Hub : Genes

Ttc39a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Ttc39a 0.06 0.04 3.7e-03 0.03 0.03 0.03 0.03 4.0e-04 3.6e-04 3.4e-04 5.0e-04
2 Adipose mRNA stability Ttc39a 0.06 0.05 3.4e-04 0.04 0.03 0.03 0.03 7.0e-05 1.2e-04 6.3e-04 9.7e-05
3 BLA mRNA stability Ttc39a 0.21 0.22 4.9e-04 -0 0.01 0.04 0.01 4.3e-01 7.3e-02 5.7e-03 6.4e-02
4 NAcc mRNA stability Ttc39a 0.03 0.02 7.1e-06 0.04 0.03 0.04 0.04 1.0e-06 5.3e-06 1.9e-06 1.2e-06
5 Adipose gene expression Ttc39a 0.03 0.02 8.9e-03 -0 0 -0 0.01 4.9e-01 3.7e-01 5.0e-01 1.5e-02
6 Brain mRNA stability Ttc39a 0.09 0.07 3.4e-05 0.04 0.05 0.04 0.04 8.7e-05 2.9e-05 9.7e-05 6.6e-05
7 pVTA intron excision ratio chr5_129422219_129427587 0.05 0.05 8.0e-04 0.03 0.02 0.02 0.02 2.9e-03 9.8e-03 1.2e-02 9.7e-03
8 PL mRNA stability Ttc39a 0.26 0.22 3.2e-07 0.05 0.05 0.06 0.05 2.9e-06 2.2e-06 4.7e-07 1.7e-06
9 NAcc intron excision ratio chr5_129429194_129430661 0.02 0.02 1.9e-03 0.01 0.01 0.01 0.01 1.9e-03 2.0e-03 7.4e-03 5.0e-03
10 IC mRNA stability Ttc39a 0.07 0.05 6.8e-03 0.07 0.03 0.04 0.05 8.2e-04 1.6e-02 6.8e-03 4.1e-03
11 pVTA mRNA stability Ttc39a 0.07 0.09 8.9e-04 0.02 0.02 0.02 0.02 4.5e-03 9.3e-03 7.9e-03 1.0e-02
12 Liver mRNA stability Ttc39a 0.03 0.03 1.7e-03 0.02 0.01 0.01 0.01 3.3e-03 1.6e-02 1.7e-02 1.1e-02
13 pVTA intron excision ratio chr5_129423043_129427587 0.06 0.06 1.2e-03 0.03 0.03 0.02 0.03 1.2e-03 3.8e-03 7.7e-03 3.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.61.02.00.0-0.3-0.4-1.20.7-0.9-1.1-1.0-1.0-1.4-1.4-1.21.2
Area under the delay curve0.20.20.8-0.90.9-0.8-0.1-0.7-0.40.10.1-0.1-0.2-0.20.1-0.1
BMI with tail1.13.86.71.3-0.72.12.5-0.32.61.91.92.32.12.11.9-1.9
BMI without tail0.61.82.80.6-0.21.21.7-0.51.71.41.41.61.51.51.5-1.5
Body weight0.62.55.00.9-0.41.62.0-0.42.21.61.71.82.02.01.1-1.1
Weight adjusted by age0.40.61.41.2-1.01.21.00.61.00.40.40.70.60.60.4-0.3
Bone surface0.30.51.1-0.40.2-0.6-1.00.0-0.6-0.5-0.4-0.6-0.9-0.9-1.01.0
Bone volume0.00.10.3-0.0-0.0-0.1-0.40.1-0.2-0.2-0.1-0.1-0.6-0.6-0.40.4
Breakpoint value in progressive ratio session0.00.00.10.2-0.30.1-0.20.2-0.0-0.2-0.1-0.1-0.2-0.2-0.10.1
Number of licking bursts0.10.20.70.7-0.70.80.40.40.60.10.10.30.20.20.2-0.2
Context. condit. distance diff. score0.50.51.30.4-0.60.00.10.9-0.3-1.0-1.0-0.9-0.4-0.4-1.11.1
Locomotion velocity, session 12.93.15.10.6-1.2-0.2-1.71.8-1.5-2.3-2.2-1.9-1.8-1.8-2.22.2
Locomotion distance, session 10.20.20.70.5-0.60.4-0.00.60.1-0.4-0.4-0.30.00.0-0.80.8
Locomotion velocity, session 22.83.36.20.7-1.3-0.1-1.51.9-1.3-2.2-2.2-1.9-1.9-1.9-2.52.5
Locomotion distance, session 20.50.71.6-0.91.1-0.40.4-1.30.51.21.20.70.60.60.8-0.8
Locomotion velocity, session 30.60.71.5-0.1-0.2-0.5-1.20.6-0.9-1.0-1.0-1.0-1.0-1.0-0.70.7
Locomotion distance, session 30.30.30.8-0.80.9-0.60.2-0.9-0.10.50.50.10.40.40.7-0.7
Stereotopy head waving bouts, day 30.20.20.50.7-0.70.5-0.60.6-0.2-0.3-0.30.1-0.3-0.3-0.10.1
Stereotopy head waving duration, day 31.01.12.61.4-1.61.0-0.81.6-0.2-1.1-1.1-0.3-0.7-0.7-1.11.1
Locomotion velocity, session 70.60.61.8-1.31.2-1.30.6-0.9-0.70.0-0.1-0.7-0.6-0.60.1-0.1
Locomotion distance, session 71.41.85.6-2.42.4-2.10.6-2.0-0.80.80.7-0.5-0.2-0.20.8-0.8
Stereotopy head waving bouts, day 71.61.82.90.5-0.9-0.1-1.51.4-1.4-1.6-1.7-1.3-1.6-1.6-1.41.4
Stereotopy head waving duration, day 71.72.03.10.7-1.10.0-1.61.6-1.3-1.7-1.8-1.3-1.5-1.5-1.61.6
Locomotion velocity, session 81.72.03.5-0.3-0.3-0.8-0.70.9-1.4-1.7-1.8-1.8-1.7-1.7-1.91.9
Locomotion distance, session 80.10.20.6-0.30.2-0.40.5-0.0-0.1-0.2-0.3-0.5-0.1-0.1-0.80.8
Degree of sensitization distance0.30.30.7-0.80.8-0.60.8-0.80.10.50.50.10.10.10.4-0.4
Degree of sensitization stereotypy0.70.81.30.3-0.5-0.2-1.10.9-0.9-1.1-1.1-1.0-1.0-1.0-0.90.9
Conditioned locomotion0.50.51.51.2-1.21.20.91.00.6-0.2-0.40.30.10.1-0.10.1
Cocaine response after cond. corrected1.72.04.1-0.91.3-0.10.6-1.81.21.92.01.31.51.51.6-1.6
Cocaine response after cond. not corrected1.82.14.3-0.40.90.40.9-1.51.52.02.11.61.61.61.7-1.6
Cocaine response before conditioning0.20.20.70.8-0.80.80.50.60.4-0.1-0.20.40.10.1-0.00.0
Saline control response0.91.24.0-2.02.0-1.60.5-1.8-0.40.90.7-0.2-0.2-0.2-0.20.2
Bone: connectivity density1.11.73.5-0.70.3-1.1-1.90.3-1.3-1.1-1.0-1.5-1.7-1.7-1.61.6
Bone: cortical apparent density1.62.24.40.5-0.9-0.3-1.21.5-1.5-1.9-2.0-1.6-2.1-2.1-1.21.2
Bone: cortical area0.91.43.2-0.30.60.41.8-1.11.41.61.51.31.41.40.7-0.7
Bone: cortical porosity1.21.33.91.9-2.01.60.11.80.4-0.9-0.90.1-0.3-0.3-0.70.7
Bone: cortical porosity1.31.43.31.6-1.81.2-0.11.8-0.0-1.2-1.3-0.4-0.7-0.7-1.31.3
Bone: cortical thickness2.03.37.80.50.11.32.8-0.92.12.01.92.22.22.21.8-1.8
Bone: cortical thickness1.82.15.21.1-0.61.52.3-0.11.71.31.21.81.61.61.4-1.4
Bone: cortical tissue density1.92.54.80.6-1.1-0.2-1.31.7-1.5-2.1-2.1-1.6-2.2-2.2-1.31.3
Condit. Reinf. active minus inactive responses0.40.51.30.10.20.40.5-0.50.50.80.80.90.60.61.2-1.1
Condit. Reinf. active-inactive response ratio0.70.81.60.20.20.40.8-0.50.80.90.91.01.11.11.3-1.2
Condit. Reinf. active responses0.81.01.60.10.20.60.9-0.71.01.21.21.31.01.01.3-1.3
Condit. Reinf. inactive responses0.10.20.3-0.50.5-0.20.4-0.60.40.50.50.20.30.30.3-0.4
Incentive salience index mean1.21.52.50.30.10.91.1-0.71.41.51.41.61.41.41.5-1.5
Condit. Reinf. lever presses1.11.62.90.30.20.91.3-0.81.71.61.61.51.61.61.0-1.0
Condit. Reinf. active minus inactive responses0.91.12.3-1.21.5-0.91.3-1.50.11.10.90.60.10.11.3-1.3
Condit. Reinf. active-inactive response ratio0.40.51.2-1.01.1-0.80.7-1.0-0.20.60.50.1-0.2-0.20.7-0.6
Condit. Reinf. active responses0.40.51.4-0.50.8-0.31.2-0.90.30.80.70.70.20.20.9-0.8
Condit. Reinf. inactive responses0.20.30.70.5-0.30.70.6-0.00.80.50.50.80.40.40.3-0.3
Condit. Reinf. lever presses0.71.03.0-1.71.6-1.6-0.9-1.3-0.80.30.4-0.6-0.7-0.70.2-0.2
Condit. Reinf. lever reinforcers received0.40.51.2-0.81.0-0.60.9-1.10.20.80.80.50.10.10.8-0.7
Conditioned reinforcement - actives2.03.45.7-1.42.0-0.51.5-2.41.22.22.21.71.71.72.2-2.2
Conditioned reinforcement - inactives0.00.10.10.1-0.00.20.3-0.10.30.30.30.30.30.30.3-0.3
Conditioned locomotion0.81.11.6-0.61.0-0.10.9-1.20.81.31.21.01.11.11.2-1.2
Patch foraging indifference point 0 sec0.20.30.7-0.10.30.20.7-0.60.70.80.80.70.50.50.3-0.3
Patch foraging indifference point AUC0.20.20.4-0.2-0.0-0.3-0.70.2-0.5-0.5-0.5-0.6-0.5-0.5-0.60.6
Delay disc. indifference point, 0s delay0.60.61.8-1.41.2-1.3-0.6-0.8-0.8-0.3-0.3-0.5-0.6-0.6-0.50.5
Delay disc. indifference point, 16s delay0.80.91.5-0.10.50.30.9-0.90.91.21.21.11.01.01.2-1.2
Delay disc. indifference point, 2s delay0.10.10.2-0.40.4-0.50.0-0.2-0.4-0.2-0.2-0.3-0.3-0.3-0.20.2
Delay disc. indifference point, 24s delay0.10.10.4-0.50.4-0.60.1-0.2-0.6-0.3-0.4-0.3-0.5-0.5-0.10.1
Delay disc. indifference point, 4s delay0.10.10.3-0.30.4-0.30.2-0.4-0.10.20.20.1-0.0-0.00.5-0.5
Delay disc. indifference point, 8s delay0.10.10.5-0.70.7-0.6-0.0-0.6-0.20.20.2-0.0-0.1-0.10.1-0.1
Indifference point function ln k0.20.40.70.10.10.40.8-0.40.90.80.80.80.60.60.4-0.4
Indifference point function log k0.20.40.70.10.10.40.8-0.40.90.80.80.80.60.60.4-0.4
Patch foraging total patch changes 0 sec0.10.20.50.10.10.30.6-0.40.70.70.70.60.40.40.2-0.2
Patch foraging total patch changes 12 sec0.81.01.5-0.3-0.1-0.7-1.10.5-1.1-1.2-1.1-1.1-1.2-1.2-1.21.2
Patch foraging total patch changes 18 sec0.10.20.30.00.10.20.4-0.30.50.50.50.50.50.50.6-0.6
Patch foraging total patch changes 24 sec0.50.81.40.5-0.20.91.2-0.31.21.01.01.11.01.00.8-0.8
Patch foraging total patch changes 6 sec0.20.30.9-0.80.9-0.60.1-0.90.00.50.60.20.10.10.2-0.2
Patch foraging time to switch 0 sec0.71.42.60.3-0.7-0.3-1.41.2-1.3-1.6-1.6-1.5-1.3-1.3-1.11.1
Patch foraging water rate 0 sec0.92.03.60.7-0.11.21.9-0.61.91.71.71.81.51.51.2-1.2
Patch foraging water rate 12 sec1.22.64.10.00.50.81.9-1.21.92.02.01.82.02.01.5-1.5
Patch foraging water rate 18 sec0.10.20.50.7-0.70.50.40.60.2-0.2-0.20.3-0.3-0.3-0.30.4
Patch foraging water rate 24 sec0.10.20.50.7-0.70.60.30.50.4-0.1-0.10.2-0.1-0.1-0.40.4
Patch foraging water rate 6 sec0.81.22.50.5-0.10.91.6-0.51.41.21.21.51.01.01.0-0.9
Seeking ratio, delayed vs. immediate footshock1.82.23.6-0.20.70.61.8-1.31.71.91.81.61.81.81.3-1.5
Distance traveled before self-admin0.20.30.70.8-0.70.80.10.40.60.30.40.40.40.40.4-0.4
Distance traveled after self-admin0.70.91.50.7-0.41.00.9-0.21.21.01.11.10.90.91.0-1.0
Extensor digitorum longus weight1.04.07.11.7-0.92.22.6-0.02.21.61.72.71.91.92.4-2.4
Bone: elastic displacement0.40.51.71.3-1.31.2-0.01.00.5-0.3-0.30.30.40.40.2-0.2
Bone: elastic work0.10.10.30.4-0.30.50.40.10.50.20.20.40.50.50.2-0.2
Bone: endosteal estimation0.20.51.8-0.30.2-0.4-1.3-0.1-0.2-0.2-0.0-0.3-0.3-0.3-1.41.4
Bone: endosteal perimeter0.40.92.8-1.31.1-1.3-1.7-0.7-0.8-0.10.1-0.7-0.7-0.7-0.80.8
Epididymis fat weight0.10.41.1-1.00.9-1.0-0.4-0.6-0.6-0.2-0.1-0.5-0.3-0.3-0.50.5
Delta time in closed arm before/after self-admin0.00.00.1-0.30.3-0.20.1-0.2-0.10.10.1-0.0-0.1-0.10.1-0.1
Delta time in open arm before/after self-admin0.10.10.3-0.20.3-0.0-0.3-0.40.30.40.50.40.20.20.3-0.3
Diff in mean of infusions in LGA sessions0.30.41.4-1.11.2-0.90.4-1.0-0.20.40.40.10.00.00.4-0.4
Delay discount exponential model param0.20.20.80.9-0.90.80.00.70.4-0.1-0.10.10.20.2-0.20.2
Extinction: sum of active levers before priming0.70.82.71.7-1.61.50.11.20.7-0.1-0.10.30.30.3-0.10.1
Active lever presses in extinction session 61.81.82.8-0.81.2-0.11.1-1.61.01.71.71.41.31.31.7-1.7
Bone: final force0.10.20.4-0.60.6-0.5-0.3-0.5-0.20.10.2-0.10.10.1-0.50.5
Bone: final moment0.10.20.5-0.60.7-0.5-0.1-0.6-0.00.30.40.10.30.3-0.40.4
Food consumed during 24 hour testing period1.41.95.5-2.12.4-1.60.5-2.30.01.51.60.60.50.50.9-0.9
Glucose0.20.40.9-0.70.9-0.50.3-0.90.20.70.80.40.40.40.7-0.7
Heart weight1.42.14.11.8-1.32.01.90.61.81.01.01.71.41.41.1-1.1
Delay discount hyperbolic model param0.20.20.60.8-0.80.70.00.60.4-0.0-0.00.20.30.3-0.10.1
Intermittent access intake day 1-15 change0.40.71.2-0.60.9-0.20.6-1.10.61.11.10.70.80.81.0-1.0
Intermittent access intake escalation0.30.61.0-0.20.50.20.8-0.80.81.01.00.80.80.80.9-0.9
Intermittent access intake escalation 20.10.10.2-0.20.30.00.3-0.40.30.50.50.30.30.30.4-0.4
Intermitt. access day 1 inactive lever presses0.51.72.5-0.10.60.41.5-1.11.21.51.61.51.51.51.6-1.6
Intermitt. access day 15 inactive lever presses0.40.81.60.8-0.61.01.30.11.10.80.81.00.80.80.9-0.9
Intermitt. access escalation Index0.20.30.90.9-0.90.70.20.80.1-0.4-0.40.00.00.0-0.30.3
Intermittent access day 1 total infusions0.10.20.80.8-0.90.60.10.80.1-0.4-0.4-0.1-0.2-0.2-0.40.4
Intermittent access day 15 total infusions0.20.30.60.6-0.50.80.70.10.70.50.50.60.60.60.4-0.4
Intermittent access terminal intake (last 3 days)0.00.10.20.4-0.40.40.30.20.30.10.10.20.20.20.1-0.1
Intermittent access total infusions0.10.20.60.7-0.70.60.10.60.3-0.1-0.20.0-0.1-0.1-0.20.2
Intermittent access day 1 locomotion0.10.10.30.6-0.60.50.10.50.1-0.2-0.20.0-0.0-0.0-0.20.2
Intermittent access day 15 total locomotion0.20.30.8-0.70.8-0.40.3-0.90.20.70.70.40.50.50.6-0.6
Intermittent access total locomotion0.10.10.50.7-0.70.60.30.50.30.0-0.00.20.10.1-0.10.1
Intermittent access standard deviation1.12.33.50.00.50.71.8-1.11.61.91.81.71.81.81.8-1.8
Left kidney weight4.219.329.00.70.82.75.4-2.74.95.25.15.25.35.34.9-4.9
Right kidney weight2.410.916.91.00.12.44.1-1.74.03.83.74.04.14.13.3-3.3
Cocaine induced anxiety0.91.33.31.8-1.61.81.50.91.30.60.50.90.80.80.6-0.6
Post-drug Anxiety2.22.35.92.4-2.22.42.01.31.60.80.71.11.01.00.8-0.8
Baseline Anxiety0.10.10.20.10.00.20.5-0.20.40.40.40.50.40.40.4-0.4
Tail length0.00.10.50.1-0.10.1-0.20.20.1-0.2-0.1-0.20.10.1-0.70.7
Length with tail0.10.51.0-0.20.40.20.7-0.70.90.90.90.71.01.00.1-0.1
Length without tail1.03.25.6-0.61.10.42.1-1.82.02.42.42.02.12.11.5-1.5
Times rat made contact with spout1.11.33.6-1.61.8-1.2-0.3-1.90.11.31.40.50.40.40.8-0.8
Lifetime Intake0.00.00.00.1-0.10.1-0.00.10.0-0.1-0.1-0.0-0.1-0.1-0.10.1
Liver weight, left0.20.30.9-0.90.8-0.9-0.4-0.6-0.6-0.00.0-0.2-0.1-0.10.3-0.3
Liver weight, right0.20.31.0-1.00.8-1.0-0.5-0.5-0.7-0.1-0.1-0.6-0.2-0.20.2-0.2
Locomotor activity0.71.03.4-1.81.9-1.4-0.3-1.7-0.40.90.8-0.1-0.1-0.10.5-0.5
Locomotor testing distance0.81.44.1-1.92.0-1.20.0-2.00.01.31.20.10.40.40.7-0.7
Locomotor testing rearing0.91.96.3-2.42.5-1.8-0.1-2.3-0.31.21.20.00.10.10.7-0.7
Locomotion in novel chamber2.73.55.7-1.11.7-0.11.2-2.21.62.32.41.92.02.02.2-2.2
Locomotion in novel chamber post-restriction0.50.92.91.7-1.61.60.11.10.90.10.10.40.70.70.00.2
Fecal boli incidents, locomotor time 10.30.41.5-1.11.2-0.90.5-1.1-0.20.40.40.10.10.10.2-0.2
Change in fecal boli incidents, locomotor task0.40.40.6-0.50.2-0.6-0.60.0-0.6-0.5-0.6-0.7-0.7-0.7-0.80.8
Time >=10cm from walls, locomotor time 11.61.73.11.1-1.60.6-1.41.8-0.5-1.4-1.3-1.1-1.3-1.3-1.51.5
Bouts of movement, locomotor time 10.70.83.0-0.80.5-1.0-1.7-0.0-1.1-0.9-0.7-0.9-0.7-0.7-0.70.7
Total resting periods, locomotor time 10.50.52.4-0.40.2-0.7-1.50.2-0.9-0.8-0.6-0.7-0.6-0.6-0.60.6
Rest time, locomotor task time 10.20.20.8-0.90.8-0.8-0.3-0.5-0.5-0.1-0.1-0.3-0.1-0.1-0.10.1
Distance moved, locomotor task time 10.50.72.31.4-1.51.00.01.30.1-0.6-0.7-0.1-0.4-0.4-0.70.7
Vertical activity count, locomotor time 10.10.30.90.4-0.20.60.9-0.10.70.60.40.60.50.50.4-0.4
Time >=10cm from walls, locomotor time 20.20.20.80.8-0.90.70.30.70.4-0.2-0.20.10.10.1-0.30.3
Bouts of movement, locomotor time 20.40.71.71.0-1.20.4-1.01.3-0.5-1.1-0.8-0.5-0.5-0.5-0.30.3
Total resting periods, locomotor time 20.30.61.40.9-1.00.3-1.21.2-0.6-1.0-0.7-0.5-0.5-0.5-0.30.3
Rest time, locomotor task time 20.20.30.8-0.80.8-0.9-0.5-0.4-0.7-0.3-0.1-0.3-0.5-0.5-0.00.0
Distance moved, locomotor task time 20.80.91.71.0-0.81.31.20.31.20.70.50.91.31.30.5-0.5
Vertical activity count, locomotor time 21.21.73.1-0.00.40.61.7-1.01.41.61.31.31.81.81.3-1.3
Light reinforcement 10.20.41.01.0-0.91.00.60.60.80.10.10.50.60.6-0.30.3
Light reinforcement 20.91.42.90.9-0.51.31.7-0.11.61.11.11.41.51.50.6-0.6
Bone: marrow area0.20.41.8-0.30.2-0.3-1.3-0.1-0.1-0.10.1-0.2-0.2-0.2-1.31.3
Bone: maximum diameter0.10.20.50.3-0.20.50.20.00.70.40.40.40.50.5-0.40.4
Bone: maximum force0.10.20.4-0.50.5-0.4-0.2-0.5-0.00.30.30.00.10.1-0.60.6
Bone: maximum moment0.10.20.4-0.50.6-0.4-0.0-0.60.10.40.40.20.30.3-0.50.5
Mean time between licks in bursts0.81.83.2-1.41.0-1.8-0.9-0.3-1.8-1.0-1.1-1.7-1.8-1.8-1.11.1
Mean num. licks in bursts0.60.92.2-1.21.5-0.90.0-1.50.21.01.20.60.70.70.7-0.7
Cd content in liver0.30.41.0-0.40.2-0.7-0.40.2-1.0-0.7-0.8-0.8-0.8-0.8-0.30.3
Co content in liver0.10.10.3-0.50.5-0.5-0.1-0.4-0.30.10.10.00.30.30.3-0.3
Cu content in liver1.21.54.4-2.12.0-2.0-0.9-1.6-1.10.30.3-0.6-0.9-0.90.1-0.1
Fe content in liver0.60.71.51.1-0.81.20.10.41.10.40.60.91.21.20.5-0.5
K content in liver1.61.54.7-2.22.1-2.1-0.9-1.7-1.00.40.3-0.6-0.6-0.6-0.20.2
Mg content in liver2.22.25.9-2.12.3-1.40.6-2.40.11.71.60.50.80.81.4-1.4
Mn content in liver0.20.20.40.0-0.2-0.2-0.40.4-0.6-0.6-0.6-0.5-0.6-0.60.1-0.1
Na content in liver0.50.61.0-0.80.6-1.0-1.0-0.3-0.8-0.4-0.4-0.7-0.7-0.7-1.01.0
Rb content in liver0.20.30.9-0.91.0-0.9-0.2-0.8-0.30.30.40.1-0.1-0.10.3-0.3
Se content in liver0.30.41.2-1.11.0-1.0-0.0-0.8-0.60.10.1-0.5-0.5-0.5-0.10.1
Sr content in liver0.00.00.00.2-0.20.1-0.10.20.1-0.1-0.1-0.0-0.0-0.0-0.20.2
Zn content in liver1.21.43.8-1.91.6-1.9-0.7-1.1-1.3-0.1-0.3-1.1-1.1-1.1-0.20.2
Bone: minimum diameter0.61.23.4-1.51.7-0.90.2-1.90.51.41.50.60.60.60.1-0.1
Time in familiar zone, hab. session 10.50.50.90.3-0.6-0.0-0.30.8-0.6-0.9-0.9-0.7-0.8-0.8-0.80.8
Time in novel zone, hab. session 10.20.20.6-0.80.8-0.7-0.7-0.7-0.30.30.3-0.2-0.2-0.20.3-0.3
Total zone transitions, hab. session 10.50.62.20.8-1.00.7-0.40.90.1-0.5-0.6-0.3-0.3-0.3-1.51.5
Total locomotion distance, hab. session 10.50.72.01.4-1.31.40.31.00.8-0.1-0.10.50.50.5-0.50.5
Locomotion velocity, hab. session 10.30.51.31.1-1.11.10.20.80.6-0.1-0.10.30.50.5-0.50.5
Time in familiar zone, hab. session 20.80.92.6-1.51.4-1.6-0.4-1.0-1.2-0.0-0.1-0.7-0.7-0.70.4-0.4
Time in novel zone, hab. session 20.40.41.11.1-1.01.0-0.20.80.6-0.2-0.10.30.30.3-0.40.4
Total zone transitions, hab. session 20.20.20.7-0.80.8-0.7-0.1-0.7-0.20.30.3-0.3-0.0-0.0-0.50.5
Total locomotion distance, hab. session 20.20.20.4-0.00.20.20.5-0.40.40.60.60.50.60.60.4-0.4
Locomotion velocity, hab. session 20.20.30.50.00.20.30.6-0.40.50.70.60.60.70.70.4-0.4
Novel to familiar place preference ratio1.41.63.2-0.91.3-0.30.5-1.60.91.71.81.11.21.21.4-1.4
Novelty place preference0.80.91.8-0.70.9-0.20.2-1.20.71.21.40.90.90.91.1-1.1
Time in novel zone, NPP test0.60.71.4-0.70.9-0.20.0-1.10.51.11.20.70.70.71.0-1.0
Total zone transitions, NPP test0.40.61.30.8-0.51.11.00.01.10.80.71.01.01.00.1-0.1
Total locomotion distance, NPP test0.70.91.50.7-0.41.00.9-0.11.00.90.81.21.21.21.0-1.0
Locomotion velocity, NPP test1.01.52.50.8-0.31.21.4-0.31.41.21.11.61.51.51.3-1.3
Intraocular pressure0.30.40.7-0.40.6-0.10.5-0.80.30.70.70.70.50.50.8-0.8
Delta distance traveled before/after self-admin1.01.01.6-0.10.50.31.2-0.91.01.31.21.31.11.11.1-1.1
Delta ambulatory time before/after self-admin0.60.81.2-0.20.50.20.9-0.90.81.11.11.00.90.91.1-1.1
Parametrial fat weight0.10.20.90.3-0.40.3-0.30.40.0-0.2-0.3-0.3-0.2-0.2-0.90.9
Pavlov. Cond. lever latency1.11.42.4-0.90.5-1.4-1.10.2-1.5-1.2-1.2-1.6-1.5-1.5-1.11.1
Pavlov. Cond. magazine entry latency0.20.31.1-0.30.1-0.5-1.00.1-0.6-0.4-0.4-0.6-0.5-0.5-0.40.4
Pavlov. Cond. change in total contacts0.00.00.00.1-0.00.10.0-0.00.20.10.10.1-0.0-0.00.0-0.0
Pavlov. Cond. index score0.20.20.50.3-0.10.50.2-0.20.60.60.60.60.70.70.4-0.4
Pavlov. Cond. latency score0.20.30.50.3-0.00.50.2-0.30.60.70.70.70.70.70.5-0.5
Pavlov. Cond. lever contacts0.91.01.70.9-0.51.20.9-0.11.31.01.01.31.31.30.9-0.9
Pavlov. Cond. magazine entry number0.20.21.30.10.10.31.1-0.30.60.50.40.50.40.40.3-0.3
Pavlov. Cond. intertrial magazine entries0.91.02.1-1.01.3-0.50.9-1.50.41.31.20.70.70.71.2-1.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.3-0.00.50.3-0.30.70.70.80.70.90.90.6-0.6
Pavlov. Cond. response bias0.10.10.30.5-0.40.5-0.20.20.40.10.20.30.40.40.1-0.1
Pavlov. Cond. lever latency1.31.85.62.3-2.42.00.62.10.6-1.0-1.00.30.30.3-0.70.7
Pavlov. Cond. magazine entry latency2.32.88.0-2.82.6-2.8-1.7-1.9-1.70.10.3-1.2-1.1-1.10.4-0.4
Pavlov. Cond. change in total contacts1.32.06.8-2.62.6-2.3-0.4-2.2-0.80.90.9-0.5-0.5-0.50.2-0.2
Pavlov. Cond. index score2.33.19.7-3.13.0-2.9-1.4-2.4-1.40.60.8-0.9-0.8-0.80.6-0.6
Pavlov. Cond. latency score2.23.09.0-3.02.9-2.8-1.4-2.4-1.30.70.8-0.9-0.8-0.80.6-0.6
Pavlov. Cond. lever contacts1.01.44.4-2.12.1-1.8-0.7-1.9-0.60.80.9-0.3-0.4-0.40.5-0.5
Pavlov. Cond. magazine entry number2.93.59.52.9-2.53.12.11.72.20.40.31.81.71.70.4-0.4
Pavlov. Cond. intertrial magazine entries0.60.92.81.7-1.71.30.71.50.3-0.7-0.80.3-0.3-0.3-0.10.1
Pavlov. Cond. lever-magazine prob. diff.2.63.510.8-3.33.2-3.1-1.5-2.6-1.50.70.8-1.0-0.8-0.80.6-0.6
Pavlov. Cond. response bias1.62.16.6-2.62.4-2.4-1.1-1.9-1.20.40.5-0.8-0.9-0.90.1-0.1
Time in closed arm before self-admin0.30.40.80.5-0.70.1-0.10.9-0.5-0.8-0.9-0.7-0.6-0.6-0.80.8
Time in closed arm after self-admin0.30.30.60.6-0.70.30.30.8-0.2-0.6-0.7-0.5-0.5-0.5-0.50.5
Time in open arm before self-admin0.40.51.6-1.21.3-1.0-0.3-1.1-0.30.40.50.0-0.0-0.00.4-0.4
Time in open arm after self-admin0.80.81.7-0.60.9-0.1-0.2-1.10.71.11.30.90.80.81.1-1.1
Bone: periosteal estimation0.20.40.9-0.00.20.30.3-0.50.90.90.90.80.80.8-0.40.4
Bone: periosteal perimeter0.10.20.5-0.60.6-0.3-0.2-0.70.20.50.60.20.20.2-0.30.3
Bone: post-yield work0.20.31.2-0.30.3-0.3-0.9-0.2-0.1-0.00.1-0.2-0.1-0.1-1.11.1
Progressive ratio test 1 active lever presses0.50.61.10.6-0.40.91.0-0.11.00.80.80.90.90.90.7-0.7
Progressive ratio test 1 breakpoint0.50.71.10.7-0.51.01.0-0.01.10.80.80.90.90.90.7-0.7
Progressive ratio test 1 inactive lever presses0.30.40.80.7-0.50.80.90.10.90.60.60.70.60.60.6-0.6
Progressive ratio test 2 active lever presses0.40.40.80.6-0.40.80.8-0.00.90.70.60.70.60.60.6-0.6
Progressive ratio test 2 breakpoint0.40.51.10.8-0.71.00.90.21.00.60.60.70.60.60.5-0.5
Progressive ratio test 2 inactive lever presses0.00.00.10.00.10.10.3-0.20.20.30.30.30.10.10.3-0.3
Incentive Sensitization - Responses0.00.00.00.1-0.10.10.00.00.10.00.00.0-0.1-0.1-0.00.0
Incentive Sensitization - Breakpoint0.00.00.00.1-0.10.10.10.00.20.10.10.1-0.0-0.00.0-0.0
Sum of active levers in priming session hrs 5-60.40.41.31.2-1.11.1-0.10.70.70.10.20.50.30.30.1-0.1
Progressive ratio0.20.30.7-0.20.40.10.4-0.60.50.70.70.50.80.80.4-0.7
Food seeking constrained by brief footshock1.92.34.2-0.1-0.5-0.8-1.51.2-1.7-2.0-2.1-1.9-1.6-1.6-1.91.6
Seeking ratio, punishment vs. effort2.13.04.80.0-0.7-0.8-1.91.4-1.9-2.2-2.2-2.0-2.1-2.1-1.91.9
Retroperitoneal fat weight0.10.30.90.1-0.3-0.1-0.50.4-0.4-0.5-0.6-0.6-0.5-0.5-0.90.9
Reaction time number correct0.30.61.81.3-1.31.00.31.20.4-0.5-0.50.3-0.3-0.3-0.50.5
Reaction time mean minus median0.92.16.7-2.52.6-2.4-0.6-2.1-1.20.50.6-0.2-0.3-0.31.0-1.0
Reaction time mean minus median AUC0.61.54.3-2.12.1-2.0-0.5-1.6-1.10.30.4-0.3-0.5-0.51.0-1.0
Reaction time num false alarms1.21.73.5-1.31.7-0.70.8-1.90.71.61.61.01.31.31.4-1.4
Reaction time num false alarms AUC1.82.85.0-1.41.9-0.61.3-2.21.02.12.11.41.71.71.8-1.8
Reaction time trials correct on left0.30.61.81.3-1.31.00.31.20.4-0.5-0.50.3-0.3-0.3-0.50.5
Reaction time trials on left0.20.41.41.2-1.10.90.31.00.3-0.5-0.40.3-0.3-0.3-0.50.5
Reaction time mean0.91.44.5-2.12.0-2.0-0.9-1.5-1.10.20.2-0.7-0.7-0.70.4-0.4
Reaction time mean AUC0.81.23.4-1.81.7-1.8-1.0-1.2-1.2-0.1-0.1-0.8-0.9-0.90.2-0.2
Median of all reaction times0.60.92.4-1.61.4-1.5-0.9-0.9-1.0-0.1-0.1-0.8-0.8-0.80.0-0.0
Reaction time omissions1.52.26.2-2.32.5-1.90.1-2.3-0.61.11.10.10.10.11.6-1.6
Reaction time false alarm rate2.53.46.8-1.82.3-0.91.1-2.60.92.22.21.21.81.82.1-2.1
Reaction time premature initiation rate0.30.41.1-1.01.0-1.0-0.3-0.8-0.60.10.1-0.3-0.5-0.5-0.20.2
Reaction time premature initiations0.10.20.4-0.30.2-0.4-0.3-0.1-0.5-0.3-0.3-0.3-0.7-0.7-0.50.6
Std. dev. reaction times1.32.47.4-2.72.7-2.4-0.5-2.3-1.00.70.8-0.2-0.2-0.21.2-1.2
Reaction time trials completed0.20.41.41.2-1.10.90.31.00.3-0.5-0.40.3-0.3-0.3-0.50.5
Reaction time trials AUC0.20.41.31.1-1.10.90.40.90.5-0.3-0.20.4-0.1-0.1-0.30.3
Run reversals in cocaine runway, females0.30.31.0-1.00.9-0.9-0.8-0.6-0.6-0.1-0.1-0.4-0.3-0.3-0.2-0.1
Run reversals in cocaine runway, males2.32.33.8-1.11.6-0.40.5-1.90.91.71.91.51.51.52.0-2.0
Latency to leave start box in cocaine runway0.91.02.11.3-1.01.40.60.41.20.80.91.20.90.91.0-0.7
Latency to leave start box in cocaine runway, F1.51.73.71.7-1.31.91.00.61.71.01.11.61.21.21.1-0.7
Latency to leave start box in cocaine runway, M0.30.31.1-1.11.0-0.9-0.2-0.7-0.6-0.1-0.1-0.2-0.2-0.20.2-0.2
Std. dev. time between licks in bursts1.82.44.2-1.00.4-1.5-1.30.3-1.9-1.5-1.5-1.9-2.0-2.0-1.61.6
Total sessions with >9 infusions0.10.10.4-0.60.6-0.5-0.3-0.5-0.20.10.1-0.1-0.1-0.10.0-0.0
Short access day 1 total inactive lever presses1.21.63.10.7-0.31.11.8-0.41.51.41.41.61.41.41.4-1.4
Short access day 10 total inactive lever presses0.10.20.4-0.00.20.20.6-0.30.40.50.50.50.40.40.6-0.6
Short access day 1 total infusions0.00.00.00.2-0.20.20.10.10.20.00.00.10.10.10.0-0.0
Short access day 10 total infusions0.40.51.61.3-1.21.20.60.90.70.10.00.30.40.40.0-0.0
Short access total infusions0.00.00.1-0.10.0-0.2-0.30.1-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2
Short access day 1 locomotion1.01.21.7-0.71.0-0.10.9-1.30.81.31.31.11.21.21.3-1.3
Short access day 10 total locomotion0.30.61.10.3-0.10.60.9-0.30.90.80.80.81.01.00.8-0.8
Short access total locomotion0.00.00.10.1-0.20.0-0.20.2-0.1-0.2-0.2-0.2-0.1-0.1-0.20.2
One hour access (0.3 mA shock)0.10.10.3-0.40.3-0.4-0.5-0.1-0.4-0.2-0.2-0.4-0.5-0.5-0.30.3
Compulsive drug intake0.60.81.20.5-0.80.1-0.81.1-0.7-1.1-1.0-0.8-0.9-0.9-1.11.1
One hour access (shock baseline)0.61.01.7-0.20.60.31.0-1.01.01.31.21.01.11.11.2-1.2
Social response proportion0.20.30.5-0.70.6-0.7-0.6-0.4-0.6-0.1-0.2-0.5-0.6-0.60.2-0.2
Social responses1.01.32.5-0.90.6-1.2-1.5-0.0-1.5-0.9-1.0-1.3-1.6-1.6-0.80.8
Social time0.10.20.6-0.50.5-0.30.1-0.6-0.00.40.30.10.20.20.8-0.8
Soleus weight2.26.511.10.80.21.83.3-1.42.82.82.83.22.62.63.1-3.1
Bone: stiffness0.10.10.3-0.50.4-0.40.1-0.4-0.10.10.1-0.1-0.2-0.2-0.50.5
Tibialis anterior weight3.110.418.23.1-2.04.04.30.44.02.52.54.23.53.53.0-3.0
Time to tail flick, vehicle, before self-admin1.71.82.81.3-0.91.71.20.21.71.21.31.51.61.61.2-1.2
Time to tail flick, vehicle, after self-admin0.60.82.01.3-1.11.40.70.61.10.50.50.80.80.80.5-0.5
Time to tail flick, test, before self-admin3.73.910.13.1-2.73.21.51.52.41.01.01.81.71.71.0-1.0
Time to tail flick, test, after self-admin1.31.33.21.3-1.11.51.80.41.40.80.71.01.01.01.0-1.0
Delta time to tail flick, vehicle, before/after SA0.00.00.10.4-0.30.3-0.10.20.20.00.10.10.00.00.1-0.1
Delta time to tail flick, test, before/after SA0.70.72.5-1.61.5-1.4-0.1-1.1-0.80.0-0.0-0.5-0.4-0.40.1-0.1
Tibia length0.10.30.6-0.00.10.30.4-0.30.80.60.50.30.60.6-0.70.7
Ambulatory time before self-admin0.10.10.20.4-0.40.5-0.00.20.40.20.20.20.20.20.2-0.2
Ambulatory time after self-admin0.40.51.00.6-0.40.80.5-0.11.00.80.80.90.70.70.8-0.8
Bone: tissue strength0.80.81.7-1.10.9-1.3-1.2-0.4-1.1-0.5-0.4-1.0-0.8-0.8-0.80.8
Total heroin consumption0.20.30.6-0.20.0-0.4-0.80.2-0.5-0.5-0.5-0.6-0.8-0.8-0.50.5
Bone: trabecular number0.81.32.9-0.40.0-0.7-1.10.4-1.0-1.0-1.1-1.3-1.7-1.7-1.41.4
Bone: trabecular spacing1.11.52.90.8-0.51.21.6-0.11.41.01.01.31.71.71.1-1.1
Bone: trabecular thickness0.50.71.3-0.90.6-1.1-1.2-0.3-1.1-0.5-0.5-0.8-1.1-1.1-0.20.2
Bone: trabecular tissue density0.30.51.31.0-1.10.6-0.21.1-0.3-0.8-0.9-0.2-0.5-0.50.0-0.0
Water consumed over 24 hours1.11.53.6-1.41.7-0.80.8-1.90.61.61.60.80.80.81.1-1.1
Number of responses in last shaping day2.02.23.3-0.10.60.51.8-1.21.51.81.81.81.61.61.8-1.8