Hub : Genes

Ube3d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative polyA NM_001039610.1 0.31 0.25 3.1e-03 0.06 0.03 0.07 0.05 1.7e-03 1.3e-02 7.8e-04 3.0e-03
2 Adipose gene expression Ube3d 0.6 0.12 1.8e-14 0.04 0.14 0.13 0.12 3.0e-05 2.3e-15 2.1e-14 2.0e-13
3 BLA mRNA stability Ube3d 0.11 0.07 7.0e-06 0.06 0.06 0.09 0.09 3.6e-04 3.5e-04 2.5e-05 1.2e-05
4 PL gene expression Ube3d 0.18 0.09 0.0e+00 0.2 0.22 0.23 0.23 4.1e-22 2.2e-24 1.2e-24 1.7e-24
5 BLA gene expression Ube3d 0.19 0.12 9.5e-09 0.16 0.14 0.14 0.16 4.5e-09 3.7e-08 4.4e-08 3.5e-09
6 PL mRNA stability Ube3d 0.04 0.03 2.4e-03 0.03 0.02 0.02 0.02 3.0e-04 2.3e-03 1.3e-03 2.4e-03
7 Brain gene expression Ube3d 0.07 0.05 2.2e-06 0.06 0.04 0.06 0.06 1.4e-06 6.0e-05 5.7e-06 4.4e-06
8 LHb gene expression Ube3d 0.13 0.09 6.7e-03 0.09 0.03 0.01 0.02 3.5e-03 7.6e-02 2.0e-01 8.8e-02
9 NAcc gene expression Ube3d 0.24 0.11 3.5e-07 0.05 0.06 0.06 0.06 1.6e-06 1.4e-07 7.9e-08 1.1e-07
10 Liver gene expression Ube3d 0.58 0.12 0.0e+00 0.05 0.16 0.15 0.14 6.3e-06 3.1e-17 2.2e-16 9.9e-15
11 OFC gene expression Ube3d 0.25 0.17 7.8e-04 0.08 0.05 0.1 0.05 7.1e-03 2.3e-02 2.0e-03 2.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.83.05.20.30.82.2-2.21.9-2.3-1.6-1.6-1.5-2.0-1.6
Area under the delay curve4.85.110.3-0.22.2-2.92.2-2.72.02.62.63.21.21.3
BMI with tail0.20.51.00.8-0.4-0.61.0-0.60.80.70.70.70.80.6
BMI without tail0.20.40.7-0.70.6-0.40.8-0.70.30.70.70.5-0.60.2
Body weight0.10.31.21.1-0.70.5-0.20.5-0.1-0.4-0.40.00.4-0.4
Weight adjusted by age0.70.82.51.6-0.30.8-0.80.8-1.3-0.7-0.7-1.1-0.7-0.7
Bone surface3.46.010.20.70.23.0-3.12.7-3.2-2.4-2.4-2.5-2.6-2.2
Bone volume2.74.69.50.61.32.6-2.62.1-3.1-1.7-1.7-1.9-2.8-1.9
Breakpoint value in progressive ratio session1.01.12.1-1.5-1.11.1-1.01.2-0.8-1.2-1.2-0.6-0.2-0.9
Number of licking bursts0.50.63.61.9-0.90.5-0.50.5-0.2-0.5-0.5-0.8-0.1-0.1
Context. condit. distance diff. score1.51.82.6-0.4-0.61.6-1.61.5-1.4-1.5-1.5-1.6-1.1-1.1
Locomotion velocity, session 12.52.74.6-1.41.0-1.72.1-2.01.42.12.11.10.41.6
Locomotion distance, session 10.91.22.4-0.41.1-1.21.3-1.50.31.51.50.7-0.40.7
Locomotion velocity, session 22.83.25.90.70.4-2.42.2-2.31.82.12.11.81.21.5
Locomotion distance, session 20.91.32.8-0.41.2-1.41.3-1.70.21.51.51.1-0.60.6
Locomotion velocity, session 30.70.83.6-1.70.70.1-0.1-0.4-1.10.40.4-0.5-1.9-0.2
Locomotion distance, session 32.12.23.5-1.50.61.7-1.81.5-1.9-1.3-1.3-1.4-1.6-1.3
Stereotopy head waving bouts, day 30.20.31.3-0.3-0.4-0.30.5-0.21.10.20.20.30.70.4
Stereotopy head waving duration, day 31.92.34.1-0.4-0.0-1.82.0-2.01.91.71.71.40.71.4
Locomotion velocity, session 71.51.62.91.1-0.41.3-1.31.0-1.7-1.2-1.2-1.5-1.7-1.0
Locomotion distance, session 71.11.42.51.3-1.01.3-1.31.3-1.1-1.3-1.3-1.6-0.7-0.7
Stereotopy head waving bouts, day 71.11.32.6-0.51.2-1.11.3-1.40.61.61.60.8-0.40.9
Stereotopy head waving duration, day 70.50.61.1-0.50.7-0.70.8-1.00.41.01.00.3-0.60.6
Locomotion velocity, session 80.20.30.7-0.40.1-0.40.4-0.70.00.60.6-0.4-0.80.5
Locomotion distance, session 81.21.74.1-0.1-0.11.4-1.41.0-1.8-1.1-1.1-1.7-2.0-1.0
Degree of sensitization distance1.51.58.02.8-1.3-0.91.0-0.81.10.60.60.31.11.0
Degree of sensitization stereotypy0.91.01.9-0.61.3-1.01.0-1.20.31.41.40.7-0.50.7
Conditioned locomotion2.83.35.7-1.21.4-1.81.8-1.52.21.81.82.32.41.4
Cocaine response after cond. corrected1.92.14.00.10.4-1.81.8-2.01.22.02.01.20.31.4
Cocaine response after cond. not corrected1.41.53.0-0.30.4-1.51.6-1.71.01.71.71.10.11.0
Cocaine response before conditioning0.81.01.8-1.0-0.41.2-1.11.2-0.8-1.3-1.3-0.7-0.3-1.0
Saline control response0.81.02.60.4-0.2-1.31.1-1.00.90.70.71.61.60.3
Bone: connectivity density1.93.05.0-0.70.22.2-2.22.0-2.1-1.6-1.6-1.9-1.7-1.4
Bone: cortical apparent density8.511.316.3-1.92.3-3.93.9-4.03.34.04.04.02.12.1
Bone: cortical area0.30.41.9-0.81.4-0.30.3-0.6-0.30.70.70.7-0.6-0.3
Bone: cortical porosity0.30.30.60.50.10.6-0.80.8-0.5-0.6-0.6-0.2-0.4-0.5
Bone: cortical porosity0.20.20.60.10.50.6-0.70.7-0.5-0.4-0.4-0.1-0.5-0.5
Bone: cortical thickness0.81.42.8-1.21.7-1.01.2-1.30.51.51.51.3-0.10.4
Bone: cortical thickness2.73.16.3-0.30.7-2.22.3-2.51.22.32.31.80.31.4
Bone: cortical tissue density8.811.616.7-1.92.2-4.04.0-4.03.44.14.14.12.22.2
Condit. Reinf. active minus inactive responses0.50.54.72.2-0.60.1-0.20.3-0.2-0.3-0.30.10.6-0.3
Condit. Reinf. active-inactive response ratio1.21.37.32.7-1.2-1.10.8-0.70.70.40.40.91.40.3
Condit. Reinf. active responses0.10.11.41.2-0.10.0-0.10.1-0.0-0.1-0.10.20.3-0.2
Condit. Reinf. inactive responses0.30.41.6-1.31.20.5-0.20.2-0.20.10.1-0.2-0.8-0.1
Incentive salience index mean0.70.83.82.0-1.4-0.70.5-0.30.60.00.00.51.30.3
Condit. Reinf. lever presses1.01.33.40.8-1.8-1.31.1-0.91.40.40.40.91.80.7
Condit. Reinf. active minus inactive responses0.91.12.6-1.10.51.3-1.00.8-1.5-0.8-0.8-0.8-1.6-1.0
Condit. Reinf. active-inactive response ratio1.41.52.9-0.4-0.21.7-1.31.3-1.4-1.1-1.1-1.4-1.5-1.0
Condit. Reinf. active responses1.11.54.2-1.31.41.2-1.10.6-1.8-0.6-0.6-0.4-2.0-1.2
Condit. Reinf. inactive responses0.70.94.5-0.82.10.3-0.50.0-1.1-0.0-0.00.4-1.5-0.8
Condit. Reinf. lever presses0.30.54.1-2.00.60.10.0-0.0-0.40.10.10.2-0.6-0.2
Condit. Reinf. lever reinforcers received1.01.54.3-1.61.51.0-0.90.5-1.7-0.4-0.4-0.3-2.1-1.1
Conditioned reinforcement - actives3.83.87.6-1.91.92.2-1.91.7-2.8-1.4-1.4-1.0-2.6-1.9
Conditioned reinforcement - inactives1.01.12.6-0.81.01.2-1.00.9-1.5-0.7-0.7-0.6-1.6-0.9
Conditioned locomotion1.51.83.10.30.71.8-1.61.7-1.6-1.3-1.3-0.9-1.3-1.3
Patch foraging indifference point 0 sec0.91.42.8-1.50.61.7-1.31.5-0.7-1.3-1.3-0.9-0.5-1.0
Patch foraging indifference point AUC1.11.34.81.7-2.20.5-0.81.00.1-1.4-1.4-0.80.0-0.5
Delay disc. indifference point, 0s delay1.41.53.2-0.91.5-1.51.1-1.40.81.31.31.80.50.6
Delay disc. indifference point, 16s delay3.43.46.10.31.1-2.51.9-2.21.82.22.22.41.41.3
Delay disc. indifference point, 2s delay1.21.36.10.12.5-1.00.5-1.10.11.11.11.6-0.60.1
Delay disc. indifference point, 24s delay3.23.15.90.61.6-2.11.9-2.01.62.02.02.41.41.0
Delay disc. indifference point, 4s delay0.20.31.2-0.4-0.3-0.70.1-0.50.60.00.01.10.5-0.2
Delay disc. indifference point, 8s delay4.95.09.5-1.42.8-2.72.0-2.71.72.62.63.10.51.0
Indifference point function ln k1.01.46.4-2.42.5-0.20.3-0.5-0.50.90.90.8-0.6-0.0
Indifference point function log k1.01.46.4-2.42.5-0.20.3-0.5-0.50.90.90.8-0.6-0.0
Patch foraging total patch changes 0 sec1.21.93.8-1.71.01.9-1.51.7-0.9-1.5-1.5-1.0-0.8-1.2
Patch foraging total patch changes 12 sec0.60.84.9-2.2-0.30.9-0.50.90.4-0.8-0.8-0.60.0-0.3
Patch foraging total patch changes 18 sec1.72.13.81.2-1.81.5-1.41.7-0.4-2.0-2.0-1.7-0.5-0.8
Patch foraging total patch changes 24 sec2.42.95.11.7-2.31.8-1.51.8-0.9-2.3-2.3-1.8-0.4-1.1
Patch foraging total patch changes 6 sec3.95.89.9-0.1-1.52.9-2.93.0-1.9-3.1-3.1-2.6-1.2-2.0
Patch foraging time to switch 0 sec1.32.03.40.5-1.3-1.81.7-1.71.31.71.70.60.91.6
Patch foraging water rate 0 sec1.32.14.4-0.60.52.1-1.82.0-0.9-1.9-1.9-0.8-0.3-1.4
Patch foraging water rate 12 sec0.91.42.9-1.01.71.7-1.01.3-1.5-0.5-0.5-1.2-1.4-0.6
Patch foraging water rate 18 sec0.30.41.3-1.10.10.5-0.50.3-0.9-0.6-0.6-0.0-0.5-0.9
Patch foraging water rate 24 sec1.31.84.8-2.21.91.7-1.21.3-1.4-0.9-0.9-0.7-1.0-0.9
Patch foraging water rate 6 sec0.91.35.3-1.62.31.1-0.70.6-1.1-0.2-0.2-0.2-1.6-0.8
Seeking ratio, delayed vs. immediate footshock0.80.95.2-2.3-0.20.7-0.70.7-0.8-0.4-0.4-1.2-0.8-0.2
Distance traveled before self-admin0.20.30.7-0.8-0.70.3-0.30.2-0.6-0.2-0.2-0.7-0.7-0.3
Distance traveled after self-admin0.30.42.2-1.5-0.80.5-0.20.3-0.4-0.4-0.4-0.4-0.4-0.4
Extensor digitorum longus weight0.10.41.31.0-1.1-0.40.4-0.10.8-0.1-0.10.41.10.2
Bone: elastic displacement0.60.73.1-1.5-0.7-0.10.30.31.3-0.1-0.10.51.80.3
Bone: elastic work1.11.45.5-2.4-0.4-0.80.9-0.41.70.50.51.01.90.7
Bone: endosteal estimation1.02.23.51.2-0.91.7-1.91.7-1.7-1.7-1.7-1.2-0.8-1.4
Bone: endosteal perimeter0.40.81.80.70.31.1-1.10.9-1.3-0.7-0.7-0.4-0.8-1.1
Epididymis fat weight0.61.33.2-1.1-0.61.7-1.01.8-0.4-1.5-1.5-0.80.4-0.7
Delta time in closed arm before/after self-admin0.70.61.80.30.4-0.50.7-0.41.30.60.61.31.40.5
Delta time in open arm before/after self-admin3.23.127.30.7-5.2-0.2-0.10.20.8-0.9-0.9-1.51.30.4
Diff in mean of infusions in LGA sessions0.91.03.8-2.01.00.9-0.90.9-0.8-0.7-0.70.1-0.9-1.0
Delay discount exponential model param4.64.99.20.2-2.02.8-2.22.7-2.0-2.5-2.5-3.0-1.1-1.3
Extinction: sum of active levers before priming0.20.20.3-0.10.5-0.40.5-0.40.60.60.60.40.10.4
Active lever presses in extinction session 60.70.71.61.20.70.8-0.80.5-1.1-0.3-0.3-0.8-1.3-0.8
Bone: final force0.10.10.50.70.1-0.10.1-0.2-0.30.30.30.2-0.2-0.2
Bone: final moment0.10.10.60.8-0.10.0-0.0-0.1-0.30.10.10.2-0.1-0.3
Food consumed during 24 hour testing period0.20.20.60.80.70.0-0.3-0.1-0.5-0.1-0.10.5-0.5-0.5
Glucose0.30.51.4-0.50.10.8-0.90.6-1.2-0.5-0.5-0.6-1.0-0.7
Heart weight1.01.44.4-0.40.71.2-1.10.7-1.9-0.8-0.8-0.8-2.1-1.0
Delay discount hyperbolic model param3.63.88.00.2-1.82.6-1.92.4-1.7-2.2-2.2-2.8-0.9-1.1
Intermittent access intake day 1-15 change5.35.321.04.6-0.41.8-2.21.8-2.6-2.0-2.0-1.6-2.1-1.9
Intermittent access intake escalation5.04.927.25.2-0.51.5-1.91.4-2.3-1.6-1.6-1.5-2.0-1.5
Intermittent access intake escalation 24.84.717.74.2-1.11.8-2.32.0-2.2-2.0-2.0-1.8-1.6-1.6
Intermitt. access day 1 inactive lever presses0.30.31.1-0.41.0-0.00.3-0.4-0.10.60.6-0.2-0.80.5
Intermitt. access day 15 inactive lever presses0.70.82.6-1.21.6-0.20.3-0.7-0.40.60.60.8-1.5-0.4
Intermitt. access escalation Index0.50.51.0-1.00.30.9-0.70.8-0.7-0.7-0.7-0.6-0.6-0.4
Intermittent access day 1 total infusions0.10.10.4-0.60.3-0.20.4-0.30.00.40.4-0.1-0.20.1
Intermittent access day 15 total infusions2.93.210.93.3-0.71.5-1.71.4-2.0-1.4-1.4-1.7-1.9-1.4
Intermittent access terminal intake (last 3 days)4.24.610.83.3-1.02.1-2.22.0-2.4-1.9-1.9-2.3-2.0-1.8
Intermittent access total infusions1.31.43.21.3-0.11.4-1.21.2-1.4-0.9-0.9-1.8-1.5-0.8
Intermittent access day 1 locomotion0.30.31.0-1.00.9-0.40.4-0.40.20.60.60.40.00.1
Intermittent access day 15 total locomotion0.40.41.8-0.21.3-0.10.0-0.3-0.80.60.6-0.1-1.1-0.0
Intermittent access total locomotion0.70.71.9-0.51.40.9-0.80.7-1.2-0.3-0.3-0.7-1.3-0.7
Intermittent access standard deviation1.31.38.02.81.20.5-0.60.3-1.10.20.2-0.7-1.5-0.2
Left kidney weight0.51.56.1-1.6-2.5-0.60.9-0.31.6-0.0-0.00.41.70.8
Right kidney weight0.41.02.3-1.2-1.51.0-0.81.1-0.1-1.2-1.2-1.1-0.1-0.4
Cocaine induced anxiety0.20.21.81.30.30.2-0.20.1-0.2-0.0-0.0-0.2-0.4-0.1
Post-drug Anxiety0.00.10.20.20.50.1-0.1-0.1-0.30.10.10.2-0.3-0.2
Baseline Anxiety0.30.31.3-1.0-1.2-0.60.2-0.30.40.00.00.50.70.1
Tail length0.10.40.5-0.5-0.40.7-0.60.6-0.4-0.7-0.7-0.6-0.6-0.7
Length with tail0.30.91.7-0.80.11.3-1.31.1-0.9-1.1-1.1-0.7-0.5-1.0
Length without tail0.30.51.21.1-0.90.7-0.80.8-0.3-0.9-0.9-0.30.6-0.4
Times rat made contact with spout1.41.64.3-1.42.1-1.00.9-1.50.01.51.51.3-1.00.2
Lifetime Intake1.21.33.1-0.10.71.5-1.11.1-1.5-0.7-0.7-1.7-1.8-0.8
Liver weight, left0.71.14.7-0.22.2-0.70.6-1.10.11.21.21.0-1.00.2
Liver weight, right1.22.03.1-1.3-0.6-1.71.7-1.61.41.51.51.31.41.1
Locomotor activity1.52.44.5-1.31.12.1-1.81.7-1.8-1.5-1.5-1.2-1.5-1.3
Locomotor testing distance1.11.93.9-2.01.61.7-1.41.3-1.3-1.1-1.1-0.4-1.2-1.2
Locomotor testing rearing0.71.14.9-1.82.20.7-0.60.2-0.9-0.1-0.10.8-1.0-1.0
Locomotion in novel chamber0.91.14.3-1.0-2.1-0.81.1-0.91.20.70.7-0.40.51.1
Locomotion in novel chamber post-restriction0.91.02.2-1.2-0.7-1.11.5-1.21.11.01.00.80.50.8
Fecal boli incidents, locomotor time 10.20.30.8-0.2-0.0-0.80.6-0.8-0.10.30.30.9-0.1-0.1
Change in fecal boli incidents, locomotor task0.10.11.01.0-0.5-0.00.1-0.1-0.00.30.3-0.3-0.10.2
Time >=10cm from walls, locomotor time 10.40.42.61.60.3-0.60.3-0.6-0.00.50.50.1-0.00.5
Bouts of movement, locomotor time 11.82.06.3-2.50.7-1.11.6-1.21.41.51.50.91.11.2
Total resting periods, locomotor time 11.71.97.3-2.70.6-1.01.5-1.11.31.41.40.81.11.2
Rest time, locomotor task time 18.39.113.8-1.12.4-3.43.6-3.62.63.73.73.71.82.1
Distance moved, locomotor task time 112.113.221.14.6-3.63.7-3.83.8-2.9-4.1-4.1-4.3-1.6-2.1
Vertical activity count, locomotor time 18.79.125.33.9-5.02.3-2.82.7-1.6-3.6-3.6-3.0-0.2-1.5
Time >=10cm from walls, locomotor time 20.20.20.5-0.70.6-0.20.4-0.30.10.70.7-0.4-0.20.7
Bouts of movement, locomotor time 21.11.16.6-2.61.9-0.20.4-0.40.10.70.70.9-0.30.0
Total resting periods, locomotor time 21.81.98.0-2.82.4-0.70.9-1.00.41.21.21.5-0.10.2
Rest time, locomotor task time 28.59.816.3-0.31.6-4.03.8-3.73.13.63.63.92.42.1
Distance moved, locomotor task time 29.210.620.52.7-2.93.8-3.53.6-2.9-3.6-3.6-4.5-2.1-1.7
Vertical activity count, locomotor time 26.67.210.32.9-2.92.9-2.72.6-2.3-3.0-3.0-3.2-1.7-1.5
Light reinforcement 10.20.42.21.5-0.80.4-0.30.60.1-0.6-0.6-0.30.8-0.2
Light reinforcement 22.43.17.92.3-1.7-1.81.7-1.12.51.11.10.82.81.5
Bone: marrow area0.92.03.11.1-1.11.6-1.81.6-1.6-1.6-1.6-1.2-0.7-1.3
Bone: maximum diameter0.30.61.8-1.11.30.5-0.40.1-1.10.10.1-0.0-1.3-0.7
Bone: maximum force0.10.21.40.6-1.2-0.20.1-0.00.2-0.1-0.1-0.10.50.1
Bone: maximum moment0.10.21.60.6-1.3-0.20.1-0.00.3-0.1-0.1-0.00.70.1
Mean time between licks in bursts0.40.61.90.4-0.6-0.40.7-0.21.30.70.7-0.11.40.9
Mean num. licks in bursts1.92.38.7-3.02.1-1.21.0-1.50.21.41.41.7-0.60.3
Cd content in liver0.70.77.2-2.70.20.2-0.10.40.4-0.2-0.2-0.10.50.3
Co content in liver1.31.53.1-1.70.6-1.11.3-0.81.60.90.91.51.80.9
Cu content in liver0.30.31.1-1.00.80.5-0.40.4-0.90.10.1-0.3-0.8-0.2
Fe content in liver3.54.27.30.71.52.6-2.42.2-2.7-1.7-1.7-2.0-2.6-1.5
K content in liver0.80.82.31.01.5-0.80.7-0.80.01.11.11.0-0.40.3
Mg content in liver1.51.52.70.51.3-1.61.3-1.50.61.61.61.40.20.8
Mn content in liver0.20.20.60.80.3-0.30.1-0.00.30.10.10.80.8-0.1
Na content in liver1.41.413.63.7-0.60.4-0.40.7-0.1-0.5-0.5-0.40.3-0.3
Rb content in liver1.01.24.9-1.40.90.8-0.80.4-1.6-0.6-0.6-0.7-2.2-0.8
Se content in liver2.02.44.01.20.52.0-2.02.0-1.7-1.6-1.6-1.6-1.3-1.0
Sr content in liver2.22.08.31.3-2.90.8-0.91.30.1-1.8-1.8-0.81.4-0.6
Zn content in liver0.30.31.50.41.2-0.1-0.2-0.1-0.80.30.30.5-0.5-0.3
Bone: minimum diameter0.91.72.7-0.81.31.6-1.61.4-1.6-1.0-1.0-0.5-1.3-1.4
Time in familiar zone, hab. session 11.71.63.2-1.30.61.8-1.41.6-1.1-1.3-1.3-1.2-0.8-0.9
Time in novel zone, hab. session 10.90.81.40.20.8-1.11.0-1.00.61.21.21.10.60.6
Total zone transitions, hab. session 10.40.61.8-1.21.3-0.20.6-0.60.41.01.0-0.0-0.50.7
Total locomotion distance, hab. session 10.50.71.9-0.91.4-0.40.6-0.90.01.11.10.1-1.20.5
Locomotion velocity, hab. session 11.01.42.7-1.41.1-1.21.3-1.60.71.51.50.7-0.70.9
Time in familiar zone, hab. session 21.81.98.8-3.02.10.8-0.60.1-1.00.10.1-0.4-2.2-0.6
Time in novel zone, hab. session 21.11.14.32.1-0.8-0.90.8-0.50.80.40.40.91.70.6
Total zone transitions, hab. session 20.20.20.5-0.3-0.7-0.40.5-0.60.20.50.5-0.6-0.20.6
Total locomotion distance, hab. session 20.20.31.5-0.30.2-0.30.3-0.7-0.50.60.6-0.4-1.20.2
Locomotion velocity, hab. session 20.20.30.7-0.1-0.2-0.50.5-0.9-0.20.60.6-0.3-0.80.3
Novel to familiar place preference ratio3.53.66.32.5-1.71.9-2.22.3-1.7-2.1-2.1-2.0-0.3-1.1
Novelty place preference2.62.65.22.3-1.31.5-1.91.9-1.5-1.8-1.8-1.6-0.3-1.0
Time in novel zone, NPP test1.92.03.82.0-1.01.3-1.71.6-1.4-1.5-1.5-1.4-0.4-0.9
Total zone transitions, NPP test1.42.04.2-0.31.4-1.61.6-2.00.62.02.00.9-0.61.0
Total locomotion distance, NPP test0.70.91.9-0.11.3-0.80.9-1.4-0.11.31.30.4-1.10.5
Locomotion velocity, NPP test0.40.61.50.21.1-0.50.7-1.1-0.41.01.00.1-1.20.3
Intraocular pressure1.42.012.3-1.73.5-0.30.8-0.60.61.41.40.90.20.6
Delta distance traveled before/after self-admin0.30.30.5-0.70.00.7-0.50.7-0.3-0.7-0.70.10.2-0.6
Delta ambulatory time before/after self-admin0.30.30.5-0.50.60.7-0.60.7-0.3-0.6-0.60.20.1-0.6
Parametrial fat weight0.71.42.8-1.7-0.11.4-1.41.3-0.4-1.5-1.5-0.8-0.9-1.1
Pavlov. Cond. lever latency1.51.910.0-3.22.20.7-0.50.2-1.30.30.3-0.2-1.9-0.5
Pavlov. Cond. magazine entry latency0.50.74.30.4-0.6-0.50.10.11.2-0.2-0.20.92.10.2
Pavlov. Cond. change in total contacts1.41.54.31.8-2.10.6-0.91.20.1-1.5-1.5-0.61.3-0.4
Pavlov. Cond. index score0.91.24.41.6-1.6-0.70.3-0.21.3-0.3-0.30.82.10.3
Pavlov. Cond. latency score0.81.13.81.9-1.3-0.70.4-0.21.2-0.1-0.10.71.80.3
Pavlov. Cond. lever contacts1.41.67.72.8-1.8-0.90.5-0.41.2-0.1-0.10.61.90.4
Pavlov. Cond. magazine entry number1.41.76.80.90.61.3-0.90.7-2.0-0.5-0.5-1.7-2.6-0.7
Pavlov. Cond. intertrial magazine entries3.54.28.62.10.72.2-2.11.7-2.9-1.6-1.6-2.2-2.9-1.6
Pavlov. Cond. lever-magazine prob. diff.0.91.14.61.4-1.7-0.60.10.01.2-0.4-0.40.62.20.2
Pavlov. Cond. response bias1.21.45.71.0-1.2-1.20.7-0.61.70.30.31.32.40.6
Pavlov. Cond. lever latency0.00.00.2-0.1-0.20.2-0.20.2-0.1-0.1-0.1-0.40.00.1
Pavlov. Cond. magazine entry latency0.20.21.0-0.81.00.10.1-0.1-0.30.20.20.2-0.5-0.1
Pavlov. Cond. change in total contacts0.30.52.2-1.50.8-0.20.2-0.5-0.20.50.50.5-1.1-0.3
Pavlov. Cond. index score0.10.20.5-0.40.7-0.20.4-0.40.10.40.40.5-0.20.1
Pavlov. Cond. latency score0.20.20.5-0.40.6-0.50.6-0.60.20.50.50.7-0.10.1
Pavlov. Cond. lever contacts0.30.41.1-0.10.4-0.70.8-0.80.70.70.71.10.40.3
Pavlov. Cond. magazine entry number0.10.10.70.2-0.4-0.10.00.20.3-0.1-0.1-0.00.90.2
Pavlov. Cond. intertrial magazine entries1.01.42.50.3-1.41.2-1.31.5-0.4-1.6-1.6-1.40.1-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.50.6-0.20.4-0.30.20.30.30.4-0.20.1
Pavlov. Cond. response bias0.10.20.6-0.60.8-0.10.3-0.30.10.30.30.5-0.3-0.1
Time in closed arm before self-admin0.80.97.7-2.80.80.4-0.40.2-0.6-0.3-0.30.0-1.0-0.5
Time in closed arm after self-admin1.31.33.8-2.01.71.2-1.11.0-0.8-0.8-0.8-0.2-1.2-0.8
Time in open arm before self-admin2.22.45.72.41.11.6-1.81.5-1.5-1.3-1.3-1.0-1.5-1.4
Time in open arm after self-admin1.81.911.82.5-3.40.1-0.30.40.4-0.7-0.7-1.20.90.0
Bone: periosteal estimation0.51.12.40.40.01.3-1.31.1-1.6-1.0-1.0-0.6-1.1-1.3
Bone: periosteal perimeter0.50.82.3-0.61.50.8-0.90.5-1.3-0.3-0.30.2-1.0-1.1
Bone: post-yield work1.11.53.80.9-1.91.0-1.11.0-1.1-1.4-1.4-1.7-0.7-0.5
Progressive ratio test 1 active lever presses1.21.21.9-1.21.31.4-1.11.2-1.3-0.7-0.7-1.0-1.2-0.9
Progressive ratio test 1 breakpoint1.11.11.9-1.41.31.3-1.01.1-1.2-0.6-0.6-0.8-1.1-0.9
Progressive ratio test 1 inactive lever presses2.22.413.5-3.73.30.40.30.10.30.60.60.9-0.3-0.1
Progressive ratio test 2 active lever presses3.74.07.71.00.72.1-2.42.0-2.8-2.0-2.0-1.5-2.2-2.3
Progressive ratio test 2 breakpoint3.94.48.30.70.92.4-2.52.2-2.9-2.0-2.0-1.8-2.3-2.4
Progressive ratio test 2 inactive lever presses2.12.49.1-1.23.01.3-1.10.9-2.2-0.4-0.4-0.3-2.2-1.4
Incentive Sensitization - Responses7.27.312.63.6-0.02.7-3.02.6-3.4-2.7-2.7-2.2-2.5-2.7
Incentive Sensitization - Breakpoint7.17.212.03.5-0.12.7-3.02.6-3.4-2.7-2.7-2.2-2.5-2.7
Sum of active levers in priming session hrs 5-60.50.53.6-0.21.9-0.10.2-0.3-0.20.70.70.5-0.4-0.0
Progressive ratio0.60.62.01.01.40.4-0.90.4-0.8-0.4-0.40.4-0.9-1.0
Food seeking constrained by brief footshock0.80.92.7-1.40.80.7-0.90.5-1.3-0.2-0.2-1.2-1.6-0.2
Seeking ratio, punishment vs. effort0.60.73.2-1.8-1.5-0.00.4-0.20.10.20.2-1.00.00.9
Retroperitoneal fat weight0.41.35.0-2.22.01.1-0.50.5-1.10.20.20.1-1.4-0.4
Reaction time number correct0.91.31.9-0.50.31.2-1.31.1-1.4-1.3-1.3-0.7-1.1-1.4
Reaction time mean minus median0.60.82.10.5-0.7-1.51.0-1.40.60.90.91.00.20.4
Reaction time mean minus median AUC0.50.61.80.20.2-1.20.9-1.40.21.01.00.8-0.30.3
Reaction time num false alarms2.94.06.62.20.82.6-2.22.2-2.2-1.9-1.9-1.8-2.1-1.5
Reaction time num false alarms AUC2.63.66.61.90.12.6-2.02.3-1.8-2.1-2.1-1.8-1.6-1.4
Reaction time trials correct on left0.91.31.9-0.50.31.2-1.31.1-1.4-1.3-1.3-0.7-1.1-1.4
Reaction time trials on left0.91.32.0-0.60.21.3-1.41.1-1.4-1.3-1.3-0.7-1.2-1.4
Reaction time mean1.11.53.2-0.50.1-1.61.6-1.80.71.81.80.7-0.21.0
Reaction time mean AUC0.70.92.00.2-0.3-1.31.3-1.40.51.41.40.3-0.20.9
Median of all reaction times1.11.53.2-0.5-0.1-1.41.7-1.70.71.81.80.4-0.21.2
Reaction time omissions0.40.64.7-2.2-0.30.3-0.20.10.1-0.2-0.2-0.8-0.80.1
Reaction time false alarm rate1.11.53.21.80.21.7-1.21.5-1.0-1.2-1.2-1.3-1.0-0.6
Reaction time premature initiation rate0.81.12.6-1.61.11.3-1.21.2-0.7-0.8-0.8-0.4-0.6-0.9
Reaction time premature initiations1.21.73.3-1.81.51.5-1.51.3-1.2-1.1-1.1-0.5-1.1-1.3
Std. dev. reaction times0.60.81.80.30.2-1.21.1-1.30.41.31.30.6-0.30.7
Reaction time trials completed0.91.32.0-0.60.21.3-1.41.1-1.4-1.3-1.3-0.7-1.2-1.4
Reaction time trials AUC1.11.62.4-0.70.21.4-1.51.2-1.6-1.4-1.4-0.9-1.3-1.5
Run reversals in cocaine runway, females1.31.26.02.5-2.0-0.50.3-0.10.8-0.1-0.10.01.40.7
Run reversals in cocaine runway, males1.41.45.62.4-0.80.6-1.20.9-1.0-1.3-1.3-0.3-0.2-1.3
Latency to leave start box in cocaine runway2.12.38.90.6-3.0-2.01.3-1.31.30.60.61.02.11.0
Latency to leave start box in cocaine runway, F1.01.15.22.2-2.3-0.70.1-0.20.2-0.4-0.40.11.20.2
Latency to leave start box in cocaine runway, M4.24.16.1-2.5-2.3-2.42.2-2.22.21.71.71.11.71.8
Std. dev. time between licks in bursts1.31.67.71.6-1.5-0.40.80.11.80.00.00.42.80.7
Total sessions with >9 infusions1.61.811.1-3.31.41.4-0.91.1-0.9-0.7-0.7-0.6-0.6-0.6
Short access day 1 total inactive lever presses1.21.37.7-1.62.80.10.5-0.3-0.21.21.20.4-0.60.6
Short access day 10 total inactive lever presses1.01.13.0-0.6-0.5-0.91.2-0.71.60.70.70.51.71.2
Short access day 1 total infusions3.33.518.5-4.04.30.50.2-0.00.11.21.20.5-0.40.4
Short access day 10 total infusions0.10.10.3-0.5-0.00.4-0.10.2-0.1-0.2-0.2-0.2-0.3-0.4
Short access total infusions1.01.14.1-2.01.71.1-0.60.6-0.9-0.1-0.1-0.7-1.2-0.5
Short access day 1 locomotion3.13.413.5-3.03.7-1.01.1-1.40.01.71.72.0-0.50.2
Short access day 10 total locomotion1.31.46.5-2.52.60.10.3-0.4-0.40.90.90.3-1.00.0
Short access total locomotion1.31.36.1-2.52.30.3-0.0-0.2-0.90.50.50.1-1.3-0.3
One hour access (0.3 mA shock)4.65.312.80.92.02.6-2.42.0-3.6-1.4-1.4-2.2-3.4-2.1
Compulsive drug intake0.50.51.50.21.00.7-0.90.6-1.2-0.3-0.3-0.3-0.8-0.4
One hour access (shock baseline)1.21.33.61.10.31.2-0.90.8-1.6-0.8-0.8-1.5-1.9-1.1
Social response proportion0.80.82.8-1.5-1.4-0.40.30.11.3-0.3-0.30.21.70.4
Social responses0.91.24.3-2.10.7-0.70.9-0.41.60.60.61.31.40.4
Social time0.60.73.8-2.00.8-0.50.6-0.50.80.20.21.20.7-0.2
Soleus weight1.75.09.42.0-1.82.4-2.62.9-1.4-3.1-3.1-1.9-0.0-1.6
Bone: stiffness0.20.31.21.1-0.1-0.10.1-0.4-0.60.30.3-0.5-1.10.1
Tibialis anterior weight0.30.98.62.9-0.80.1-0.10.20.3-0.4-0.4-0.00.6-0.1
Time to tail flick, vehicle, before self-admin0.60.75.0-0.32.20.4-0.50.3-0.8-0.0-0.00.1-0.9-0.5
Time to tail flick, vehicle, after self-admin0.40.42.8-1.70.5-0.60.1-0.3-0.0-0.1-0.10.80.1-0.2
Time to tail flick, test, before self-admin0.50.52.01.4-0.30.6-0.60.6-0.7-0.7-0.7-0.4-0.3-0.8
Time to tail flick, test, after self-admin0.70.85.32.30.40.3-0.50.3-0.9-0.4-0.4-0.4-1.0-0.4
Delta time to tail flick, vehicle, before/after SA1.41.32.6-1.6-0.3-1.41.4-1.31.11.11.10.90.71.1
Delta time to tail flick, test, before/after SA0.10.10.20.40.2-0.20.3-0.20.10.20.20.30.00.3
Tibia length0.92.43.8-1.6-1.6-1.71.8-1.41.81.41.41.32.01.1
Ambulatory time before self-admin0.50.65.0-0.7-2.2-0.30.3-0.20.3-0.0-0.0-0.60.20.3
Ambulatory time after self-admin0.30.42.8-0.7-1.7-0.10.3-0.10.4-0.1-0.10.10.70.1
Bone: tissue strength0.20.20.6-0.8-0.80.3-0.40.50.0-0.4-0.4-0.30.4-0.3
Total heroin consumption0.10.10.40.5-0.70.1-0.30.1-0.2-0.3-0.30.3-0.1-0.6
Bone: trabecular number1.82.84.70.20.82.2-2.21.9-2.1-1.6-1.6-1.5-1.7-1.6
Bone: trabecular spacing2.63.46.1-1.40.6-2.32.4-2.51.42.32.31.60.61.6
Bone: trabecular thickness0.91.01.60.90.71.3-1.21.0-1.2-0.9-0.9-0.8-1.3-0.8
Bone: trabecular tissue density3.65.09.2-3.0-0.3-2.42.6-2.22.91.71.72.32.61.6
Water consumed over 24 hours1.01.22.6-1.61.4-0.90.9-1.00.71.01.01.60.20.2
Number of responses in last shaping day0.70.74.0-0.62.00.1-0.6-0.1-0.8-0.1-0.10.4-1.3-0.8