.6-1.6-1.61.81.4
Progressive ratio test 2 active lever presses0.00.00.10.10.2-0.20.10.2-0.10.20.2-0.1-0.10.2-0.1
Progressive ratio test 2 breakpoint0.00.00.00.00.1-0.10.00.1-0.20.10.0-0.10.00.1-0.2
Progressive ratio test 2 inactive lever presses0.91.01.71.11.0-1.31.01.20.70.91.2-0.5-1.01.10.7
Incentive Sensitization - Responses0.00.00.1-0.2-0.10.2-0.1-0.2-0.1-0.2-0.10.10.2-0.2-0.4
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.00.10.0-0.10.1-0.1-0.00.10.1-0.1-0.3
Sum of active levers in priming session hrs 5-60.90.91.50.90.8-0.90.91.01.20.71.1-0.8-1.01.01.0
Progressive ratio0.50.61.5-0.6-0.71.0-0.4-0.70.7-0.8-0.61.20.5-0.9-0.5
Food seeking constrained by brief footshock0.10.10.2-0.3-0.30.4-0.4-0.3-0.1-0.1-0.40.20.1-0.20.1
Seeking ratio, punishment vs. effort0.50.61.60.70.7-1.00.30.7-0.80.90.5-1.3-0.60.90.7
Retroperitoneal fat weight0.31.06.30.70.8-0.90.20.8-2.50.90.4-1.3-0.20.80.0
Reaction time number correct0.10.20.8-0.3-0.20.5-0.2-0.30.50.10.10.90.3-0.1-0.6
Reaction time mean minus median0.60.72.0-0.9-0.90.6-1.0-0.8-1.4-0.8-1.00.10.8-0.8-0.5
Reaction time mean minus median AUC0.81.05.0-0.8-0.80.6-1.1-0.6-2.2-0.6-1.0-0.01.0-0.7-0.8
Reaction time num false alarms0.30.42.40.40.4-0.6-0.20.3-1.50.60.3-1.00.00.6-0.1
Reaction time num false alarms AUC0.20.32.70.10.1-0.2-0.5-0.0-1.60.2-0.0-0.70.30.2-0.4
Reaction time trials correct on left0.10.20.8-0.3-0.20.5-0.2-0.30.50.10.10.90.3-0.1-0.6
Reaction time trials on left0.10.20.9-0.3-0.20.6-0.3-0.30.50.00.00.90.4-0.2-0.6
Reaction time mean0.60.91.6-1.2-0.90.8-1.0-0.7-1.3-0.9-1.20.20.9-1.0-0.6
Reaction time mean AUC0.50.71.9-1.0-0.80.6-0.9-0.6-1.4-0.8-1.1-0.00.8-0.8-0.5
Median of all reaction times0.60.81.3-1.1-0.90.7-0.9-0.7-1.1-0.9-1.10.20.8-1.0-0.6
Reaction time omissions1.52.03.0-1.5-1.51.5-1.6-1.5-0.6-1.4-1.31.71.5-1.3-1.4
Reaction time false alarm rate0.30.42.80.20.1-0.5-0.30.1-1.70.1-0.1-1.10.10.30.0
Reaction time premature initiation rate0.20.20.60.50.4-0.40.20.5-0.60.40.3-0.8-0.30.40.1
Reaction time premature initiations0.10.20.30.40.4-0.30.10.5-0.60.60.5-0.5-0.20.5-0.1
Std. dev. reaction times0.40.61.6-0.9-0.70.6-0.8-0.6-1.2-0.7-0.90.00.7-0.7-0.3
Reaction time trials completed0.10.20.9-0.3-0.20.6-0.3-0.30.50.00.00.90.4-0.2-0.6
Reaction time trials AUC0.20.20.9-0.5-0.30.6-0.4-0.40.2-0.0-0.10.90.5-0.3-0.7
Run reversals in cocaine runway, females3.23.14.21.92.0-1.62.01.80.82.01.7-1.3-1.91.81.8
Run reversals in cocaine runway, males0.30.30.9-0.4-0.40.5-0.2-0.50.2-0.5-0.30.90.5-0.5-0.7
Latency to leave start box in cocaine runway2.62.83.81.91.7-1.91.52.0-0.21.61.8-1.6-1.81.71.7
Latency to leave start box in cocaine runway, F4.14.56.02.42.2-2.42.02.4-0.42.22.1-2.1-2.22.22.1
Latency to leave start box in cocaine runway, M0.10.10.3-0.4-0.40.4-0.3-0.30.4-0.5-0.20.40.2-0.4-0.2
Std. dev. time between licks in bursts1.11.32.0-1.4-1.21.1-0.9-1.20.5-1.2-1.21.41.0-1.3-1.0
Total sessions with >9 infusions1.61.83.4-1.4-1.41.5-1.0-1.40.8-1.4-1.11.81.2-1.4-1.1
Short access day 1 total inactive lever presses1.21.43.11.21.1-1.21.31.11.80.91.3-0.3-1.21.11.0
Short access day 10 total inactive lever presses1.31.42.01.21.2-1.21.21.11.41.11.4-0.8-1.31.21.2
Short access day 1 total infusions0.10.10.40.30.2-0.60.20.3-0.00.30.3-0.1-0.30.30.3
Short access day 10 total infusions0.10.10.3-0.2-0.30.1-0.4-0.10.6-0.5-0.10.10.1-0.1-0.1
Short access total infusions0.30.30.5-0.6-0.60.4-0.7-0.50.1-0.7-0.40.70.5-0.5-0.5
Short access day 1 locomotion0.00.00.1-0.4-0.20.2-0.1-0.20.1-0.2-0.3-0.10.1-0.1-0.0
Short access day 10 total locomotion0.20.20.8-0.5-0.40.4-0.5-0.4-0.9-0.4-0.40.30.4-0.3-0.3
Short access total locomotion0.40.40.6-0.8-0.70.7-0.8-0.6-0.2-0.7-0.70.80.7-0.6-0.6
One hour access (0.3 mA shock)0.20.20.50.50.3-0.30.50.40.70.30.5-0.1-0.40.30.4
Compulsive drug intake0.30.30.70.50.3-0.7-0.00.4-0.90.20.3-0.9-0.40.20.7
One hour access (shock baseline)0.00.10.2-0.10.10.20.00.10.40.00.10.40.10.2-0.4
Social response proportion1.51.72.71.61.4-1.50.91.6-1.01.21.5-1.3-1.21.21.0
Social responses0.50.61.21.01.0-0.80.70.9-0.50.91.1-0.6-0.60.80.2
Social time0.81.11.71.11.1-1.10.91.2-0.51.01.1-1.3-1.01.10.9
Soleus weight0.30.93.5-1.0-0.90.9-0.4-1.01.9-0.9-0.51.20.5-0.8-0.3
Bone: stiffness1.01.53.51.21.3-1.30.91.2-1.21.61.0-1.9-0.91.30.8
Tibialis anterior weight4.114.218.2-4.3-4.13.9-4.1-4.1-1.5-3.6-3.93.54.0-3.7-3.6
Time to tail flick, vehicle, before self-admin0.50.50.70.80.6-0.80.70.70.50.80.7-0.7-0.60.70.6
Time to tail flick, vehicle, after self-admin1.01.14.10.90.9-0.61.40.72.01.01.10.1-1.00.90.9
Time to tail flick, test, before self-admin0.00.00.10.20.1-0.00.30.10.10.10.0-0.1-0.20.00.2
Time to tail flick, test, after self-admin2.12.23.01.51.6-1.41.71.6-0.11.71.4-1.6-1.51.61.4
Delta time to tail flick, vehicle, before/after SA0.10.10.30.40.5-0.10.50.30.30.50.50.0-0.40.50.2
Delta time to tail flick, test, before/after SA1.11.01.51.01.0-1.00.81.1-0.61.21.0-1.2-0.81.20.8
Tibia length0.10.30.70.60.6-0.50.40.5-0.50.80.5-0.8-0.40.60.3
Ambulatory time before self-admin0.50.60.70.90.9-0.80.90.7-0.10.90.8-0.7-0.70.80.7
Ambulatory time after self-admin3.03.34.12.01.9-1.82.01.81.61.82.0-1.3-1.91.71.8
Bone: tissue strength0.90.91.11.01.1-0.90.91.0-0.21.00.9-1.0-0.91.00.9
Total heroin consumption1.61.92.61.51.5-1.61.61.30.61.41.4-1.2-1.41.31.4
Bone: trabecular number0.10.20.5-0.4-0.40.4-0.5-0.4-0.7-0.5-0.6-0.10.4-0.5-0.4
Bone: trabecular spacing0.20.31.8-0.2-0.20.1-0.6-0.1-1.30.0-0.30.00.5-0.2-0.6
Bone: trabecular thickness0.20.20.60.40.4-0.30.60.40.80.20.4-0.2-0.50.30.5
Bone: trabecular tissue density0.40.51.4-0.7-0.70.5-0.9-0.7-1.2-0.5-0.8-0.10.8-0.6-0.7
Water consumed over 24 hours1.72.02.71.61.5-1.51.51.50.61.51.7-1.0-1.41.51.2
Number of responses in last shaping day0.40.40.7-0.8-0.70.5-0.8-0.6-0.3-0.7-0.70.40.7-0.7-0.6