Hub : Genes

Ube3d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ube3d 0.6 0.13 1.1e-13 -0 0.12 0.12 0.12 4.3e-01 1.0e-13 1.8e-13 1.0e-12
2 Brain gene expression Ube3d 0.07 0.06 2.8e-06 0.07 0.05 0.06 0.07 7.6e-07 4.2e-05 2.6e-06 3.4e-07
3 IC gene expression Ube3d 0.07 0.05 3.6e-03 0.04 0.05 0.02 0.04 1.2e-02 5.3e-03 5.0e-02 1.1e-02
4 BLA gene expression Ube3d 0.2 0.13 1.1e-07 0.15 0.14 0.14 0.15 2.6e-08 8.4e-08 6.5e-08 2.6e-08
5 Eye alternative polyA XM_039081532.2 0.23 0.16 7.3e-03 0.13 0.08 0.07 0.09 4.7e-03 2.3e-02 2.9e-02 1.6e-02
6 LHb mRNA stability Ube3d 0.14 0.09 4.0e-03 0.12 0.04 0.1 0.01 1.2e-03 3.6e-02 2.6e-03 2.2e-01
7 pVTA gene expression Ube3d 0.04 0.03 5.5e-03 0.03 0.02 0.01 0.02 2.7e-03 1.7e-02 2.5e-02 7.0e-03
8 PL gene expression Ube3d 0.2 0.1 0.0e+00 0.18 0.22 0.22 0.23 1.2e-19 1.7e-23 3.7e-24 2.4e-24
9 NAcc gene expression Ube3d 0.14 0.08 6.2e-09 0.04 0.06 0.06 0.06 3.4e-07 9.9e-10 4.9e-10 5.9e-09
10 Liver gene expression Ube3d 0.58 0.11 0.0e+00 0.05 0.16 0.15 0.14 1.3e-06 1.7e-17 8.6e-17 1.4e-15
11 OFC gene expression Ube3d 0.34 0.23 2.9e-04 0.09 0.06 0.11 0.08 3.2e-03 1.3e-02 1.3e-03 5.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density2.23.85.31.21.72.12.1-2.12.12.12.32.0-2.01.4
Area under the delay curve5.66.510.72.0-2.9-2.8-3.02.8-2.9-2.8-2.0-3.30.8-1.8
BMI with tail0.10.41.3-1.1-0.4-0.6-0.40.5-0.6-0.5-0.6-0.70.7-0.1
BMI without tail0.00.00.2-0.0-0.00.0-0.0-0.0-0.10.10.10.2-0.40.0
Body weight0.10.53.4-1.90.50.20.3-0.30.20.4-0.3-0.20.90.6
Weight adjusted by age0.20.30.80.30.50.70.3-0.50.40.50.90.4-0.70.8
Bone surface4.27.710.80.82.63.13.1-3.03.03.03.33.0-2.62.1
Bone volume3.56.210.31.82.02.72.6-2.52.52.53.22.6-3.01.7
Breakpoint value in progressive ratio session1.51.83.2-0.81.51.31.7-1.71.81.50.91.1-0.11.3
Number of licking bursts0.20.30.6-0.60.60.60.6-0.70.60.70.20.80.00.2
Context. condit. distance diff. score1.51.82.5-0.61.61.61.3-1.31.31.31.51.5-1.11.3
Locomotion velocity, session 12.62.85.40.8-2.3-2.0-1.91.8-1.8-1.8-1.6-1.50.4-1.6
Locomotion distance, session 11.01.32.21.0-1.5-1.2-1.51.3-1.3-1.2-0.6-0.9-0.5-0.8
Locomotion velocity, session 23.03.54.80.4-2.2-2.1-2.22.1-2.1-2.1-1.9-2.01.1-1.5
Locomotion distance, session 21.21.73.01.0-1.6-1.3-1.71.6-1.6-1.6-0.4-1.1-0.7-0.8
Locomotion velocity, session 30.60.74.21.2-0.60.2-0.10.2-0.2-0.21.10.4-2.00.1
Locomotion distance, session 32.32.54.20.91.51.81.6-1.61.61.62.11.6-1.71.3
Stereotopy head waving bouts, day 30.20.20.7-0.3-0.4-0.4-0.20.1-0.1-0.2-0.9-0.50.7-0.3
Stereotopy head waving duration, day 32.63.14.5-0.1-2.1-2.0-2.12.0-2.0-2.1-1.8-1.90.6-1.3
Locomotion velocity, session 71.41.53.30.21.31.40.9-0.91.00.91.81.4-1.81.2
Locomotion distance, session 71.11.42.0-0.71.41.41.2-1.31.31.31.21.4-0.60.9
Stereotopy head waving bouts, day 71.01.22.40.5-1.5-1.2-1.31.2-1.2-1.3-0.7-0.9-0.2-1.1
Stereotopy head waving duration, day 70.60.71.10.4-1.1-0.8-1.01.0-1.0-1.0-0.3-0.5-0.7-0.7
Locomotion velocity, session 80.30.30.60.2-0.5-0.4-0.80.7-0.7-0.7-0.00.0-0.8-0.6
Locomotion distance, session 81.11.74.1-0.01.21.40.9-0.91.00.91.91.6-2.01.1
Degree of sensitization distance0.80.91.6-1.3-0.6-0.9-0.80.8-0.8-0.8-1.2-0.71.2-0.8
Degree of sensitization stereotypy1.01.01.90.8-1.4-1.0-1.31.2-1.2-1.2-0.4-0.8-0.5-0.9
Conditioned locomotion2.42.74.91.2-1.9-1.9-1.21.2-1.2-1.2-2.2-2.12.2-1.4
Cocaine response after cond. corrected1.72.13.50.7-1.9-1.8-1.51.6-1.6-1.6-1.3-1.30.2-1.6
Cocaine response after cond. not corrected1.41.62.70.7-1.7-1.5-1.31.4-1.4-1.4-1.1-1.10.1-1.4
Cocaine response before conditioning0.70.81.6-0.21.21.11.1-1.01.01.00.80.9-0.20.9
Saline control response0.91.22.5-0.2-1.0-1.2-1.11.1-1.1-1.1-1.1-1.61.5-0.3
Bone: connectivity density2.33.55.00.51.82.12.2-2.12.12.12.02.2-1.51.3
Bone: cortical apparent density9.012.418.91.4-4.4-4.0-4.03.9-4.0-3.9-3.2-4.01.6-2.7
Bone: cortical area0.20.31.81.4-0.5-0.3-0.10.3-0.2-0.30.1-0.2-0.6-0.2
Bone: cortical porosity0.40.50.70.30.80.80.8-0.70.80.70.70.7-0.50.4
Bone: cortical porosity0.20.20.30.50.40.40.5-0.50.50.50.40.3-0.30.1
Bone: cortical thickness0.71.21.91.4-1.4-1.2-1.01.2-1.2-1.2-0.7-0.9-0.2-1.1
Bone: cortical thickness3.33.96.40.2-2.2-2.3-2.52.5-2.5-2.5-1.4-1.9-0.0-1.6
Bone: cortical tissue density8.912.118.51.3-4.3-4.0-4.03.9-4.0-3.9-3.2-3.91.6-2.7
Condit. Reinf. active minus inactive responses0.20.20.50.20.30.30.6-0.60.70.50.10.10.60.4
Condit. Reinf. active-inactive response ratio0.40.42.1-0.3-0.5-0.7-0.20.3-0.2-0.4-0.8-0.91.5-0.2
Condit. Reinf. active responses0.10.10.20.40.20.10.4-0.40.50.3-0.00.00.30.3
Condit. Reinf. inactive responses0.10.10.60.6-0.00.20.0-0.20.10.10.30.4-0.70.0
Incentive salience index mean0.30.31.9-0.90.0-0.4-0.10.1-0.0-0.1-0.8-0.51.4-0.1
Condit. Reinf. lever presses1.01.43.9-2.0-0.2-1.0-0.70.8-0.7-0.8-1.6-0.91.9-0.7
Condit. Reinf. active minus inactive responses1.21.62.81.00.81.31.2-1.21.21.21.61.3-1.70.9
Condit. Reinf. active-inactive response ratio2.02.33.30.61.21.61.8-1.81.81.81.51.8-1.41.0
Condit. Reinf. active responses1.31.84.72.00.41.21.0-1.01.01.01.91.1-2.20.9
Condit. Reinf. inactive responses0.81.06.52.5-0.30.40.2-0.10.20.11.20.1-1.60.4
Condit. Reinf. lever presses0.00.10.40.3-0.4-0.1-0.10.1-0.1-0.10.2-0.1-0.60.0
Condit. Reinf. lever reinforcers received1.21.65.12.00.21.00.9-0.80.80.81.81.0-2.30.8
Conditioned reinforcement - actives2.23.87.12.11.41.91.8-1.91.91.92.51.7-2.71.3
Conditioned reinforcement - inactives0.30.41.50.60.30.50.5-0.50.40.50.80.7-1.2-0.1
Conditioned locomotion2.02.64.32.10.91.51.7-1.71.61.71.81.6-2.00.7
Patch foraging indifference point 0 sec1.12.13.61.01.71.51.9-1.81.81.71.01.4-0.51.0
Patch foraging indifference point AUC0.71.06.2-2.51.40.70.5-0.40.50.40.10.70.30.5
Delay disc. indifference point, 0s delay1.82.03.82.0-1.7-1.4-1.51.4-1.5-1.4-0.8-1.80.0-0.8
Delay disc. indifference point, 16s delay4.14.56.40.7-2.3-2.3-2.42.4-2.3-2.4-2.0-2.51.3-1.8
Delay disc. indifference point, 2s delay1.41.56.72.6-1.4-0.8-1.11.0-1.1-1.00.2-1.4-1.1-0.3
Delay disc. indifference point, 24s delay3.23.65.81.0-2.1-2.2-2.02.1-2.0-2.1-1.9-2.41.3-1.3
Delay disc. indifference point, 4s delay0.20.21.10.2-0.3-0.4-0.70.5-0.6-0.5-0.2-1.10.10.3
Delay disc. indifference point, 8s delay4.85.78.52.6-2.9-2.5-2.72.6-2.6-2.6-1.6-2.90.1-1.6
Indifference point function ln k0.50.97.72.8-1.0-0.3-0.10.0-0.1-0.00.5-0.4-0.7-0.3
Indifference point function log k0.50.97.72.8-1.0-0.3-0.10.0-0.1-0.00.5-0.4-0.7-0.3
Patch foraging total patch changes 0 sec1.52.74.51.31.81.72.1-2.02.02.01.31.6-0.81.2
Patch foraging total patch changes 12 sec0.40.51.1-0.10.90.71.1-0.90.90.8-0.00.8-0.10.5
Patch foraging total patch changes 18 sec1.31.94.3-1.52.11.51.4-1.41.41.30.81.7-0.40.9
Patch foraging total patch changes 24 sec1.52.65.7-1.82.41.71.7-1.61.61.51.11.6-0.41.5
Patch foraging total patch changes 6 sec4.67.012.3-0.83.53.13.1-3.03.02.92.22.9-1.12.2
Patch foraging time to switch 0 sec1.32.63.5-1.4-1.6-1.7-1.81.9-1.8-1.8-1.6-1.30.9-1.4
Patch foraging water rate 0 sec1.22.54.10.61.91.81.9-2.02.01.91.11.4-0.21.4
Patch foraging water rate 12 sec1.02.14.12.00.61.31.7-1.61.81.61.31.6-1.10.5
Patch foraging water rate 18 sec0.20.31.10.20.40.60.2-0.30.30.31.00.3-0.80.9
Patch foraging water rate 24 sec1.11.52.31.51.01.31.2-1.31.31.31.41.1-1.00.8
Patch foraging water rate 6 sec0.81.25.82.40.00.70.6-0.70.70.81.20.6-1.60.5
Seeking ratio, delayed vs. immediate footshock0.20.20.70.00.20.60.5-0.30.50.30.40.8-0.60.1
Distance traveled before self-admin0.30.41.40.40.20.60.5-0.40.40.30.80.6-1.20.7
Distance traveled after self-admin0.20.30.90.5-0.9-0.6-0.60.5-0.5-0.5-0.3-0.7-0.20.1
Extensor digitorum longus weight0.10.41.7-1.30.2-0.4-0.30.2-0.2-0.2-0.8-0.51.10.1
Bone: elastic displacement0.40.52.7-1.00.1-0.30.2-0.30.30.3-1.1-0.41.6-0.1
Bone: elastic work0.60.82.6-0.9-0.4-0.9-0.50.4-0.4-0.4-1.5-0.91.6-0.8
Bone: endosteal estimation1.53.34.5-0.81.92.12.0-2.02.12.02.01.7-1.01.8
Bone: endosteal perimeter0.71.42.01.10.81.31.4-1.41.41.41.31.0-0.91.1
Epididymis fat weight1.24.16.8-1.02.52.02.6-2.52.62.61.21.70.11.8
Delta time in closed arm before/after self-admin1.11.02.3-0.5-0.9-1.1-0.91.0-0.9-0.9-1.4-1.21.5-0.5
Delta time in open arm before/after self-admin3.43.329.3-5.41.40.40.4-0.60.50.5-0.80.91.70.3
Diff in mean of infusions in LGA sessions1.11.32.61.60.70.91.4-1.31.41.31.00.5-1.01.1
Delay discount exponential model param5.66.29.9-1.72.82.72.9-2.82.82.81.93.2-0.81.8
Extinction: sum of active levers before priming0.10.10.50.5-0.4-0.40.20.00.1-0.1-0.7-0.40.5-0.2
Active lever presses in extinction session 61.31.32.00.41.11.21.4-1.31.41.11.01.3-0.71.1
Bone: final force0.00.00.0-0.0-0.2-0.10.00.0-0.0-0.00.1-0.0-0.2-0.2
Bone: final moment0.00.00.0-0.2-0.00.00.2-0.10.10.10.10.0-0.1-0.1
Food consumed during 24 hour testing period0.20.21.81.40.10.10.10.00.00.00.5-0.2-0.60.2
Glucose0.50.82.11.00.51.00.7-0.60.60.71.40.7-1.40.9
Heart weight1.42.27.30.51.21.50.9-1.01.01.02.31.4-2.71.1
Delay discount hyperbolic model param4.14.67.7-1.72.42.32.5-2.42.42.41.62.8-0.51.5
Intermittent access intake day 1-15 change0.81.63.80.31.51.51.0-1.01.01.02.01.2-1.61.1
Intermittent access intake escalation1.02.14.2-0.61.91.81.2-1.21.21.22.11.4-1.41.4
Intermittent access intake escalation 22.42.74.8-1.12.22.01.6-1.51.51.52.11.4-1.11.6
Intermitt. access day 1 inactive lever presses0.41.43.11.8-1.7-1.1-1.21.1-1.2-1.1-0.5-0.6-0.6-1.3
Intermitt. access day 15 inactive lever presses0.51.05.02.2-0.9-0.4-0.60.6-0.6-0.60.7-0.3-1.8-0.4
Intermitt. access escalation Index0.40.61.10.40.80.90.7-0.80.60.81.10.8-0.90.6
Intermittent access day 1 total infusions0.30.44.02.0-0.6-0.20.0-0.1-0.10.1-0.20.1-0.4-0.5
Intermittent access day 15 total infusions0.91.32.50.11.21.40.9-1.00.81.01.61.3-1.31.1
Intermittent access terminal intake (last 3 days)1.82.43.5-0.11.61.91.5-1.61.41.61.91.8-1.41.4
Intermittent access total infusions0.60.71.41.20.40.80.7-0.80.60.80.81.2-1.20.1
Intermittent access day 1 locomotion1.01.39.53.1-1.4-0.6-0.50.4-0.5-0.4-0.2-0.3-0.7-0.9
Intermittent access day 15 total locomotion0.81.511.93.4-1.2-0.2-0.10.1-0.2-0.10.40.1-1.4-0.9
Intermittent access total locomotion1.21.411.63.4-0.70.20.4-0.50.40.50.60.4-1.4-0.4
Intermittent access standard deviation0.61.25.52.30.20.90.7-0.80.70.81.01.3-1.3-0.4
Left kidney weight0.52.27.6-2.8-0.6-1.3-0.70.9-0.9-0.8-2.1-1.52.3-0.4
Right kidney weight0.10.53.9-2.00.60.10.4-0.20.20.3-0.50.00.80.2
Cocaine induced anxiety0.10.20.3-0.3-0.4-0.4-0.50.5-0.5-0.5-0.0-0.5-0.2-0.1
Post-drug Anxiety0.10.10.30.3-0.4-0.3-0.40.4-0.4-0.40.3-0.5-0.50.1
Baseline Anxiety0.10.20.70.90.10.30.4-0.30.40.30.40.2-0.40.2
Tail length0.10.41.0-1.00.80.60.3-0.50.50.60.30.6-0.30.7
Length with tail0.10.40.7-0.50.80.70.7-0.70.70.80.40.3-0.10.8
Length without tail0.10.41.1-0.30.60.70.8-0.70.70.70.80.1-0.41.1
Times rat made contact with spout1.61.86.32.5-1.8-1.1-1.21.2-1.2-1.2-0.0-1.1-1.3-0.7
Lifetime Intake0.91.12.71.60.41.00.9-1.10.81.11.01.3-1.30.2
Liver weight, left0.20.32.10.50.10.30.10.00.0-0.00.70.2-1.40.3
Liver weight, right1.01.83.20.2-1.8-1.4-1.71.7-1.8-1.7-0.9-1.30.1-0.7
Locomotor activity2.03.24.71.41.51.91.9-2.12.02.22.01.5-1.61.2
Locomotor testing distance1.42.54.72.21.21.61.3-1.81.61.81.81.0-1.71.0
Locomotor testing rearing0.61.38.72.9-0.20.50.2-0.50.50.61.2-0.3-1.40.5
Locomotion in novel chamber0.60.83.0-1.7-0.6-0.7-0.60.8-0.7-0.8-1.2-0.10.9-0.6
Locomotion in novel chamber post-restriction0.20.40.8-0.2-0.8-0.9-0.50.7-0.5-0.7-0.7-0.70.1-0.5
Fecal boli incidents, locomotor time 10.20.20.50.1-0.2-0.3-0.60.6-0.6-0.70.4-0.5-0.7-0.1
Change in fecal boli incidents, locomotor task0.00.00.2-0.5-0.00.20.0-0.00.00.20.20.3-0.1-0.1
Time >=10cm from walls, locomotor time 10.30.30.70.1-0.4-0.5-0.80.8-0.8-0.8-0.2-0.30.1-0.7
Bouts of movement, locomotor time 11.51.72.90.4-1.6-1.6-1.21.2-1.1-1.2-1.7-1.11.4-1.4
Total resting periods, locomotor time 11.51.62.9-0.0-1.5-1.5-1.11.1-1.0-1.2-1.7-1.11.5-1.4
Rest time, locomotor task time 19.912.319.01.9-4.4-4.1-3.83.9-3.7-3.8-3.3-4.01.8-3.0
Distance moved, locomotor task time 18.512.720.9-2.74.64.03.8-3.83.83.73.04.3-1.32.8
Vertical activity count, locomotor time 13.17.518.6-4.33.82.92.4-2.42.42.31.93.0-0.22.4
Time >=10cm from walls, locomotor time 20.20.30.90.4-0.6-0.6-0.60.5-0.6-0.5-0.7-0.00.3-1.0
Bouts of movement, locomotor time 20.30.54.22.1-0.7-0.30.20.00.30.00.2-0.4-0.7-0.2
Total resting periods, locomotor time 20.61.06.72.6-1.2-0.7-0.40.6-0.4-0.5-0.1-0.9-0.7-0.5
Rest time, locomotor task time 29.512.015.91.2-3.8-3.9-4.03.9-3.9-4.0-3.2-4.02.1-2.9
Distance moved, locomotor task time 28.510.117.4-2.43.73.53.6-3.53.53.52.64.2-1.42.1
Vertical activity count, locomotor time 24.56.210.5-2.63.22.72.5-2.42.42.42.23.0-1.41.9
Light reinforcement 10.20.40.9-1.00.80.50.7-0.80.70.7-0.00.40.70.6
Light reinforcement 21.92.98.5-2.1-1.1-1.5-1.21.2-1.3-1.2-2.4-1.32.9-1.4
Bone: marrow area1.43.04.1-0.91.82.01.9-1.92.01.91.91.7-0.91.7
Bone: maximum diameter0.30.51.71.3-0.00.50.5-0.30.40.31.00.5-1.30.4
Bone: maximum force0.10.21.2-1.10.20.00.2-0.10.10.1-0.30.10.5-0.2
Bone: maximum moment0.10.21.3-1.10.3-0.00.2-0.20.20.2-0.30.10.7-0.2
Mean time between licks in bursts0.30.73.3-1.0-0.6-0.6-0.10.1-0.1-0.1-1.4-0.21.8-0.8
Mean num. licks in bursts1.21.94.42.1-1.7-1.3-1.41.5-1.5-1.5-0.1-1.5-0.9-0.6
Cd content in liver0.10.11.11.0-0.1-0.10.3-0.20.20.20.0-0.20.0-0.0
Co content in liver1.31.63.30.9-1.3-1.4-0.80.8-0.8-0.8-1.6-1.81.8-0.8
Cu content in liver0.30.30.90.60.10.50.5-0.50.50.50.90.5-0.90.2
Fe content in liver1.62.02.91.51.01.41.4-1.41.41.41.71.5-1.60.8
K content in liver1.51.43.61.9-1.6-1.0-1.21.3-1.2-1.3-0.3-1.1-0.3-1.1
Mg content in liver2.62.64.61.4-2.1-1.6-1.91.9-1.9-1.9-0.8-1.80.0-1.4
Mn content in liver0.10.10.60.7-0.1-0.0-0.10.2-0.1-0.20.1-0.40.20.1
Na content in liver0.30.30.5-0.60.70.60.7-0.60.60.60.20.60.30.3
Rb content in liver0.81.04.70.50.70.90.3-0.30.30.31.70.7-2.20.7
Se content in liver1.31.52.41.50.91.21.3-1.31.31.31.31.2-1.10.5
Sr content in liver1.61.45.8-2.41.60.80.9-0.90.90.90.00.61.21.0
Zn content in liver0.50.63.71.9-0.8-0.2-0.30.3-0.3-0.30.6-0.4-1.0-0.2
Bone: minimum diameter1.42.53.31.71.21.71.7-1.71.71.71.81.3-1.41.3
Time in familiar zone, hab. session 11.61.62.50.51.21.41.5-1.61.61.51.11.3-0.51.0
Time in novel zone, hab. session 10.90.91.60.3-1.3-1.0-1.11.2-1.2-1.2-0.6-1.10.3-0.6
Total zone transitions, hab. session 10.30.40.70.7-0.8-0.6-0.80.7-0.7-0.7-0.5-0.2-0.4-0.8
Total locomotion distance, hab. session 10.50.71.61.3-1.0-0.6-1.00.8-0.8-0.8-0.1-0.3-1.1-0.6
Locomotion velocity, hab. session 11.11.62.91.0-1.5-1.3-1.71.5-1.5-1.5-0.8-1.0-0.7-1.1
Time in familiar zone, hab. session 21.01.05.41.7-0.10.60.0-0.10.10.21.40.6-2.30.3
Time in novel zone, hab. session 20.70.72.7-0.7-0.5-0.9-0.50.6-0.6-0.6-1.1-1.01.6-0.5
Total zone transitions, hab. session 20.30.40.9-0.9-0.3-0.5-0.90.7-0.7-0.7-0.50.0-0.0-0.5
Total locomotion distance, hab. session 20.30.31.10.3-0.5-0.3-0.80.7-0.7-0.70.20.1-1.1-0.2
Locomotion velocity, hab. session 20.20.30.70.0-0.5-0.4-0.80.8-0.8-0.8-0.1-0.1-0.7-0.3
Novel to familiar place preference ratio2.93.25.2-1.22.32.02.1-2.02.02.01.41.90.11.4
Novelty place preference2.02.23.5-0.91.91.71.7-1.61.61.61.31.6-0.01.3
Time in novel zone, NPP test1.51.62.6-0.71.61.51.5-1.41.41.41.21.4-0.11.1
Total zone transitions, NPP test1.82.64.51.1-1.9-1.7-2.12.0-2.0-2.0-0.9-1.2-0.7-1.3
Total locomotion distance, NPP test0.70.91.61.2-1.3-0.9-1.11.1-1.1-1.1-0.2-0.4-1.0-0.7
Locomotion velocity, NPP test0.40.61.31.1-1.0-0.6-0.80.8-0.8-0.80.1-0.2-1.1-0.5
Intraocular pressure1.21.711.33.4-1.7-1.0-0.30.2-0.2-0.3-0.9-0.80.4-1.4
Delta distance traveled before/after self-admin0.40.51.40.6-0.8-0.7-0.70.5-0.5-0.4-0.7-1.20.8-0.2
Delta ambulatory time before/after self-admin0.40.51.41.2-0.9-0.7-0.70.5-0.6-0.3-0.5-1.20.5-0.2
Parametrial fat weight0.71.53.00.31.21.21.6-1.71.71.70.70.50.11.2
Pavlov. Cond. lever latency0.60.73.11.5-0.40.50.1-0.00.0-0.01.20.4-1.80.5
Pavlov. Cond. magazine entry latency0.50.74.3-0.90.2-0.4-0.20.0-0.00.0-1.1-0.82.1-0.2
Pavlov. Cond. change in total contacts1.31.43.6-1.91.60.91.2-1.21.21.20.00.61.30.8
Pavlov. Cond. index score0.70.84.3-1.50.4-0.4-0.20.1-0.1-0.0-1.2-0.72.1-0.3
Pavlov. Cond. latency score0.50.63.3-1.10.3-0.5-0.20.1-0.1-0.0-1.2-0.61.8-0.4
Pavlov. Cond. lever contacts0.91.14.8-1.90.5-0.6-0.20.1-0.2-0.1-1.4-0.62.2-0.5
Pavlov. Cond. magazine entry number1.11.35.51.10.41.00.8-0.70.70.61.71.4-2.40.5
Pavlov. Cond. intertrial magazine entries3.44.17.71.11.72.21.8-1.81.91.82.82.2-2.81.5
Pavlov. Cond. lever-magazine prob. diff.0.81.05.0-1.90.6-0.4-0.1-0.00.00.1-1.2-0.62.2-0.1
Pavlov. Cond. response bias1.21.56.6-1.8-0.0-0.9-0.60.5-0.5-0.4-1.8-1.12.6-0.5
Pavlov. Cond. lever latency0.10.10.20.00.50.40.5-0.40.40.40.30.5-0.00.2
Pavlov. Cond. magazine entry latency0.20.21.31.2-0.5-0.20.1-0.00.00.00.0-0.1-0.4-0.4
Pavlov. Cond. change in total contacts0.30.41.81.1-0.7-0.2-0.50.4-0.4-0.40.4-0.2-1.3-0.0
Pavlov. Cond. index score0.20.30.70.6-0.8-0.6-0.60.5-0.5-0.5-0.2-0.5-0.4-0.4
Pavlov. Cond. latency score0.30.40.80.6-0.9-0.7-0.70.6-0.6-0.6-0.3-0.7-0.2-0.5
Pavlov. Cond. lever contacts0.40.50.90.3-1.0-0.8-0.90.8-0.8-0.8-0.6-0.90.2-0.4
Pavlov. Cond. magazine entry number0.20.20.9-0.90.50.20.2-0.20.20.2-0.20.10.90.3
Pavlov. Cond. intertrial magazine entries1.21.83.9-1.22.01.51.4-1.41.41.40.51.40.51.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.7-0.7-0.5-0.40.4-0.4-0.4-0.2-0.4-0.3-0.5
Pavlov. Cond. response bias0.10.20.80.9-0.7-0.3-0.30.3-0.3-0.30.0-0.3-0.6-0.2
Time in closed arm before self-admin0.30.31.51.20.20.40.3-0.40.30.50.7-0.1-1.00.3
Time in closed arm after self-admin0.40.42.21.50.30.50.5-0.60.50.70.60.3-0.80.2
Time in open arm before self-admin1.01.02.91.70.51.00.8-0.60.70.51.40.8-1.41.0
Time in open arm after self-admin1.21.310.9-3.30.80.30.5-0.40.40.3-0.60.51.30.4
Bone: periosteal estimation0.81.62.60.11.11.41.4-1.41.41.41.61.2-1.21.2
Bone: periosteal perimeter0.50.94.42.10.20.60.9-0.80.80.80.90.4-0.90.5
Bone: post-yield work1.01.42.7-1.61.61.21.2-1.21.21.20.81.4-0.40.7
Progressive ratio test 1 active lever presses0.91.14.92.20.20.80.8-1.10.81.10.71.2-1.10.1
Progressive ratio test 1 breakpoint0.81.05.22.3-0.00.60.7-1.00.71.00.51.0-1.00.0
Progressive ratio test 1 inactive lever presses0.91.311.43.4-0.9-0.20.2-0.30.20.30.10.1-1.0-0.6
Progressive ratio test 2 active lever presses3.44.06.70.92.02.31.9-2.01.82.02.61.9-2.12.0
Progressive ratio test 2 breakpoint3.64.16.70.92.02.42.0-2.01.92.02.61.9-2.12.0
Progressive ratio test 2 inactive lever presses1.22.09.63.10.10.90.8-0.80.70.81.70.8-2.20.6
Incentive Sensitization - Responses3.95.59.6-0.62.92.72.3-2.12.22.13.12.0-2.32.6
Incentive Sensitization - Breakpoint4.45.710.1-0.62.92.82.3-2.12.22.13.22.1-2.32.6
Sum of active levers in priming session hrs 5-60.20.21.61.3-0.4-0.10.2-0.00.1-0.10.10.1-0.2-0.1
Progressive ratio0.40.71.21.10.91.00.7-0.60.70.61.10.5-0.90.7
Food seeking constrained by brief footshock0.60.72.40.70.50.80.6-0.50.50.51.31.2-1.50.1
Seeking ratio, punishment vs. effort0.30.42.8-1.7-0.2-0.5-0.40.3-0.4-0.3-0.50.30.4-0.6
Retroperitoneal fat weight0.20.93.01.7-0.00.70.9-0.80.90.91.00.7-1.40.1
Reaction time number correct0.81.52.70.71.01.31.2-1.21.21.21.61.0-1.31.2
Reaction time mean minus median0.41.02.0-0.4-1.1-1.0-1.31.4-1.4-1.4-0.5-1.00.0-0.5
Reaction time mean minus median AUC0.41.01.80.4-1.3-1.0-1.31.3-1.3-1.3-0.1-0.9-0.5-0.4
Reaction time num false alarms3.34.76.41.02.22.32.5-2.52.52.52.42.0-2.11.3
Reaction time num false alarms AUC3.04.77.10.52.42.32.6-2.62.62.72.11.9-1.71.3
Reaction time trials correct on left0.81.52.70.71.01.31.2-1.21.21.21.61.0-1.31.2
Reaction time trials on left0.81.52.70.71.01.41.2-1.31.31.31.71.0-1.31.2
Reaction time mean1.21.83.40.1-1.8-1.5-1.71.7-1.7-1.7-0.8-1.0-0.1-1.2
Reaction time mean AUC0.71.22.3-0.2-1.5-1.2-1.31.4-1.4-1.4-0.6-0.7-0.0-0.9
Median of all reaction times1.21.73.30.0-1.8-1.4-1.61.6-1.6-1.6-0.8-0.8-0.1-1.2
Reaction time omissions0.00.10.30.1-0.10.00.2-0.10.10.00.10.5-0.6-0.4
Reaction time false alarm rate1.41.93.20.11.61.41.8-1.81.81.81.11.3-0.90.6
Reaction time premature initiation rate0.71.02.11.50.60.91.4-1.21.21.20.70.7-0.40.6
Reaction time premature initiations1.01.74.42.10.71.21.6-1.51.51.41.20.9-0.90.9
Std. dev. reaction times0.61.01.90.3-1.4-1.1-1.21.3-1.3-1.3-0.4-0.7-0.2-0.9
Reaction time trials completed0.81.52.70.71.01.41.2-1.31.31.31.71.0-1.31.2
Reaction time trials AUC1.01.93.30.71.21.51.3-1.41.41.41.81.2-1.51.4
Run reversals in cocaine runway, females0.60.62.9-1.7-0.1-0.6-0.40.4-0.4-0.4-1.0-0.41.3-0.4
Run reversals in cocaine runway, males0.60.61.6-0.21.01.00.7-0.70.60.71.10.4-0.31.2
Latency to leave start box in cocaine runway3.03.410.1-3.2-0.6-1.2-2.12.1-2.0-2.1-1.3-1.51.8-0.7
Latency to leave start box in cocaine runway, F1.11.26.6-2.60.5-0.2-1.11.0-1.0-1.0-0.4-0.61.3-0.1
Latency to leave start box in cocaine runway, M3.33.16.8-2.6-1.3-1.5-1.91.9-1.9-1.9-1.8-1.31.5-1.1
Std. dev. time between licks in bursts1.01.48.4-1.80.0-0.50.4-0.30.30.2-1.8-0.42.9-0.3
Total sessions with >9 infusions1.62.010.33.20.21.01.1-1.61.21.60.71.2-1.00.2
Short access day 1 total inactive lever presses1.01.33.11.7-1.6-1.0-1.21.0-1.2-1.0-0.8-0.60.0-1.3
Short access day 10 total inactive lever presses0.61.42.00.1-1.3-1.3-1.21.3-1.2-1.3-1.4-1.00.9-1.3
Short access day 1 total infusions1.52.017.34.2-1.4-0.40.1-0.40.00.4-0.8-0.10.2-1.1
Short access day 10 total infusions0.10.10.30.5-0.2-0.10.2-0.30.10.3-0.40.20.2-0.3
Short access total infusions1.21.57.12.70.10.90.9-1.20.91.20.91.2-1.30.1
Short access day 1 locomotion1.82.313.03.6-2.0-1.1-1.30.9-1.2-0.9-0.4-1.2-0.8-0.7
Short access day 10 total locomotion0.81.512.33.5-1.5-0.5-0.10.0-0.1-0.0-0.3-0.1-0.9-0.9
Short access total locomotion1.41.714.73.8-0.90.10.2-0.50.30.50.40.6-1.5-0.6
One hour access (0.3 mA shock)3.54.09.22.51.01.91.6-1.71.61.72.71.9-3.01.2
Compulsive drug intake0.80.92.71.60.40.90.7-0.90.80.91.40.4-1.00.6
One hour access (shock baseline)0.40.61.70.10.70.80.7-0.60.60.61.01.1-1.30.6
Social response proportion0.50.63.1-1.20.4-0.20.1-0.20.20.3-1.2-0.21.8-0.1
Social responses0.50.62.01.0-0.6-0.80.1-0.00.00.1-1.4-0.91.4-0.4
Social time0.30.41.91.4-0.6-0.7-0.10.2-0.1-0.1-0.8-0.70.7-0.1
Soleus weight1.75.110.7-1.63.32.42.5-2.62.62.61.41.90.32.2
Bone: stiffness0.10.21.1-0.1-0.20.1-0.30.4-0.3-0.40.50.4-1.1-0.2
Tibialis anterior weight0.10.20.7-0.80.70.30.2-0.30.40.30.10.10.40.7
Time to tail flick, vehicle, before self-admin0.50.53.61.90.20.40.5-0.50.50.40.50.2-0.60.2
Time to tail flick, vehicle, after self-admin0.30.40.70.6-0.7-0.7-0.70.8-0.7-0.9-0.3-0.7-0.5-0.3
Time to tail flick, test, before self-admin0.00.00.1-0.30.10.0-0.1-0.0-0.0-0.10.10.2-0.20.0
Time to tail flick, test, after self-admin0.10.10.4-0.1-0.2-0.1-0.20.2-0.2-0.30.30.1-0.6-0.3
Delta time to tail flick, vehicle, before/after SA1.00.91.40.3-1.2-1.2-1.11.2-1.1-1.2-0.7-0.8-0.2-1.0
Delta time to tail flick, test, before/after SA0.30.30.4-0.3-0.7-0.6-0.60.6-0.6-0.6-0.5-0.60.2-0.6
Tibia length1.02.64.7-2.2-1.5-1.6-1.41.7-1.7-1.7-1.8-1.31.8-1.0
Ambulatory time before self-admin0.20.32.3-1.5-0.0-0.1-0.20.3-0.3-0.4-0.30.10.10.1
Ambulatory time after self-admin0.80.91.4-0.6-1.1-1.1-1.11.0-1.0-0.9-1.0-1.20.8-0.4
Bone: tissue strength0.10.10.6-0.60.00.10.2-0.20.20.2-0.30.00.8-0.1
Total heroin consumption0.50.61.4-1.10.90.80.7-0.70.70.50.60.6-0.51.2
Bone: trabecular number2.13.54.71.01.72.12.0-2.02.02.02.22.0-1.71.5
Bone: trabecular spacing3.44.56.70.3-2.5-2.4-2.62.6-2.6-2.6-1.7-2.00.6-1.8
Bone: trabecular thickness1.31.62.41.01.11.31.3-1.31.31.31.51.3-1.50.9
Bone: trabecular tissue density3.04.47.1-1.0-1.8-2.3-2.12.1-2.1-2.1-2.7-2.42.5-1.4
Water consumed over 24 hours0.60.82.91.7-1.2-0.8-0.80.8-0.8-0.8-0.5-1.0-0.1-0.5
Number of responses in last shaping day0.80.94.82.20.20.60.2-0.40.20.41.10.3-1.50.5