Hub : Genes

Ugt2b15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr14_20718303_20719756 0.56 0.12 0.0e+00 0.47 0.44 0.48 0.48 8.4e-59 2.9e-53 9.5e-60 1.6e-59
2 Liver intron excision ratio chr14_20768768_20770242 0.2 0.12 1.1e-16 0.13 0.11 0.11 0.12 2.0e-14 3.3e-12 4.3e-12 1.3e-13
3 Liver intron excision ratio chr14_20818050_20819532 0.59 0.14 0.0e+00 0.38 0.38 0.42 0.43 1.5e-44 4.1e-45 2.9e-51 9.9e-52
4 Liver mRNA stability Ugt2b15 0.28 0.14 0.0e+00 0.07 0.21 0.17 0.21 2.3e-08 9.7e-23 1.1e-18 6.1e-23
5 Liver intron excision ratio chr14_20820793_20828959 0.87 0.05 0.0e+00 0.56 0.51 0.62 0.62 8.7e-76 6.2e-65 2.5e-87 1.4e-87
6 Liver gene expression Ugt2b15 0.5 0.16 0.0e+00 0.15 0.12 0.15 0.04 3.9e-16 6.4e-13 5.1e-16 4.1e-05
7 Liver intron excision ratio chr14_20721564_20779363 0.15 0.09 6.0e-14 0.07 0.1 0.1 0.09 2.8e-08 6.1e-11 9.3e-11 1.8e-10
8 Liver intron excision ratio chr14_20721564_20757388 0.78 0.1 0.0e+00 0.48 0.42 0.5 0.49 2.1e-60 8.0e-51 1.8e-63 1.6e-62
9 Liver intron excision ratio chr14_20771925_20779363 0.9 0.02 0.0e+00 0.5 0.45 0.56 0.56 1.8e-64 7.8e-55 1.9e-74 5.5e-74
10 Liver intron excision ratio chr14_20721564_20733031 0.85 0.04 0.0e+00 0.42 0.35 0.44 0.42 3.2e-50 1.9e-40 1.5e-53 8.1e-51
11 Liver intron excision ratio chr14_20718303_20770242 0.84 0.04 0.0e+00 0.54 0.45 0.56 0.55 1.6e-70 2.4e-55 1.2e-74 2.4e-73
12 Liver intron excision ratio chr14_20768768_20819532 0.03 0.03 7.5e-03 0.01 0.01 0.02 0 8.9e-03 3.1e-02 1.8e-03 8.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.30.5-0.60.7-0.60.5-0.60.50.2-0.60.5-0.5-0.6-0.0
Area under the delay curve0.10.10.4-0.10.1-0.20.5-0.0-0.00.6-0.20.3-0.3-0.40.2
BMI with tail1.54.88.7-2.22.1-2.12.7-2.01.63.0-2.42.4-2.0-2.40.4
BMI without tail0.20.42.4-0.10.10.10.8-0.0-0.41.6-0.30.5-0.0-0.71.0
Body weight0.20.83.3-0.70.6-0.61.3-0.60.11.8-0.91.0-0.6-1.10.0
Weight adjusted by age1.21.31.9-1.31.4-1.30.8-1.31.40.2-1.21.2-1.3-1.2-0.5
Bone surface0.10.20.9-0.20.3-0.1-0.2-0.30.5-0.80.00.0-0.0-0.2-0.9
Bone volume0.10.10.40.4-0.20.3-0.50.3-0.2-0.60.4-0.30.30.2-0.3
Breakpoint value in progressive ratio session0.20.21.00.4-0.40.2-0.30.4-0.90.10.3-0.30.20.2-1.0
Number of licking bursts0.20.21.0-0.30.3-0.30.2-0.40.40.1-0.40.4-0.5-0.6-1.0
Context. condit. distance diff. score0.60.74.10.5-0.20.4-1.00.40.3-2.00.7-0.80.60.90.6
Locomotion velocity, session 11.01.13.1-0.90.6-1.01.2-0.80.51.8-1.11.1-1.0-1.2-0.2
Locomotion distance, session 10.20.30.70.5-0.60.6-0.80.5-0.4-0.60.5-0.60.50.4-0.5
Locomotion velocity, session 20.10.20.40.3-0.30.3-0.50.3-0.4-0.50.2-0.40.30.4-0.7
Locomotion distance, session 20.20.20.90.4-0.40.5-0.50.4-0.4-0.30.4-0.40.30.2-1.0
Locomotion velocity, session 30.60.61.00.8-0.80.8-1.00.9-0.5-0.70.8-0.80.70.80.9
Locomotion distance, session 30.20.22.6-0.0-0.1-0.0-0.30.10.3-0.30.1-0.00.0-0.11.6
Stereotopy head waving bouts, day 30.70.81.3-0.90.9-0.81.0-0.90.51.1-1.11.0-1.1-1.00.0
Stereotopy head waving duration, day 30.20.21.0-0.20.3-0.30.4-0.30.10.5-0.50.3-0.5-0.3-1.0
Locomotion velocity, session 71.81.92.71.6-1.61.7-1.31.6-1.6-0.61.5-1.41.51.1-0.4
Locomotion distance, session 71.21.52.11.4-1.31.4-1.41.3-0.9-1.11.4-1.21.31.0-0.8
Stereotopy head waving bouts, day 70.20.30.5-0.60.7-0.50.3-0.60.70.2-0.50.5-0.6-0.40.3
Stereotopy head waving duration, day 70.40.51.2-0.70.6-0.60.7-0.60.31.1-0.70.7-0.7-0.70.3
Locomotion velocity, session 80.10.10.60.10.0-0.0-0.4-0.00.2-0.80.0-0.30.00.5-0.6
Locomotion distance, session 81.11.65.31.1-0.81.1-1.71.0-0.3-2.31.2-1.41.01.3-0.8
Degree of sensitization distance1.31.32.01.3-1.11.4-1.01.1-0.9-0.91.3-1.11.21.0-1.3
Degree of sensitization stereotypy0.10.10.9-0.30.3-0.1-0.1-0.20.4-0.10.00.1-0.1-0.00.9
Conditioned locomotion0.50.61.6-0.71.0-0.70.5-0.81.30.0-0.60.7-0.7-0.90.3
Cocaine response after cond. corrected0.70.71.10.9-1.10.9-1.00.9-0.9-0.70.9-0.80.90.7-0.6
Cocaine response after cond. not corrected0.80.81.30.9-1.00.9-1.10.9-0.8-1.10.9-0.90.90.8-0.7
Cocaine response before conditioning0.10.10.2-0.20.5-0.20.0-0.30.5-0.3-0.30.1-0.3-0.1-0.1
Saline control response0.70.91.31.0-1.01.1-1.11.0-0.8-0.81.0-1.01.11.10.0
Bone: connectivity density0.40.71.0-0.90.9-1.00.9-0.90.50.7-0.90.8-0.8-0.8-0.5
Bone: cortical apparent density0.30.43.10.1-0.2-0.10.90.2-0.91.8-0.30.1-0.10.10.3
Bone: cortical area0.30.41.00.7-0.61.0-0.40.6-0.70.10.7-0.50.80.6-0.5
Bone: cortical porosity1.61.73.6-1.51.5-1.61.0-1.51.90.4-1.41.2-1.4-1.1-0.6
Bone: cortical porosity2.62.94.5-1.91.9-1.91.5-1.92.11.0-1.81.7-1.8-1.5-0.3
Bone: cortical thickness0.30.50.8-0.70.8-0.40.8-0.80.70.9-0.70.8-0.6-0.60.2
Bone: cortical thickness0.30.31.10.3-0.10.5-0.70.30.2-1.00.5-0.50.30.71.0
Bone: cortical tissue density0.30.43.3-0.0-0.1-0.21.00.1-0.81.8-0.40.3-0.2-0.10.4
Condit. Reinf. active minus inactive responses0.70.81.2-0.90.8-0.81.1-0.90.61.1-0.91.0-0.7-1.10.4
Condit. Reinf. active-inactive response ratio2.72.93.8-1.91.9-1.81.8-2.01.81.2-1.81.8-1.7-1.70.2
Condit. Reinf. active responses0.00.00.20.1-0.30.2-0.10.2-0.40.20.1-0.00.2-0.10.1
Condit. Reinf. inactive responses2.12.53.31.8-1.81.7-1.81.8-1.8-1.11.7-1.61.71.4-0.0
Incentive salience index mean0.10.10.3-0.30.2-0.20.4-0.30.10.6-0.20.4-0.1-0.4-0.4
Condit. Reinf. lever presses0.10.11.00.1-0.10.1-0.20.1-0.1-0.20.2-0.10.10.0-1.0
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.30.2-0.30.3-0.4-0.10.1-0.30.10.2-0.5
Condit. Reinf. active-inactive response ratio0.10.10.20.4-0.50.5-0.40.4-0.5-0.00.4-0.30.40.20.3
Condit. Reinf. active responses0.20.20.70.5-0.30.3-0.60.4-0.4-0.50.3-0.50.20.5-0.8
Condit. Reinf. inactive responses0.50.61.20.7-0.50.6-0.90.7-0.5-1.10.6-0.90.60.9-0.9
Condit. Reinf. lever presses0.60.82.10.8-0.60.9-1.20.8-0.3-1.41.0-1.00.91.00.4
Condit. Reinf. lever reinforcers received0.20.30.70.5-0.30.4-0.80.5-0.3-0.90.4-0.70.30.6-0.7
Conditioned reinforcement - actives0.20.20.7-0.30.5-0.30.1-0.40.8-0.3-0.20.4-0.3-0.50.1
Conditioned reinforcement - inactives1.21.31.91.1-1.31.2-1.41.2-0.8-1.21.3-1.21.31.20.4
Conditioned locomotion0.00.00.20.10.00.1-0.20.10.2-0.50.2-0.10.20.10.3
Patch foraging indifference point 0 sec0.40.60.90.8-0.70.6-0.60.7-1.0-0.40.5-0.90.61.0-1.0
Patch foraging indifference point AUC2.12.44.41.8-1.91.8-1.31.8-2.1-0.41.8-1.31.71.0-0.0
Delay disc. indifference point, 0s delay0.20.20.6-0.40.3-0.40.6-0.30.10.8-0.40.5-0.4-0.6-0.7
Delay disc. indifference point, 16s delay1.01.02.7-0.80.8-0.71.3-0.60.41.6-0.91.1-0.9-1.11.1
Delay disc. indifference point, 2s delay2.32.63.31.8-1.81.7-1.51.8-1.7-1.01.7-1.61.71.4-1.4
Delay disc. indifference point, 24s delay0.20.20.4-0.30.5-0.50.5-0.30.60.2-0.40.3-0.5-0.50.4
Delay disc. indifference point, 4s delay0.20.20.80.5-0.60.40.00.6-0.90.60.4-0.30.50.3-0.2
Delay disc. indifference point, 8s delay1.61.62.3-1.21.2-1.31.5-1.10.91.5-1.41.4-1.3-1.50.6
Indifference point function ln k0.70.91.5-1.21.2-1.00.8-1.21.20.2-1.10.9-1.0-0.60.2
Indifference point function log k0.70.91.5-1.21.2-1.00.8-1.21.20.2-1.10.9-1.0-0.60.2
Patch foraging total patch changes 0 sec0.30.51.00.8-0.70.7-0.50.8-1.0-0.40.5-0.90.71.0-0.6
Patch foraging total patch changes 12 sec0.20.31.00.8-0.50.6-0.00.7-1.00.50.5-0.30.50.2-0.1
Patch foraging total patch changes 18 sec0.10.10.60.4-0.50.2-0.10.4-0.80.20.3-0.20.30.1-0.4
Patch foraging total patch changes 24 sec0.70.91.51.1-1.21.0-1.01.2-0.9-0.71.0-1.01.00.60.4
Patch foraging total patch changes 6 sec1.01.52.31.5-1.31.5-1.01.5-1.5-0.51.3-1.31.31.1-0.4
Patch foraging time to switch 0 sec3.35.16.5-2.52.4-2.52.5-2.42.02.0-2.52.3-2.4-2.1-0.3
Patch foraging water rate 0 sec1.42.23.71.8-1.41.9-1.51.7-1.2-1.21.7-1.51.61.30.0
Patch foraging water rate 12 sec0.50.81.80.8-0.61.0-1.10.70.0-1.31.0-0.90.91.00.4
Patch foraging water rate 18 sec2.02.74.11.7-1.41.8-1.91.7-0.8-2.01.7-1.91.61.9-0.1
Patch foraging water rate 24 sec1.41.95.51.4-0.81.5-1.71.2-0.3-2.31.5-1.51.31.40.2
Patch foraging water rate 6 sec0.60.81.71.0-0.91.3-0.91.0-0.5-0.71.2-0.91.20.80.0
Seeking ratio, delayed vs. immediate footshock1.11.32.31.0-1.31.0-1.51.1-1.0-1.31.1-1.21.11.20.0
Distance traveled before self-admin0.50.62.10.7-0.80.8-0.70.6-0.4-0.60.7-0.60.60.6-1.4
Distance traveled after self-admin3.03.35.81.8-1.71.8-2.21.7-1.2-2.42.0-1.91.71.8-1.3
Extensor digitorum longus weight9.738.146.8-6.86.8-6.86.2-6.86.64.3-6.56.6-6.6-6.31.6
Bone: elastic displacement0.40.51.7-0.70.8-0.80.0-0.71.3-0.8-0.50.4-0.6-0.3-0.2
Bone: elastic work0.20.30.9-0.50.5-0.7-0.3-0.50.9-0.9-0.30.1-0.30.2-0.2
Bone: endosteal estimation1.73.84.42.1-1.92.0-2.11.9-1.7-1.92.0-2.12.01.9-1.6
Bone: endosteal perimeter0.51.12.71.0-0.91.0-1.10.8-0.8-1.11.0-1.01.00.8-1.7
Epididymis fat weight0.10.31.5-0.20.2-0.30.7-0.10.01.2-0.40.5-0.2-0.70.2
Delta time in closed arm before/after self-admin1.31.21.6-1.10.9-1.01.3-1.20.81.2-1.11.3-1.0-1.11.1
Delta time in open arm before/after self-admin1.11.11.91.2-1.21.0-0.91.4-1.3-0.51.0-1.21.01.10.2
Diff in mean of infusions in LGA sessions0.00.00.2-0.20.3-0.2-0.0-0.10.0-0.2-0.10.1-0.2-0.1-0.4
Delay discount exponential model param0.00.00.2-0.10.10.0-0.3-0.20.2-0.50.0-0.10.10.1-0.2
Extinction: sum of active levers before priming0.70.71.20.8-0.80.6-1.10.8-0.6-1.00.8-0.90.50.81.1
Active lever presses in extinction session 60.60.61.10.9-0.90.6-0.90.8-1.1-0.60.7-0.70.60.4-0.5
Bone: final force0.10.10.70.4-0.20.6-0.20.2-0.30.10.2-0.20.30.3-0.8
Bone: final moment0.10.10.30.4-0.20.6-0.20.3-0.30.10.3-0.20.40.3-0.4
Food consumed during 24 hour testing period2.42.95.51.7-1.71.7-2.31.7-0.9-2.32.0-1.81.71.40.0
Glucose1.01.52.01.4-1.31.3-1.21.3-1.2-1.11.4-1.31.21.2-0.5
Heart weight0.40.61.0-0.71.0-0.60.9-0.90.80.6-0.70.8-0.7-0.8-0.4
Delay discount hyperbolic model param0.10.10.2-0.40.4-0.3-0.0-0.50.5-0.3-0.30.2-0.3-0.1-0.0
Intermittent access intake day 1-15 change1.31.33.2-1.21.5-1.00.7-1.21.8-0.2-0.81.2-1.1-1.4-0.3
Intermittent access intake escalation0.70.71.8-0.81.0-0.70.3-0.81.3-0.5-0.40.8-0.7-1.0-0.9
Intermittent access intake escalation 20.10.10.50.20.10.3-0.30.10.2-0.70.3-0.00.2-0.2-0.2
Intermitt. access day 1 inactive lever presses1.01.11.61.1-1.30.9-1.21.1-1.1-1.11.1-1.11.10.90.3
Intermitt. access day 15 inactive lever presses1.51.72.31.3-1.51.3-1.41.3-1.0-1.31.4-1.41.21.21.2
Intermitt. access escalation Index1.00.91.6-1.11.0-1.10.6-1.11.30.3-0.90.9-1.1-1.0-0.2
Intermittent access day 1 total infusions0.20.22.50.1-0.1-0.1-0.30.20.3-0.30.1-0.20.00.21.6
Intermittent access day 15 total infusions0.10.10.8-0.00.1-0.0-0.40.00.7-0.90.3-0.10.0-0.20.4
Intermittent access terminal intake (last 3 days)0.30.31.20.5-0.30.5-0.70.50.2-1.10.7-0.40.50.10.5
Intermittent access total infusions0.10.21.20.1-0.00.1-0.30.20.3-0.50.2-0.10.20.01.1
Intermittent access day 1 locomotion0.10.10.50.2-0.10.0-0.30.20.0-0.20.1-0.30.20.30.7
Intermittent access day 15 total locomotion0.00.00.20.20.20.0-0.10.10.3-0.40.1-0.20.10.10.1
Intermittent access total locomotion0.10.10.2-0.20.4-0.30.4-0.30.40.2-0.30.2-0.2-0.20.4
Intermittent access standard deviation0.20.20.70.4-0.20.5-0.50.4-0.0-0.80.6-0.40.50.30.2
Left kidney weight0.30.71.30.9-0.61.2-0.90.8-0.3-1.10.9-0.80.90.70.9
Right kidney weight0.30.91.71.1-1.01.3-0.61.1-1.0-0.10.9-0.91.10.80.5
Cocaine induced anxiety0.10.10.2-0.20.3-0.20.3-0.20.20.4-0.30.3-0.2-0.3-0.2
Post-drug Anxiety0.20.20.90.1-0.20.20.30.2-0.50.9-0.00.10.1-0.10.9
Baseline Anxiety0.20.21.00.1-0.30.3-0.40.2-0.1-0.60.4-0.30.20.51.0
Tail length0.10.41.80.5-0.40.7-0.60.5-0.5-0.60.6-0.40.50.21.4
Length with tail0.62.12.91.6-1.61.7-1.51.6-1.5-1.11.6-1.51.51.3-0.2
Length without tail0.30.81.80.8-1.10.7-0.60.8-0.9-0.40.7-0.90.81.0-1.3
Times rat made contact with spout0.20.20.50.3-0.60.4-0.30.5-0.70.10.5-0.20.40.10.6
Lifetime Intake0.10.11.0-0.10.1-0.2-0.2-0.10.4-0.30.10.1-0.0-0.11.0
Liver weight, left1.52.33.61.8-1.81.6-1.41.9-1.8-0.41.6-1.61.51.3-1.0
Liver weight, right2.43.95.62.2-2.41.9-1.82.2-2.3-1.02.0-2.01.91.8-2.1
Locomotor activity0.40.72.10.9-0.80.7-1.00.8-0.1-1.50.8-0.90.70.7-0.1
Locomotor testing distance0.30.63.50.5-0.10.4-1.00.40.4-1.90.4-0.70.40.60.6
Locomotor testing rearing0.20.42.20.10.40.2-0.60.00.6-1.50.2-0.30.00.31.0
Locomotion in novel chamber0.00.00.30.0-0.20.10.10.1-0.00.20.20.10.0-0.20.5
Locomotion in novel chamber post-restriction0.70.81.50.9-1.11.2-0.61.0-1.20.10.8-0.70.90.80.9
Fecal boli incidents, locomotor time 11.11.22.7-1.31.4-1.00.9-1.21.60.2-1.01.0-1.1-0.61.1
Change in fecal boli incidents, locomotor task0.10.10.5-0.20.2-0.60.1-0.20.2-0.0-0.40.1-0.5-0.3-0.7
Time >=10cm from walls, locomotor time 11.51.52.3-1.51.4-1.41.0-1.31.20.5-1.21.3-1.4-1.20.9
Bouts of movement, locomotor time 10.91.01.3-1.01.0-0.81.2-1.00.91.1-1.11.0-1.0-1.00.2
Total resting periods, locomotor time 10.60.71.1-0.90.8-0.81.0-0.80.81.0-1.00.9-0.8-0.9-0.3
Rest time, locomotor task time 10.80.92.60.7-0.80.7-1.30.7-0.2-1.60.8-1.00.71.0-0.7
Distance moved, locomotor task time 10.20.20.4-0.40.4-0.40.5-0.30.20.5-0.30.5-0.3-0.6-0.1
Vertical activity count, locomotor time 10.40.41.80.4-0.40.50.50.4-1.11.30.20.20.3-0.50.5
Time >=10cm from walls, locomotor time 20.20.30.6-0.60.5-0.7-0.1-0.30.7-0.6-0.30.2-0.6-0.30.6
Bouts of movement, locomotor time 20.10.20.70.3-0.50.2-0.30.3-0.4-0.20.1-0.40.20.5-0.9
Total resting periods, locomotor time 20.10.11.20.2-0.40.1-0.20.2-0.3-0.0-0.1-0.20.10.3-1.1
Rest time, locomotor task time 20.80.93.30.6-0.70.5-1.30.70.0-1.80.7-1.10.51.1-1.3
Distance moved, locomotor task time 21.21.42.4-1.21.2-1.21.4-1.20.71.4-1.21.4-1.0-1.50.1
Vertical activity count, locomotor time 20.30.31.6-0.10.10.10.7-0.0-0.81.3-0.10.50.1-0.60.7
Light reinforcement 10.51.01.41.2-1.01.1-0.91.1-1.1-0.61.1-0.91.10.7-0.9
Light reinforcement 20.10.10.4-0.20.1-0.30.1-0.1-0.00.3-0.30.1-0.3-0.10.7
Bone: marrow area1.73.64.22.0-1.92.0-2.11.9-1.6-1.92.0-2.02.01.9-1.6
Bone: maximum diameter0.10.10.70.1-0.00.30.4-0.0-0.40.8-0.10.20.1-0.3-0.7
Bone: maximum force0.30.60.90.8-0.61.0-0.70.6-0.7-0.50.7-0.70.80.9-0.7
Bone: maximum moment0.40.61.10.9-0.71.1-0.80.7-0.7-0.50.8-0.80.90.9-0.3
Mean time between licks in bursts4.46.17.6-2.72.6-2.42.8-2.72.22.4-2.82.6-2.6-2.31.3
Mean num. licks in bursts0.91.15.10.8-1.00.9-0.61.0-1.1-0.21.0-0.81.00.92.3
Cd content in liver1.51.72.2-1.41.3-1.51.5-1.51.01.3-1.41.4-1.3-1.20.5
Co content in liver0.10.10.30.3-0.50.1-0.20.2-0.40.00.0-0.30.20.40.1
Cu content in liver0.50.71.10.9-1.00.9-0.70.8-1.1-0.20.7-0.80.90.9-0.5
Fe content in liver0.60.82.6-0.80.5-0.91.3-0.7-0.11.6-1.00.9-0.7-0.7-0.2
K content in liver1.21.13.11.1-1.61.0-0.61.2-1.80.60.7-0.81.10.7-0.9
Mg content in liver0.90.92.81.1-1.41.1-0.41.1-1.70.80.7-0.61.00.4-0.3
Mn content in liver0.10.10.2-0.20.2-0.10.3-0.20.30.2-0.30.3-0.3-0.40.0
Na content in liver0.70.82.20.9-1.20.8-0.41.0-1.50.50.7-0.60.90.4-0.8
Rb content in liver1.01.21.9-0.91.1-1.11.4-1.00.81.3-1.21.2-1.1-1.30.7
Se content in liver0.00.10.20.3-0.20.30.00.2-0.50.30.0-0.10.20.1-0.2
Sr content in liver0.30.31.3-0.50.8-0.30.1-0.51.1-0.6-0.20.3-0.6-0.40.5
Zn content in liver0.91.01.31.1-1.10.8-1.11.1-1.0-0.80.9-1.10.90.9-1.0
Bone: minimum diameter5.39.913.63.4-3.43.7-3.13.3-3.2-2.13.3-3.33.53.3-1.4
Time in familiar zone, hab. session 10.40.41.20.5-0.60.2-0.90.5-0.3-1.10.6-0.70.40.7-0.5
Time in novel zone, hab. session 11.31.33.9-0.90.8-0.61.6-0.90.62.0-1.01.3-0.7-1.41.1
Total zone transitions, hab. session 10.20.30.60.5-0.70.7-0.70.6-0.6-0.50.6-0.50.60.2-0.5
Total locomotion distance, hab. session 12.13.04.31.8-1.71.6-2.01.8-1.4-2.11.7-2.01.61.9-0.9
Locomotion velocity, hab. session 11.92.74.71.6-1.51.5-2.01.6-1.2-2.21.5-1.91.41.9-0.9
Time in familiar zone, hab. session 20.00.00.2-0.2-0.1-0.4-0.1-0.20.2-0.1-0.10.1-0.10.10.1
Time in novel zone, hab. session 20.40.41.8-0.20.40.20.9-0.2-0.21.3-0.40.6-0.2-0.80.6
Total zone transitions, hab. session 20.10.10.50.1-0.20.2-0.60.10.2-0.70.3-0.20.10.10.1
Total locomotion distance, hab. session 20.81.01.91.0-0.90.9-1.30.9-0.6-1.41.0-1.10.91.2-0.4
Locomotion velocity, hab. session 20.81.12.31.0-0.90.9-1.40.9-0.6-1.51.0-1.20.91.3-0.6
Novel to familiar place preference ratio0.20.21.20.2-0.30.30.40.2-0.81.1-0.10.10.1-0.1-0.1
Novelty place preference0.30.32.2-0.1-0.10.00.7-0.0-0.61.5-0.40.4-0.1-0.40.2
Time in novel zone, NPP test0.30.32.20.1-0.30.20.60.2-0.81.5-0.20.20.1-0.30.3
Total zone transitions, NPP test0.00.00.10.1-0.30.2-0.30.2-0.2-0.00.2-0.10.1-0.2-0.3
Total locomotion distance, NPP test0.40.51.50.6-0.50.5-1.00.6-0.3-1.20.6-0.80.50.7-0.6
Locomotion velocity, NPP test0.20.21.10.2-0.20.2-0.70.20.1-1.10.3-0.50.20.4-0.6
Intraocular pressure0.71.01.6-1.10.9-1.01.3-1.00.41.2-1.11.1-0.7-0.90.9
Delta distance traveled before/after self-admin0.40.41.20.7-0.50.5-0.90.7-0.4-1.10.7-0.80.50.70.2
Delta ambulatory time before/after self-admin0.20.20.60.3-0.20.2-0.60.3-0.1-0.80.3-0.50.30.50.5
Parametrial fat weight1.42.75.61.8-2.01.5-1.21.9-2.4-0.21.5-1.71.71.8-0.9
Pavlov. Cond. lever latency0.60.71.5-1.00.9-1.20.7-1.01.10.1-0.90.7-0.9-0.40.5
Pavlov. Cond. magazine entry latency0.10.10.50.2-0.20.2-0.50.2-0.1-0.70.4-0.30.30.2-0.6
Pavlov. Cond. change in total contacts0.10.10.40.2-0.20.40.00.2-0.60.30.2-0.00.3-0.0-0.2
Pavlov. Cond. index score0.20.20.50.5-0.50.6-0.30.5-0.7-0.00.5-0.30.50.1-0.6
Pavlov. Cond. latency score0.30.30.70.6-0.60.8-0.50.6-0.7-0.10.7-0.40.60.1-0.5
Pavlov. Cond. lever contacts0.70.81.71.0-1.01.3-0.71.0-1.1-0.21.0-0.71.00.5-0.6
Pavlov. Cond. magazine entry number0.10.10.20.3-0.30.1-0.30.3-0.1-0.20.1-0.40.10.50.0
Pavlov. Cond. intertrial magazine entries0.20.30.70.7-0.60.7-0.10.6-0.90.60.3-0.30.4-0.1-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.00.6-0.60.7-0.50.6-0.8-0.20.6-0.40.60.3-1.0
Pavlov. Cond. response bias0.30.40.70.6-0.60.7-0.50.6-0.9-0.20.7-0.50.70.3-0.8
Pavlov. Cond. lever latency0.10.20.60.4-0.40.30.20.3-0.80.80.1-0.00.2-0.1-0.8
Pavlov. Cond. magazine entry latency0.60.71.9-1.11.0-0.90.5-1.01.4-0.2-0.90.7-0.9-0.50.7
Pavlov. Cond. change in total contacts0.40.61.7-0.80.8-0.6-0.0-0.71.3-0.7-0.50.4-0.7-0.41.2
Pavlov. Cond. index score0.50.62.1-0.90.9-0.80.1-0.91.4-0.8-0.60.5-0.8-0.30.8
Pavlov. Cond. latency score0.80.92.9-1.11.1-1.00.2-1.11.7-0.7-0.80.7-0.9-0.60.9
Pavlov. Cond. lever contacts0.20.21.4-0.20.2-0.2-0.5-0.10.7-1.20.1-0.2-0.10.30.6
Pavlov. Cond. magazine entry number1.11.43.51.4-1.51.3-0.71.4-1.90.21.2-1.01.30.6-0.8
Pavlov. Cond. intertrial magazine entries1.52.04.51.6-1.71.4-0.91.6-2.1-0.01.3-1.31.41.2-1.2
Pavlov. Cond. lever-magazine prob. diff.0.40.61.8-0.80.8-0.80.0-0.81.3-0.8-0.60.4-0.7-0.30.7
Pavlov. Cond. response bias0.40.61.8-0.80.8-0.8-0.0-0.71.3-0.9-0.50.4-0.7-0.20.9
Time in closed arm before self-admin0.60.71.00.9-0.90.8-0.91.0-0.6-0.70.8-1.00.71.00.3
Time in closed arm after self-admin0.40.43.2-0.50.4-0.30.2-0.50.9-0.2-0.30.3-0.3-0.01.8
Time in open arm before self-admin0.80.91.7-1.01.3-0.90.6-1.21.3-0.2-0.90.9-0.9-0.9-0.5
Time in open arm after self-admin1.01.12.51.2-1.10.9-0.71.3-1.6-0.10.9-1.01.00.8-0.9
Bone: periosteal estimation0.81.72.61.4-1.31.6-1.31.3-1.2-0.91.4-1.31.41.2-1.4
Bone: periosteal perimeter0.50.82.10.9-0.71.1-0.90.8-0.7-0.81.0-0.80.90.7-1.4
Bone: post-yield work0.20.30.90.5-0.60.6-0.10.5-0.90.20.4-0.40.60.60.5
Progressive ratio test 1 active lever presses0.30.32.7-0.2-0.0-0.10.1-0.10.40.2-0.20.2-0.1-0.21.7
Progressive ratio test 1 breakpoint0.30.32.3-0.30.2-0.20.2-0.30.50.2-0.30.3-0.2-0.41.5
Progressive ratio test 1 inactive lever presses2.32.53.81.7-1.91.6-1.71.7-1.7-1.21.6-1.61.81.40.0
Progressive ratio test 2 active lever presses0.00.00.10.2-0.20.2-0.10.20.00.00.3-0.10.2-0.10.3
Progressive ratio test 2 breakpoint0.00.00.20.1-0.10.20.00.10.00.20.10.00.1-0.10.4
Progressive ratio test 2 inactive lever presses1.01.21.71.0-1.31.0-1.31.2-0.6-1.11.2-1.01.10.81.0
Incentive Sensitization - Responses0.10.10.1-0.10.2-0.20.3-0.20.30.2-0.00.2-0.2-0.4-0.4
Incentive Sensitization - Breakpoint0.00.00.1-0.00.1-0.10.1-0.10.30.00.00.1-0.1-0.2-0.3
Sum of active levers in priming session hrs 5-61.01.01.80.8-0.90.8-1.31.0-1.3-1.11.1-1.00.90.9-0.5
Progressive ratio0.40.51.0-0.71.0-0.80.5-0.70.9-0.1-0.70.5-0.9-0.50.6
Food seeking constrained by brief footshock0.00.10.2-0.30.4-0.20.3-0.30.10.2-0.30.1-0.20.1-0.2
Seeking ratio, punishment vs. effort0.50.61.20.7-1.00.8-0.40.7-1.10.20.6-0.61.00.7-0.8
Retroperitoneal fat weight0.20.72.00.8-0.90.80.30.9-1.41.40.6-0.20.80.00.2
Reaction time number correct0.10.20.7-0.10.50.10.2-0.20.6-0.20.10.3-0.2-0.50.8
Reaction time mean minus median0.60.72.1-0.90.6-0.91.2-0.80.31.5-1.10.8-0.8-0.50.1
Reaction time mean minus median AUC0.71.03.9-0.80.6-0.61.4-0.6-0.02.0-1.01.0-0.7-0.80.8
Reaction time num false alarms0.30.42.10.4-0.60.50.20.3-0.80.90.30.00.6-0.1-1.5
Reaction time num false alarms AUC0.20.31.40.1-0.20.10.5-0.0-0.41.2-0.10.30.2-0.4-1.2
Reaction time trials correct on left0.10.20.7-0.10.50.10.2-0.20.6-0.20.10.3-0.2-0.50.8
Reaction time trials on left0.10.20.7-0.20.60.10.3-0.30.7-0.20.10.4-0.2-0.60.8
Reaction time mean0.71.02.1-0.90.8-1.01.3-0.80.41.5-1.20.9-1.0-0.61.4
Reaction time mean AUC0.60.82.1-0.80.6-0.81.2-0.60.21.5-1.10.8-0.8-0.51.3
Median of all reaction times0.71.03.0-0.90.7-1.01.2-0.70.41.3-1.10.8-0.9-0.61.7
Reaction time omissions1.41.92.6-1.51.5-1.41.5-1.51.61.2-1.31.5-1.3-1.40.6
Reaction time false alarm rate0.30.42.10.1-0.5-0.00.40.1-0.71.2-0.10.10.3-0.0-1.4
Reaction time premature initiation rate0.20.20.60.4-0.40.6-0.30.5-0.80.10.3-0.30.40.20.7
Reaction time premature initiations0.20.31.10.5-0.30.8-0.20.5-0.60.10.5-0.20.50.01.1
Std. dev. reaction times0.40.61.8-0.70.6-0.81.1-0.60.31.3-1.00.7-0.7-0.40.5
Reaction time trials completed0.10.20.7-0.20.60.10.3-0.30.7-0.20.10.4-0.2-0.60.8
Reaction time trials AUC0.20.20.6-0.30.6-0.00.4-0.40.70.0-0.00.5-0.3-0.70.8
Run reversals in cocaine runway, females3.02.94.12.0-1.61.9-1.71.8-1.4-1.61.8-1.91.81.8-1.0
Run reversals in cocaine runway, males0.20.20.6-0.40.5-0.60.3-0.50.70.1-0.30.5-0.5-0.80.0
Latency to leave start box in cocaine runway2.62.83.81.7-1.91.8-1.72.0-1.8-1.01.8-1.81.71.71.0
Latency to leave start box in cocaine runway, F3.94.35.92.2-2.42.3-2.02.4-2.3-1.12.2-2.22.22.10.1
Latency to leave start box in cocaine runway, M0.20.21.3-0.40.4-0.40.1-0.30.6-0.1-0.20.2-0.4-0.21.1
Std. dev. time between licks in bursts1.01.21.9-1.21.1-1.30.9-1.21.00.4-1.31.0-1.4-1.0-0.6
Total sessions with >9 infusions1.51.73.7-1.41.5-1.60.9-1.41.90.2-1.21.2-1.4-1.21.0
Short access day 1 total inactive lever presses1.31.53.81.0-1.21.1-1.71.1-0.4-2.01.3-1.21.11.00.8
Short access day 10 total inactive lever presses1.31.53.01.2-1.21.2-1.51.1-0.9-1.71.3-1.31.21.2-0.1
Short access day 1 total infusions0.10.10.40.2-0.60.2-0.40.3-0.2-0.10.3-0.30.30.30.4
Short access day 10 total infusions0.10.10.4-0.30.1-0.5-0.1-0.10.1-0.3-0.10.1-0.1-0.10.6
Short access total infusions0.30.30.9-0.60.4-0.70.3-0.50.60.2-0.40.5-0.5-0.50.9
Short access day 1 locomotion0.10.10.3-0.20.2-0.30.3-0.20.10.2-0.20.1-0.1-0.1-0.5
Short access day 10 total locomotion0.30.31.1-0.40.4-0.50.8-0.40.20.9-0.40.4-0.3-0.31.0
Short access total locomotion0.40.50.8-0.70.7-0.80.7-0.60.70.6-0.60.7-0.6-0.60.9
One hour access (0.3 mA shock)0.20.20.60.3-0.30.2-0.70.3-0.1-0.80.5-0.40.30.40.2
Compulsive drug intake0.30.31.50.2-0.70.2-0.40.3-0.90.30.2-0.40.20.6-1.2
One hour access (shock baseline)0.10.21.40.10.2-0.0-0.00.10.3-0.30.20.10.2-0.41.2
Social response proportion1.31.42.31.4-1.51.3-1.01.5-1.4-0.21.4-1.21.21.0-0.1
Social responses0.40.51.11.0-0.81.0-0.60.9-0.6-0.21.0-0.60.80.20.1
Social time0.70.91.41.1-1.11.1-0.81.2-1.2-0.31.1-1.01.00.9-0.3
Soleus weight0.20.62.0-0.90.9-0.90.1-1.01.4-0.9-0.50.5-0.8-0.3-0.5
Bone: stiffness0.81.32.81.3-1.31.6-0.61.2-1.70.41.1-0.91.30.9-0.6
Tibialis anterior weight4.013.616.9-4.13.9-3.84.0-4.03.53.4-3.94.0-3.7-3.61.6
Time to tail flick, vehicle, before self-admin0.40.50.60.6-0.80.8-0.70.7-0.7-0.50.6-0.60.60.6-0.8
Time to tail flick, vehicle, after self-admin0.91.03.60.9-0.61.0-1.20.70.2-1.91.1-1.00.90.9-0.1
Time to tail flick, test, before self-admin0.10.11.00.1-0.00.1-0.40.1-0.0-0.30.1-0.20.00.1-1.0
Time to tail flick, test, after self-admin1.81.92.61.6-1.41.5-1.41.6-1.2-0.91.5-1.51.61.4-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.30.5-0.10.5-0.30.30.0-0.50.6-0.40.50.20.2
Delta time to tail flick, test, before/after SA0.90.81.41.0-1.01.1-0.51.1-1.00.00.9-0.81.20.80.1
Tibia length0.10.30.90.6-0.50.9-0.30.5-0.60.10.6-0.40.60.4-0.5
Ambulatory time before self-admin0.50.50.70.9-0.80.8-0.70.7-0.7-0.50.8-0.70.80.7-0.4
Ambulatory time after self-admin3.03.34.61.9-1.81.8-2.11.8-1.4-2.12.0-1.91.71.8-1.5
Bone: tissue strength0.80.81.21.1-0.91.1-0.81.0-1.0-0.30.9-0.91.00.90.6
Total heroin consumption1.72.02.61.5-1.61.5-1.51.3-1.1-1.41.4-1.41.31.4-1.4
Bone: trabecular number0.20.30.5-0.40.4-0.60.7-0.4-0.00.7-0.60.4-0.5-0.4-0.6
Bone: trabecular spacing0.30.31.7-0.20.10.10.6-0.1-0.21.3-0.30.5-0.2-0.51.1
Bone: trabecular thickness0.20.20.80.4-0.30.2-0.50.4-0.0-0.90.4-0.50.30.50.6
Bone: trabecular tissue density0.40.51.8-0.70.5-0.61.0-0.70.21.4-0.80.8-0.6-0.60.0
Water consumed over 24 hours1.62.02.71.5-1.51.5-1.61.5-1.2-1.31.6-1.41.51.1-0.5
Number of responses in last shaping day0.40.40.7-0.70.5-0.80.5-0.60.50.6-0.70.7-0.7-0.70.3