Hub : Genes

Tub

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tub 0.06 0.04 1.1e-04 0.01 0.02 0.02 0.02 4.0e-02 1.1e-03 1.4e-03 3.2e-03
2 IC gene expression Tub 0.22 0.13 7.3e-05 0.07 0.08 0.05 0.07 6.0e-04 4.3e-04 3.3e-03 8.2e-04
3 BLA intron excision ratio chr1_172456153_172457065 0.12 0.08 2.6e-05 0.07 0.07 0.06 0.06 2.3e-04 2.1e-04 6.8e-04 4.9e-04
4 BLA intron excision ratio chr1_172454902_172457065 0.25 0.14 5.0e-12 0.2 0.21 0.2 0.2 1.1e-10 1.5e-11 5.6e-11 4.6e-11
5 NAcc intron excision ratio chr1_172454902_172457065 0.09 0.06 8.8e-15 0.11 0.1 0.1 0.11 3.0e-16 2.8e-15 1.2e-15 5.8e-16
6 NAcc intron excision ratio chr1_172456153_172457065 0.02 0.02 6.3e-04 0.02 0.02 0.02 0.02 4.3e-04 6.9e-04 1.2e-03 9.3e-04
7 Brain intron excision ratio chr1_172454902_172457065 0.22 0.13 0.0e+00 0.21 0.21 0.21 0.22 1.1e-19 2.2e-19 6.4e-19 8.5e-20
8 Brain intron excision ratio chr1_172456153_172457065 0.05 0.04 5.9e-05 0.04 0.04 0.04 0.04 1.5e-04 1.6e-04 2.1e-04 1.1e-04
9 Brain mRNA stability Tub 0.21 0.12 0.0e+00 0.24 0.23 0.23 0.24 4.7e-22 1.5e-21 1.5e-21 5.4e-22
10 IC intron excision ratio chr1_172454902_172455986 0.1 0.08 3.3e-04 0.06 0.06 0.05 0.06 1.1e-03 2.3e-03 4.8e-03 1.5e-03
11 PL intron excision ratio chr1_172454902_172455986 0.05 0.04 7.3e-06 0.05 0.05 0.05 0.06 1.4e-06 4.7e-06 3.6e-06 1.2e-06
12 Brain intron excision ratio chr1_172454902_172455986 0.04 0.04 5.9e-04 0.04 0.02 0.01 0.03 2.1e-04 4.0e-03 3.0e-02 1.3e-03
13 PL intron excision ratio chr1_172456153_172457065 0.04 0.03 4.6e-05 0.03 0.04 0.03 0.03 3.0e-04 1.3e-05 3.0e-04 4.2e-04
14 IL intron excision ratio chr1_172454902_172457065 0.14 0.1 4.6e-03 0.09 0.04 0.04 0.05 3.7e-03 3.7e-02 4.7e-02 2.3e-02
15 IC intron excision ratio chr1_172454902_172457065 0.34 0.17 9.4e-14 0.3 0.32 0.31 0.31 4.0e-13 3.8e-14 1.3e-13 1.1e-13
16 Adipose gene expression Tub 0.04 0.03 2.2e-05 0.02 0.02 0.02 0.02 3.1e-03 1.1e-03 3.3e-03 1.9e-03
17 PL intron excision ratio chr1_172454902_172457065 0.26 0.13 0.0e+00 0.27 0.27 0.26 0.27 1.5e-29 8.0e-30 6.9e-28 7.9e-30
18 IC intron excision ratio chr1_172456153_172457065 0.12 0.08 3.2e-05 0.1 0.11 0.08 0.11 6.4e-05 2.3e-05 2.4e-04 2.7e-05
19 OFC isoform ratio XM_063282067.1 0.2 0.14 8.9e-03 0.03 0.03 0 0.02 5.7e-02 6.4e-02 2.8e-01 9.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.2-0.5-0.4-0.50.50.4-0.40.3-0.4-0.4-0.3-0.5-0.5-0.40.50.30.30.4-0.2-0.0
Area under the delay curve0.80.91.3-0.8-0.6-1.11.11.1-1.11.0-1.1-1.0-0.9-0.8-0.8-1.10.81.01.00.8-0.90.8
BMI with tail4.314.827.25.25.05.0-4.8-4.24.2-4.24.13.73.93.53.53.6-3.6-3.2-3.1-2.92.2-0.3
BMI without tail5.917.926.95.24.85.2-5.0-4.64.6-4.64.44.44.54.24.24.0-4.2-3.7-3.5-3.52.6-0.7
Body weight2.711.916.73.83.44.1-4.0-3.93.9-3.83.73.43.73.43.43.4-3.4-3.3-3.1-3.02.5-1.2
Weight adjusted by age1.21.93.11.81.71.7-1.6-1.51.5-1.51.41.41.31.41.41.2-1.4-1.2-1.1-1.30.8-0.1
Bone surface0.10.20.3-0.5-0.5-0.60.50.5-0.50.4-0.5-0.4-0.4-0.4-0.4-0.50.40.40.40.4-0.30.1
Bone volume0.00.00.10.00.1-0.10.10.2-0.20.0-0.2-0.1-0.1-0.2-0.2-0.20.20.20.20.2-0.30.2
Breakpoint value in progressive ratio session0.20.31.20.70.90.10.10.4-0.40.2-0.3-0.3-0.2-0.4-0.4-0.50.40.60.70.5-0.91.1
Number of licking bursts0.40.60.8-0.5-0.4-0.80.80.9-0.90.7-0.9-0.8-0.8-0.7-0.7-0.90.80.80.80.8-0.80.6
Context. condit. distance diff. score0.30.31.71.01.20.3-0.10.2-0.20.3-0.2-0.0-0.5-0.2-0.2-0.40.10.60.60.4-0.91.3
Locomotion velocity, session 10.60.61.50.00.2-0.30.40.6-0.60.5-0.5-0.9-0.8-1.2-1.2-0.61.20.70.71.2-0.80.8
Locomotion distance, session 10.20.30.80.70.90.3-0.10.1-0.10.2-0.1-0.3-0.2-0.7-0.7-0.20.60.40.40.7-0.60.8
Locomotion velocity, session 20.20.20.60.60.70.2-0.10.2-0.20.2-0.1-0.2-0.3-0.5-0.5-0.30.50.40.40.5-0.60.8
Locomotion distance, session 20.71.05.72.22.41.4-1.2-0.60.6-0.60.70.60.60.40.40.3-0.5-0.00.0-0.1-0.51.4
Locomotion velocity, session 30.30.30.60.70.70.7-0.7-0.70.7-0.70.60.40.50.40.40.6-0.4-0.5-0.5-0.30.4-0.1
Locomotion distance, session 30.30.30.50.60.60.6-0.6-0.70.7-0.50.60.70.50.70.70.5-0.7-0.5-0.5-0.60.4-0.1
Stereotopy head waving bouts, day 30.20.30.6-0.6-0.5-0.50.50.5-0.50.4-0.4-0.4-0.4-0.8-0.8-0.40.80.40.30.7-0.20.0
Stereotopy head waving duration, day 30.10.10.20.40.50.2-0.2-0.10.1-0.10.1-0.0-0.1-0.4-0.4-0.00.40.10.10.4-0.20.4
Locomotion velocity, session 72.22.46.10.40.8-0.81.11.6-1.61.6-1.6-1.4-1.5-1.2-1.2-1.81.22.02.01.5-2.22.5
Locomotion distance, session 70.81.01.7-0.20.0-0.80.91.0-1.01.1-1.1-0.9-1.2-0.9-0.9-1.20.91.21.21.0-1.31.3
Stereotopy head waving bouts, day 70.00.00.10.10.10.1-0.10.0-0.0-0.00.10.20.1-0.2-0.20.00.1-0.0-0.00.20.0-0.0
Stereotopy head waving duration, day 70.80.91.41.00.91.1-1.1-1.01.0-1.11.11.21.00.80.81.0-0.9-0.9-0.9-0.70.8-0.5
Locomotion velocity, session 82.12.54.3-0.10.3-1.11.31.6-1.61.6-1.6-1.5-1.7-1.7-1.7-1.81.61.91.91.8-2.02.1
Locomotion distance, session 80.50.84.81.92.21.0-0.8-0.20.2-0.10.20.40.10.30.3-0.1-0.40.40.40.1-0.91.7
Degree of sensitization distance0.50.51.70.50.7-0.20.30.7-0.70.6-0.6-0.5-0.6-0.5-0.5-0.80.60.90.90.7-1.11.3
Degree of sensitization stereotypy0.10.10.30.50.50.4-0.4-0.20.2-0.30.30.50.30.20.20.2-0.3-0.2-0.2-0.10.10.1
Conditioned locomotion0.20.21.4-1.0-1.2-0.50.30.0-0.00.20.0-0.2-0.2-0.3-0.30.10.3-0.3-0.30.00.6-1.0
Cocaine response after cond. corrected0.91.12.0-0.2-0.0-0.70.80.9-0.91.0-1.0-1.1-1.0-1.4-1.4-1.01.41.11.11.3-1.11.1
Cocaine response after cond. not corrected0.10.10.70.70.80.3-0.2-0.00.0-0.10.0-0.00.1-0.3-0.3-0.10.30.20.20.3-0.40.8
Cocaine response before conditioning1.21.52.21.41.31.4-1.4-1.11.1-1.51.21.31.31.41.41.1-1.5-1.0-0.9-1.30.7-0.1
Saline control response2.33.04.90.80.51.5-1.6-1.71.7-1.81.71.81.82.22.21.8-2.1-1.8-1.8-2.11.7-1.5
Bone: connectivity density0.10.10.1-0.2-0.2-0.40.40.4-0.40.3-0.4-0.4-0.2-0.3-0.3-0.40.30.40.40.3-0.30.2
Bone: cortical apparent density0.50.71.4-1.2-1.2-1.01.00.7-0.70.8-0.8-0.9-0.9-0.9-0.9-0.60.90.50.50.7-0.3-0.1
Bone: cortical area0.00.10.30.50.60.2-0.10.0-0.0-0.00.00.0-0.00.00.0-0.1-0.00.20.20.1-0.40.5
Bone: cortical porosity0.00.00.2-0.4-0.4-0.20.20.1-0.10.1-0.10.0-0.00.10.1-0.0-0.0-0.0-0.0-0.20.1-0.3
Bone: cortical porosity0.20.20.9-0.9-1.0-0.60.50.4-0.40.4-0.3-0.2-0.3-0.1-0.1-0.20.20.10.10.00.1-0.5
Bone: cortical thickness0.10.10.80.80.90.5-0.4-0.30.3-0.20.20.10.20.20.20.1-0.20.00.1-0.1-0.20.5
Bone: cortical thickness0.30.31.40.81.00.2-0.00.3-0.30.2-0.3-0.4-0.2-0.4-0.4-0.50.30.60.60.5-0.91.2
Bone: cortical tissue density0.40.61.3-1.1-1.1-0.90.90.6-0.60.7-0.7-0.8-0.9-0.8-0.8-0.50.80.40.40.7-0.2-0.2
Condit. Reinf. active minus inactive responses1.21.32.9-0.2-0.50.6-0.8-1.01.0-1.11.01.21.21.21.21.2-1.1-1.3-1.4-1.31.5-1.7
Condit. Reinf. active-inactive response ratio1.01.03.2-0.5-0.80.4-0.6-0.90.9-0.90.91.00.80.90.91.1-0.9-1.2-1.3-1.11.5-1.8
Condit. Reinf. active responses1.21.53.7-0.4-0.80.6-0.8-1.11.1-1.21.11.21.31.21.21.3-1.1-1.5-1.5-1.31.7-1.9
Condit. Reinf. inactive responses0.50.60.90.20.10.6-0.7-0.80.8-0.90.80.71.00.80.80.8-0.7-0.9-0.8-0.80.9-0.8
Incentive salience index mean0.60.73.0-0.8-1.10.1-0.3-0.60.6-0.60.60.70.70.70.70.9-0.6-1.0-1.1-0.81.3-1.7
Condit. Reinf. lever presses0.20.31.8-1.1-1.3-0.50.3-0.00.00.1-0.0-0.1-0.0-0.2-0.20.20.2-0.4-0.4-0.00.7-1.3
Condit. Reinf. active minus inactive responses0.30.40.60.40.30.6-0.7-0.70.7-0.70.60.70.80.80.80.7-0.8-0.7-0.7-0.80.6-0.4
Condit. Reinf. active-inactive response ratio0.10.10.3-0.0-0.10.2-0.2-0.30.3-0.20.20.40.40.50.50.3-0.5-0.3-0.3-0.50.4-0.3
Condit. Reinf. active responses0.40.60.90.80.70.9-0.8-0.80.8-0.80.70.80.90.90.90.7-1.0-0.7-0.6-0.80.5-0.2
Condit. Reinf. inactive responses0.71.02.21.51.41.3-1.2-1.01.0-1.11.00.91.00.90.90.9-1.0-0.7-0.7-0.70.40.1
Condit. Reinf. lever presses1.92.64.42.12.02.0-2.0-1.71.7-1.61.71.61.61.71.71.5-1.8-1.4-1.3-1.41.0-0.2
Condit. Reinf. lever reinforcers received0.30.40.80.60.50.7-0.7-0.70.7-0.70.60.70.70.80.80.6-0.9-0.6-0.6-0.70.5-0.2
Conditioned reinforcement - actives0.40.61.11.01.00.9-0.9-0.70.7-0.80.70.80.91.01.00.6-0.9-0.6-0.5-0.80.3-0.0
Conditioned reinforcement - inactives0.20.30.5-0.2-0.1-0.50.50.6-0.60.5-0.6-0.6-0.6-0.7-0.7-0.60.70.60.60.7-0.60.4
Conditioned locomotion0.91.22.00.1-0.20.7-0.8-1.11.1-1.11.11.21.21.11.11.2-1.2-1.3-1.3-1.31.4-1.4
Patch foraging indifference point 0 sec1.73.15.11.51.31.8-1.8-1.61.6-2.01.72.32.02.12.11.7-2.0-1.6-1.6-2.11.4-0.9
Patch foraging indifference point AUC0.10.10.30.00.1-0.20.20.2-0.20.4-0.3-0.3-0.4-0.6-0.6-0.30.50.40.30.5-0.40.4
Delay disc. indifference point, 0s delay0.00.00.20.50.50.3-0.3-0.20.2-0.10.20.00.20.10.10.10.0-0.0-0.00.0-0.10.1
Delay disc. indifference point, 16s delay1.61.82.3-0.7-0.4-1.31.31.5-1.51.4-1.5-1.3-1.3-1.2-1.2-1.51.31.51.51.3-1.51.5
Delay disc. indifference point, 2s delay0.20.31.3-1.1-1.1-0.80.70.4-0.40.5-0.5-0.3-0.3-0.2-0.2-0.30.20.20.20.20.0-0.3
Delay disc. indifference point, 24s delay0.10.10.5-0.1-0.1-0.00.00.1-0.1-0.0-0.10.30.10.60.6-0.0-0.60.00.0-0.7-0.00.3
Delay disc. indifference point, 4s delay1.21.32.3-1.5-1.5-1.41.31.1-1.11.0-1.1-1.2-1.0-1.3-1.3-1.01.20.80.81.3-0.50.2
Delay disc. indifference point, 8s delay0.30.40.8-0.10.0-0.50.50.7-0.70.7-0.7-0.7-0.6-0.4-0.4-0.70.50.80.80.5-0.80.9
Indifference point function ln k0.40.81.10.90.81.0-1.0-0.90.9-0.80.91.00.91.11.10.9-1.0-0.8-0.8-0.90.7-0.4
Indifference point function log k0.40.81.10.90.81.0-1.0-0.90.9-0.80.91.00.91.11.10.9-1.0-0.8-0.8-0.90.7-0.4
Patch foraging total patch changes 0 sec2.24.16.71.71.42.1-2.1-1.91.9-2.32.02.62.32.32.32.0-2.2-1.9-1.9-2.31.7-1.1
Patch foraging total patch changes 12 sec0.20.30.60.60.50.6-0.6-0.40.4-0.60.60.70.50.60.60.6-0.6-0.5-0.5-0.70.4-0.4
Patch foraging total patch changes 18 sec1.21.92.91.10.81.4-1.5-1.41.4-1.51.51.71.51.31.31.5-1.3-1.4-1.4-1.41.3-1.0
Patch foraging total patch changes 24 sec0.20.30.60.20.10.5-0.5-0.50.5-0.80.60.80.60.50.50.6-0.5-0.6-0.6-0.60.6-0.6
Patch foraging total patch changes 6 sec0.40.51.51.21.21.0-0.9-0.50.5-0.80.61.10.80.70.70.5-0.7-0.3-0.3-0.70.10.3
Patch foraging time to switch 0 sec0.81.52.2-1.5-1.4-1.51.41.2-1.21.2-1.1-1.4-1.3-1.4-1.4-1.21.41.01.01.3-0.80.1
Patch foraging water rate 0 sec0.20.40.70.60.50.7-0.7-0.60.6-0.60.60.80.70.70.70.6-0.7-0.6-0.6-0.70.5-0.3
Patch foraging water rate 12 sec1.32.86.92.62.62.2-2.1-1.71.7-1.61.61.71.61.61.61.4-1.6-1.2-1.0-1.20.60.4
Patch foraging water rate 18 sec0.30.51.81.31.40.9-0.8-0.60.6-0.50.50.70.60.80.80.3-0.7-0.2-0.1-0.4-0.10.6
Patch foraging water rate 24 sec0.30.42.01.31.40.9-0.7-0.40.4-0.50.40.50.60.60.60.2-0.6-0.1-0.1-0.3-0.20.7
Patch foraging water rate 6 sec0.10.10.20.1-0.00.2-0.2-0.20.2-0.20.30.30.30.40.40.3-0.4-0.2-0.3-0.30.3-0.4
Seeking ratio, delayed vs. immediate footshock1.01.22.3-1.5-1.4-1.41.41.1-1.11.1-1.2-0.9-1.1-1.1-1.1-1.01.00.90.91.0-0.60.2
Distance traveled before self-admin0.10.20.7-0.8-0.8-0.60.60.4-0.40.5-0.3-0.4-0.3-0.2-0.2-0.30.20.20.20.2-0.0-0.3
Distance traveled after self-admin0.70.81.20.40.10.8-0.9-0.90.9-0.91.10.91.00.90.91.0-0.9-1.1-1.0-1.01.0-1.1
Extensor digitorum longus weight0.10.42.41.41.50.8-0.6-0.30.3-0.10.20.00.20.00.00.0-0.10.20.20.2-0.50.9
Bone: elastic displacement0.00.10.20.10.2-0.10.10.2-0.20.0-0.2-0.00.10.30.3-0.2-0.20.20.3-0.2-0.30.5
Bone: elastic work0.10.10.30.50.50.2-0.10.1-0.1-0.1-0.00.10.20.30.3-0.1-0.30.20.2-0.2-0.30.5
Bone: endosteal estimation0.20.50.8-0.4-0.3-0.60.70.8-0.80.7-0.7-0.5-0.6-0.8-0.8-0.70.90.70.70.8-0.70.5
Bone: endosteal perimeter0.51.01.4-0.5-0.3-1.01.01.2-1.21.1-1.1-0.9-1.0-0.9-0.9-1.21.01.21.20.9-1.20.9
Epididymis fat weight0.20.81.41.21.11.2-1.1-1.11.1-1.01.01.01.00.70.70.9-0.7-0.8-0.8-0.60.6-0.1
Delta time in closed arm before/after self-admin1.31.23.20.30.6-0.60.81.1-1.11.2-1.1-1.2-1.0-0.7-0.7-1.40.71.41.51.0-1.71.8
Delta time in open arm before/after self-admin4.14.15.21.00.61.9-2.0-2.12.1-2.22.22.12.12.02.02.3-2.0-2.3-2.3-2.12.2-2.0
Diff in mean of infusions in LGA sessions0.20.20.4-0.1-0.0-0.30.30.4-0.40.4-0.4-0.5-0.4-0.6-0.6-0.40.60.50.40.5-0.40.4
Delay discount exponential model param0.80.91.30.90.71.1-1.1-1.11.1-1.01.10.90.90.70.71.1-0.7-1.0-1.0-0.70.9-0.8
Extinction: sum of active levers before priming0.10.20.3-0.3-0.2-0.40.40.4-0.40.6-0.4-0.5-0.3-0.4-0.4-0.40.40.40.40.4-0.40.2
Active lever presses in extinction session 60.40.41.40.60.8-0.10.20.6-0.60.4-0.5-0.7-0.3-0.5-0.5-0.70.50.80.80.6-1.11.2
Bone: final force0.10.21.0-0.3-0.50.1-0.2-0.40.4-0.40.40.30.30.30.30.5-0.2-0.6-0.6-0.40.7-1.0
Bone: final moment0.20.41.1-0.1-0.30.4-0.4-0.60.6-0.60.60.50.50.40.40.7-0.4-0.8-0.8-0.50.9-1.0
Food consumed during 24 hour testing period0.20.30.60.60.60.5-0.5-0.30.3-0.70.30.60.70.80.80.3-0.8-0.2-0.2-0.60.10.2
Glucose0.20.30.5-0.4-0.4-0.50.50.6-0.60.5-0.5-0.4-0.5-0.7-0.7-0.50.60.50.50.5-0.40.2
Heart weight0.71.01.61.31.21.2-1.2-1.21.2-1.20.91.11.10.90.90.9-0.8-0.9-0.8-0.70.60.1
Delay discount hyperbolic model param0.70.71.21.00.91.1-1.1-1.01.0-0.91.00.90.80.70.70.9-0.6-0.8-0.8-0.70.7-0.5
Intermittent access intake day 1-15 change0.30.60.9-0.6-0.4-0.80.80.9-0.90.9-0.8-0.9-0.9-0.9-0.9-0.81.00.80.81.0-0.70.4
Intermittent access intake escalation0.30.71.0-0.7-0.6-0.90.90.9-0.90.9-0.8-0.9-0.9-0.9-0.9-0.81.00.80.80.9-0.70.3
Intermittent access intake escalation 20.20.20.4-0.2-0.1-0.40.40.4-0.40.5-0.4-0.6-0.6-0.5-0.5-0.50.60.50.50.6-0.50.2
Intermitt. access day 1 inactive lever presses0.20.71.0-1.0-0.9-1.01.01.0-1.00.9-0.9-0.8-0.9-0.8-0.8-0.80.90.80.70.8-0.60.2
Intermitt. access day 15 inactive lever presses0.20.30.60.00.2-0.40.40.5-0.50.5-0.5-0.8-0.6-0.7-0.7-0.70.70.70.70.6-0.80.7
Intermitt. access escalation Index0.40.61.00.30.10.7-0.8-0.80.8-0.80.71.00.80.70.71.0-0.8-0.9-1.0-0.81.0-0.6
Intermittent access day 1 total infusions0.10.10.2-0.1-0.20.1-0.2-0.20.2-0.30.30.40.30.50.50.3-0.3-0.3-0.4-0.40.4-0.4
Intermittent access day 15 total infusions0.20.40.6-0.8-0.7-0.70.70.7-0.70.7-0.6-0.6-0.6-0.6-0.6-0.50.70.50.50.6-0.3-0.0
Intermittent access terminal intake (last 3 days)0.00.00.0-0.2-0.2-0.20.20.2-0.20.2-0.1-0.1-0.10.00.0-0.10.10.10.10.1-0.1-0.1
Intermittent access total infusions0.10.10.2-0.3-0.4-0.10.0-0.00.0-0.10.10.30.20.30.30.2-0.2-0.2-0.2-0.30.3-0.4
Intermittent access day 1 locomotion0.20.31.6-1.1-1.3-0.50.40.1-0.10.1-0.10.1-0.00.00.00.10.0-0.3-0.3-0.20.6-1.0
Intermittent access day 15 total locomotion0.20.41.6-0.4-0.60.2-0.3-0.50.5-0.50.60.50.50.50.50.7-0.4-0.8-0.8-0.51.0-1.3
Intermittent access total locomotion0.20.31.1-0.6-0.8-0.1-0.1-0.30.3-0.30.30.40.30.40.40.5-0.3-0.5-0.6-0.40.8-1.1
Intermittent access standard deviation0.10.31.00.40.6-0.10.20.5-0.50.5-0.5-0.3-0.4-0.2-0.2-0.60.30.70.80.4-0.91.0
Left kidney weight0.73.24.82.01.82.2-2.2-2.12.1-1.91.91.81.91.51.51.9-1.6-1.8-1.7-1.21.4-0.7
Right kidney weight0.94.06.62.62.42.5-2.4-2.32.3-2.12.02.12.01.91.91.9-2.1-1.8-1.6-1.51.2-0.3
Cocaine induced anxiety0.00.00.3-0.5-0.5-0.30.20.1-0.10.1-0.1-0.1-0.00.00.0-0.0-0.0-0.0-0.1-0.20.2-0.3
Post-drug Anxiety1.92.02.9-1.4-1.3-1.61.61.4-1.41.4-1.4-1.7-1.6-1.6-1.6-1.41.61.31.21.4-1.00.5
Baseline Anxiety1.31.52.1-0.9-0.7-1.21.21.2-1.21.2-1.2-1.4-1.4-1.4-1.4-1.21.41.21.21.4-1.00.7
Tail length0.41.43.1-0.6-0.90.4-0.6-1.01.0-1.10.91.31.31.31.31.2-1.2-1.4-1.4-1.41.6-1.8
Length with tail0.10.20.9-0.8-0.9-0.30.1-0.20.2-0.20.10.10.40.40.40.3-0.2-0.5-0.4-0.50.7-0.9
Length without tail0.20.52.0-1.4-1.4-1.00.80.6-0.60.6-0.6-0.8-0.6-0.5-0.5-0.40.70.20.20.30.1-0.7
Times rat made contact with spout0.10.10.1-0.4-0.4-0.30.30.2-0.20.2-0.3-0.3-0.2-0.3-0.3-0.20.30.20.20.3-0.1-0.1
Lifetime Intake0.10.10.30.0-0.00.2-0.2-0.20.2-0.20.20.50.30.50.50.2-0.4-0.2-0.2-0.50.2-0.2
Liver weight, left0.30.51.1-0.1-0.30.5-0.6-0.70.7-0.80.70.50.70.30.30.8-0.3-0.9-0.9-0.41.0-1.0
Liver weight, right0.00.10.4-0.3-0.4-0.0-0.0-0.20.2-0.30.2-0.10.3-0.1-0.10.30.1-0.3-0.30.00.4-0.6
Locomotor activity0.61.04.72.12.21.4-1.2-1.01.0-1.10.70.50.80.40.40.5-0.4-0.4-0.2-0.4-0.21.0
Locomotor testing distance1.22.27.02.62.62.0-1.9-1.51.5-1.61.31.11.41.11.11.1-1.1-0.9-0.7-1.00.20.6
Locomotor testing rearing0.40.82.41.51.61.3-1.2-1.01.0-1.00.90.60.90.70.70.7-0.6-0.6-0.5-0.60.20.3
Locomotion in novel chamber0.10.10.30.20.10.4-0.4-0.40.4-0.30.50.60.3-0.2-0.20.50.2-0.4-0.50.10.5-0.6
Locomotion in novel chamber post-restriction0.40.61.1-1.1-1.0-1.00.90.7-0.70.6-0.6-0.8-0.7-0.9-0.9-0.61.00.50.50.8-0.3-0.1
Fecal boli incidents, locomotor time 11.21.86.4-2.4-2.5-1.91.71.2-1.21.3-1.2-1.2-1.3-1.0-1.0-0.91.00.80.60.7-0.1-0.8
Change in fecal boli incidents, locomotor task2.62.66.30.20.7-0.91.21.6-1.61.5-1.7-1.5-1.4-1.6-1.6-1.81.51.92.01.8-2.22.5
Time >=10cm from walls, locomotor time 10.10.10.30.0-0.10.2-0.2-0.30.3-0.30.30.30.30.40.40.3-0.5-0.3-0.3-0.50.4-0.5
Bouts of movement, locomotor time 10.00.00.1-0.2-0.2-0.30.30.3-0.30.2-0.2-0.1-0.3-0.2-0.2-0.20.30.20.20.1-0.20.0
Total resting periods, locomotor time 10.50.60.8-0.6-0.4-0.80.80.9-0.90.8-0.8-0.7-0.8-0.8-0.8-0.80.80.80.80.7-0.80.5
Rest time, locomotor task time 16.78.49.9-2.3-1.8-3.13.13.1-3.13.0-3.1-2.9-2.9-3.0-3.0-3.12.93.03.02.8-2.82.2
Distance moved, locomotor task time 13.95.87.31.61.12.4-2.5-2.72.7-2.52.62.42.52.42.42.7-2.4-2.7-2.7-2.32.5-2.1
Vertical activity count, locomotor time 12.25.36.31.71.32.4-2.5-2.52.5-2.42.52.22.32.42.42.5-2.4-2.4-2.4-2.42.2-1.8
Time >=10cm from walls, locomotor time 20.20.31.81.21.40.8-0.7-0.40.4-0.30.30.40.40.30.30.2-0.3-0.1-0.0-0.2-0.20.6
Bouts of movement, locomotor time 20.00.00.1-0.3-0.3-0.10.1-0.00.0-0.10.10.10.10.20.20.1-0.1-0.1-0.1-0.10.2-0.3
Total resting periods, locomotor time 20.10.10.2-0.5-0.5-0.50.40.4-0.40.3-0.3-0.3-0.3-0.2-0.2-0.30.30.30.20.3-0.20.0
Rest time, locomotor task time 21.72.22.9-0.9-0.6-1.51.61.7-1.71.6-1.6-1.5-1.6-1.3-1.3-1.71.31.71.71.4-1.61.4
Distance moved, locomotor task time 22.32.74.01.71.52.0-2.0-1.91.9-1.71.81.61.71.41.41.8-1.4-1.7-1.7-1.31.4-1.0
Vertical activity count, locomotor time 20.20.30.50.70.60.7-0.7-0.70.7-0.40.60.40.40.40.40.6-0.4-0.5-0.5-0.50.4-0.3
Light reinforcement 10.00.10.20.0-0.00.2-0.2-0.20.2-0.30.20.40.10.20.20.3-0.2-0.2-0.3-0.40.3-0.4
Light reinforcement 20.20.41.01.01.00.7-0.6-0.50.5-0.70.50.70.50.70.70.3-0.8-0.2-0.2-0.4-0.00.4
Bone: marrow area0.20.50.8-0.5-0.4-0.70.70.8-0.80.7-0.8-0.6-0.7-0.9-0.9-0.80.90.80.70.8-0.70.5
Bone: maximum diameter0.10.10.70.80.80.4-0.3-0.10.1-0.20.10.30.20.20.2-0.0-0.20.10.2-0.0-0.30.6
Bone: maximum force0.00.10.3-0.5-0.6-0.20.20.0-0.0-0.00.00.10.10.00.00.1-0.0-0.1-0.2-0.10.3-0.6
Bone: maximum moment0.10.10.4-0.2-0.30.1-0.1-0.20.2-0.30.30.30.30.30.30.3-0.2-0.3-0.4-0.30.4-0.6
Mean time between licks in bursts0.00.00.2-0.4-0.4-0.10.1-0.00.00.10.10.0-0.00.20.20.1-0.2-0.2-0.2-0.20.3-0.4
Mean num. licks in bursts0.20.30.40.20.10.5-0.5-0.60.6-0.50.60.50.50.40.40.6-0.6-0.7-0.7-0.50.7-0.6
Cd content in liver1.31.44.5-2.1-2.1-1.71.51.2-1.21.2-1.2-1.1-1.1-0.9-0.9-0.91.00.60.60.7-0.2-0.7
Co content in liver0.40.50.8-0.2-0.0-0.60.70.8-0.80.8-0.7-0.6-0.9-0.7-0.7-0.80.70.90.90.8-0.90.8
Cu content in liver3.34.05.40.70.21.7-1.8-2.12.1-2.12.12.02.02.12.12.2-2.0-2.3-2.3-2.22.3-2.2
Fe content in liver0.00.00.1-0.2-0.2-0.0-0.0-0.10.1-0.10.1-0.0-0.10.20.20.1-0.2-0.1-0.1-0.20.2-0.3
K content in liver1.21.11.90.30.10.8-0.9-1.11.1-1.01.01.01.01.31.31.1-1.3-1.2-1.2-1.41.2-1.3
Mg content in liver4.95.07.32.01.62.4-2.4-2.32.3-2.32.32.22.22.72.72.2-2.7-2.1-2.1-2.51.8-1.1
Mn content in liver1.61.82.60.3-0.11.0-1.1-1.31.3-1.41.31.51.41.31.31.4-1.5-1.5-1.5-1.61.6-1.5
Na content in liver0.10.10.40.60.60.4-0.3-0.20.2-0.10.20.20.00.30.30.1-0.3-0.0-0.0-0.2-0.10.4
Rb content in liver2.22.57.8-0.9-1.40.5-0.8-1.41.4-1.41.31.21.41.41.41.7-1.4-2.0-2.0-1.82.4-2.8
Se content in liver0.40.51.5-0.5-0.70.1-0.3-0.50.5-0.50.50.70.60.70.70.7-0.8-0.8-0.8-0.91.0-1.2
Sr content in liver0.40.32.01.21.40.6-0.4-0.00.0-0.00.10.30.0-0.1-0.1-0.2-0.10.40.40.3-0.71.2
Zn content in liver3.13.55.62.42.22.3-2.2-1.91.9-1.82.02.01.72.02.01.7-1.9-1.5-1.5-1.71.1-0.2
Bone: minimum diameter0.61.11.6-0.4-0.2-0.91.01.1-1.11.1-1.1-1.0-1.0-1.0-1.0-1.21.01.21.21.0-1.31.1
Time in familiar zone, hab. session 11.11.13.00.10.5-0.70.81.1-1.11.0-1.1-1.0-0.8-0.5-0.5-1.30.61.41.40.8-1.51.7
Time in novel zone, hab. session 10.10.10.3-0.3-0.3-0.20.20.1-0.10.2-0.1-0.1-0.3-0.6-0.6-0.00.50.0-0.00.40.1-0.2
Total zone transitions, hab. session 10.60.91.70.90.81.0-1.0-0.90.9-0.90.91.30.91.01.00.9-1.1-0.8-0.8-1.00.7-0.4
Total locomotion distance, hab. session 10.40.51.40.20.10.4-0.5-0.40.4-0.60.51.00.81.11.10.5-1.2-0.5-0.5-1.10.5-0.4
Locomotion velocity, hab. session 11.01.42.80.50.30.9-1.0-1.01.0-1.11.01.41.31.61.61.0-1.7-1.1-1.1-1.61.0-0.8
Time in familiar zone, hab. session 21.01.01.91.31.31.2-1.1-0.90.9-0.90.91.01.11.31.30.8-1.4-0.7-0.6-1.10.40.2
Time in novel zone, hab. session 20.00.00.10.20.20.1-0.1-0.00.0-0.10.0-0.0-0.1-0.3-0.30.00.30.10.00.3-0.10.1
Total zone transitions, hab. session 21.51.93.11.71.61.7-1.7-1.51.5-1.41.51.51.61.11.11.4-1.2-1.2-1.2-1.10.9-0.3
Total locomotion distance, hab. session 21.21.62.61.61.51.5-1.5-1.21.2-1.31.21.41.51.31.31.1-1.3-1.0-0.9-1.20.6-0.0
Locomotion velocity, hab. session 21.31.72.61.51.41.5-1.5-1.31.3-1.41.31.41.61.31.31.2-1.4-1.1-1.1-1.30.8-0.3
Novel to familiar place preference ratio1.11.23.6-0.6-1.00.3-0.5-0.90.9-1.00.91.00.91.01.01.2-0.9-1.3-1.3-1.31.6-1.9
Novelty place preference0.60.72.1-0.5-0.80.2-0.4-0.60.6-0.70.70.70.70.70.70.8-0.7-1.0-1.0-0.91.2-1.5
Time in novel zone, NPP test0.50.51.5-0.4-0.60.2-0.3-0.50.5-0.70.60.70.60.70.70.8-0.6-0.9-0.9-0.81.0-1.2
Total zone transitions, NPP test0.10.20.90.91.00.6-0.5-0.30.3-0.20.20.30.40.10.10.1-0.1-0.00.0-0.0-0.20.6
Total locomotion distance, NPP test0.50.73.61.81.91.1-0.9-0.40.4-0.50.50.60.80.70.70.2-0.70.00.1-0.4-0.51.2
Locomotion velocity, NPP test0.50.83.51.71.91.1-0.9-0.50.5-0.60.50.60.90.80.80.3-0.7-0.1-0.0-0.5-0.41.1
Intraocular pressure0.10.10.4-0.6-0.6-0.40.40.2-0.20.0-0.2-0.2-0.2-0.1-0.1-0.20.20.10.10.20.0-0.2
Delta distance traveled before/after self-admin1.51.52.01.10.91.4-1.4-1.41.4-1.41.41.21.31.21.21.3-1.2-1.3-1.2-1.21.1-0.8
Delta ambulatory time before/after self-admin0.60.71.00.40.30.8-0.9-0.90.9-1.01.00.91.00.80.81.0-0.8-1.0-1.0-0.90.9-0.9
Parametrial fat weight1.02.43.31.10.81.5-1.6-1.81.8-1.71.61.51.61.61.61.6-1.6-1.7-1.6-1.51.5-1.1
Pavlov. Cond. lever latency0.10.21.00.91.00.5-0.4-0.20.2-0.20.20.30.20.10.10.0-0.10.10.10.0-0.30.7
Pavlov. Cond. magazine entry latency0.00.00.10.30.40.1-0.00.1-0.10.2-0.10.1-0.00.00.0-0.1-0.00.20.20.1-0.30.3
Pavlov. Cond. change in total contacts1.31.43.2-1.8-1.8-1.61.51.2-1.21.3-1.2-1.1-1.2-1.1-1.1-1.01.10.90.80.9-0.5-0.2
Pavlov. Cond. index score0.10.10.1-0.4-0.4-0.40.30.2-0.20.3-0.3-0.2-0.3-0.1-0.1-0.20.20.20.20.1-0.2-0.0
Pavlov. Cond. latency score0.00.00.2-0.4-0.4-0.30.20.1-0.10.2-0.2-0.1-0.2-0.1-0.1-0.10.10.00.00.00.0-0.2
Pavlov. Cond. lever contacts0.10.10.3-0.3-0.4-0.0-0.0-0.20.2-0.20.10.10.10.20.20.3-0.2-0.3-0.3-0.30.4-0.6
Pavlov. Cond. magazine entry number0.00.00.10.30.30.3-0.3-0.30.3-0.40.30.10.20.00.00.2-0.1-0.2-0.2-0.10.2-0.0
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.2-0.30.1-0.2-0.20.2-0.50.30.40.60.30.30.3-0.3-0.4-0.4-0.50.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.4-0.6-0.6-0.60.60.4-0.40.5-0.5-0.4-0.4-0.3-0.3-0.40.30.30.30.3-0.2-0.1
Pavlov. Cond. response bias0.20.20.4-0.6-0.6-0.60.60.5-0.50.6-0.6-0.4-0.4-0.3-0.3-0.50.40.40.40.3-0.30.1
Pavlov. Cond. lever latency1.72.38.7-2.8-2.9-2.11.91.3-1.31.1-1.3-1.2-1.2-1.4-1.4-1.01.50.60.60.90.0-1.1
Pavlov. Cond. magazine entry latency1.41.74.52.12.11.8-1.7-1.31.3-1.11.31.21.21.31.31.1-1.3-0.8-0.8-1.00.40.3
Pavlov. Cond. change in total contacts1.21.96.12.42.52.0-1.8-1.41.4-1.11.31.11.11.21.21.1-1.3-0.8-0.8-0.90.30.6
Pavlov. Cond. index score1.92.67.72.82.82.2-2.0-1.51.5-1.21.51.31.31.51.51.2-1.6-0.9-0.9-1.10.40.6
Pavlov. Cond. latency score1.72.27.82.72.82.1-1.9-1.41.4-1.11.41.21.21.31.31.1-1.4-0.8-0.7-0.90.20.8
Pavlov. Cond. lever contacts1.62.28.02.82.82.1-1.9-1.31.3-1.11.31.21.21.41.41.0-1.5-0.7-0.6-0.90.10.9
Pavlov. Cond. magazine entry number0.70.84.1-1.9-2.0-1.31.10.7-0.70.5-0.7-0.6-0.6-0.7-0.7-0.40.70.20.20.40.2-0.9
Pavlov. Cond. intertrial magazine entries1.52.23.20.60.31.3-1.4-1.51.5-1.71.51.61.61.71.71.6-1.8-1.6-1.6-1.81.6-1.3
Pavlov. Cond. lever-magazine prob. diff.1.82.57.92.82.82.2-2.0-1.51.5-1.21.51.31.31.51.51.2-1.5-0.9-0.8-1.00.30.7
Pavlov. Cond. response bias1.62.28.12.82.92.1-1.9-1.31.3-1.11.31.21.21.41.41.0-1.4-0.7-0.6-0.90.10.9
Time in closed arm before self-admin1.21.52.31.41.31.5-1.5-1.31.3-1.21.21.31.21.11.11.3-1.1-1.1-1.2-1.00.9-0.4
Time in closed arm after self-admin1.01.12.60.20.6-0.50.71.0-1.01.2-1.1-0.9-1.0-0.9-0.9-1.20.91.31.31.1-1.51.6
Time in open arm before self-admin1.21.42.3-1.5-1.4-1.51.41.2-1.21.0-1.1-1.3-1.1-1.2-1.2-1.11.21.01.01.0-0.70.2
Time in open arm after self-admin2.02.23.20.40.01.2-1.3-1.51.5-1.81.71.41.61.51.51.6-1.5-1.7-1.7-1.61.8-1.8
Bone: periosteal estimation0.10.20.70.20.4-0.20.30.5-0.50.4-0.4-0.3-0.4-0.5-0.5-0.50.50.60.60.6-0.70.8
Bone: periosteal perimeter0.10.20.40.20.4-0.20.20.4-0.40.3-0.3-0.3-0.3-0.1-0.1-0.50.20.60.60.3-0.70.7
Bone: post-yield work0.20.20.7-0.2-0.40.1-0.2-0.40.4-0.50.50.50.40.40.40.5-0.5-0.6-0.6-0.50.7-0.9
Progressive ratio test 1 active lever presses0.30.30.7-0.8-0.8-0.80.70.7-0.70.7-0.7-0.4-0.6-0.4-0.4-0.60.50.50.50.4-0.30.1
Progressive ratio test 1 breakpoint0.40.51.0-1.0-1.0-0.90.90.8-0.80.8-0.8-0.5-0.7-0.5-0.5-0.60.60.60.50.5-0.40.0
Progressive ratio test 1 inactive lever presses0.00.00.1-0.1-0.20.0-0.1-0.10.1-0.20.10.20.20.10.10.2-0.2-0.2-0.2-0.10.2-0.1
Progressive ratio test 2 active lever presses0.00.00.2-0.4-0.4-0.20.20.1-0.10.1-0.20.20.10.10.1-0.0-0.1-0.0-0.1-0.00.1-0.2
Progressive ratio test 2 breakpoint0.00.00.2-0.4-0.4-0.20.20.1-0.10.1-0.20.20.10.00.0-0.0-0.1-0.0-0.1-0.00.1-0.2
Progressive ratio test 2 inactive lever presses0.00.00.00.10.10.1-0.00.0-0.0-0.0-0.10.20.10.10.1-0.0-0.10.00.00.0-0.10.2
Incentive Sensitization - Responses0.10.20.50.70.70.6-0.6-0.30.3-0.40.30.60.50.40.40.3-0.5-0.3-0.3-0.20.10.2
Incentive Sensitization - Breakpoint0.20.30.70.80.80.7-0.7-0.50.5-0.50.50.70.60.50.50.5-0.6-0.4-0.4-0.30.20.1
Sum of active levers in priming session hrs 5-60.30.20.80.90.90.7-0.7-0.60.6-0.50.50.50.40.20.20.4-0.2-0.3-0.3-0.20.20.2
Progressive ratio1.92.94.30.3-0.11.3-1.5-1.81.8-1.71.81.91.81.71.71.9-1.7-2.0-2.0-2.02.1-2.0
Food seeking constrained by brief footshock0.10.10.3-0.5-0.5-0.40.40.3-0.30.3-0.3-0.3-0.3-0.2-0.2-0.20.20.20.20.1-0.1-0.1
Seeking ratio, punishment vs. effort0.81.21.90.00.3-0.70.81.1-1.11.1-1.1-1.3-1.0-1.0-1.0-1.21.11.31.31.3-1.41.3
Retroperitoneal fat weight0.73.04.61.10.81.7-1.8-2.22.2-1.81.81.81.81.61.61.9-1.6-2.0-1.9-1.61.8-1.4
Reaction time number correct0.10.20.90.60.80.10.00.3-0.30.4-0.4-0.0-0.2-0.2-0.2-0.40.10.50.60.4-0.81.0
Reaction time mean minus median0.71.78.12.72.81.9-1.7-1.11.1-1.01.11.01.00.80.80.8-0.7-0.4-0.4-0.4-0.20.9
Reaction time mean minus median AUC0.71.77.02.62.71.9-1.7-1.21.2-1.11.21.11.11.01.00.9-0.9-0.6-0.5-0.6-0.00.8
Reaction time num false alarms0.71.01.50.2-0.00.7-0.8-0.90.9-1.11.01.21.11.01.01.0-1.0-1.1-1.1-1.21.1-1.2
Reaction time num false alarms AUC0.91.42.10.40.10.9-1.0-1.11.1-1.41.21.41.31.31.31.2-1.3-1.3-1.2-1.41.3-1.3
Reaction time trials correct on left0.10.20.90.60.80.10.00.3-0.30.4-0.4-0.0-0.2-0.2-0.2-0.40.10.50.60.4-0.81.0
Reaction time trials on left0.10.31.10.70.90.1-0.00.3-0.30.4-0.4-0.1-0.2-0.2-0.2-0.50.20.60.60.4-0.81.1
Reaction time mean0.91.42.51.61.51.6-1.5-1.41.4-1.11.31.11.11.11.11.2-1.0-1.1-1.1-0.90.8-0.4
Reaction time mean AUC0.60.91.41.00.91.2-1.2-1.11.1-0.81.10.80.90.90.91.1-0.8-1.0-1.0-0.80.8-0.6
Median of all reaction times1.01.41.91.10.91.3-1.4-1.41.4-1.01.31.01.01.11.11.3-1.1-1.2-1.2-1.01.1-0.9
Reaction time omissions0.60.93.31.51.80.4-0.20.3-0.30.5-0.3-0.7-0.5-0.7-0.7-0.70.70.91.01.0-1.31.8
Reaction time false alarm rate1.21.72.40.2-0.10.9-1.0-1.21.2-1.51.31.41.41.41.31.4-1.3-1.5-1.4-1.51.5-1.6
Reaction time premature initiation rate0.40.62.71.61.61.1-1.0-0.70.7-0.60.60.50.70.60.60.4-0.6-0.3-0.2-0.3-0.10.6
Reaction time premature initiations0.30.53.41.61.80.9-0.7-0.20.2-0.10.20.20.30.20.2-0.1-0.20.30.40.2-0.71.2
Std. dev. reaction times0.71.34.92.22.21.7-1.5-1.11.1-0.91.10.91.00.80.80.8-0.6-0.6-0.6-0.40.10.4
Reaction time trials completed0.10.31.10.70.90.1-0.00.3-0.30.4-0.4-0.1-0.2-0.2-0.2-0.50.20.60.60.4-0.81.1
Reaction time trials AUC0.10.21.00.81.00.2-0.00.3-0.30.3-0.30.0-0.2-0.2-0.2-0.40.10.50.60.4-0.81.0
Run reversals in cocaine runway, females0.10.10.4-0.5-0.5-0.50.50.3-0.30.4-0.4-0.6-0.4-0.3-0.3-0.40.40.30.30.3-0.20.1
Run reversals in cocaine runway, males0.30.30.8-0.9-0.9-0.80.80.7-0.70.6-0.6-0.4-0.4-0.2-0.2-0.60.20.50.40.1-0.30.1
Latency to leave start box in cocaine runway1.51.72.3-0.7-0.4-1.21.31.3-1.31.4-1.5-1.4-1.3-1.3-1.3-1.51.21.51.51.4-1.51.4
Latency to leave start box in cocaine runway, F0.70.81.0-0.8-0.7-1.01.00.9-0.91.0-1.0-0.9-0.8-0.8-0.8-1.00.70.90.90.8-0.80.6
Latency to leave start box in cocaine runway, M0.80.71.90.30.6-0.40.50.8-0.80.8-0.8-0.8-0.8-0.7-0.7-1.00.71.11.11.0-1.21.4
Std. dev. time between licks in bursts0.30.40.8-0.2-0.40.3-0.4-0.50.5-0.60.60.70.60.40.40.7-0.5-0.7-0.7-0.70.8-0.9
Total sessions with >9 infusions0.20.20.40.70.60.5-0.5-0.30.3-0.40.30.50.40.60.60.3-0.5-0.2-0.2-0.50.10.2
Short access day 1 total inactive lever presses0.70.92.4-1.5-1.5-1.31.21.0-1.00.9-0.9-0.8-0.9-0.9-0.9-0.80.90.70.60.7-0.3-0.3
Short access day 10 total inactive lever presses0.20.60.80.30.10.7-0.7-0.90.9-0.80.90.60.70.80.80.8-0.7-0.8-0.9-0.80.9-0.8
Short access day 1 total infusions0.81.11.91.11.01.1-1.1-1.01.0-1.10.91.21.11.41.40.9-1.3-0.9-0.8-1.20.6-0.1
Short access day 10 total infusions0.30.40.80.80.80.7-0.7-0.50.5-0.50.50.80.60.90.90.5-0.8-0.4-0.4-0.80.20.1
Short access total infusions0.10.10.40.30.30.3-0.3-0.20.2-0.30.20.60.40.60.70.2-0.5-0.2-0.2-0.60.10.1
Short access day 1 locomotion0.10.10.4-0.6-0.6-0.40.40.2-0.20.1-0.2-0.10.20.20.2-0.2-0.10.00.1-0.20.0-0.1
Short access day 10 total locomotion0.10.21.21.01.10.5-0.4-0.20.2-0.20.20.10.30.30.3-0.0-0.20.10.2-0.1-0.40.7
Short access total locomotion0.20.20.4-0.2-0.40.1-0.2-0.40.4-0.40.40.40.50.60.60.5-0.5-0.5-0.5-0.70.6-0.6
One hour access (0.3 mA shock)0.30.31.00.60.8-0.00.20.5-0.50.5-0.4-0.4-0.4-0.4-0.4-0.60.40.80.80.6-1.01.0
Compulsive drug intake0.50.61.0-0.7-0.6-0.80.80.6-0.60.7-0.7-1.0-0.9-1.0-1.0-0.70.90.70.60.9-0.50.4
One hour access (shock baseline)0.10.20.60.50.7-0.00.10.4-0.40.4-0.3-0.2-0.2-0.2-0.2-0.50.30.60.60.4-0.80.8
Social response proportion0.70.81.10.80.71.1-1.1-1.01.0-0.71.00.80.70.90.91.0-0.8-0.9-1.0-0.80.9-0.7
Social responses0.10.20.60.50.70.10.00.3-0.30.3-0.3-0.4-0.4-0.2-0.2-0.30.40.50.50.3-0.60.8
Social time0.40.61.91.41.41.0-0.9-0.70.7-0.70.60.60.70.60.60.5-0.6-0.4-0.3-0.70.10.5
Soleus weight0.00.10.10.20.20.3-0.3-0.30.3-0.30.30.10.3-0.2-0.20.30.1-0.3-0.30.00.3-0.2
Bone: stiffness1.11.84.9-2.2-2.2-1.81.71.4-1.41.3-1.3-1.1-1.3-1.2-1.2-1.11.20.90.81.0-0.4-0.6
Tibialis anterior weight0.20.62.61.61.61.2-1.1-0.80.8-0.70.70.50.70.40.40.6-0.5-0.4-0.4-0.20.10.5
Time to tail flick, vehicle, before self-admin1.51.63.00.40.11.1-1.2-1.41.4-1.21.31.71.20.90.91.5-0.9-1.5-1.6-1.11.6-1.4
Time to tail flick, vehicle, after self-admin0.60.71.0-0.6-0.4-0.80.90.9-0.90.9-1.0-1.0-0.9-0.9-0.9-0.90.90.90.90.9-0.90.8
Time to tail flick, test, before self-admin1.11.22.6-0.1-0.40.7-0.8-1.01.0-0.91.20.91.01.01.01.2-1.0-1.3-1.4-1.21.5-1.6
Time to tail flick, test, after self-admin1.01.01.40.50.31.0-1.0-1.11.1-1.01.11.10.91.11.11.2-1.1-1.1-1.2-1.11.1-0.9
Delta time to tail flick, vehicle, before/after SA3.83.64.8-1.1-0.8-1.92.02.0-2.01.9-2.2-2.2-1.9-1.7-1.7-2.21.72.12.21.9-2.11.8
Delta time to tail flick, test, before/after SA0.10.10.40.60.60.4-0.3-0.20.2-0.30.10.30.20.20.20.1-0.2-0.1-0.0-0.1-0.10.4
Tibia length1.13.04.20.80.51.5-1.6-1.71.7-1.91.81.92.01.91.91.8-1.8-1.9-1.8-1.91.8-1.5
Ambulatory time before self-admin0.60.91.5-1.1-1.0-1.21.21.1-1.11.1-1.0-1.0-1.0-0.8-0.8-1.00.80.90.90.9-0.70.3
Ambulatory time after self-admin0.40.51.5-0.2-0.40.3-0.4-0.60.6-0.60.80.60.80.70.70.7-0.7-0.9-0.8-0.80.9-1.2
Bone: tissue strength0.90.93.11.71.81.3-1.2-0.90.9-0.90.90.80.90.90.90.7-0.8-0.5-0.5-0.60.10.5
Total heroin consumption0.10.20.90.90.90.6-0.5-0.20.2-0.30.50.20.40.20.20.2-0.2-0.1-0.1-0.2-0.10.3
Bone: trabecular number0.50.81.1-0.9-0.8-1.01.00.9-0.90.9-0.9-1.0-0.9-0.9-0.9-0.91.00.80.80.9-0.70.3
Bone: trabecular spacing1.72.22.91.41.21.7-1.7-1.61.6-1.61.61.61.61.51.51.6-1.5-1.5-1.5-1.41.3-0.8
Bone: trabecular thickness0.40.50.7-0.3-0.1-0.60.70.7-0.70.6-0.7-0.7-0.6-0.7-0.7-0.80.60.80.80.7-0.80.8
Bone: trabecular tissue density0.50.84.2-1.7-2.1-0.70.4-0.10.1-0.00.10.30.10.10.10.5-0.1-0.7-0.8-0.51.2-1.9
Water consumed over 24 hours1.31.72.2-0.7-0.4-1.21.31.4-1.41.1-1.4-1.3-1.2-1.4-1.4-1.51.41.51.51.5-1.41.3
Number of responses in last shaping day0.10.10.10.20.20.3-0.3-0.30.3-0.20.30.10.10.20.20.3-0.1-0.2-0.3-0.20.3-0.2