Hub : Genes

Tspan10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Tspan10 0.03 0.02 6.9e-04 0.03 0.03 0.02 0.03 3.5e-04 3.8e-04 8.6e-04 3.5e-04
2 pVTA gene expression Tspan10 0.45 0.13 0.0e+00 0.52 0.52 0.52 0.53 9.5e-26 8.2e-26 3.5e-26 1.0e-26
3 RMTg gene expression Tspan10 0.29 0.12 4.7e-07 0.21 0.13 0.18 -0 2.6e-06 2.4e-04 1.7e-05 3.5e-01
4 Eye mRNA stability Tspan10 0.46 0.22 9.3e-04 0.3 0.24 0.28 0.28 1.7e-05 1.6e-04 3.0e-05 3.4e-05
5 LHb gene expression Tspan10 0.18 0.12 6.1e-03 0.02 -0 0.03 0.01 1.1e-01 4.3e-01 6.4e-02 1.4e-01
6 Brain gene expression Tspan10 0.06 0.04 8.9e-04 0.03 0.01 0.03 0.02 4.7e-04 2.7e-02 3.6e-04 6.1e-03
7 Eye gene expression Tspan10 0.33 0.17 2.6e-03 0.05 0.14 0.01 0.08 6.5e-02 3.8e-03 2.2e-01 2.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.30.51.3-0.60.7-0.60.1-1.1-0.80.6
Area under the delay curve1.51.62.51.6-1.61.61.40.91.10.1
BMI with tail0.82.73.9-1.91.7-1.80.5-2.0-1.71.4
BMI without tail6.713.819.8-4.14.0-4.00.9-4.4-4.33.1
Body weight3.414.223.6-4.94.6-4.7-2.7-3.4-3.80.4
Weight adjusted by age1.71.93.8-1.91.8-1.8-0.8-1.2-1.0-0.1
Bone surface0.30.51.0-0.80.8-0.8-1.0-0.5-0.6-0.3
Bone volume0.30.50.7-0.80.8-0.8-0.5-0.8-0.70.1
Breakpoint value in progressive ratio session0.20.20.4-0.50.4-0.40.00.40.5-0.7
Number of licking bursts0.40.51.4-0.60.6-0.6-0.5-0.8-1.20.5
Context. condit. distance diff. score2.12.64.7-1.01.0-1.01.1-2.1-2.12.2
Locomotion velocity, session 13.23.55.82.0-2.02.00.12.02.4-1.5
Locomotion distance, session 11.82.23.81.9-1.91.91.90.00.51.2
Locomotion velocity, session 23.64.27.12.7-2.72.70.42.11.8-0.6
Locomotion distance, session 20.50.61.30.7-0.70.71.1-0.6-0.41.2
Locomotion velocity, session 31.72.02.91.7-1.71.70.21.41.7-0.8
Locomotion distance, session 32.22.43.92.0-2.02.01.31.21.5-0.0
Stereotopy head waving bouts, day 31.01.12.91.0-1.01.0-0.41.71.1-0.8
Stereotopy head waving duration, day 30.40.51.20.8-0.80.8-0.31.10.5-0.4
Locomotion velocity, session 70.40.50.70.8-0.80.80.80.30.40.4
Locomotion distance, session 72.22.86.11.8-1.81.82.5-0.50.11.8
Stereotopy head waving bouts, day 70.20.20.4-0.60.6-0.6-0.00.0-0.50.2
Stereotopy head waving duration, day 70.50.61.1-0.90.9-0.9-1.10.2-0.7-0.3
Locomotion velocity, session 80.70.82.30.6-0.60.61.3-0.6-0.71.5
Locomotion distance, session 82.94.310.2-0.70.7-0.72.1-2.8-2.53.2
Degree of sensitization distance1.11.12.2-0.80.8-0.80.2-1.5-1.41.2
Degree of sensitization stereotypy0.50.61.0-1.01.0-1.00.0-0.5-0.80.5
Conditioned locomotion4.35.06.8-2.62.6-2.6-0.7-2.5-2.61.2
Cocaine response after cond. corrected0.30.41.30.4-0.40.40.40.71.2-0.5
Cocaine response after cond. not corrected0.70.81.70.9-0.90.90.51.01.3-0.4
Cocaine response before conditioning0.30.40.91.0-0.91.00.20.3-0.10.4
Saline control response2.43.15.1-2.22.3-2.2-1.4-1.3-1.70.0
Bone: connectivity density0.20.41.2-0.10.1-0.10.1-0.8-1.10.8
Bone: cortical apparent density2.22.94.62.1-2.12.11.31.21.9-0.2
Bone: cortical area4.56.811.8-3.43.4-3.4-2.6-1.4-1.8-0.8
Bone: cortical porosity2.12.36.0-0.60.6-0.6-1.91.71.6-2.4
Bone: cortical porosity1.61.73.9-0.90.9-0.9-1.71.31.1-2.0
Bone: cortical thickness3.45.69.3-3.13.1-3.1-2.8-0.6-0.9-1.6
Bone: cortical thickness1.01.22.3-1.51.5-1.5-1.0-0.3-0.3-0.5
Bone: cortical tissue density2.53.35.32.3-2.32.31.41.32.0-0.2
Condit. Reinf. active minus inactive responses1.82.03.5-1.91.9-1.9-0.3-1.2-1.40.4
Condit. Reinf. active-inactive response ratio0.80.91.6-1.31.3-1.30.1-1.0-0.70.3
Condit. Reinf. active responses3.34.06.8-2.62.6-2.6-0.8-1.6-2.10.5
Condit. Reinf. inactive responses0.80.91.5-1.21.2-1.2-0.6-0.6-1.10.3
Incentive salience index mean1.62.03.2-1.81.8-1.8-0.5-1.2-1.50.4
Condit. Reinf. lever presses0.20.30.9-0.30.3-0.30.2-0.7-0.90.7
Condit. Reinf. active minus inactive responses0.60.81.2-1.01.0-1.0-0.8-0.8-1.10.2
Condit. Reinf. active-inactive response ratio1.51.63.8-1.41.4-1.4-2.0-0.3-0.9-0.7
Condit. Reinf. active responses0.20.30.7-0.40.4-0.40.3-0.8-0.70.7
Condit. Reinf. inactive responses0.70.83.30.7-0.70.71.8-0.30.40.9
Condit. Reinf. lever presses0.60.81.6-0.50.5-0.51.2-1.3-0.71.3
Condit. Reinf. lever reinforcers received0.50.71.3-0.50.5-0.51.0-1.1-0.71.2
Conditioned reinforcement - actives0.30.31.1-0.30.3-0.2-0.5-0.5-1.10.7
Conditioned reinforcement - inactives0.70.81.6-1.01.0-0.9-1.3-0.6-0.7-0.3
Conditioned locomotion0.30.41.5-0.50.4-0.4-1.2-0.5-0.70.1
Patch foraging indifference point 0 sec0.10.10.2-0.40.5-0.50.4-0.4-0.00.1
Patch foraging indifference point AUC0.00.00.20.1-0.20.20.4-0.2-0.10.2
Delay disc. indifference point, 0s delay0.10.10.70.2-0.20.20.90.1-0.00.1
Delay disc. indifference point, 16s delay1.81.84.81.3-1.31.32.2-0.60.31.5
Delay disc. indifference point, 2s delay0.50.50.70.8-0.90.80.70.70.7-0.3
Delay disc. indifference point, 24s delay4.74.67.12.6-2.72.60.82.12.3-0.6
Delay disc. indifference point, 4s delay0.50.50.80.8-0.80.80.50.90.8-0.4
Delay disc. indifference point, 8s delay1.11.21.61.2-1.21.20.31.31.2-0.7
Indifference point function ln k0.40.61.01.0-0.90.90.90.20.70.4
Indifference point function log k0.40.61.01.0-0.90.90.90.20.70.4
Patch foraging total patch changes 0 sec0.10.20.6-0.40.5-0.50.7-0.6-0.00.4
Patch foraging total patch changes 12 sec0.00.10.2-0.0-0.10.10.10.20.5-0.4
Patch foraging total patch changes 18 sec0.81.04.00.1-0.00.02.0-1.3-0.11.2
Patch foraging total patch changes 24 sec0.60.71.7-1.01.0-1.00.3-1.3-0.40.4
Patch foraging total patch changes 6 sec0.20.30.5-0.70.7-0.6-0.60.3-0.1-0.6
Patch foraging time to switch 0 sec0.30.50.80.8-0.90.80.00.80.7-0.3
Patch foraging water rate 0 sec1.82.94.3-2.12.0-2.00.1-1.9-1.71.1
Patch foraging water rate 12 sec0.81.22.5-0.70.7-0.71.1-1.5-1.11.6
Patch foraging water rate 18 sec1.31.83.5-1.11.1-1.10.4-1.9-1.81.5
Patch foraging water rate 24 sec3.34.78.2-2.02.0-2.01.3-2.9-2.22.4
Patch foraging water rate 6 sec0.40.61.4-0.40.4-0.40.4-1.2-1.00.9
Seeking ratio, delayed vs. immediate footshock1.41.62.7-1.61.5-1.7-0.7-1.0-1.60.1
Distance traveled before self-admin0.60.71.1-1.01.1-1.0-0.90.0-0.2-0.8
Distance traveled after self-admin0.80.92.0-0.70.9-0.90.8-1.4-0.80.9
Extensor digitorum longus weight0.62.55.5-0.70.7-0.71.4-2.3-1.82.4
Bone: elastic displacement0.91.01.9-1.41.4-1.4-1.0-0.3-0.2-0.7
Bone: elastic work4.45.79.5-3.13.1-3.1-2.6-0.1-0.2-2.1
Bone: endosteal estimation0.40.82.0-0.20.2-0.20.8-1.4-1.11.4
Bone: endosteal perimeter0.61.21.9-1.41.4-1.4-1.2-0.8-0.9-0.2
Epididymis fat weight1.43.44.9-2.22.1-2.1-0.2-2.2-2.11.1
Delta time in closed arm before/after self-admin0.50.53.00.0-0.20.1-1.7-0.3-0.7-0.1
Delta time in open arm before/after self-admin0.50.52.2-0.10.2-0.11.5-0.5-0.20.9
Diff in mean of infusions in LGA sessions0.20.20.40.6-0.60.60.30.40.4-0.2
Delay discount exponential model param2.22.43.6-1.91.9-1.9-1.3-1.3-1.60.2
Extinction: sum of active levers before priming1.21.21.91.4-1.31.30.61.01.2-0.4
Active lever presses in extinction session 60.70.61.80.5-0.70.70.00.91.3-0.8
Bone: final force3.96.311.3-3.43.4-3.4-1.9-1.6-1.9-0.3
Bone: final moment4.36.912.9-3.63.6-3.6-2.1-1.5-1.8-0.6
Food consumed during 24 hour testing period0.30.40.7-0.80.8-0.8-0.1-0.5-0.60.3
Glucose5.78.518.02.6-2.62.6-0.03.74.2-2.6
Heart weight0.30.40.9-1.00.9-0.90.3-0.4-0.20.1
Delay discount hyperbolic model param2.22.33.5-1.81.9-1.8-1.4-1.3-1.50.1
Intermittent access intake day 1-15 change0.30.30.5-0.70.6-0.7-0.5-0.2-0.4-0.3
Intermittent access intake escalation0.30.30.6-0.70.6-0.7-0.5-0.2-0.6-0.0
Intermittent access intake escalation 21.21.12.6-1.21.0-1.1-1.60.3-0.6-1.0
Intermitt. access day 1 inactive lever presses0.40.40.6-0.80.8-0.8-0.7-0.6-0.3-0.4
Intermitt. access day 15 inactive lever presses1.11.32.3-1.11.1-1.1-0.6-1.5-1.30.7
Intermitt. access escalation Index1.51.42.5-1.11.1-1.1-0.2-1.4-1.61.1
Intermittent access day 1 total infusions0.40.40.9-0.80.9-0.8-0.2-0.6-0.70.2
Intermittent access day 15 total infusions0.60.71.0-1.01.0-0.9-0.5-0.7-1.00.3
Intermittent access terminal intake (last 3 days)1.01.11.7-1.31.3-1.2-1.1-0.6-1.1-0.1
Intermittent access total infusions0.60.61.0-0.91.0-0.9-0.5-0.6-1.00.2
Intermittent access day 1 locomotion0.50.50.7-0.80.8-0.7-0.4-0.9-0.80.5
Intermittent access day 15 total locomotion0.50.51.7-0.80.7-0.6-1.30.0-0.4-0.5
Intermittent access total locomotion0.50.61.4-0.80.8-0.7-1.2-0.5-0.6-0.0
Intermittent access standard deviation1.01.12.70.7-0.70.7-0.21.61.2-1.3
Left kidney weight0.30.83.0-0.40.2-0.2-1.70.80.0-1.2
Right kidney weight0.10.42.1-0.0-0.10.1-1.50.5-0.3-0.7
Cocaine induced anxiety1.92.13.8-1.72.0-1.8-1.6-0.20.2-1.6
Post-drug Anxiety0.30.30.9-0.20.4-0.3-0.40.11.0-0.9
Baseline Anxiety4.04.38.22.8-2.92.81.51.11.40.7
Tail length4.814.621.8-4.74.6-4.6-2.0-3.7-4.41.3
Length with tail2.17.712.4-3.43.3-3.2-3.5-1.6-2.2-1.1
Length without tail1.73.68.60.7-0.70.7-2.82.21.7-2.9
Times rat made contact with spout1.01.22.4-1.01.0-1.0-1.50.70.5-1.5
Lifetime Intake0.20.20.4-0.60.5-0.5-0.6-0.3-0.70.1
Liver weight, left0.50.81.80.4-0.40.4-0.81.21.2-1.4
Liver weight, right2.23.69.0-2.12.0-2.0-3.0-0.9-1.7-0.8
Locomotor activity0.50.81.61.2-1.21.20.60.40.9-0.1
Locomotor testing distance0.60.91.61.1-1.21.21.1-0.00.70.7
Locomotor testing rearing0.30.51.10.6-0.70.71.0-0.30.20.9
Locomotion in novel chamber0.30.30.80.3-0.30.30.9-0.7-0.20.8
Locomotion in novel chamber post-restriction1.62.03.4-1.81.8-1.8-1.3-0.5-1.5-0.3
Fecal boli incidents, locomotor time 10.30.30.60.7-0.80.70.70.10.30.3
Change in fecal boli incidents, locomotor task3.02.84.61.8-1.61.70.32.12.1-1.5
Time >=10cm from walls, locomotor time 11.21.32.4-1.01.1-1.10.1-1.3-1.61.1
Bouts of movement, locomotor time 11.41.52.11.5-1.51.41.11.11.3-0.1
Total resting periods, locomotor time 11.82.02.91.7-1.71.70.71.51.6-0.5
Rest time, locomotor task time 10.60.61.10.6-0.70.7-0.70.81.0-0.9
Distance moved, locomotor task time 10.80.91.5-1.01.1-1.10.0-1.2-1.00.6
Vertical activity count, locomotor time 12.12.23.6-1.51.5-1.50.3-1.9-1.81.3
Time >=10cm from walls, locomotor time 20.20.20.7-0.10.2-0.2-0.80.4-0.6-0.2
Bouts of movement, locomotor time 20.91.01.61.2-1.21.21.30.60.60.4
Total resting periods, locomotor time 20.60.61.20.9-0.90.91.10.30.20.7
Rest time, locomotor task time 20.10.10.10.2-0.30.3-0.30.20.0-0.3
Distance moved, locomotor task time 20.00.10.3-0.10.2-0.2-0.1-0.5-0.10.2
Vertical activity count, locomotor time 20.60.71.6-0.50.5-0.40.4-1.3-1.01.1
Light reinforcement 11.93.46.1-2.01.9-1.90.3-1.9-2.51.7
Light reinforcement 22.63.45.4-2.32.2-2.2-1.1-1.4-2.30.7
Bone: marrow area0.40.82.0-0.20.2-0.20.8-1.4-1.01.4
Bone: maximum diameter1.42.64.0-1.91.9-1.9-2.0-0.8-1.4-0.4
Bone: maximum force4.06.912.3-3.53.5-3.5-1.8-1.9-2.2-0.1
Bone: maximum moment4.47.513.7-3.73.7-3.7-2.0-1.8-2.1-0.3
Mean time between licks in bursts1.01.32.31.5-1.51.51.10.60.80.3
Mean num. licks in bursts0.40.41.3-0.10.1-0.1-0.20.81.1-1.0
Cd content in liver1.51.73.01.5-1.51.51.70.40.90.8
Co content in liver0.10.10.50.3-0.30.30.7-0.00.20.4
Cu content in liver0.81.02.9-0.30.3-0.3-1.31.10.9-1.7
Fe content in liver0.60.81.31.1-1.11.11.1-0.10.60.4
K content in liver2.42.44.7-1.61.7-1.7-1.0-1.3-2.20.7
Mg content in liver1.41.44.2-0.50.6-0.60.1-1.5-2.11.6
Mn content in liver0.30.31.0-0.50.6-0.6-1.00.2-0.5-0.4
Na content in liver0.10.10.6-0.10.1-0.1-0.80.1-0.2-0.3
Rb content in liver1.21.53.0-1.11.2-1.2-0.0-1.5-1.71.1
Se content in liver0.30.40.5-0.70.7-0.7-0.3-0.6-0.70.3
Sr content in liver1.71.53.50.4-0.50.5-0.71.91.7-1.7
Zn content in liver0.50.51.80.2-0.20.2-1.31.00.1-0.9
Bone: minimum diameter2.44.47.9-2.82.8-2.8-1.9-1.0-1.5-0.6
Time in familiar zone, hab. session 10.20.20.70.3-0.30.30.30.30.8-0.3
Time in novel zone, hab. session 10.10.10.3-0.10.1-0.10.1-0.1-0.60.3
Total zone transitions, hab. session 10.40.61.90.6-0.60.61.4-0.00.10.9
Total locomotion distance, hab. session 10.60.81.8-0.40.5-0.41.3-0.9-0.81.3
Locomotion velocity, hab. session 10.60.91.7-0.50.5-0.51.2-1.2-0.91.3
Time in familiar zone, hab. session 20.40.41.50.5-0.50.51.2-0.60.30.7
Time in novel zone, hab. session 20.10.10.40.2-0.20.2-0.50.6-0.1-0.2
Total zone transitions, hab. session 21.21.54.20.3-0.30.31.7-1.4-1.22.0
Total locomotion distance, hab. session 21.92.54.9-0.90.9-0.91.2-2.0-2.22.2
Locomotion velocity, hab. session 22.02.75.3-1.21.2-1.20.9-2.1-2.32.1
Novel to familiar place preference ratio1.51.52.7-1.61.6-1.6-1.20.30.0-1.1
Novelty place preference1.51.52.4-1.61.6-1.6-1.20.40.1-1.2
Time in novel zone, NPP test1.11.22.1-1.41.4-1.4-1.00.3-0.0-0.9
Total zone transitions, NPP test1.52.15.80.4-0.40.41.9-1.7-1.42.4
Total locomotion distance, NPP test2.23.07.4-0.50.6-0.51.8-2.2-2.22.7
Locomotion velocity, NPP test1.72.45.3-0.70.7-0.71.5-2.0-2.02.3
Intraocular pressure0.50.71.0-1.01.0-1.00.3-0.8-0.80.6
Delta distance traveled before/after self-admin0.80.92.80.4-0.30.31.7-1.0-0.21.4
Delta ambulatory time before/after self-admin1.01.12.61.1-1.01.01.6-0.50.31.3
Parametrial fat weight1.42.84.7-2.22.0-2.0-1.5-1.6-1.3-0.1
Pavlov. Cond. lever latency1.92.48.00.8-0.80.82.8-1.1-0.42.3
Pavlov. Cond. magazine entry latency1.62.13.8-1.61.6-1.6-2.00.30.3-1.8
Pavlov. Cond. change in total contacts0.90.92.6-0.30.3-0.3-1.01.11.2-1.6
Pavlov. Cond. index score2.43.16.9-2.02.0-2.0-2.6-0.1-0.5-1.7
Pavlov. Cond. latency score2.32.98.3-1.61.6-1.6-2.90.4-0.2-2.0
Pavlov. Cond. lever contacts1.01.24.1-0.90.8-0.9-2.00.4-0.1-1.4
Pavlov. Cond. magazine entry number1.82.35.21.3-1.31.32.1-0.9-0.92.3
Pavlov. Cond. intertrial magazine entries0.81.02.0-0.70.7-0.70.7-1.4-1.21.3
Pavlov. Cond. lever-magazine prob. diff.2.43.06.0-2.02.0-2.0-2.5-0.2-0.4-1.6
Pavlov. Cond. response bias1.82.25.0-1.31.3-1.3-2.20.60.5-2.1
Pavlov. Cond. lever latency1.31.83.51.0-1.01.0-1.21.91.3-1.7
Pavlov. Cond. magazine entry latency1.72.06.41.2-1.21.22.5-0.50.21.7
Pavlov. Cond. change in total contacts1.01.34.80.2-0.20.22.2-1.2-0.31.7
Pavlov. Cond. index score1.01.35.00.1-0.10.12.2-1.2-0.21.7
Pavlov. Cond. latency score1.11.34.40.0-0.00.02.1-1.3-0.51.8
Pavlov. Cond. lever contacts1.82.44.8-1.31.3-1.31.2-2.2-1.61.8
Pavlov. Cond. magazine entry number1.62.07.2-0.90.9-0.9-2.70.8-0.1-1.8
Pavlov. Cond. intertrial magazine entries1.21.62.4-1.51.5-1.5-1.2-1.0-1.30.1
Pavlov. Cond. lever-magazine prob. diff.1.21.55.90.3-0.30.32.4-1.1-0.11.7
Pavlov. Cond. response bias1.01.43.1-0.40.4-0.41.7-1.6-0.91.7
Time in closed arm before self-admin0.60.72.10.3-0.30.30.61.51.1-0.9
Time in closed arm after self-admin2.12.14.10.9-1.11.1-1.22.01.6-1.9
Time in open arm before self-admin0.40.41.80.2-0.40.3-1.3-0.5-0.70.1
Time in open arm after self-admin0.30.40.90.2-0.10.20.9-0.8-0.41.0
Bone: periosteal estimation1.73.55.6-2.42.4-2.4-1.3-1.7-1.80.3
Bone: periosteal perimeter2.54.18.6-2.42.4-2.4-2.9-0.2-0.7-1.7
Bone: post-yield work0.30.41.0-0.00.0-0.00.7-0.7-0.71.0
Progressive ratio test 1 active lever presses1.21.31.9-1.41.4-1.3-0.7-1.1-1.30.3
Progressive ratio test 1 breakpoint1.51.62.6-1.61.6-1.6-0.7-1.2-1.40.3
Progressive ratio test 1 inactive lever presses2.32.53.8-2.01.9-1.9-0.6-1.8-1.70.7
Progressive ratio test 2 active lever presses0.50.51.5-0.80.7-0.6-1.2-0.3-0.6-0.2
Progressive ratio test 2 breakpoint0.60.71.1-1.00.9-0.8-1.1-0.5-0.90.1
Progressive ratio test 2 inactive lever presses0.30.31.0-0.60.5-0.5-1.0-0.1-0.4-0.4
Incentive Sensitization - Responses0.20.20.5-0.40.4-0.3-0.7-0.2-0.1-0.2
Incentive Sensitization - Breakpoint0.10.10.6-0.30.3-0.2-0.8-0.10.0-0.3
Sum of active levers in priming session hrs 5-60.50.51.5-0.80.6-0.71.20.20.6-0.2
Progressive ratio0.30.40.80.8-0.90.80.40.40.5-0.1
Food seeking constrained by brief footshock0.30.40.60.4-0.60.60.30.70.8-0.7
Seeking ratio, punishment vs. effort0.10.10.3-0.50.5-0.40.2-0.4-0.30.2
Retroperitoneal fat weight4.013.021.5-4.64.6-4.6-1.7-3.7-3.30.7
Reaction time number correct4.05.713.9-0.80.8-0.82.8-3.2-2.53.7
Reaction time mean minus median0.40.61.20.4-0.40.3-1.00.90.7-1.1
Reaction time mean minus median AUC0.20.31.5-0.10.0-0.1-1.20.2-0.1-0.6
Reaction time num false alarms0.40.61.30.6-0.60.61.11.00.70.1
Reaction time num false alarms AUC0.60.91.41.0-1.01.01.20.90.80.3
Reaction time trials correct on left4.05.713.9-0.80.8-0.82.8-3.2-2.53.7
Reaction time trials on left4.15.914.3-0.80.8-0.82.8-3.3-2.53.8
Reaction time mean0.30.50.7-0.80.7-0.8-0.1-0.8-0.70.4
Reaction time mean AUC0.60.71.3-0.90.8-0.90.0-1.1-1.10.9
Median of all reaction times0.50.71.2-0.90.8-0.90.2-1.1-0.90.8
Reaction time omissions0.30.30.9-0.40.4-0.40.0-0.9-0.80.7
Reaction time false alarm rate1.82.46.31.3-1.31.2-0.32.51.9-1.6
Reaction time premature initiation rate1.52.02.81.6-1.61.71.61.11.5-0.0
Reaction time premature initiations1.62.38.41.0-1.01.12.9-0.70.02.0
Std. dev. reaction times0.10.20.30.5-0.60.50.30.00.30.2
Reaction time trials completed4.15.914.3-0.80.8-0.82.8-3.3-2.53.8
Reaction time trials AUC4.15.914.2-0.80.8-0.82.8-3.3-2.53.8
Run reversals in cocaine runway, females1.21.15.30.6-0.40.42.3-0.30.21.4
Run reversals in cocaine runway, males1.31.23.5-0.90.9-1.0-1.90.5-0.2-1.4
Latency to leave start box in cocaine runway0.20.30.70.6-0.40.50.9-0.10.10.4
Latency to leave start box in cocaine runway, F0.40.51.20.4-0.30.30.9-0.5-0.71.1
Latency to leave start box in cocaine runway, M0.10.10.20.10.10.1-0.20.40.3-0.5
Std. dev. time between licks in bursts3.33.97.7-1.21.2-1.21.6-2.8-2.42.6
Total sessions with >9 infusions0.20.20.40.5-0.50.5-0.70.2-0.20.0
Short access day 1 total inactive lever presses0.30.40.9-0.20.1-0.1-0.4-0.9-1.00.9
Short access day 10 total inactive lever presses1.82.03.3-1.81.8-1.8-1.5-0.9-1.0-0.3
Short access day 1 total infusions0.91.01.91.3-1.41.30.20.80.7-0.1
Short access day 10 total infusions0.40.40.8-0.80.9-0.7-0.7-0.0-0.6-0.3
Short access total infusions0.00.00.1-0.10.0-0.0-0.30.1-0.3-0.1
Short access day 1 locomotion0.60.71.30.8-0.80.8-0.71.10.5-0.8
Short access day 10 total locomotion0.60.71.40.5-0.50.6-1.10.90.8-1.2
Short access total locomotion0.80.91.30.9-0.90.9-1.11.10.5-1.0
One hour access (0.3 mA shock)1.31.52.5-1.61.5-1.4-0.7-1.0-1.40.5
Compulsive drug intake0.60.60.9-0.90.8-0.80.7-1.0-0.60.6
One hour access (shock baseline)0.40.51.6-0.60.6-0.5-1.2-0.2-1.00.3
Social response proportion0.30.30.50.4-0.60.60.7-0.20.40.7
Social responses0.10.10.40.2-0.10.10.2-0.6-0.30.5
Social time0.10.10.30.1-0.20.10.4-0.2-0.10.6
Soleus weight1.23.45.4-2.32.3-2.3-1.5-1.3-2.00.2
Bone: stiffness0.71.11.6-1.31.3-1.3-0.6-1.0-1.10.3
Tibialis anterior weight0.20.51.4-0.40.3-0.3-0.0-1.0-1.20.9
Time to tail flick, vehicle, before self-admin0.10.20.5-0.30.4-0.4-0.2-0.0-0.70.2
Time to tail flick, vehicle, after self-admin1.21.32.41.5-1.51.50.51.10.8-0.1
Time to tail flick, test, before self-admin0.20.20.40.1-0.10.1-0.50.60.4-0.6
Time to tail flick, test, after self-admin0.30.30.80.6-0.60.6-0.90.30.3-0.3
Delta time to tail flick, vehicle, before/after SA0.20.20.40.4-0.50.50.6-0.40.10.6
Delta time to tail flick, test, before/after SA0.40.30.50.7-0.70.7-0.10.50.7-0.4
Tibia length5.916.827.7-5.25.3-5.3-4.9-0.8-1.9-2.6
Ambulatory time before self-admin1.31.42.6-1.61.6-1.6-1.0-0.1-0.7-0.7
Ambulatory time after self-admin0.40.40.7-0.50.8-0.70.4-0.9-0.60.6
Bone: tissue strength1.71.62.6-1.51.5-1.5-0.1-1.3-1.60.8
Total heroin consumption0.30.30.80.1-0.20.2-0.10.80.9-0.9
Bone: trabecular number0.00.10.3-0.00.0-0.0-0.3-0.5-0.30.0
Bone: trabecular spacing2.22.96.6-0.80.8-0.81.9-2.1-1.92.6
Bone: trabecular thickness1.21.43.7-0.40.4-0.4-1.61.31.2-1.9
Bone: trabecular tissue density0.60.91.51.2-1.21.20.70.80.70.0
Water consumed over 24 hours0.60.71.50.2-0.20.2-1.11.20.8-1.2
Number of responses in last shaping day1.11.21.7-1.21.0-1.2-1.1-1.3-1.10.2