Trim15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Trim15 0.07 0.04 8.5e-06 0.04 0.06 0.04 0.06 5.6e-05 3.4e-06 1.0e-04 5.3e-06
2 Brain mRNA stability Trim15 0.06 0.04 3.3e-05 0.01 0.04 0.04 0.04 1.3e-02 1.5e-04 1.5e-04 2.3e-04
3 PL mRNA stability Trim15 0.03 0.02 6.4e-04 0 0.03 0.02 0.01 1.1e-01 8.1e-04 1.1e-03 7.7e-03
4 Brain alternative polyA XM_008772685.4 0.06 0.04 1.6e-05 0.03 0.05 0.04 0.04 6.8e-04 2.9e-05 2.1e-04 1.0e-04
5 Brain alternative polyA NM_001291382.2 0.08 0.04 5.1e-06 0.03 0.05 0.04 0.04 4.0e-04 2.9e-05 1.5e-04 9.9e-05
6 pVTA alternative polyA NM_001291382.2 0.17 0.09 1.4e-11 0.12 0.12 0.15 0.14 5.5e-10 1.1e-09 2.4e-12 1.2e-11
7 PL gene expression Trim15 0.08 0.05 4.6e-09 0.04 0.07 0.07 0.07 1.0e-04 2.2e-08 1.4e-08 3.3e-08
8 pVTA alternative polyA XM_008772685.4 0.16 0.09 2.4e-11 0.12 0.12 0.15 0.14 6.9e-10 6.8e-10 8.7e-12 1.9e-11
9 BLA gene expression Trim15 0.06 0.04 5.8e-03 0.03 0.02 0.02 0.02 8.1e-03 2.4e-02 3.8e-02 4.1e-02
10 Adipose alternative TSS NM_001291382.2 0.05 0.03 5.7e-07 0.06 0.06 0.06 0.06 1.9e-07 4.3e-07 1.0e-06 3.5e-07
11 Adipose alternative TSS XM_008772685.4 0.05 0.03 7.8e-07 0.06 0.06 0.05 0.06 2.7e-07 5.8e-07 1.4e-06 4.6e-07
12 NAcc alternative polyA NM_001291382.2 0.09 0.05 4.1e-15 0.1 0.1 0.1 0.1 3.2e-15 1.5e-15 1.9e-15 1.5e-15
13 PL alternative polyA NM_001291382.2 0.06 0.04 1.4e-07 0.06 0.06 0.05 0.06 2.1e-07 2.6e-07 1.5e-06 5.5e-07
14 PL alternative polyA XM_008772685.4 0.06 0.04 6.9e-08 0.06 0.06 0.06 0.06 1.6e-07 2.0e-07 1.0e-06 4.6e-07
15 NAcc alternative polyA XM_008772685.4 0.1 0.05 2.0e-15 0.1 0.11 0.11 0.11 1.4e-15 4.9e-16 7.3e-16 5.1e-16
16 pVTA intron excision ratio chr20_1711734_1712151 0.06 0.05 9.5e-03 0.02 0.02 0.01 0.01 1.6e-02 1.1e-02 1.9e-02 2.6e-02
17 Eye gene expression Trim15 0.4 0.19 5.0e-03 0.15 0.11 0.16 0.09 2.6e-03 1.1e-02 2.3e-03 1.6e-02
18 pVTA intron excision ratio chr20_1710062_1711619 0.08 0.05 5.6e-03 0.03 0.03 0.03 0.03 3.2e-03 3.9e-03 1.6e-03 3.7e-03
19 OFC alternative polyA NM_001291382.2 0.14 0.09 5.6e-03 0.1 0.05 0.05 0.08 2.2e-03 2.6e-02 2.7e-02 7.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.32.44.4-1.71.6-1.7-2.12.1-1.52.01.60.71.5-1.51.7-1.41.4-1.80.7-0.81.2-1.5
Area under the delay curve1.21.93.30.9-1.21.31.0-1.01.6-1.3-1.6-1.7-1.71.7-1.71.8-1.81.7-0.11.1-0.20.7
BMI with tail0.93.211.2-0.8-0.2-0.10.1-0.20.6-0.8-0.81.5-1.71.7-1.72.1-2.11.7-2.93.3-2.92.8
BMI without tail1.05.211.30.5-1.31.31.3-1.32.0-2.0-2.1-0.2-3.13.1-2.83.0-3.02.8-1.93.4-2.02.6
Body weight4.620.329.63.8-4.84.74.6-4.65.2-5.3-5.3-2.5-5.35.3-5.35.4-5.45.3-0.53.5-1.32.8
Weight adjusted by age1.13.15.92.0-1.72.21.9-1.82.2-2.3-2.1-2.4-1.71.7-1.81.6-1.61.81.30.01.2-0.5
Bone surface0.61.14.31.1-1.01.00.6-0.51.0-0.6-0.9-1.7-0.40.4-0.30.5-0.50.22.1-1.02.1-1.4
Bone volume0.20.53.10.2-0.10.3-0.20.30.40.1-0.3-1.1-0.20.2-0.00.3-0.3-0.01.5-0.61.8-1.3
Breakpoint value in progressive ratio session0.71.24.6-0.90.8-1.1-0.50.4-0.90.50.82.10.5-0.50.8-1.21.2-0.7-1.80.3-2.01.1
Number of licking bursts0.10.31.01.0-0.80.70.9-0.90.4-0.5-0.4-0.70.2-0.2-0.20.3-0.30.20.3-0.90.10.1
Context. condit. distance diff. score2.93.58.20.50.6-0.5-0.30.3-1.51.11.6-0.02.7-2.72.3-2.32.3-2.32.2-2.92.0-2.5
Locomotion velocity, session 10.20.20.80.7-0.50.30.3-0.30.2-0.0-0.2-0.40.2-0.20.3-0.40.4-0.30.9-0.80.7-0.6
Locomotion distance, session 11.11.32.2-1.51.4-1.5-1.51.5-1.31.51.31.31.0-1.01.1-1.11.1-1.1-0.50.2-0.4-0.3
Locomotion velocity, session 20.30.42.00.5-0.60.20.6-0.70.2-0.4-0.20.7-0.20.2-0.3-0.00.00.3-0.90.4-1.41.1
Locomotion distance, session 20.60.81.3-0.80.8-1.0-1.01.0-0.91.10.90.81.0-1.01.1-1.11.1-1.10.3-0.60.5-0.9
Locomotion velocity, session 30.60.73.1-0.80.6-0.7-0.40.4-0.60.40.51.30.1-0.1-0.10.2-0.20.1-1.71.1-1.81.3
Locomotion distance, session 31.31.52.4-1.11.2-1.3-1.21.2-1.51.41.51.01.5-1.51.4-1.41.4-1.4-0.1-0.60.0-0.5
Stereotopy head waving bouts, day 31.31.63.21.7-1.81.61.8-1.81.4-1.6-1.4-0.8-1.01.0-1.11.3-1.31.20.20.1-0.50.6
Stereotopy head waving duration, day 31.11.32.11.4-1.41.41.5-1.51.3-1.4-1.3-0.7-1.11.1-1.21.3-1.31.20.10.4-0.40.6
Locomotion velocity, session 73.03.36.1-0.81.5-1.3-1.51.6-2.01.92.00.02.5-2.52.0-2.12.1-2.11.6-1.61.9-2.0
Locomotion distance, session 72.83.65.7-1.52.1-1.8-2.02.0-2.32.12.30.72.4-2.42.1-2.02.0-2.10.9-1.01.5-1.8
Stereotopy head waving bouts, day 71.92.23.31.5-1.61.71.5-1.41.7-1.5-1.7-1.6-1.61.6-1.71.8-1.81.70.40.6-0.10.7
Stereotopy head waving duration, day 72.12.53.61.6-1.71.81.6-1.61.9-1.7-1.9-1.6-1.81.8-1.81.9-1.91.80.30.7-0.20.9
Locomotion velocity, session 81.92.36.62.6-2.12.02.1-2.01.4-1.5-1.3-1.6-0.20.2-0.40.3-0.30.42.1-1.71.4-1.1
Locomotion distance, session 81.92.86.40.10.6-0.6-0.50.6-1.31.01.40.22.3-2.32.1-2.02.0-2.11.9-2.52.0-2.5
Degree of sensitization distance0.40.41.80.7-0.30.60.4-0.40.2-0.3-0.1-1.00.2-0.20.00.0-0.0-0.01.3-0.81.3-0.9
Degree of sensitization stereotypy0.60.71.10.8-0.80.90.7-0.70.9-0.7-0.9-1.0-0.90.9-1.01.1-1.11.00.30.5-0.00.5
Conditioned locomotion1.92.23.61.2-1.31.31.5-1.61.4-1.6-1.5-0.5-1.71.7-1.81.7-1.71.8-1.01.3-1.51.9
Cocaine response after cond. corrected0.40.62.0-0.60.6-0.7-0.50.4-0.70.70.61.30.4-0.40.4-0.60.6-0.4-1.10.7-1.40.9
Cocaine response after cond. not corrected0.40.61.11.0-1.00.91.0-1.10.8-0.9-0.8-0.3-0.80.8-0.70.6-0.60.8-0.10.4-0.60.8
Cocaine response before conditioning6.17.312.83.1-3.03.32.9-2.83.3-3.1-3.2-3.6-2.72.7-2.72.8-2.82.72.0-0.11.6-0.2
Saline control response0.60.82.1-0.2-0.10.3-0.00.00.9-0.5-1.0-0.9-1.41.4-1.21.4-1.41.2-0.50.9-0.20.7
Bone: connectivity density2.03.14.8-1.21.3-1.5-1.81.9-1.52.11.60.32.0-2.02.1-1.81.8-2.21.5-1.72.0-2.2
Bone: cortical apparent density0.40.62.1-0.90.6-0.5-0.60.5-0.00.2-0.10.6-0.60.6-0.60.6-0.60.5-1.31.4-1.21.0
Bone: cortical area0.91.42.51.1-1.31.41.1-1.11.6-1.5-1.6-1.3-1.41.4-1.21.2-1.21.20.9-0.21.0-0.3
Bone: cortical porosity0.10.10.20.1-0.20.20.1-0.10.3-0.2-0.3-0.4-0.40.4-0.40.3-0.30.40.10.10.10.0
Bone: cortical porosity0.40.51.50.7-0.70.80.6-0.60.8-0.7-0.8-1.2-0.60.6-0.50.3-0.30.50.9-0.60.9-0.5
Bone: cortical thickness0.71.23.4-0.90.2-0.1-0.30.30.7-0.4-0.80.3-1.71.7-1.31.3-1.31.2-1.31.9-1.01.1
Bone: cortical thickness1.01.23.6-1.71.4-1.2-1.21.1-0.70.60.61.2-0.50.5-0.20.5-0.50.2-1.91.7-1.51.2
Bone: cortical tissue density0.30.51.9-0.90.5-0.5-0.50.5-0.00.2-0.10.6-0.50.5-0.50.6-0.60.5-1.31.4-1.11.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.10.1-0.2-0.20.2-0.20.30.20.30.3-0.30.3-0.40.4-0.30.1-0.0-0.1-0.1
Condit. Reinf. active-inactive response ratio0.40.52.1-0.2-0.2-0.00.1-0.10.3-0.1-0.30.6-0.60.6-0.60.5-0.50.6-1.11.3-1.41.2
Condit. Reinf. active responses0.50.60.9-0.70.9-0.9-0.70.7-0.90.90.90.91.0-1.00.9-1.01.0-0.9-0.2-0.3-0.1-0.3
Condit. Reinf. inactive responses2.43.14.8-1.92.2-2.0-1.91.9-2.11.92.01.61.9-1.91.9-1.91.9-1.9-0.2-0.70.4-1.1
Incentive salience index mean0.20.30.80.4-0.2-0.10.2-0.3-0.30.20.30.60.9-0.90.7-0.90.9-0.70.2-0.8-0.1-0.3
Condit. Reinf. lever presses1.11.63.90.30.1-0.50.1-0.2-1.00.61.11.42.0-2.01.8-1.91.9-1.70.3-1.90.1-0.7
Condit. Reinf. active minus inactive responses0.81.22.11.2-1.01.41.1-1.11.3-1.2-1.3-1.5-1.21.2-1.21.0-1.01.10.8-0.10.6-0.0
Condit. Reinf. active-inactive response ratio1.52.33.51.8-1.71.91.8-1.81.8-1.8-1.8-1.4-1.61.6-1.71.6-1.61.70.50.3-0.10.7
Condit. Reinf. active responses0.20.21.00.30.10.20.00.00.10.0-0.0-0.60.2-0.20.2-0.30.3-0.21.0-0.91.0-0.9
Condit. Reinf. inactive responses0.71.11.7-0.91.1-1.0-1.01.0-1.01.01.10.51.1-1.11.3-1.31.3-1.30.4-0.90.8-1.1
Condit. Reinf. lever presses1.42.05.5-0.41.0-0.7-0.91.0-0.91.01.0-0.51.5-1.51.5-1.61.6-1.51.7-2.32.2-2.1
Condit. Reinf. lever reinforcers received0.30.41.40.20.10.1-0.00.1-0.10.10.1-0.50.4-0.40.5-0.60.6-0.51.1-1.11.2-1.1
Conditioned reinforcement - actives0.10.52.0-0.20.20.3-0.10.10.8-0.5-0.8-1.4-1.11.1-1.00.9-0.90.90.10.80.50.1
Conditioned reinforcement - inactives0.10.31.6-0.50.4-0.1-0.40.40.4-0.3-0.5-1.3-0.80.8-0.60.5-0.50.6-0.20.20.40.2
Conditioned locomotion0.30.41.80.4-0.50.60.4-0.40.9-0.6-0.8-1.3-0.60.6-0.60.6-0.60.60.4-0.20.60.4
Patch foraging indifference point 0 sec0.30.93.7-0.91.2-0.6-1.31.4-0.51.00.5-1.00.4-0.40.3-0.10.1-0.41.40.11.9-1.5
Patch foraging indifference point AUC0.71.73.31.0-1.11.41.2-1.11.6-1.5-1.6-1.4-1.81.8-1.51.4-1.41.50.50.20.60.2
Delay disc. indifference point, 0s delay1.01.11.71.1-1.21.11.3-1.31.2-1.1-1.2-0.5-1.21.2-1.21.1-1.11.2-0.40.6-1.01.0
Delay disc. indifference point, 16s delay0.50.82.6-0.80.3-0.2-0.50.60.4-0.1-0.5-0.6-1.31.3-1.01.2-1.21.0-0.91.6-0.50.7
Delay disc. indifference point, 2s delay2.02.23.21.4-1.41.61.6-1.61.5-1.7-1.6-1.6-1.71.7-1.81.6-1.61.8-0.20.8-0.71.1
Delay disc. indifference point, 24s delay0.30.51.00.2-0.40.50.1-0.00.8-0.3-0.8-1.0-0.80.8-0.91.0-1.00.80.40.90.40.0
Delay disc. indifference point, 4s delay3.63.85.51.8-2.02.12.1-2.12.3-2.2-2.3-1.8-2.32.3-2.32.2-2.22.3-0.11.0-0.61.2
Delay disc. indifference point, 8s delay0.30.52.50.3-0.40.60.2-0.20.9-0.3-0.9-1.6-0.40.4-0.60.8-0.80.60.70.11.0-0.5
Indifference point function ln k0.20.51.30.4-0.10.10.1-0.1-0.30.10.4-0.41.0-1.00.7-0.80.8-0.71.0-1.10.8-1.0
Indifference point function log k0.20.51.30.4-0.10.10.1-0.1-0.30.10.4-0.41.0-1.00.7-0.80.8-0.71.0-1.10.8-1.0
Patch foraging total patch changes 0 sec0.30.94.0-1.01.2-0.6-1.41.5-0.40.90.4-1.20.2-0.20.20.1-0.1-0.31.40.22.0-1.5
Patch foraging total patch changes 12 sec0.30.41.3-1.00.9-0.4-1.01.0-0.00.4-0.0-0.5-0.70.7-0.30.2-0.20.20.50.51.1-0.8
Patch foraging total patch changes 18 sec0.71.64.3-2.01.9-1.7-2.02.1-1.61.71.50.90.7-0.70.8-0.40.4-0.9-0.30.80.3-0.4
Patch foraging total patch changes 24 sec0.62.16.7-2.22.1-1.8-2.52.6-1.22.01.2-0.10.6-0.60.9-0.70.7-1.00.50.21.5-1.2
Patch foraging total patch changes 6 sec0.40.62.7-1.10.9-0.4-1.11.20.00.5-0.1-0.7-0.80.8-0.60.7-0.70.50.31.60.8-0.4
Patch foraging time to switch 0 sec0.52.06.1-1.51.1-1.5-1.11.0-1.31.11.22.30.5-0.50.5-0.30.3-0.4-2.51.9-2.41.8
Patch foraging water rate 0 sec0.41.47.00.4-0.00.7-0.00.20.7-0.4-0.7-2.3-0.60.6-0.40.4-0.40.32.4-0.92.6-2.0
Patch foraging water rate 12 sec0.00.20.6-0.70.6-0.6-0.80.8-0.30.60.3-0.10.1-0.10.2-0.40.4-0.30.1-0.20.5-0.4
Patch foraging water rate 18 sec0.10.20.90.30.10.40.2-0.10.3-0.2-0.3-1.0-0.10.1-0.2-0.10.10.20.7-0.40.9-0.6
Patch foraging water rate 24 sec0.20.30.60.2-0.30.50.3-0.30.4-0.5-0.5-0.5-0.80.8-0.70.7-0.70.7-0.00.50.30.1
Patch foraging water rate 6 sec0.20.30.8-0.90.7-0.7-0.80.9-0.30.60.3-0.2-0.00.00.3-0.60.6-0.4-0.2-0.10.3-0.1
Seeking ratio, delayed vs. immediate footshock0.40.61.80.7-0.70.70.8-0.90.7-0.8-0.80.1-0.80.8-0.80.6-0.60.8-0.50.3-0.81.3
Distance traveled before self-admin0.30.62.50.9-1.00.80.9-0.90.8-0.7-0.7-1.0-0.20.20.00.0-0.00.00.9-1.60.9-0.9
Distance traveled after self-admin0.50.92.71.2-1.71.11.3-1.31.2-1.1-1.1-0.4-0.70.7-0.70.9-0.90.80.2-0.4-0.10.3
Extensor digitorum longus weight0.62.310.91.4-1.01.10.5-0.40.7-0.3-0.6-2.60.3-0.30.2-0.10.1-0.23.3-1.83.3-2.5
Bone: elastic displacement0.20.30.9-0.2-0.2-0.0-0.10.10.40.1-0.4-0.2-0.60.6-0.50.6-0.60.5-0.60.9-0.70.9
Bone: elastic work0.81.12.20.3-1.00.60.6-0.71.2-0.8-1.2-0.4-1.51.5-1.11.3-1.31.1-0.81.3-0.91.2
Bone: endosteal estimation3.58.618.34.3-4.04.03.9-3.93.4-3.5-3.3-3.2-1.91.9-2.22.3-2.32.32.5-1.01.5-0.4
Bone: endosteal perimeter1.53.89.63.0-2.42.32.3-2.21.6-1.8-1.4-2.40.1-0.1-0.20.1-0.10.23.1-2.72.7-1.8
Epididymis fat weight1.89.126.2-5.03.5-3.4-3.83.7-1.92.41.53.2-1.21.2-0.51.0-1.00.5-4.85.1-3.52.9
Delta time in closed arm before/after self-admin0.10.10.40.1-0.20.30.1-0.10.3-0.3-0.3-0.2-0.60.6-0.60.5-0.50.60.10.40.10.2
Delta time in open arm before/after self-admin0.50.62.70.4-0.70.50.3-0.30.8-0.4-0.8-1.6-0.40.4-0.30.4-0.40.31.0-1.11.4-1.0
Diff in mean of infusions in LGA sessions2.13.75.5-1.81.9-2.2-1.81.8-2.32.12.41.92.2-2.22.2-2.42.4-2.2-1.1-1.0-0.8-0.1
Delay discount exponential model param1.41.93.3-0.91.2-1.3-1.11.0-1.61.31.71.81.7-1.71.8-1.81.8-1.70.1-1.10.2-0.8
Extinction: sum of active levers before priming1.11.64.2-1.31.2-1.5-1.00.9-1.41.11.32.01.1-1.11.3-1.41.4-1.2-1.60.0-1.50.7
Active lever presses in extinction session 61.71.77.2-1.71.1-1.5-1.00.9-0.70.70.61.9-0.20.20.3-0.60.6-0.2-2.71.2-2.61.7
Bone: final force1.32.15.00.3-1.01.00.8-0.81.5-1.4-1.6-0.3-2.22.2-1.92.1-2.11.9-0.81.7-0.71.1
Bone: final moment1.01.74.10.5-0.91.10.8-0.71.4-1.3-1.5-0.8-2.02.0-1.71.8-1.81.7-0.11.20.00.4
Food consumed during 24 hour testing period0.61.22.81.6-1.61.41.6-1.71.3-1.4-1.3-0.7-0.90.9-0.90.9-0.91.00.00.1-0.40.7
Glucose2.43.913.32.6-1.71.61.6-1.50.5-0.7-0.3-2.41.5-1.51.0-1.11.1-1.03.7-3.53.1-2.4
Heart weight1.93.15.61.4-1.51.91.3-1.22.0-1.8-2.1-2.0-2.12.1-2.12.4-2.42.11.01.40.70.3
Delay discount hyperbolic model param1.51.93.3-0.91.1-1.3-1.11.1-1.61.31.61.71.7-1.71.8-1.81.8-1.80.2-1.10.4-0.9
Intermittent access intake day 1-15 change0.00.00.30.00.10.10.2-0.20.1-0.1-0.1-0.30.0-0.0-0.1-0.20.20.1-0.3-0.2-0.10.5
Intermittent access intake escalation0.10.31.3-0.1-0.00.10.3-0.30.3-0.4-0.3-0.1-0.50.5-0.60.4-0.40.6-0.90.6-0.81.1
Intermittent access intake escalation 20.30.61.71.0-0.70.90.9-0.90.7-0.8-0.6-1.3-0.00.0-0.20.0-0.00.21.1-1.01.1-0.6
Intermitt. access day 1 inactive lever presses0.00.51.41.2-1.20.91.2-1.20.8-0.9-0.7-0.8-0.00.0-0.10.1-0.10.20.4-1.00.10.2
Intermitt. access day 15 inactive lever presses0.21.03.81.3-1.31.21.1-1.11.0-0.9-1.0-1.9-0.30.3-0.80.8-0.80.71.0-0.50.8-0.0
Intermitt. access escalation Index0.61.96.7-1.01.0-1.4-0.80.7-1.41.11.42.61.4-1.41.5-1.61.6-1.5-1.3-0.4-1.50.9
Intermittent access day 1 total infusions0.20.51.7-1.31.0-1.0-1.11.1-0.50.80.50.50.0-0.00.2-0.20.2-0.2-0.80.4-0.3-0.0
Intermittent access day 15 total infusions0.20.62.5-0.80.4-0.3-0.30.30.20.0-0.30.3-0.90.9-0.70.5-0.50.7-1.61.2-1.31.2
Intermittent access terminal intake (last 3 days)0.20.40.8-0.70.4-0.2-0.40.40.30.1-0.4-0.6-0.80.8-0.80.7-0.70.8-0.80.9-0.40.6
Intermittent access total infusions0.20.30.6-0.60.3-0.2-0.30.40.40.0-0.4-0.5-0.70.7-0.70.6-0.60.6-0.70.7-0.30.4
Intermittent access day 1 locomotion0.20.31.1-0.1-0.30.10.3-0.30.4-0.3-0.50.1-0.60.6-0.60.6-0.60.6-1.00.5-1.01.0
Intermittent access day 15 total locomotion0.83.24.71.3-1.61.71.8-1.82.1-2.0-2.1-0.9-2.12.1-2.12.1-2.12.2-0.91.3-1.11.6
Intermittent access total locomotion2.12.63.91.1-1.41.51.6-1.61.8-1.7-1.9-0.9-1.91.9-2.01.9-1.92.0-0.91.0-1.01.5
Intermittent access standard deviation0.21.25.20.2-0.10.80.3-0.21.3-1.0-1.3-2.3-1.41.4-1.31.0-1.01.20.70.21.3-0.5
Left kidney weight1.511.818.12.9-3.63.73.2-3.14.1-3.8-4.1-3.0-4.34.3-4.14.2-4.24.10.62.10.21.4
Right kidney weight2.416.424.03.5-4.24.43.9-3.94.8-4.6-4.9-3.6-4.84.8-4.84.9-4.94.80.72.60.11.7
Cocaine induced anxiety0.20.62.51.1-0.70.60.8-0.80.1-0.3-0.0-0.70.8-0.80.5-0.80.8-0.51.2-1.61.0-0.8
Post-drug Anxiety0.40.42.00.4-0.20.00.3-0.4-0.4-0.00.4-0.10.9-0.90.7-1.01.0-0.70.3-1.40.2-0.8
Baseline Anxiety1.11.94.7-1.91.7-1.8-1.71.6-1.71.31.62.20.8-0.80.9-1.01.0-0.9-1.60.5-1.30.5
Tail length3.317.928.95.2-5.35.45.1-5.05.2-5.1-5.2-4.4-4.14.1-4.13.8-3.84.12.50.11.60.3
Length with tail6.327.845.56.4-6.46.76.2-6.06.5-6.3-6.4-5.9-5.05.0-5.04.7-4.75.03.90.12.9-0.5
Length without tail2.714.421.94.3-4.74.74.4-4.44.7-4.7-4.6-3.3-3.93.9-4.13.8-3.84.11.31.20.50.9
Times rat made contact with spout2.22.54.4-2.11.9-2.1-2.02.0-1.92.01.91.71.4-1.41.5-1.51.5-1.5-1.10.1-0.60.1
Lifetime Intake0.30.40.9-0.40.00.1-0.10.20.6-0.2-0.7-0.6-1.01.0-0.90.8-0.80.8-0.60.8-0.20.3
Liver weight, left1.93.48.32.9-2.92.52.8-2.82.1-2.4-2.0-1.3-0.90.9-1.11.0-1.01.11.4-0.90.7-0.3
Liver weight, right4.37.515.63.7-4.03.63.7-3.73.3-3.5-3.2-2.4-2.02.0-2.42.5-2.52.51.20.30.30.7
Locomotor activity2.54.08.62.8-2.42.52.3-2.31.9-2.0-1.8-2.9-0.70.7-0.91.0-1.00.92.8-2.02.5-1.5
Locomotor testing distance0.71.86.31.6-1.31.31.0-0.90.7-0.6-0.6-2.40.3-0.30.00.2-0.2-0.12.5-1.82.5-1.7
Locomotor testing rearing0.31.32.61.6-1.51.51.4-1.41.1-1.1-1.1-1.4-0.60.6-0.60.9-0.90.61.4-0.91.2-0.8
Locomotion in novel chamber0.20.20.60.3-0.40.50.3-0.30.7-0.5-0.6-0.5-0.80.8-0.40.1-0.10.40.50.00.5-0.5
Locomotion in novel chamber post-restriction0.20.61.30.5-0.80.70.6-0.50.8-0.8-0.8-0.7-1.11.1-1.00.9-0.91.00.00.5-0.10.3
Fecal boli incidents, locomotor time 10.30.91.6-0.60.8-0.8-0.90.9-0.91.21.0-0.01.1-1.11.1-1.21.2-1.10.6-0.90.7-0.9
Change in fecal boli incidents, locomotor task1.51.62.51.0-1.11.11.3-1.41.2-1.5-1.2-0.4-1.31.3-1.41.4-1.41.4-1.01.3-1.51.6
Time >=10cm from walls, locomotor time 10.91.22.91.5-1.71.31.6-1.61.2-1.3-1.2-0.9-0.80.8-0.91.0-1.01.00.00.1-0.30.6
Bouts of movement, locomotor time 10.81.14.90.4-0.00.2-0.10.10.00.30.1-1.30.9-0.90.7-0.70.7-0.71.9-1.72.2-1.9
Total resting periods, locomotor time 10.50.52.30.7-0.30.50.3-0.30.3-0.2-0.2-1.00.4-0.40.2-0.20.2-0.21.4-1.21.5-1.2
Rest time, locomotor task time 10.71.12.71.5-1.41.41.6-1.61.2-1.4-1.2-0.5-0.80.8-1.00.7-0.71.00.00.0-0.40.5
Distance moved, locomotor task time 10.10.21.0-0.40.4-0.2-0.60.7-0.20.30.2-0.3-0.10.10.10.1-0.1-0.10.80.21.0-0.7
Vertical activity count, locomotor time 10.00.21.2-0.40.4-0.2-0.60.6-0.20.20.2-0.70.0-0.00.2-0.20.2-0.30.7-0.31.1-0.8
Time >=10cm from walls, locomotor time 20.30.91.81.2-1.41.11.0-1.01.2-1.0-1.1-1.3-0.70.7-0.80.8-0.80.80.9-0.20.7-0.3
Bouts of movement, locomotor time 20.62.04.11.8-2.01.71.8-1.82.0-1.7-2.0-1.1-1.31.3-1.00.9-0.91.10.9-0.60.6-0.4
Total resting periods, locomotor time 20.52.04.32.0-2.11.81.9-1.92.0-1.7-1.9-1.0-1.11.1-0.90.7-0.70.91.2-0.90.9-0.6
Rest time, locomotor task time 20.61.13.82.0-1.51.41.9-1.90.7-1.3-0.7-0.10.2-0.2-0.0-0.20.20.10.8-1.40.2-0.4
Distance moved, locomotor task time 20.30.41.6-1.00.8-0.4-1.01.1-0.20.50.2-0.1-0.70.7-0.50.7-0.70.40.11.30.5-0.1
Vertical activity count, locomotor time 20.10.20.8-0.80.6-0.6-0.90.9-0.40.40.40.2-0.10.10.2-0.00.0-0.20.10.50.5-0.3
Light reinforcement 10.00.10.3-0.50.4-0.4-0.50.60.00.3-0.00.1-0.40.4-0.10.0-0.00.1-0.20.50.10.2
Light reinforcement 21.32.94.61.8-1.82.01.7-1.62.1-1.8-2.1-1.9-2.02.0-1.91.7-1.71.90.80.50.70.5
Bone: marrow area3.48.317.64.2-3.93.93.9-3.83.3-3.5-3.2-3.1-1.91.9-2.22.3-2.32.32.4-0.91.4-0.3
Bone: maximum diameter1.32.66.52.3-1.92.01.9-1.81.5-1.6-1.4-2.0-0.30.3-0.40.3-0.30.42.5-2.12.3-1.5
Bone: maximum force1.22.34.80.8-1.41.41.2-1.11.7-1.6-1.8-0.8-2.22.2-1.92.1-2.11.8-0.21.3-0.20.6
Bone: maximum moment1.12.13.91.0-1.41.51.1-1.11.8-1.6-1.8-1.4-2.02.0-1.71.8-1.81.60.60.80.6-0.1
Mean time between licks in bursts0.31.74.52.1-1.61.61.7-1.71.1-1.3-1.0-1.70.1-0.1-0.20.1-0.10.21.8-1.71.4-1.0
Mean num. licks in bursts0.51.43.6-1.91.6-1.6-1.71.7-1.21.41.21.40.4-0.40.9-1.01.0-0.9-0.80.8-0.3-0.1
Cd content in liver0.20.20.8-0.70.7-0.5-0.90.9-0.30.50.3-0.30.1-0.10.2-0.10.1-0.30.40.50.6-0.6
Co content in liver0.30.31.5-0.90.6-0.4-0.70.7-0.10.30.10.2-0.50.5-0.40.5-0.50.4-0.71.2-0.40.4
Cu content in liver1.92.35.7-2.42.0-2.1-2.32.3-1.61.91.51.40.9-0.91.4-1.11.1-1.4-0.8-0.10.1-0.4
Fe content in liver0.80.93.5-0.50.1-0.2-0.0-0.00.3-0.1-0.40.8-1.01.0-0.90.8-0.80.9-1.81.6-1.71.9
K content in liver0.80.81.3-1.01.0-1.1-1.11.1-1.11.11.10.81.0-1.01.0-0.70.7-1.0-0.3-0.30.1-0.2
Mg content in liver0.40.51.70.10.1-0.2-0.10.1-0.60.40.6-0.11.0-1.00.9-0.70.7-0.90.6-1.31.0-0.7
Mn content in liver1.11.35.81.3-0.60.50.8-0.8-0.3-0.00.4-0.51.4-1.41.1-1.11.1-1.11.6-2.41.4-1.2
Na content in liver0.30.31.1-1.00.7-0.7-0.80.8-0.50.60.40.5-0.10.1-0.00.2-0.2-0.0-0.90.6-0.30.6
Rb content in liver0.50.60.8-0.80.7-0.8-0.90.9-0.60.80.60.20.7-0.70.9-0.70.7-0.90.4-0.90.9-0.8
Se content in liver1.21.43.92.0-1.71.51.7-1.71.3-1.2-1.2-1.3-0.30.3-0.40.3-0.30.41.4-1.20.9-0.5
Sr content in liver0.70.61.40.8-1.00.91.1-1.11.0-1.2-1.0-0.2-0.80.8-0.70.6-0.60.8-0.30.0-0.50.7
Zn content in liver0.40.42.20.2-0.10.0-0.10.20.10.20.0-0.60.4-0.40.6-0.40.4-0.61.3-0.81.5-1.3
Bone: minimum diameter1.42.86.82.6-2.32.12.3-2.21.8-1.8-1.7-1.8-0.50.5-0.60.5-0.50.62.0-2.01.6-0.9
Time in familiar zone, hab. session 13.13.56.2-2.52.2-2.4-2.32.3-2.42.22.42.21.6-1.61.6-1.41.4-1.6-1.40.7-0.80.1
Time in novel zone, hab. session 13.43.810.52.4-2.02.41.8-1.72.3-1.9-2.2-3.2-1.31.3-1.31.1-1.11.22.8-1.52.5-1.5
Total zone transitions, hab. session 10.81.11.7-0.81.0-1.0-1.11.1-1.01.21.10.31.3-1.31.3-1.11.1-1.30.7-1.01.0-1.1
Total locomotion distance, hab. session 10.60.81.2-0.90.9-1.0-1.11.1-1.01.11.00.71.0-1.01.0-0.90.9-1.00.0-0.50.3-0.6
Locomotion velocity, hab. session 10.50.71.2-1.10.9-1.1-1.01.0-1.01.00.91.00.8-0.80.8-0.70.7-0.8-0.60.0-0.4-0.0
Time in familiar zone, hab. session 20.91.02.7-1.31.2-1.3-1.11.0-1.31.11.21.60.7-0.70.9-0.80.8-0.9-1.00.1-0.60.1
Time in novel zone, hab. session 20.91.03.21.1-0.91.20.8-0.71.2-0.9-1.2-1.8-0.80.8-1.00.8-0.81.01.1-0.00.8-0.2
Total zone transitions, hab. session 20.20.30.5-0.70.7-0.6-0.60.6-0.60.50.60.60.5-0.50.3-0.30.3-0.3-0.60.3-0.50.3
Total locomotion distance, hab. session 21.11.42.2-1.31.3-1.4-1.31.3-1.51.51.51.01.4-1.41.3-1.21.2-1.3-0.3-0.3-0.1-0.4
Locomotion velocity, hab. session 21.21.62.4-1.31.4-1.5-1.41.4-1.61.51.61.11.5-1.51.4-1.31.3-1.4-0.4-0.4-0.1-0.4
Novel to familiar place preference ratio0.10.10.4-0.10.00.1-0.20.30.20.0-0.3-0.6-0.30.3-0.40.3-0.30.30.30.60.2-0.0
Novelty place preference0.20.30.80.2-0.30.40.1-0.10.6-0.3-0.6-0.9-0.60.6-0.70.6-0.60.60.40.60.20.1
Time in novel zone, NPP test0.40.51.30.5-0.60.70.3-0.30.9-0.5-0.9-1.2-0.80.8-0.90.8-0.80.80.60.60.30.0
Total zone transitions, NPP test1.01.42.5-0.60.8-0.9-1.11.2-1.01.31.1-0.21.4-1.41.3-1.21.2-1.41.3-1.21.5-1.6
Total locomotion distance, NPP test1.01.32.4-1.21.3-1.3-1.51.5-1.31.61.30.41.3-1.31.2-1.11.1-1.30.3-0.40.6-0.9
Locomotion velocity, NPP test1.72.54.2-1.71.7-1.8-1.91.9-1.82.01.80.91.8-1.81.7-1.61.6-1.80.1-0.60.5-1.0
Intraocular pressure0.50.81.4-0.51.0-0.6-0.80.8-0.80.70.8-0.10.8-0.81.0-1.01.0-1.00.8-1.21.1-1.2
Delta distance traveled before/after self-admin1.11.22.70.6-1.10.90.8-0.71.0-0.8-1.0-0.3-1.11.1-1.41.6-1.61.4-0.51.5-0.81.2
Delta ambulatory time before/after self-admin0.61.01.80.8-1.10.90.9-0.90.8-0.8-0.80.0-1.01.0-1.21.4-1.41.2-0.41.3-0.81.1
Parametrial fat weight0.71.62.80.8-1.21.21.1-1.11.4-1.4-1.5-0.5-1.71.7-1.51.6-1.61.5-0.41.0-0.60.9
Pavlov. Cond. lever latency0.91.13.6-1.91.4-1.2-1.41.4-0.60.60.51.0-0.80.8-0.20.3-0.30.2-1.61.7-1.10.8
Pavlov. Cond. magazine entry latency0.60.82.71.0-0.50.20.8-0.9-0.4-0.00.40.61.4-1.41.1-1.21.2-1.00.4-1.6-0.2-0.3
Pavlov. Cond. change in total contacts1.41.54.22.0-1.71.71.8-1.81.3-1.4-1.3-1.2-0.50.5-0.90.8-0.81.00.8-0.10.20.3
Pavlov. Cond. index score0.70.92.81.6-1.00.71.3-1.30.0-0.40.10.21.2-1.20.8-0.80.8-0.70.7-1.70.0-0.3
Pavlov. Cond. latency score0.70.93.01.7-1.20.91.4-1.50.3-0.6-0.2-0.11.0-1.00.5-0.60.6-0.50.9-1.70.2-0.3
Pavlov. Cond. lever contacts0.91.13.71.9-1.41.31.5-1.50.6-0.7-0.6-1.00.6-0.60.1-0.20.2-0.11.4-1.50.9-0.6
Pavlov. Cond. magazine entry number0.81.02.9-0.50.20.3-0.40.50.8-0.4-0.9-1.1-1.71.7-1.31.4-1.41.20.11.30.60.0
Pavlov. Cond. intertrial magazine entries0.81.02.9-1.61.6-1.3-1.61.7-0.91.20.90.60.2-0.20.5-0.70.7-0.5-0.20.50.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.70.82.81.4-0.90.51.1-1.1-0.2-0.20.20.41.4-1.40.9-0.90.9-0.80.7-1.7-0.0-0.4
Pavlov. Cond. response bias0.60.82.11.3-0.80.51.0-1.1-0.2-0.10.30.41.4-1.40.9-1.01.0-0.80.6-1.4-0.1-0.2
Pavlov. Cond. lever latency0.60.81.50.8-1.00.81.0-1.00.7-0.9-0.80.2-0.90.9-0.90.9-0.90.9-0.71.0-1.21.2
Pavlov. Cond. magazine entry latency0.20.30.60.7-0.70.70.8-0.80.8-0.7-0.8-0.5-0.50.5-0.50.6-0.60.60.1-0.20.10.1
Pavlov. Cond. change in total contacts0.00.10.40.0-0.10.2-0.00.10.3-0.1-0.3-0.6-0.30.3-0.30.3-0.30.30.30.10.4-0.2
Pavlov. Cond. index score0.10.20.90.2-0.00.20.0-0.00.2-0.0-0.2-0.70.1-0.10.1-0.10.1-0.10.7-0.70.9-0.7
Pavlov. Cond. latency score0.00.10.30.00.00.1-0.00.00.2-0.0-0.2-0.40.0-0.00.0-0.00.0-0.00.4-0.50.6-0.4
Pavlov. Cond. lever contacts0.40.61.4-0.60.7-0.6-0.80.9-0.50.70.5-0.40.7-0.70.7-0.60.6-0.70.8-0.91.2-1.1
Pavlov. Cond. magazine entry number0.20.30.7-0.50.5-0.6-0.50.5-0.70.50.70.90.5-0.50.6-0.70.7-0.6-0.40.0-0.50.1
Pavlov. Cond. intertrial magazine entries0.20.41.70.7-0.20.20.5-0.5-0.3-0.10.30.10.8-0.80.6-0.90.9-0.60.7-1.30.4-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.21.10.2-0.00.2-0.00.10.10.1-0.1-0.70.2-0.20.1-0.10.1-0.20.9-0.81.1-0.8
Pavlov. Cond. response bias0.30.41.60.10.1-0.0-0.20.2-0.10.30.1-0.80.6-0.60.4-0.40.4-0.41.1-1.01.3-1.1
Time in closed arm before self-admin0.10.20.8-0.40.5-0.4-0.20.2-0.50.10.40.60.1-0.10.10.1-0.1-0.1-0.80.7-0.90.6
Time in closed arm after self-admin1.01.24.6-0.60.1-0.1-0.10.10.2-0.4-0.30.7-1.21.2-1.11.2-1.21.1-1.72.1-1.61.7
Time in open arm before self-admin0.20.21.10.20.3-0.10.1-0.1-0.4-0.10.41.00.4-0.40.5-0.80.8-0.50.2-0.3-0.3-0.1
Time in open arm after self-admin0.60.62.70.5-0.20.20.2-0.2-0.1-0.10.2-0.10.7-0.70.8-0.90.9-0.81.3-1.71.2-1.4
Bone: periosteal estimation2.76.310.63.3-3.23.33.1-3.03.1-3.0-3.0-2.8-2.12.1-2.12.2-2.22.12.1-0.71.5-0.5
Bone: periosteal perimeter1.42.85.52.3-2.22.22.1-2.01.9-2.0-1.8-1.9-1.01.0-1.01.1-1.11.01.9-1.41.6-0.9
Bone: post-yield work1.32.38.81.9-1.21.41.2-1.10.8-0.9-0.6-1.80.5-0.50.4-0.40.4-0.43.0-2.52.7-2.5
Progressive ratio test 1 active lever presses0.40.62.9-0.90.4-0.5-0.40.40.00.1-0.10.8-0.70.7-0.50.4-0.40.5-1.71.2-1.51.2
Progressive ratio test 1 breakpoint0.40.62.6-0.80.4-0.5-0.40.30.10.1-0.10.7-0.70.7-0.50.5-0.50.5-1.61.2-1.41.2
Progressive ratio test 1 inactive lever presses0.30.72.7-1.71.5-1.2-1.51.5-0.70.90.70.20.1-0.10.2-0.30.3-0.3-0.80.5-0.20.5
Progressive ratio test 2 active lever presses0.60.83.0-1.41.2-1.1-1.00.9-0.60.80.51.0-0.20.20.0-0.20.2-0.0-1.70.8-1.40.7
Progressive ratio test 2 breakpoint0.70.93.6-1.51.1-1.1-1.00.9-0.60.70.51.0-0.20.2-0.0-0.20.20.0-1.91.0-1.60.9
Progressive ratio test 2 inactive lever presses0.00.10.50.00.10.20.2-0.20.3-0.4-0.3-0.7-0.50.5-0.50.4-0.40.5-0.20.2-0.00.1
Incentive Sensitization - Responses0.30.91.6-1.31.3-1.3-1.01.0-1.01.01.01.00.6-0.60.7-1.01.0-0.7-1.30.1-1.00.2
Incentive Sensitization - Breakpoint0.40.91.8-1.31.3-1.3-1.11.0-1.01.01.01.10.6-0.60.7-1.01.0-0.7-1.30.1-1.10.2
Sum of active levers in priming session hrs 5-60.10.10.3-0.20.2-0.4-0.20.2-0.50.40.50.10.4-0.40.5-0.50.5-0.5-0.1-0.5-0.1-0.1
Progressive ratio1.44.28.80.8-1.31.41.5-1.61.6-1.9-1.80.4-2.52.5-2.62.3-2.32.6-2.12.5-2.53.0
Food seeking constrained by brief footshock0.00.10.3-0.00.2-0.0-0.20.20.00.0-0.00.1-0.20.20.1-0.20.2-0.10.5-0.00.3-0.5
Seeking ratio, punishment vs. effort1.53.48.1-0.71.1-1.2-1.51.5-1.31.71.4-0.51.9-1.92.2-2.02.0-2.32.1-2.22.4-2.8
Retroperitoneal fat weight0.41.82.81.0-1.21.41.2-1.11.6-1.5-1.7-1.0-1.61.6-1.71.6-1.61.70.21.10.10.6
Reaction time number correct0.20.62.9-1.01.1-0.6-0.90.9-0.50.50.50.3-0.40.4-0.40.4-0.40.4-0.81.7-0.60.7
Reaction time mean minus median0.42.67.02.6-2.52.12.3-2.31.5-1.8-1.3-1.6-0.10.1-0.20.0-0.00.32.0-2.21.4-1.1
Reaction time mean minus median AUC0.32.25.02.2-2.01.71.8-1.81.3-1.5-1.1-1.80.0-0.0-0.10.0-0.00.22.1-2.21.7-1.4
Reaction time num false alarms0.10.20.50.7-0.60.60.5-0.50.2-0.3-0.2-0.50.0-0.0-0.20.5-0.50.20.50.10.3-0.0
Reaction time num false alarms AUC0.10.20.80.9-0.60.70.6-0.60.3-0.4-0.2-0.70.0-0.0-0.20.4-0.40.20.8-0.10.5-0.2
Reaction time trials correct on left0.20.62.9-1.01.1-0.6-0.90.9-0.50.50.50.3-0.40.4-0.40.4-0.40.4-0.81.7-0.60.7
Reaction time trials on left0.10.52.8-0.91.0-0.5-0.80.8-0.50.40.40.3-0.50.5-0.50.5-0.50.4-0.81.7-0.60.7
Reaction time mean1.22.68.32.4-1.91.61.8-1.70.9-1.0-0.7-2.00.8-0.80.5-0.40.4-0.42.7-2.92.1-1.9
Reaction time mean AUC1.22.88.32.5-2.01.81.9-1.81.0-1.2-0.9-2.20.6-0.60.3-0.30.3-0.32.7-2.92.1-1.9
Median of all reaction times1.21.86.41.8-1.41.21.2-1.20.5-0.6-0.3-1.70.9-0.90.6-0.40.4-0.62.3-2.51.9-1.8
Reaction time omissions0.81.34.82.2-1.71.62.0-2.00.9-1.2-0.8-0.90.1-0.1-0.2-0.10.10.31.1-1.50.3-0.2
Reaction time false alarm rate0.50.72.01.4-1.11.01.0-1.00.6-0.6-0.5-1.00.3-0.30.00.1-0.1-0.01.4-1.21.0-0.8
Reaction time premature initiation rate0.40.61.20.6-0.80.70.7-0.71.0-0.8-1.0-0.6-1.11.1-1.00.8-0.81.0-0.20.7-0.30.7
Reaction time premature initiations0.30.93.20.1-0.20.40.2-0.20.7-0.5-0.7-0.4-1.31.3-1.31.2-1.21.3-0.71.8-0.91.2
Std. dev. reaction times1.03.38.62.9-2.62.32.5-2.51.7-1.9-1.6-2.1-0.10.1-0.30.2-0.20.42.4-2.41.6-1.4
Reaction time trials completed0.10.52.8-0.91.0-0.5-0.80.8-0.50.40.40.3-0.50.5-0.50.5-0.50.4-0.81.7-0.60.7
Reaction time trials AUC0.20.52.8-1.01.0-0.6-0.80.8-0.60.50.50.3-0.40.4-0.40.4-0.40.4-0.81.7-0.60.7
Run reversals in cocaine runway, females0.50.51.2-0.91.0-0.7-1.01.1-0.50.80.5-0.20.4-0.40.6-0.50.5-0.70.6-0.21.0-1.0
Run reversals in cocaine runway, males2.62.96.62.5-2.62.32.4-2.32.0-2.0-1.9-1.5-1.11.1-1.31.2-1.21.31.3-0.70.8-0.1
Latency to leave start box in cocaine runway0.10.10.60.00.4-0.10.1-0.2-0.30.00.30.10.2-0.2-0.10.0-0.00.1-0.60.4-0.80.5
Latency to leave start box in cocaine runway, F0.40.51.2-0.10.7-0.4-0.30.4-0.80.50.8-0.11.1-1.10.8-1.01.0-0.80.6-0.90.6-0.9
Latency to leave start box in cocaine runway, M1.81.73.90.4-0.50.70.9-1.00.9-1.1-0.9-0.0-1.31.3-1.51.6-1.61.5-1.71.9-2.01.9
Std. dev. time between licks in bursts0.91.74.92.2-1.71.71.9-1.91.2-1.5-1.2-1.3-0.20.2-0.40.2-0.20.41.6-1.61.0-0.8
Total sessions with >9 infusions0.30.40.9-0.4-0.1-0.0-0.10.10.5-0.2-0.6-0.1-0.80.8-0.70.9-0.90.7-0.90.9-0.70.7
Short access day 1 total inactive lever presses0.91.72.91.5-1.71.61.6-1.61.7-1.7-1.7-1.4-1.31.3-1.21.1-1.11.30.6-0.40.40.1
Short access day 10 total inactive lever presses0.21.22.9-0.40.7-0.8-0.50.5-1.10.81.10.51.6-1.61.5-1.71.7-1.50.3-1.70.5-0.4
Short access day 1 total infusions0.10.10.7-0.40.2-0.2-0.50.5-0.10.30.1-0.20.0-0.00.10.0-0.0-0.10.4-0.10.7-0.8
Short access day 10 total infusions0.10.20.6-0.40.1-0.1-0.30.30.3-0.0-0.3-0.3-0.50.5-0.50.7-0.70.5-0.50.8-0.3-0.1
Short access total infusions0.20.30.7-0.4-0.00.0-0.30.30.5-0.1-0.5-0.5-0.80.8-0.70.8-0.80.7-0.30.70.1-0.1
Short access day 1 locomotion0.50.81.4-0.80.9-0.9-1.01.1-0.81.00.90.41.2-1.21.0-0.70.7-1.00.3-0.40.6-1.1
Short access day 10 total locomotion0.31.22.11.4-1.51.41.4-1.41.4-1.4-1.4-1.3-0.90.9-0.90.8-0.80.90.7-0.30.50.2
Short access total locomotion0.10.20.50.4-0.60.40.4-0.40.7-0.6-0.6-0.6-0.40.4-0.40.6-0.60.4-0.20.0-0.10.3
One hour access (0.3 mA shock)1.11.32.1-1.21.4-1.3-1.31.3-1.21.31.30.51.1-1.11.3-1.41.4-1.3-0.1-0.90.4-0.6
Compulsive drug intake1.72.65.3-0.50.9-1.3-0.60.6-2.11.32.12.32.3-2.32.2-2.02.0-2.1-0.4-1.0-0.8-0.3
One hour access (shock baseline)0.20.63.3-0.1-0.00.4-0.10.20.9-0.3-0.9-1.8-1.01.0-0.80.5-0.50.80.6-0.11.1-0.4
Social response proportion0.30.41.50.5-0.40.50.4-0.40.5-0.3-0.4-0.9-0.10.10.0-0.00.0-0.00.9-1.21.2-0.9
Social responses0.10.20.40.2-0.30.30.4-0.40.5-0.5-0.5-0.2-0.70.7-0.40.3-0.30.4-0.2-0.10.30.1
Social time0.71.13.91.7-1.81.21.9-2.01.0-1.3-0.90.10.0-0.00.0-0.20.20.10.1-1.5-0.60.1
Soleus weight1.54.511.63.4-2.92.62.6-2.51.9-1.8-1.6-2.8-0.10.1-0.30.3-0.30.33.4-2.32.6-1.9
Bone: stiffness0.20.31.2-0.40.1-0.1-0.10.10.1-0.2-0.20.9-0.70.7-0.50.6-0.60.5-0.91.1-0.90.6
Tibialis anterior weight0.20.62.1-1.30.9-1.0-1.41.4-0.61.20.60.10.2-0.20.3-0.10.1-0.4-0.21.1-0.00.0
Time to tail flick, vehicle, before self-admin0.50.62.6-0.10.2-0.50.1-0.2-1.00.21.01.61.0-1.00.8-0.70.7-0.8-0.9-0.7-1.10.5
Time to tail flick, vehicle, after self-admin0.20.43.1-0.00.1-0.30.1-0.1-0.70.10.71.80.5-0.50.7-0.90.9-0.7-0.3-0.1-0.70.1
Time to tail flick, test, before self-admin0.10.10.6-0.30.4-0.2-0.10.0-0.2-0.10.10.8-0.30.3-0.1-0.10.10.1-0.50.1-0.50.2
Time to tail flick, test, after self-admin0.10.10.60.2-0.50.00.3-0.40.0-0.6-0.00.4-0.20.20.2-0.40.4-0.2-0.4-0.7-0.40.2
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.40.4-0.3-0.60.6-0.00.40.00.0-0.20.20.1-0.30.3-0.10.30.70.2-0.2
Delta time to tail flick, test, before/after SA0.30.30.6-0.70.3-0.8-0.70.6-0.60.60.60.50.7-0.70.7-0.50.5-0.7-0.4-0.2-0.20.0
Tibia length2.56.912.73.5-3.53.43.6-3.63.0-3.4-3.0-2.2-2.22.2-2.52.4-2.42.50.90.10.20.8
Ambulatory time before self-admin0.10.21.20.4-0.70.40.5-0.50.6-0.5-0.5-0.6-0.20.20.00.0-0.00.00.4-1.10.5-0.5
Ambulatory time after self-admin0.50.82.41.0-1.61.01.2-1.31.1-1.0-1.1-0.1-0.80.8-0.80.9-0.90.8-0.3-0.1-0.60.6
Bone: tissue strength0.50.51.30.3-0.50.60.5-0.50.9-0.7-0.9-0.3-1.11.1-0.90.7-0.70.9-0.20.8-0.20.3
Total heroin consumption0.10.10.90.2-0.30.10.2-0.20.2-0.2-0.2-0.1-0.10.10.2-0.60.6-0.20.2-0.90.1-0.3
Bone: trabecular number1.01.84.0-1.71.5-1.7-2.02.0-1.41.91.40.81.2-1.21.4-1.11.1-1.40.2-0.20.6-0.9
Bone: trabecular spacing2.84.06.52.0-2.12.32.4-2.42.3-2.6-2.4-1.4-2.22.2-2.32.1-2.12.3-0.20.9-0.61.3
Bone: trabecular thickness1.31.93.0-1.41.6-1.5-1.71.7-1.51.71.60.61.4-1.41.5-1.41.4-1.50.4-0.70.9-1.1
Bone: trabecular tissue density0.61.01.90.6-0.61.00.7-0.71.1-1.1-1.1-1.2-1.21.2-1.31.4-1.41.30.20.80.20.2
Water consumed over 24 hours0.10.10.30.4-0.50.30.5-0.50.4-0.4-0.40.1-0.20.2-0.20.2-0.20.2-0.4-0.0-0.50.5
Number of responses in last shaping day0.50.72.30.8-0.91.00.4-0.30.7-0.5-0.7-1.2-0.30.3-0.70.9-0.90.61.50.01.5-0.3