Hub : Genes

Ttc4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio NM_001395043.1 0.08 0.05 4.6e-03 0.02 0.04 0.01 0.02 3.6e-02 8.3e-03 1.6e-01 4.9e-02
2 pVTA isoform ratio XM_039110294.1 0.08 0.05 4.0e-03 0.03 0.04 0.01 0.02 3.0e-02 7.6e-03 1.7e-01 4.5e-02
3 Adipose gene expression Ttc4 0.04 0.03 1.7e-03 0.01 0.01 0 0.01 1.6e-02 1.6e-02 1.1e-01 4.0e-02
4 pVTA gene expression Ttc4 0.22 0.11 7.7e-06 0.08 0.12 0.1 0.09 2.6e-04 8.1e-06 3.9e-05 1.3e-04
5 Brain gene expression Ttc4 0.05 0.03 2.2e-05 0.06 0.06 0.06 0.06 3.4e-06 5.0e-06 2.2e-06 2.6e-06
6 Brain isoform ratio NM_001395043.1 0.07 0.04 7.3e-08 0.09 0.09 0.08 0.08 2.3e-08 1.3e-08 9.1e-08 4.3e-08
7 Brain isoform ratio XM_039110294.1 0.07 0.04 6.3e-08 0.09 0.09 0.08 0.08 2.4e-08 1.3e-08 7.7e-08 3.7e-08
8 Liver gene expression Ttc4 0.08 0.04 2.4e-07 0.04 0.03 0.02 0.03 8.6e-06 2.2e-04 2.2e-03 8.1e-04
9 Brain alternative TSS XM_039110294.1 0.1 0.04 4.0e-11 0.11 0.12 0.11 0.11 1.8e-10 2.6e-11 2.4e-10 1.5e-10
10 Brain alternative TSS NM_001395043.1 0.1 0.04 3.6e-11 0.11 0.12 0.11 0.11 2.2e-10 2.5e-11 1.8e-10 1.5e-10
11 BLA alternative TSS XM_039110294.1 0.06 0.04 9.1e-03 0.03 0.03 0.02 0.02 1.1e-02 1.7e-02 4.6e-02 2.6e-02
12 NAcc isoform ratio NM_001395043.1 0.05 0.03 1.1e-04 0.04 0.03 0.04 0.04 6.6e-06 2.4e-04 4.4e-05 1.6e-05
13 NAcc isoform ratio XM_039110294.1 0.05 0.03 1.3e-04 0.04 0.03 0.03 0.04 9.3e-06 3.5e-04 8.7e-05 3.2e-05
14 PL gene expression Ttc4 0.02 0.02 9.6e-03 0.01 0.01 0.01 0.01 1.1e-02 1.9e-02 7.0e-02 2.8e-02
15 PL alternative TSS XM_039110294.1 0.03 0.02 1.6e-04 0.03 0.03 0.03 0.03 5.4e-04 3.9e-04 3.2e-04 4.8e-04
16 NAcc alternative TSS NM_001395043.1 0.1 0.05 1.9e-09 0.09 0.07 0.08 0.08 1.4e-10 4.4e-09 2.5e-09 1.2e-09
17 NAcc alternative TSS XM_039110294.1 0.08 0.04 4.3e-09 0.09 0.07 0.08 0.08 9.7e-11 4.3e-09 2.7e-09 1.9e-09
18 NAcc gene expression Ttc4 0.14 0.07 1.2e-13 0.13 0.12 0.12 0.12 1.4e-14 7.2e-14 2.0e-13 3.6e-14
19 OFC gene expression Ttc4 0.27 0.13 3.4e-04 0.17 0.09 0.1 0.15 6.4e-05 3.5e-03 2.9e-03 1.9e-04
20 PL alternative TSS NM_001395043.1 0.03 0.02 1.6e-04 0.03 0.03 0.03 0.03 4.0e-04 3.5e-04 4.5e-04 4.1e-04
21 pVTA alternative TSS XM_039110294.1 0.1 0.06 9.7e-04 0.05 0.07 0.05 0.05 2.6e-03 7.1e-04 2.3e-03 4.1e-03
22 pVTA alternative TSS NM_001395043.1 0.09 0.06 1.3e-03 0.04 0.06 0.04 0.04 5.4e-03 1.3e-03 5.3e-03 5.5e-03
23 PL isoform ratio NM_001395043.1 0.03 0.02 1.6e-03 -0 0.01 0.01 0 5.1e-01 1.2e-02 7.1e-02 2.6e-01
24 PL isoform ratio XM_039110294.1 0.03 0.02 1.2e-03 -0 0.01 0.01 0 4.3e-01 7.0e-03 5.2e-02 2.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.50.93.20.1-0.10.20.2-0.50.4-0.4-1.3-0.70.71.5-0.90.9-0.90.7-0.90.9-0.9-1.11.1-1.11.11.8-1.8
Area under the delay curve0.10.10.70.2-0.20.20.1-0.70.4-0.4-0.3-0.30.30.8-0.20.2-0.20.1-0.10.1-0.1-0.40.10.3-0.30.0-0.0
BMI with tail0.41.42.6-1.61.6-1.6-1.51.3-1.31.31.51.2-1.2-0.51.2-1.21.2-1.31.2-1.21.20.6-1.01.1-1.1-0.20.2
BMI without tail0.30.61.40.5-0.50.60.6-0.50.8-0.8-0.5-0.90.91.1-0.70.7-0.70.7-0.70.7-0.7-1.00.9-0.80.81.2-1.2
Body weight0.31.32.5-1.51.5-1.5-1.61.3-1.11.01.41.1-1.0-0.41.0-1.01.0-1.21.0-1.01.00.6-1.01.3-1.3-0.30.4
Weight adjusted by age0.40.50.9-0.50.5-0.5-0.50.6-0.70.70.90.7-0.7-0.90.8-0.80.8-0.60.7-0.70.70.5-0.80.7-0.7-0.90.9
Bone surface0.20.31.50.2-0.30.30.3-0.30.4-0.4-0.9-0.40.41.2-0.50.5-0.50.3-0.50.5-0.5-0.60.5-0.40.40.6-0.6
Bone volume0.10.10.5-0.50.5-0.5-0.40.3-0.20.2-0.50.1-0.10.70.0-0.00.0-0.20.0-0.00.0-0.10.1-0.00.10.6-0.6
Breakpoint value in progressive ratio session0.30.31.10.2-0.30.30.2-0.50.6-0.6-0.8-0.60.60.4-0.40.4-0.40.6-0.40.4-0.4-0.70.8-0.60.61.1-1.1
Number of licking bursts0.50.61.2-0.60.6-0.7-0.80.4-0.60.60.20.7-0.7-1.10.8-0.80.8-0.80.8-0.80.81.1-0.91.1-1.1-1.01.0
Context. condit. distance diff. score0.40.42.4-0.20.2-0.1-0.10.20.0-0.00.4-0.30.30.6-0.50.5-0.50.5-0.50.5-0.5-0.50.8-1.01.01.5-1.5
Locomotion velocity, session 11.61.73.51.2-1.21.21.1-1.31.3-1.3-1.2-1.31.31.9-1.31.3-1.31.3-1.31.3-1.3-1.51.3-1.21.21.3-1.3
Locomotion distance, session 10.00.10.4-0.30.3-0.3-0.40.0-0.10.1-0.20.0-0.00.60.2-0.20.2-0.00.2-0.20.2-0.10.10.1-0.00.4-0.4
Locomotion velocity, session 20.91.11.61.1-1.11.11.0-1.01.1-1.1-1.0-1.11.11.3-1.01.0-1.01.1-1.01.0-1.0-1.21.0-1.01.00.9-0.9
Locomotion distance, session 20.60.91.1-1.01.0-1.0-1.00.6-1.01.0-0.11.0-1.00.01.0-1.01.0-1.01.0-1.01.00.6-1.01.0-1.0-0.80.8
Locomotion velocity, session 30.20.31.8-0.30.2-0.2-0.2-0.10.1-0.1-0.6-0.20.21.3-0.50.5-0.50.1-0.50.5-0.5-0.80.4-0.20.20.9-0.9
Locomotion distance, session 30.10.10.2-0.50.4-0.4-0.40.2-0.30.3-0.10.2-0.20.4-0.00.0-0.0-0.2-0.00.0-0.00.1-0.0-0.00.00.3-0.3
Stereotopy head waving bouts, day 30.20.20.7-0.60.6-0.6-0.80.4-0.30.3-0.00.3-0.3-0.30.3-0.30.3-0.50.3-0.30.30.3-0.40.8-0.8-0.20.2
Stereotopy head waving duration, day 30.10.10.3-0.40.4-0.4-0.50.2-0.10.1-0.10.2-0.2-0.30.3-0.30.3-0.30.3-0.30.30.2-0.20.6-0.6-0.10.1
Locomotion velocity, session 70.20.21.5-0.60.6-0.6-0.30.9-0.70.71.20.6-0.60.00.3-0.30.3-0.40.3-0.30.30.3-0.30.1-0.1-0.0-0.0
Locomotion distance, session 70.10.20.8-0.40.4-0.4-0.00.7-0.70.70.90.4-0.40.20.1-0.10.1-0.20.1-0.10.10.0-0.1-0.50.50.4-0.4
Stereotopy head waving bouts, day 70.80.91.40.8-0.80.90.7-1.01.1-1.1-0.8-1.01.01.1-1.21.2-1.20.8-1.21.2-1.2-1.00.8-0.40.40.7-0.7
Stereotopy head waving duration, day 71.21.52.31.1-1.11.10.9-1.41.4-1.4-1.1-1.31.31.5-1.51.5-1.51.0-1.51.5-1.5-1.41.0-0.50.50.9-0.8
Locomotion velocity, session 81.41.64.80.9-0.90.91.1-0.91.0-1.0-0.3-1.11.12.2-1.51.5-1.51.1-1.51.5-1.5-1.81.2-1.11.11.3-1.4
Locomotion distance, session 80.30.41.2-1.11.0-1.0-0.90.7-0.70.70.50.4-0.40.80.1-0.10.1-0.30.1-0.10.1-0.20.1-0.20.21.0-1.1
Degree of sensitization distance0.40.41.7-0.50.5-0.5-0.20.9-0.70.71.30.6-0.6-0.90.7-0.70.7-0.50.7-0.70.70.6-0.4-0.00.0-0.20.2
Degree of sensitization stereotypy0.70.71.20.8-0.80.80.6-1.01.0-1.0-0.6-0.90.91.1-1.11.1-1.10.7-1.11.1-1.1-1.00.7-0.30.30.4-0.4
Conditioned locomotion0.10.10.7-0.40.4-0.4-0.30.4-0.30.30.80.3-0.30.20.0-0.00.0-0.30.0-0.00.00.1-0.20.3-0.30.1-0.1
Cocaine response after cond. corrected1.51.72.4-1.51.5-1.5-1.50.9-1.41.40.41.3-1.3-1.51.5-1.51.5-1.31.5-1.51.51.4-1.11.0-0.9-0.60.6
Cocaine response after cond. not corrected2.22.43.9-1.61.7-1.5-1.61.3-1.61.60.81.6-1.5-2.01.8-1.81.8-1.51.8-1.81.81.8-1.41.2-1.1-1.01.0
Cocaine response before conditioning0.10.21.00.2-0.20.20.30.4-0.20.20.40.3-0.3-0.50.3-0.30.3-0.20.3-0.30.30.4-0.50.2-0.2-1.01.0
Saline control response0.20.30.7-0.00.00.0-0.1-0.30.1-0.10.1-0.20.30.7-0.70.7-0.70.4-0.70.7-0.7-0.70.5-0.60.60.9-0.9
Bone: connectivity density1.21.94.00.8-0.80.90.9-1.11.1-1.1-1.9-1.21.22.0-1.41.4-1.41.2-1.41.4-1.4-1.71.5-1.41.41.8-1.8
Bone: cortical apparent density1.72.23.31.3-1.41.41.3-1.41.5-1.5-1.2-1.61.61.7-1.41.4-1.41.6-1.41.4-1.4-1.11.8-1.71.71.8-1.8
Bone: cortical area1.21.74.6-1.51.5-1.5-1.41.9-1.41.42.11.3-1.3-0.61.2-1.21.2-1.41.2-1.21.21.1-1.21.2-1.2-0.70.7
Bone: cortical porosity0.20.21.4-0.40.4-0.3-1.20.10.3-0.30.2-0.10.1-0.80.4-0.40.4-0.10.4-0.40.40.4-0.00.8-0.80.00.0
Bone: cortical porosity0.10.10.70.1-0.10.2-0.7-0.20.8-0.80.0-0.60.6-0.40.1-0.10.10.30.1-0.10.10.10.40.5-0.50.3-0.2
Bone: cortical thickness2.94.79.8-2.62.5-2.6-2.42.8-2.42.43.12.3-2.3-1.12.0-2.02.0-2.32.0-2.02.01.7-2.12.1-2.1-1.31.3
Bone: cortical thickness1.21.34.6-1.71.7-1.6-1.71.8-1.31.32.21.2-1.2-0.60.6-0.60.6-1.10.6-0.60.60.6-0.91.0-1.0-0.10.1
Bone: cortical tissue density1.92.43.61.4-1.41.41.4-1.51.6-1.6-1.3-1.71.71.7-1.41.4-1.41.6-1.41.4-1.4-1.11.8-1.81.81.9-1.9
Condit. Reinf. active minus inactive responses0.20.20.5-0.40.4-0.3-0.10.7-0.60.70.40.6-0.6-0.00.2-0.20.2-0.50.2-0.20.20.0-0.60.2-0.2-0.50.5
Condit. Reinf. active-inactive response ratio0.40.51.2-0.70.7-0.6-0.31.1-0.90.90.60.9-0.9-0.50.6-0.60.6-0.80.6-0.60.60.5-0.80.4-0.4-0.70.7
Condit. Reinf. active responses0.50.61.9-0.50.5-0.5-0.40.7-0.80.80.80.9-0.9-0.60.5-0.50.5-0.80.5-0.50.50.4-1.10.9-0.9-1.41.4
Condit. Reinf. inactive responses0.10.10.50.3-0.30.20.0-0.40.2-0.20.5-0.10.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.2-0.20.5-0.5-0.70.7
Incentive salience index mean0.81.01.7-1.01.0-0.9-0.71.3-1.21.20.91.2-1.2-0.80.7-0.70.7-1.10.7-0.70.70.6-1.20.9-0.9-1.21.2
Condit. Reinf. lever presses0.60.81.6-0.90.9-0.9-0.71.2-1.11.11.01.1-1.1-0.70.5-0.50.5-1.00.5-0.50.50.5-1.21.0-1.0-1.21.2
Condit. Reinf. active minus inactive responses0.20.32.2-0.40.5-0.40.00.9-0.80.81.50.7-0.7-0.00.2-0.20.2-0.50.2-0.20.20.2-0.5-0.00.0-0.30.3
Condit. Reinf. active-inactive response ratio0.20.20.70.2-0.20.30.80.2-0.20.20.60.0-0.00.8-0.50.5-0.50.2-0.50.5-0.5-0.50.2-0.90.90.3-0.3
Condit. Reinf. active responses0.40.52.3-0.80.8-0.7-0.41.2-1.01.01.50.9-0.9-0.20.5-0.50.5-0.80.5-0.50.50.3-0.70.3-0.3-0.50.5
Condit. Reinf. inactive responses1.21.51.8-1.31.3-1.3-1.31.2-1.21.21.11.2-1.2-1.31.4-1.41.4-1.21.4-1.41.41.1-1.21.2-1.2-1.01.0
Condit. Reinf. lever presses0.50.72.41.2-1.21.21.5-1.00.7-0.7-0.9-0.60.61.6-0.70.7-0.70.6-0.70.7-0.7-0.90.3-0.60.5-0.30.3
Condit. Reinf. lever reinforcers received0.30.51.4-0.70.7-0.6-0.30.9-0.90.91.20.9-0.9-0.10.5-0.50.5-0.70.5-0.50.50.3-0.80.4-0.4-0.70.6
Conditioned reinforcement - actives2.02.03.7-1.41.4-1.4-1.21.5-1.51.51.91.5-1.5-1.51.4-1.41.4-1.51.3-1.31.31.4-1.51.2-1.3-1.21.2
Conditioned reinforcement - inactives0.20.30.5-0.70.7-0.7-0.70.5-0.50.50.60.6-0.6-0.40.4-0.40.4-0.60.3-0.30.30.3-0.50.7-0.7-0.30.3
Conditioned locomotion0.10.10.4-0.40.4-0.4-0.10.0-0.60.60.60.4-0.4-0.1-0.40.4-0.4-0.2-0.50.5-0.5-0.1-0.1-0.40.40.3-0.3
Patch foraging indifference point 0 sec0.10.10.30.3-0.30.30.5-0.4-0.10.1-0.00.1-0.2-0.0-0.50.5-0.50.1-0.50.5-0.5-0.4-0.3-0.00.0-0.60.6
Patch foraging indifference point AUC0.00.10.3-0.00.0-0.00.20.1-0.10.10.1-0.10.1-0.20.0-0.00.00.10.0-0.00.0-0.10.3-0.50.50.5-0.5
Delay disc. indifference point, 0s delay0.50.51.20.5-0.50.50.3-1.10.8-0.8-0.6-0.80.80.7-1.01.0-1.00.6-0.70.7-0.7-0.90.7-0.20.20.7-0.6
Delay disc. indifference point, 16s delay1.11.12.0-1.21.2-1.2-1.30.8-1.01.00.71.1-1.1-0.30.8-0.80.8-1.11.0-1.01.00.9-1.11.4-1.4-0.90.9
Delay disc. indifference point, 2s delay0.10.10.40.4-0.40.30.4-0.60.4-0.40.0-0.40.40.4-0.20.2-0.20.3-0.10.1-0.1-0.20.4-0.30.30.3-0.4
Delay disc. indifference point, 24s delay0.10.10.80.5-0.50.40.6-0.20.4-0.40.4-0.20.20.90.1-0.10.10.00.2-0.20.2-0.4-0.10.2-0.2-0.40.4
Delay disc. indifference point, 4s delay0.20.20.70.2-0.20.10.0-0.60.4-0.5-0.1-0.40.40.8-0.50.5-0.50.2-0.50.5-0.5-0.50.30.1-0.10.4-0.4
Delay disc. indifference point, 8s delay0.00.00.10.1-0.10.10.0-0.30.1-0.1-0.1-0.00.00.20.2-0.20.2-0.10.3-0.30.30.1-0.10.3-0.4-0.30.3
Indifference point function ln k0.20.20.6-0.60.6-0.6-0.80.3-0.40.40.30.4-0.4-0.30.5-0.50.5-0.40.5-0.50.50.4-0.40.5-0.5-0.20.2
Indifference point function log k0.20.20.6-0.60.6-0.6-0.80.3-0.40.40.30.4-0.4-0.30.5-0.50.5-0.40.5-0.50.50.4-0.40.5-0.5-0.20.2
Patch foraging total patch changes 0 sec0.10.20.50.4-0.40.30.5-0.50.1-0.1-0.2-0.10.10.3-0.70.7-0.70.3-0.70.7-0.7-0.70.0-0.20.2-0.20.2
Patch foraging total patch changes 12 sec2.53.24.21.9-1.91.82.0-1.91.7-1.7-1.6-1.71.71.6-2.12.1-2.11.8-2.02.0-2.0-2.01.6-1.61.61.1-1.1
Patch foraging total patch changes 18 sec0.00.00.1-0.10.1-0.10.1-0.0-0.30.30.10.2-0.2-0.2-0.10.1-0.1-0.0-0.20.2-0.2-0.1-0.0-0.30.30.1-0.1
Patch foraging total patch changes 24 sec0.30.41.5-0.30.3-0.4-0.30.2-0.60.60.30.7-0.7-0.70.3-0.30.3-0.50.4-0.40.40.6-0.80.7-0.7-1.21.2
Patch foraging total patch changes 6 sec0.00.00.20.1-0.0-0.00.2-0.2-0.20.20.10.2-0.2-0.2-0.20.2-0.2-0.0-0.20.2-0.2-0.4-0.20.0-0.0-0.30.3
Patch foraging time to switch 0 sec2.03.14.92.2-2.22.22.0-2.22.1-2.1-1.8-1.91.91.7-1.81.8-1.81.8-1.81.8-1.8-1.21.5-1.21.20.7-0.6
Patch foraging water rate 0 sec2.03.24.2-2.02.0-2.0-1.92.0-2.02.01.91.9-1.9-1.61.8-1.81.8-1.81.8-1.81.81.2-1.71.5-1.5-1.11.1
Patch foraging water rate 12 sec3.75.77.3-2.62.6-2.6-2.32.6-2.72.72.62.6-2.6-1.72.4-2.42.4-2.52.4-2.42.41.9-2.42.1-2.1-1.81.8
Patch foraging water rate 18 sec0.10.10.5-0.00.0-0.1-0.1-0.20.1-0.10.1-0.10.00.7-0.40.4-0.4-0.0-0.30.3-0.3-0.6-0.00.3-0.3-0.00.0
Patch foraging water rate 24 sec0.20.21.0-0.80.8-0.8-1.00.6-0.50.50.50.4-0.4-0.30.3-0.30.3-0.40.4-0.40.4-0.0-0.20.5-0.50.2-0.2
Patch foraging water rate 6 sec1.52.12.8-1.31.3-1.3-1.31.5-1.41.41.51.5-1.5-1.21.5-1.51.5-1.51.5-1.51.51.1-1.61.7-1.7-1.61.7
Seeking ratio, delayed vs. immediate footshock4.04.66.8-2.62.6-2.5-2.32.5-2.62.62.12.3-2.3-2.22.2-2.22.2-2.12.2-2.22.22.2-1.71.2-1.2-0.70.7
Distance traveled before self-admin1.01.02.3-1.51.5-1.5-1.21.0-1.51.50.81.2-1.2-0.90.7-0.70.7-1.00.8-0.80.80.8-0.80.4-0.3-0.0-0.0
Distance traveled after self-admin2.93.25.8-2.22.2-2.3-1.81.8-2.42.41.62.2-2.2-1.31.6-1.61.6-2.01.5-1.51.51.4-1.91.4-1.4-1.11.1
Extensor digitorum longus weight1.14.28.7-2.92.9-2.8-2.92.3-2.42.41.82.0-2.0-1.72.0-2.02.0-1.92.0-2.02.02.3-1.21.1-1.10.2-0.3
Bone: elastic displacement0.80.91.7-0.90.8-0.8-0.40.9-1.31.30.11.0-1.0-0.91.2-1.21.2-0.71.2-1.21.21.0-0.6-0.30.3-0.20.1
Bone: elastic work0.50.71.6-1.11.1-1.1-0.71.0-1.31.30.51.0-1.0-0.40.9-0.90.9-0.70.9-0.90.90.6-0.5-0.10.20.2-0.2
Bone: endosteal estimation0.30.62.10.7-0.70.90.7-0.70.8-0.7-1.5-0.80.8-0.1-0.60.6-0.60.8-0.60.6-0.6-0.20.9-1.11.10.8-0.8
Bone: endosteal perimeter0.30.71.41.1-1.11.11.0-0.91.0-1.0-1.2-0.90.90.2-0.70.7-0.70.9-0.70.7-0.7-0.40.7-0.70.70.3-0.3
Epididymis fat weight0.20.40.70.7-0.70.70.5-0.70.7-0.7-0.4-0.60.60.7-0.70.7-0.70.4-0.70.7-0.7-0.80.20.1-0.1-0.20.2
Delta time in closed arm before/after self-admin0.70.71.4-1.11.0-1.0-0.81.2-1.11.10.70.7-0.7-1.00.9-0.90.9-0.40.7-0.70.70.8-0.0-0.60.60.8-0.8
Delta time in open arm before/after self-admin0.80.72.11.2-1.11.11.0-1.31.1-1.1-1.4-0.80.80.7-0.80.8-0.80.7-0.80.8-0.8-0.60.4-0.10.1-0.30.3
Diff in mean of infusions in LGA sessions0.30.31.2-0.80.7-0.6-1.10.6-0.0-0.00.3-0.10.1-0.60.3-0.30.3-0.10.4-0.40.40.50.40.0-0.01.1-1.1
Delay discount exponential model param0.10.10.9-0.30.3-0.2-0.10.7-0.50.50.20.4-0.4-0.90.3-0.30.3-0.20.2-0.20.20.5-0.2-0.20.2-0.10.1
Extinction: sum of active levers before priming0.30.32.1-0.50.5-0.4-0.80.00.1-0.1-0.4-0.30.3-0.3-0.30.3-0.30.2-0.10.1-0.10.40.7-0.40.41.4-1.4
Active lever presses in extinction session 61.51.43.6-1.91.9-1.8-1.81.6-1.41.41.11.2-1.2-0.51.0-1.01.0-1.21.0-1.01.00.4-0.80.9-0.90.3-0.3
Bone: final force0.00.00.1-0.10.0-0.1-0.10.20.1-0.10.0-0.10.10.40.3-0.30.30.00.3-0.30.30.00.1-0.10.10.2-0.2
Bone: final moment0.10.10.2-0.30.3-0.3-0.30.4-0.20.20.30.2-0.20.20.4-0.40.4-0.20.4-0.40.40.2-0.10.1-0.10.1-0.1
Food consumed during 24 hour testing period0.10.20.60.2-0.20.10.40.30.0-0.00.60.1-0.10.8-0.30.3-0.3-0.3-0.30.3-0.3-0.5-0.40.6-0.6-0.70.7
Glucose0.20.30.90.4-0.40.40.6-0.50.1-0.1-0.5-0.20.21.0-0.80.8-0.80.5-0.80.8-0.8-0.70.3-0.70.70.3-0.3
Heart weight1.01.41.9-1.41.4-1.3-1.31.4-1.31.31.21.3-1.3-0.81.2-1.21.2-1.31.2-1.21.21.1-1.11.0-1.0-0.70.7
Delay discount hyperbolic model param0.20.20.9-0.40.4-0.3-0.20.8-0.60.60.30.5-0.5-1.00.4-0.40.4-0.30.3-0.30.30.5-0.3-0.10.1-0.20.2
Intermittent access intake day 1-15 change0.90.93.0-0.00.1-0.10.10.8-0.60.60.70.7-0.8-1.01.1-1.11.1-0.71.2-1.21.20.7-1.10.8-0.8-1.71.7
Intermittent access intake escalation1.21.24.1-0.10.1-0.20.20.8-0.80.80.60.9-1.0-0.91.3-1.31.3-0.91.4-1.41.41.0-1.30.8-0.9-2.02.0
Intermittent access intake escalation 20.20.21.10.9-0.90.91.0-0.40.5-0.5-0.1-0.30.30.4-0.20.2-0.20.3-0.10.1-0.1-0.30.0-0.20.2-0.70.7
Intermitt. access day 1 inactive lever presses3.74.07.5-2.12.1-2.0-2.12.1-1.91.90.81.8-1.8-2.72.4-2.42.4-1.72.3-2.32.32.6-1.51.3-1.3-1.00.9
Intermitt. access day 15 inactive lever presses0.40.41.0-0.90.8-0.7-1.00.8-0.50.50.30.5-0.5-0.60.8-0.80.8-0.50.7-0.70.70.6-0.30.5-0.50.0-0.0
Intermitt. access escalation Index0.30.20.8-0.00.0-0.1-0.00.2-0.10.10.10.3-0.3-0.60.6-0.60.6-0.40.6-0.60.60.7-0.50.7-0.7-0.90.9
Intermittent access day 1 total infusions0.20.31.7-0.70.7-0.7-0.70.6-0.40.41.30.4-0.40.10.1-0.10.1-0.60.0-0.00.00.4-0.40.6-0.60.0-0.0
Intermittent access day 15 total infusions0.91.12.4-0.60.6-0.7-0.41.1-0.90.91.51.0-1.0-0.81.1-1.11.1-1.01.1-1.11.10.9-1.21.0-1.0-1.31.3
Intermittent access terminal intake (last 3 days)0.20.22.0-0.20.2-0.20.00.6-0.40.41.40.4-0.4-0.20.4-0.40.4-0.50.3-0.30.30.5-0.50.3-0.3-0.50.5
Intermittent access total infusions0.30.32.8-0.40.4-0.4-0.30.7-0.50.41.70.5-0.5-0.30.3-0.30.3-0.50.2-0.20.20.5-0.50.5-0.5-0.40.4
Intermittent access day 1 locomotion0.10.10.3-0.50.5-0.5-0.50.3-0.30.30.50.4-0.4-0.20.2-0.20.2-0.50.1-0.10.10.3-0.40.6-0.6-0.30.3
Intermittent access day 15 total locomotion0.10.10.20.4-0.40.40.5-0.20.2-0.20.3-0.10.1-0.0-0.20.2-0.20.1-0.30.3-0.3-0.2-0.1-0.00.0-0.40.4
Intermittent access total locomotion0.10.10.2-0.10.1-0.1-0.10.2-0.10.10.40.2-0.2-0.30.2-0.20.2-0.30.1-0.10.10.2-0.30.4-0.4-0.40.4
Intermittent access standard deviation2.62.73.5-1.51.5-1.6-1.21.5-1.91.91.31.8-1.9-1.31.8-1.81.8-1.81.7-1.71.71.6-1.81.5-1.5-1.71.6
Left kidney weight8.022.432.6-5.75.7-5.7-5.45.1-5.45.44.65.0-5.0-4.54.8-4.84.8-4.74.7-4.74.74.5-4.23.8-3.8-2.32.3
Right kidney weight5.013.921.1-4.64.6-4.6-4.53.9-4.24.23.74.0-3.9-3.53.6-3.63.6-3.83.6-3.63.63.5-3.33.3-3.2-1.81.8
Cocaine induced anxiety0.20.20.80.6-0.60.60.9-0.50.3-0.3-0.4-0.20.20.1-0.50.5-0.50.3-0.50.5-0.5-0.50.1-0.40.4-0.30.3
Post-drug Anxiety0.40.41.20.7-0.70.70.8-0.70.6-0.6-1.1-0.60.60.3-0.60.6-0.60.6-0.60.6-0.6-0.70.6-0.80.80.4-0.4
Baseline Anxiety0.91.02.5-1.31.3-1.3-1.61.0-0.90.90.10.8-0.8-1.31.1-1.11.1-0.81.1-1.11.11.1-0.50.7-0.7-0.00.0
Tail length0.51.41.81.1-1.11.20.9-0.91.3-1.3-1.2-1.31.31.0-1.31.3-1.31.3-1.31.3-1.3-1.11.2-1.01.01.1-1.0
Length with tail0.00.10.2-0.10.1-0.1-0.30.20.1-0.1-0.0-0.10.10.1-0.40.4-0.40.1-0.40.4-0.4-0.30.10.1-0.10.2-0.2
Length without tail0.51.12.8-1.41.4-1.4-1.71.0-1.01.01.01.1-1.0-0.90.8-0.80.8-1.00.8-0.80.80.7-1.01.3-1.3-0.50.5
Times rat made contact with spout0.40.51.0-0.90.9-0.9-1.00.1-0.80.8-0.80.7-0.7-0.90.6-0.60.6-0.70.6-0.60.60.8-0.60.5-0.5-0.20.2
Lifetime Intake0.30.43.2-0.50.5-0.5-0.40.7-0.50.51.80.6-0.6-0.40.3-0.30.3-0.60.2-0.20.20.4-0.60.6-0.6-0.60.6
Liver weight, left0.71.22.7-1.41.4-1.3-1.21.6-1.31.21.31.2-1.2-0.80.9-0.90.9-1.10.9-0.90.90.8-1.00.9-0.9-0.40.4
Liver weight, right0.20.31.1-0.90.8-0.8-1.10.6-0.40.30.20.3-0.2-0.80.3-0.30.3-0.30.3-0.30.30.40.10.2-0.20.7-0.7
Locomotor activity0.00.00.2-0.00.0-0.00.2-0.0-0.30.3-0.10.2-0.20.1-0.00.0-0.00.1-0.00.0-0.00.3-0.0-0.40.4-0.00.0
Locomotor testing distance0.10.20.8-0.20.2-0.20.30.4-0.90.90.10.6-0.7-0.20.3-0.30.3-0.20.2-0.20.20.4-0.3-0.60.6-0.30.3
Locomotor testing rearing0.10.20.60.1-0.10.10.5-0.1-0.30.3-0.30.1-0.10.4-0.60.6-0.60.3-0.60.6-0.6-0.50.1-0.80.80.2-0.3
Locomotion in novel chamber2.32.83.4-1.81.8-1.8-1.71.4-1.71.71.11.8-1.8-1.41.7-1.71.7-1.81.7-1.71.71.8-1.81.8-1.8-1.41.4
Locomotion in novel chamber post-restriction0.81.01.9-1.41.3-1.4-1.41.0-1.01.00.70.9-0.9-0.40.9-0.90.9-1.11.0-1.01.01.1-0.81.0-1.0-0.10.1
Fecal boli incidents, locomotor time 10.10.10.3-0.20.2-0.2-0.50.20.0-0.00.50.00.0-0.20.3-0.30.3-0.10.5-0.50.50.40.00.1-0.10.1-0.1
Change in fecal boli incidents, locomotor task0.90.91.20.9-0.90.90.8-1.01.0-1.1-0.7-1.01.00.6-1.11.1-1.10.9-1.11.1-1.1-1.10.9-0.60.60.7-0.7
Time >=10cm from walls, locomotor time 11.01.02.40.5-0.50.60.6-0.90.7-0.6-1.1-0.90.90.9-1.01.0-1.01.0-1.01.0-1.0-0.91.2-1.31.31.5-1.5
Bouts of movement, locomotor time 11.11.23.60.7-0.70.70.2-1.51.2-1.3-1.9-1.21.21.3-1.01.0-1.01.1-1.11.1-1.1-1.01.2-0.60.71.3-1.3
Total resting periods, locomotor time 10.90.93.10.7-0.70.70.1-1.41.2-1.2-1.8-1.11.21.0-0.80.8-0.81.0-0.90.9-0.9-0.71.1-0.50.51.0-1.0
Rest time, locomotor task time 10.40.50.70.8-0.80.90.7-0.70.8-0.8-0.8-0.70.70.4-0.80.8-0.80.8-0.70.7-0.7-0.40.6-0.60.60.2-0.2
Distance moved, locomotor task time 10.20.20.6-0.60.5-0.6-0.30.8-0.60.60.80.5-0.50.20.4-0.40.4-0.60.2-0.20.2-0.3-0.40.2-0.2-0.0-0.0
Vertical activity count, locomotor time 11.11.11.9-1.11.1-1.2-1.01.3-1.11.11.41.1-1.1-0.91.2-1.21.2-1.21.1-1.11.10.8-1.00.9-0.9-0.60.6
Time >=10cm from walls, locomotor time 20.10.10.5-0.50.5-0.4-0.30.2-0.30.30.40.2-0.20.1-0.00.0-0.0-0.0-0.10.1-0.1-0.20.1-0.30.30.7-0.7
Bouts of movement, locomotor time 20.20.31.10.2-0.20.20.2-0.70.5-0.5-1.1-0.50.51.0-0.30.3-0.30.4-0.30.3-0.3-0.60.5-0.30.30.7-0.7
Total resting periods, locomotor time 20.30.31.70.4-0.40.40.3-0.80.5-0.5-1.3-0.50.51.0-0.40.4-0.40.5-0.30.3-0.3-0.60.5-0.30.30.6-0.6
Rest time, locomotor task time 20.30.31.00.9-0.90.80.7-0.80.7-0.7-1.0-0.50.5-0.1-0.20.2-0.20.6-0.00.0-0.00.10.3-0.20.1-0.40.4
Distance moved, locomotor task time 21.01.23.1-1.31.3-1.3-0.81.8-1.51.51.61.3-1.4-0.50.9-0.90.9-1.30.8-0.80.80.6-1.10.7-0.7-0.60.6
Vertical activity count, locomotor time 22.02.24.1-1.91.9-1.9-1.52.0-1.91.91.81.7-1.7-0.91.5-1.51.5-1.71.2-1.21.20.8-1.31.0-0.9-0.50.5
Light reinforcement 10.10.31.2-0.70.7-0.6-0.70.5-0.60.60.40.6-0.6-1.10.1-0.10.1-0.50.3-0.30.30.7-0.50.5-0.5-0.20.2
Light reinforcement 21.41.83.1-1.71.7-1.8-1.71.3-1.71.61.41.5-1.5-1.31.0-1.01.0-1.51.1-1.11.11.4-1.31.3-1.3-0.80.8
Bone: marrow area0.20.52.10.6-0.60.80.6-0.60.7-0.6-1.5-0.70.7-0.1-0.50.5-0.50.7-0.50.5-0.5-0.10.8-1.01.00.7-0.7
Bone: maximum diameter0.10.20.5-0.30.3-0.3-0.40.6-0.20.20.70.3-0.3-0.10.4-0.40.4-0.50.4-0.40.40.4-0.40.6-0.6-0.50.5
Bone: maximum force0.00.00.2-0.20.2-0.2-0.10.4-0.10.10.10.0-0.00.30.0-0.00.0-0.00.0-0.00.0-0.00.1-0.20.20.4-0.4
Bone: maximum moment0.10.10.4-0.50.4-0.4-0.40.6-0.40.40.40.3-0.30.10.2-0.20.2-0.20.2-0.20.20.1-0.1-0.00.00.3-0.3
Mean time between licks in bursts1.82.65.91.3-1.31.21.4-1.21.3-1.3-0.4-1.41.42.4-1.81.8-1.81.5-1.81.8-1.8-2.21.5-1.61.61.7-1.7
Mean num. licks in bursts0.10.10.2-0.40.4-0.3-0.30.1-0.30.4-0.40.2-0.2-0.00.0-0.00.0-0.00.0-0.00.0-0.10.1-0.30.30.5-0.5
Cd content in liver0.20.20.90.2-0.20.3-0.0-0.50.4-0.4-0.1-0.50.5-0.1-0.20.2-0.20.6-0.20.2-0.2-0.00.8-0.80.80.9-0.9
Co content in liver0.50.62.00.3-0.30.40.6-0.60.3-0.3-0.9-0.60.50.6-0.60.6-0.60.6-0.60.6-0.6-0.60.9-1.31.31.4-1.4
Cu content in liver0.20.31.10.5-0.50.50.8-0.60.1-0.1-0.4-0.30.30.3-0.40.4-0.40.6-0.40.4-0.4-0.70.5-1.11.10.5-0.5
Fe content in liver1.41.63.1-1.41.4-1.3-1.61.2-1.21.21.01.2-1.2-1.81.3-1.31.3-1.21.3-1.31.31.6-1.11.1-1.1-0.80.8
K content in liver0.70.71.21.0-1.00.91.0-1.10.7-0.7-0.5-0.80.80.9-0.80.8-0.80.8-0.80.8-0.8-1.00.7-0.80.80.4-0.4
Mg content in liver0.30.31.70.7-0.70.60.7-0.20.3-0.31.0-0.0-0.0-0.10.2-0.20.2-0.10.2-0.20.2-0.2-0.50.5-0.5-1.31.3
Mn content in liver0.00.00.20.2-0.20.20.4-0.20.1-0.10.4-0.10.10.2-0.20.2-0.20.2-0.20.2-0.2-0.10.2-0.30.30.2-0.2
Na content in liver0.50.61.00.5-0.50.50.6-0.40.6-0.6-0.1-0.70.70.9-0.90.9-0.90.7-0.90.9-0.9-1.00.8-0.80.80.9-0.9
Rb content in liver0.00.00.20.2-0.20.10.0-0.30.2-0.2-0.1-0.20.20.4-0.20.2-0.20.2-0.20.2-0.2-0.10.2-0.00.00.2-0.1
Se content in liver0.10.20.7-0.00.00.0-0.1-0.20.0-0.00.1-0.10.10.6-0.60.6-0.60.3-0.60.6-0.6-0.80.2-0.30.30.4-0.4
Sr content in liver0.10.10.3-0.20.2-0.1-0.2-0.2-0.20.2-0.30.2-0.2-0.60.4-0.40.4-0.10.4-0.40.40.2-0.0-0.20.20.1-0.1
Zn content in liver0.80.81.51.2-1.11.11.2-1.00.9-0.8-0.3-0.80.80.6-1.11.1-1.10.9-1.11.1-1.1-1.10.5-0.60.6-0.00.0
Bone: minimum diameter0.20.41.3-0.80.7-0.7-0.70.8-0.70.70.50.5-0.5-1.20.6-0.60.6-0.40.6-0.60.61.1-0.2-0.10.10.2-0.3
Time in familiar zone, hab. session 10.10.10.30.1-0.10.10.60.1-0.40.40.50.3-0.30.4-0.00.0-0.0-0.1-0.00.0-0.0-0.0-0.2-0.30.3-0.40.3
Time in novel zone, hab. session 10.60.61.90.4-0.40.50.1-0.60.7-0.7-1.4-0.80.80.4-0.50.5-0.50.8-0.50.5-0.5-0.71.0-0.90.91.3-1.3
Total zone transitions, hab. session 10.10.10.5-0.50.5-0.5-0.70.0-0.10.1-0.50.00.00.30.2-0.20.20.00.2-0.20.20.00.2-0.00.00.7-0.7
Total locomotion distance, hab. session 10.60.81.1-1.01.0-1.0-1.00.8-0.90.90.40.9-0.9-0.71.1-1.11.1-0.91.1-1.11.10.9-0.80.8-0.8-0.60.6
Locomotion velocity, hab. session 10.20.30.7-0.60.6-0.6-0.70.3-0.40.40.10.5-0.5-0.30.7-0.70.7-0.50.7-0.70.70.5-0.60.8-0.8-0.50.5
Time in familiar zone, hab. session 20.10.10.50.3-0.30.20.7-0.4-0.10.10.2-0.00.00.3-0.20.2-0.20.2-0.20.2-0.2-0.40.2-0.70.70.2-0.3
Time in novel zone, hab. session 20.10.10.80.1-0.10.2-0.1-0.10.3-0.3-0.9-0.30.30.6-0.40.4-0.40.3-0.40.4-0.4-0.40.3-0.10.20.4-0.4
Total zone transitions, hab. session 20.10.20.8-0.70.6-0.6-0.70.2-0.40.3-0.40.2-0.20.90.2-0.20.2-0.20.2-0.20.2-0.30.00.1-0.10.6-0.6
Total locomotion distance, hab. session 20.71.01.6-1.21.2-1.3-1.10.9-1.21.20.51.1-1.10.01.0-1.01.0-1.01.0-1.01.00.7-1.01.0-1.0-0.70.6
Locomotion velocity, hab. session 21.11.52.3-1.51.5-1.5-1.41.2-1.41.40.71.3-1.3-0.31.3-1.31.3-1.31.3-1.31.31.0-1.31.3-1.3-0.80.8
Novel to familiar place preference ratio0.40.41.4-0.30.3-0.4-0.30.6-0.60.60.70.7-0.7-0.90.4-0.40.4-0.50.4-0.40.40.6-0.80.8-0.8-1.21.2
Novelty place preference0.20.20.8-0.20.2-0.2-0.30.4-0.40.40.50.5-0.5-0.70.2-0.20.2-0.30.2-0.20.20.3-0.60.6-0.6-0.90.9
Time in novel zone, NPP test0.10.10.5-0.10.1-0.1-0.20.2-0.30.30.20.3-0.3-0.4-0.00.0-0.0-0.1-0.00.0-0.00.1-0.40.3-0.4-0.70.7
Total zone transitions, NPP test0.71.02.5-1.61.5-1.5-1.61.1-1.21.20.51.1-1.1-0.21.0-1.01.0-1.01.0-1.01.00.7-0.70.8-0.80.0-0.0
Total locomotion distance, NPP test1.31.82.6-1.61.6-1.6-1.51.3-1.61.60.81.5-1.5-0.71.3-1.31.3-1.41.3-1.31.31.0-1.41.3-1.3-0.90.9
Locomotion velocity, NPP test2.02.83.7-1.91.9-1.9-1.71.8-1.91.91.31.8-1.8-1.11.7-1.71.7-1.81.7-1.71.71.4-1.71.6-1.6-1.21.2
Intraocular pressure0.10.10.70.2-0.20.20.1-0.20.1-0.10.10.1-0.1-0.20.1-0.10.1-0.10.2-0.20.20.4-0.40.5-0.5-0.80.9
Delta distance traveled before/after self-admin1.21.22.5-1.01.0-1.0-0.81.0-1.11.11.01.3-1.3-0.41.0-1.01.0-1.30.7-0.70.70.6-1.51.5-1.5-1.61.6
Delta ambulatory time before/after self-admin0.60.71.7-0.60.7-0.7-0.50.6-0.80.80.70.9-0.90.20.7-0.70.7-1.00.3-0.30.30.0-1.21.3-1.3-1.31.3
Parametrial fat weight0.10.30.50.3-0.30.40.1-0.40.6-0.6-0.6-0.60.60.5-0.40.4-0.40.6-0.40.4-0.4-0.70.6-0.50.50.7-0.7
Pavlov. Cond. lever latency2.02.53.81.9-1.91.92.0-1.81.7-1.7-1.2-1.61.61.9-1.41.4-1.41.7-1.41.4-1.4-1.51.5-1.61.60.9-0.9
Pavlov. Cond. magazine entry latency0.50.71.10.7-0.70.80.6-0.70.9-0.9-1.0-0.90.90.6-0.70.7-0.70.8-0.70.7-0.7-0.71.0-0.90.91.0-1.0
Pavlov. Cond. change in total contacts0.00.00.2-0.20.2-0.1-0.20.4-0.10.10.30.1-0.10.0-0.20.2-0.2-0.1-0.20.2-0.2-0.4-0.10.3-0.2-0.10.1
Pavlov. Cond. index score0.30.40.8-0.80.8-0.8-0.90.9-0.60.60.20.6-0.6-0.90.6-0.60.6-0.70.6-0.60.60.6-0.40.5-0.5-0.10.1
Pavlov. Cond. latency score0.40.61.2-1.01.0-0.9-1.00.9-0.70.70.30.7-0.6-1.10.8-0.80.8-0.80.8-0.80.80.7-0.50.7-0.7-0.20.2
Pavlov. Cond. lever contacts1.72.03.1-1.61.6-1.6-1.71.5-1.41.40.81.4-1.4-1.81.4-1.41.4-1.41.4-1.41.41.5-1.31.4-1.4-0.80.8
Pavlov. Cond. magazine entry number0.20.30.8-0.30.3-0.4-0.20.4-0.60.60.90.6-0.6-0.30.4-0.40.4-0.40.4-0.40.40.3-0.70.5-0.5-0.80.8
Pavlov. Cond. intertrial magazine entries0.81.03.6-0.20.3-0.3-0.30.3-0.60.60.70.8-0.8-1.00.9-0.90.9-0.80.9-0.90.91.1-1.21.3-1.3-1.91.9
Pavlov. Cond. lever-magazine prob. diff.0.40.40.7-0.80.8-0.7-0.80.9-0.60.60.20.6-0.6-0.90.7-0.70.7-0.70.7-0.70.70.6-0.50.6-0.6-0.30.3
Pavlov. Cond. response bias0.10.20.6-0.60.6-0.6-0.80.5-0.40.4-0.20.3-0.3-0.60.3-0.30.3-0.30.3-0.30.30.4-0.00.1-0.10.3-0.3
Pavlov. Cond. lever latency0.40.52.1-1.11.1-1.0-1.40.8-0.50.50.60.4-0.4-1.40.4-0.40.4-0.40.4-0.40.40.70.00.2-0.20.8-0.8
Pavlov. Cond. magazine entry latency2.22.65.52.0-2.02.02.4-1.81.4-1.4-2.1-1.41.42.1-1.51.5-1.51.4-1.51.5-1.5-1.71.1-1.51.40.4-0.4
Pavlov. Cond. change in total contacts0.60.82.71.4-1.31.31.7-0.70.7-0.7-0.6-0.50.51.6-0.70.7-0.70.5-0.70.7-0.7-0.80.0-0.20.2-0.90.9
Pavlov. Cond. index score1.31.74.21.7-1.71.72.1-1.61.1-1.1-1.7-1.01.02.0-1.21.2-1.21.0-1.21.2-1.2-1.20.6-0.90.9-0.20.2
Pavlov. Cond. latency score1.11.33.51.5-1.51.51.9-1.40.9-0.9-1.5-0.80.81.9-1.01.0-1.00.8-1.01.0-1.0-1.20.5-0.80.7-0.30.3
Pavlov. Cond. lever contacts0.40.52.11.1-1.01.01.3-0.90.5-0.5-1.0-0.30.31.4-0.40.4-0.40.4-0.40.4-0.4-0.6-0.0-0.20.2-0.80.9
Pavlov. Cond. magazine entry number2.02.44.1-1.81.8-1.8-2.01.8-1.61.61.91.5-1.5-2.01.5-1.51.5-1.41.5-1.51.51.6-1.31.4-1.4-0.80.8
Pavlov. Cond. intertrial magazine entries0.10.10.7-0.00.0-0.0-0.20.20.1-0.10.8-0.10.10.3-0.50.5-0.50.2-0.50.5-0.5-0.20.20.1-0.10.3-0.2
Pavlov. Cond. lever-magazine prob. diff.1.52.04.81.9-1.81.82.2-1.71.2-1.2-1.8-1.11.12.1-1.31.3-1.31.1-1.31.3-1.3-1.30.7-1.11.0-0.20.1
Pavlov. Cond. response bias1.01.43.91.6-1.61.51.8-1.51.1-1.1-1.5-1.01.02.0-1.01.0-1.00.9-1.01.0-1.0-1.20.6-0.80.8-0.20.2
Time in closed arm before self-admin1.01.12.31.3-1.31.21.4-1.31.0-1.0-0.8-0.90.91.2-1.21.2-1.20.8-1.11.1-1.1-1.50.5-0.40.4-0.10.2
Time in closed arm after self-admin0.20.20.60.4-0.40.40.6-0.40.3-0.3-0.1-0.30.30.6-0.40.4-0.40.5-0.50.5-0.5-0.80.4-0.60.60.4-0.4
Time in open arm before self-admin0.30.30.9-0.60.6-0.5-0.60.8-0.50.50.30.3-0.3-0.70.8-0.80.8-0.20.7-0.70.70.90.0-0.20.20.4-0.4
Time in open arm after self-admin0.00.00.2-0.20.2-0.1-0.4-0.10.1-0.1-0.4-0.00.1-0.20.0-0.00.0-0.00.1-0.10.10.40.10.1-0.10.2-0.2
Bone: periosteal estimation0.10.20.8-0.60.6-0.5-0.60.9-0.50.50.50.5-0.5-0.50.5-0.50.5-0.50.5-0.50.50.7-0.30.2-0.2-0.00.0
Bone: periosteal perimeter0.10.10.4-0.20.2-0.1-0.20.6-0.20.20.50.3-0.2-0.30.4-0.40.4-0.30.4-0.40.40.6-0.30.2-0.2-0.30.3
Bone: post-yield work0.30.41.50.6-0.60.70.7-0.60.6-0.6-1.2-0.60.60.4-0.80.8-0.80.6-0.80.8-0.8-0.40.6-0.60.60.4-0.4
Progressive ratio test 1 active lever presses0.10.10.2-0.30.3-0.3-0.20.3-0.20.20.40.3-0.3-0.10.3-0.30.3-0.40.2-0.20.20.2-0.40.5-0.5-0.30.3
Progressive ratio test 1 breakpoint0.20.20.5-0.40.4-0.4-0.40.5-0.40.40.70.5-0.5-0.20.4-0.40.4-0.50.3-0.30.30.3-0.50.6-0.6-0.40.4
Progressive ratio test 1 inactive lever presses0.50.60.9-0.90.9-0.9-0.80.8-0.90.90.30.8-0.8-0.60.8-0.80.8-0.80.7-0.70.70.7-0.70.6-0.6-0.40.4
Progressive ratio test 2 active lever presses0.80.83.1-0.50.5-0.5-0.31.0-0.80.81.80.9-1.0-0.80.7-0.70.7-1.00.7-0.70.70.8-1.11.0-1.0-1.31.3
Progressive ratio test 2 breakpoint0.50.52.9-0.40.4-0.4-0.20.8-0.60.61.70.7-0.7-0.70.5-0.50.5-0.80.5-0.50.50.5-0.90.8-0.8-1.01.0
Progressive ratio test 2 inactive lever presses1.31.53.1-0.90.9-0.9-0.71.1-1.11.11.81.3-1.3-1.11.0-1.01.0-1.31.0-1.01.01.2-1.51.4-1.4-1.71.7
Incentive Sensitization - Responses0.30.31.40.7-0.60.60.70.00.4-0.41.2-0.10.10.1-0.10.1-0.1-0.1-0.20.2-0.2-0.1-0.30.5-0.5-1.01.1
Incentive Sensitization - Breakpoint0.20.21.40.6-0.60.60.60.10.3-0.31.2-0.10.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.1-0.40.5-0.5-1.01.1
Sum of active levers in priming session hrs 5-60.40.30.9-0.80.8-0.7-0.70.8-0.50.5-0.30.2-0.2-0.00.7-0.70.7-0.30.6-0.60.60.20.2-0.30.30.9-1.0
Progressive ratio0.70.81.5-0.40.4-0.5-0.40.5-0.50.50.50.7-0.7-0.81.2-1.21.2-0.81.0-1.01.00.8-1.01.2-1.2-1.21.2
Food seeking constrained by brief footshock2.63.24.61.7-1.71.81.5-1.61.9-1.9-1.8-2.02.01.8-1.61.6-1.62.0-1.41.4-1.4-1.62.1-2.12.12.1-2.1
Seeking ratio, punishment vs. effort3.34.16.81.6-1.61.71.6-1.61.7-1.7-1.8-1.91.92.0-2.22.2-2.22.1-2.02.0-2.0-1.92.3-2.62.62.4-2.4
Retroperitoneal fat weight0.31.11.71.2-1.21.11.2-1.31.0-1.0-0.9-0.90.91.2-1.31.3-1.31.0-1.21.2-1.2-1.30.7-0.50.50.2-0.2
Reaction time number correct0.00.00.10.1-0.10.20.10.30.3-0.3-0.0-0.20.3-0.2-0.00.0-0.00.20.0-0.00.0-0.10.2-0.10.10.2-0.2
Reaction time mean minus median0.20.30.70.8-0.80.80.8-0.50.8-0.8-0.4-0.70.70.5-0.10.1-0.10.4-0.10.1-0.1-0.10.4-0.20.20.0-0.0
Reaction time mean minus median AUC0.10.10.40.6-0.60.60.5-0.30.6-0.6-0.4-0.50.50.20.0-0.00.00.30.1-0.10.10.00.4-0.30.30.2-0.2
Reaction time num false alarms1.01.31.9-1.11.2-1.1-1.01.2-1.21.21.41.2-1.2-0.41.1-1.11.1-1.21.1-1.11.10.9-1.31.4-1.4-1.21.2
Reaction time num false alarms AUC1.52.02.6-1.51.5-1.5-1.41.5-1.51.51.61.6-1.6-0.71.3-1.31.3-1.51.4-1.41.41.1-1.61.6-1.6-1.31.3
Reaction time trials correct on left0.00.00.10.1-0.10.20.10.30.3-0.3-0.0-0.20.3-0.2-0.00.0-0.00.20.0-0.00.0-0.10.2-0.10.10.2-0.2
Reaction time trials on left0.00.00.10.2-0.10.20.10.30.3-0.3-0.0-0.30.3-0.2-0.00.0-0.00.20.0-0.00.0-0.10.2-0.10.10.2-0.2
Reaction time mean0.30.41.20.9-0.90.80.5-0.91.1-1.1-0.7-0.90.90.4-0.40.4-0.40.6-0.40.4-0.4-0.10.6-0.10.10.2-0.2
Reaction time mean AUC0.40.61.40.9-0.90.90.6-1.01.2-1.2-0.8-1.01.10.5-0.60.6-0.60.8-0.60.6-0.6-0.30.8-0.40.40.6-0.6
Median of all reaction times0.40.61.61.0-1.01.00.6-1.11.2-1.3-0.8-1.01.00.5-0.60.6-0.60.8-0.70.7-0.7-0.30.7-0.10.10.2-0.2
Reaction time omissions0.10.10.30.0-0.00.1-0.4-0.10.5-0.6-0.1-0.40.4-0.0-0.00.0-0.00.1-0.00.0-0.00.10.20.4-0.40.2-0.2
Reaction time false alarm rate1.52.12.8-1.61.6-1.6-1.41.3-1.71.71.61.7-1.7-0.61.3-1.31.3-1.61.4-1.41.41.2-1.61.5-1.5-1.41.4
Reaction time premature initiation rate0.30.41.10.9-0.90.81.0-0.70.4-0.4-0.7-0.40.40.9-0.60.6-0.60.6-0.60.6-0.6-0.40.3-0.60.6-0.20.2
Reaction time premature initiations0.50.71.61.1-1.11.11.3-0.80.8-0.8-0.9-0.80.80.9-0.80.8-0.80.9-0.80.8-0.8-0.70.6-0.80.80.1-0.1
Std. dev. reaction times0.10.20.50.6-0.60.60.6-0.50.7-0.7-0.4-0.60.60.6-0.20.2-0.20.4-0.20.2-0.2-0.20.5-0.20.20.2-0.2
Reaction time trials completed0.00.00.10.2-0.10.20.10.30.3-0.3-0.0-0.30.3-0.2-0.00.0-0.00.20.0-0.00.0-0.10.2-0.10.10.2-0.2
Reaction time trials AUC0.00.00.20.0-0.00.1-0.00.40.1-0.10.1-0.10.1-0.40.1-0.10.10.00.2-0.20.2-0.00.10.0-0.00.1-0.1
Run reversals in cocaine runway, females0.80.82.40.9-0.90.80.5-1.51.0-1.0-1.1-0.80.80.9-1.11.1-1.10.8-1.21.2-1.2-1.10.5-0.00.00.1-0.0
Run reversals in cocaine runway, males2.22.13.4-1.31.3-1.3-1.01.2-1.61.60.41.5-1.5-1.21.8-1.81.8-1.51.8-1.81.81.8-1.41.1-1.1-1.31.3
Latency to leave start box in cocaine runway0.60.61.0-0.80.8-0.7-0.70.9-0.70.70.60.8-0.8-0.60.8-0.80.8-0.91.0-1.01.00.8-0.80.9-0.9-0.70.7
Latency to leave start box in cocaine runway, F1.71.82.7-1.21.2-1.1-1.11.6-1.11.11.01.3-1.2-1.41.6-1.61.6-1.41.6-1.61.61.4-1.31.3-1.3-1.31.3
Latency to leave start box in cocaine runway, M0.10.10.30.1-0.10.00.0-0.40.2-0.2-0.5-0.20.20.3-0.30.3-0.30.3-0.10.1-0.1-0.20.3-0.30.30.5-0.5
Std. dev. time between licks in bursts2.83.46.01.8-1.81.71.9-1.71.8-1.8-0.8-1.81.82.5-2.12.1-2.11.8-2.12.1-2.1-2.41.6-1.51.51.4-1.4
Total sessions with >9 infusions0.70.81.51.1-1.11.01.1-0.90.9-0.90.2-0.80.80.9-1.11.1-1.10.7-1.11.1-1.1-1.20.5-0.40.40.1-0.1
Short access day 1 total inactive lever presses5.46.17.5-2.22.2-2.3-2.02.4-2.52.52.32.6-2.6-2.72.5-2.52.5-2.52.5-2.52.52.4-2.62.4-2.4-2.62.5
Short access day 10 total inactive lever presses3.33.76.3-2.42.4-2.3-2.51.9-2.02.00.51.9-1.9-2.22.1-2.12.1-1.82.1-2.12.12.2-1.51.4-1.4-0.70.7
Short access day 1 total infusions0.30.32.2-0.30.3-0.3-0.60.6-0.20.21.50.4-0.4-0.80.4-0.40.4-0.50.3-0.30.30.5-0.60.8-0.8-0.80.8
Short access day 10 total infusions0.20.20.8-0.50.5-0.5-0.40.5-0.50.50.90.5-0.50.00.4-0.40.4-0.60.3-0.30.30.2-0.50.6-0.6-0.40.4
Short access total infusions0.20.32.5-0.40.4-0.4-0.50.6-0.30.31.60.4-0.4-0.30.1-0.10.1-0.50.0-0.00.00.2-0.50.7-0.7-0.50.5
Short access day 1 locomotion0.50.51.2-0.40.5-0.5-0.40.5-0.70.71.00.8-0.8-0.80.6-0.60.6-0.80.7-0.70.70.6-0.90.8-0.8-1.11.1
Short access day 10 total locomotion0.91.01.6-0.90.9-0.9-0.90.7-0.90.9-0.31.0-1.0-0.71.2-1.21.2-1.11.2-1.21.20.9-1.11.2-1.2-1.01.0
Short access total locomotion0.00.00.10.2-0.20.10.3-0.2-0.00.0-0.10.0-0.00.1-0.20.2-0.20.0-0.10.1-0.1-0.2-0.0-0.10.1-0.10.1
One hour access (0.3 mA shock)0.40.51.21.1-1.01.01.1-0.60.9-0.90.2-0.70.70.8-0.70.7-0.70.7-0.60.6-0.6-0.30.5-0.50.50.0-0.0
Compulsive drug intake0.20.21.00.2-0.20.3-0.0-0.30.5-0.5-1.0-0.50.50.3-0.30.3-0.30.5-0.20.2-0.2-0.00.7-0.60.60.8-0.8
One hour access (shock baseline)0.20.21.20.3-0.30.20.60.1-0.20.21.10.3-0.30.00.1-0.10.1-0.30.1-0.10.10.1-0.50.2-0.2-0.90.9
Social response proportion0.91.02.01.4-1.31.21.4-1.21.0-1.0-0.9-1.00.90.7-1.01.0-1.01.0-0.90.9-0.9-0.90.7-0.80.80.2-0.2
Social responses0.81.12.51.4-1.31.31.6-1.11.0-1.0-0.9-1.01.00.9-1.11.1-1.11.0-0.90.9-0.9-1.10.8-1.00.90.3-0.3
Social time0.40.51.2-1.11.1-1.0-1.01.1-0.90.90.80.8-0.8-0.50.6-0.60.6-0.70.5-0.50.50.5-0.60.5-0.5-0.00.0
Soleus weight2.47.110.4-2.02.0-2.0-1.23.2-2.92.92.82.9-3.0-2.12.8-2.82.8-2.82.8-2.82.83.0-3.02.1-2.1-3.23.2
Bone: stiffness0.10.10.40.1-0.10.1-0.10.20.3-0.30.6-0.30.30.4-0.40.4-0.40.2-0.40.4-0.4-0.20.20.1-0.10.3-0.3
Tibialis anterior weight3.311.414.8-3.73.7-3.7-3.43.8-3.73.73.73.6-3.6-2.73.3-3.33.3-3.63.3-3.33.33.1-3.43.2-3.2-2.62.5
Time to tail flick, vehicle, before self-admin0.60.62.0-1.11.1-1.0-1.40.8-0.60.60.70.7-0.6-0.90.5-0.50.5-0.80.3-0.30.30.9-0.61.1-1.0-0.30.3
Time to tail flick, vehicle, after self-admin1.21.31.7-1.21.2-1.2-1.11.1-1.11.10.81.2-1.2-0.61.1-1.11.1-1.31.2-1.21.21.1-1.21.2-1.2-1.01.0
Time to tail flick, test, before self-admin0.90.81.8-0.50.5-0.5-0.30.9-0.80.90.60.9-0.9-0.71.0-1.01.0-0.91.1-1.11.10.8-1.10.8-0.8-1.31.3
Time to tail flick, test, after self-admin2.22.33.3-1.71.7-1.6-1.61.7-1.61.51.81.5-1.5-1.81.4-1.41.4-1.51.6-1.61.61.8-1.31.2-1.2-0.80.8
Delta time to tail flick, vehicle, before/after SA0.80.81.6-0.70.7-0.8-0.40.9-1.01.00.61.0-1.0-0.41.1-1.11.1-1.01.3-1.31.30.7-0.90.6-0.6-0.80.8
Delta time to tail flick, test, before/after SA0.10.10.4-0.50.5-0.5-0.70.2-0.20.20.40.1-0.1-0.60.0-0.00.0-0.10.1-0.10.10.50.10.2-0.20.4-0.4
Tibia length0.00.00.3-0.10.1-0.1-0.30.10.1-0.10.10.1-0.1-0.10.1-0.10.1-0.10.1-0.10.10.3-0.20.5-0.5-0.30.4
Ambulatory time before self-admin1.21.32.8-1.71.7-1.6-1.41.2-1.71.70.81.3-1.3-1.40.8-0.80.8-1.01.0-1.01.00.9-0.80.2-0.20.1-0.1
Ambulatory time after self-admin1.71.83.8-1.91.9-1.9-1.61.3-1.91.90.91.8-1.8-1.01.0-1.01.0-1.60.9-0.90.90.7-1.41.1-1.1-0.80.7
Bone: tissue strength1.41.43.31.3-1.31.31.8-1.10.8-0.8-1.1-0.90.81.6-1.31.3-1.31.0-1.31.3-1.3-1.40.8-1.31.30.5-0.5
Total heroin consumption1.61.93.01.5-1.51.51.3-1.41.7-1.7-1.7-1.61.61.1-1.21.2-1.21.4-1.31.3-1.3-1.01.5-1.21.21.3-1.2
Bone: trabecular number1.11.85.90.3-0.30.40.2-0.80.7-0.7-1.3-1.11.11.5-1.31.3-1.31.2-1.31.3-1.3-1.61.6-1.61.72.4-2.4
Bone: trabecular spacing1.82.35.6-0.80.9-0.9-0.71.1-1.21.21.21.5-1.5-1.41.5-1.51.5-1.61.5-1.51.51.4-1.91.9-1.9-2.42.4
Bone: trabecular thickness1.01.23.70.2-0.30.30.3-0.70.6-0.6-1.0-0.80.81.4-1.31.3-1.30.9-1.31.3-1.3-1.01.2-1.21.31.9-1.9
Bone: trabecular tissue density0.20.31.30.4-0.40.30.80.1-0.10.20.30.3-0.3-0.00.7-0.70.7-0.40.7-0.70.70.6-0.60.3-0.3-1.11.1
Water consumed over 24 hours0.30.41.1-1.11.0-1.0-1.00.6-0.90.90.40.6-0.6-0.40.2-0.20.2-0.40.2-0.20.20.4-0.1-0.20.30.7-0.7
Number of responses in last shaping day1.21.32.4-1.51.5-1.5-1.51.0-1.41.40.91.3-1.3-1.00.9-0.90.9-1.20.8-0.80.81.0-1.11.1-1.1-0.60.5