Hub : Genes

Ttc38

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr7_116931677_116934346 0.03 0.03 6.3e-03 0.02 0.01 0.01 -0 5.3e-03 1.4e-02 6.7e-02 6.5e-01
2 PL gene expression Ttc38 0.07 0.04 3.8e-10 0.06 0.09 0.08 0.08 1.1e-06 4.0e-10 4.0e-09 3.8e-09
3 pVTA gene expression Ttc38 0.1 0.06 1.2e-04 0.03 0.08 0.07 0.05 1.8e-02 3.0e-04 4.7e-04 4.0e-03
4 Liver gene expression Ttc38 0.07 0.05 6.0e-06 0.05 0.04 0.05 0.05 1.3e-06 1.6e-05 3.2e-06 2.0e-06
5 NAcc gene expression Ttc38 0.06 0.03 7.6e-10 0.09 0.08 0.09 0.08 1.5e-10 9.8e-10 4.0e-10 7.7e-10
6 BLA gene expression Ttc38 0.1 0.07 1.8e-03 0.04 0.04 0.03 0.03 1.9e-03 3.1e-03 8.9e-03 8.1e-03
7 IL gene expression Ttc38 0.17 0.11 4.0e-03 0.09 0.09 0.04 0.06 3.1e-03 4.5e-03 3.5e-02 1.8e-02
8 Brain isoform ratio XR_355878.3 0.11 0.08 7.6e-03 0.01 0.01 0.03 0 2.1e-02 2.3e-02 1.7e-03 2.3e-01
9 Brain gene expression Ttc38 0.11 0.06 1.1e-07 0.07 0.08 0.07 0.06 1.8e-07 8.9e-08 4.2e-07 1.6e-06
10 Liver isoform ratio NM_001130499.1 0.04 0.03 2.2e-03 0 0.01 0.01 0.01 1.5e-01 1.2e-02 1.6e-02 4.1e-02
11 Adipose gene expression Ttc38 0.04 0.02 2.0e-04 0.01 0.02 0.02 0.02 1.0e-02 2.2e-03 1.7e-03 6.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.11.9-0.91.21.3-0.8-1.4-0.9-1.20.81.3-0.6-0.6
Area under the delay curve3.73.96.3-2.52.42.3-2.0-2.3-1.9-2.21.41.8-0.8-1.7
BMI with tail2.27.112.73.2-2.7-2.91.63.51.63.3-3.6-1.7-0.32.8
BMI without tail1.83.86.31.6-2.0-2.02.52.02.22.0-1.8-2.21.51.3
Body weight2.18.811.93.2-3.3-3.23.03.23.03.2-3.4-2.81.91.6
Weight adjusted by age1.92.14.61.9-1.5-1.61.12.01.42.1-1.2-1.20.00.7
Bone surface0.20.30.8-0.50.70.8-0.1-0.7-0.3-0.70.20.6-0.3-0.9
Bone volume0.30.51.1-0.80.90.9-0.3-1.0-0.4-0.90.60.7-0.1-0.7
Breakpoint value in progressive ratio session0.50.62.0-0.10.50.3-1.0-0.1-1.3-0.50.40.7-1.4-0.4
Number of licking bursts0.30.31.3-0.50.40.60.4-0.50.3-0.70.10.01.1-0.8
Context. condit. distance diff. score1.11.32.50.9-1.5-1.60.70.81.11.31.1-1.60.30.9
Locomotion velocity, session 11.92.04.41.3-1.3-1.11.90.82.11.1-1.9-1.41.50.5
Locomotion distance, session 10.20.30.8-0.50.20.30.4-0.70.6-0.20.0-0.30.9-0.9
Locomotion velocity, session 23.84.47.61.8-2.1-1.92.41.52.41.9-2.8-2.02.02.1
Locomotion distance, session 20.20.30.5-0.50.60.5-0.5-0.6-0.5-0.2-0.30.6-0.70.6
Locomotion velocity, session 33.33.99.11.1-2.1-1.92.60.92.71.1-0.7-2.83.00.5
Locomotion distance, session 30.60.63.6-0.1-0.4-0.20.9-0.20.9-0.2-0.1-1.01.9-0.6
Stereotopy head waving bouts, day 30.91.12.40.9-1.2-1.31.10.81.41.00.3-1.60.50.6
Stereotopy head waving duration, day 32.22.65.01.4-1.7-1.91.81.32.02.00.1-2.20.51.2
Locomotion velocity, session 71.82.04.70.6-1.5-1.51.81.11.61.3-0.2-2.21.80.3
Locomotion distance, session 70.30.31.20.0-0.5-0.40.50.60.60.2-0.3-0.61.10.8
Stereotopy head waving bouts, day 71.41.53.71.0-1.5-1.61.40.81.51.20.2-1.90.90.4
Stereotopy head waving duration, day 70.60.71.90.5-0.9-1.01.00.41.10.90.4-1.40.70.1
Locomotion velocity, session 84.15.07.32.6-2.6-2.71.82.12.12.7-1.7-2.10.52.6
Locomotion distance, session 80.50.71.30.7-1.1-1.10.50.51.00.90.1-1.10.71.0
Degree of sensitization distance0.70.72.51.0-0.8-0.8-0.11.2-0.10.9-0.80.0-0.91.6
Degree of sensitization stereotypy0.60.71.40.8-1.0-1.01.00.50.90.80.0-1.20.60.2
Conditioned locomotion0.10.10.20.0-0.2-0.30.20.30.40.40.1-0.40.20.2
Cocaine response after cond. corrected0.40.52.90.5-0.3-0.10.60.20.90.4-1.70.10.9-0.2
Cocaine response after cond. not corrected0.50.51.90.1-0.20.10.8-0.11.10.1-1.2-0.21.4-0.4
Cocaine response before conditioning0.20.30.8-0.80.40.40.1-0.7-0.1-0.70.9-0.10.6-0.5
Saline control response0.10.20.50.7-0.3-0.1-0.10.60.10.1-0.70.3-0.0-0.6
Bone: connectivity density0.30.41.0-0.60.70.9-0.1-0.9-0.4-1.00.40.70.0-0.7
Bone: cortical apparent density1.11.42.2-1.21.31.2-1.5-1.1-1.3-1.21.31.1-0.8-0.9
Bone: cortical area0.91.43.41.8-1.3-1.40.61.50.61.5-1.4-0.6-0.40.6
Bone: cortical porosity0.91.03.01.7-1.0-0.90.01.10.30.9-1.70.1-0.50.7
Bone: cortical porosity0.80.92.91.7-1.0-0.90.01.10.20.9-1.60.0-0.60.7
Bone: cortical thickness0.20.41.40.40.20.1-1.00.3-0.80.1-0.10.8-1.2-0.4
Bone: cortical thickness1.21.43.51.9-1.1-1.3-0.11.80.21.6-0.9-0.3-1.21.0
Bone: cortical tissue density0.81.11.8-1.01.11.1-1.3-0.9-1.2-1.01.20.9-0.7-0.8
Condit. Reinf. active minus inactive responses0.50.61.1-0.00.50.7-0.7-0.7-0.9-0.9-0.81.1-0.1-1.0
Condit. Reinf. active-inactive response ratio1.21.32.3-0.71.01.2-1.2-1.2-1.3-1.40.71.2-0.4-1.5
Condit. Reinf. active responses0.70.92.2-0.80.81.1-0.4-1.5-0.6-1.4-0.51.00.6-0.9
Condit. Reinf. inactive responses0.30.41.3-0.80.20.40.6-1.10.4-0.7-0.3-0.01.20.2
Incentive salience index mean0.50.63.60.7-0.4-0.00.4-0.00.3-0.3-1.90.31.0-0.8
Condit. Reinf. lever presses1.62.16.11.3-1.3-0.91.70.91.80.7-2.5-0.92.0-0.2
Condit. Reinf. active minus inactive responses0.30.41.31.1-0.6-0.50.20.4-0.5-0.0-1.20.2-0.50.6
Condit. Reinf. active-inactive response ratio0.10.10.20.4-0.2-0.10.20.1-0.4-0.2-0.40.3-0.40.1
Condit. Reinf. active responses0.91.33.11.8-1.3-1.30.71.30.21.0-1.6-0.5-0.41.3
Condit. Reinf. inactive responses2.12.63.81.9-1.8-1.91.21.91.22.0-1.8-1.30.01.7
Condit. Reinf. lever presses0.50.61.10.9-0.9-1.00.80.70.50.9-0.4-0.8-0.11.0
Condit. Reinf. lever reinforcers received0.60.92.41.5-1.0-1.00.41.0-0.00.7-1.6-0.2-0.51.1
Conditioned reinforcement - actives0.30.31.7-0.2-0.20.10.7-0.50.4-0.8-0.4-0.21.3-0.3
Conditioned reinforcement - inactives0.30.41.30.7-0.8-0.60.60.50.50.3-0.3-0.30.31.1
Conditioned locomotion2.12.54.81.6-1.6-1.41.81.41.81.4-2.2-1.11.21.6
Patch foraging indifference point 0 sec0.10.10.5-0.20.30.4-0.2-0.2-0.2-0.3-0.70.7-0.1-0.3
Patch foraging indifference point AUC0.20.20.4-0.50.50.5-0.4-0.3-0.6-0.3-0.40.50.1-0.4
Delay disc. indifference point, 0s delay0.10.10.4-0.10.00.0-0.00.10.2-0.0-0.6-0.10.1-0.4
Delay disc. indifference point, 16s delay4.04.06.1-2.42.52.4-1.9-2.1-1.9-1.91.62.0-1.0-2.0
Delay disc. indifference point, 2s delay0.60.71.3-1.01.01.0-1.2-0.5-0.9-0.60.41.0-0.6-0.5
Delay disc. indifference point, 24s delay0.40.41.10.20.40.4-1.0-0.1-0.70.3-1.10.8-0.80.1
Delay disc. indifference point, 4s delay4.54.78.8-3.02.62.4-1.9-2.4-1.9-2.42.01.7-1.0-1.9
Delay disc. indifference point, 8s delay3.83.96.2-2.52.32.1-1.9-2.4-2.0-2.12.01.6-0.9-1.3
Indifference point function ln k2.12.94.62.1-2.2-2.02.01.71.91.6-1.1-1.81.01.1
Indifference point function log k2.12.94.62.1-2.2-2.02.01.71.91.6-1.1-1.81.01.1
Patch foraging total patch changes 0 sec0.10.20.6-0.50.60.7-0.3-0.5-0.4-0.5-0.30.8-0.1-0.4
Patch foraging total patch changes 12 sec0.00.00.2-0.00.0-0.0-0.10.4-0.30.3-0.30.2-0.20.0
Patch foraging total patch changes 18 sec0.50.61.7-0.70.91.0-0.5-0.8-0.6-0.9-0.40.90.3-1.3
Patch foraging total patch changes 24 sec0.10.10.5-0.70.20.20.0-0.50.00.00.1-0.10.40.1
Patch foraging total patch changes 6 sec0.50.81.4-1.11.21.1-0.9-0.7-0.9-0.4-0.51.1-0.5-0.9
Patch foraging time to switch 0 sec0.20.31.5-0.60.50.3-0.7-0.2-0.5-0.11.20.1-0.8-0.1
Patch foraging water rate 0 sec0.30.41.21.0-0.7-0.60.50.70.40.6-1.1-0.20.00.4
Patch foraging water rate 12 sec0.50.83.60.6-0.7-0.41.00.51.10.4-1.9-0.31.20.6
Patch foraging water rate 18 sec0.30.31.90.7-0.3-0.10.50.20.60.2-1.40.20.40.6
Patch foraging water rate 24 sec0.30.41.21.1-0.7-0.60.10.50.20.6-0.90.0-0.20.9
Patch foraging water rate 6 sec0.20.31.50.1-0.10.20.2-0.20.4-0.5-1.00.01.2-0.8
Seeking ratio, delayed vs. immediate footshock1.11.32.9-1.21.41.3-1.1-1.0-1.7-1.10.81.3-0.9-0.2
Distance traveled before self-admin0.40.41.0-0.1-0.7-0.61.00.20.70.10.0-1.01.00.6
Distance traveled after self-admin0.70.71.90.9-0.9-1.00.71.40.11.1-0.8-0.5-0.20.8
Extensor digitorum longus weight0.41.52.41.0-1.3-1.31.51.41.41.6-0.7-1.30.50.8
Bone: elastic displacement0.60.71.80.7-0.7-0.50.80.71.10.7-1.3-0.61.10.6
Bone: elastic work2.53.35.72.4-2.0-2.11.32.31.42.2-1.9-1.40.01.6
Bone: endosteal estimation1.94.05.82.2-2.3-2.42.11.92.02.4-1.5-2.20.71.7
Bone: endosteal perimeter2.75.68.12.8-2.8-2.72.42.32.32.7-2.4-2.31.21.3
Epididymis fat weight0.20.50.80.8-0.8-0.70.60.90.50.7-0.8-0.30.60.7
Delta time in closed arm before/after self-admin0.20.20.70.10.10.0-0.50.6-0.50.50.20.3-0.80.7
Delta time in open arm before/after self-admin0.70.72.7-0.4-0.4-0.31.2-0.11.1-0.30.7-1.11.6-0.1
Diff in mean of infusions in LGA sessions0.70.82.40.60.10.1-1.30.3-1.4-0.2-0.61.1-1.50.5
Delay discount exponential model param3.84.06.32.5-2.4-2.32.02.41.92.2-1.3-1.90.71.7
Extinction: sum of active levers before priming0.70.71.4-0.60.80.7-1.0-0.1-1.1-0.20.01.2-1.21.2
Active lever presses in extinction session 60.70.72.11.0-0.5-0.7-0.21.0-0.30.8-1.1-0.1-1.01.4
Bone: final force0.61.03.21.2-0.6-0.9-0.31.2-0.21.4-0.40.1-1.81.2
Bone: final moment0.81.33.81.3-0.7-1.0-0.31.4-0.11.6-0.60.0-2.01.4
Food consumed during 24 hour testing period4.04.811.03.3-2.6-2.51.82.61.82.2-2.7-1.60.31.2
Glucose0.50.71.60.60.30.5-1.1-0.2-1.2-0.9-0.71.2-0.8-1.0
Heart weight0.50.73.6-0.60.60.3-0.3-0.3-1.0-0.71.90.2-1.2-0.7
Delay discount hyperbolic model param3.53.76.02.4-2.3-2.21.92.31.82.1-1.3-1.80.71.6
Intermittent access intake day 1-15 change0.20.20.70.8-0.4-0.10.10.30.0-0.0-0.60.6-0.20.6
Intermittent access intake escalation0.40.41.21.1-0.7-0.50.50.60.40.4-0.70.20.01.1
Intermittent access intake escalation 20.50.52.00.70.20.4-0.80.5-0.50.1-0.81.4-1.00.2
Intermitt. access day 1 inactive lever presses0.40.42.10.5-0.2-0.5-0.80.5-0.90.10.00.1-1.50.4
Intermitt. access day 15 inactive lever presses1.71.84.52.1-1.3-1.30.21.60.11.5-1.8-0.2-1.01.9
Intermitt. access escalation Index0.20.20.50.3-0.4-0.40.60.60.50.7-0.2-0.40.20.4
Intermittent access day 1 total infusions2.42.84.01.6-2.0-1.72.01.21.81.2-1.3-1.71.81.7
Intermittent access day 15 total infusions2.12.43.92.0-2.0-1.61.71.31.51.2-1.2-1.11.21.9
Intermittent access terminal intake (last 3 days)3.53.87.02.6-2.4-2.01.91.91.81.6-2.1-1.21.12.1
Intermittent access total infusions3.23.55.82.4-2.3-2.01.91.81.81.6-1.8-1.51.32.0
Intermittent access day 1 locomotion1.31.33.51.0-1.4-1.11.40.31.30.3-0.9-1.31.90.9
Intermittent access day 15 total locomotion2.62.84.31.5-2.1-1.72.00.91.91.0-0.9-1.71.92.1
Intermittent access total locomotion2.12.45.01.8-1.9-1.71.41.21.51.1-1.3-1.31.22.2
Intermittent access standard deviation0.40.51.31.1-0.7-0.6-0.30.8-0.40.7-0.40.3-0.70.9
Left kidney weight9.727.442.05.8-6.2-6.54.96.15.06.1-3.6-5.71.44.1
Right kidney weight8.824.638.55.9-5.9-6.24.26.24.16.0-3.6-5.00.74.0
Cocaine induced anxiety1.11.32.81.4-1.0-1.2-0.31.3-0.21.7-1.1-0.4-1.31.4
Post-drug Anxiety1.21.46.40.9-0.2-0.6-1.30.9-1.41.3-0.60.6-2.50.6
Baseline Anxiety1.01.01.5-1.21.21.2-0.8-0.8-1.0-0.81.21.2-0.5-1.1
Tail length0.51.57.4-0.7-0.20.11.6-0.81.4-0.80.4-1.12.7-1.2
Length with tail0.52.05.51.0-1.5-1.11.80.71.90.7-1.2-1.52.3-0.4
Length without tail0.51.13.31.8-1.3-1.10.11.30.31.2-1.6-0.1-0.20.6
Times rat made contact with spout0.80.92.50.6-0.9-0.81.60.71.20.2-0.3-1.21.30.4
Lifetime Intake3.54.06.22.4-2.5-2.22.21.82.01.7-1.7-1.81.61.9
Liver weight, left0.20.20.50.4-0.5-0.60.40.70.30.5-0.4-0.4-0.30.6
Liver weight, right1.11.86.20.6-1.4-1.11.70.81.70.3-1.0-1.72.50.3
Locomotor activity3.35.37.12.3-2.6-2.42.72.12.62.0-2.4-2.42.11.2
Locomotor testing distance0.71.22.40.9-1.1-1.01.50.91.50.8-0.9-1.21.20.5
Locomotor testing rearing1.21.94.91.1-1.4-1.42.21.11.81.0-0.6-1.71.30.6
Locomotion in novel chamber1.41.75.9-0.8-0.10.11.7-0.71.8-0.60.5-1.32.4-1.7
Locomotion in novel chamber post-restriction0.10.10.5-0.50.2-0.0-0.00.40.10.30.7-0.2-0.30.5
Fecal boli incidents, locomotor time 10.10.10.2-0.2-0.2-0.30.40.10.00.4-0.3-0.50.30.1
Change in fecal boli incidents, locomotor task0.20.20.5-0.20.30.3-0.0-0.50.2-0.60.2-0.00.5-0.7
Time >=10cm from walls, locomotor time 10.30.31.20.1-0.3-0.50.30.70.41.10.1-0.7-0.30.7
Bouts of movement, locomotor time 10.40.51.90.9-0.6-0.60.20.50.20.5-1.20.0-0.31.4
Total resting periods, locomotor time 10.40.41.40.6-0.1-0.2-0.40.4-0.40.4-0.90.5-1.01.2
Rest time, locomotor task time 10.50.51.10.6-0.7-0.70.80.80.60.8-1.0-0.70.20.9
Distance moved, locomotor task time 10.10.10.20.2-0.3-0.40.10.00.20.3-0.0-0.40.1-0.2
Vertical activity count, locomotor time 10.20.20.50.10.20.2-0.50.1-0.50.4-0.10.4-0.7-0.7
Time >=10cm from walls, locomotor time 20.80.82.80.9-0.2-0.3-0.31.50.11.7-1.20.2-0.90.6
Bouts of movement, locomotor time 21.31.43.6-1.11.31.0-1.9-0.9-1.4-0.71.01.2-1.40.6
Total resting periods, locomotor time 21.51.63.3-1.21.31.1-1.8-1.0-1.5-0.90.91.4-1.40.7
Rest time, locomotor task time 21.82.04.7-2.01.31.50.4-2.10.3-2.2-0.00.51.6-1.4
Distance moved, locomotor task time 22.52.96.22.1-2.0-2.10.92.31.22.5-0.7-1.5-0.21.6
Vertical activity count, locomotor time 22.72.97.72.4-1.9-2.00.62.50.82.8-1.2-1.2-0.60.8
Light reinforcement 11.12.04.30.5-1.3-1.21.91.22.11.2-0.8-1.91.80.6
Light reinforcement 23.04.05.92.1-2.2-2.11.92.41.92.2-2.2-1.71.21.9
Bone: marrow area1.83.95.72.1-2.3-2.42.11.91.92.4-1.5-2.10.71.8
Bone: maximum diameter4.58.214.53.8-3.4-3.42.53.22.33.4-3.0-2.40.42.1
Bone: maximum force0.81.44.01.5-0.8-1.2-0.31.4-0.11.8-0.7-0.2-2.01.3
Bone: maximum moment1.01.84.71.7-1.0-1.3-0.21.6-0.02.0-0.9-0.2-2.21.5
Mean time between licks in bursts0.50.72.5-1.11.01.0-0.2-1.00.0-0.80.60.40.4-1.6
Mean num. licks in bursts0.81.01.81.3-1.2-1.30.51.40.51.1-0.8-0.8-0.51.1
Cd content in liver0.40.40.9-0.40.60.6-0.9-0.4-0.8-0.50.40.9-0.70.2
Co content in liver0.91.01.41.2-1.1-1.01.21.21.10.8-1.0-1.00.90.1
Cu content in liver5.87.012.9-3.63.33.1-2.5-3.2-2.3-2.52.62.4-1.2-1.4
Fe content in liver0.30.32.20.8-0.3-0.2-0.10.60.10.3-1.50.3-0.20.3
K content in liver0.40.41.60.00.40.2-1.3-0.2-0.80.2-0.40.8-1.10.2
Mg content in liver0.70.72.0-0.10.60.5-1.4-0.5-1.0-0.1-0.41.2-1.30.4
Mn content in liver1.31.52.41.0-1.4-1.21.21.01.61.3-1.1-1.41.50.4
Na content in liver2.93.14.6-1.62.01.9-2.1-1.9-1.9-1.71.01.8-1.2-1.7
Rb content in liver0.80.92.3-0.81.10.9-1.3-0.7-1.1-0.20.71.2-1.5-0.2
Se content in liver0.10.10.5-0.20.00.20.2-0.40.4-0.2-0.40.10.70.2
Sr content in liver0.80.71.8-1.20.40.50.6-1.00.4-1.01.1-0.41.3-0.5
Zn content in liver0.60.71.5-1.10.90.9-0.3-1.1-0.3-1.01.20.40.3-1.0
Bone: minimum diameter1.42.74.22.0-2.0-1.91.81.41.61.6-1.7-1.61.10.7
Time in familiar zone, hab. session 11.21.11.91.0-1.0-1.11.21.41.21.3-1.1-1.00.21.0
Time in novel zone, hab. session 10.30.31.10.10.30.3-0.5-0.4-0.6-0.30.70.4-0.5-1.0
Total zone transitions, hab. session 11.72.45.6-1.81.71.6-1.4-2.4-1.2-1.41.91.2-0.6-1.2
Total locomotion distance, hab. session 10.20.20.6-0.4-0.1-0.10.1-0.60.70.10.8-0.60.7-0.4
Locomotion velocity, hab. session 10.20.31.0-0.4-0.2-0.10.2-0.50.80.10.5-0.71.0-0.3
Time in familiar zone, hab. session 20.30.31.20.0-0.4-0.20.80.20.90.2-0.5-0.41.1-0.4
Time in novel zone, hab. session 20.70.71.3-0.20.80.7-1.1-0.4-1.2-0.90.80.8-1.1-0.6
Total zone transitions, hab. session 20.20.20.90.2-0.1-0.3-0.3-0.0-0.00.7-0.10.0-1.01.0
Total locomotion distance, hab. session 20.10.10.40.3-0.3-0.4-0.00.30.30.5-0.3-0.2-0.10.6
Locomotion velocity, hab. session 20.10.10.30.2-0.3-0.3-0.00.20.30.4-0.4-0.2-0.00.5
Novel to familiar place preference ratio0.30.31.7-0.30.40.30.20.00.0-0.31.0-0.2-0.1-1.3
Novelty place preference0.30.31.70.00.0-0.10.60.30.40.01.0-0.60.3-1.3
Time in novel zone, NPP test0.40.52.4-0.10.1-0.00.60.30.5-0.01.2-0.60.2-1.6
Total zone transitions, NPP test0.91.22.8-1.71.31.2-1.0-1.3-1.0-1.01.20.9-0.6-0.3
Total locomotion distance, NPP test0.10.20.7-0.80.40.4-0.4-0.4-0.2-0.40.40.10.10.7
Locomotion velocity, NPP test0.20.31.0-1.00.50.4-0.3-0.6-0.2-0.40.20.20.30.8
Intraocular pressure0.91.23.90.6-1.0-0.71.40.21.50.2-1.2-1.12.00.7
Delta distance traveled before/after self-admin0.40.51.10.7-0.7-0.70.81.00.40.8-0.7-0.70.2-0.1
Delta ambulatory time before/after self-admin0.30.41.00.7-0.4-0.50.51.00.21.0-0.8-0.3-0.10.2
Parametrial fat weight0.30.62.2-1.20.40.60.7-0.90.6-0.8-0.5-0.21.5-0.2
Pavlov. Cond. lever latency0.91.14.9-1.20.90.5-1.2-0.6-1.2-0.22.20.3-1.30.2
Pavlov. Cond. magazine entry latency0.50.72.70.30.50.7-0.50.1-0.6-0.8-1.61.3-0.4-1.0
Pavlov. Cond. change in total contacts0.80.86.01.2-0.00.3-0.20.3-0.4-0.2-2.51.1-0.3-0.1
Pavlov. Cond. index score0.50.64.80.9-0.20.10.10.40.1-0.2-2.20.70.2-0.5
Pavlov. Cond. latency score0.50.74.61.1-0.4-0.20.40.60.4-0.0-2.10.40.4-0.4
Pavlov. Cond. lever contacts1.61.97.91.5-1.2-0.71.40.91.50.4-2.8-0.41.7-0.2
Pavlov. Cond. magazine entry number0.50.63.2-0.5-0.3-0.60.4-0.20.50.61.8-1.20.20.7
Pavlov. Cond. intertrial magazine entries1.01.22.3-1.01.21.3-1.2-1.5-1.1-1.10.31.3-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.50.64.40.8-0.10.30.10.20.1-0.4-2.10.80.4-0.7
Pavlov. Cond. response bias0.91.08.11.0-0.40.10.60.60.5-0.2-2.80.60.9-0.2
Pavlov. Cond. lever latency0.10.20.5-0.60.50.5-0.4-0.3-0.1-0.50.40.20.2-0.7
Pavlov. Cond. magazine entry latency2.32.65.8-1.11.61.4-2.1-1.3-2.3-1.11.01.9-2.40.2
Pavlov. Cond. change in total contacts0.60.83.50.80.20.0-0.90.0-1.4-0.1-0.40.9-1.90.7
Pavlov. Cond. index score0.50.62.3-0.10.50.4-0.9-0.5-1.2-0.30.30.9-1.50.5
Pavlov. Cond. latency score0.50.62.70.00.50.3-0.9-0.4-1.3-0.20.30.9-1.70.7
Pavlov. Cond. lever contacts0.30.41.40.8-0.4-0.5-0.00.4-0.20.7-0.40.0-0.91.2
Pavlov. Cond. magazine entry number0.91.12.80.5-0.8-0.61.30.81.60.6-1.2-0.91.7-0.5
Pavlov. Cond. intertrial magazine entries0.40.51.40.9-0.6-0.7-0.10.90.10.9-1.2-0.0-0.70.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.7-0.20.50.4-0.8-0.6-1.1-0.40.50.8-1.30.5
Pavlov. Cond. response bias0.30.41.70.30.10.0-0.5-0.1-0.80.2-0.00.6-1.30.9
Time in closed arm before self-admin1.01.23.3-0.11.01.1-1.6-1.0-1.2-0.5-0.21.8-1.3-0.6
Time in closed arm after self-admin0.10.10.40.4-0.00.0-0.30.20.10.6-0.20.3-0.30.1
Time in open arm before self-admin0.60.61.6-1.20.1-0.00.8-0.70.6-0.60.9-1.11.3-0.1
Time in open arm after self-admin0.40.51.5-1.20.2-0.00.3-0.50.0-0.81.2-0.90.80.2
Bone: periosteal estimation1.93.96.32.5-2.3-2.41.72.21.62.5-1.8-1.80.21.4
Bone: periosteal perimeter3.66.09.53.1-2.9-2.72.42.52.22.6-3.0-2.21.31.2
Bone: post-yield work0.70.92.8-0.61.10.8-1.0-0.6-1.4-0.50.61.0-1.7-0.1
Progressive ratio test 1 active lever presses2.12.25.50.8-1.4-1.01.90.42.00.4-1.4-1.52.31.6
Progressive ratio test 1 breakpoint1.92.05.30.7-1.3-1.01.90.31.90.3-1.5-1.42.31.6
Progressive ratio test 1 inactive lever presses0.60.71.80.2-0.9-0.91.00.40.60.30.3-1.31.10.9
Progressive ratio test 2 active lever presses0.30.31.80.9-0.6-0.5-0.40.3-0.30.0-0.5-0.00.11.3
Progressive ratio test 2 breakpoint0.30.31.80.8-0.6-0.5-0.40.4-0.30.1-0.4-0.0-0.01.3
Progressive ratio test 2 inactive lever presses0.81.04.41.2-1.2-1.10.11.00.20.9-0.3-0.50.02.1
Incentive Sensitization - Responses0.60.61.81.0-0.4-0.4-1.00.6-0.90.3-0.10.4-1.01.3
Incentive Sensitization - Breakpoint0.60.61.91.1-0.5-0.5-0.90.7-0.70.4-0.20.2-1.01.4
Sum of active levers in priming session hrs 5-60.50.41.80.40.10.0-0.90.2-1.1-0.10.00.6-1.30.8
Progressive ratio0.20.21.0-0.60.50.6-0.1-0.6-0.4-1.00.10.40.3-0.1
Food seeking constrained by brief footshock0.50.61.31.0-0.8-0.90.51.10.31.0-0.8-0.6-0.20.9
Seeking ratio, punishment vs. effort0.60.72.21.0-0.6-0.9-0.21.2-0.11.5-0.2-0.2-1.30.7
Retroperitoneal fat weight2.16.99.52.7-3.1-2.92.72.62.62.6-2.7-2.51.82.6
Reaction time number correct0.20.30.7-0.60.50.6-0.1-0.8-0.1-0.80.10.20.4-0.6
Reaction time mean minus median0.20.30.8-0.50.60.6-0.5-0.8-0.1-0.90.00.40.4-0.5
Reaction time mean minus median AUC0.20.30.9-0.70.20.10.0-0.90.3-0.90.3-0.61.0-0.1
Reaction time num false alarms0.30.52.40.3-0.4-0.21.0-0.31.0-0.1-0.5-0.51.5-0.2
Reaction time num false alarms AUC0.40.63.30.2-0.6-0.21.1-0.31.1-0.1-0.2-0.61.8-0.4
Reaction time trials correct on left0.20.30.7-0.60.50.6-0.1-0.8-0.1-0.80.10.20.4-0.6
Reaction time trials on left0.20.30.7-0.60.50.6-0.2-0.8-0.1-0.80.10.20.4-0.6
Reaction time mean2.23.15.8-1.51.91.8-2.4-1.8-2.1-1.71.51.9-1.6-0.3
Reaction time mean AUC2.43.35.3-1.72.01.9-2.3-2.1-2.0-1.81.71.8-1.5-0.4
Median of all reaction times3.04.17.7-1.72.22.0-2.8-2.0-2.4-1.71.72.3-2.1-0.3
Reaction time omissions1.11.52.4-1.21.61.5-1.5-1.1-1.3-1.20.81.5-1.0-0.3
Reaction time false alarm rate0.40.51.80.6-0.8-0.61.00.21.00.4-0.3-0.71.30.1
Reaction time premature initiation rate0.70.94.21.0-0.2-0.4-1.10.8-1.10.8-0.30.7-2.10.7
Reaction time premature initiations0.40.62.80.50.20.1-1.20.1-1.20.2-0.10.8-1.70.2
Std. dev. reaction times0.71.01.6-1.01.11.1-1.3-1.2-0.9-1.20.80.9-0.2-0.4
Reaction time trials completed0.20.30.7-0.60.50.6-0.2-0.8-0.1-0.80.10.20.4-0.6
Reaction time trials AUC0.10.10.3-0.30.30.3-0.0-0.50.0-0.6-0.10.10.4-0.3
Run reversals in cocaine runway, females0.40.41.4-0.20.10.30.8-0.41.0-0.20.0-0.21.2-0.8
Run reversals in cocaine runway, males1.41.43.90.7-1.1-0.81.70.41.70.3-1.0-1.42.00.3
Latency to leave start box in cocaine runway1.61.72.61.5-1.6-1.61.11.21.21.3-1.0-1.30.51.4
Latency to leave start box in cocaine runway, F0.80.91.41.0-1.1-1.11.01.01.21.0-0.5-1.10.40.9
Latency to leave start box in cocaine runway, M1.41.32.61.6-1.5-1.50.80.90.61.1-1.2-0.90.21.4
Std. dev. time between licks in bursts0.30.41.3-0.20.60.5-0.80.4-0.50.1-0.30.8-1.1-0.4
Total sessions with >9 infusions3.94.37.72.1-2.4-2.02.81.82.51.8-1.7-2.12.11.2
Short access day 1 total inactive lever presses3.03.45.81.9-2.1-2.02.11.81.71.9-1.3-1.80.72.4
Short access day 10 total inactive lever presses0.40.51.40.9-0.5-0.6-0.20.9-0.30.7-1.20.0-0.80.5
Short access day 1 total infusions3.03.26.21.9-2.1-1.92.51.12.21.2-0.9-2.11.81.0
Short access day 10 total infusions3.94.36.22.2-2.3-1.92.41.72.31.8-2.5-1.71.82.0
Short access total infusions5.05.68.02.7-2.8-2.62.72.22.42.2-2.1-2.31.62.1
Short access day 1 locomotion0.30.31.00.8-0.6-0.50.50.30.50.4-0.3-0.30.21.0
Short access day 10 total locomotion1.51.64.80.1-0.9-0.71.70.22.00.3-0.3-1.52.21.6
Short access total locomotion2.12.24.11.5-1.6-1.51.61.41.41.5-1.3-1.41.02.0
One hour access (0.3 mA shock)0.70.81.31.1-1.2-1.00.90.80.80.7-0.2-1.00.90.7
Compulsive drug intake1.11.12.7-0.71.00.8-1.4-0.3-1.5-0.21.50.9-1.7-0.6
One hour access (shock baseline)2.12.43.31.7-1.8-1.51.81.21.81.0-1.5-1.41.81.4
Social response proportion1.21.32.81.7-1.3-1.21.11.60.91.1-1.1-0.90.2-0.1
Social responses2.12.74.51.5-1.7-1.62.11.52.11.5-1.4-1.81.60.8
Social time0.40.51.7-0.30.30.60.5-0.30.8-0.5-0.70.21.3-1.3
Soleus weight0.20.51.40.7-0.5-0.5-0.00.60.10.8-1.20.1-0.61.2
Bone: stiffness1.42.211.50.10.90.4-2.0-0.1-2.10.10.81.5-3.40.2
Tibialis anterior weight0.20.52.2-0.80.70.5-0.3-0.7-0.6-0.01.50.3-0.9-0.5
Time to tail flick, vehicle, before self-admin0.20.30.6-0.50.10.20.4-0.70.2-0.60.2-0.40.8-0.7
Time to tail flick, vehicle, after self-admin0.20.30.60.7-0.6-0.30.70.20.50.4-0.8-0.10.5-0.1
Time to tail flick, test, before self-admin2.12.13.81.4-1.6-1.41.91.11.91.1-1.3-1.51.60.0
Time to tail flick, test, after self-admin0.70.72.20.70.50.6-1.10.3-0.60.4-0.61.5-1.30.8
Delta time to tail flick, vehicle, before/after SA0.40.40.91.0-0.4-0.5-0.20.8-0.40.9-0.60.2-0.90.6
Delta time to tail flick, test, before/after SA3.33.06.7-0.81.81.8-2.6-1.1-2.2-1.00.72.5-2.2-0.1
Tibia length0.10.32.10.8-0.4-0.30.10.40.20.4-1.50.3-0.10.1
Ambulatory time before self-admin0.40.41.0-0.4-0.5-0.50.90.00.6-0.10.4-1.01.00.4
Ambulatory time after self-admin0.20.20.70.3-0.2-0.20.20.9-0.30.7-0.30.1-0.40.2
Bone: tissue strength1.00.93.2-0.51.00.8-1.4-0.5-1.1-0.1-0.11.2-1.80.4
Total heroin consumption0.50.52.10.4-0.1-0.3-0.80.5-1.00.4-0.40.3-1.41.0
Bone: trabecular number0.50.71.3-0.90.91.1-0.3-1.1-0.2-1.20.40.80.4-1.0
Bone: trabecular spacing2.63.35.01.9-2.0-2.21.71.91.32.2-1.5-1.90.32.1
Bone: trabecular thickness0.10.20.4-0.20.30.4-0.5-0.4-0.2-0.50.60.30.2-0.3
Bone: trabecular tissue density1.52.13.4-1.31.51.3-1.7-1.3-1.8-1.31.71.4-1.6-0.5
Water consumed over 24 hours1.92.35.12.3-1.8-1.81.41.81.41.5-1.6-1.30.30.2
Number of responses in last shaping day0.10.10.30.4-0.3-0.20.60.30.50.3-0.2-0.40.40.2