Hub : Genes

Ttl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ttl 0.31 0.14 0.0e+00 0.2 0.2 0.21 0.19 1.7e-21 1.9e-21 2.5e-23 4.2e-21
2 Brain gene expression Ttl 0.07 0.05 1.6e-04 0.02 0.03 0.03 0.02 4.6e-03 2.0e-03 1.9e-03 3.5e-03
3 NAcc alternative TSS XM_039104213.2 0.06 0.04 8.8e-08 0.03 0.03 0.04 0.04 2.3e-05 8.3e-06 6.2e-07 2.3e-06
4 NAcc alternative TSS NM_138536.2 0.06 0.04 1.5e-07 0.02 0.03 0.04 0.04 2.0e-04 1.5e-05 1.3e-06 4.8e-06
5 IC alternative TSS XM_039104213.2 0.32 0.15 3.5e-11 0.2 0.21 0.22 0.24 5.8e-09 2.7e-09 8.1e-10 1.8e-10
6 IC alternative TSS NM_138536.2 0.32 0.15 3.5e-11 0.2 0.21 0.22 0.24 5.8e-09 2.5e-09 7.5e-10 1.4e-10
7 PL gene expression Ttl 0.07 0.05 2.9e-06 0.06 0.05 0.06 0.06 1.7e-07 5.5e-06 9.9e-07 8.8e-07
8 IL gene expression Ttl 0.21 0.16 7.8e-03 0.04 -0 0.01 0.01 4.5e-02 3.8e-01 1.5e-01 2.1e-01
9 BLA alternative TSS NM_138536.2 0.08 0.06 7.4e-04 0.04 0.04 0.03 0.03 2.3e-03 5.8e-03 7.0e-03 8.6e-03
10 BLA alternative TSS XM_039104213.2 0.08 0.06 8.7e-04 0.04 0.03 0.03 0.03 2.9e-03 7.6e-03 9.0e-03 1.2e-02
11 NAcc mRNA stability Ttl 0.04 0.03 5.2e-06 0.03 0.03 0.03 0.03 4.7e-05 1.1e-05 3.9e-05 8.5e-05
12 Brain alternative TSS NM_138536.2 0.19 0.09 5.6e-17 0.18 0.2 0.19 0.19 6.5e-17 6.3e-18 9.1e-18 1.6e-17
13 Brain alternative TSS XM_039104213.2 0.19 0.1 0.0e+00 0.18 0.2 0.19 0.19 4.8e-17 5.2e-18 8.3e-18 1.1e-17
14 LHb gene expression Ttl 0.24 0.15 2.6e-03 0.07 0.01 0.07 0.07 1.0e-02 1.4e-01 1.1e-02 7.6e-03
15 NAcc gene expression Ttl 0.08 0.05 1.9e-12 0.08 0.09 0.07 0.08 7.8e-12 5.5e-13 1.7e-11 5.0e-12
16 pVTA gene expression Ttl 0.06 0.04 1.4e-04 0.04 0.05 0.03 0.04 4.8e-04 1.2e-04 1.0e-03 2.8e-04
17 pVTA alternative TSS XM_039104213.2 0.1 0.06 9.2e-08 0.1 0.09 0.09 0.1 2.6e-08 7.2e-08 5.0e-08 2.0e-08
18 pVTA alternative TSS NM_138536.2 0.1 0.06 1.2e-07 0.1 0.09 0.09 0.1 3.1e-08 7.5e-08 6.7e-08 2.2e-08
19 PL alternative TSS XM_039104213.2 0.03 0.02 1.5e-03 0.01 0.01 0.01 0.02 1.1e-02 1.8e-02 8.4e-03 4.5e-03
20 Liver alternative TSS NM_138536.2 0.06 0.04 1.2e-05 0.03 0.01 0 0.01 1.6e-04 3.2e-02 7.2e-02 6.3e-02
21 PL alternative TSS NM_138536.2 0.03 0.02 2.0e-03 0.01 0.01 0.01 0.01 1.6e-02 2.4e-02 1.4e-02 8.5e-03
22 BLA gene expression Ttl 0.16 0.12 2.6e-05 0.07 0.08 0.07 0.07 1.9e-04 3.9e-05 1.4e-04 1.1e-04
23 Eye mRNA stability Ttl 0.37 0.19 8.2e-03 0.15 0.01 0.03 0.11 2.7e-03 2.5e-01 1.1e-01 9.0e-03
24 Adipose mRNA stability Ttl 0.05 0.04 9.1e-05 0.03 0.02 0.01 0.02 8.0e-04 3.7e-03 1.6e-02 6.3e-03
25 Brain mRNA stability Ttl 0.13 0.07 5.2e-09 0.08 0.09 0.08 0.09 6.9e-08 1.0e-08 4.8e-08 2.0e-08
26 Liver gene expression Ttl 0.13 0.07 2.9e-11 0.04 0.09 0.07 0.08 9.0e-06 1.2e-09 1.2e-08 3.9e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density2.23.85.12.12.02.0-2.02.1-2.12.32.1-2.12.12.1-2.22.2-1.82.1-2.01.9-1.91.9-2.1-1.92.02.21.50.80.3
Area under the delay curve0.30.30.7-0.6-0.7-0.50.5-0.60.6-0.7-0.60.6-0.6-0.70.6-0.60.5-0.60.6-0.50.5-0.30.90.3-0.6-0.6-0.4-0.3-0.2
BMI with tail0.10.21.80.40.40.5-0.50.1-0.10.10.0-0.00.00.30.1-0.1-0.70.1-0.50.1-0.1-0.1-0.30.1-0.5-0.20.81.21.3
BMI without tail0.92.910.42.01.92.4-2.31.2-1.21.21.1-1.11.11.7-0.80.8-2.51.3-2.21.0-1.00.6-1.1-0.6-0.30.82.63.23.2
Body weight2.29.515.43.73.63.9-3.93.2-3.13.13.1-3.03.03.4-2.72.7-3.92.9-3.62.6-2.62.2-2.6-2.21.62.23.43.42.8
Weight adjusted by age3.85.87.72.72.62.5-2.52.7-2.72.82.7-2.62.62.6-2.72.7-2.12.6-2.42.3-2.32.4-2.7-2.42.62.31.70.70.0
Bone surface1.73.04.91.71.71.7-1.71.9-1.91.91.9-1.91.91.8-1.91.9-1.61.9-1.71.8-1.81.8-1.9-1.81.82.21.20.5-0.0
Bone volume1.93.54.71.91.91.8-1.82.0-2.02.12.0-2.02.02.0-2.12.1-1.62.0-1.81.9-1.91.9-2.1-1.92.02.21.20.4-0.1
Breakpoint value in progressive ratio session0.70.81.90.80.81.0-1.00.6-0.60.70.5-0.60.61.0-0.80.7-1.21.0-1.11.2-1.21.0-0.7-1.00.31.01.41.00.8
Number of licking bursts0.20.31.30.70.50.5-0.50.3-0.30.30.3-0.30.30.00.1-0.10.0-0.4-0.1-1.01.0-1.10.21.1-0.1-1.0-0.50.50.8
Context. condit. distance diff. score2.12.54.81.61.91.7-1.72.1-2.12.22.1-2.12.11.6-1.81.9-1.11.4-1.31.0-1.01.1-1.4-1.12.21.00.2-0.2-0.6
Locomotion velocity, session 10.10.10.3-0.5-0.4-0.30.3-0.30.3-0.4-0.30.3-0.3-0.20.1-0.1-0.00.10.20.5-0.50.50.0-0.5-0.10.30.3-0.3-0.5
Locomotion distance, session 11.62.03.11.21.41.3-1.31.6-1.61.61.7-1.71.71.4-1.61.6-1.11.5-1.21.5-1.51.6-1.4-1.61.81.00.7-0.2-0.6
Locomotion velocity, session 20.00.00.2-0.4-0.1-0.00.0-0.10.1-0.4-0.10.1-0.1-0.20.2-0.30.0-0.20.2-0.00.0-0.10.30.1-0.20.2-0.0-0.1-0.1
Locomotion distance, session 23.64.96.82.02.22.1-2.12.4-2.42.32.4-2.42.42.3-2.42.4-2.22.5-2.12.6-2.62.6-2.2-2.62.22.31.80.5-0.2
Locomotion velocity, session 30.40.52.60.50.81.0-0.90.5-0.50.20.4-0.40.40.5-0.00.0-1.00.3-0.80.2-0.20.0-0.1-0.0-0.50.61.21.61.6
Locomotion distance, session 34.54.99.52.62.52.8-2.82.0-2.01.81.9-1.91.92.4-1.61.6-3.02.0-2.71.8-1.81.5-1.8-1.50.51.63.03.12.8
Stereotopy head waving bouts, day 30.70.86.2-0.9-0.7-1.11.1-0.20.2-0.1-0.10.1-0.1-0.6-0.10.21.2-0.21.00.0-0.00.20.2-0.21.00.6-1.4-2.3-2.5
Stereotopy head waving duration, day 31.11.33.0-1.5-1.4-1.61.5-1.11.1-1.0-1.01.0-1.0-1.20.8-0.81.5-1.01.4-0.70.7-0.61.00.6-0.2-0.2-1.4-1.7-1.6
Locomotion velocity, session 71.71.83.41.51.81.8-1.81.7-1.71.71.7-1.71.71.5-1.31.3-1.41.2-1.40.7-0.70.7-1.0-0.71.20.70.80.90.7
Locomotion distance, session 74.45.68.62.72.72.5-2.52.8-2.82.92.8-2.82.82.5-2.72.7-2.12.3-2.31.8-1.81.9-2.6-1.92.71.81.20.70.1
Stereotopy head waving bouts, day 70.40.51.5-0.5-0.4-0.10.1-0.70.7-0.8-0.70.7-0.7-0.50.9-0.9-0.0-0.60.3-0.50.6-0.71.10.7-1.2-0.50.30.81.1
Stereotopy head waving duration, day 70.70.81.9-1.0-0.9-0.70.7-1.11.1-1.2-1.11.1-1.1-0.91.1-1.10.4-0.90.7-0.60.6-0.81.30.8-1.4-0.60.00.30.6
Locomotion velocity, session 81.11.31.80.81.21.1-1.11.3-1.31.21.3-1.31.31.1-1.21.2-1.11.2-1.01.2-1.21.2-1.2-1.21.11.10.80.2-0.1
Locomotion distance, session 87.611.015.23.33.63.4-3.43.9-3.93.93.9-3.93.93.5-3.73.7-3.03.4-3.13.1-3.13.2-3.3-3.23.73.12.00.7-0.3
Degree of sensitization distance0.70.74.5-0.00.1-0.30.30.5-0.60.70.6-0.60.60.0-0.70.70.80.20.4-0.10.10.2-0.4-0.21.6-0.0-1.5-1.9-2.1
Degree of sensitization stereotypy0.40.53.40.40.40.8-0.80.00.0-0.2-0.10.1-0.10.30.3-0.3-1.00.1-0.60.1-0.1-0.10.30.1-1.0-0.01.31.71.8
Conditioned locomotion2.32.74.11.51.51.5-1.51.6-1.61.61.6-1.61.61.7-1.81.8-1.71.9-1.62.0-2.01.9-1.6-1.91.51.71.60.5-0.0
Cocaine response after cond. corrected0.00.00.4-0.1-0.1-0.20.10.0-0.00.00.0-0.00.0-0.1-0.10.10.20.00.20.1-0.10.1-0.1-0.10.30.3-0.3-0.6-0.6
Cocaine response after cond. not corrected0.10.10.3-0.4-0.4-0.50.5-0.30.3-0.3-0.30.3-0.3-0.30.2-0.20.4-0.20.40.0-0.00.00.0-0.0-0.10.0-0.2-0.5-0.6
Cocaine response before conditioning0.30.30.6-0.6-0.7-0.80.8-0.80.8-0.7-0.80.8-0.8-0.50.6-0.60.4-0.40.4-0.20.2-0.30.50.3-0.7-0.60.00.00.1
Saline control response4.25.68.22.62.62.7-2.72.3-2.32.22.3-2.32.32.6-2.22.2-2.92.5-2.72.4-2.42.3-1.9-2.31.52.12.82.11.5
Bone: connectivity density1.01.63.31.31.31.2-1.21.4-1.41.61.4-1.41.41.4-1.41.4-1.11.3-1.31.2-1.21.2-1.3-1.21.31.80.90.40.1
Bone: cortical apparent density0.20.31.2-0.0-0.4-0.10.1-0.60.6-0.6-0.60.6-0.6-0.10.4-0.4-0.40.0-0.20.3-0.30.10.1-0.1-1.0-0.41.11.01.1
Bone: cortical area3.04.66.12.32.22.4-2.42.1-2.12.02.1-2.12.12.3-2.12.1-2.52.3-2.42.3-2.32.2-2.2-2.21.52.02.31.61.1
Bone: cortical porosity2.83.07.5-1.6-1.4-1.11.1-1.91.9-2.0-1.91.9-1.9-1.72.2-2.30.8-1.81.2-1.71.7-1.91.91.9-2.7-1.5-0.21.01.6
Bone: cortical porosity1.21.34.2-1.0-0.8-0.50.5-1.21.2-1.3-1.21.2-1.2-0.91.5-1.50.2-1.10.5-1.01.0-1.21.21.2-2.0-0.70.41.21.6
Bone: cortical thickness0.71.13.41.00.70.9-0.90.6-0.60.40.6-0.60.61.1-0.80.7-1.41.2-1.21.4-1.41.3-1.3-1.30.11.31.81.31.0
Bone: cortical thickness0.10.10.60.20.10.3-0.30.0-0.0-0.1-0.00.0-0.00.20.0-0.1-0.50.2-0.30.3-0.30.2-0.1-0.2-0.40.40.70.80.7
Bone: cortical tissue density0.20.31.1-0.1-0.5-0.20.2-0.70.7-0.7-0.70.7-0.7-0.20.5-0.5-0.3-0.1-0.10.2-0.20.00.2-0.0-1.0-0.50.90.91.0
Condit. Reinf. active minus inactive responses0.30.31.20.60.30.3-0.30.1-0.10.20.1-0.10.10.6-0.40.3-0.70.6-0.70.7-0.70.6-0.7-0.6-0.11.01.10.80.7
Condit. Reinf. active-inactive response ratio0.91.02.51.00.80.8-0.80.8-0.80.80.8-0.80.81.0-1.01.0-1.01.1-1.01.2-1.21.2-1.3-1.20.81.61.10.50.2
Condit. Reinf. active responses0.10.10.50.40.20.2-0.20.1-0.10.10.1-0.10.10.4-0.20.2-0.50.4-0.40.5-0.50.4-0.3-0.4-0.10.50.70.60.5
Condit. Reinf. inactive responses0.00.00.1-0.10.0-0.10.10.2-0.20.00.2-0.20.2-0.0-0.10.10.10.10.10.1-0.10.20.1-0.20.2-0.2-0.1-0.3-0.4
Incentive salience index mean0.30.40.90.70.40.3-0.30.4-0.40.50.4-0.40.40.7-0.70.7-0.50.7-0.70.8-0.80.8-1.0-0.80.50.90.70.30.1
Condit. Reinf. lever presses0.20.20.70.60.50.3-0.20.5-0.50.60.5-0.50.50.5-0.50.6-0.20.4-0.40.3-0.30.4-0.8-0.40.60.40.2-0.0-0.1
Condit. Reinf. active minus inactive responses3.54.55.42.32.32.3-2.32.2-2.22.22.2-2.22.22.3-2.22.2-2.32.3-2.32.3-2.32.2-1.8-2.21.81.82.11.20.6
Condit. Reinf. active-inactive response ratio3.74.35.62.42.32.3-2.32.3-2.32.32.2-2.22.22.3-2.22.2-2.22.1-2.21.9-1.91.8-1.9-1.81.81.71.81.20.7
Condit. Reinf. active responses4.05.67.92.52.42.6-2.62.3-2.32.22.3-2.32.32.6-2.42.3-2.82.6-2.62.7-2.72.6-1.8-2.61.72.02.71.71.0
Condit. Reinf. inactive responses0.40.51.00.50.60.7-0.70.6-0.60.40.6-0.60.60.7-0.60.6-0.90.8-0.71.0-1.01.0-0.3-1.00.41.01.00.50.3
Condit. Reinf. lever presses1.01.32.21.41.31.4-1.41.1-1.11.11.1-1.11.11.3-1.11.1-1.51.2-1.31.1-1.11.1-0.6-1.10.70.61.41.10.9
Condit. Reinf. lever reinforcers received3.44.76.12.32.32.4-2.42.2-2.22.12.2-2.22.22.4-2.22.2-2.52.4-2.42.4-2.42.3-1.7-2.31.71.82.31.40.8
Conditioned reinforcement - actives0.10.21.30.60.30.5-0.5-0.20.20.0-0.20.0-0.00.20.1-0.2-0.5-0.0-0.4-0.10.1-0.30.00.3-0.5-0.50.51.01.1
Conditioned reinforcement - inactives1.82.64.41.51.51.2-1.21.6-1.61.91.6-1.61.61.6-1.91.9-1.21.7-1.32.0-2.01.9-2.0-1.92.11.40.9-0.4-0.9
Conditioned locomotion0.10.10.70.40.20.4-0.3-0.00.00.2-0.0-0.00.00.10.1-0.1-0.3-0.1-0.3-0.20.2-0.20.00.2-0.3-0.40.30.70.8
Patch foraging indifference point 0 sec0.61.12.50.50.70.6-0.61.3-1.30.91.3-1.21.20.8-1.21.2-0.41.0-0.51.0-1.01.3-0.9-1.31.61.5-0.0-0.9-1.3
Patch foraging indifference point AUC0.50.81.51.01.01.0-1.00.8-0.81.00.8-0.80.81.0-0.90.9-1.01.0-1.00.9-0.90.7-1.2-0.70.60.41.00.70.5
Delay disc. indifference point, 0s delay3.94.35.9-2.4-2.4-2.42.4-2.32.3-2.3-2.32.2-2.2-2.32.1-2.12.3-2.12.3-1.81.8-1.82.01.8-1.7-1.7-1.9-1.5-1.0
Delay disc. indifference point, 16s delay0.20.30.4-0.4-0.5-0.60.5-0.40.4-0.4-0.40.4-0.4-0.60.5-0.40.6-0.60.6-0.60.6-0.40.60.4-0.2-0.6-0.6-0.6-0.4
Delay disc. indifference point, 2s delay0.10.10.4-0.4-0.3-0.30.3-0.30.3-0.3-0.30.2-0.2-0.40.3-0.30.4-0.40.4-0.40.4-0.30.60.3-0.2-0.4-0.5-0.4-0.3
Delay disc. indifference point, 24s delay0.81.01.4-1.1-1.1-1.01.0-1.01.0-1.1-1.01.0-1.0-1.11.0-1.01.1-1.01.1-0.80.8-0.71.20.7-0.7-0.8-1.0-0.9-0.7
Delay disc. indifference point, 4s delay0.10.10.3-0.2-0.10.1-0.1-0.20.2-0.3-0.30.2-0.2-0.10.3-0.3-0.1-0.20.0-0.10.1-0.00.30.0-0.5-0.20.30.50.5
Delay disc. indifference point, 8s delay0.30.41.1-0.4-0.5-0.30.3-0.60.6-0.7-0.60.6-0.6-0.60.7-0.70.4-0.70.5-0.80.8-0.61.00.6-0.7-0.9-0.40.10.3
Indifference point function ln k0.40.71.60.70.80.8-0.71.0-1.00.81.0-1.01.00.8-0.90.9-0.70.8-0.70.8-0.80.9-0.6-0.90.91.20.40.1-0.1
Indifference point function log k0.40.71.60.70.80.8-0.71.0-1.00.81.0-1.01.00.8-0.90.9-0.70.8-0.70.8-0.80.9-0.6-0.90.91.20.40.1-0.1
Patch foraging total patch changes 0 sec0.71.32.90.60.90.7-0.71.4-1.41.01.4-1.31.30.9-1.31.3-0.51.1-0.61.1-1.11.3-1.0-1.41.71.60.1-0.9-1.3
Patch foraging total patch changes 12 sec0.00.00.3-0.00.10.2-0.20.2-0.2-0.00.2-0.20.20.2-0.10.1-0.30.3-0.20.3-0.30.2-0.1-0.30.10.50.30.10.0
Patch foraging total patch changes 18 sec0.20.32.6-0.3-0.0-0.30.30.4-0.40.30.4-0.40.4-0.2-0.30.30.6-0.00.5-0.10.1-0.0-0.2-0.01.0-0.1-1.1-1.5-1.6
Patch foraging total patch changes 24 sec0.50.85.4-0.10.2-0.30.20.7-0.80.60.8-0.70.7-0.0-0.70.70.80.10.5-0.00.00.2-0.7-0.21.70.1-1.5-2.1-2.3
Patch foraging total patch changes 6 sec1.32.03.31.21.41.2-1.21.7-1.71.51.7-1.61.61.3-1.61.6-1.01.5-1.11.3-1.31.5-1.7-1.51.81.80.5-0.3-0.8
Patch foraging time to switch 0 sec3.67.49.5-2.8-2.8-2.72.7-2.92.9-3.0-2.92.9-2.9-2.93.1-3.12.5-3.02.6-2.92.9-3.02.83.0-2.9-2.4-1.9-0.60.2
Patch foraging water rate 0 sec4.810.012.13.33.33.1-3.13.4-3.43.43.4-3.43.43.3-3.53.5-3.13.4-3.13.4-3.43.4-3.4-3.33.22.92.51.00.1
Patch foraging water rate 12 sec1.02.13.31.41.71.4-1.41.8-1.81.71.8-1.81.81.5-1.61.6-1.21.4-1.31.3-1.31.3-1.7-1.31.70.60.80.2-0.2
Patch foraging water rate 18 sec0.30.50.90.90.80.8-0.80.6-0.60.60.6-0.60.60.7-0.60.6-0.90.7-0.80.7-0.70.7-0.7-0.60.30.80.90.80.6
Patch foraging water rate 24 sec0.60.81.21.11.11.1-1.01.0-1.00.71.0-0.90.90.9-0.70.7-1.10.8-1.00.7-0.70.8-0.9-0.80.40.61.01.00.8
Patch foraging water rate 6 sec2.13.03.91.82.02.0-2.01.9-1.91.81.8-1.81.81.9-1.71.7-1.91.8-1.91.8-1.81.6-1.7-1.61.31.31.61.20.8
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.5-0.4-0.50.5-0.30.3-0.4-0.30.4-0.4-0.40.3-0.30.5-0.40.4-0.40.4-0.30.40.3-0.2-0.4-0.5-0.4-0.3
Distance traveled before self-admin5.26.88.12.92.82.8-2.82.7-2.72.82.7-2.72.72.8-2.92.9-2.72.8-2.72.7-2.72.7-2.5-2.72.52.52.21.10.4
Distance traveled after self-admin1.41.73.11.61.61.8-1.81.3-1.31.51.2-1.31.31.5-1.21.2-1.61.3-1.61.0-1.00.9-1.1-0.90.81.21.21.31.1
Extensor digitorum longus weight0.00.20.70.60.50.6-0.60.3-0.30.30.3-0.30.30.3-0.10.1-0.30.0-0.4-0.20.2-0.4-0.00.4-0.0-0.60.20.70.8
Bone: elastic displacement0.60.72.1-0.4-0.5-0.30.3-0.90.9-0.9-0.90.9-0.9-0.61.0-1.00.1-0.70.3-0.80.8-0.90.90.9-1.5-0.60.31.01.3
Bone: elastic work0.20.31.0-0.2-0.4-0.20.2-0.60.6-0.6-0.60.6-0.6-0.30.7-0.7-0.0-0.40.1-0.40.4-0.50.50.5-1.0-0.40.40.81.0
Bone: endosteal estimation1.32.85.11.82.22.1-2.12.2-2.22.22.2-2.22.21.8-1.81.8-1.51.5-1.61.0-1.01.0-1.3-1.01.90.80.60.50.1
Bone: endosteal perimeter2.96.18.42.72.72.7-2.72.7-2.72.92.7-2.72.72.7-2.72.7-2.42.6-2.52.3-2.32.3-2.3-2.32.52.01.81.00.4
Epididymis fat weight0.30.91.2-0.8-1.0-0.90.9-1.01.0-1.0-1.11.0-1.0-1.01.0-1.00.9-1.00.9-1.01.0-1.11.01.1-0.9-0.7-0.8-0.30.0
Delta time in closed arm before/after self-admin0.40.40.7-0.6-0.5-0.40.4-0.40.4-0.7-0.40.5-0.5-0.70.7-0.70.6-0.70.7-0.90.9-0.80.90.8-0.6-0.8-0.7-0.2-0.0
Delta time in open arm before/after self-admin1.11.11.80.80.90.7-0.71.1-1.11.21.1-1.01.01.1-1.31.3-0.81.2-0.91.3-1.31.3-1.4-1.31.31.30.6-0.2-0.6
Diff in mean of infusions in LGA sessions0.30.40.8-0.9-0.7-0.60.6-0.80.8-0.4-0.80.8-0.8-0.60.5-0.50.6-0.60.7-0.50.5-0.50.60.5-0.4-0.3-0.6-0.6-0.4
Delay discount exponential model param0.30.30.70.60.60.5-0.50.6-0.60.70.6-0.50.50.6-0.60.6-0.40.6-0.60.5-0.50.3-0.8-0.30.60.50.30.20.1
Extinction: sum of active levers before priming0.10.10.5-0.1-0.00.1-0.1-0.20.2-0.3-0.20.1-0.10.10.1-0.1-0.30.1-0.20.3-0.30.2-0.1-0.2-0.50.40.70.60.6
Active lever presses in extinction session 60.10.10.4-0.3-0.1-0.20.2-0.20.20.0-0.10.0-0.0-0.0-0.20.20.10.10.10.4-0.40.5-0.1-0.50.30.10.0-0.5-0.6
Bone: final force3.04.96.42.42.42.5-2.52.3-2.32.32.3-2.32.32.4-2.22.2-2.52.3-2.42.2-2.22.1-2.2-2.11.62.02.21.61.1
Bone: final moment2.43.95.22.12.22.3-2.32.1-2.12.12.1-2.12.12.1-1.91.9-2.22.0-2.21.9-1.91.8-2.0-1.81.51.71.91.40.9
Food consumed during 24 hour testing period0.20.31.3-0.5-0.5-0.70.7-0.30.3-0.1-0.30.3-0.3-0.50.2-0.20.9-0.50.7-0.60.5-0.40.20.40.3-0.4-1.2-1.1-1.0
Glucose0.20.30.50.60.60.6-0.50.7-0.70.70.7-0.70.70.6-0.60.6-0.50.6-0.60.4-0.40.5-0.6-0.50.60.30.30.20.0
Heart weight8.012.415.83.63.83.5-3.54.0-4.04.04.0-3.93.93.8-4.04.0-3.13.8-3.53.4-3.43.4-3.9-3.43.73.72.31.00.0
Delay discount hyperbolic model param0.20.30.70.60.60.4-0.40.6-0.60.60.6-0.50.50.6-0.60.6-0.40.6-0.60.5-0.50.3-0.8-0.30.50.50.40.30.1
Intermittent access intake day 1-15 change0.10.31.10.90.50.6-0.50.3-0.30.30.3-0.30.30.6-0.30.3-0.70.4-0.70.3-0.30.2-0.4-0.2-0.10.40.81.01.0
Intermittent access intake escalation0.10.31.50.80.40.5-0.50.2-0.20.20.1-0.10.10.5-0.20.1-0.60.3-0.70.2-0.20.1-0.3-0.0-0.30.10.81.21.2
Intermittent access intake escalation 20.20.21.30.60.30.4-0.30.0-0.0-0.00.0-0.00.00.4-0.00.0-0.60.2-0.60.2-0.20.1-0.3-0.1-0.40.00.81.11.1
Intermitt. access day 1 inactive lever presses0.72.73.61.81.81.6-1.61.8-1.81.81.8-1.71.71.7-1.81.8-1.61.7-1.71.8-1.81.6-1.9-1.61.61.41.40.70.2
Intermitt. access day 15 inactive lever presses1.12.36.11.31.41.0-1.01.9-1.92.01.9-1.81.81.3-1.91.9-0.71.4-0.91.3-1.31.3-1.7-1.32.51.1-0.1-1.1-1.6
Intermitt. access escalation Index0.20.31.00.60.60.6-0.50.6-0.60.30.6-0.30.30.5-0.30.2-0.70.4-0.70.3-0.30.2-0.5-0.2-0.10.50.91.01.0
Intermittent access day 1 total infusions0.00.00.20.50.20.2-0.20.1-0.10.30.0-0.10.10.1-0.00.0-0.20.0-0.2-0.00.0-0.0-0.20.0-0.1-0.40.20.40.4
Intermittent access day 15 total infusions0.40.61.71.30.90.9-0.90.7-0.70.80.7-0.70.70.9-0.70.7-0.90.7-1.00.5-0.50.4-0.9-0.40.40.20.81.00.9
Intermittent access terminal intake (last 3 days)0.60.81.71.31.00.8-0.80.9-0.91.00.9-0.80.81.0-1.01.0-0.90.9-1.00.8-0.80.8-1.2-0.80.80.50.80.60.4
Intermittent access total infusions0.80.91.81.31.11.0-1.01.0-1.01.11.0-1.01.01.1-1.01.0-1.00.9-1.00.8-0.80.8-1.1-0.80.90.60.70.60.4
Intermittent access day 1 locomotion0.81.02.01.41.31.1-1.11.0-1.01.41.0-1.11.11.1-1.01.0-1.00.9-1.10.8-0.80.7-1.2-0.70.90.40.70.60.4
Intermittent access day 15 total locomotion0.81.42.21.21.00.8-0.81.0-1.01.41.0-1.01.01.2-1.41.4-1.01.3-1.01.5-1.51.5-1.5-1.51.41.30.8-0.1-0.5
Intermittent access total locomotion1.82.13.61.91.71.5-1.51.5-1.51.81.5-1.51.51.6-1.61.6-1.51.5-1.61.4-1.41.3-1.7-1.31.41.11.20.80.4
Intermittent access standard deviation0.20.41.11.10.80.6-0.60.8-0.80.70.8-0.70.70.8-0.70.7-0.60.6-0.80.4-0.40.4-0.9-0.30.60.20.50.60.5
Left kidney weight0.63.08.91.01.30.9-0.92.0-2.02.02.1-2.02.01.3-2.12.2-0.41.6-0.71.5-1.51.7-1.6-1.73.01.7-0.5-1.8-2.5
Right kidney weight0.62.78.40.91.20.9-0.91.9-1.92.02.0-2.02.01.2-2.12.1-0.41.5-0.71.3-1.31.6-1.4-1.62.91.9-0.6-1.8-2.4
Cocaine induced anxiety2.53.67.4-2.1-2.0-2.32.3-1.61.6-1.5-1.61.5-1.5-2.01.4-1.42.4-1.82.3-1.81.8-1.61.51.6-0.4-1.5-2.7-2.7-2.4
Post-drug Anxiety2.12.24.4-1.6-1.6-1.81.8-1.31.3-1.3-1.21.3-1.3-1.61.2-1.11.9-1.51.8-1.41.4-1.41.21.4-0.4-1.2-2.1-2.0-1.7
Baseline Anxiety0.10.10.60.50.40.5-0.50.3-0.30.20.3-0.20.20.4-0.20.2-0.50.3-0.50.2-0.20.1-0.2-0.1-0.10.20.60.80.8
Tail length3.011.717.84.04.04.2-4.23.8-3.83.63.7-3.73.73.7-3.33.3-3.93.4-3.82.9-2.92.6-3.1-2.62.52.83.22.82.1
Length with tail5.322.830.35.45.45.5-5.55.2-5.25.05.2-5.15.15.2-4.84.8-5.24.9-5.24.4-4.44.3-4.5-4.33.94.44.33.22.1
Length without tail2.68.410.23.03.02.9-2.93.2-3.23.13.2-3.23.23.1-3.23.2-2.83.1-2.93.0-3.03.1-2.9-3.12.92.92.20.90.1
Times rat made contact with spout0.00.00.1-0.2-0.2-0.20.2-0.20.2-0.1-0.20.2-0.2-0.20.1-0.10.2-0.20.2-0.10.1-0.10.10.10.00.3-0.3-0.3-0.3
Lifetime Intake0.70.91.71.31.11.0-1.01.0-1.01.11.0-1.01.01.0-1.01.0-1.00.9-1.00.9-0.90.8-1.1-0.80.90.70.70.50.3
Liver weight, left1.32.13.11.61.71.7-1.71.7-1.71.81.7-1.71.71.5-1.61.6-1.41.4-1.41.2-1.21.2-1.3-1.21.61.10.80.40.0
Liver weight, right0.20.30.70.80.60.6-0.60.5-0.50.60.5-0.60.60.7-0.70.7-0.60.6-0.60.5-0.50.6-0.6-0.60.60.40.40.30.1
Locomotor activity0.40.71.30.80.90.9-0.90.9-0.90.50.9-0.80.80.9-0.70.7-1.00.9-1.00.7-0.70.7-0.7-0.70.31.11.00.90.7
Locomotor testing distance0.10.20.50.20.40.2-0.10.7-0.70.30.7-0.60.60.3-0.50.5-0.10.4-0.20.3-0.30.5-0.5-0.50.60.7-0.0-0.3-0.5
Locomotor testing rearing1.12.23.91.21.41.2-1.21.7-1.71.51.7-1.71.71.4-1.61.6-1.11.6-1.21.5-1.51.8-1.5-1.81.72.00.9-0.0-0.5
Locomotion in novel chamber0.30.41.50.90.91.0-1.00.5-0.50.60.5-0.50.50.7-0.30.3-0.90.4-0.80.0-0.00.2-0.3-0.2-0.00.10.71.21.2
Locomotion in novel chamber post-restriction0.30.42.30.50.60.8-0.80.3-0.30.20.3-0.30.30.6-0.10.1-1.00.5-0.80.4-0.40.3-0.2-0.3-0.50.41.21.51.5
Fecal boli incidents, locomotor time 10.20.30.9-0.5-0.5-0.40.4-0.60.6-0.7-0.60.7-0.7-0.50.7-0.70.2-0.60.3-0.40.4-0.60.60.7-0.9-0.50.10.40.6
Change in fecal boli incidents, locomotor task0.00.00.1-0.4-0.3-0.30.3-0.30.3-0.3-0.30.2-0.2-0.20.1-0.10.2-0.10.20.0-0.00.10.1-0.1-0.10.2-0.1-0.3-0.3
Time >=10cm from walls, locomotor time 10.20.21.50.40.40.6-0.60.1-0.10.10.1-0.30.30.20.2-0.2-0.5-0.0-0.4-0.20.2-0.30.20.3-0.5-0.40.51.11.2
Bouts of movement, locomotor time 14.04.67.1-2.5-2.6-2.52.5-2.62.6-2.5-2.62.7-2.7-2.32.2-2.22.1-2.02.2-1.61.6-1.51.91.6-2.0-1.7-1.4-1.2-0.7
Total resting periods, locomotor time 14.04.47.2-2.4-2.6-2.42.4-2.52.5-2.4-2.52.7-2.7-2.32.3-2.32.0-2.02.1-1.61.6-1.61.91.6-2.2-1.7-1.3-0.9-0.5
Rest time, locomotor task time 10.60.81.4-0.9-1.0-0.80.8-1.01.0-1.0-1.01.2-1.2-1.01.0-1.00.7-0.90.9-0.90.9-0.80.90.8-1.0-0.9-0.6-0.10.1
Distance moved, locomotor task time 10.00.00.10.10.2-0.10.10.1-0.10.10.1-0.30.30.1-0.10.10.10.0-0.0-0.10.1-0.1-0.20.10.1-0.1-0.1-0.1-0.0
Vertical activity count, locomotor time 10.10.30.70.50.70.5-0.50.7-0.70.80.7-0.80.80.6-0.60.6-0.40.5-0.50.4-0.40.3-0.5-0.30.70.50.20.1-0.0
Time >=10cm from walls, locomotor time 20.10.10.30.40.50.5-0.50.4-0.40.40.4-0.50.50.2-0.00.1-0.2-0.1-0.2-0.40.4-0.40.10.40.0-0.5-0.10.50.6
Bouts of movement, locomotor time 20.91.52.7-1.0-1.1-0.91.0-1.21.2-1.3-1.21.3-1.3-1.21.5-1.50.9-1.31.0-1.31.3-1.41.41.4-1.6-1.4-0.50.30.8
Total resting periods, locomotor time 20.91.53.2-0.9-1.1-0.90.9-1.31.3-1.4-1.31.4-1.4-1.21.5-1.50.8-1.30.9-1.31.3-1.31.41.4-1.8-1.4-0.40.61.0
Rest time, locomotor task time 20.70.92.2-0.9-1.1-0.90.9-1.31.3-1.2-1.31.4-1.4-0.91.2-1.20.5-0.80.7-0.50.5-0.60.90.6-1.5-0.50.00.40.6
Distance moved, locomotor task time 20.20.31.00.10.30.1-0.10.6-0.60.50.6-0.80.80.2-0.60.60.20.3-0.00.1-0.10.2-0.5-0.21.00.3-0.5-0.9-1.0
Vertical activity count, locomotor time 20.40.61.60.40.80.5-0.51.0-1.00.91.0-1.11.10.6-0.90.9-0.20.6-0.40.4-0.50.4-0.7-0.41.30.6-0.2-0.6-0.8
Light reinforcement 10.30.91.61.01.21.3-1.31.0-1.01.01.0-1.01.01.0-0.80.8-1.20.9-1.00.7-0.70.6-0.4-0.60.60.71.00.90.7
Light reinforcement 20.20.30.70.80.70.7-0.70.5-0.50.70.5-0.60.60.6-0.60.6-0.70.5-0.60.5-0.50.2-0.4-0.20.50.50.60.40.4
Bone: marrow area1.32.85.01.82.12.0-2.02.2-2.22.22.2-2.22.21.7-1.81.8-1.41.5-1.61.0-1.01.1-1.3-1.12.00.90.60.40.1
Bone: maximum diameter4.58.410.43.03.13.2-3.23.1-3.13.13.0-3.03.03.1-3.03.0-3.13.1-3.02.9-2.92.9-2.8-2.92.52.82.61.60.8
Bone: maximum force1.01.82.11.41.41.4-1.41.5-1.51.41.5-1.51.51.4-1.41.4-1.31.4-1.41.4-1.41.3-1.4-1.31.21.31.10.60.2
Bone: maximum moment0.61.01.41.01.11.0-1.01.2-1.21.11.2-1.21.21.1-1.11.1-0.91.1-1.01.0-1.01.0-1.1-1.01.00.90.70.30.0
Mean time between licks in bursts0.20.40.9-0.7-0.6-0.40.4-0.70.7-0.8-0.70.7-0.7-0.60.8-0.80.3-0.70.5-0.70.7-0.80.80.8-0.9-0.3-0.20.30.5
Mean num. licks in bursts0.30.41.6-0.7-0.5-0.60.6-0.30.3-0.2-0.20.2-0.2-0.1-0.30.30.10.50.21.0-1.11.2-0.3-1.20.41.30.2-1.0-1.3
Cd content in liver1.71.93.41.71.41.6-1.61.2-1.21.31.1-1.21.21.5-1.21.2-1.71.4-1.71.2-1.21.1-1.1-1.10.61.81.71.71.4
Co content in liver1.61.93.61.51.51.8-1.81.2-1.21.21.2-1.21.21.5-1.11.0-1.91.3-1.71.2-1.21.0-0.9-1.00.40.91.81.81.6
Cu content in liver2.12.54.71.91.71.9-1.91.4-1.41.41.4-1.41.41.8-1.41.3-2.11.6-2.01.6-1.61.4-1.2-1.40.60.82.21.91.6
Fe content in liver0.20.20.50.60.50.7-0.70.5-0.50.40.5-0.40.40.5-0.30.3-0.70.4-0.60.5-0.50.30.2-0.30.10.20.70.70.6
K content in liver0.70.60.90.80.80.8-0.80.8-0.80.60.8-0.70.70.8-0.80.8-0.90.9-0.81.0-1.00.9-0.9-0.90.50.80.90.50.3
Mg content in liver2.32.34.21.71.61.8-1.81.4-1.41.21.3-1.31.31.6-1.31.3-2.01.5-1.81.6-1.61.4-1.4-1.40.61.22.11.71.4
Mn content in liver2.73.04.41.82.02.0-2.01.8-1.81.61.7-1.71.71.9-1.61.6-2.11.8-1.91.7-1.71.6-1.5-1.61.11.62.01.51.1
Na content in liver0.10.10.7-0.3-0.2-0.30.30.0-0.0-0.10.00.1-0.1-0.30.1-0.10.5-0.30.5-0.20.2-0.20.30.20.3-0.4-0.7-0.9-0.9
Rb content in liver2.93.45.41.91.81.9-1.91.6-1.61.61.5-1.61.62.0-1.81.8-2.22.0-2.12.2-2.22.0-1.8-2.01.12.02.31.51.0
Se content in liver1.82.12.81.71.61.6-1.61.5-1.51.51.5-1.51.51.6-1.51.5-1.61.6-1.61.6-1.61.4-1.2-1.41.10.91.61.10.7
Sr content in liver0.80.71.41.11.21.2-1.21.1-1.11.01.0-1.01.00.8-0.70.7-0.80.6-0.90.2-0.20.2-0.6-0.20.60.40.40.70.6
Zn content in liver0.60.71.91.00.70.8-0.80.6-0.60.50.5-0.50.50.9-0.60.6-1.10.9-1.01.0-1.00.9-0.9-0.90.10.41.41.11.0
Bone: minimum diameter1.42.53.61.71.71.9-1.91.7-1.71.61.7-1.71.71.7-1.51.5-1.81.6-1.71.5-1.51.5-1.5-1.51.21.51.51.10.7
Time in familiar zone, hab. session 10.70.71.2-0.9-0.7-0.70.7-0.80.8-0.7-0.80.8-0.8-0.90.9-0.90.8-1.00.9-1.11.1-1.00.91.0-0.7-1.1-0.8-0.3-0.1
Time in novel zone, hab. session 10.90.91.70.90.70.6-0.60.9-0.91.10.9-0.90.90.9-1.21.2-0.61.1-0.81.1-1.21.2-1.1-1.21.31.10.4-0.3-0.7
Total zone transitions, hab. session 11.41.92.61.31.41.4-1.51.6-1.61.51.6-1.61.61.4-1.51.5-1.31.5-1.21.5-1.51.5-1.1-1.51.51.00.90.1-0.3
Total locomotion distance, hab. session 12.13.05.61.41.71.6-1.62.1-2.11.92.2-2.22.21.6-2.02.0-1.21.8-1.31.7-1.71.8-1.4-1.82.41.40.5-0.6-1.2
Locomotion velocity, hab. session 12.23.05.41.41.71.6-1.62.1-2.11.82.2-2.22.21.6-2.02.0-1.31.8-1.31.8-1.81.9-1.5-1.92.31.50.6-0.5-1.1
Time in familiar zone, hab. session 20.80.81.3-1.0-1.1-1.11.1-1.01.0-0.8-0.90.9-0.9-1.00.8-0.81.1-0.91.0-0.70.7-0.70.60.7-0.5-0.8-1.0-1.0-0.8
Time in novel zone, hab. session 20.80.81.40.91.11.2-1.21.0-1.00.80.9-0.90.90.9-0.70.7-1.10.8-1.00.7-0.60.6-0.5-0.60.40.91.01.00.8
Total zone transitions, hab. session 22.63.35.12.12.02.2-2.21.8-1.81.71.8-1.81.82.0-1.71.7-2.31.9-2.01.8-1.81.7-1.6-1.71.10.82.11.61.2
Total locomotion distance, hab. session 23.44.47.11.82.01.7-1.72.3-2.32.32.4-2.42.42.1-2.52.5-1.62.3-1.72.4-2.42.5-2.2-2.52.71.61.1-0.4-1.1
Locomotion velocity, hab. session 22.73.76.81.51.61.3-1.32.1-2.12.12.1-2.12.11.8-2.32.3-1.22.1-1.42.2-2.32.4-2.1-2.42.61.60.8-0.8-1.5
Novel to familiar place preference ratio0.10.10.80.10.1-0.00.00.4-0.40.40.4-0.40.40.1-0.40.40.30.10.10.1-0.10.1-0.2-0.10.70.3-0.6-0.8-0.9
Novelty place preference0.10.10.7-0.2-0.1-0.30.30.1-0.10.10.1-0.10.1-0.2-0.10.10.5-0.20.4-0.30.3-0.20.10.20.50.0-0.8-0.8-0.9
Time in novel zone, NPP test0.10.10.6-0.10.0-0.10.10.2-0.20.30.2-0.20.2-0.1-0.20.20.3-0.10.2-0.10.1-0.10.00.10.50.1-0.6-0.7-0.8
Total zone transitions, NPP test0.60.81.51.11.11.2-1.21.0-1.01.01.0-1.01.01.0-0.90.9-1.10.9-1.00.8-0.80.7-0.8-0.70.70.10.80.70.5
Total locomotion distance, NPP test3.24.48.31.92.11.8-1.82.5-2.52.52.5-2.52.52.0-2.52.5-1.42.2-1.62.1-2.12.2-2.1-2.22.91.60.7-0.6-1.3
Locomotion velocity, NPP test2.33.26.71.61.71.5-1.52.1-2.12.22.2-2.22.21.7-2.22.2-1.11.8-1.31.7-1.71.9-1.8-1.92.61.20.3-0.7-1.3
Intraocular pressure0.10.21.00.20.30.5-0.50.1-0.1-0.00.1-0.10.10.10.2-0.2-0.3-0.2-0.2-0.40.4-0.40.20.4-0.5-0.70.20.81.0
Delta distance traveled before/after self-admin0.80.91.7-0.8-0.7-0.60.6-1.11.1-0.8-1.11.0-1.0-0.81.1-1.10.5-1.00.6-1.11.1-1.30.91.3-1.3-0.8-0.40.50.8
Delta ambulatory time before/after self-admin3.44.25.7-2.2-2.0-2.02.0-2.22.2-2.1-2.22.1-2.1-2.12.3-2.31.9-2.22.0-2.32.3-2.42.02.4-2.2-2.0-1.6-0.50.1
Parametrial fat weight0.51.22.2-0.8-1.0-0.90.9-1.31.3-1.2-1.31.3-1.3-1.11.3-1.30.9-1.21.0-1.11.1-1.51.01.5-1.3-1.0-0.7-0.00.3
Pavlov. Cond. lever latency0.20.31.3-0.1-0.00.3-0.3-0.30.3-0.4-0.40.4-0.4-0.20.5-0.5-0.3-0.3-0.0-0.40.4-0.50.80.5-0.9-0.10.40.91.1
Pavlov. Cond. magazine entry latency0.70.82.21.00.80.6-0.61.0-1.01.01.0-1.01.01.0-1.11.1-0.71.0-0.91.1-1.11.1-1.5-1.11.00.40.70.1-0.2
Pavlov. Cond. change in total contacts0.40.41.00.70.50.3-0.30.7-0.70.70.7-0.70.70.6-0.80.8-0.20.6-0.50.6-0.60.6-1.0-0.60.90.10.1-0.3-0.5
Pavlov. Cond. index score0.20.31.00.40.2-0.00.00.5-0.50.50.5-0.50.50.4-0.60.7-0.00.5-0.30.6-0.60.7-1.0-0.70.80.00.1-0.5-0.7
Pavlov. Cond. latency score0.30.41.30.30.2-0.10.10.5-0.50.60.5-0.50.50.4-0.70.70.10.6-0.20.7-0.70.8-1.1-0.81.00.1-0.1-0.9-1.1
Pavlov. Cond. lever contacts0.30.41.20.30.3-0.10.10.5-0.50.60.6-0.60.60.4-0.70.80.00.6-0.20.7-0.70.7-1.1-0.71.00.2-0.0-0.7-0.9
Pavlov. Cond. magazine entry number0.30.30.9-0.8-0.6-0.60.6-0.50.5-0.5-0.50.5-0.5-0.70.5-0.50.6-0.60.7-0.50.5-0.51.00.5-0.30.2-0.7-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.20.30.90.50.50.6-0.60.4-0.40.30.4-0.40.40.5-0.40.4-0.60.5-0.60.5-0.50.4-0.3-0.40.21.00.60.60.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.80.30.2-0.10.10.3-0.30.40.3-0.30.30.3-0.50.5-0.00.4-0.20.5-0.50.5-0.9-0.50.6-0.10.1-0.3-0.5
Pavlov. Cond. response bias0.40.51.30.90.80.6-0.60.8-0.80.70.8-0.80.80.8-0.80.8-0.60.7-0.80.7-0.70.6-1.1-0.60.60.10.70.50.3
Pavlov. Cond. lever latency2.83.85.4-2.3-2.2-2.32.3-2.02.0-1.9-1.91.9-1.9-2.21.9-1.92.3-2.02.2-1.91.9-1.81.51.8-1.3-1.3-2.1-1.7-1.3
Pavlov. Cond. magazine entry latency0.10.10.30.20.30.1-0.10.4-0.40.50.4-0.40.40.2-0.40.40.00.2-0.10.1-0.10.2-0.5-0.20.60.0-0.2-0.4-0.5
Pavlov. Cond. change in total contacts1.11.82.91.61.51.6-1.61.3-1.31.21.2-1.21.21.5-1.21.2-1.71.4-1.61.3-1.31.2-1.0-1.20.61.11.71.41.2
Pavlov. Cond. index score1.62.13.01.71.71.7-1.71.5-1.51.51.5-1.51.51.6-1.41.4-1.71.5-1.71.3-1.31.3-1.3-1.30.90.91.61.31.0
Pavlov. Cond. latency score1.31.72.21.51.51.5-1.51.4-1.41.41.4-1.41.41.4-1.31.3-1.51.3-1.41.2-1.21.2-1.2-1.20.90.91.31.00.7
Pavlov. Cond. lever contacts2.63.65.12.22.12.2-2.22.0-2.01.92.0-2.02.02.1-1.91.9-2.22.0-2.11.8-1.81.8-1.5-1.81.41.32.01.51.0
Pavlov. Cond. magazine entry number0.40.50.8-0.9-0.9-0.80.8-0.80.8-0.8-0.80.8-0.8-0.80.7-0.70.8-0.70.8-0.50.5-0.50.90.5-0.4-0.3-0.7-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.00.10.40.10.10.0-0.10.1-0.10.20.2-0.20.2-0.0-0.10.10.3-0.10.1-0.30.3-0.20.20.20.4-0.3-0.7-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.1.21.52.21.51.41.4-1.41.3-1.31.21.2-1.21.21.4-1.21.2-1.51.3-1.41.2-1.21.1-1.1-1.10.80.81.41.20.9
Pavlov. Cond. response bias2.73.65.22.32.22.2-2.22.0-2.02.02.0-2.02.02.1-1.91.9-2.22.0-2.21.8-1.81.7-1.6-1.71.41.22.01.51.1
Time in closed arm before self-admin1.21.52.4-1.2-1.1-1.11.1-1.11.1-1.2-1.11.1-1.1-1.31.4-1.41.2-1.41.2-1.51.5-1.51.31.5-1.3-1.6-1.1-0.20.2
Time in closed arm after self-admin2.93.15.5-1.8-1.6-1.51.5-1.61.6-1.9-1.61.7-1.7-1.82.1-2.11.6-2.01.6-2.12.1-2.12.02.1-2.0-2.3-1.3-0.10.5
Time in open arm before self-admin0.10.10.40.20.00.2-0.2-0.20.2-0.1-0.20.2-0.2-0.00.2-0.3-0.2-0.2-0.1-0.10.1-0.30.30.3-0.4-0.10.30.50.6
Time in open arm after self-admin2.02.23.81.41.31.2-1.21.4-1.41.61.4-1.51.51.5-1.81.8-1.21.7-1.31.7-1.71.8-1.8-1.81.91.90.9-0.2-0.7
Bone: periosteal estimation2.34.97.12.42.62.7-2.72.5-2.52.52.5-2.52.52.4-2.32.3-2.42.2-2.41.9-1.91.8-2.0-1.81.91.61.81.40.9
Bone: periosteal perimeter3.15.36.52.42.42.4-2.42.5-2.52.62.4-2.42.42.5-2.62.6-2.32.5-2.42.4-2.42.4-2.4-2.42.32.21.80.90.2
Bone: post-yield work0.50.71.8-1.0-0.8-1.01.0-0.50.5-0.7-0.50.5-0.5-0.90.6-0.61.2-0.91.1-0.90.9-0.80.70.8-0.1-0.7-1.3-1.2-1.0
Progressive ratio test 1 active lever presses2.22.74.12.01.81.9-1.91.5-1.51.71.5-1.51.51.8-1.61.6-2.01.7-1.91.6-1.61.5-1.6-1.51.11.61.71.51.1
Progressive ratio test 1 breakpoint2.42.94.42.11.92.0-2.01.6-1.61.71.5-1.61.61.9-1.71.6-2.01.8-2.01.7-1.71.6-1.7-1.61.11.71.81.51.2
Progressive ratio test 1 inactive lever presses1.11.62.51.41.21.2-1.21.3-1.31.31.3-1.21.21.3-1.41.4-1.31.4-1.31.6-1.61.5-1.4-1.51.21.31.20.40.0
Progressive ratio test 2 active lever presses0.80.91.31.11.00.9-0.91.0-1.01.01.0-0.90.91.0-1.01.0-1.01.0-1.01.1-1.11.0-1.1-1.00.91.00.80.40.2
Progressive ratio test 2 breakpoint0.91.11.51.21.01.0-1.01.1-1.11.11.1-0.90.91.1-1.11.1-1.11.1-1.11.1-1.11.1-1.1-1.10.91.10.80.50.2
Progressive ratio test 2 inactive lever presses2.43.95.42.12.11.9-1.92.1-2.12.32.1-2.12.12.1-2.32.3-1.82.1-1.82.2-2.22.1-2.3-2.12.21.81.40.3-0.3
Incentive Sensitization - Responses0.00.00.10.0-0.00.0-0.10.0-0.0-0.10.00.1-0.10.00.0-0.0-0.20.1-0.10.3-0.30.2-0.0-0.2-0.20.00.30.20.1
Incentive Sensitization - Breakpoint0.00.00.0-0.1-0.2-0.10.1-0.10.1-0.2-0.10.2-0.2-0.10.1-0.1-0.0-0.10.10.2-0.20.10.1-0.1-0.2-0.10.1-0.0-0.0
Sum of active levers in priming session hrs 5-60.80.71.40.60.80.7-0.70.8-0.91.10.9-0.90.90.8-1.01.1-0.60.9-0.70.8-0.81.0-0.9-1.01.21.20.3-0.2-0.5
Progressive ratio5.07.810.9-3.1-3.1-3.33.2-2.92.9-2.7-2.92.8-2.8-3.12.6-2.63.3-2.93.2-2.62.6-2.62.42.6-1.8-2.5-2.9-2.4-1.8
Food seeking constrained by brief footshock1.01.23.00.40.70.5-0.50.9-0.91.00.9-1.01.00.8-1.31.3-0.41.1-0.51.2-1.21.4-1.2-1.41.71.60.0-1.1-1.5
Seeking ratio, punishment vs. effort5.47.89.42.93.02.9-2.93.0-2.92.72.9-2.92.93.0-2.92.9-3.03.0-2.92.9-2.92.9-2.8-2.92.43.12.51.50.7
Retroperitoneal fat weight0.20.92.9-0.6-0.7-0.90.9-0.50.5-0.4-0.40.5-0.5-0.90.7-0.61.3-1.11.1-1.31.3-1.30.91.3-0.0-0.6-1.7-1.2-1.0
Reaction time number correct0.10.30.70.20.40.3-0.30.6-0.60.50.6-0.60.60.4-0.60.6-0.20.5-0.30.4-0.40.6-0.4-0.60.80.6-0.0-0.5-0.6
Reaction time mean minus median0.41.01.9-1.1-1.2-1.31.3-0.90.9-0.8-0.90.8-0.8-1.00.8-0.71.4-0.91.2-0.90.9-0.80.60.8-0.3-0.8-1.3-1.2-1.0
Reaction time mean minus median AUC0.10.30.9-0.5-0.7-0.80.8-0.50.5-0.4-0.40.4-0.4-0.50.2-0.20.8-0.40.6-0.40.4-0.2-0.00.20.1-0.1-0.8-0.9-0.9
Reaction time num false alarms3.34.76.02.12.22.1-2.12.4-2.42.22.4-2.42.42.3-2.42.4-2.02.4-2.12.3-2.32.4-2.0-2.42.22.11.70.6-0.1
Reaction time num false alarms AUC2.33.64.41.91.91.9-1.92.1-2.11.72.0-2.12.12.0-2.02.0-1.92.1-1.92.1-2.12.1-1.6-2.11.71.91.80.80.3
Reaction time trials correct on left0.10.30.70.20.40.3-0.30.6-0.60.50.6-0.60.60.4-0.60.6-0.20.5-0.30.4-0.40.6-0.4-0.60.80.6-0.0-0.5-0.6
Reaction time trials on left0.20.30.80.30.40.4-0.40.7-0.70.50.7-0.60.60.5-0.70.7-0.20.6-0.30.5-0.50.7-0.5-0.70.90.70.1-0.4-0.6
Reaction time mean0.00.00.10.30.10.1-0.10.1-0.10.10.1-0.10.10.1-0.10.1-0.10.1-0.20.1-0.10.0-0.2-0.00.00.00.10.20.2
Reaction time mean AUC0.00.00.00.20.00.1-0.10.1-0.10.10.1-0.10.10.1-0.10.1-0.10.1-0.10.1-0.10.0-0.2-0.00.00.00.10.20.2
Median of all reaction times0.10.20.30.60.40.5-0.50.4-0.40.40.4-0.40.40.5-0.40.4-0.50.4-0.50.4-0.40.3-0.4-0.30.20.20.50.50.4
Reaction time omissions1.21.74.21.30.91.0-1.01.0-1.01.11.0-1.11.11.4-1.41.4-1.31.6-1.31.8-1.81.8-1.4-1.81.12.01.40.4-0.0
Reaction time false alarm rate1.62.33.11.51.51.5-1.51.6-1.61.41.5-1.61.61.6-1.51.5-1.61.7-1.61.8-1.81.7-1.3-1.71.21.41.60.80.4
Reaction time premature initiation rate0.10.10.60.40.40.7-0.70.3-0.20.20.2-0.30.30.20.0-0.0-0.5-0.0-0.3-0.30.3-0.30.00.2-0.2-0.40.20.70.8
Reaction time premature initiations0.00.10.30.30.30.5-0.50.3-0.30.30.3-0.30.30.2-0.10.1-0.30.0-0.2-0.20.2-0.10.00.10.2-0.2-0.00.20.2
Std. dev. reaction times0.00.10.20.40.20.2-0.20.2-0.20.20.2-0.20.20.3-0.20.2-0.30.3-0.30.2-0.20.1-0.4-0.10.10.40.30.40.4
Reaction time trials completed0.20.30.80.30.40.4-0.40.7-0.70.50.7-0.60.60.5-0.70.7-0.20.6-0.30.5-0.50.7-0.5-0.70.90.70.1-0.4-0.6
Reaction time trials AUC0.10.30.70.30.40.3-0.30.6-0.60.50.6-0.60.60.4-0.70.7-0.20.5-0.30.5-0.50.6-0.4-0.60.80.70.0-0.4-0.6
Run reversals in cocaine runway, females0.70.71.31.11.00.9-0.91.0-1.01.11.0-1.11.10.9-1.01.0-0.60.8-0.80.5-0.50.6-0.9-0.61.00.40.30.1-0.1
Run reversals in cocaine runway, males2.12.13.51.51.21.5-1.51.2-1.21.31.2-1.21.21.5-1.41.4-1.71.6-1.61.9-1.91.7-1.6-1.71.01.61.70.90.5
Latency to leave start box in cocaine runway0.91.11.8-1.2-1.3-1.21.2-1.01.0-1.4-1.01.1-1.1-1.21.1-1.11.0-1.11.2-0.80.8-0.91.00.9-1.0-0.8-0.8-0.7-0.5
Latency to leave start box in cocaine runway, F3.13.66.2-2.2-2.3-2.02.0-2.02.0-2.5-2.12.2-2.2-2.12.2-2.21.6-1.91.9-1.61.6-1.61.71.6-2.2-1.8-1.1-0.5-0.0
Latency to leave start box in cocaine runway, M0.40.40.80.80.70.7-0.70.7-0.70.80.7-0.70.70.6-0.70.7-0.50.6-0.50.5-0.50.5-0.3-0.50.90.70.1-0.2-0.3
Std. dev. time between licks in bursts0.60.91.51.11.21.2-1.21.1-1.11.01.1-1.11.11.0-0.90.9-1.00.9-1.00.7-0.70.6-0.6-0.60.70.60.70.80.6
Total sessions with >9 infusions0.10.10.40.50.30.4-0.4-0.10.10.3-0.1-0.00.00.3-0.10.1-0.40.2-0.40.3-0.30.1-0.2-0.1-0.10.10.50.60.6
Short access day 1 total inactive lever presses0.20.31.00.60.50.2-0.20.6-0.60.70.7-0.70.70.4-0.70.7-0.10.4-0.20.4-0.40.3-0.8-0.31.0-0.0-0.1-0.6-0.7
Short access day 10 total inactive lever presses0.10.21.1-0.5-0.3-0.50.5-0.10.1-0.2-0.10.1-0.1-0.50.2-0.20.7-0.50.7-0.40.4-0.40.20.40.3-0.7-0.9-1.0-1.0
Short access day 1 total infusions0.20.30.60.50.50.4-0.40.5-0.50.60.5-0.60.60.4-0.60.6-0.30.5-0.30.6-0.60.5-0.6-0.50.80.40.1-0.3-0.5
Short access day 10 total infusions0.00.00.10.30.10.1-0.1-0.00.00.1-0.00.1-0.10.00.1-0.1-0.1-0.1-0.1-0.20.2-0.20.00.2-0.1-0.30.00.30.3
Short access total infusions0.10.20.60.80.50.5-0.50.4-0.40.60.4-0.40.40.5-0.40.4-0.50.4-0.50.3-0.30.3-0.5-0.20.40.20.30.40.3
Short access day 1 locomotion0.20.20.80.30.30.1-0.10.5-0.50.60.5-0.50.50.3-0.60.60.00.3-0.10.3-0.30.4-0.6-0.40.90.1-0.3-0.6-0.8
Short access day 10 total locomotion0.51.01.61.11.00.8-0.81.0-1.01.31.0-0.90.91.0-1.11.1-0.91.0-0.91.1-1.11.1-1.2-1.11.10.80.80.2-0.1
Short access total locomotion0.81.01.61.11.00.8-0.81.0-1.01.31.0-1.01.01.0-1.21.2-0.81.0-0.91.1-1.11.0-1.2-1.01.20.80.60.1-0.2
One hour access (0.3 mA shock)0.30.40.70.90.50.6-0.60.5-0.50.50.5-0.40.40.6-0.60.6-0.70.7-0.70.8-0.80.7-0.7-0.70.40.60.70.50.3
Compulsive drug intake0.10.10.2-0.4-0.4-0.30.3-0.30.3-0.4-0.20.4-0.4-0.40.3-0.30.4-0.30.5-0.30.3-0.40.30.4-0.1-0.3-0.5-0.5-0.4
One hour access (shock baseline)0.10.20.40.50.40.4-0.40.3-0.30.30.3-0.20.20.5-0.30.3-0.60.4-0.50.5-0.50.4-0.5-0.40.10.40.60.60.5
Social response proportion0.80.91.90.70.80.7-0.70.9-0.91.00.9-0.90.90.9-1.11.1-0.81.0-0.81.2-1.21.2-1.0-1.21.11.40.6-0.1-0.5
Social responses2.02.54.51.31.61.6-1.61.4-1.41.31.4-1.31.31.7-1.41.4-2.01.8-1.81.9-1.91.9-1.5-1.90.82.12.01.40.9
Social time0.20.31.00.30.20.4-0.40.2-0.20.20.2-0.20.20.5-0.40.4-0.70.6-0.50.9-0.90.9-0.4-0.90.1-0.11.00.50.3
Soleus weight0.41.12.31.11.31.1-1.11.4-1.41.41.4-1.41.41.1-1.31.3-0.71.0-0.90.7-0.70.7-0.9-0.71.50.20.1-0.2-0.4
Bone: stiffness1.83.03.91.71.71.8-1.81.8-1.81.71.8-1.81.81.8-1.81.8-1.81.9-1.72.0-2.01.9-1.8-1.91.51.71.60.70.2
Tibialis anterior weight1.24.06.32.42.42.5-2.52.1-2.12.02.1-2.12.12.3-1.91.9-2.42.0-2.41.7-1.71.5-1.8-1.51.21.02.22.01.6
Time to tail flick, vehicle, before self-admin0.40.41.8-0.2-0.2-0.50.50.1-0.1-0.10.1-0.10.1-0.40.0-0.00.9-0.50.7-0.60.6-0.50.30.50.6-0.8-1.2-1.3-1.3
Time to tail flick, vehicle, after self-admin1.11.42.7-1.2-0.9-0.90.9-1.01.0-0.9-1.01.2-1.2-1.21.2-1.21.1-1.41.1-1.61.6-1.61.31.6-1.0-1.5-1.2-0.30.1
Time to tail flick, test, before self-admin0.40.42.00.70.50.7-0.70.1-0.10.30.0-0.10.10.5-0.10.1-0.90.3-0.70.5-0.50.2-0.3-0.2-0.50.41.21.41.4
Time to tail flick, test, after self-admin0.20.21.1-0.6-0.5-0.70.7-0.20.2-0.3-0.20.2-0.2-0.40.1-0.10.6-0.20.6-0.10.10.10.2-0.10.30.2-0.6-1.0-1.1
Delta time to tail flick, vehicle, before/after SA0.50.51.90.50.71.0-1.00.5-0.50.60.4-0.40.40.7-0.30.3-1.10.6-0.90.5-0.50.5-0.4-0.5-0.20.71.11.41.3
Delta time to tail flick, test, before/after SA0.40.43.1-0.6-0.3-0.70.70.1-0.1-0.10.2-0.10.1-0.4-0.20.20.9-0.20.7-0.30.3-0.00.20.00.90.0-1.2-1.7-1.8
Tibia length1.84.915.92.32.43.0-3.01.7-1.61.51.5-1.51.52.2-1.21.1-3.31.8-2.81.5-1.51.2-1.2-1.2-0.31.23.44.03.8
Ambulatory time before self-admin2.74.15.82.42.22.4-2.42.0-2.02.12.0-2.02.02.2-2.12.1-2.32.1-2.22.0-2.02.0-1.7-2.01.71.81.91.30.8
Ambulatory time after self-admin0.50.62.00.91.01.1-1.10.5-0.50.70.5-0.60.60.9-0.50.5-1.10.6-1.00.4-0.40.3-0.5-0.3-0.00.50.91.41.4
Bone: tissue strength0.40.40.90.60.60.4-0.40.7-0.70.80.8-0.80.80.6-0.80.8-0.30.7-0.50.6-0.60.7-0.9-0.71.00.80.1-0.3-0.5
Total heroin consumption1.92.34.41.11.21.3-1.31.1-1.11.51.2-1.21.21.5-1.61.6-1.61.8-1.52.1-2.12.0-1.5-2.01.32.11.60.4-0.1
Bone: trabecular number3.25.37.52.52.62.5-2.52.6-2.62.72.6-2.62.62.5-2.52.5-2.32.4-2.42.1-2.12.1-2.3-2.12.22.21.71.10.6
Bone: trabecular spacing0.50.71.3-0.8-1.0-1.01.0-1.01.0-1.0-1.01.0-1.0-0.90.8-0.80.8-0.70.8-0.50.5-0.50.70.5-0.8-1.1-0.5-0.5-0.3
Bone: trabecular thickness1.31.64.41.21.21.2-1.21.2-1.21.41.2-1.21.21.3-1.31.3-1.21.4-1.21.4-1.41.4-1.4-1.41.12.11.10.50.1
Bone: trabecular tissue density1.52.23.91.51.41.2-1.21.3-1.31.51.3-1.31.31.6-1.61.6-1.51.8-1.61.9-1.91.9-2.0-1.91.31.51.60.70.2
Water consumed over 24 hours0.10.10.30.0-0.0-0.10.1-0.20.2-0.0-0.20.2-0.2-0.10.2-0.20.2-0.30.1-0.50.5-0.40.10.4-0.3-0.3-0.30.30.4
Number of responses in last shaping day0.20.20.40.60.60.5-0.50.7-0.70.60.7-0.60.60.5-0.50.5-0.50.4-0.50.4-0.40.3-0.4-0.30.50.10.30.30.2