Hub : Genes

Trim15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Trim15 0.07 0.04 8.5e-06 0.04 0.06 0.04 0.06 5.6e-05 3.4e-06 8.9e-05 5.8e-06
2 Brain mRNA stability Trim15 0.06 0.04 3.3e-05 0.01 0.04 0.04 0.04 1.3e-02 1.5e-04 1.2e-04 2.3e-04
3 PL mRNA stability Trim15 0.03 0.02 6.4e-04 0 0.03 0.02 0.02 1.1e-01 8.1e-04 1.1e-03 7.0e-03
4 Brain alternative polyA XM_008772685.4 0.06 0.04 1.6e-05 0.03 0.05 0.04 0.04 6.8e-04 2.9e-05 2.1e-04 1.1e-04
5 Brain alternative polyA NM_001291382.2 0.08 0.04 5.1e-06 0.03 0.05 0.04 0.04 4.0e-04 2.9e-05 1.5e-04 8.9e-05
6 PL gene expression Trim15 0.08 0.05 4.6e-09 0.04 0.07 0.07 0.07 1.0e-04 2.2e-08 1.4e-08 3.1e-08
7 pVTA alternative polyA NM_001291382.2 0.17 0.09 1.4e-11 0.12 0.12 0.15 0.14 5.5e-10 1.1e-09 2.4e-12 1.2e-11
8 pVTA alternative polyA XM_008772685.4 0.16 0.09 2.4e-11 0.12 0.12 0.15 0.14 6.9e-10 6.8e-10 8.5e-12 2.2e-11
9 BLA gene expression Trim15 0.06 0.04 5.8e-03 0.03 0.02 0.02 0.02 8.1e-03 2.4e-02 3.8e-02 4.4e-02
10 NAcc alternative polyA NM_001291382.2 0.09 0.05 4.1e-15 0.1 0.1 0.1 0.1 3.2e-15 1.5e-15 1.9e-15 1.5e-15
11 Adipose alternative TSS NM_001291382.2 0.05 0.03 5.7e-07 0.06 0.06 0.06 0.06 1.9e-07 4.3e-07 1.0e-06 3.8e-07
12 Adipose alternative TSS XM_008772685.4 0.05 0.03 7.8e-07 0.06 0.06 0.05 0.06 2.7e-07 5.8e-07 1.4e-06 4.5e-07
13 PL alternative polyA NM_001291382.2 0.06 0.04 1.4e-07 0.06 0.06 0.05 0.06 2.1e-07 2.6e-07 1.5e-06 6.3e-07
14 PL alternative polyA XM_008772685.4 0.06 0.04 6.9e-08 0.06 0.06 0.06 0.06 1.6e-07 2.0e-07 1.0e-06 4.8e-07
15 NAcc alternative polyA XM_008772685.4 0.1 0.05 2.0e-15 0.1 0.11 0.11 0.11 1.4e-15 4.9e-16 7.3e-16 5.1e-16
16 Eye gene expression Trim15 0.4 0.19 5.0e-03 0.15 0.11 0.16 0.09 2.6e-03 1.1e-02 2.3e-03 1.5e-02
17 pVTA intron excision ratio chr20_1711734_1712151 0.06 0.05 9.5e-03 0.02 0.02 0.01 0.01 1.6e-02 1.1e-02 1.9e-02 2.6e-02
18 pVTA intron excision ratio chr20_1710062_1711619 0.08 0.05 5.6e-03 0.03 0.03 0.03 0.03 3.2e-03 3.9e-03 1.6e-03 3.2e-03
19 OFC alternative polyA NM_001291382.2 0.14 0.09 5.6e-03 0.1 0.05 0.05 0.08 2.2e-03 2.6e-02 2.6e-02 7.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.42.44.4-1.7-1.6-1.7-2.12.1-2.01.5-1.6-0.71.7-1.51.51.4-1.4-1.80.80.7-1.21.5
Area under the delay curve1.61.93.30.91.21.31.0-1.01.3-1.61.61.7-1.71.7-1.7-1.81.81.7-1.1-0.10.2-0.7
BMI with tail1.03.311.3-0.80.2-0.10.1-0.20.8-0.60.8-1.5-2.01.7-1.7-2.12.11.7-3.4-2.92.9-2.8
BMI without tail1.75.211.20.51.31.31.3-1.31.9-2.02.10.2-2.93.1-3.1-3.03.02.8-3.3-1.92.0-2.6
Body weight4.720.430.83.84.84.74.6-4.65.3-5.25.32.5-5.55.3-5.3-5.45.45.3-3.4-0.51.3-2.8
Weight adjusted by age2.13.25.92.01.72.21.9-1.82.3-2.22.12.4-2.11.7-1.7-1.61.61.80.11.3-1.20.5
Bone surface0.61.14.31.11.01.00.6-0.50.6-1.00.91.7-0.20.4-0.4-0.50.50.21.02.1-2.11.4
Bone volume0.30.53.10.20.10.3-0.20.3-0.1-0.40.31.10.00.2-0.2-0.30.3-0.00.61.5-1.81.3
Breakpoint value in progressive ratio session1.01.24.6-0.9-0.8-1.1-0.50.4-0.50.9-0.8-2.10.5-0.50.51.2-1.2-0.7-0.4-1.82.0-1.1
Number of licking bursts0.20.31.01.00.80.70.9-0.90.5-0.40.40.7-0.1-0.20.2-0.30.30.20.90.3-0.1-0.1
Context. condit. distance diff. score2.93.58.10.5-0.6-0.5-0.30.3-1.11.5-1.60.02.4-2.72.72.3-2.3-2.32.92.2-2.02.5
Locomotion velocity, session 10.20.20.80.70.50.30.3-0.30.0-0.20.20.40.4-0.20.20.4-0.4-0.30.90.9-0.70.6
Locomotion distance, session 11.11.32.2-1.5-1.4-1.5-1.51.5-1.51.3-1.3-1.31.1-1.01.01.1-1.1-1.1-0.3-0.50.40.3
Locomotion velocity, session 20.30.32.00.50.60.20.6-0.70.4-0.20.2-0.7-0.10.2-0.20.0-0.00.3-0.5-0.91.4-1.1
Locomotion distance, session 20.60.81.3-0.8-0.8-1.0-1.01.0-1.10.9-0.9-0.81.1-1.01.01.1-1.1-1.10.60.3-0.50.9
Locomotion velocity, session 30.60.73.1-0.8-0.6-0.7-0.40.4-0.40.6-0.5-1.3-0.0-0.10.1-0.20.20.1-1.2-1.71.8-1.3
Locomotion distance, session 31.31.52.4-1.1-1.2-1.3-1.21.2-1.41.5-1.5-1.01.4-1.51.51.4-1.4-1.40.6-0.1-0.00.5
Stereotopy head waving bouts, day 31.41.63.21.71.81.61.8-1.81.6-1.41.40.8-1.11.0-1.0-1.31.31.2-0.10.20.5-0.6
Stereotopy head waving duration, day 31.11.32.11.41.41.41.5-1.51.4-1.31.30.7-1.11.1-1.1-1.31.31.2-0.40.10.4-0.6
Locomotion velocity, session 73.13.46.1-0.8-1.5-1.3-1.51.6-1.92.0-2.0-0.02.2-2.52.52.1-2.1-2.11.61.6-1.92.0
Locomotion distance, session 72.93.65.7-1.5-2.1-1.8-2.02.0-2.12.3-2.3-0.72.1-2.42.42.0-2.0-2.11.00.9-1.51.8
Stereotopy head waving bouts, day 71.92.23.31.51.61.71.5-1.41.5-1.71.71.6-1.61.6-1.6-1.81.81.7-0.60.40.1-0.7
Stereotopy head waving duration, day 72.12.53.61.61.71.81.6-1.61.7-1.91.91.6-1.71.8-1.8-1.91.91.8-0.60.30.2-0.9
Locomotion velocity, session 81.92.36.62.62.12.02.1-2.01.5-1.41.31.6-0.30.2-0.2-0.30.30.41.72.1-1.41.1
Locomotion distance, session 81.92.86.30.1-0.6-0.6-0.50.6-1.01.3-1.4-0.22.0-2.32.32.0-2.0-2.12.51.9-2.02.5
Degree of sensitization distance0.40.41.80.70.30.60.4-0.40.3-0.20.11.00.0-0.20.2-0.00.0-0.00.81.3-1.30.9
Degree of sensitization stereotypy0.60.71.10.80.80.90.7-0.70.7-0.90.91.0-0.90.9-0.9-1.11.11.0-0.40.30.0-0.5
Conditioned locomotion1.92.23.61.21.31.31.5-1.61.6-1.51.50.5-1.71.7-1.7-1.71.71.8-1.2-1.01.5-1.9
Cocaine response after cond. corrected0.50.62.0-0.6-0.6-0.7-0.50.4-0.70.7-0.6-1.30.5-0.40.40.6-0.6-0.4-0.8-1.11.4-0.9
Cocaine response after cond. not corrected0.50.61.11.01.00.91.0-1.10.9-0.80.80.3-0.60.8-0.8-0.60.60.8-0.4-0.10.6-0.8
Cocaine response before conditioning6.17.312.83.13.03.32.9-2.83.1-3.23.23.6-2.72.7-2.7-2.82.82.70.22.0-1.60.2
Saline control response0.60.82.1-0.20.10.3-0.00.00.5-0.91.00.9-1.31.4-1.4-1.41.41.2-0.9-0.50.2-0.7
Bone: connectivity density2.03.14.9-1.2-1.3-1.5-1.81.9-2.11.6-1.6-0.32.2-2.02.01.8-1.8-2.21.71.5-2.02.2
Bone: cortical apparent density0.40.62.1-0.9-0.6-0.5-0.60.5-0.20.00.1-0.6-0.70.6-0.6-0.60.60.5-1.5-1.31.2-1.0
Bone: cortical area1.01.52.51.11.31.41.1-1.11.5-1.61.61.3-1.41.4-1.4-1.21.21.20.30.9-1.00.3
Bone: cortical porosity0.10.10.20.10.20.20.1-0.10.2-0.30.30.4-0.40.4-0.4-0.30.30.4-0.00.1-0.1-0.0
Bone: cortical porosity0.40.51.50.70.70.80.6-0.60.7-0.80.81.2-0.60.6-0.6-0.30.30.50.60.9-0.90.5
Bone: cortical thickness0.71.23.4-0.9-0.2-0.1-0.30.30.4-0.70.8-0.3-1.51.7-1.7-1.31.31.2-1.8-1.31.0-1.1
Bone: cortical thickness1.01.23.6-1.7-1.4-1.2-1.21.1-0.60.7-0.6-1.2-0.50.5-0.5-0.50.50.2-1.7-1.91.5-1.2
Bone: cortical tissue density0.40.51.9-0.9-0.5-0.5-0.50.5-0.2-0.00.1-0.6-0.70.5-0.5-0.60.60.5-1.4-1.31.1-1.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.1-0.1-0.2-0.20.2-0.30.2-0.2-0.30.3-0.30.30.4-0.4-0.30.00.10.10.1
Condit. Reinf. active-inactive response ratio0.40.52.1-0.20.2-0.00.1-0.10.1-0.30.3-0.6-0.50.6-0.6-0.50.50.6-1.3-1.11.4-1.2
Condit. Reinf. active responses0.50.60.9-0.7-0.9-0.9-0.70.7-0.90.9-0.9-0.90.8-1.01.01.0-1.0-0.90.2-0.20.10.3
Condit. Reinf. inactive responses2.53.04.8-1.9-2.2-2.0-1.91.9-1.92.1-2.0-1.61.6-1.91.91.9-1.9-1.90.7-0.2-0.41.1
Incentive salience index mean0.20.30.80.40.2-0.10.2-0.3-0.20.3-0.3-0.60.7-0.90.90.9-0.9-0.70.80.20.10.3
Condit. Reinf. lever presses1.11.63.90.3-0.1-0.50.1-0.2-0.61.0-1.1-1.41.7-2.02.01.9-1.9-1.71.90.3-0.10.7
Condit. Reinf. active minus inactive responses0.91.22.11.21.01.41.1-1.11.2-1.31.31.5-1.11.2-1.2-1.01.01.10.20.8-0.60.0
Condit. Reinf. active-inactive response ratio2.02.33.51.81.71.91.8-1.81.8-1.81.81.4-1.51.6-1.6-1.61.61.7-0.30.50.1-0.7
Condit. Reinf. active responses0.20.21.00.3-0.10.20.00.0-0.0-0.10.00.60.3-0.20.20.3-0.3-0.20.91.0-1.00.9
Condit. Reinf. inactive responses0.81.11.7-0.9-1.1-1.0-1.01.0-1.01.0-1.0-0.51.1-1.11.11.3-1.3-1.30.90.4-0.81.1
Condit. Reinf. lever presses1.42.05.4-0.4-1.0-0.7-0.91.0-1.00.9-1.00.51.5-1.51.51.6-1.6-1.52.31.7-2.22.1
Condit. Reinf. lever reinforcers received0.30.41.40.2-0.10.1-0.00.1-0.10.1-0.10.50.5-0.40.40.6-0.6-0.51.11.1-1.21.1
Conditioned reinforcement - actives0.30.52.0-0.2-0.20.3-0.10.10.5-0.80.81.4-1.11.1-1.1-0.90.90.9-0.70.1-0.5-0.1
Conditioned reinforcement - inactives0.20.31.6-0.5-0.4-0.1-0.40.40.3-0.40.51.3-0.90.8-0.8-0.50.50.6-0.2-0.2-0.4-0.2
Conditioned locomotion0.30.41.80.40.50.60.4-0.40.6-0.90.81.3-0.60.6-0.6-0.60.60.60.20.4-0.6-0.4
Patch foraging indifference point 0 sec0.50.93.7-0.9-1.2-0.6-1.31.4-1.00.5-0.51.00.5-0.40.40.1-0.1-0.4-0.11.4-1.91.5
Patch foraging indifference point AUC1.21.83.31.01.11.41.2-1.11.5-1.61.61.4-1.81.8-1.8-1.41.41.5-0.20.5-0.6-0.2
Delay disc. indifference point, 0s delay1.01.11.71.11.21.11.3-1.31.1-1.21.20.5-1.01.2-1.2-1.11.11.2-0.6-0.41.0-1.0
Delay disc. indifference point, 16s delay0.70.82.5-0.8-0.3-0.2-0.50.60.1-0.40.50.6-1.11.3-1.3-1.21.21.0-1.6-0.90.5-0.7
Delay disc. indifference point, 2s delay2.02.23.21.41.41.61.6-1.61.7-1.51.61.6-1.71.7-1.7-1.61.61.8-0.8-0.20.7-1.1
Delay disc. indifference point, 24s delay0.40.41.00.20.40.50.1-0.00.3-0.80.81.0-0.80.8-0.8-1.01.00.8-0.80.4-0.4-0.0
Delay disc. indifference point, 4s delay3.63.85.51.82.02.12.1-2.12.2-2.32.31.8-2.22.3-2.3-2.22.22.3-1.0-0.10.6-1.2
Delay disc. indifference point, 8s delay0.40.52.50.30.40.60.2-0.20.3-0.90.91.6-0.70.4-0.4-0.80.80.6-0.10.7-1.00.5
Indifference point function ln k0.30.51.40.40.10.10.1-0.1-0.10.3-0.40.40.8-1.01.00.8-0.8-0.71.21.0-0.81.0
Indifference point function log k0.30.51.40.40.10.10.1-0.1-0.10.3-0.40.40.8-1.01.00.8-0.8-0.71.21.0-0.81.0
Patch foraging total patch changes 0 sec0.50.94.0-1.0-1.2-0.6-1.41.5-1.00.4-0.41.20.3-0.20.2-0.10.1-0.3-0.11.4-2.01.5
Patch foraging total patch changes 12 sec0.30.41.3-1.0-0.9-0.4-1.01.0-0.40.00.00.5-0.50.7-0.7-0.20.20.2-0.50.5-1.10.8
Patch foraging total patch changes 18 sec1.11.64.3-2.0-1.9-1.7-2.02.1-1.71.6-1.5-0.90.8-0.70.70.4-0.4-0.9-0.8-0.3-0.30.4
Patch foraging total patch changes 24 sec1.22.16.7-2.2-2.1-1.8-2.52.6-2.01.2-1.20.10.8-0.60.60.7-0.7-1.0-0.20.5-1.51.2
Patch foraging total patch changes 6 sec0.40.62.6-1.1-0.9-0.4-1.11.2-0.5-0.00.10.7-0.60.8-0.8-0.70.70.5-1.60.3-0.80.4
Patch foraging time to switch 0 sec1.02.06.1-1.5-1.1-1.5-1.11.0-1.11.3-1.2-2.30.6-0.50.50.3-0.3-0.4-1.9-2.52.4-1.8
Patch foraging water rate 0 sec0.71.47.00.40.00.7-0.00.20.4-0.70.72.3-0.60.6-0.6-0.40.40.30.92.4-2.62.0
Patch foraging water rate 12 sec0.10.20.6-0.7-0.6-0.6-0.80.8-0.60.3-0.30.10.1-0.10.10.4-0.4-0.30.20.1-0.50.4
Patch foraging water rate 18 sec0.10.20.90.3-0.10.40.2-0.10.2-0.30.31.0-0.20.1-0.10.1-0.10.20.40.7-0.90.6
Patch foraging water rate 24 sec0.20.30.60.20.30.50.3-0.30.5-0.40.50.5-0.60.8-0.8-0.70.70.7-0.5-0.0-0.3-0.1
Patch foraging water rate 6 sec0.20.30.8-0.9-0.7-0.7-0.80.9-0.60.3-0.30.20.20.0-0.00.6-0.6-0.40.1-0.2-0.30.1
Seeking ratio, delayed vs. immediate footshock0.50.61.80.70.70.70.8-0.90.8-0.70.8-0.1-0.70.8-0.8-0.60.60.8-0.3-0.50.8-1.3
Distance traveled before self-admin0.50.62.50.91.00.80.9-0.90.7-0.80.71.0-0.20.2-0.2-0.00.00.01.60.9-0.90.9
Distance traveled after self-admin0.80.92.71.21.71.11.3-1.31.1-1.21.10.4-0.90.7-0.7-0.90.90.80.40.20.1-0.3
Extensor digitorum longus weight0.62.310.91.41.01.10.5-0.40.3-0.70.62.60.3-0.30.30.1-0.1-0.21.93.3-3.32.5
Bone: elastic displacement0.20.30.9-0.20.2-0.0-0.10.1-0.1-0.40.40.2-0.40.6-0.6-0.60.60.5-0.9-0.60.7-0.9
Bone: elastic work0.81.12.20.31.00.60.6-0.70.8-1.21.20.4-1.11.5-1.5-1.31.31.1-1.3-0.80.9-1.2
Bone: endosteal estimation3.98.618.34.34.04.03.9-3.93.5-3.43.33.2-2.11.9-1.9-2.32.32.31.12.5-1.50.4
Bone: endosteal perimeter1.83.89.63.02.42.32.3-2.21.8-1.61.42.4-0.1-0.10.1-0.10.10.22.83.1-2.71.8
Epididymis fat weight2.79.226.8-5.0-3.5-3.4-3.83.7-2.51.8-1.5-3.2-0.91.2-1.2-1.01.00.5-5.2-4.83.5-2.9
Delta time in closed arm before/after self-admin0.20.10.40.10.20.30.1-0.10.3-0.30.30.2-0.70.6-0.6-0.50.50.6-0.40.1-0.1-0.2
Delta time in open arm before/after self-admin0.60.62.70.40.70.50.3-0.30.4-0.80.81.6-0.60.4-0.4-0.40.40.31.11.0-1.41.0
Diff in mean of infusions in LGA sessions3.03.75.5-1.8-1.9-2.2-1.81.8-2.12.3-2.4-1.92.2-2.22.22.4-2.4-2.20.9-1.10.80.1
Delay discount exponential model param1.71.93.3-0.9-1.2-1.3-1.11.0-1.31.7-1.7-1.81.7-1.71.71.8-1.8-1.71.00.1-0.20.8
Extinction: sum of active levers before priming1.51.64.2-1.3-1.2-1.5-1.00.9-1.01.4-1.3-2.01.0-1.11.11.4-1.4-1.2-0.1-1.61.5-0.7
Active lever presses in extinction session 61.71.77.2-1.7-1.1-1.5-1.00.9-0.70.7-0.6-1.90.10.2-0.20.6-0.6-0.2-1.3-2.72.6-1.7
Bone: final force1.42.25.00.31.01.00.8-0.81.4-1.51.60.3-2.12.2-2.2-2.12.11.9-1.7-0.80.7-1.1
Bone: final moment1.11.74.10.50.91.10.8-0.71.3-1.41.50.8-1.92.0-2.0-1.81.81.7-1.1-0.1-0.0-0.4
Food consumed during 24 hour testing period0.91.22.81.61.61.41.6-1.71.4-1.31.30.7-0.80.9-0.9-0.90.91.0-0.10.00.4-0.7
Glucose2.53.913.32.61.71.61.6-1.50.7-0.50.32.41.3-1.51.51.1-1.1-1.03.63.7-3.12.4
Heart weight2.03.15.61.41.51.91.3-1.21.8-2.12.12.0-2.32.1-2.1-2.42.42.1-1.31.0-0.7-0.3
Delay discount hyperbolic model param1.71.93.3-0.9-1.1-1.3-1.11.1-1.31.6-1.6-1.71.7-1.71.71.8-1.8-1.81.10.2-0.40.9
Intermittent access intake day 1-15 change0.00.00.30.0-0.10.10.2-0.20.1-0.10.10.3-0.3-0.00.00.2-0.20.10.2-0.30.1-0.5
Intermittent access intake escalation0.10.31.3-0.10.00.10.3-0.30.4-0.30.30.1-0.80.5-0.5-0.40.40.6-0.6-0.90.8-1.1
Intermittent access intake escalation 20.50.61.71.00.70.90.9-0.90.8-0.70.61.3-0.60.0-0.0-0.00.00.21.01.1-1.10.6
Intermitt. access day 1 inactive lever presses0.10.51.41.21.20.91.2-1.20.9-0.80.70.8-0.10.0-0.0-0.10.10.21.00.4-0.1-0.2
Intermitt. access day 15 inactive lever presses0.50.93.81.31.31.21.1-1.10.9-1.01.01.9-0.40.3-0.3-0.80.80.70.51.0-0.80.0
Intermitt. access escalation Index1.31.96.7-1.0-1.0-1.4-0.80.7-1.11.4-1.4-2.61.5-1.41.41.6-1.6-1.50.3-1.31.5-0.9
Intermittent access day 1 total infusions0.30.51.7-1.3-1.0-1.0-1.11.1-0.80.5-0.5-0.50.2-0.00.00.2-0.2-0.2-0.4-0.80.30.0
Intermittent access day 15 total infusions0.40.62.5-0.8-0.4-0.3-0.30.3-0.0-0.20.3-0.3-0.90.9-0.9-0.50.50.7-1.2-1.61.3-1.2
Intermittent access terminal intake (last 3 days)0.30.40.8-0.7-0.4-0.2-0.40.4-0.1-0.30.40.6-0.90.8-0.8-0.70.70.8-0.9-0.80.4-0.6
Intermittent access total infusions0.20.30.6-0.6-0.3-0.2-0.30.4-0.1-0.40.40.5-0.80.7-0.7-0.60.60.6-0.7-0.70.3-0.4
Intermittent access day 1 locomotion0.30.31.1-0.10.30.10.3-0.30.3-0.40.5-0.1-0.40.6-0.6-0.60.60.6-0.5-1.01.0-1.0
Intermittent access day 15 total locomotion1.83.24.71.31.61.71.8-1.82.0-2.12.10.9-2.12.1-2.1-2.12.12.2-1.2-0.91.1-1.6
Intermittent access total locomotion2.12.63.91.11.41.51.6-1.61.7-1.81.90.9-2.01.9-1.9-1.91.92.0-1.0-0.91.0-1.5
Intermittent access standard deviation0.61.35.20.20.10.80.3-0.21.0-1.31.32.3-1.81.4-1.4-1.01.01.2-0.20.7-1.30.5
Left kidney weight2.511.818.12.93.63.73.2-3.13.8-4.14.13.0-4.14.3-4.3-4.24.24.1-2.00.6-0.2-1.4
Right kidney weight3.616.424.03.54.24.43.9-3.94.6-4.94.93.6-4.94.8-4.8-4.94.94.8-2.40.7-0.1-1.7
Cocaine induced anxiety0.50.72.51.10.70.60.8-0.80.3-0.10.00.70.8-0.80.80.8-0.8-0.51.61.2-1.00.8
Post-drug Anxiety0.40.42.00.40.20.00.3-0.40.00.4-0.40.10.6-0.90.91.0-1.0-0.71.40.3-0.20.8
Baseline Anxiety1.61.94.7-1.9-1.7-1.8-1.71.6-1.31.7-1.6-2.20.5-0.80.81.0-1.0-0.9-0.6-1.61.3-0.5
Tail length4.617.928.95.25.35.45.1-5.05.1-5.25.24.4-4.04.1-4.1-3.83.84.1-0.02.5-1.6-0.3
Length with tail6.427.845.56.46.46.76.2-6.06.3-6.56.45.9-5.05.0-5.0-4.74.75.00.13.9-2.90.5
Length without tail4.514.521.94.34.74.74.4-4.44.7-4.74.63.3-4.23.9-3.9-3.83.84.1-1.11.3-0.5-0.9
Times rat made contact with spout2.22.54.4-2.1-1.9-2.1-2.02.0-2.01.9-1.9-1.71.5-1.41.41.5-1.5-1.5-0.2-1.10.6-0.1
Lifetime Intake0.30.40.9-0.4-0.00.1-0.10.20.2-0.60.70.6-1.01.0-1.0-0.80.80.8-0.8-0.60.2-0.3
Liver weight, left2.03.48.32.92.92.52.8-2.82.4-2.12.01.3-1.00.9-0.9-1.01.01.11.01.4-0.70.3
Liver weight, right4.37.515.63.74.03.63.7-3.73.5-3.33.22.4-2.32.0-2.0-2.52.52.5-0.21.2-0.3-0.7
Locomotor activity2.54.08.62.82.42.52.3-2.32.0-1.91.82.9-0.80.7-0.7-1.01.00.92.12.8-2.51.5
Locomotor testing distance1.01.86.31.61.31.31.0-0.90.6-0.70.62.40.3-0.30.3-0.20.2-0.11.92.5-2.51.7
Locomotor testing rearing0.61.32.61.61.51.51.4-1.41.2-1.11.11.4-0.40.6-0.6-0.90.90.61.01.4-1.20.8
Locomotion in novel chamber0.20.20.60.30.40.50.3-0.30.5-0.70.60.5-0.70.8-0.8-0.10.10.4-0.00.5-0.50.5
Locomotion in novel chamber post-restriction0.30.61.30.50.80.70.6-0.50.8-0.80.80.7-0.81.1-1.1-0.90.91.0-0.50.00.1-0.3
Fecal boli incidents, locomotor time 10.60.91.9-0.6-0.8-0.8-0.90.9-1.20.9-1.00.01.4-1.11.11.2-1.2-1.10.90.6-0.70.9
Change in fecal boli incidents, locomotor task1.71.62.51.01.11.11.3-1.41.5-1.21.20.4-1.51.3-1.3-1.41.41.4-1.3-1.01.5-1.6
Time >=10cm from walls, locomotor time 11.11.22.91.51.71.31.6-1.61.3-1.21.20.9-0.80.8-0.8-1.01.01.0-0.10.00.3-0.6
Bouts of movement, locomotor time 11.01.14.90.40.00.2-0.10.1-0.20.0-0.11.30.6-0.90.90.7-0.7-0.71.81.9-2.21.9
Total resting periods, locomotor time 10.50.52.30.70.30.50.3-0.30.2-0.30.21.00.3-0.40.40.2-0.2-0.21.21.4-1.51.2
Rest time, locomotor task time 10.91.12.71.51.41.41.6-1.61.4-1.21.20.5-0.90.8-0.8-0.70.71.00.00.00.4-0.5
Distance moved, locomotor task time 10.10.21.0-0.4-0.4-0.2-0.60.7-0.30.2-0.20.30.10.1-0.1-0.10.1-0.1-0.20.8-1.00.7
Vertical activity count, locomotor time 10.10.21.2-0.4-0.4-0.2-0.60.6-0.20.2-0.20.70.2-0.00.00.2-0.2-0.30.30.7-1.10.8
Time >=10cm from walls, locomotor time 20.60.91.81.21.41.11.0-1.01.0-1.21.11.3-0.90.7-0.7-0.80.80.80.20.9-0.70.3
Bouts of movement, locomotor time 21.32.04.11.82.01.71.8-1.81.7-2.02.01.1-1.21.3-1.3-0.90.91.10.60.9-0.60.4
Total resting periods, locomotor time 21.22.14.32.02.11.81.9-1.91.7-1.91.91.0-1.11.1-1.1-0.70.70.91.01.2-0.90.6
Rest time, locomotor task time 20.81.13.82.01.51.41.9-1.91.3-0.70.70.10.1-0.20.20.2-0.20.11.40.8-0.20.4
Distance moved, locomotor task time 20.40.41.5-1.0-0.8-0.4-1.01.1-0.50.2-0.20.1-0.60.7-0.7-0.70.70.4-1.20.1-0.50.1
Vertical activity count, locomotor time 20.20.20.8-0.8-0.6-0.6-0.90.9-0.40.4-0.4-0.2-0.00.1-0.10.0-0.0-0.2-0.50.1-0.50.3
Light reinforcement 10.00.10.3-0.5-0.4-0.4-0.50.6-0.3-0.00.0-0.1-0.10.4-0.4-0.00.00.1-0.5-0.2-0.1-0.2
Light reinforcement 21.82.84.61.81.82.01.7-1.61.8-2.12.11.9-1.72.0-2.0-1.71.71.9-0.50.8-0.7-0.5
Bone: marrow area3.88.317.64.23.93.93.9-3.83.5-3.33.23.1-2.11.9-1.9-2.32.32.31.02.4-1.40.3
Bone: maximum diameter1.42.66.52.31.92.01.9-1.81.6-1.51.42.0-0.40.3-0.3-0.30.30.42.12.5-2.31.5
Bone: maximum force1.32.34.80.81.41.41.2-1.11.6-1.71.80.8-2.02.2-2.2-2.12.11.8-1.3-0.20.2-0.6
Bone: maximum moment1.22.13.91.01.41.51.1-1.11.6-1.81.81.4-1.82.0-2.0-1.81.81.6-0.70.6-0.60.1
Mean time between licks in bursts0.71.74.52.11.61.61.7-1.71.3-1.11.01.7-0.2-0.10.1-0.10.10.21.81.8-1.41.0
Mean num. licks in bursts0.91.43.6-1.9-1.6-1.6-1.71.7-1.41.2-1.2-1.40.8-0.40.41.0-1.0-0.9-0.9-0.80.30.1
Cd content in liver0.20.20.8-0.7-0.7-0.5-0.90.9-0.60.3-0.30.30.2-0.10.10.1-0.1-0.3-0.50.4-0.60.6
Co content in liver0.30.31.5-0.9-0.6-0.4-0.70.7-0.30.1-0.1-0.2-0.50.5-0.5-0.50.50.4-1.2-0.70.4-0.4
Cu content in liver1.92.35.7-2.4-2.0-2.1-2.32.3-1.91.6-1.5-1.41.2-0.90.91.1-1.1-1.40.0-0.8-0.10.4
Fe content in liver0.80.93.5-0.5-0.1-0.2-0.0-0.00.1-0.30.4-0.8-0.81.0-1.0-0.80.80.9-1.6-1.81.7-1.9
K content in liver0.80.81.3-1.0-1.0-1.1-1.11.1-1.11.1-1.1-0.81.0-1.01.00.7-0.7-1.00.2-0.3-0.10.2
Mg content in liver0.50.51.60.1-0.1-0.2-0.10.1-0.30.6-0.60.10.9-1.01.00.7-0.7-0.91.30.6-1.00.7
Mn content in liver1.21.35.71.30.60.50.8-0.80.00.3-0.40.51.3-1.41.41.1-1.1-1.12.41.6-1.41.2
Na content in liver0.30.31.1-1.0-0.7-0.7-0.80.8-0.60.5-0.4-0.5-0.10.1-0.1-0.20.2-0.0-0.6-0.90.3-0.6
Rb content in liver0.50.50.8-0.8-0.7-0.8-0.90.9-0.80.6-0.6-0.20.8-0.70.70.7-0.7-0.90.90.4-0.90.8
Se content in liver1.21.43.92.01.71.51.7-1.71.2-1.31.21.3-0.20.3-0.3-0.30.30.41.31.4-0.90.5
Sr content in liver0.80.71.40.81.00.91.1-1.11.2-1.01.00.2-0.90.8-0.8-0.60.60.8-0.0-0.30.5-0.7
Zn content in liver0.40.42.20.20.10.0-0.10.2-0.2-0.1-0.00.60.5-0.40.40.4-0.4-0.60.81.3-1.51.3
Bone: minimum diameter1.52.86.82.62.32.12.3-2.21.9-1.71.71.8-0.60.5-0.5-0.50.50.62.12.0-1.60.9
Time in familiar zone, hab. session 13.63.56.2-2.5-2.2-2.4-2.32.3-2.22.4-2.4-2.21.7-1.61.61.4-1.4-1.6-0.8-1.40.8-0.1
Time in novel zone, hab. session 13.93.910.52.42.02.41.8-1.71.9-2.32.23.2-1.41.3-1.3-1.11.11.21.62.8-2.51.5
Total zone transitions, hab. session 10.81.11.7-0.8-1.0-1.0-1.11.1-1.21.0-1.1-0.31.3-1.31.31.1-1.1-1.31.00.7-1.01.1
Total locomotion distance, hab. session 10.60.81.2-0.9-0.9-1.0-1.11.1-1.11.0-1.0-0.71.0-1.01.00.9-0.9-1.00.40.0-0.30.6
Locomotion velocity, hab. session 10.50.71.2-1.1-0.9-1.1-1.01.0-1.01.0-0.9-1.00.8-0.80.80.7-0.7-0.8-0.0-0.60.40.0
Time in familiar zone, hab. session 21.01.02.7-1.3-1.2-1.3-1.11.0-1.11.3-1.2-1.60.9-0.70.70.8-0.8-0.9-0.2-1.00.6-0.1
Time in novel zone, hab. session 20.91.03.21.10.91.20.8-0.70.9-1.21.21.8-1.00.8-0.8-0.80.81.00.11.1-0.80.2
Total zone transitions, hab. session 20.20.30.5-0.7-0.7-0.6-0.60.6-0.50.6-0.6-0.60.3-0.50.50.3-0.3-0.3-0.3-0.60.5-0.3
Total locomotion distance, hab. session 21.11.42.2-1.3-1.3-1.4-1.31.3-1.41.5-1.5-1.01.3-1.41.41.2-1.2-1.30.3-0.30.10.4
Locomotion velocity, hab. session 21.21.62.4-1.3-1.4-1.5-1.41.4-1.51.6-1.6-1.11.4-1.51.51.3-1.3-1.40.3-0.40.10.4
Novel to familiar place preference ratio0.10.10.4-0.1-0.00.1-0.20.3-0.0-0.20.30.6-0.40.3-0.3-0.30.30.3-0.50.3-0.20.0
Novelty place preference0.20.20.80.20.30.40.1-0.10.3-0.60.60.9-0.70.6-0.6-0.60.60.6-0.60.4-0.2-0.1
Time in novel zone, NPP test0.40.51.30.50.60.70.3-0.30.5-0.90.91.2-0.90.8-0.8-0.80.80.8-0.60.6-0.3-0.0
Total zone transitions, NPP test1.01.42.5-0.6-0.8-0.9-1.11.2-1.31.0-1.10.21.4-1.41.41.2-1.2-1.41.31.3-1.51.6
Total locomotion distance, NPP test1.01.32.4-1.2-1.3-1.3-1.51.5-1.61.3-1.3-0.41.3-1.31.31.1-1.1-1.30.40.3-0.60.9
Locomotion velocity, NPP test1.82.54.2-1.7-1.7-1.8-1.91.9-2.01.8-1.8-0.91.8-1.81.81.6-1.6-1.80.60.1-0.51.0
Intraocular pressure0.50.81.4-0.5-1.0-0.6-0.80.8-0.70.8-0.80.11.1-0.80.81.0-1.0-1.01.20.8-1.11.2
Delta distance traveled before/after self-admin1.11.22.70.61.10.90.8-0.70.8-1.01.00.3-1.31.1-1.1-1.61.61.4-1.5-0.50.8-1.2
Delta ambulatory time before/after self-admin0.80.91.80.81.10.90.9-0.90.8-0.80.8-0.0-1.11.0-1.0-1.41.41.2-1.3-0.40.8-1.1
Parametrial fat weight0.71.73.00.81.21.21.1-1.11.4-1.41.50.5-1.71.7-1.7-1.61.61.5-1.0-0.40.6-0.9
Pavlov. Cond. lever latency0.91.13.6-1.9-1.4-1.2-1.41.4-0.60.5-0.5-1.0-0.40.8-0.8-0.30.30.2-1.7-1.61.1-0.8
Pavlov. Cond. magazine entry latency0.60.82.61.00.50.20.8-0.90.00.4-0.4-0.61.1-1.41.41.2-1.2-1.01.60.40.20.3
Pavlov. Cond. change in total contacts1.41.54.22.01.71.71.8-1.81.4-1.31.31.2-0.80.5-0.5-0.80.81.00.20.8-0.2-0.3
Pavlov. Cond. index score0.70.92.81.61.00.71.3-1.30.4-0.0-0.1-0.20.9-1.21.20.8-0.8-0.71.70.7-0.00.3
Pavlov. Cond. latency score0.70.93.01.71.20.91.4-1.50.6-0.30.20.10.6-1.01.00.6-0.6-0.51.70.9-0.20.3
Pavlov. Cond. lever contacts0.91.13.71.91.41.31.5-1.50.8-0.60.61.00.3-0.60.60.2-0.2-0.11.51.4-0.90.6
Pavlov. Cond. magazine entry number0.81.02.9-0.5-0.20.3-0.40.50.4-0.80.81.1-1.41.7-1.7-1.41.41.2-1.30.1-0.6-0.0
Pavlov. Cond. intertrial magazine entries0.81.02.9-1.6-1.6-1.3-1.61.7-1.20.9-0.9-0.60.4-0.20.20.7-0.7-0.5-0.6-0.2-0.20.5
Pavlov. Cond. lever-magazine prob. diff.0.70.92.71.40.90.51.1-1.10.20.2-0.2-0.41.0-1.41.40.9-0.9-0.81.70.70.00.4
Pavlov. Cond. response bias0.70.82.01.30.80.51.0-1.10.20.2-0.3-0.41.0-1.41.41.0-1.0-0.81.40.60.10.2
Pavlov. Cond. lever latency0.60.81.50.81.00.81.0-1.00.9-0.70.8-0.2-0.80.9-0.9-0.90.90.9-1.0-0.71.2-1.2
Pavlov. Cond. magazine entry latency0.30.30.60.70.70.70.8-0.80.7-0.80.80.5-0.60.5-0.5-0.60.60.60.20.1-0.1-0.1
Pavlov. Cond. change in total contacts0.10.10.40.00.10.2-0.00.10.1-0.30.30.6-0.30.3-0.3-0.30.30.3-0.10.3-0.40.2
Pavlov. Cond. index score0.10.20.90.20.00.20.0-0.00.0-0.20.20.70.1-0.10.10.1-0.1-0.10.70.7-0.90.7
Pavlov. Cond. latency score0.00.10.30.0-0.00.1-0.00.00.0-0.20.20.4-0.0-0.00.00.0-0.0-0.00.50.4-0.60.4
Pavlov. Cond. lever contacts0.40.51.4-0.6-0.7-0.6-0.80.9-0.70.5-0.50.40.6-0.70.70.6-0.6-0.70.90.8-1.21.1
Pavlov. Cond. magazine entry number0.20.30.7-0.5-0.5-0.6-0.50.5-0.50.7-0.7-0.90.6-0.50.50.7-0.7-0.6-0.1-0.40.5-0.1
Pavlov. Cond. intertrial magazine entries0.30.41.70.70.20.20.5-0.50.10.3-0.3-0.10.7-0.80.80.9-0.9-0.61.30.7-0.40.6
Pavlov. Cond. lever-magazine prob. diff.0.20.21.10.20.00.2-0.00.1-0.1-0.10.10.70.2-0.20.20.1-0.1-0.20.80.9-1.10.8
Pavlov. Cond. response bias0.30.41.60.1-0.1-0.0-0.20.2-0.30.1-0.10.80.4-0.60.60.4-0.4-0.41.11.1-1.31.1
Time in closed arm before self-admin0.20.20.8-0.4-0.5-0.4-0.20.2-0.10.5-0.4-0.60.0-0.10.1-0.10.1-0.1-0.7-0.80.9-0.6
Time in closed arm after self-admin1.11.24.7-0.6-0.1-0.1-0.10.10.4-0.20.3-0.7-1.31.2-1.2-1.21.21.1-2.2-1.71.6-1.7
Time in open arm before self-admin0.20.21.10.2-0.3-0.10.1-0.10.10.4-0.4-1.00.6-0.40.40.8-0.8-0.50.30.20.30.1
Time in open arm after self-admin0.60.62.80.50.20.20.2-0.20.10.1-0.20.10.6-0.70.70.9-0.9-0.81.71.3-1.21.4
Bone: periosteal estimation3.06.310.63.33.23.33.1-3.03.1-3.13.02.8-2.22.1-2.1-2.22.22.10.72.1-1.50.5
Bone: periosteal perimeter1.62.85.52.32.22.22.1-2.02.0-1.91.81.9-1.11.0-1.0-1.11.11.01.41.9-1.60.9
Bone: post-yield work1.62.38.81.91.21.41.2-1.11.0-0.70.61.80.3-0.50.50.4-0.4-0.42.53.0-2.72.5
Progressive ratio test 1 active lever presses0.50.62.9-0.9-0.4-0.5-0.40.4-0.1-0.00.1-0.8-0.70.7-0.7-0.40.40.5-1.3-1.71.5-1.2
Progressive ratio test 1 breakpoint0.50.62.6-0.8-0.4-0.5-0.40.3-0.1-0.10.1-0.7-0.70.7-0.7-0.50.50.5-1.2-1.61.4-1.2
Progressive ratio test 1 inactive lever presses0.50.72.7-1.7-1.5-1.2-1.51.5-0.90.7-0.7-0.2-0.2-0.10.10.3-0.3-0.3-0.5-0.80.2-0.5
Progressive ratio test 2 active lever presses0.70.83.0-1.4-1.2-1.1-1.00.9-0.80.6-0.5-1.0-0.00.2-0.20.2-0.2-0.0-0.8-1.71.4-0.7
Progressive ratio test 2 breakpoint0.80.93.6-1.5-1.1-1.1-1.00.9-0.70.6-0.5-1.0-0.10.2-0.20.2-0.20.0-1.0-1.91.6-0.9
Progressive ratio test 2 inactive lever presses0.10.10.50.0-0.10.20.2-0.20.4-0.30.30.7-0.60.5-0.5-0.40.40.5-0.2-0.20.0-0.1
Incentive Sensitization - Responses0.60.91.6-1.3-1.3-1.3-1.01.0-1.01.0-1.0-1.00.7-0.60.61.0-1.0-0.7-0.1-1.31.0-0.2
Incentive Sensitization - Breakpoint0.70.91.8-1.3-1.3-1.3-1.11.0-1.01.0-1.0-1.10.7-0.60.61.0-1.0-0.7-0.1-1.31.1-0.2
Sum of active levers in priming session hrs 5-60.20.10.4-0.2-0.2-0.4-0.20.2-0.40.5-0.5-0.10.6-0.40.40.5-0.5-0.50.5-0.10.10.1
Progressive ratio2.74.38.80.81.31.41.5-1.61.9-1.61.8-0.4-2.72.5-2.5-2.32.32.6-2.5-2.12.5-3.0
Food seeking constrained by brief footshock0.00.10.3-0.0-0.2-0.0-0.20.2-0.0-0.00.0-0.10.10.2-0.20.2-0.2-0.10.00.5-0.30.5
Seeking ratio, punishment vs. effort2.33.48.1-0.7-1.1-1.2-1.51.5-1.71.3-1.40.52.3-1.91.92.0-2.0-2.32.22.1-2.42.8
Retroperitoneal fat weight0.41.83.91.01.21.41.2-1.11.5-1.61.71.0-2.01.6-1.6-1.61.61.7-1.00.2-0.1-0.6
Reaction time number correct0.30.62.9-1.0-1.1-0.6-0.90.9-0.50.5-0.5-0.3-0.40.4-0.4-0.40.40.4-1.7-0.80.6-0.7
Reaction time mean minus median1.12.77.02.62.52.12.3-2.31.8-1.51.31.6-0.30.1-0.1-0.00.00.32.32.0-1.41.1
Reaction time mean minus median AUC0.92.25.12.22.01.71.8-1.81.5-1.21.11.8-0.3-0.00.0-0.00.00.22.22.1-1.71.4
Reaction time num false alarms0.10.20.50.70.60.60.5-0.50.3-0.20.20.5-0.0-0.00.0-0.50.50.2-0.10.5-0.30.0
Reaction time num false alarms AUC0.10.20.80.90.60.70.6-0.60.4-0.30.20.7-0.1-0.00.0-0.40.40.20.10.8-0.50.2
Reaction time trials correct on left0.30.62.9-1.0-1.1-0.6-0.90.9-0.50.5-0.5-0.3-0.40.4-0.4-0.40.40.4-1.7-0.80.6-0.7
Reaction time trials on left0.30.52.7-0.9-1.0-0.5-0.80.8-0.40.5-0.4-0.3-0.40.5-0.5-0.50.50.4-1.6-0.80.6-0.7
Reaction time mean1.72.68.52.41.91.61.8-1.71.1-0.80.72.00.7-0.80.80.4-0.4-0.42.92.7-2.11.9
Reaction time mean AUC1.82.88.52.52.01.81.9-1.81.2-1.00.92.20.5-0.60.60.3-0.3-0.32.92.7-2.11.9
Median of all reaction times1.31.86.61.81.41.21.2-1.20.6-0.50.31.70.8-0.90.90.4-0.4-0.62.62.3-1.91.8
Reaction time omissions0.91.34.82.21.71.62.0-2.01.2-0.90.80.90.0-0.10.10.1-0.10.31.51.1-0.30.2
Reaction time false alarm rate0.50.72.01.41.11.01.0-1.00.7-0.60.51.00.2-0.30.3-0.10.1-0.01.21.4-1.00.8
Reaction time premature initiation rate0.50.61.20.60.80.70.7-0.70.8-1.01.00.6-0.91.1-1.1-0.80.81.0-0.7-0.20.3-0.7
Reaction time premature initiations0.50.93.10.10.20.40.2-0.20.5-0.70.70.4-1.21.3-1.3-1.21.21.3-1.8-0.70.9-1.2
Std. dev. reaction times1.83.38.62.92.62.32.5-2.51.9-1.71.62.1-0.30.1-0.1-0.20.20.42.52.4-1.61.4
Reaction time trials completed0.30.52.7-0.9-1.0-0.5-0.80.8-0.40.5-0.4-0.3-0.40.5-0.5-0.50.50.4-1.6-0.80.6-0.7
Reaction time trials AUC0.30.52.7-1.0-1.0-0.6-0.80.8-0.50.6-0.5-0.3-0.40.4-0.4-0.40.40.4-1.7-0.80.6-0.7
Run reversals in cocaine runway, females0.50.51.2-0.9-1.0-0.7-1.01.1-0.80.5-0.50.20.5-0.40.40.5-0.5-0.70.20.6-1.01.0
Run reversals in cocaine runway, males2.92.96.62.52.62.32.4-2.32.0-2.01.91.5-1.01.1-1.1-1.21.21.30.71.3-0.80.1
Latency to leave start box in cocaine runway0.10.10.60.0-0.4-0.10.1-0.2-0.00.3-0.3-0.10.0-0.20.2-0.00.00.1-0.4-0.60.8-0.5
Latency to leave start box in cocaine runway, F0.50.51.2-0.1-0.7-0.4-0.30.4-0.50.8-0.80.10.8-1.11.11.0-1.0-0.80.90.6-0.60.9
Latency to leave start box in cocaine runway, M1.81.73.90.40.50.70.9-1.01.1-0.90.90.0-1.41.3-1.3-1.61.61.5-1.9-1.72.0-1.9
Std. dev. time between licks in bursts1.21.74.92.21.71.71.9-1.91.5-1.21.21.3-0.40.2-0.2-0.20.20.41.61.6-1.00.8
Total sessions with >9 infusions0.30.40.9-0.40.1-0.0-0.10.10.2-0.50.60.1-0.80.8-0.8-0.90.90.7-0.9-0.90.7-0.7
Short access day 1 total inactive lever presses1.31.72.91.51.71.61.6-1.61.7-1.71.71.4-1.21.3-1.3-1.11.11.30.50.6-0.4-0.1
Short access day 10 total inactive lever presses0.51.22.9-0.4-0.7-0.8-0.50.5-0.81.1-1.1-0.51.4-1.61.61.7-1.7-1.51.70.3-0.50.4
Short access day 1 total infusions0.10.10.7-0.4-0.2-0.2-0.50.5-0.30.1-0.10.20.0-0.00.0-0.00.0-0.10.20.4-0.70.8
Short access day 10 total infusions0.20.20.6-0.4-0.1-0.1-0.30.30.0-0.30.30.3-0.60.5-0.5-0.70.70.5-0.7-0.50.30.1
Short access total infusions0.20.30.7-0.40.00.0-0.30.30.1-0.50.50.5-0.80.8-0.8-0.80.80.7-0.7-0.3-0.10.1
Short access day 1 locomotion0.60.81.4-0.8-0.9-0.9-1.01.1-1.00.8-0.9-0.40.8-1.21.20.7-0.7-1.00.40.3-0.61.1
Short access day 10 total locomotion0.61.22.11.41.51.41.4-1.41.4-1.41.41.3-0.90.9-0.9-0.80.80.90.40.7-0.5-0.2
Short access total locomotion0.20.20.50.40.60.40.4-0.40.6-0.70.60.6-0.60.4-0.4-0.60.60.4-0.0-0.20.1-0.3
One hour access (0.3 mA shock)1.11.32.1-1.2-1.4-1.3-1.31.3-1.31.2-1.3-0.51.2-1.11.11.4-1.4-1.30.8-0.1-0.40.6
Compulsive drug intake2.22.76.6-0.5-0.9-1.3-0.60.6-1.32.1-2.1-2.32.6-2.32.32.0-2.0-2.11.0-0.40.80.3
One hour access (shock baseline)0.40.63.3-0.10.00.4-0.10.20.3-0.90.91.8-1.11.0-1.0-0.50.50.80.20.6-1.10.4
Social response proportion0.30.41.60.50.40.50.4-0.40.3-0.50.40.9-0.00.1-0.10.0-0.0-0.01.30.9-1.20.9
Social responses0.10.20.40.20.30.30.4-0.40.5-0.50.50.2-0.60.7-0.7-0.30.30.40.1-0.2-0.3-0.1
Social time0.81.13.91.71.81.21.9-2.01.3-1.00.9-0.1-0.2-0.00.00.2-0.20.11.50.10.6-0.1
Soleus weight1.54.511.63.42.92.62.6-2.51.8-1.81.62.80.10.1-0.1-0.30.30.32.43.4-2.61.9
Bone: stiffness0.20.41.2-0.4-0.1-0.1-0.10.10.2-0.10.2-0.9-0.60.7-0.7-0.60.60.5-1.1-0.90.9-0.6
Tibialis anterior weight0.20.62.1-1.3-0.9-1.0-1.41.4-1.20.6-0.6-0.10.5-0.20.20.1-0.1-0.4-1.1-0.20.0-0.0
Time to tail flick, vehicle, before self-admin0.60.62.6-0.1-0.2-0.50.1-0.2-0.21.0-1.0-1.60.7-1.01.00.7-0.7-0.80.7-0.91.1-0.5
Time to tail flick, vehicle, after self-admin0.30.43.1-0.0-0.1-0.30.1-0.1-0.10.7-0.7-1.81.0-0.50.50.9-0.9-0.70.1-0.30.7-0.1
Time to tail flick, test, before self-admin0.10.10.6-0.3-0.4-0.2-0.10.00.10.2-0.1-0.8-0.00.3-0.30.1-0.10.1-0.1-0.50.5-0.2
Time to tail flick, test, after self-admin0.10.10.50.20.50.00.3-0.40.6-0.00.0-0.4-0.10.2-0.20.4-0.4-0.20.7-0.40.4-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.4-0.4-0.3-0.60.6-0.40.0-0.0-0.00.40.2-0.20.3-0.3-0.1-0.60.3-0.20.2
Delta time to tail flick, test, before/after SA0.30.30.6-0.7-0.3-0.8-0.70.6-0.60.6-0.6-0.50.5-0.70.70.5-0.5-0.70.2-0.40.2-0.0
Tibia length2.56.912.73.53.53.43.6-3.63.4-3.03.02.2-2.52.2-2.2-2.42.42.5-0.00.9-0.2-0.8
Ambulatory time before self-admin0.20.21.20.40.70.40.5-0.50.5-0.60.50.6-0.20.2-0.2-0.00.00.01.10.4-0.50.5
Ambulatory time after self-admin0.70.82.41.01.61.01.2-1.31.0-1.11.10.1-0.90.8-0.8-0.90.90.80.1-0.30.6-0.6
Bone: tissue strength0.50.51.30.30.50.60.5-0.50.7-0.90.90.3-0.91.1-1.1-0.70.70.9-0.8-0.20.2-0.3
Total heroin consumption0.10.10.90.20.30.10.2-0.20.2-0.20.20.10.20.1-0.10.6-0.6-0.20.90.2-0.10.3
Bone: trabecular number1.11.84.0-1.7-1.5-1.7-2.02.0-1.91.4-1.4-0.81.4-1.21.21.1-1.1-1.40.10.2-0.60.9
Bone: trabecular spacing3.14.16.52.02.12.32.4-2.42.6-2.32.41.4-2.42.2-2.2-2.12.12.3-0.8-0.20.6-1.3
Bone: trabecular thickness1.51.93.0-1.4-1.6-1.5-1.71.7-1.71.5-1.6-0.61.6-1.41.41.4-1.4-1.50.60.4-0.91.1
Bone: trabecular tissue density0.71.02.20.60.61.00.7-0.71.1-1.11.11.2-1.51.2-1.2-1.41.41.3-0.80.2-0.2-0.2
Water consumed over 24 hours0.10.10.30.40.50.30.5-0.50.4-0.40.4-0.1-0.20.2-0.2-0.20.20.2-0.0-0.40.5-0.5
Number of responses in last shaping day0.60.72.30.80.91.00.4-0.30.5-0.70.71.2-0.70.3-0.3-0.90.90.60.01.5-1.50.3