Ttc4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ttc4 0.04 0.03 8.6e-04 0 0.01 0.01 0.01 1.5e-01 9.1e-03 4.1e-02 3.7e-02
2 pVTA gene expression Ttc4 0.1 0.05 2.5e-06 0.06 0.06 0.07 0.06 3.2e-05 2.1e-05 4.4e-06 2.5e-05
3 Brain isoform ratio XM_039110294.2 0.07 0.04 3.5e-07 0.08 0.08 0.08 0.08 6.3e-08 4.2e-08 3.6e-08 5.4e-08
4 Brain isoform ratio NM_001395043.1 0.07 0.04 6.3e-07 0.08 0.08 0.08 0.08 1.1e-07 7.9e-08 7.3e-08 1.1e-07
5 Brain alternative TSS NM_001395043.1 0.1 0.05 2.0e-11 0.11 0.13 0.11 0.12 1.1e-10 9.4e-12 1.4e-10 7.3e-11
6 Brain alternative TSS XM_039110294.2 0.1 0.05 1.9e-11 0.12 0.13 0.11 0.12 6.9e-11 8.0e-12 1.1e-10 4.6e-11
7 Liver gene expression Ttc4 0.08 0.04 1.4e-07 0.04 0.03 0.02 0.03 1.3e-05 2.4e-04 6.1e-03 7.6e-04
8 OFC gene expression Ttc4 0.29 0.14 2.7e-04 0.17 0.09 0.14 0.14 6.4e-05 4.1e-03 3.0e-04 3.3e-04
9 NAcc isoform ratio NM_001395043.1 0.03 0.01 3.5e-04 0.02 0.02 0.02 0.02 1.7e-04 2.4e-04 2.7e-04 4.4e-04
10 NAcc isoform ratio XM_039110294.2 0.02 0.01 7.6e-04 0.02 0.02 0.02 0.02 2.6e-04 5.1e-04 3.8e-04 3.8e-04
11 Brain gene expression Ttc4 0.05 0.03 1.5e-05 0.06 0.04 0.03 0.05 4.7e-06 8.6e-05 4.7e-04 1.5e-05
12 IC alternative TSS NM_001395043.1 0.07 0.05 7.3e-03 0.07 0.05 0.04 0.05 5.5e-04 4.9e-03 9.0e-03 3.1e-03
13 IC alternative TSS XM_039110294.2 0.07 0.05 8.2e-03 0.07 0.05 0.04 0.05 5.5e-04 5.2e-03 7.6e-03 2.7e-03
14 NAcc alternative TSS NM_001395043.1 0.06 0.03 6.1e-10 0.06 0.07 0.06 0.07 7.7e-10 1.2e-10 4.8e-10 1.9e-10
15 Eye alternative TSS XM_039110294.2 0.32 0.2 7.7e-03 0.24 0.04 0.17 0.18 1.3e-04 9.4e-02 1.4e-03 1.0e-03
16 IC gene expression Ttc4 0.1 0.07 4.0e-03 0.06 0.03 0.04 0.05 2.5e-03 1.7e-02 9.1e-03 4.6e-03
17 NAcc gene expression Ttc4 0.16 0.08 0.0e+00 0.16 0.17 0.16 0.17 2.0e-23 1.1e-24 6.5e-23 6.6e-25
18 NAcc alternative TSS XM_039110294.2 0.06 0.03 6.1e-10 0.06 0.07 0.07 0.07 4.0e-10 1.3e-10 1.2e-10 1.1e-10
19 PL gene expression Ttc4 0.03 0.02 3.0e-03 0.02 0.02 0.02 0.02 2.7e-03 3.4e-03 2.5e-03 2.0e-03
20 PL alternative TSS XM_039110294.2 0.04 0.02 1.1e-04 0.03 0.03 0.03 0.03 4.5e-04 2.5e-04 7.6e-04 3.5e-04
21 PL alternative TSS NM_001395043.1 0.04 0.02 1.0e-04 0.03 0.03 0.03 0.03 4.0e-04 2.6e-04 5.6e-04 2.8e-04
22 PL isoform ratio NM_001395043.1 0.03 0.02 2.9e-03 0 0.02 0.01 0.01 3.6e-01 2.9e-03 1.8e-02 6.2e-02
23 PL isoform ratio XM_039110294.2 0.03 0.02 1.8e-03 0 0.02 0.01 0.01 3.1e-01 2.0e-03 1.3e-02 4.1e-02
24 pVTA alternative TSS XM_039110294.2 0.09 0.05 7.8e-06 0.04 0.05 0.06 0.04 4.0e-04 3.4e-05 1.9e-05 1.5e-04
25 pVTA alternative TSS NM_001395043.1 0.1 0.06 3.6e-06 0.04 0.06 0.07 0.05 2.9e-04 1.5e-05 2.8e-06 4.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.91.53.9-0.20.3-0.40.40.4-0.40.50.80.5-0.50.81.8-1.80.5-2.02.01.0-0.81.0-1.11.11.9-1.9-2.01.9
Area under the delay curve0.10.10.60.10.4-0.40.40.2-0.20.30.30.2-0.20.30.8-0.8-0.2-0.60.60.3-0.10.3-0.10.1-0.00.10.2-0.2
BMI with tail0.62.25.0-2.2-1.41.8-1.8-1.91.9-1.8-1.6-1.81.8-1.6-0.70.7-2.00.6-0.6-1.31.6-1.41.6-1.6-0.80.70.7-0.8
BMI without tail0.31.02.4-1.5-1.21.4-1.4-1.41.4-1.3-1.1-1.11.1-1.1-0.40.4-1.20.4-0.4-0.81.0-0.91.1-1.1-0.50.40.0-0.1
Body weight0.41.74.5-2.1-1.61.6-1.6-1.71.7-1.6-1.4-1.61.6-1.3-0.50.5-1.90.7-0.7-1.21.3-1.21.3-1.3-0.50.40.6-0.6
Weight adjusted by age0.40.61.7-0.6-0.30.9-0.9-0.80.8-0.7-0.7-0.70.7-0.7-1.31.3-0.51.2-1.2-0.90.6-0.80.7-0.7-0.70.60.4-0.4
Bone surface0.20.41.8-0.01.3-0.30.30.2-0.20.00.40.2-0.20.40.9-0.90.2-1.31.30.4-0.30.5-0.40.40.6-0.7-0.70.7
Bone volume0.20.30.8-0.90.30.3-0.3-0.40.4-0.4-0.2-0.40.4-0.10.7-0.7-0.5-0.90.9-0.10.20.0-0.0-0.00.7-0.7-0.70.6
Breakpoint value in progressive ratio session0.40.52.0-0.5-1.2-0.50.50.3-0.30.30.30.4-0.40.20.8-0.8-0.0-0.80.80.3-0.10.3-0.70.71.4-1.4-0.70.7
Number of licking bursts0.50.82.0-0.6-1.20.6-0.6-0.70.7-0.6-0.7-0.70.7-0.8-0.90.9-0.91.2-1.2-0.90.8-0.80.9-0.9-0.91.01.4-1.4
Context. condit. distance diff. score0.60.82.9-0.3-0.3-0.20.20.2-0.20.60.50.6-0.60.50.9-0.90.5-0.90.90.7-0.70.9-0.80.81.6-1.6-1.71.7
Locomotion velocity, session 12.02.23.31.20.8-1.31.31.4-1.41.41.61.3-1.31.61.8-1.81.2-1.61.61.7-1.71.7-1.41.41.3-1.3-1.71.7
Locomotion distance, session 10.10.10.5-0.40.30.0-0.0-0.10.10.20.10.0-0.00.1-0.00.0-0.20.3-0.30.3-0.20.3-0.10.10.4-0.4-0.70.6
Locomotion velocity, session 21.01.22.21.10.3-1.01.01.1-1.11.01.00.9-0.91.01.5-1.51.1-1.31.31.2-1.00.9-1.11.10.9-0.8-1.21.2
Locomotion distance, session 20.50.81.4-1.0-0.31.1-1.1-1.01.0-0.9-0.9-1.21.2-0.9-0.40.4-1.10.8-0.8-0.80.8-0.81.0-1.0-0.80.80.3-0.3
Locomotion velocity, session 30.60.72.0-0.31.0-0.20.20.1-0.10.30.60.1-0.10.61.4-1.4-0.1-1.41.40.6-0.70.8-0.40.40.9-0.9-1.21.2
Locomotion distance, session 30.10.10.3-0.50.50.3-0.3-0.30.3-0.1-0.0-0.10.1-0.00.2-0.2-0.20.0-0.0-0.1-0.10.20.1-0.10.3-0.3-0.50.5
Stereotopy head waving bouts, day 30.10.10.7-0.5-0.80.1-0.1-0.20.3-0.4-0.1-0.50.5-0.00.0-0.0-0.6-0.10.1-0.20.1-0.10.3-0.3-0.10.10.4-0.4
Stereotopy head waving duration, day 30.10.10.5-0.2-0.7-0.10.1-0.00.1-0.3-0.1-0.40.4-0.10.3-0.3-0.3-0.50.5-0.10.1-0.20.1-0.10.00.00.3-0.3
Locomotion velocity, session 70.10.20.5-0.6-0.10.7-0.7-0.60.6-0.4-0.3-0.30.3-0.20.5-0.5-0.4-0.20.2-0.3-0.00.10.4-0.4-0.10.0-0.40.4
Locomotion distance, session 70.20.31.6-0.4-0.10.7-0.7-0.40.40.20.2-0.00.00.20.6-0.60.1-0.50.50.3-0.30.40.0-0.10.4-0.5-1.31.3
Stereotopy head waving bouts, day 71.31.42.61.01.6-1.51.51.3-1.21.01.41.0-1.01.41.3-1.30.7-1.51.51.2-1.51.5-1.01.00.8-0.7-0.50.5
Stereotopy head waving duration, day 71.11.43.21.01.8-1.41.41.2-1.20.91.30.9-0.91.31.4-1.40.7-1.51.51.1-1.41.4-1.01.00.7-0.7-0.50.5
Locomotion velocity, session 82.02.45.90.90.5-1.11.11.1-1.11.21.31.1-1.11.62.4-2.41.0-2.32.31.6-1.61.7-1.21.21.4-1.4-1.81.8
Locomotion distance, session 80.40.52.6-1.2-0.60.6-0.6-0.60.6-0.1-0.0-0.20.20.10.8-0.8-0.4-0.60.60.2-0.30.6-0.10.11.1-1.2-1.61.5
Degree of sensitization distance0.20.21.4-0.5-1.20.8-0.8-0.60.6-0.1-0.4-0.30.3-0.3-0.20.2-0.2-0.00.0-0.20.3-0.30.4-0.4-0.20.1-0.20.2
Degree of sensitization stereotypy0.60.72.60.81.6-1.11.10.9-0.90.60.90.7-0.70.90.8-0.80.5-0.90.90.8-1.01.0-0.60.60.4-0.3-0.10.1
Conditioned locomotion0.10.10.6-0.5-0.80.3-0.4-0.30.3-0.1-0.3-0.30.3-0.20.5-0.5-0.4-0.70.70.00.1-0.20.2-0.20.0-0.1-0.20.2
Cocaine response after cond. corrected1.41.73.7-1.5-1.91.4-1.4-1.41.4-1.4-1.5-1.41.4-1.6-1.31.3-1.21.3-1.3-1.51.5-1.51.1-1.1-0.50.50.6-0.7
Cocaine response after cond. not corrected2.22.53.8-1.6-1.61.6-1.6-1.61.6-1.6-1.7-1.51.5-1.9-1.91.9-1.31.9-1.9-1.81.8-1.91.4-1.4-1.00.91.1-1.1
Cocaine response before conditioning0.30.31.40.41.20.3-0.3-0.20.2-0.2-0.2-0.10.1-0.2-0.80.80.10.7-0.7-0.30.3-0.30.5-0.5-1.01.00.8-0.7
Saline control response0.30.40.90.3-0.2-0.50.50.5-0.50.90.70.8-0.80.70.3-0.30.6-0.10.10.8-0.80.8-0.70.70.8-0.8-0.90.9
Bone: connectivity density1.52.44.90.51.8-1.01.01.0-1.00.91.41.0-1.01.42.1-2.11.0-2.22.21.4-1.31.5-1.41.41.9-1.9-2.01.9
Bone: cortical apparent density2.53.44.91.4-0.2-1.61.61.7-1.81.81.61.8-1.81.72.0-2.01.8-2.12.12.0-1.81.7-2.02.02.1-2.1-2.22.2
Bone: cortical area0.81.32.9-1.7-0.61.4-1.4-1.51.5-1.4-1.1-1.51.5-1.1-0.80.8-1.40.5-0.5-1.11.3-1.11.1-1.1-0.50.40.3-0.3
Bone: cortical porosity0.30.41.7-0.4-1.3-0.60.60.1-0.10.1-0.10.2-0.2-0.1-0.90.9-0.51.1-1.1-0.30.3-0.2-0.10.10.2-0.20.8-0.9
Bone: cortical porosity0.40.41.50.1-1.0-1.21.20.6-0.60.40.20.6-0.60.2-0.50.5-0.20.8-0.8-0.00.00.0-0.40.40.3-0.21.0-1.0
Bone: cortical thickness2.13.67.4-2.7-2.02.3-2.4-2.42.4-2.3-1.9-2.42.4-1.9-1.21.2-2.40.9-0.9-1.82.0-1.81.9-1.9-1.00.90.6-0.7
Bone: cortical thickness1.11.23.8-2.0-1.41.4-1.4-1.51.5-1.2-0.8-1.31.3-1.0-0.90.9-1.50.8-0.8-1.01.1-1.01.1-1.1-0.20.10.2-0.2
Bone: cortical tissue density2.73.75.11.5-0.1-1.71.71.9-1.91.91.71.9-1.91.82.0-2.01.9-2.22.22.1-1.91.8-2.12.12.1-2.1-2.32.2
Condit. Reinf. active minus inactive responses0.20.20.7-0.30.70.8-0.8-0.60.6-0.4-0.1-0.50.5-0.00.1-0.1-0.20.0-0.0-0.30.1-0.00.5-0.6-0.50.5-0.20.2
Condit. Reinf. active-inactive response ratio0.40.41.1-0.60.61.1-1.1-0.80.8-0.8-0.5-0.90.9-0.40.3-0.3-0.4-0.30.3-0.70.4-0.40.8-0.8-0.60.6-0.10.1
Condit. Reinf. active responses0.60.71.9-0.4-0.10.8-0.8-0.80.8-0.6-0.4-0.70.7-0.4-1.01.0-0.71.1-1.1-0.70.4-0.51.1-1.1-1.41.40.9-0.9
Condit. Reinf. inactive responses0.40.51.80.2-0.9-0.30.30.0-0.00.20.10.2-0.20.1-1.21.2-0.21.4-1.40.00.0-0.10.4-0.3-0.80.91.1-1.0
Incentive salience index mean0.80.91.8-0.90.41.4-1.4-1.21.2-1.1-0.7-1.21.2-0.6-0.80.8-0.90.9-0.9-1.00.6-0.61.2-1.2-1.11.10.6-0.5
Condit. Reinf. lever presses0.81.11.9-0.90.61.3-1.3-1.31.3-1.3-0.7-1.21.2-0.6-1.01.0-1.00.9-0.9-1.10.6-0.61.3-1.4-1.31.30.8-0.8
Condit. Reinf. active minus inactive responses0.20.21.0-0.40.51.0-1.0-0.70.7-0.5-0.2-0.70.7-0.1-0.40.4-0.10.0-0.0-0.30.2-0.10.5-0.6-0.40.3-0.40.4
Condit. Reinf. active-inactive response ratio0.30.31.40.21.00.5-0.5-0.00.00.30.50.2-0.20.70.5-0.50.6-0.70.70.4-0.60.7-0.20.10.3-0.3-1.11.2
Condit. Reinf. active responses0.40.51.5-0.80.41.2-1.2-1.01.0-0.8-0.5-1.01.0-0.5-0.70.7-0.50.4-0.4-0.60.6-0.50.8-0.8-0.50.4-0.10.2
Condit. Reinf. inactive responses1.21.62.5-1.2-0.61.2-1.2-1.21.2-1.3-1.2-1.31.3-1.3-1.61.6-1.21.4-1.4-1.31.5-1.31.2-1.2-0.90.91.0-1.0
Condit. Reinf. lever presses0.50.77.31.32.7-0.50.50.7-0.70.50.90.4-0.40.80.8-0.80.9-0.90.90.6-0.70.8-0.30.2-0.40.4-0.40.5
Condit. Reinf. lever reinforcers received0.40.51.2-0.61.11.1-1.1-0.80.8-0.8-0.5-1.01.0-0.4-0.60.6-0.40.4-0.4-0.60.5-0.40.8-0.8-0.70.70.0-0.0
Conditioned reinforcement - actives0.30.61.3-1.1-0.61.0-1.0-1.01.0-0.7-0.8-0.80.8-0.8-0.40.4-0.90.5-0.5-0.90.8-0.70.8-0.8-0.30.30.4-0.4
Conditioned reinforcement - inactives0.00.10.2-0.3-0.1-0.30.30.1-0.00.20.30.1-0.10.30.2-0.2-0.2-0.20.20.2-0.30.4-0.10.10.4-0.30.2-0.2
Conditioned locomotion0.30.31.4-0.3-0.10.1-0.1-0.10.10.70.60.5-0.50.60.5-0.50.3-0.60.60.5-0.70.7-0.30.30.8-0.9-1.11.2
Patch foraging indifference point 0 sec0.10.10.60.30.60.3-0.3-0.20.20.00.30.0-0.00.3-0.20.20.10.3-0.30.1-0.30.20.4-0.4-0.70.7-0.00.1
Patch foraging indifference point AUC0.10.20.7-0.0-0.20.2-0.20.1-0.10.00.00.1-0.10.00.6-0.60.4-0.70.70.1-0.10.1-0.40.30.6-0.7-0.80.8
Delay disc. indifference point, 0s delay0.30.30.70.10.1-0.60.60.4-0.40.80.80.5-0.50.80.6-0.60.1-0.60.60.8-0.60.8-0.40.50.5-0.5-0.20.2
Delay disc. indifference point, 16s delay0.91.01.9-1.2-0.60.9-0.9-1.11.1-1.0-0.9-1.01.0-0.9-0.90.9-1.40.9-0.9-0.91.0-0.91.1-1.1-0.90.91.0-1.1
Delay disc. indifference point, 2s delay0.20.21.00.21.0-0.30.30.2-0.30.40.20.3-0.30.20.8-0.80.1-0.70.70.3-0.10.4-0.30.30.3-0.3-0.20.2
Delay disc. indifference point, 24s delay0.20.31.50.60.6-0.30.30.3-0.30.20.1-0.00.00.11.2-1.20.0-0.90.90.20.10.00.1-0.1-0.50.60.3-0.3
Delay disc. indifference point, 4s delay0.20.21.0-0.00.2-0.50.50.3-0.30.30.40.2-0.20.41.0-1.0-0.2-0.80.80.5-0.50.7-0.30.30.4-0.4-0.10.0
Delay disc. indifference point, 8s delay0.00.10.20.10.0-0.10.1-0.00.0-0.0-0.0-0.10.1-0.10.3-0.3-0.2-0.20.2-0.00.3-0.10.2-0.2-0.40.40.4-0.4
Indifference point function ln k0.20.41.2-0.80.00.4-0.3-0.60.6-0.4-0.6-0.50.5-0.6-1.11.1-0.71.0-1.0-0.50.6-0.40.5-0.5-0.20.20.6-0.6
Indifference point function log k0.20.41.2-0.80.00.4-0.3-0.60.6-0.4-0.6-0.50.5-0.6-1.11.1-0.71.0-1.0-0.50.6-0.40.5-0.5-0.20.20.6-0.6
Patch foraging total patch changes 0 sec0.00.10.50.20.70.2-0.2-0.10.10.10.50.1-0.10.40.0-0.00.10.1-0.10.2-0.40.40.2-0.2-0.40.4-0.30.3
Patch foraging total patch changes 12 sec1.92.44.91.82.2-1.31.31.6-1.61.51.81.5-1.51.81.8-1.81.7-1.51.51.6-1.81.7-1.31.30.8-0.8-1.41.4
Patch foraging total patch changes 18 sec0.00.10.3-0.10.10.5-0.5-0.20.2-0.10.10.0-0.0-0.00.1-0.10.1-0.10.10.0-0.1-0.00.1-0.1-0.0-0.0-0.60.6
Patch foraging total patch changes 24 sec0.71.23.5-0.3-0.60.8-0.8-0.90.9-0.8-0.6-0.70.7-0.6-1.61.6-0.71.9-1.9-0.80.7-0.81.2-1.2-1.61.61.3-1.2
Patch foraging total patch changes 6 sec0.10.10.40.00.10.4-0.4-0.30.2-0.20.2-0.20.20.1-0.40.4-0.00.6-0.6-0.0-0.1-0.00.4-0.4-0.50.5-0.10.1
Patch foraging time to switch 0 sec1.12.24.62.21.1-2.02.01.9-1.91.61.61.7-1.71.61.3-1.31.6-1.21.21.4-1.51.4-1.41.40.5-0.4-0.40.4
Patch foraging water rate 0 sec1.32.64.1-2.0-1.22.0-2.0-2.01.9-1.8-1.6-1.91.9-1.6-1.41.4-1.81.4-1.4-1.61.6-1.61.7-1.7-1.11.00.9-0.9
Patch foraging water rate 12 sec2.14.36.5-2.5-0.92.5-2.5-2.52.5-2.5-2.1-2.42.4-2.1-1.71.7-2.41.5-1.5-2.12.0-2.02.3-2.3-1.71.61.4-1.4
Patch foraging water rate 18 sec0.10.10.5-0.10.7-0.30.30.00.00.10.40.1-0.10.50.7-0.7-0.3-0.60.60.3-0.40.50.1-0.1-0.00.10.1-0.2
Patch foraging water rate 24 sec0.10.20.8-0.9-0.90.2-0.2-0.40.5-0.3-0.2-0.30.3-0.2-0.60.6-0.70.5-0.5-0.30.2-0.10.2-0.20.2-0.30.2-0.2
Patch foraging water rate 6 sec1.31.92.7-1.1-0.41.2-1.2-1.41.4-1.5-1.3-1.51.5-1.2-1.41.4-1.51.3-1.3-1.31.2-1.31.6-1.6-1.61.61.7-1.7
Seeking ratio, delayed vs. immediate footshock2.42.96.1-2.4-2.52.2-2.2-2.12.1-1.8-1.8-1.81.8-2.0-1.31.3-1.71.2-1.2-1.81.8-1.81.5-1.5-0.50.40.4-0.4
Distance traveled before self-admin1.01.34.3-2.1-0.51.9-1.9-1.71.7-1.0-1.0-1.21.2-0.9-0.80.8-1.20.9-0.9-0.91.0-0.61.0-1.00.1-0.2-0.50.5
Distance traveled after self-admin1.41.83.7-1.8-1.21.9-1.9-1.91.9-1.3-1.4-1.51.5-1.3-0.60.6-1.50.7-0.7-1.11.1-1.11.6-1.6-1.00.90.2-0.2
Extensor digitorum longus weight0.93.610.1-3.2-2.22.4-2.4-2.32.3-1.9-2.1-1.91.9-2.1-1.91.9-2.12.0-2.0-2.02.0-1.61.3-1.30.3-0.40.1-0.1
Bone: elastic displacement0.70.95.0-0.8-2.21.4-1.4-1.00.9-0.5-1.0-0.60.6-1.0-0.70.7-0.00.9-0.9-0.71.1-1.00.4-0.50.0-0.1-0.90.9
Bone: elastic work0.60.83.2-1.2-1.81.3-1.3-1.01.0-0.6-0.8-0.70.7-0.8-0.90.9-0.40.8-0.8-0.60.8-0.70.4-0.40.3-0.4-0.80.8
Bone: endosteal estimation0.20.53.20.61.8-0.60.60.6-0.60.80.60.9-0.90.6-0.20.20.90.2-0.20.4-0.50.7-0.80.80.8-0.8-0.50.6
Bone: endosteal perimeter0.20.52.51.01.6-1.01.00.8-0.80.80.60.9-0.90.7-0.10.10.80.1-0.10.5-0.50.6-0.60.60.2-0.20.00.0
Epididymis fat weight0.10.30.80.80.5-0.90.90.8-0.80.70.70.7-0.70.70.2-0.20.4-0.10.10.6-0.60.6-0.50.50.1-0.00.4-0.4
Delta time in closed arm before/after self-admin0.70.63.5-0.6-0.70.5-0.5-0.10.0-0.00.00.2-0.2-0.0-0.20.20.5-0.10.1-0.1-0.00.1-0.80.81.7-1.9-1.81.8
Delta time in open arm before/after self-admin0.30.31.40.90.1-0.60.60.5-0.40.30.10.1-0.10.20.1-0.10.1-0.00.00.2-0.20.00.2-0.2-1.01.11.2-1.2
Diff in mean of infusions in LGA sessions0.30.31.3-1.1-1.10.1-0.1-0.40.4-0.5-0.5-0.10.1-0.7-0.50.5-0.70.4-0.4-0.80.7-0.5-0.10.10.8-0.90.3-0.3
Delay discount exponential model param0.20.20.8-0.2-0.60.5-0.5-0.30.3-0.3-0.4-0.20.2-0.3-0.90.90.10.7-0.7-0.40.2-0.40.1-0.1-0.00.0-0.10.2
Extinction: sum of active levers before priming0.20.21.7-0.80.0-0.10.1-0.00.10.10.30.2-0.20.3-0.00.0-0.20.1-0.1-0.2-0.00.5-0.50.51.3-1.3-0.60.6
Active lever presses in extinction session 61.21.24.1-2.0-1.91.2-1.2-1.41.4-1.2-1.2-1.31.3-1.2-0.20.2-1.60.4-0.4-0.91.0-0.90.9-0.90.0-0.10.3-0.3
Bone: final force0.10.10.5-0.00.7-0.20.20.2-0.20.10.30.2-0.20.1-0.10.10.2-0.10.10.3-0.00.2-0.40.40.5-0.5-0.50.5
Bone: final moment0.00.10.3-0.30.50.0-0.0-0.00.0-0.00.1-0.00.0-0.0-0.30.30.00.1-0.10.10.2-0.0-0.20.20.4-0.5-0.50.5
Food consumed during 24 hour testing period0.30.41.80.30.9-0.10.1-0.00.00.10.5-0.00.00.41.0-1.0-0.2-1.31.30.5-0.50.30.4-0.4-0.70.70.2-0.2
Glucose0.10.10.2-0.10.10.5-0.5-0.40.3-0.4-0.2-0.20.2-0.20.0-0.0-0.1-0.10.1-0.20.2-0.20.4-0.4-0.50.5-0.20.2
Heart weight0.50.81.8-1.3-0.41.1-1.1-1.11.1-1.2-1.1-1.11.1-1.1-0.30.3-1.20.3-0.3-1.01.0-0.90.9-0.9-0.40.40.4-0.4
Delay discount hyperbolic model param0.20.20.9-0.3-0.60.6-0.6-0.40.4-0.4-0.4-0.30.3-0.4-1.01.00.10.8-0.8-0.50.3-0.50.2-0.2-0.10.1-0.00.1
Intermittent access intake day 1-15 change0.61.22.6-0.1-0.40.9-0.9-0.70.7-1.1-1.0-0.90.9-1.0-1.61.6-0.41.4-1.4-1.11.0-1.21.0-1.0-1.51.51.2-1.2
Intermittent access intake escalation0.61.22.5-0.1-0.70.8-0.8-0.70.7-1.1-1.1-0.90.9-1.1-1.61.6-0.51.3-1.3-1.11.0-1.21.0-1.0-1.51.51.3-1.3
Intermittent access intake escalation 20.20.21.00.4-0.3-0.10.1-0.00.0-0.3-0.2-0.10.1-0.2-0.60.6-0.00.5-0.5-0.30.2-0.40.4-0.4-0.91.00.8-0.8
Intermitt. access day 1 inactive lever presses0.83.05.5-2.0-2.31.9-1.9-1.81.8-1.9-2.0-1.81.8-2.0-1.71.7-1.51.8-1.8-2.11.9-1.91.4-1.3-0.70.61.3-1.3
Intermitt. access day 15 inactive lever presses0.10.21.5-0.8-1.20.4-0.4-0.40.4-0.5-0.6-0.40.4-0.6-0.00.0-0.6-0.20.2-0.60.5-0.50.1-0.10.4-0.40.2-0.2
Intermitt. access escalation Index0.10.10.50.50.50.0-0.00.1-0.1-0.3-0.3-0.30.3-0.30.1-0.10.1-0.20.2-0.20.3-0.40.2-0.2-0.60.70.5-0.5
Intermittent access day 1 total infusions0.50.81.9-0.1-0.7-0.90.90.6-0.50.80.80.6-0.60.81.4-1.40.1-1.21.20.7-0.70.9-0.80.81.3-1.3-0.50.4
Intermittent access day 15 total infusions0.10.11.2-0.2-1.1-0.10.1-0.10.1-0.2-0.2-0.20.2-0.20.2-0.2-0.3-0.20.2-0.30.1-0.20.1-0.1-0.10.10.7-0.7
Intermittent access terminal intake (last 3 days)0.10.20.40.1-0.5-0.50.50.3-0.30.30.30.3-0.30.30.6-0.60.1-0.60.60.2-0.30.4-0.30.30.5-0.40.0-0.0
Intermittent access total infusions0.60.71.40.3-0.3-1.01.00.7-0.70.90.90.8-0.80.91.2-1.20.4-1.01.00.7-0.90.9-0.80.81.0-1.0-0.30.3
Intermittent access day 1 locomotion0.91.11.60.40.2-1.21.20.9-0.91.21.21.1-1.11.21.3-1.30.6-1.11.11.1-1.11.2-1.01.01.2-1.2-0.70.7
Intermittent access day 15 total locomotion0.20.40.80.7-0.8-0.90.90.6-0.60.80.70.8-0.80.70.5-0.50.5-0.40.40.7-0.60.6-0.50.50.2-0.2-0.00.0
Intermittent access total locomotion0.80.91.60.7-0.5-1.31.31.0-0.91.11.01.2-1.21.01.0-1.00.7-0.80.81.1-1.01.0-1.01.01.0-1.0-0.60.6
Intermittent access standard deviation1.02.03.6-1.1-1.91.4-1.4-1.51.4-1.4-1.4-1.41.4-1.4-0.90.9-1.30.9-0.9-1.61.3-1.51.6-1.6-1.61.61.7-1.7
Left kidney weight4.119.230.7-5.5-3.35.2-5.2-5.35.3-4.9-4.8-4.84.8-4.8-3.83.8-4.83.7-3.7-4.64.7-4.64.4-4.4-2.72.52.6-2.6
Right kidney weight2.612.019.0-4.4-3.03.8-3.8-4.04.0-3.7-3.8-3.63.6-3.8-3.43.4-3.93.3-3.3-3.63.7-3.63.4-3.4-2.11.92.3-2.3
Cocaine induced anxiety0.30.42.40.41.50.5-0.6-0.30.3-0.2-0.2-0.40.4-0.20.7-0.70.1-0.70.70.0-0.0-0.40.7-0.7-1.21.20.2-0.2
Post-drug Anxiety0.80.81.7-0.4-0.11.1-1.1-0.90.8-0.9-0.9-1.01.0-0.9-0.80.8-0.60.7-0.7-0.70.6-1.01.1-1.1-1.31.30.8-0.8
Baseline Anxiety1.72.06.9-1.4-2.60.7-0.6-0.90.9-1.2-1.1-1.01.0-1.1-2.32.3-1.42.2-2.2-1.21.1-1.00.8-0.8-0.40.41.4-1.4
Tail length0.00.10.9-0.3-0.9-0.10.1-0.10.1-0.1-0.20.2-0.2-0.10.2-0.2-0.10.0-0.0-0.10.0-0.0-0.10.10.3-0.3-0.10.0
Length with tail0.10.30.7-0.9-0.80.6-0.6-0.70.7-0.6-0.5-0.60.6-0.4-0.10.1-0.70.3-0.3-0.50.4-0.40.5-0.5-0.20.20.3-0.3
Length without tail0.82.54.7-2.2-0.82.0-2.0-2.02.0-1.6-1.6-1.81.8-1.5-1.41.4-1.91.5-1.5-1.61.6-1.51.6-1.6-0.90.91.1-1.1
Times rat made contact with spout0.30.30.9-1.0-0.70.6-0.6-0.70.7-0.3-0.4-0.30.3-0.5-0.60.6-0.70.8-0.8-0.60.4-0.40.5-0.5-0.10.10.3-0.3
Lifetime Intake0.70.81.50.5-0.2-1.21.20.9-0.91.01.01.0-1.01.01.1-1.10.6-1.01.00.9-1.01.1-0.90.91.0-1.0-0.30.3
Liver weight, left0.10.20.8-0.30.2-0.10.10.0-0.0-0.1-0.00.2-0.2-0.10.9-0.90.0-0.90.90.1-0.00.1-0.30.30.7-0.7-0.60.6
Liver weight, right0.20.41.8-0.20.3-0.40.40.3-0.30.60.50.7-0.70.50.1-0.10.30.2-0.20.5-0.50.6-0.80.81.3-1.3-1.00.9
Locomotor activity0.10.21.3-0.10.00.5-0.5-0.30.30.00.10.1-0.1-0.0-1.01.00.21.1-1.1-0.10.1-0.00.1-0.1-0.10.0-0.50.5
Locomotor testing distance0.20.41.5-0.10.11.0-1.0-0.60.5-0.2-0.2-0.20.2-0.3-1.11.10.31.2-1.2-0.30.3-0.30.4-0.4-0.40.4-0.60.7
Locomotor testing rearing0.10.21.50.1-0.10.4-0.4-0.10.10.40.50.4-0.40.5-0.30.30.50.4-0.40.4-0.50.5-0.10.10.2-0.3-1.21.2
Locomotion in novel chamber2.63.35.0-1.9-1.31.9-1.9-2.02.0-1.9-1.7-2.22.2-2.0-0.60.6-2.20.5-0.5-1.82.0-2.02.1-2.2-1.91.81.8-1.8
Locomotion in novel chamber post-restriction0.50.82.7-1.5-1.70.8-0.8-1.01.0-1.0-1.3-1.21.2-0.90.1-0.1-1.4-0.40.4-0.91.0-0.80.7-0.60.1-0.10.4-0.5
Fecal boli incidents, locomotor time 10.10.21.1-0.3-0.40.1-0.1-0.10.10.0-0.2-0.00.0-0.1-0.80.8-0.21.0-1.0-0.20.5-0.00.0-0.00.1-0.10.2-0.2
Change in fecal boli incidents, locomotor task0.60.61.10.80.5-1.01.00.8-0.80.70.80.8-0.80.91.0-1.00.6-1.11.10.9-1.00.9-0.70.70.5-0.5-0.20.2
Time >=10cm from walls, locomotor time 11.11.22.70.4-1.4-0.60.60.8-0.81.31.21.0-1.01.11.0-1.01.0-0.70.71.1-0.91.1-1.21.21.5-1.6-1.61.6
Bouts of movement, locomotor time 10.91.12.30.5-1.0-1.51.51.2-1.11.21.11.2-1.21.00.4-0.40.6-0.20.21.1-1.01.0-1.21.21.4-1.3-0.80.7
Total resting periods, locomotor time 10.80.93.00.6-1.7-1.51.51.1-1.10.90.91.1-1.10.80.1-0.10.50.1-0.10.9-0.90.7-1.11.11.1-1.0-0.40.4
Rest time, locomotor task time 10.30.30.80.7-0.5-0.70.70.7-0.70.60.90.7-0.70.7-0.40.40.60.4-0.40.5-0.70.6-0.50.60.3-0.3-0.30.3
Distance moved, locomotor task time 10.20.41.8-0.41.30.6-0.6-0.50.5-0.7-0.8-0.60.6-0.70.8-0.8-0.4-0.90.9-0.30.2-0.50.4-0.4-0.20.20.1-0.1
Vertical activity count, locomotor time 10.51.23.0-1.10.81.1-1.2-1.11.1-1.6-1.7-1.21.2-1.5-0.50.5-1.10.4-0.4-1.21.2-1.31.0-1.0-0.80.71.0-1.0
Time >=10cm from walls, locomotor time 20.10.20.6-0.5-0.60.4-0.4-0.30.30.50.2-0.10.1-0.00.4-0.4-0.0-0.40.40.3-0.00.1-0.10.10.6-0.6-0.80.8
Bouts of movement, locomotor time 20.30.41.3-0.10.0-0.50.50.3-0.30.50.50.3-0.30.21.1-1.10.1-1.11.10.5-0.30.3-0.50.50.9-0.9-0.80.8
Total resting periods, locomotor time 20.20.41.40.00.3-0.60.60.4-0.40.50.50.4-0.40.31.2-1.20.1-1.11.10.5-0.30.3-0.50.50.8-0.8-0.80.7
Rest time, locomotor task time 20.20.30.80.9-0.1-0.80.80.7-0.70.20.50.6-0.60.2-0.60.60.50.7-0.70.1-0.00.1-0.30.4-0.20.30.5-0.4
Distance moved, locomotor task time 21.11.32.8-1.21.21.6-1.7-1.41.4-1.4-1.5-1.51.5-1.30.2-0.2-1.0-0.40.4-1.10.8-1.11.2-1.3-0.90.80.3-0.3
Vertical activity count, locomotor time 21.52.04.3-1.90.92.1-2.1-1.91.8-1.9-1.9-1.81.8-1.8-0.60.6-1.50.4-0.4-1.41.3-1.51.4-1.4-0.70.60.2-0.3
Light reinforcement 10.20.40.7-0.8-0.60.6-0.6-0.70.7-0.7-0.3-0.50.5-0.3-0.80.8-0.70.8-0.8-0.80.6-0.40.6-0.6-0.40.40.8-0.8
Light reinforcement 21.42.13.8-1.9-1.01.7-1.7-1.81.8-1.8-1.3-1.61.6-1.3-1.41.4-1.81.4-1.4-1.61.4-1.21.5-1.5-0.90.90.9-0.9
Bone: marrow area0.20.43.30.51.8-0.50.50.6-0.60.70.50.8-0.80.6-0.20.20.90.2-0.20.3-0.40.6-0.70.70.7-0.7-0.50.6
Bone: maximum diameter0.20.30.5-0.60.10.3-0.3-0.50.6-0.7-0.7-0.70.7-0.6-0.40.4-0.70.2-0.2-0.60.7-0.60.6-0.6-0.50.50.7-0.7
Bone: maximum force0.10.21.3-0.21.1-0.00.00.1-0.10.10.50.2-0.20.40.1-0.10.2-0.30.30.3-0.20.4-0.30.30.6-0.7-0.80.8
Bone: maximum moment0.10.10.7-0.40.80.2-0.2-0.10.1-0.10.3-0.10.10.2-0.10.10.0-0.10.10.10.00.2-0.20.20.5-0.6-0.80.7
Mean time between licks in bursts1.43.55.91.30.4-1.51.51.6-1.61.82.01.7-1.72.12.3-2.31.6-2.42.42.1-2.02.0-1.81.81.8-1.8-2.12.0
Mean num. licks in bursts0.10.10.7-0.40.50.2-0.2-0.20.20.00.00.1-0.10.0-0.00.00.1-0.00.00.0-0.10.2-0.10.10.5-0.6-0.80.8
Cd content in liver0.91.02.51.00.4-0.50.50.8-0.81.20.91.3-1.30.91.0-1.01.4-0.80.81.0-1.00.9-1.01.00.9-1.0-1.51.6
Co content in liver0.20.31.5-0.3-0.80.6-0.6-0.30.20.2-0.20.1-0.1-0.20.6-0.60.3-0.50.50.00.2-0.2-0.20.20.7-0.8-1.21.2
Cu content in liver0.50.62.40.5-0.2-0.00.00.5-0.51.00.70.7-0.70.60.3-0.31.1-0.30.30.8-0.70.6-0.90.91.1-1.1-1.51.5
Fe content in liver1.82.25.6-2.0-1.81.6-1.6-1.61.6-1.0-1.5-1.21.2-1.6-2.22.2-1.22.4-2.4-1.31.5-1.41.0-1.0-0.20.10.4-0.4
K content in liver0.10.10.70.10.80.1-0.10.1-0.10.40.3-0.00.00.30.1-0.10.2-0.10.10.4-0.30.4-0.20.20.3-0.3-0.50.5
Mg content in liver0.80.91.6-0.4-0.40.8-0.8-0.70.7-0.8-0.8-1.01.0-0.8-1.01.0-0.81.0-1.0-0.80.8-0.91.0-1.0-1.31.31.2-1.2
Mn content in liver0.30.42.50.91.6-0.30.30.5-0.60.60.50.4-0.40.50.7-0.70.7-0.80.80.6-0.50.5-0.40.40.0-0.0-0.20.3
Na content in liver0.60.61.60.11.30.2-0.20.2-0.20.40.80.1-0.10.71.1-1.10.5-1.31.30.6-0.70.8-0.50.50.7-0.8-1.21.2
Rb content in liver0.10.10.4-0.2-0.6-0.10.10.0-0.00.00.00.2-0.2-0.1-0.30.30.00.6-0.6-0.00.1-0.1-0.20.20.4-0.4-0.30.2
Se content in liver0.30.31.3-0.80.50.6-0.6-0.30.30.50.6-0.20.20.4-0.30.3-0.10.5-0.50.4-0.40.7-0.10.10.8-0.9-1.11.1
Sr content in liver0.10.10.3-0.0-0.50.3-0.3-0.20.10.5-0.30.3-0.3-0.3-0.50.50.20.2-0.2-0.00.3-0.30.0-0.00.0-0.0-0.10.2
Zn content in liver1.01.12.21.40.3-0.90.91.1-1.11.51.51.1-1.11.40.6-0.61.3-0.60.61.4-1.41.3-0.90.90.3-0.3-0.80.8
Bone: minimum diameter0.20.41.2-0.9-0.90.7-0.7-0.60.6-0.5-0.6-0.50.5-0.6-1.11.1-0.30.8-0.8-0.60.7-0.60.2-0.20.4-0.4-0.10.2
Time in familiar zone, hab. session 10.20.21.70.21.30.5-0.5-0.20.2-0.10.1-0.10.10.30.1-0.10.3-0.20.20.2-0.40.40.2-0.2-0.30.3-0.70.7
Time in novel zone, hab. session 10.60.63.00.3-1.7-0.70.80.7-0.70.80.50.9-0.90.40.1-0.10.70.2-0.20.4-0.30.3-1.01.01.2-1.2-0.50.5
Total zone transitions, hab. session 10.10.21.6-0.6-1.3-0.10.1-0.00.00.00.10.2-0.20.10.1-0.1-0.20.2-0.20.0-0.00.2-0.30.30.9-0.9-0.50.4
Total locomotion distance, hab. session 10.40.60.9-0.9-0.50.8-0.8-0.90.9-0.9-0.8-0.70.7-0.9-0.40.4-0.90.9-0.9-1.00.9-0.80.7-0.7-0.50.40.4-0.5
Locomotion velocity, hab. session 10.20.30.5-0.5-0.20.3-0.3-0.40.5-0.6-0.5-0.40.4-0.6-0.20.2-0.70.6-0.6-0.70.6-0.50.5-0.5-0.50.50.6-0.7
Time in familiar zone, hab. session 20.10.10.50.20.10.3-0.3-0.00.00.2-0.00.1-0.10.00.3-0.30.5-0.50.50.0-0.00.1-0.10.10.2-0.2-0.70.7
Time in novel zone, hab. session 20.10.10.30.10.3-0.40.40.4-0.40.30.60.4-0.40.50.2-0.20.20.2-0.20.5-0.50.6-0.40.40.4-0.4-0.40.3
Total zone transitions, hab. session 20.10.21.0-0.80.20.2-0.2-0.30.3-0.10.1-0.00.00.20.5-0.5-0.4-0.20.20.1-0.20.4-0.10.10.7-0.7-1.00.9
Total locomotion distance, hab. session 20.50.71.4-1.2-0.11.0-1.0-1.11.1-1.0-0.8-0.90.9-0.8-0.40.4-1.10.6-0.6-0.90.7-0.61.0-1.0-0.60.60.1-0.2
Locomotion velocity, hab. session 20.81.12.1-1.5-0.51.2-1.2-1.31.3-1.3-1.0-1.21.2-1.1-0.60.6-1.40.9-0.9-1.11.0-0.91.2-1.2-0.80.70.4-0.5
Novel to familiar place preference ratio0.91.02.6-0.3-0.60.6-0.6-0.60.6-0.7-0.5-0.50.5-0.5-1.61.6-0.61.6-1.6-0.90.6-0.70.9-0.9-1.21.21.6-1.5
Novelty place preference0.60.72.1-0.2-0.80.4-0.4-0.40.4-0.5-0.3-0.30.3-0.3-1.41.4-0.41.4-1.4-0.60.4-0.50.6-0.6-0.90.91.3-1.2
Time in novel zone, NPP test0.50.51.9-0.1-0.60.3-0.3-0.30.3-0.3-0.1-0.20.2-0.1-1.41.4-0.21.3-1.3-0.50.2-0.30.5-0.5-0.70.71.1-1.0
Total zone transitions, NPP test0.40.62.6-1.6-0.91.0-1.0-1.11.1-1.0-0.8-0.80.8-0.6-0.20.2-1.10.5-0.5-0.80.8-0.50.6-0.60.2-0.3-0.40.3
Total locomotion distance, NPP test1.01.42.4-1.5-0.31.4-1.4-1.51.5-1.4-1.2-1.31.3-1.2-0.80.8-1.41.1-1.1-1.31.2-1.01.3-1.3-0.90.80.5-0.5
Locomotion velocity, NPP test1.52.13.4-1.8-0.61.7-1.7-1.81.8-1.8-1.6-1.61.6-1.5-0.90.9-1.81.1-1.1-1.61.6-1.41.7-1.7-1.21.10.8-0.8
Intraocular pressure0.10.20.80.30.9-0.00.00.0-0.00.00.0-0.30.30.1-0.30.3-0.20.5-0.5-0.1-0.1-0.00.3-0.3-0.70.80.8-0.8
Delta distance traveled before/after self-admin0.50.62.80.1-0.40.3-0.3-0.50.5-0.7-0.7-0.70.7-0.7-0.20.2-0.70.1-0.1-0.40.2-0.71.1-1.1-1.61.71.1-1.1
Delta ambulatory time before/after self-admin0.30.31.70.3-0.60.1-0.1-0.30.2-0.4-0.4-0.50.5-0.40.6-0.6-0.5-0.50.5-0.0-0.2-0.40.7-0.8-1.31.30.7-0.7
Parametrial fat weight0.10.21.10.20.3-0.10.1-0.10.1-0.0-0.1-0.00.0-0.1-0.20.2-0.30.2-0.20.10.2-0.20.6-0.6-1.01.10.7-0.7
Pavlov. Cond. lever latency1.72.23.71.91.3-1.61.61.7-1.71.81.61.7-1.71.51.1-1.11.8-1.31.31.7-1.51.4-1.41.40.8-0.8-1.21.2
Pavlov. Cond. magazine entry latency0.60.81.20.7-0.1-0.90.90.9-0.90.90.91.0-1.01.00.9-0.90.8-0.80.81.0-1.11.1-1.01.00.9-0.9-0.70.7
Pavlov. Cond. change in total contacts0.00.00.1-0.20.00.1-0.1-0.10.1-0.10.3-0.20.20.30.2-0.2-0.2-0.10.10.1-0.20.20.1-0.1-0.00.00.0-0.0
Pavlov. Cond. index score0.20.30.8-0.9-0.70.6-0.6-0.60.6-0.7-0.6-0.60.6-0.5-0.30.3-0.70.4-0.4-0.70.5-0.40.4-0.4-0.00.00.4-0.4
Pavlov. Cond. latency score0.30.41.0-1.0-0.80.7-0.7-0.70.7-0.9-0.7-0.80.8-0.7-0.30.3-0.90.4-0.4-0.80.6-0.50.5-0.5-0.10.10.6-0.6
Pavlov. Cond. lever contacts1.41.62.5-1.6-1.41.3-1.3-1.41.4-1.5-1.4-1.41.4-1.4-1.01.0-1.51.2-1.2-1.51.3-1.21.2-1.2-0.70.71.1-1.1
Pavlov. Cond. magazine entry number0.40.50.8-0.40.50.7-0.7-0.70.7-0.7-0.7-0.70.7-0.9-0.70.7-0.50.6-0.6-0.80.9-0.90.7-0.7-0.80.80.6-0.6
Pavlov. Cond. intertrial magazine entries1.31.53.9-0.1-0.10.6-0.6-0.70.7-0.8-0.9-0.90.9-1.0-1.51.5-0.81.8-1.8-0.91.0-1.11.3-1.3-1.92.01.9-1.8
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.9-0.60.8-0.8-0.80.8-0.9-0.8-0.80.8-0.7-0.40.4-0.80.5-0.5-0.80.7-0.60.6-0.6-0.30.30.6-0.6
Pavlov. Cond. response bias0.10.11.0-0.6-1.00.4-0.4-0.30.3-0.2-0.1-0.10.10.1-0.20.2-0.30.4-0.4-0.2-0.10.20.0-0.00.4-0.4-0.20.2
Pavlov. Cond. lever latency0.40.67.3-1.3-2.70.4-0.4-0.50.5-0.4-0.9-0.30.3-0.7-0.30.3-0.60.4-0.4-0.60.6-0.6-0.10.11.0-1.00.0-0.1
Pavlov. Cond. magazine entry latency1.82.15.92.02.4-1.11.11.3-1.41.41.61.3-1.31.51.8-1.81.7-1.71.71.5-1.51.3-1.01.00.2-0.2-1.31.4
Pavlov. Cond. change in total contacts0.71.111.91.63.4-0.60.50.7-0.70.50.90.4-0.40.90.9-0.90.8-0.90.90.7-0.90.80.0-0.0-1.01.1-0.00.1
Pavlov. Cond. index score1.21.69.41.93.1-0.90.91.1-1.11.11.51.0-1.01.31.3-1.31.4-1.11.11.2-1.31.2-0.60.5-0.40.4-0.80.8
Pavlov. Cond. latency score1.11.49.51.83.1-0.80.81.0-1.01.01.40.8-0.81.21.3-1.31.3-1.21.21.1-1.21.1-0.50.4-0.40.4-0.80.8
Pavlov. Cond. lever contacts0.40.56.21.22.5-0.30.30.4-0.50.40.80.3-0.30.70.1-0.10.7-0.10.10.5-0.60.50.1-0.1-0.91.0-0.10.2
Pavlov. Cond. magazine entry number2.02.57.1-1.9-2.71.4-1.4-1.51.6-1.4-1.6-1.31.3-1.5-2.02.0-1.71.9-1.9-1.51.5-1.41.3-1.3-0.70.61.4-1.4
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.1-0.2-0.20.20.2-0.20.00.20.0-0.00.4-0.20.2-0.10.1-0.10.1-0.30.4-0.20.20.3-0.30.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.31.89.82.03.1-1.01.01.2-1.21.21.61.1-1.11.41.4-1.41.5-1.21.21.3-1.41.3-0.70.7-0.20.3-1.01.0
Pavlov. Cond. response bias0.81.17.31.72.7-0.80.81.0-1.00.81.30.7-0.71.10.9-0.91.2-0.80.81.0-1.11.0-0.50.5-0.40.4-0.70.7
Time in closed arm before self-admin0.81.04.01.42.0-0.90.90.9-0.91.11.00.7-0.71.01.6-1.60.8-1.11.11.2-1.11.0-0.30.3-0.40.5-0.00.1
Time in closed arm after self-admin0.80.91.70.61.1-0.70.70.8-0.80.80.90.8-0.80.91.3-1.30.8-1.01.00.9-0.90.8-0.90.91.0-1.0-1.21.2
Time in open arm before self-admin0.91.03.3-1.0-1.21.0-1.0-0.80.8-1.0-1.1-0.60.6-1.1-1.81.8-0.41.4-1.4-1.11.0-1.00.4-0.40.1-0.10.0-0.0
Time in open arm after self-admin0.60.71.4-0.6-1.10.5-0.5-0.60.6-0.6-0.8-0.80.8-0.7-1.21.2-0.81.0-1.0-0.80.8-0.70.7-0.7-0.70.71.1-1.1
Bone: periosteal estimation0.20.30.9-0.90.60.6-0.6-0.70.7-0.6-0.6-0.60.6-0.5-0.80.8-0.50.6-0.6-0.60.7-0.50.4-0.40.1-0.10.1-0.1
Bone: periosteal perimeter0.20.30.8-0.60.00.4-0.4-0.50.6-0.6-0.6-0.50.5-0.6-0.90.9-0.50.7-0.7-0.60.7-0.60.5-0.5-0.40.40.4-0.4
Bone: post-yield work0.20.32.00.51.4-0.60.60.5-0.50.20.60.6-0.60.70.5-0.50.5-0.20.20.2-0.60.6-0.40.40.2-0.2-0.10.2
Progressive ratio test 1 active lever presses0.10.10.3-0.4-0.5-0.20.2-0.10.10.00.0-0.10.10.00.5-0.5-0.4-0.40.4-0.1-0.00.10.0-0.00.3-0.30.4-0.4
Progressive ratio test 1 breakpoint0.10.10.3-0.5-0.5-0.20.2-0.10.10.00.0-0.10.10.00.5-0.5-0.4-0.50.5-0.10.00.00.0-0.00.3-0.30.4-0.4
Progressive ratio test 1 inactive lever presses0.10.11.3-0.8-1.20.1-0.1-0.30.3-0.1-0.1-0.20.2-0.10.1-0.1-0.4-0.10.1-0.20.10.1-0.10.10.6-0.6-0.0-0.0
Progressive ratio test 2 active lever presses0.10.10.40.0-0.6-0.40.40.0-0.00.30.20.3-0.30.20.4-0.4-0.0-0.20.20.1-0.20.20.0-0.0-0.10.10.5-0.5
Progressive ratio test 2 breakpoint0.10.10.40.1-0.7-0.40.40.1-0.10.30.20.3-0.30.20.5-0.5-0.0-0.30.30.1-0.30.20.0-0.0-0.10.10.5-0.5
Progressive ratio test 2 inactive lever presses0.10.10.30.3-0.0-0.50.50.3-0.30.50.40.4-0.40.40.3-0.30.1-0.20.20.3-0.40.4-0.10.1-0.10.10.5-0.4
Incentive Sensitization - Responses0.20.30.80.8-0.0-0.90.90.5-0.50.50.40.7-0.70.40.5-0.50.3-0.20.20.4-0.50.3-0.10.1-0.50.50.6-0.6
Incentive Sensitization - Breakpoint0.20.30.70.8-0.1-0.80.80.5-0.50.50.40.7-0.70.40.5-0.50.4-0.20.20.4-0.50.3-0.10.1-0.50.50.6-0.5
Sum of active levers in priming session hrs 5-60.90.82.4-1.5-1.21.1-1.1-1.01.0-1.2-1.3-1.01.0-1.2-0.40.4-0.80.3-0.3-1.11.2-1.00.3-0.30.6-0.6-0.30.3
Progressive ratio0.81.22.9-0.4-1.30.6-0.6-0.80.8-1.2-1.0-1.01.0-1.3-0.40.4-1.00.4-0.4-1.11.2-1.51.1-1.1-1.51.51.7-1.7
Food seeking constrained by brief footshock2.32.84.31.71.3-1.91.91.9-1.91.61.62.0-2.01.51.0-1.02.0-1.11.11.6-1.31.6-2.12.11.9-1.9-1.71.7
Seeking ratio, punishment vs. effort3.34.78.51.62.7-1.71.82.0-2.02.22.12.3-2.32.31.1-1.12.4-1.01.02.1-2.22.6-2.42.42.5-2.6-2.92.9
Retroperitoneal fat weight0.31.42.41.61.2-1.51.51.4-1.41.31.41.2-1.21.51.3-1.31.0-1.21.21.4-1.41.3-0.90.90.3-0.2-0.20.2
Reaction time number correct0.00.10.70.0-0.8-0.20.20.2-0.10.20.10.2-0.20.20.2-0.20.1-0.10.1-0.1-0.10.1-0.20.20.3-0.30.2-0.2
Reaction time mean minus median0.10.41.01.0-0.4-0.80.80.8-0.80.30.10.4-0.40.11.0-1.00.6-1.01.00.3-0.1-0.0-0.50.50.00.0-0.0-0.0
Reaction time mean minus median AUC0.10.21.10.6-1.1-0.50.50.6-0.50.2-0.10.3-0.3-0.10.5-0.50.5-0.60.60.10.1-0.2-0.40.40.2-0.2-0.10.1
Reaction time num false alarms0.81.11.7-1.1-0.31.2-1.2-1.21.2-1.0-1.2-1.11.1-1.1-0.60.6-1.20.4-0.4-0.81.2-1.11.3-1.3-1.21.10.8-0.8
Reaction time num false alarms AUC1.21.92.8-1.5-0.71.6-1.6-1.71.7-1.4-1.5-1.51.5-1.4-1.01.0-1.60.7-0.7-1.21.5-1.41.6-1.6-1.31.31.0-1.0
Reaction time trials correct on left0.00.10.70.0-0.8-0.20.20.2-0.10.20.10.2-0.20.20.2-0.20.1-0.10.1-0.1-0.10.1-0.20.20.3-0.30.2-0.2
Reaction time trials on left0.00.10.70.1-0.8-0.20.20.2-0.20.20.10.2-0.20.20.2-0.20.1-0.10.1-0.1-0.10.1-0.20.20.2-0.20.3-0.3
Reaction time mean0.30.51.71.00.1-1.31.31.1-1.00.60.40.8-0.80.40.9-0.90.5-0.80.80.6-0.40.4-0.70.70.2-0.10.2-0.2
Reaction time mean AUC0.40.71.61.00.0-1.31.31.1-1.10.80.50.9-0.90.61.0-1.00.6-1.01.00.7-0.50.5-0.90.90.6-0.5-0.20.1
Median of all reaction times0.40.61.91.00.4-1.41.41.1-1.10.70.60.9-0.90.60.8-0.80.4-0.80.80.7-0.60.6-0.70.70.3-0.20.3-0.3
Reaction time omissions0.10.10.7-0.1-0.7-0.30.30.1-0.0-0.4-0.3-0.30.3-0.30.0-0.0-0.50.1-0.1-0.20.4-0.40.1-0.1-0.20.30.8-0.8
Reaction time false alarm rate1.31.92.8-1.5-0.31.6-1.6-1.71.7-1.5-1.5-1.51.5-1.4-1.11.1-1.60.9-0.9-1.11.5-1.41.6-1.6-1.31.30.7-0.8
Reaction time premature initiation rate0.20.31.11.10.2-0.40.40.6-0.60.80.80.7-0.70.7-0.20.20.90.3-0.30.7-0.60.6-0.30.3-0.20.2-0.50.5
Reaction time premature initiations0.30.51.41.2-0.0-0.60.70.8-0.81.01.00.9-0.91.00.3-0.31.1-0.00.00.8-0.90.8-0.60.60.1-0.1-0.50.6
Std. dev. reaction times0.20.41.20.70.1-0.70.70.7-0.70.30.20.4-0.40.31.1-1.10.4-1.11.10.4-0.20.2-0.50.50.3-0.2-0.20.2
Reaction time trials completed0.00.10.70.1-0.8-0.20.20.2-0.20.20.10.2-0.20.20.2-0.20.1-0.10.1-0.1-0.10.1-0.20.20.2-0.20.3-0.3
Reaction time trials AUC0.00.00.7-0.1-0.8-0.00.00.0-0.00.10.00.1-0.10.00.1-0.1-0.00.0-0.0-0.20.0-0.0-0.10.10.1-0.10.3-0.3
Run reversals in cocaine runway, females0.60.61.40.90.9-1.11.20.8-0.81.11.10.9-0.91.1-0.10.10.3-0.10.11.1-1.20.9-0.40.4-0.10.20.2-0.2
Run reversals in cocaine runway, males1.81.83.1-1.2-0.91.6-1.6-1.51.5-1.6-1.8-1.41.4-1.7-0.90.9-1.20.9-0.9-1.61.6-1.61.4-1.4-1.21.20.8-0.8
Latency to leave start box in cocaine runway0.30.30.7-0.60.20.4-0.5-0.60.6-0.8-0.6-0.50.5-0.7-0.20.2-0.7-0.00.0-0.80.8-0.70.7-0.7-0.60.60.8-0.8
Latency to leave start box in cocaine runway, F1.31.52.2-0.9-0.41.1-1.1-1.11.1-1.5-1.3-1.21.2-1.3-1.01.0-1.20.8-0.8-1.31.3-1.41.3-1.3-1.41.41.4-1.4
Latency to leave start box in cocaine runway, M0.50.50.80.30.5-0.80.80.6-0.60.60.60.9-0.90.60.7-0.70.5-0.90.90.4-0.50.7-0.70.80.9-0.9-0.60.6
Std. dev. time between licks in bursts2.73.65.51.72.0-1.81.81.8-1.81.82.31.8-1.82.22.3-2.31.6-2.32.32.1-2.12.1-1.61.61.3-1.3-1.51.5
Total sessions with >9 infusions1.21.52.70.70.2-1.61.61.1-1.11.31.31.2-1.21.31.6-1.60.6-1.51.51.3-1.31.3-1.11.11.1-1.0-0.50.4
Short access day 1 total inactive lever presses1.92.53.5-1.4-1.11.5-1.5-1.61.6-1.6-1.5-1.61.6-1.5-1.81.8-1.51.9-1.9-1.61.5-1.51.6-1.6-1.51.51.8-1.8
Short access day 10 total inactive lever presses0.81.94.8-1.5-1.51.3-1.3-1.31.3-1.2-1.2-1.01.0-1.2-2.22.2-1.12.0-2.0-1.51.2-1.21.0-1.0-0.50.50.9-0.9
Short access day 1 total infusions0.20.20.80.2-0.8-0.90.90.4-0.40.40.40.6-0.60.4-0.30.30.10.4-0.40.3-0.40.4-0.40.40.3-0.30.4-0.4
Short access day 10 total infusions0.30.31.2-0.4-0.2-0.60.60.3-0.20.50.40.4-0.40.40.8-0.8-0.1-0.80.80.4-0.50.6-0.60.61.1-1.1-0.40.4
Short access total infusions0.70.92.00.3-0.1-1.41.40.9-0.91.11.11.1-1.11.10.7-0.70.5-0.60.61.0-1.21.2-1.01.01.2-1.2-0.30.3
Short access day 1 locomotion0.00.00.10.10.1-0.30.30.0-0.00.10.10.3-0.30.1-0.00.00.00.0-0.00.0-0.10.1-0.00.00.0-0.00.3-0.3
Short access day 10 total locomotion0.20.31.3-0.7-1.20.1-0.1-0.40.5-0.5-0.6-0.40.4-0.6-0.30.3-0.90.6-0.6-0.50.5-0.70.5-0.5-0.40.40.9-1.0
Short access total locomotion0.80.91.50.50.5-1.21.20.9-0.91.11.01.1-1.11.01.1-1.10.7-1.01.01.0-1.01.1-1.01.01.1-1.1-0.60.6
One hour access (0.3 mA shock)0.81.01.81.30.6-1.11.11.1-1.11.01.01.1-1.11.01.2-1.21.2-1.21.20.8-0.80.8-0.90.90.4-0.4-0.50.5
Compulsive drug intake0.30.40.70.60.6-0.70.70.8-0.80.60.50.7-0.70.50.0-0.00.7-0.10.10.6-0.50.6-0.90.90.8-0.8-0.60.6
One hour access (shock baseline)0.10.20.6-0.1-0.10.4-0.4-0.50.4-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.20.2-0.50.4-0.40.6-0.6-0.80.80.6-0.6
Social response proportion0.60.71.51.20.6-0.90.90.9-0.91.00.91.1-1.10.90.7-0.70.9-1.01.01.0-0.90.8-0.60.60.1-0.0-0.30.4
Social responses0.91.21.91.41.4-1.01.01.0-1.01.31.21.2-1.21.11.2-1.21.2-1.21.21.3-1.11.1-0.80.80.3-0.3-1.01.0
Social time0.40.51.8-1.3-0.31.0-1.0-1.01.0-0.7-0.7-0.70.7-0.5-0.70.7-0.90.6-0.6-0.60.6-0.40.7-0.7-0.0-0.00.1-0.1
Soleus weight2.88.112.4-1.9-0.43.5-3.5-3.13.0-3.2-3.1-3.23.2-3.0-2.12.1-2.22.4-2.4-3.03.0-3.13.3-3.3-3.53.42.0-2.0
Bone: stiffness0.10.21.70.11.3-0.50.50.4-0.40.40.70.4-0.40.60.0-0.00.2-0.30.30.5-0.50.6-0.40.40.5-0.4-0.10.1
Tibialis anterior weight3.010.014.0-3.6-1.73.6-3.7-3.73.7-3.7-3.4-3.73.7-3.3-2.52.5-3.52.5-2.5-3.53.3-3.13.4-3.4-2.52.42.4-2.4
Time to tail flick, vehicle, before self-admin1.21.32.0-1.3-0.61.1-1.1-1.11.1-1.1-1.2-1.21.2-1.2-1.31.3-1.31.4-1.4-1.20.8-0.81.1-1.1-0.80.81.3-1.3
Time to tail flick, vehicle, after self-admin0.60.81.4-1.0-0.40.8-0.8-1.01.0-1.1-1.1-1.01.0-1.0-0.30.3-1.20.4-0.4-0.81.0-0.91.1-1.1-0.90.90.7-0.7
Time to tail flick, test, before self-admin1.41.42.7-0.4-0.21.3-1.3-1.11.0-1.1-1.2-1.11.1-1.2-1.41.4-0.71.4-1.4-1.11.2-1.21.3-1.3-1.71.61.0-1.0
Time to tail flick, test, after self-admin1.81.86.6-1.6-2.61.6-1.6-1.51.5-1.3-1.4-1.41.4-1.4-1.01.0-1.31.1-1.1-1.51.4-1.31.2-1.2-0.80.70.9-0.9
Delta time to tail flick, vehicle, before/after SA0.50.41.1-0.6-0.50.7-0.7-0.80.8-0.9-0.8-0.70.7-0.80.1-0.1-0.7-0.10.1-0.61.0-0.90.8-0.8-0.70.70.2-0.3
Delta time to tail flick, test, before/after SA0.10.12.0-0.6-1.40.1-0.1-0.20.2-0.1-0.0-0.20.2-0.00.3-0.3-0.4-0.20.2-0.30.1-0.10.0-0.00.4-0.40.1-0.1
Tibia length0.00.10.6-0.10.80.1-0.1-0.00.1-0.4-0.2-0.40.4-0.1-0.30.3-0.30.2-0.2-0.30.1-0.00.2-0.2-0.30.30.6-0.6
Ambulatory time before self-admin0.81.24.5-2.1-0.51.8-1.8-1.61.6-0.8-0.9-1.01.0-0.9-1.01.0-1.01.1-1.1-0.91.0-0.50.7-0.70.5-0.6-0.60.6
Ambulatory time after self-admin0.60.71.7-1.3-1.11.3-1.3-1.31.3-0.7-0.7-0.90.9-0.6-0.10.1-0.90.4-0.4-0.40.3-0.41.0-1.0-0.50.4-0.20.2
Bone: tissue strength1.51.54.01.52.0-0.90.91.1-1.11.11.41.2-1.21.51.3-1.31.5-1.41.41.4-1.51.4-0.90.90.5-0.5-1.21.2
Total heroin consumption0.50.61.60.3-0.5-0.90.90.7-0.70.30.40.7-0.70.41.3-1.30.4-1.31.30.4-0.50.3-0.70.70.9-0.8-0.30.2
Bone: trabecular number1.22.06.7-0.2-0.2-0.80.70.8-0.81.11.21.0-1.01.31.1-1.10.9-1.31.31.3-1.21.5-1.61.62.5-2.6-2.32.2
Bone: trabecular spacing1.52.05.9-0.60.31.1-1.1-1.31.3-1.1-1.3-1.21.2-1.4-0.70.7-1.41.1-1.1-1.41.3-1.51.9-1.9-2.42.41.8-1.8
Bone: trabecular thickness1.21.43.9-0.00.5-0.40.40.6-0.60.71.00.5-0.51.21.4-1.40.7-1.71.71.0-1.21.3-1.21.21.9-1.9-2.01.9
Bone: trabecular tissue density0.20.41.20.7-0.40.2-0.3-0.00.0-0.0-0.5-0.30.3-0.51.1-1.10.1-0.90.90.10.4-0.70.5-0.5-1.11.10.2-0.2
Water consumed over 24 hours0.40.52.1-1.4-0.61.0-1.0-0.90.9-0.3-0.4-0.50.5-0.4-0.80.8-0.60.8-0.8-0.40.3-0.10.3-0.30.6-0.7-0.70.7
Number of responses in last shaping day1.11.23.3-1.8-1.11.4-1.4-1.51.5-1.0-1.0-1.11.1-1.0-1.01.0-1.31.1-1.1-1.10.9-0.81.0-1.0-0.20.10.3-0.3