Hub : Genes

U2af1l4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression U2af1l4 0.15 0.1 6.1e-03 -0 0.01 0 -0.01 4.2e-01 1.7e-01 2.6e-01 9.0e-01
2 NAcc alternative TSS NM_001008775.2 0.1 0.09 9.6e-06 0.05 0.04 0.04 0.05 1.7e-06 1.2e-05 1.4e-05 2.2e-06
3 NAcc gene expression U2af1l4 0.03 0.02 1.3e-04 0.02 0.03 0.03 0.02 2.2e-03 4.0e-04 3.9e-04 8.5e-04
4 PL alternative TSS XM_039081942.1 0.06 0.04 8.4e-06 0.03 0.04 0.03 0.04 3.7e-04 1.0e-05 1.7e-04 4.0e-05
5 NAcc alternative TSS XM_039081942.1 0.03 0.02 1.8e-04 0.02 0.04 0.04 0.03 1.5e-03 5.8e-05 2.5e-05 1.1e-04
6 Liver isoform ratio XM_039081944.1 0.06 0.05 9.6e-03 0 0.01 0 0.01 2.7e-01 4.9e-02 9.7e-02 5.6e-02
7 Brain gene expression U2af1l4 0.13 0.08 6.7e-08 0.1 0.08 0.07 0.09 2.4e-09 5.2e-08 2.0e-07 5.6e-09
8 BLA gene expression U2af1l4 0.4 0.18 3.8e-03 0.01 0.02 0.07 0.04 6.9e-02 4.2e-02 1.9e-04 3.0e-03
9 pVTA intron excision ratio chr1_85817295_85817468 0.17 0.12 6.6e-03 -0 0.04 0.03 0.02 3.5e-01 5.6e-03 1.7e-02 3.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.11.82.9-1.5-1.71.7-1.60.6-1.01.7-0.1-1.3
Area under the delay curve0.50.61.50.20.6-0.20.50.21.2-0.9-1.01.1
BMI with tail0.20.50.90.90.5-1.00.9-0.50.1-0.9-0.50.7
BMI without tail0.00.10.2-0.2-0.00.3-0.20.4-0.10.30.1-0.4
Body weight1.66.712.5-3.5-2.43.4-3.42.6-0.22.7-1.8-1.1
Weight adjusted by age0.20.20.5-0.5-0.70.6-0.50.4-0.30.5-0.5-0.2
Bone surface0.61.12.6-1.5-0.81.6-1.40.40.51.0-0.8-0.0
Bone volume0.91.53.3-1.7-1.21.8-1.70.50.01.4-0.7-0.4
Breakpoint value in progressive ratio session0.60.62.0-0.40.10.2-0.10.51.3-0.6-1.40.9
Number of licking bursts3.33.96.02.32.4-2.12.3-1.91.2-2.20.91.8
Context. condit. distance diff. score0.60.71.70.50.4-0.60.6-0.21.0-0.9-1.31.3
Locomotion velocity, session 10.50.51.60.2-0.10.0-0.1-0.9-1.20.61.2-0.9
Locomotion distance, session 10.30.41.0-0.40.30.5-0.3-1.00.9-0.1-0.50.8
Locomotion velocity, session 21.21.35.30.91.2-0.70.7-1.9-0.0-0.32.3-0.2
Locomotion distance, session 22.84.011.81.82.2-1.71.7-3.41.2-1.81.61.6
Locomotion velocity, session 30.60.72.60.50.9-0.40.4-1.60.2-0.31.30.2
Locomotion distance, session 31.41.56.3-0.61.00.3-0.2-0.92.5-0.7-1.41.7
Stereotopy head waving bouts, day 31.01.24.30.0-0.90.1-0.20.4-2.10.91.2-1.8
Stereotopy head waving duration, day 31.01.24.70.5-0.9-0.20.20.2-2.20.61.5-1.7
Locomotion velocity, session 70.40.51.4-0.10.5-0.10.1-0.61.2-0.5-0.91.1
Locomotion distance, session 70.10.10.5-0.40.10.2-0.4-0.70.30.30.50.2
Stereotopy head waving bouts, day 71.61.73.21.51.8-1.41.5-1.01.0-1.50.51.2
Stereotopy head waving duration, day 71.21.53.01.71.2-1.71.7-0.9-0.0-1.30.50.6
Locomotion velocity, session 83.64.36.92.52.2-2.42.4-2.60.9-2.20.81.6
Locomotion distance, session 82.63.86.61.72.2-1.81.8-2.62.0-2.10.42.3
Degree of sensitization distance0.80.82.2-0.1-0.70.2-0.40.8-1.50.91.2-1.2
Degree of sensitization stereotypy2.52.74.81.82.2-1.71.8-1.21.4-1.90.31.7
Conditioned locomotion0.60.71.31.10.6-1.11.2-0.40.3-1.1-0.20.7
Cocaine response after cond. corrected1.01.12.8-0.4-1.10.4-0.51.2-1.71.00.1-1.6
Cocaine response after cond. not corrected1.92.15.3-0.8-1.30.8-1.01.3-2.11.70.9-2.3
Cocaine response before conditioning0.80.91.9-1.3-0.11.4-1.30.40.21.21.0-0.8
Saline control response0.20.20.5-0.3-0.50.2-0.4-0.1-0.70.60.6-0.7
Bone: connectivity density0.20.30.8-0.7-0.60.9-0.7-0.1-0.10.70.2-0.5
Bone: cortical apparent density1.21.62.91.61.1-1.71.5-1.70.1-1.30.11.0
Bone: cortical area0.81.32.3-1.5-1.21.5-1.50.9-0.31.3-0.5-0.8
Bone: cortical porosity3.84.18.82.03.0-1.82.1-2.11.6-2.21.51.5
Bone: cortical porosity4.75.110.42.23.2-2.12.3-2.41.8-2.41.51.8
Bone: cortical thickness0.50.81.3-1.0-0.91.0-1.00.8-0.81.10.2-1.0
Bone: cortical thickness0.30.41.20.4-0.3-0.40.2-0.5-1.10.11.1-0.7
Bone: cortical tissue density1.41.93.51.71.2-1.81.6-1.90.2-1.40.21.1
Condit. Reinf. active minus inactive responses0.20.20.40.50.2-0.50.5-0.7-0.1-0.60.10.2
Condit. Reinf. active-inactive response ratio0.40.51.8-0.0-1.10.2-0.10.3-1.30.40.2-1.1
Condit. Reinf. active responses1.82.23.81.81.2-1.81.8-2.00.3-1.70.31.1
Condit. Reinf. inactive responses3.64.36.82.22.3-2.32.3-2.61.4-2.20.32.1
Incentive salience index mean0.40.51.20.70.6-0.70.8-1.10.4-0.90.10.5
Condit. Reinf. lever presses0.40.61.00.51.0-0.50.7-1.01.0-1.0-0.10.8
Condit. Reinf. active minus inactive responses0.40.41.1-1.0-0.41.0-0.9-0.10.40.7-0.1-0.4
Condit. Reinf. active-inactive response ratio0.00.00.30.10.0-0.20.1-0.5-0.20.0-0.0-0.1
Condit. Reinf. active responses0.81.12.7-1.6-0.41.6-1.40.31.10.9-0.5-0.1
Condit. Reinf. inactive responses1.01.24.5-1.30.31.4-1.00.62.10.3-0.60.7
Condit. Reinf. lever presses3.24.49.5-2.9-1.93.1-2.71.70.42.2-1.2-1.1
Condit. Reinf. lever reinforcers received0.81.12.4-1.6-0.21.6-1.30.21.50.7-0.70.2
Conditioned reinforcement - actives0.70.72.80.51.1-0.30.3-1.20.4-0.21.70.1
Conditioned reinforcement - inactives2.73.18.70.72.1-0.71.1-1.32.9-2.0-1.02.4
Conditioned locomotion3.23.95.82.22.4-2.22.2-2.31.2-2.20.81.7
Patch foraging indifference point 0 sec0.10.10.60.00.50.00.1-0.10.7-0.20.10.1
Patch foraging indifference point AUC0.10.20.50.40.2-0.30.3-0.3-0.6-0.10.7-0.4
Delay disc. indifference point, 0s delay2.32.55.90.71.0-0.91.1-0.71.9-1.7-2.42.4
Delay disc. indifference point, 16s delay0.70.72.30.10.6-0.00.40.31.5-0.9-1.21.1
Delay disc. indifference point, 2s delay0.80.93.2-0.40.30.1-0.10.11.4-0.5-1.81.4
Delay disc. indifference point, 24s delay0.80.82.5-0.8-0.10.8-0.50.81.3-0.2-1.60.7
Delay disc. indifference point, 4s delay1.01.02.30.81.5-0.60.9-0.91.2-1.20.41.0
Delay disc. indifference point, 8s delay0.10.10.5-0.20.30.3-0.10.70.6-0.2-0.30.3
Indifference point function ln k0.10.20.3-0.6-0.50.4-0.6-0.30.20.4-0.1-0.0
Indifference point function log k0.10.20.3-0.6-0.50.4-0.6-0.30.20.4-0.1-0.0
Patch foraging total patch changes 0 sec0.10.10.8-0.10.50.10.0-0.00.9-0.20.00.2
Patch foraging total patch changes 12 sec0.10.20.90.10.30.10.1-0.1-0.10.11.0-0.6
Patch foraging total patch changes 18 sec0.30.31.10.31.0-0.30.40.00.9-0.6-0.20.7
Patch foraging total patch changes 24 sec0.50.61.7-0.50.30.5-0.30.81.3-0.2-1.30.9
Patch foraging total patch changes 6 sec0.00.10.4-0.00.30.1-0.0-0.10.20.10.6-0.3
Patch foraging time to switch 0 sec0.30.41.40.60.2-0.50.40.5-1.0-0.01.2-0.8
Patch foraging water rate 0 sec0.81.34.41.10.9-1.21.1-2.10.5-1.00.70.7
Patch foraging water rate 12 sec0.30.52.1-0.50.80.6-0.5-0.41.40.10.20.6
Patch foraging water rate 18 sec0.30.41.40.50.6-0.30.4-1.20.3-0.31.10.1
Patch foraging water rate 24 sec2.33.26.71.01.8-1.21.2-2.22.6-1.9-0.42.5
Patch foraging water rate 6 sec0.71.04.6-0.40.70.4-0.2-0.72.1-0.5-0.71.4
Seeking ratio, delayed vs. immediate footshock0.80.93.2-0.40.70.3-0.20.11.8-0.7-1.21.4
Distance traveled before self-admin0.10.10.60.00.30.1-0.1-0.0-0.10.30.7-0.2
Distance traveled after self-admin1.11.32.9-1.6-0.21.7-1.51.21.10.9-0.4-0.0
Extensor digitorum longus weight0.41.75.9-0.4-2.20.1-0.60.9-2.40.9-0.8-1.2
Bone: elastic displacement0.30.41.1-0.3-0.20.3-0.50.4-0.70.71.1-0.8
Bone: elastic work1.11.52.7-1.6-1.11.7-1.61.4-0.31.3-0.3-0.8
Bone: endosteal estimation0.61.22.6-1.6-0.91.6-1.50.80.51.1-0.9-0.3
Bone: endosteal perimeter0.30.71.5-1.2-0.41.1-1.10.51.00.5-0.90.2
Epididymis fat weight0.00.10.2-0.40.30.3-0.3-0.10.5-0.0-0.40.4
Delta time in closed arm before/after self-admin2.42.33.8-1.8-2.01.8-1.71.7-0.41.4-1.5-0.6
Delta time in open arm before/after self-admin0.40.41.30.60.9-0.50.5-0.8-0.2-0.11.1-0.4
Diff in mean of infusions in LGA sessions1.21.42.71.30.8-1.51.4-0.41.0-1.6-0.31.3
Delay discount exponential model param0.30.41.20.0-0.5-0.1-0.2-0.4-1.10.70.8-0.8
Extinction: sum of active levers before priming3.33.25.9-2.1-2.02.1-2.02.4-0.61.7-1.5-1.0
Active lever presses in extinction session 64.94.76.7-2.3-2.32.4-2.42.1-1.82.60.2-2.4
Bone: final force0.81.32.7-1.4-1.11.5-1.21.30.30.8-1.6-0.1
Bone: final moment1.11.83.0-1.7-1.31.7-1.51.40.21.1-1.7-0.3
Food consumed during 24 hour testing period0.50.62.9-0.20.70.30.0-0.31.7-0.5-0.21.1
Glucose0.30.51.3-0.2-0.20.3-0.40.5-1.20.80.8-0.9
Heart weight0.40.62.30.10.3-0.20.2-0.51.1-0.7-1.51.1
Delay discount hyperbolic model param0.40.41.3-0.1-0.50.1-0.3-0.2-1.10.80.8-1.0
Intermittent access intake day 1-15 change1.31.32.5-1.6-1.21.4-1.41.20.21.0-1.1-0.1
Intermittent access intake escalation1.11.12.1-1.4-1.01.2-1.31.00.50.7-1.40.2
Intermittent access intake escalation 21.11.11.9-1.3-1.11.4-1.31.3-0.01.0-0.4-0.5
Intermitt. access day 1 inactive lever presses1.41.52.8-1.4-1.21.5-1.11.60.70.6-1.7-0.2
Intermitt. access day 15 inactive lever presses0.60.72.00.10.3-0.20.5-0.31.4-1.0-1.21.2
Intermitt. access escalation Index0.90.81.40.71.0-0.80.7-0.60.9-0.9-0.91.2
Intermittent access day 1 total infusions4.95.69.32.43.0-2.42.4-2.62.0-2.61.02.4
Intermittent access day 15 total infusions2.73.05.91.12.1-1.21.3-1.62.4-1.9-0.32.4
Intermittent access terminal intake (last 3 days)3.33.66.21.52.5-1.51.6-1.92.4-2.10.32.3
Intermittent access total infusions3.74.17.51.72.7-1.71.8-2.12.4-2.20.62.3
Intermittent access day 1 locomotion5.05.38.72.12.9-2.12.3-2.22.4-2.70.32.6
Intermittent access day 15 total locomotion2.83.06.21.12.1-1.21.3-1.72.5-2.0-0.12.4
Intermittent access total locomotion3.54.06.82.02.6-1.92.0-2.01.9-2.30.92.0
Intermittent access standard deviation1.61.73.4-1.5-0.21.5-1.21.31.90.3-1.70.8
Left kidney weight3.18.613.1-3.6-3.53.4-3.62.8-1.63.4-1.2-2.2
Right kidney weight4.111.619.3-4.4-3.74.3-4.33.1-1.33.9-1.4-2.4
Cocaine induced anxiety0.60.71.5-0.8-1.20.8-0.70.7-0.40.7-1.1-0.5
Post-drug Anxiety0.20.20.50.1-0.70.00.10.4-0.70.0-0.4-0.6
Baseline Anxiety1.21.32.01.41.4-1.31.4-0.90.4-1.30.90.7
Tail length2.98.716.3-4.0-2.64.0-3.93.0-0.33.3-0.7-2.0
Length with tail4.014.729.0-5.4-3.45.2-5.13.90.44.0-2.2-1.7
Length without tail2.45.310.9-3.3-2.03.1-3.12.00.72.1-2.3-0.3
Times rat made contact with spout0.60.72.3-0.2-0.90.5-0.50.3-1.50.90.7-1.0
Lifetime Intake2.42.74.71.52.2-1.41.5-2.01.6-1.70.91.7
Liver weight, left0.40.62.60.0-0.70.1-0.20.3-1.60.70.1-1.2
Liver weight, right0.40.62.10.10.30.2-0.1-0.8-0.90.71.5-1.1
Locomotor activity1.01.64.8-0.0-0.50.3-0.4-0.3-1.91.22.2-1.9
Locomotor testing distance0.50.93.60.1-0.00.0-0.2-0.4-1.30.91.9-1.3
Locomotor testing rearing0.81.34.01.20.9-1.10.9-1.6-0.7-0.32.0-0.2
Locomotion in novel chamber0.20.20.40.4-0.4-0.40.4-0.1-0.7-0.10.6-0.6
Locomotion in novel chamber post-restriction0.00.00.10.1-0.3-0.00.20.3-0.2-0.0-0.1-0.2
Fecal boli incidents, locomotor time 11.21.32.51.40.7-1.41.3-1.1-0.8-0.91.6-0.3
Change in fecal boli incidents, locomotor task1.31.22.4-0.8-1.40.9-0.91.1-1.31.10.2-1.5
Time >=10cm from walls, locomotor time 10.10.10.40.0-0.30.10.00.3-0.3-0.0-0.6-0.2
Bouts of movement, locomotor time 10.91.03.40.21.1-0.20.4-0.61.9-0.9-0.81.6
Total resting periods, locomotor time 10.70.72.50.21.0-0.20.3-0.51.6-0.8-0.51.3
Rest time, locomotor task time 10.50.51.11.10.1-1.01.0-0.6-0.6-0.80.4-0.1
Distance moved, locomotor task time 10.10.10.3-0.3-0.10.1-0.30.30.30.1-0.50.4
Vertical activity count, locomotor time 10.70.71.4-1.2-0.21.2-1.00.81.00.7-0.50.2
Time >=10cm from walls, locomotor time 21.31.42.31.51.2-1.51.5-1.3-0.0-1.31.00.5
Bouts of movement, locomotor time 20.20.20.60.20.80.10.1-0.40.5-0.10.60.4
Total resting periods, locomotor time 20.30.31.30.30.9-0.00.2-0.50.4-0.11.10.1
Rest time, locomotor task time 20.40.41.30.80.5-0.60.7-0.6-0.3-0.51.2-0.3
Distance moved, locomotor task time 20.20.30.80.30.5-0.40.3-0.40.6-0.5-0.40.9
Vertical activity count, locomotor time 20.30.41.1-0.60.10.6-0.50.21.00.1-0.80.8
Light reinforcement 10.50.92.30.71.5-0.60.7-1.11.0-0.80.70.8
Light reinforcement 21.41.84.31.80.8-1.71.7-2.1-0.3-1.20.80.5
Bone: marrow area0.61.32.8-1.7-0.91.7-1.50.90.51.2-0.8-0.4
Bone: maximum diameter0.71.32.4-1.5-1.21.5-1.41.20.11.0-1.1-0.5
Bone: maximum force1.22.13.8-1.9-1.31.9-1.61.40.51.1-2.0-0.0
Bone: maximum moment1.52.54.4-2.1-1.42.1-1.91.50.41.3-2.0-0.2
Mean time between licks in bursts0.20.30.60.40.5-0.50.5-0.80.8-0.7-0.20.6
Mean num. licks in bursts3.44.06.5-2.0-2.52.1-2.21.6-1.92.4-0.5-2.1
Cd content in liver0.30.31.2-0.5-0.20.6-0.61.1-0.50.60.2-0.5
Co content in liver0.10.10.30.5-0.3-0.60.50.1-0.4-0.3-0.1-0.1
Cu content in liver0.30.41.5-0.7-0.50.6-0.60.70.30.3-1.20.1
Fe content in liver0.10.10.10.30.2-0.30.30.30.2-0.4-0.20.2
K content in liver0.10.10.20.20.4-0.20.2-0.40.4-0.30.4-0.1
Mg content in liver0.30.30.70.70.2-0.70.7-0.9-0.4-0.40.7-0.4
Mn content in liver0.70.83.50.60.2-0.40.4-0.4-1.10.11.9-1.2
Na content in liver0.40.41.9-0.70.60.6-0.50.01.4-0.0-0.30.6
Rb content in liver0.91.13.50.70.1-1.01.0-0.20.9-1.3-1.91.2
Se content in liver2.73.36.32.51.0-2.42.3-2.2-1.3-1.41.7-0.1
Sr content in liver0.50.52.30.60.3-0.40.4-0.4-0.70.01.5-0.6
Zn content in liver0.10.10.40.3-0.2-0.40.4-0.1-0.0-0.4-0.60.2
Bone: minimum diameter0.71.43.0-1.6-0.21.5-1.30.81.70.5-1.40.6
Time in familiar zone, hab. session 12.62.45.9-1.4-2.41.3-1.50.9-1.81.8-0.6-1.4
Time in novel zone, hab. session 13.53.46.51.92.6-1.82.0-1.31.7-2.11.31.5
Total zone transitions, hab. session 10.40.61.30.50.9-0.50.5-1.10.9-0.7-0.11.0
Total locomotion distance, hab. session 10.30.41.2-0.50.80.8-0.4-0.01.10.20.9-0.0
Locomotion velocity, hab. session 10.30.41.4-0.50.50.8-0.50.10.60.41.2-0.4
Time in familiar zone, hab. session 22.32.34.5-1.6-2.11.5-1.52.1-0.81.5-0.4-1.6
Time in novel zone, hab. session 21.01.02.41.11.5-1.00.9-1.60.2-0.80.80.7
Total zone transitions, hab. session 23.14.08.72.32.1-2.12.1-2.90.5-1.92.11.1
Total locomotion distance, hab. session 21.11.52.71.11.6-0.81.1-1.31.4-1.31.21.0
Locomotion velocity, hab. session 20.91.22.11.01.4-0.81.1-1.21.1-1.21.30.8
Novel to familiar place preference ratio0.20.20.8-0.10.20.00.00.30.6-0.2-0.90.5
Novelty place preference0.20.20.60.00.5-0.10.10.20.7-0.3-0.80.6
Time in novel zone, NPP test0.30.30.60.30.6-0.30.3-0.00.8-0.5-0.80.7
Total zone transitions, NPP test0.20.31.50.20.4-0.20.1-1.2-0.0-0.10.60.2
Total locomotion distance, NPP test1.01.33.2-1.6-0.51.8-1.60.70.31.30.4-0.8
Locomotion velocity, NPP test1.11.53.6-1.7-0.61.9-1.70.80.21.40.7-1.0
Intraocular pressure0.30.40.70.40.2-0.60.60.40.7-0.8-0.60.8
Delta distance traveled before/after self-admin1.92.03.6-1.9-0.91.8-1.61.71.00.9-1.80.0
Delta ambulatory time before/after self-admin1.92.14.0-2.0-0.81.9-1.71.61.20.9-1.70.1
Parametrial fat weight2.85.413.0-1.3-2.71.6-1.71.3-3.62.71.0-3.3
Pavlov. Cond. lever latency1.01.33.2-0.9-1.60.6-0.81.8-0.80.8-1.7-0.3
Pavlov. Cond. magazine entry latency1.82.312.40.81.7-0.40.5-2.00.3-0.23.5-0.3
Pavlov. Cond. change in total contacts2.93.16.41.42.5-1.11.4-2.51.8-1.41.91.3
Pavlov. Cond. index score2.02.510.21.12.0-0.70.9-2.30.6-0.63.2-0.0
Pavlov. Cond. latency score1.62.06.91.01.9-0.70.9-2.10.8-0.72.60.2
Pavlov. Cond. lever contacts0.70.82.40.51.3-0.30.5-1.40.9-0.51.50.1
Pavlov. Cond. magazine entry number2.02.511.3-1.1-2.00.6-0.82.3-0.50.5-3.40.0
Pavlov. Cond. intertrial magazine entries0.30.40.90.80.1-0.90.7-1.0-0.4-0.5-0.50.4
Pavlov. Cond. lever-magazine prob. diff.2.42.911.11.32.2-0.81.1-2.50.7-0.83.30.1
Pavlov. Cond. response bias1.41.79.80.51.2-0.10.2-1.70.10.13.1-0.6
Pavlov. Cond. lever latency1.62.24.92.11.0-2.21.9-1.0-1.0-1.31.40.0
Pavlov. Cond. magazine entry latency0.70.82.2-1.3-0.41.5-1.20.70.80.8-0.5-0.3
Pavlov. Cond. change in total contacts2.63.66.5-2.5-1.02.5-2.21.81.81.2-2.40.5
Pavlov. Cond. index score1.52.04.9-2.0-0.72.2-1.81.01.11.2-1.1-0.1
Pavlov. Cond. latency score1.31.74.2-1.9-0.62.0-1.60.91.21.0-1.00.0
Pavlov. Cond. lever contacts1.52.04.6-2.0-0.82.1-1.71.01.21.1-1.50.2
Pavlov. Cond. magazine entry number1.41.84.31.90.9-2.11.8-0.9-0.7-1.30.90.2
Pavlov. Cond. intertrial magazine entries0.20.30.90.80.1-1.00.80.1-0.5-0.50.10.1
Pavlov. Cond. lever-magazine prob. diff.1.72.15.2-2.1-0.92.3-1.91.10.91.4-1.0-0.3
Pavlov. Cond. response bias1.62.24.7-2.0-0.72.2-1.80.91.51.0-1.70.4
Time in closed arm before self-admin2.63.05.02.12.2-2.02.0-1.60.9-1.90.61.4
Time in closed arm after self-admin0.30.31.30.20.0-0.20.40.30.4-0.6-1.10.7
Time in open arm before self-admin3.63.96.9-2.5-1.92.6-2.52.0-0.52.2-0.0-1.7
Time in open arm after self-admin1.11.22.0-1.3-0.31.4-1.40.5-0.01.41.0-1.2
Bone: periosteal estimation0.92.03.9-2.0-1.42.0-1.81.10.11.5-0.9-0.7
Bone: periosteal perimeter0.71.12.1-1.4-1.01.4-1.40.9-0.11.2-0.1-0.9
Bone: post-yield work0.81.24.2-0.70.10.6-0.40.41.8-0.3-2.01.3
Progressive ratio test 1 active lever presses1.41.44.80.31.6-0.40.5-0.82.2-1.1-0.61.8
Progressive ratio test 1 breakpoint0.80.93.5-0.01.10.00.1-0.41.9-0.7-0.61.4
Progressive ratio test 1 inactive lever presses2.02.16.00.61.5-0.60.9-1.32.5-1.6-0.92.1
Progressive ratio test 2 active lever presses1.51.63.20.71.8-0.70.8-1.41.8-1.20.51.6
Progressive ratio test 2 breakpoint1.31.53.10.71.8-0.70.7-1.41.6-1.10.71.4
Progressive ratio test 2 inactive lever presses3.94.510.91.02.0-1.21.5-1.53.3-2.5-1.63.1
Incentive Sensitization - Responses0.60.61.50.50.9-0.60.5-1.20.7-0.70.70.9
Incentive Sensitization - Breakpoint0.40.41.20.40.7-0.50.4-1.10.6-0.60.60.8
Sum of active levers in priming session hrs 5-60.10.10.3-0.4-0.50.2-0.40.4-0.10.2-0.5-0.1
Progressive ratio0.20.20.90.20.9-0.10.2-0.50.5-0.20.8-0.0
Food seeking constrained by brief footshock0.91.12.6-1.5-0.31.6-1.40.90.81.0-0.3-0.5
Seeking ratio, punishment vs. effort0.20.30.9-0.5-0.30.5-0.40.20.70.1-1.00.4
Retroperitoneal fat weight0.41.36.10.8-0.3-0.70.4-0.3-2.50.51.4-1.4
Reaction time number correct0.10.10.3-0.2-0.50.2-0.2-0.2-0.30.30.0-0.1
Reaction time mean minus median0.50.62.1-0.9-0.50.8-0.91.4-0.10.7-0.5-0.5
Reaction time mean minus median AUC1.11.42.9-1.5-1.11.4-1.41.7-0.31.1-0.6-0.8
Reaction time num false alarms0.40.51.11.00.6-1.00.9-0.40.1-0.80.40.5
Reaction time num false alarms AUC0.40.61.21.10.7-1.11.0-0.4-0.0-0.90.60.3
Reaction time trials correct on left0.10.10.3-0.2-0.50.2-0.2-0.2-0.30.30.0-0.1
Reaction time trials on left0.10.10.3-0.2-0.60.3-0.3-0.2-0.40.40.0-0.2
Reaction time mean0.10.20.3-0.60.00.5-0.60.50.20.3-0.3-0.0
Reaction time mean AUC0.10.10.3-0.50.10.4-0.50.40.10.30.0-0.2
Median of all reaction times0.00.00.1-0.20.40.2-0.30.00.30.0-0.00.2
Reaction time omissions0.20.30.8-0.3-0.60.2-0.40.5-0.70.60.2-0.9
Reaction time false alarm rate0.40.61.11.00.9-1.11.0-0.20.2-0.90.40.5
Reaction time premature initiation rate0.91.23.10.61.7-0.60.8-0.81.6-1.10.71.0
Reaction time premature initiations0.60.92.00.51.4-0.50.7-0.91.4-0.90.70.9
Std. dev. reaction times0.40.61.6-1.0-0.30.8-0.91.30.40.4-0.90.0
Reaction time trials completed0.10.10.3-0.2-0.60.3-0.3-0.2-0.40.40.0-0.2
Reaction time trials AUC0.20.30.7-0.3-0.90.3-0.4-0.1-0.80.60.1-0.5
Run reversals in cocaine runway, females0.40.41.4-0.6-0.30.4-0.50.40.70.0-1.20.6
Run reversals in cocaine runway, males3.13.07.4-0.9-1.91.2-1.21.0-2.51.91.2-2.7
Latency to leave start box in cocaine runway0.50.61.9-0.00.3-0.30.2-0.21.0-0.6-1.41.3
Latency to leave start box in cocaine runway, F0.70.72.10.30.4-0.50.5-0.60.9-0.9-1.41.3
Latency to leave start box in cocaine runway, M0.10.10.3-0.3-0.20.0-0.30.6-0.00.30.10.0
Std. dev. time between licks in bursts2.02.46.60.92.0-1.01.2-1.42.6-1.70.31.6
Total sessions with >9 infusions0.90.92.01.01.2-0.90.9-1.40.1-0.61.40.3
Short access day 1 total inactive lever presses3.23.67.51.11.9-1.21.5-1.42.7-2.3-1.42.7
Short access day 10 total inactive lever presses0.70.84.0-0.6-0.30.4-0.20.61.0-0.3-2.00.8
Short access day 1 total infusions0.50.51.90.50.9-0.50.5-1.40.6-0.50.40.7
Short access day 10 total infusions0.50.60.90.80.9-0.80.7-0.90.5-0.70.60.7
Short access total infusions0.70.82.21.01.0-0.90.8-1.50.1-0.61.30.4
Short access day 1 locomotion0.20.30.40.50.6-0.50.5-0.60.3-0.50.30.4
Short access day 10 total locomotion0.91.14.50.21.5-0.10.4-0.32.1-1.00.01.2
Short access total locomotion1.31.32.41.31.6-1.11.2-1.30.7-1.21.10.7
One hour access (0.3 mA shock)1.82.17.80.22.1-0.10.3-1.42.8-1.10.61.8
Compulsive drug intake0.10.10.3-0.20.00.2-0.2-0.50.10.20.1-0.2
One hour access (shock baseline)1.51.83.90.81.9-0.70.9-1.32.0-1.40.71.6
Social response proportion1.01.13.6-1.0-1.30.9-0.71.40.50.2-1.90.2
Social responses0.10.10.3-0.5-0.50.4-0.20.40.4-0.0-0.6-0.2
Social time0.91.34.1-1.3-0.51.1-1.00.61.50.2-2.00.8
Soleus weight0.10.20.70.1-0.5-0.20.1-0.2-0.80.20.4-0.5
Bone: stiffness0.91.45.3-1.2-1.31.3-1.01.00.40.6-2.30.2
Tibialis anterior weight0.72.56.8-1.0-2.20.8-1.21.4-2.61.6-0.3-1.7
Time to tail flick, vehicle, before self-admin0.80.81.71.10.9-1.11.0-1.30.2-0.80.30.6
Time to tail flick, vehicle, after self-admin0.10.20.70.20.6-0.00.20.10.0-0.00.9-0.4
Time to tail flick, test, before self-admin2.82.75.51.11.9-1.11.3-1.52.1-1.7-1.12.4
Time to tail flick, test, after self-admin0.10.10.30.20.5-0.10.2-0.20.5-0.3-0.20.4
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.60.20.8-0.51.00.40.40.4-0.5
Delta time to tail flick, test, before/after SA1.61.43.8-0.4-0.90.5-0.60.5-1.81.21.6-2.0
Tibia length1.64.67.9-2.8-2.12.8-2.61.90.21.9-2.6-0.2
Ambulatory time before self-admin0.10.10.80.20.4-0.10.1-0.10.0-0.00.9-0.1
Ambulatory time after self-admin2.22.44.6-2.1-0.62.1-1.81.81.60.9-1.50.4
Bone: tissue strength1.71.66.4-1.2-0.31.1-0.81.31.40.1-2.51.0
Total heroin consumption0.30.31.00.00.5-0.20.20.01.0-0.6-0.70.9
Bone: trabecular number0.71.22.6-1.5-1.21.6-1.40.40.31.0-1.1-0.1
Bone: trabecular spacing0.40.61.4-0.50.00.5-0.61.1-0.40.71.0-1.2
Bone: trabecular thickness0.10.10.3-0.2-0.50.1-0.2-0.6-0.40.2-0.50.2
Bone: trabecular tissue density1.52.18.40.4-0.7-0.3-0.10.1-2.91.02.0-2.0
Water consumed over 24 hours0.20.30.7-0.7-0.70.8-0.70.10.10.5-0.2-0.0
Number of responses in last shaping day2.12.24.11.12.0-1.21.2-1.61.9-1.5-0.01.8