Hub : Genes

Tspan13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tspan13 0.2 0.09 0.0e+00 0.2 0.17 0.18 0.19 2.2e-21 9.2e-19 1.7e-19 3.0e-20
2 IC gene expression Tspan13 0.3 0.11 3.3e-11 0.18 0.23 0.22 0.06 3.8e-08 7.4e-10 1.2e-09 1.5e-03
3 OFC gene expression Tspan13 0.36 0.14 4.4e-08 0.27 0.31 0.31 0.31 5.0e-07 4.6e-08 4.0e-08 3.8e-08
4 Adipose gene expression Tspan13 0.39 0.13 0.0e+00 0.32 0.35 0.36 0.34 8.5e-37 1.9e-40 2.4e-41 2.0e-39
5 Brain mRNA stability Tspan13 0.11 0.06 5.2e-06 0.04 0.06 0.06 0.06 5.0e-05 4.9e-06 2.9e-06 2.7e-06
6 LHb mRNA stability Tspan13 0.15 0.1 4.5e-03 0.04 0.05 0.01 0.03 3.4e-02 2.5e-02 1.8e-01 6.0e-02
7 Brain gene expression Tspan13 0.2 0.1 6.5e-13 0.13 0.14 0.13 0.12 3.1e-12 3.4e-13 1.8e-12 2.4e-11
8 pVTA gene expression Tspan13 0.05 0.03 3.9e-04 0.01 0.04 0.03 0.03 2.8e-02 1.7e-04 1.5e-03 3.0e-03
9 IL gene expression Tspan13 0.46 0.18 6.7e-05 0.16 0.18 0.16 0.16 9.0e-05 3.5e-05 1.4e-04 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.84.87.9-2.1-1.5-2.4-2.4-2.8-2.5-2.41.3-1.6
Area under the delay curve0.40.41.1-0.1-0.8-0.2-0.20.41.10.90.9-0.4
BMI with tail0.62.27.9-0.51.6-0.2-0.4-0.3-2.8-2.5-1.60.2
BMI without tail0.41.32.3-1.5-0.9-1.4-1.3-0.8-0.5-0.61.0-1.5
Body weight0.10.62.0-1.00.2-0.6-0.4-0.7-1.2-1.4-0.4-0.1
Weight adjusted by age1.72.64.41.61.62.11.82.01.11.1-1.51.5
Bone surface2.13.75.4-2.0-1.3-2.2-2.1-2.3-2.2-2.31.1-1.5
Bone volume2.34.26.4-1.8-1.6-2.5-2.5-2.5-1.9-1.81.6-1.8
Breakpoint value in progressive ratio session0.60.72.4-1.2-0.4-0.7-0.5-0.8-1.1-1.5-0.00.0
Number of licking bursts1.52.43.61.91.51.71.71.71.11.3-1.31.4
Context. condit. distance diff. score0.10.10.5-0.4-0.1-0.1-0.1-0.4-0.6-0.7-0.20.3
Locomotion velocity, session 10.00.00.1-0.0-0.2-0.3-0.2-0.00.10.30.3-0.3
Locomotion distance, session 10.30.30.6-0.6-0.7-0.8-0.8-0.5-0.3-0.10.7-0.4
Locomotion velocity, session 20.20.20.5-0.6-0.7-0.5-0.2-0.20.30.20.6-0.3
Locomotion distance, session 21.41.93.2-1.2-1.6-1.8-1.7-1.4-0.4-0.31.6-1.4
Locomotion velocity, session 30.10.20.80.90.30.10.1-0.20.30.6-0.00.1
Locomotion distance, session 32.93.16.8-1.3-1.1-1.9-2.2-2.6-1.8-1.81.1-1.5
Stereotopy head waving bouts, day 31.41.64.30.90.91.21.42.11.51.4-0.80.8
Stereotopy head waving duration, day 32.63.16.11.51.41.92.02.51.91.8-1.11.1
Locomotion velocity, session 70.91.01.9-0.9-1.0-1.1-1.1-1.4-0.9-0.90.9-0.6
Locomotion distance, session 71.41.73.1-1.0-0.9-1.5-1.5-1.8-1.5-1.30.8-1.0
Stereotopy head waving bouts, day 71.31.53.40.90.21.01.11.71.81.8-0.11.1
Stereotopy head waving duration, day 72.22.65.61.40.51.41.52.12.32.4-0.31.3
Locomotion velocity, session 80.10.10.50.3-0.20.30.10.10.70.60.3-0.1
Locomotion distance, session 81.31.82.6-1.5-1.5-1.6-1.6-1.6-0.7-0.91.3-1.1
Degree of sensitization distance0.10.10.5-0.1-0.00.20.40.70.40.2-0.10.1
Degree of sensitization stereotypy1.71.84.31.00.11.11.11.72.12.10.01.2
Conditioned locomotion1.92.27.11.70.51.01.01.42.42.70.1-0.1
Cocaine response after cond. corrected0.30.40.70.50.60.70.60.90.40.3-0.60.8
Cocaine response after cond. not corrected0.10.10.40.20.40.30.20.4-0.2-0.1-0.40.7
Cocaine response before conditioning0.81.01.8-0.7-0.8-1.2-1.4-1.2-0.9-0.70.9-0.8
Saline control response6.08.011.6-3.3-3.4-3.3-3.1-2.9-0.8-1.33.2-2.8
Bone: connectivity density2.84.410.9-2.3-0.9-1.8-1.6-2.5-3.2-3.30.3-0.8
Bone: cortical apparent density0.40.51.51.20.90.80.70.2-0.00.3-0.70.7
Bone: cortical area0.20.40.7-0.1-0.6-0.5-0.7-0.30.50.50.8-0.9
Bone: cortical porosity0.30.41.30.70.10.20.10.41.01.10.2-0.2
Bone: cortical porosity0.50.52.00.80.10.30.20.71.31.40.3-0.1
Bone: cortical thickness0.10.10.40.70.20.3-0.00.10.50.60.1-0.1
Bone: cortical thickness1.01.22.21.50.91.20.91.41.11.3-0.60.8
Bone: cortical tissue density0.40.51.41.20.90.80.70.2-0.10.2-0.80.7
Condit. Reinf. active minus inactive responses5.96.610.0-2.9-2.6-2.9-2.8-3.2-1.5-1.92.3-2.5
Condit. Reinf. active-inactive response ratio5.25.68.7-2.8-2.5-2.6-2.4-3.0-1.6-2.02.1-2.1
Condit. Reinf. active responses4.15.16.9-2.4-2.4-2.6-2.5-2.6-0.9-1.32.3-2.5
Condit. Reinf. inactive responses0.20.20.4-0.3-0.4-0.4-0.50.10.40.30.6-0.6
Incentive salience index mean6.17.59.8-3.1-3.1-3.1-3.0-3.1-0.9-1.52.8-2.9
Condit. Reinf. lever presses1.92.64.4-1.8-2.1-1.8-1.8-1.60.2-0.32.0-1.8
Condit. Reinf. active minus inactive responses0.60.71.8-1.3-1.2-0.9-0.8-0.7-0.1-0.40.9-0.8
Condit. Reinf. active-inactive response ratio0.20.30.70.00.10.50.60.80.90.6-0.30.3
Condit. Reinf. active responses2.12.94.0-2.0-1.9-1.9-2.0-1.7-0.4-0.81.8-1.9
Condit. Reinf. inactive responses2.63.35.7-1.7-1.8-2.1-2.4-1.9-0.6-0.72.0-2.3
Condit. Reinf. lever presses1.82.53.8-1.9-1.6-1.8-1.7-1.8-0.9-1.21.5-1.4
Condit. Reinf. lever reinforcers received2.94.05.9-2.4-2.3-2.2-2.3-2.1-0.7-1.12.1-2.1
Conditioned reinforcement - actives0.10.20.60.1-0.10.40.40.70.50.3-0.10.4
Conditioned reinforcement - inactives1.52.25.0-1.2-2.2-1.0-1.1-0.21.71.22.2-1.5
Conditioned locomotion0.30.40.90.90.10.60.50.80.81.00.10.2
Patch foraging indifference point 0 sec2.24.19.3-3.1-2.7-2.3-1.9-1.4-0.4-1.22.1-1.7
Patch foraging indifference point AUC2.13.04.7-1.7-0.8-1.8-2.1-2.2-1.6-1.90.9-2.2
Delay disc. indifference point, 0s delay0.40.41.20.60.10.50.60.91.11.10.1-0.0
Delay disc. indifference point, 16s delay1.01.12.9-1.4-1.7-1.1-1.1-0.60.3-0.21.3-0.6
Delay disc. indifference point, 2s delay0.60.71.61.30.60.80.70.90.81.2-0.20.4
Delay disc. indifference point, 24s delay0.70.71.8-0.7-1.3-0.4-0.50.41.30.81.1-0.5
Delay disc. indifference point, 4s delay0.20.30.60.00.2-0.3-0.5-0.6-0.8-0.6-0.0-0.7
Delay disc. indifference point, 8s delay0.50.61.6-0.4-1.2-0.6-0.6-0.00.70.61.3-0.7
Indifference point function ln k0.40.71.30.5-0.10.60.91.11.01.1-0.01.2
Indifference point function log k0.40.71.30.5-0.10.60.91.11.01.1-0.01.2
Patch foraging total patch changes 0 sec2.03.88.9-3.0-2.6-2.2-1.9-1.3-0.3-1.12.1-1.7
Patch foraging total patch changes 12 sec4.35.610.1-3.0-1.3-2.3-2.5-2.5-2.7-3.20.9-1.9
Patch foraging total patch changes 18 sec1.62.54.5-1.9-1.3-1.7-2.0-1.5-0.7-1.11.3-2.1
Patch foraging total patch changes 24 sec0.20.41.5-1.2-0.9-0.4-0.3-0.20.2-0.40.6-0.4
Patch foraging total patch changes 6 sec3.95.911.1-3.3-2.5-2.7-2.7-2.2-1.4-2.02.1-2.5
Patch foraging time to switch 0 sec0.71.53.41.91.61.40.90.9-0.00.6-1.31.2
Patch foraging water rate 0 sec0.20.51.3-1.2-0.7-0.8-0.5-0.5-0.4-0.80.5-0.5
Patch foraging water rate 12 sec0.61.23.2-1.1-1.8-1.2-0.7-0.10.90.71.7-0.8
Patch foraging water rate 18 sec0.10.20.5-0.6-0.7-0.4-0.2-0.00.20.10.50.0
Patch foraging water rate 24 sec0.70.91.6-1.3-0.6-0.9-1.1-1.0-1.1-1.10.5-0.8
Patch foraging water rate 6 sec0.00.00.2-0.2-0.4-0.2-0.00.20.20.10.2-0.1
Seeking ratio, delayed vs. immediate footshock0.91.13.30.71.20.20.4-0.6-1.8-1.2-1.11.1
Distance traveled before self-admin0.40.51.1-0.0-1.0-0.3-0.4-0.00.90.91.1-0.1
Distance traveled after self-admin1.92.34.2-1.6-2.0-1.5-1.7-1.8-0.2-0.61.8-1.4
Extensor digitorum longus weight2.610.320.7-3.4-4.5-3.3-2.9-1.52.11.34.5-3.5
Bone: elastic displacement0.40.40.90.10.80.50.50.0-0.9-0.9-0.90.4
Bone: elastic work0.00.00.1-0.3-0.00.00.00.0-0.2-0.3-0.0-0.0
Bone: endosteal estimation0.40.91.5-1.0-0.7-1.2-1.2-0.9-0.8-0.80.7-1.0
Bone: endosteal perimeter0.30.71.3-1.1-0.8-1.0-0.8-0.7-0.5-0.70.7-0.8
Epididymis fat weight1.34.511.10.93.01.31.40.2-2.6-2.4-3.31.9
Delta time in closed arm before/after self-admin1.11.02.31.51.21.21.00.80.60.9-0.90.6
Delta time in open arm before/after self-admin1.91.94.2-1.8-2.0-1.7-1.5-0.8-0.0-0.31.7-0.9
Diff in mean of infusions in LGA sessions0.40.51.0-0.6-0.4-0.8-0.7-1.0-1.0-0.90.2-0.4
Delay discount exponential model param0.40.41.00.00.70.10.2-0.4-1.0-0.9-0.90.4
Extinction: sum of active levers before priming0.10.10.5-0.40.00.10.10.0-0.4-0.7-0.30.2
Active lever presses in extinction session 60.30.30.8-0.40.0-0.4-0.4-0.8-0.9-0.9-0.1-0.1
Bone: final force0.50.81.91.00.30.70.71.11.21.4-0.10.9
Bone: final moment0.30.51.50.7-0.10.40.40.71.11.20.30.5
Food consumed during 24 hour testing period0.10.10.20.50.5-0.1-0.3-0.1-0.3-0.1-0.2-0.4
Glucose0.40.61.30.91.10.70.8-0.1-0.7-0.6-1.00.5
Heart weight0.30.41.50.2-0.50.10.10.21.21.20.60.2
Delay discount hyperbolic model param0.30.30.8-0.20.50.10.2-0.3-0.9-0.9-0.70.4
Intermittent access intake day 1-15 change0.40.81.5-1.1-1.0-1.1-1.2-0.5-0.3-0.50.9-1.1
Intermittent access intake escalation0.40.81.4-1.1-0.8-1.1-1.2-0.8-0.7-0.80.7-0.8
Intermittent access intake escalation 20.10.10.2-0.0-0.3-0.2-0.10.30.40.30.3-0.1
Intermitt. access day 1 inactive lever presses0.62.34.31.50.81.41.52.11.92.0-0.51.1
Intermitt. access day 15 inactive lever presses0.20.40.90.60.60.70.70.80.20.3-0.71.0
Intermitt. access escalation Index0.30.41.20.81.10.20.1-0.6-0.9-0.5-0.80.0
Intermittent access day 1 total infusions2.03.35.01.91.42.12.22.01.21.3-1.42.2
Intermittent access day 15 total infusions0.20.30.70.60.40.60.60.80.30.4-0.40.8
Intermittent access terminal intake (last 3 days)1.62.13.91.50.91.61.62.01.41.4-0.91.4
Intermittent access total infusions1.31.62.51.20.81.51.51.60.91.0-0.91.5
Intermittent access day 1 locomotion0.91.12.11.00.41.11.21.51.21.2-0.41.0
Intermittent access day 15 total locomotion0.20.41.2-0.1-0.8-0.1-0.10.61.11.00.8-0.1
Intermittent access total locomotion0.70.81.80.6-0.20.70.81.41.31.30.20.9
Intermittent access standard deviation0.10.20.50.70.30.40.40.60.00.3-0.30.7
Left kidney weight0.52.14.0-1.5-0.9-1.5-1.5-2.0-1.7-1.80.7-1.0
Right kidney weight0.10.30.9-0.30.0-0.4-0.4-0.9-0.7-0.7-0.1-0.2
Cocaine induced anxiety1.31.94.31.30.31.31.31.72.12.0-0.10.7
Post-drug Anxiety0.50.61.90.1-0.80.20.30.51.41.20.80.2
Baseline Anxiety2.02.45.1-1.5-0.8-1.5-1.4-2.3-2.1-2.00.6-0.7
Tail length1.03.98.5-1.9-2.9-2.0-1.5-1.51.50.72.8-2.1
Length with tail0.31.22.7-0.9-1.7-0.9-0.3-0.71.50.81.5-0.7
Length without tail0.82.74.91.71.81.92.01.20.40.4-2.02.2
Times rat made contact with spout1.11.22.91.61.70.90.90.2-0.8-0.3-1.51.0
Lifetime Intake0.81.01.70.90.51.11.21.30.70.8-0.61.3
Liver weight, left0.50.92.7-1.00.1-0.6-0.8-0.7-1.4-1.7-0.2-0.9
Liver weight, right0.91.53.21.31.81.31.10.0-0.8-0.6-1.81.4
Locomotor activity6.910.815.7-4.0-3.2-3.7-3.7-3.7-2.2-2.62.9-3.3
Locomotor testing distance4.58.010.5-3.2-2.7-3.2-3.2-3.2-1.7-2.02.6-3.1
Locomotor testing rearing4.38.611.7-3.3-2.9-3.4-3.4-3.3-2.0-2.12.7-2.9
Locomotion in novel chamber0.10.20.6-0.5-0.1-0.1-0.2-0.5-0.8-0.7-0.00.0
Locomotion in novel chamber post-restriction0.30.41.10.40.90.60.60.1-0.5-0.4-1.00.8
Fecal boli incidents, locomotor time 10.40.51.40.3-0.5-0.5-0.70.20.81.21.0-0.7
Change in fecal boli incidents, locomotor task0.10.10.1-0.00.10.30.30.00.1-0.2-0.40.3
Time >=10cm from walls, locomotor time 10.70.72.10.4-0.40.40.80.71.51.40.30.6
Bouts of movement, locomotor time 11.71.93.91.80.61.31.11.51.92.0-0.30.7
Total resting periods, locomotor time 11.82.03.92.00.71.41.21.51.92.0-0.40.7
Rest time, locomotor task time 10.70.92.91.0-0.10.70.50.91.61.70.4-0.0
Distance moved, locomotor task time 10.10.10.4-0.20.50.30.30.2-0.3-0.3-0.60.5
Vertical activity count, locomotor time 10.00.10.2-0.00.30.30.20.50.30.2-0.30.2
Time >=10cm from walls, locomotor time 20.40.62.20.6-0.4-0.20.00.31.21.50.8-0.5
Bouts of movement, locomotor time 20.10.10.4-0.2-0.2-0.00.10.60.60.20.00.1
Total resting periods, locomotor time 20.10.10.5-0.1-0.20.10.10.70.70.30.00.1
Rest time, locomotor task time 20.50.61.00.90.70.90.81.00.70.8-0.50.6
Distance moved, locomotor task time 20.10.10.2-0.3-0.1-0.2-0.4-0.4-0.3-0.30.1-0.2
Vertical activity count, locomotor time 20.10.10.2-0.3-0.4-0.3-0.3-0.30.20.20.4-0.2
Light reinforcement 10.20.51.2-0.8-1.1-0.7-0.6-0.7-0.1-0.30.9-0.5
Light reinforcement 20.10.20.7-0.6-0.8-0.3-0.1-0.50.40.10.6-0.3
Bone: marrow area0.51.01.7-1.1-0.8-1.3-1.3-0.9-0.8-0.80.8-1.0
Bone: maximum diameter0.30.51.0-0.5-0.9-0.6-0.6-0.00.80.71.0-0.9
Bone: maximum force0.20.41.10.1-0.6-0.3-0.30.31.01.00.8-0.0
Bone: maximum moment0.30.51.3-0.2-0.9-0.7-0.70.00.90.91.1-0.4
Mean time between licks in bursts0.20.41.70.0-0.20.10.21.31.01.00.2-0.0
Mean num. licks in bursts1.62.54.2-1.4-0.7-1.6-1.7-2.1-2.0-1.90.7-1.3
Cd content in liver0.60.62.3-1.0-0.2-0.3-0.3-0.7-1.3-1.5-0.20.1
Co content in liver1.01.12.3-1.5-1.3-1.2-0.9-1.0-0.4-0.81.0-1.1
Cu content in liver1.21.52.70.91.41.41.41.0-0.3-0.3-1.61.6
Fe content in liver2.32.85.61.72.21.81.90.7-0.9-0.7-2.41.8
K content in liver0.30.30.60.80.30.70.50.20.40.6-0.20.5
Mg content in liver0.00.00.10.3-0.00.20.1-0.20.10.30.00.2
Mn content in liver2.72.95.41.51.92.12.21.1-0.3-0.2-2.22.3
Na content in liver0.70.81.31.20.60.81.10.60.81.0-0.40.9
Rb content in liver0.40.40.70.80.60.70.70.80.40.6-0.50.5
Se content in liver3.23.76.02.42.32.42.31.30.60.9-2.11.9
Sr content in liver0.90.71.4-1.2-1.1-0.7-0.50.10.90.41.1-1.0
Zn content in liver0.40.41.10.51.00.90.50.4-0.4-0.4-1.00.3
Bone: minimum diameter1.73.05.2-1.7-1.8-2.0-2.3-1.9-1.0-1.01.8-1.7
Time in familiar zone, hab. session 10.60.62.10.4-0.40.20.40.81.51.40.50.2
Time in novel zone, hab. session 11.01.03.20.11.10.40.3-0.4-1.8-1.6-1.30.6
Total zone transitions, hab. session 10.30.40.90.70.50.50.70.90.40.5-0.50.9
Total locomotion distance, hab. session 10.30.41.40.1-0.4-0.10.00.91.21.10.5-0.1
Locomotion velocity, hab. session 10.50.72.1-0.1-0.8-0.3-0.20.71.51.30.9-0.5
Time in familiar zone, hab. session 20.30.30.7-0.1-0.6-0.6-0.60.40.50.70.8-0.5
Time in novel zone, hab. session 20.80.82.00.51.21.11.0-0.1-0.5-0.8-1.40.8
Total zone transitions, hab. session 20.40.51.2-0.1-0.8-0.6-0.60.00.91.01.1-0.5
Total locomotion distance, hab. session 21.31.73.2-0.1-1.2-1.1-1.10.31.61.81.8-1.4
Locomotion velocity, hab. session 21.62.14.1-0.2-1.5-1.3-1.40.11.71.82.0-1.6
Novel to familiar place preference ratio0.40.51.20.80.50.60.50.81.01.1-0.20.0
Novelty place preference0.50.61.50.90.50.70.50.81.11.2-0.2-0.1
Time in novel zone, NPP test0.70.71.41.10.70.80.71.01.11.2-0.40.1
Total zone transitions, NPP test0.50.81.5-0.7-0.7-1.1-1.2-0.9-0.6-0.50.8-1.0
Total locomotion distance, NPP test1.11.53.1-0.7-1.3-1.4-1.5-0.40.90.81.6-1.8
Locomotion velocity, NPP test1.82.64.9-1.2-1.8-1.9-2.0-0.80.80.72.1-2.2
Intraocular pressure0.30.51.4-0.60.1-0.6-0.6-0.7-1.2-1.1-0.1-0.4
Delta distance traveled before/after self-admin1.51.62.8-1.6-1.0-1.2-1.2-1.7-1.1-1.50.7-1.1
Delta ambulatory time before/after self-admin1.92.34.6-1.7-1.0-1.4-1.5-2.1-1.5-1.70.8-1.5
Parametrial fat weight0.10.31.3-0.5-0.4-0.5-0.6-0.30.30.10.6-1.1
Pavlov. Cond. lever latency1.92.43.81.71.91.91.81.6-0.00.3-1.81.6
Pavlov. Cond. magazine entry latency0.00.10.20.40.10.0-0.3-0.10.20.40.00.1
Pavlov. Cond. change in total contacts0.40.40.9-0.5-1.0-0.7-0.7-0.40.60.50.9-0.6
Pavlov. Cond. index score0.70.91.7-0.6-1.1-1.1-1.3-1.00.30.21.2-1.1
Pavlov. Cond. latency score1.21.52.6-0.9-1.5-1.5-1.6-1.30.20.11.5-1.4
Pavlov. Cond. lever contacts2.02.44.1-1.6-2.0-1.9-1.8-1.50.2-0.11.9-1.6
Pavlov. Cond. magazine entry number0.40.51.30.30.70.81.11.00.20.1-0.70.7
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.5-0.40.10.40.20.50.10.2-0.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.0-0.3-0.9-0.8-1.0-0.70.40.40.9-0.8
Pavlov. Cond. response bias0.40.51.0-0.4-0.9-0.8-1.0-0.80.30.20.9-0.6
Pavlov. Cond. lever latency2.12.94.52.11.71.91.91.81.01.3-1.61.8
Pavlov. Cond. magazine entry latency1.11.45.1-0.30.7-0.2-0.8-1.3-2.2-1.9-0.7-0.1
Pavlov. Cond. change in total contacts0.81.21.9-1.2-0.6-1.1-1.2-1.3-1.3-1.40.5-0.9
Pavlov. Cond. index score1.01.42.8-1.1-0.3-1.0-1.2-1.5-1.7-1.70.3-0.9
Pavlov. Cond. latency score1.01.32.8-1.1-0.3-0.9-1.1-1.5-1.7-1.70.2-0.7
Pavlov. Cond. lever contacts2.12.94.0-2.0-1.5-1.9-2.0-1.9-1.4-1.51.4-1.6
Pavlov. Cond. magazine entry number1.62.06.40.8-0.30.71.11.82.52.40.50.5
Pavlov. Cond. intertrial magazine entries0.71.02.5-0.8-1.4-0.7-0.30.11.61.11.3-1.0
Pavlov. Cond. lever-magazine prob. diff.1.01.33.3-0.9-0.1-0.8-1.1-1.5-1.8-1.80.0-0.7
Pavlov. Cond. response bias1.72.33.3-1.7-0.9-1.5-1.7-1.8-1.6-1.80.8-1.4
Time in closed arm before self-admin2.83.66.2-2.5-2.3-2.3-2.1-1.7-0.8-1.11.9-1.7
Time in closed arm after self-admin0.90.91.7-1.2-1.3-1.1-1.1-0.8-0.2-0.31.1-0.9
Time in open arm before self-admin4.65.010.53.23.12.52.31.50.31.0-2.51.9
Time in open arm after self-admin0.10.10.30.1-0.3-0.4-0.4-0.30.00.30.5-0.1
Bone: periosteal estimation0.30.61.3-0.6-0.7-1.0-1.2-0.7-0.2-0.10.9-1.0
Bone: periosteal perimeter0.30.50.9-0.7-0.7-0.9-1.0-0.7-0.2-0.30.8-1.0
Bone: post-yield work1.52.35.3-0.8-2.2-1.5-1.5-0.61.41.32.3-1.1
Progressive ratio test 1 active lever presses0.30.41.40.0-0.30.40.50.81.20.90.10.1
Progressive ratio test 1 breakpoint0.30.41.30.0-0.30.40.60.81.10.80.10.2
Progressive ratio test 1 inactive lever presses0.30.41.6-0.2-0.80.10.20.71.30.90.5-0.0
Progressive ratio test 2 active lever presses0.70.81.70.70.41.01.11.30.90.8-0.61.1
Progressive ratio test 2 breakpoint0.70.81.60.70.51.01.01.30.80.7-0.61.1
Progressive ratio test 2 inactive lever presses0.50.91.80.80.20.90.81.31.31.3-0.10.6
Incentive Sensitization - Responses0.50.71.40.90.80.90.91.20.50.7-0.71.0
Incentive Sensitization - Breakpoint0.60.71.50.90.70.90.91.20.60.8-0.60.9
Sum of active levers in priming session hrs 5-60.80.81.8-1.3-0.7-0.8-0.8-0.8-1.1-1.40.3-0.1
Progressive ratio0.30.51.70.31.00.10.1-0.3-1.3-1.0-0.90.3
Food seeking constrained by brief footshock1.21.52.81.41.21.41.71.00.60.7-1.21.4
Seeking ratio, punishment vs. effort0.91.34.10.8-0.21.01.11.22.01.80.20.6
Retroperitoneal fat weight0.93.68.60.72.51.00.7-0.7-2.9-2.6-2.61.4
Reaction time number correct0.81.63.4-1.3-0.5-1.1-1.2-1.5-1.9-1.80.4-0.7
Reaction time mean minus median0.10.10.3-0.5-0.6-0.3-0.5-0.30.0-0.00.5-0.1
Reaction time mean minus median AUC0.20.61.7-1.2-1.3-0.7-0.7-0.50.1-0.21.0-0.2
Reaction time num false alarms0.30.51.1-0.9-0.7-0.4-0.30.21.00.50.7-1.0
Reaction time num false alarms AUC0.30.41.0-1.0-0.7-0.5-0.40.10.70.30.7-1.0
Reaction time trials correct on left0.81.63.4-1.3-0.5-1.1-1.2-1.5-1.9-1.80.4-0.7
Reaction time trials on left0.81.53.4-1.3-0.5-1.1-1.1-1.5-1.8-1.80.4-0.7
Reaction time mean0.20.31.30.50.50.50.4-0.0-0.6-0.3-0.61.1
Reaction time mean AUC0.10.21.00.30.30.40.3-0.1-0.5-0.3-0.41.0
Median of all reaction times0.50.82.30.90.81.00.90.4-0.4-0.1-1.01.5
Reaction time omissions0.60.92.40.60.81.21.20.90.10.1-1.11.5
Reaction time false alarm rate0.40.62.6-0.2-0.40.10.20.91.61.20.4-0.6
Reaction time premature initiation rate0.60.93.0-1.1-1.7-0.9-0.5-0.00.80.41.4-0.4
Reaction time premature initiations0.81.33.4-1.5-1.8-1.4-1.0-0.70.0-0.31.5-0.8
Std. dev. reaction times0.10.10.3-0.4-0.3-0.2-0.4-0.4-0.5-0.50.10.3
Reaction time trials completed0.81.53.4-1.3-0.5-1.1-1.1-1.5-1.8-1.80.4-0.7
Reaction time trials AUC0.61.23.1-1.1-0.4-0.9-0.9-1.3-1.8-1.60.2-0.5
Run reversals in cocaine runway, females0.50.51.31.01.10.70.60.2-0.30.0-1.00.4
Run reversals in cocaine runway, males0.40.41.30.5-0.00.30.60.71.11.10.10.3
Latency to leave start box in cocaine runway0.30.30.6-0.4-0.7-0.3-0.40.10.70.70.8-0.5
Latency to leave start box in cocaine runway, F0.30.40.9-0.9-0.5-0.6-0.8-0.5-0.4-0.50.5-0.5
Latency to leave start box in cocaine runway, M1.21.13.50.7-0.30.60.61.11.91.90.60.0
Std. dev. time between licks in bursts0.91.22.11.41.31.21.20.90.20.4-1.21.3
Total sessions with >9 infusions0.10.20.6-0.2-0.30.30.40.60.40.2-0.10.8
Short access day 1 total inactive lever presses2.53.310.5-0.1-1.9-0.3-0.31.03.22.92.2-1.1
Short access day 10 total inactive lever presses0.40.92.1-0.6-1.4-1.0-1.0-0.70.40.41.5-1.0
Short access day 1 total infusions0.40.51.3-0.3-1.1-0.2-0.20.11.11.01.1-0.1
Short access day 10 total infusions0.91.12.60.70.21.11.21.61.41.1-0.40.8
Short access total infusions0.30.40.90.1-0.40.50.60.71.00.80.20.6
Short access day 1 locomotion0.70.82.0-0.7-1.4-0.8-0.50.01.00.71.4-0.8
Short access day 10 total locomotion0.30.62.10.2-0.60.20.30.91.51.30.60.1
Short access total locomotion0.30.41.10.0-0.60.20.30.71.10.90.50.3
One hour access (0.3 mA shock)3.94.47.02.62.12.62.22.41.41.7-1.81.8
Compulsive drug intake0.70.82.60.91.60.70.40.3-0.7-0.4-1.50.6
One hour access (shock baseline)1.21.83.31.50.51.41.31.81.71.8-0.31.0
Social response proportion1.21.33.00.71.50.81.00.2-1.3-1.1-1.71.2
Social responses0.81.02.6-0.9-0.3-0.9-0.8-1.1-1.6-1.60.1-0.2
Social time0.00.00.1-0.1-0.1-0.3-0.3-0.00.00.10.2-0.4
Soleus weight2.67.616.7-1.1-3.3-1.6-1.60.24.13.63.8-2.7
Bone: stiffness0.61.03.21.40.30.50.31.01.51.80.10.5
Tibialis anterior weight4.716.129.6-4.3-5.4-4.4-4.2-2.71.50.65.4-4.4
Time to tail flick, vehicle, before self-admin1.01.02.3-1.5-0.8-1.1-0.9-1.0-1.1-1.30.5-0.5
Time to tail flick, vehicle, after self-admin0.81.12.7-1.6-1.5-1.2-0.9-0.5-0.0-0.41.2-0.6
Time to tail flick, test, before self-admin1.61.75.11.0-0.20.71.01.62.32.10.30.7
Time to tail flick, test, after self-admin0.40.51.1-0.7-1.1-0.5-0.50.00.70.51.0-0.6
Delta time to tail flick, vehicle, before/after SA0.10.10.20.2-0.00.10.40.40.50.3-0.00.2
Delta time to tail flick, test, before/after SA0.50.61.4-0.7-0.2-0.6-0.7-1.0-1.2-1.00.2-0.6
Tibia length0.20.61.8-0.5-0.2-0.5-0.4-1.3-1.2-1.3-0.1-0.1
Ambulatory time before self-admin0.50.71.7-0.1-1.3-0.3-0.40.11.31.21.3-0.2
Ambulatory time after self-admin1.92.34.1-1.7-2.0-1.5-1.6-1.8-0.3-0.71.7-1.3
Bone: tissue strength0.70.71.5-0.6-1.0-0.8-1.1-0.50.40.51.2-0.9
Total heroin consumption0.50.61.5-1.2-0.9-0.9-0.7-0.5-0.3-0.70.6-0.3
Bone: trabecular number2.94.810.1-1.8-1.0-2.2-2.3-2.9-3.2-2.90.7-1.3
Bone: trabecular spacing0.71.03.50.4-0.20.60.61.11.91.70.40.2
Bone: trabecular thickness1.51.93.6-1.1-1.2-1.7-1.9-1.5-1.1-0.81.4-1.3
Bone: trabecular tissue density1.11.66.01.3-0.5-0.0-0.50.32.02.51.2-0.7
Water consumed over 24 hours0.30.31.10.20.80.1-0.1-0.4-1.0-0.9-0.70.1
Number of responses in last shaping day0.30.40.6-0.5-0.7-0.6-0.8-0.6-0.1-0.20.7-0.8