Hub : Genes

Trappc13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Trappc13 0.05 0.04 9.9e-06 0.04 0.04 0.03 0.04 3.7e-05 1.5e-05 2.0e-04 1.3e-05
2 Brain mRNA stability Trappc13 0.03 0.03 1.6e-03 0.03 0.03 0.02 0.03 1.8e-03 1.5e-03 3.7e-03 9.8e-04
3 pVTA mRNA stability Trappc13 0.17 0.17 7.0e-09 0.11 0.02 0.11 0.01 6.7e-09 5.8e-03 2.1e-09 4.0e-02
4 BLA gene expression Trappc13 0.07 0.07 1.8e-03 0.05 0.01 0.03 0.04 1.6e-03 9.0e-02 1.0e-02 2.2e-03
5 PL mRNA stability Trappc13 0.07 0.05 5.3e-10 0.08 0.03 0.08 -0 4.1e-09 2.5e-04 5.4e-09 8.4e-01
6 RMTg gene expression Trappc13 0.12 0.1 1.4e-03 0.12 0.12 0.1 0.12 3.4e-04 4.5e-04 1.1e-03 5.0e-04
7 NAcc mRNA stability Trappc13 0.07 0.05 1.7e-13 0.08 0.07 0.07 0.07 3.8e-12 1.7e-11 3.4e-11 2.1e-10
8 pVTA gene expression Trappc13 0.04 0.04 2.8e-03 0.02 -0 0.02 -0 9.8e-03 5.2e-01 6.6e-03 9.3e-01
9 NAcc gene expression Trappc13 0.05 0.04 2.2e-08 0.04 0.05 0.04 0.05 5.5e-07 4.8e-08 3.6e-07 7.0e-08
10 IC mRNA stability Trappc13 0.17 0.13 1.6e-05 0.09 0.09 0.07 0.09 1.2e-04 1.1e-04 7.6e-04 1.5e-04
11 PL gene expression Trappc13 0.06 0.07 2.6e-05 0.04 0.05 0.04 0.05 4.9e-05 2.5e-06 6.7e-05 5.0e-06
12 Adipose gene expression Trappc13 0.06 0.05 1.8e-07 0.06 0.06 0.06 0.06 4.6e-07 7.6e-07 7.7e-07 7.5e-07
13 Brain gene expression Trappc13 0.25 0.17 0.0e+00 0.24 0.25 0.24 0.25 1.0e-22 4.7e-23 2.6e-22 3.6e-23
14 BLA mRNA stability Trappc13 0.12 0.1 5.4e-05 0.07 0.03 0.08 0.04 1.2e-04 7.4e-03 6.4e-05 4.0e-03
15 Adipose mRNA stability Trappc13 0.1 0.12 3.8e-05 0.04 0.03 0.04 0.04 6.1e-05 1.0e-04 6.6e-05 8.3e-05
16 Liver gene expression Trappc13 0.15 0.15 5.2e-06 0.05 0.04 0.03 0.04 4.2e-06 4.6e-05 1.8e-04 1.8e-05
17 OFC gene expression Trappc13 0.13 0.1 7.0e-03 0.09 -0 0.06 0 4.7e-03 3.5e-01 2.0e-02 3.3e-01
18 LHb gene expression Trappc13 0.31 0.2 1.1e-04 0.14 0 0.09 0.14 3.6e-04 2.6e-01 3.8e-03 3.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.61.11.4-1.0-1.0-1.01.0-1.01.0-1.01.01.0-1.01.00.91.1-1.21.11.11.11.1
Area under the delay curve0.30.41.50.20.60.5-0.60.8-0.50.8-0.3-0.60.6-0.4-0.2-0.81.2-0.2-0.2-0.3-0.7
BMI with tail2.07.08.7-2.6-2.3-2.42.0-2.52.7-2.72.72.7-2.72.82.82.7-2.43.03.02.92.8
BMI without tail0.31.01.5-1.0-0.6-0.90.4-1.01.2-0.91.01.1-1.11.11.21.0-0.91.21.21.21.1
Body weight3.816.720.94.24.44.4-4.64.1-4.14.0-4.0-4.14.1-4.0-3.9-4.04.1-3.9-3.9-3.8-4.0
Weight adjusted by age0.00.00.10.30.20.2-0.10.0-0.20.1-0.2-0.20.2-0.3-0.2-0.10.2-0.3-0.3-0.2-0.3
Bone surface0.00.00.10.10.20.2-0.30.1-0.10.10.00.0-0.00.00.00.00.00.10.1-0.0-0.0
Bone volume0.00.10.1-0.2-0.1-0.10.0-0.20.2-0.20.30.2-0.20.30.20.3-0.30.40.40.20.2
Breakpoint value in progressive ratio session3.34.04.9-2.1-2.2-2.02.1-2.01.7-2.02.01.9-1.91.92.12.0-2.11.91.91.82.2
Number of licking bursts2.03.33.9-1.8-1.8-1.71.6-1.81.9-1.91.81.9-1.91.92.01.8-1.71.91.91.71.6
Context. condit. distance diff. score1.72.02.71.31.61.6-1.61.5-1.51.5-1.2-1.41.4-1.3-1.1-1.41.5-1.3-1.3-1.4-1.4
Locomotion velocity, session 10.30.30.60.60.70.6-0.70.6-0.80.6-0.6-0.60.6-0.5-0.4-0.40.4-0.6-0.6-0.5-0.5
Locomotion distance, session 10.81.01.40.91.01.1-0.91.0-1.01.0-0.9-0.91.0-0.9-0.9-0.90.8-1.2-1.2-1.1-1.1
Locomotion velocity, session 24.45.16.22.42.42.3-2.32.3-2.32.2-2.3-2.22.2-2.2-2.1-2.11.9-2.5-2.5-2.1-2.1
Locomotion distance, session 20.71.01.30.91.11.0-1.11.1-1.11.1-0.9-1.01.0-0.9-0.8-0.90.9-1.0-1.0-0.9-0.9
Locomotion velocity, session 35.25.96.92.62.52.6-2.62.4-2.62.3-2.3-2.42.4-2.4-2.4-2.32.3-2.5-2.5-2.4-2.4
Locomotion distance, session 37.58.19.02.93.03.0-3.02.9-3.02.8-2.7-2.82.8-2.8-2.8-2.82.8-2.8-2.8-2.8-2.8
Stereotopy head waving bouts, day 30.30.40.90.70.30.5-0.50.3-0.40.4-0.7-0.50.5-0.7-0.8-0.50.3-1.0-1.0-0.6-0.6
Stereotopy head waving duration, day 30.00.00.10.1-0.3-0.10.1-0.30.2-0.3-0.00.2-0.20.0-0.00.2-0.4-0.1-0.10.10.1
Locomotion velocity, session 70.10.10.20.40.30.4-0.40.2-0.20.2-0.2-0.20.3-0.3-0.4-0.30.2-0.5-0.5-0.3-0.3
Locomotion distance, session 70.40.50.60.60.80.7-0.70.7-0.60.7-0.5-0.60.7-0.6-0.8-0.70.8-0.8-0.8-0.6-0.6
Stereotopy head waving bouts, day 70.00.00.10.3-0.10.1-0.1-0.2-0.1-0.2-0.10.0-0.0-0.1-0.10.1-0.3-0.3-0.3-0.1-0.1
Stereotopy head waving duration, day 70.10.20.40.60.20.4-0.30.2-0.30.2-0.4-0.30.3-0.5-0.6-0.30.1-0.6-0.6-0.4-0.5
Locomotion velocity, session 82.42.93.61.71.81.8-1.91.7-1.81.7-1.7-1.71.7-1.7-1.5-1.61.5-1.7-1.7-1.7-1.7
Locomotion distance, session 84.26.17.22.32.72.7-2.72.6-2.62.6-2.3-2.52.5-2.3-2.2-2.52.5-2.4-2.4-2.4-2.4
Degree of sensitization distance3.73.84.8-2.0-2.1-2.12.2-1.92.2-1.91.81.9-1.91.81.71.9-1.91.71.72.02.0
Degree of sensitization stereotypy0.00.00.10.1-0.2-0.00.1-0.2-0.0-0.20.10.1-0.10.10.10.2-0.3-0.1-0.10.00.0
Conditioned locomotion0.00.00.0-0.0-0.20.0-0.0-0.1-0.1-0.20.10.0-0.00.0-0.10.0-0.20.10.10.10.1
Cocaine response after cond. corrected1.72.02.61.41.41.4-1.41.4-1.41.4-1.4-1.41.4-1.4-1.3-1.51.6-1.3-1.3-1.5-1.4
Cocaine response after cond. not corrected2.32.83.21.61.71.7-1.71.7-1.61.7-1.6-1.71.7-1.6-1.6-1.71.8-1.6-1.6-1.8-1.7
Cocaine response before conditioning0.30.30.50.50.70.6-0.60.6-0.60.7-0.5-0.50.6-0.5-0.5-0.50.4-0.7-0.7-0.5-0.6
Saline control response1.31.72.21.41.51.4-1.51.3-1.41.4-1.3-1.31.3-1.3-1.1-1.21.2-1.3-1.3-1.2-1.3
Bone: connectivity density0.00.10.1-0.2-0.2-0.20.2-0.20.2-0.20.30.3-0.30.30.30.3-0.30.40.40.20.2
Bone: cortical apparent density0.00.00.10.10.10.1-0.10.1-0.00.1-0.1-0.10.1-0.1-0.2-0.10.2-0.3-0.3-0.1-0.1
Bone: cortical area0.20.30.40.60.50.6-0.60.4-0.50.4-0.6-0.50.5-0.6-0.7-0.40.4-0.5-0.5-0.5-0.6
Bone: cortical porosity2.42.63.8-1.4-1.7-1.81.7-1.71.5-1.71.31.5-1.51.41.71.8-1.91.31.31.71.7
Bone: cortical porosity2.32.43.6-1.3-1.7-1.71.7-1.71.5-1.71.31.5-1.51.41.61.7-1.91.21.21.61.6
Bone: cortical thickness0.10.20.40.60.30.4-0.30.3-0.30.2-0.5-0.40.4-0.5-0.6-0.30.3-0.6-0.6-0.5-0.6
Bone: cortical thickness1.11.31.81.31.31.1-1.31.3-1.31.2-1.2-1.21.2-1.1-0.8-1.21.3-0.8-0.8-1.0-1.1
Bone: cortical tissue density0.00.00.10.20.10.1-0.10.1-0.00.1-0.1-0.10.1-0.2-0.2-0.20.2-0.3-0.3-0.2-0.1
Condit. Reinf. active minus inactive responses1.51.62.6-1.2-1.6-1.41.6-1.51.6-1.51.11.3-1.31.10.91.2-1.40.80.81.11.1
Condit. Reinf. active-inactive response ratio1.51.72.7-1.2-1.6-1.41.6-1.51.6-1.51.21.3-1.31.20.91.3-1.40.80.81.01.0
Condit. Reinf. active responses0.20.20.5-0.4-0.7-0.60.7-0.60.7-0.60.30.5-0.50.30.10.4-0.40.10.10.40.4
Condit. Reinf. inactive responses1.11.31.61.21.21.2-1.21.2-1.21.2-1.2-1.21.2-1.1-1.1-1.21.3-1.0-1.0-1.0-1.0
Incentive salience index mean1.11.32.4-1.1-1.4-1.31.5-1.21.4-1.31.01.1-1.11.00.91.1-1.10.80.81.11.1
Condit. Reinf. lever presses0.20.30.6-0.6-0.7-0.70.8-0.50.6-0.50.50.5-0.50.50.50.4-0.40.60.60.50.5
Condit. Reinf. active minus inactive responses4.35.66.92.52.42.5-2.62.3-2.62.3-2.4-2.42.4-2.4-2.2-2.32.3-2.2-2.2-2.3-2.2
Condit. Reinf. active-inactive response ratio2.32.63.11.71.61.6-1.71.5-1.71.5-1.8-1.71.6-1.7-1.6-1.61.6-1.7-1.7-1.6-1.4
Condit. Reinf. active responses1.52.12.71.51.51.5-1.61.4-1.61.4-1.4-1.41.4-1.4-1.3-1.41.4-1.4-1.4-1.5-1.4
Condit. Reinf. inactive responses0.10.10.30.30.40.4-0.50.3-0.40.4-0.2-0.20.3-0.2-0.2-0.30.2-0.2-0.2-0.4-0.4
Condit. Reinf. lever presses1.92.73.41.61.51.7-1.61.5-1.61.5-1.6-1.61.6-1.7-1.6-1.61.7-1.6-1.6-1.8-1.7
Condit. Reinf. lever reinforcers received2.02.83.51.81.71.7-1.81.6-1.91.6-1.7-1.71.7-1.7-1.6-1.61.6-1.6-1.6-1.7-1.6
Conditioned reinforcement - actives2.13.65.42.02.32.1-2.21.9-1.81.8-1.8-1.81.8-1.8-1.9-1.72.1-1.8-1.8-1.7-1.7
Conditioned reinforcement - inactives1.11.72.91.21.41.5-1.21.2-0.91.2-1.1-1.21.2-1.2-1.7-1.21.5-1.3-1.3-1.4-1.4
Conditioned locomotion0.91.22.11.31.41.2-1.31.1-1.11.0-1.0-1.01.0-1.0-1.1-0.91.1-1.0-1.0-0.9-0.9
Patch foraging indifference point 0 sec3.87.18.32.72.52.7-2.62.5-2.32.7-2.8-2.62.6-2.7-2.8-2.72.9-2.5-2.5-2.9-2.9
Patch foraging indifference point AUC0.50.71.0-0.9-0.8-0.80.8-0.50.5-0.50.90.7-0.70.91.00.7-1.00.90.90.80.8
Delay disc. indifference point, 0s delay0.40.40.7-0.6-0.8-0.60.6-0.60.7-0.80.60.6-0.60.60.60.7-0.70.50.50.50.6
Delay disc. indifference point, 16s delay1.11.23.70.81.41.1-1.31.1-1.11.3-0.8-1.11.1-0.9-0.9-1.31.9-0.5-0.5-0.8-1.2
Delay disc. indifference point, 2s delay0.20.20.4-0.3-0.6-0.60.4-0.20.4-0.50.30.4-0.40.30.40.5-0.50.40.40.60.5
Delay disc. indifference point, 24s delay1.01.13.90.61.31.2-1.11.0-0.91.3-0.5-0.91.0-0.7-1.0-1.22.0-0.4-0.4-1.0-1.1
Delay disc. indifference point, 4s delay0.00.00.1-0.1-0.3-0.20.20.30.10.0-0.1-0.10.1-0.00.1-0.2-0.1-0.1-0.10.20.0
Delay disc. indifference point, 8s delay0.20.21.2-0.10.40.3-0.30.6-0.20.60.0-0.30.3-0.10.1-0.51.10.10.1-0.2-0.5
Indifference point function ln k3.05.36.22.32.22.2-2.12.2-2.12.2-2.4-2.32.3-2.4-2.5-2.22.4-2.4-2.4-2.3-2.3
Indifference point function log k3.05.36.22.32.22.2-2.12.2-2.12.2-2.4-2.32.3-2.4-2.5-2.22.4-2.4-2.4-2.3-2.3
Patch foraging total patch changes 0 sec4.58.59.73.02.82.9-2.82.7-2.62.9-3.1-2.92.9-3.0-3.1-3.03.0-2.8-2.8-3.1-3.1
Patch foraging total patch changes 12 sec0.00.00.1-0.10.00.00.10.30.10.2-0.1-0.10.1-0.00.1-0.10.10.10.1-0.1-0.0
Patch foraging total patch changes 18 sec0.00.00.00.20.00.1-0.20.10.1-0.0-0.1-0.10.0-0.10.1-0.00.10.20.2-0.2-0.2
Patch foraging total patch changes 24 sec0.61.11.41.00.81.0-0.81.0-1.01.2-1.2-1.11.1-1.1-1.1-1.20.9-1.1-1.1-1.2-1.2
Patch foraging total patch changes 6 sec0.91.41.81.11.01.1-0.91.3-0.91.3-1.3-1.21.2-1.2-1.2-1.31.2-1.2-1.2-1.3-1.3
Patch foraging time to switch 0 sec4.59.310.5-3.2-2.9-3.03.0-3.13.1-3.03.23.0-3.03.13.03.0-2.83.23.23.03.0
Patch foraging water rate 0 sec3.67.69.02.82.62.6-2.52.8-2.62.8-3.0-2.82.8-2.9-2.7-2.72.5-3.0-3.0-2.7-2.7
Patch foraging water rate 12 sec3.47.28.32.72.52.6-2.32.6-2.62.7-2.9-2.72.7-2.8-2.8-2.72.6-2.8-2.8-2.7-2.7
Patch foraging water rate 18 sec5.38.29.72.82.82.7-2.43.0-2.93.0-3.0-3.03.0-3.0-2.9-2.92.7-3.1-3.1-2.7-2.7
Patch foraging water rate 24 sec2.73.84.92.22.21.9-2.12.1-1.91.8-2.1-2.02.0-2.1-1.8-1.71.7-2.1-2.1-1.6-1.6
Patch foraging water rate 6 sec13.019.021.04.44.34.3-4.24.4-4.44.3-4.5-4.44.4-4.5-4.4-4.34.0-4.6-4.6-4.2-4.2
Seeking ratio, delayed vs. immediate footshock1.11.32.0-1.1-0.9-1.20.9-1.01.1-1.01.01.1-1.21.11.31.1-1.11.41.41.41.2
Distance traveled before self-admin0.71.01.70.90.80.8-0.81.0-0.91.3-1.1-1.01.0-1.0-0.9-1.20.6-1.1-1.1-0.8-1.1
Distance traveled after self-admin1.41.72.11.41.21.2-1.41.3-1.41.4-1.4-1.31.3-1.4-1.0-1.31.3-1.1-1.1-1.2-1.3
Extensor digitorum longus weight3.714.617.0-3.5-3.7-3.93.4-3.83.9-3.93.63.8-3.93.84.04.0-4.03.63.64.14.0
Bone: elastic displacement1.82.12.5-1.4-1.6-1.51.5-1.51.5-1.51.51.5-1.41.41.41.5-1.51.21.21.31.4
Bone: elastic work0.40.50.7-0.7-0.8-0.80.8-0.70.8-0.70.80.8-0.80.80.70.8-0.80.50.50.70.7
Bone: endosteal estimation0.40.81.20.81.11.0-1.11.0-0.91.0-0.8-0.90.9-0.8-0.9-0.91.0-0.6-0.6-0.8-0.8
Bone: endosteal perimeter0.00.00.10.20.30.3-0.30.2-0.20.2-0.1-0.20.2-0.1-0.2-0.20.4-0.0-0.0-0.2-0.2
Epididymis fat weight0.93.23.61.91.71.8-1.71.7-1.81.7-1.8-1.81.8-1.9-1.9-1.71.6-1.9-1.9-1.9-1.9
Delta time in closed arm before/after self-admin3.63.44.9-2.2-1.7-1.71.7-1.81.7-1.72.21.9-1.82.01.91.7-1.32.02.01.71.7
Delta time in open arm before/after self-admin0.20.20.3-0.3-0.4-0.50.5-0.30.5-0.30.30.4-0.40.30.40.4-0.50.30.30.60.5
Diff in mean of infusions in LGA sessions0.00.00.10.1-0.2-0.10.0-0.3-0.10.1-0.1-0.00.0-0.10.00.1-0.20.10.10.10.3
Delay discount exponential model param0.30.41.5-0.2-0.6-0.50.6-0.80.5-0.80.30.6-0.60.40.30.8-1.20.10.10.30.7
Extinction: sum of active levers before priming2.73.04.3-1.9-2.1-1.62.0-2.01.7-1.71.81.7-1.71.71.51.8-1.91.41.41.41.7
Active lever presses in extinction session 63.43.43.9-1.8-1.9-1.91.8-1.91.5-2.01.81.8-1.81.82.01.9-1.91.91.91.91.9
Bone: final force0.40.70.80.80.90.9-0.80.9-0.80.9-0.7-0.80.8-0.8-0.9-0.80.7-0.9-0.9-0.8-0.8
Bone: final moment0.71.11.31.01.11.1-1.01.1-1.01.1-0.9-1.01.0-1.0-1.1-1.00.9-1.1-1.1-1.0-1.1
Food consumed during 24 hour testing period0.91.21.71.10.90.9-0.81.2-1.01.1-1.3-1.21.1-1.2-1.2-1.10.9-1.3-1.3-1.1-1.1
Glucose0.20.30.7-0.6-0.7-0.60.8-0.80.8-0.60.30.6-0.60.40.20.5-0.50.40.40.30.3
Heart weight0.71.21.51.11.21.2-1.11.0-0.91.2-1.0-1.01.0-1.0-1.2-1.11.1-0.9-0.9-1.2-1.1
Delay discount hyperbolic model param0.30.31.0-0.3-0.4-0.40.5-0.80.5-0.70.40.6-0.60.40.30.7-1.00.20.20.30.6
Intermittent access intake day 1-15 change0.00.00.10.2-0.2-0.10.1-0.30.2-0.2-0.2-0.0-0.0-0.1-0.30.2-0.4-0.2-0.20.10.1
Intermittent access intake escalation0.00.10.30.50.10.2-0.20.1-0.10.2-0.5-0.30.3-0.4-0.6-0.20.1-0.4-0.4-0.1-0.1
Intermittent access intake escalation 20.20.30.6-0.3-0.5-0.50.5-0.70.6-0.60.30.4-0.50.40.20.6-0.70.30.30.70.7
Intermitt. access day 1 inactive lever presses0.31.32.1-1.2-1.0-1.11.2-1.31.4-1.31.21.2-1.21.10.81.2-1.01.01.00.90.9
Intermitt. access day 15 inactive lever presses0.51.11.4-1.2-1.0-1.11.2-1.01.1-0.91.11.0-1.01.10.91.1-1.01.01.01.11.1
Intermitt. access escalation Index0.20.30.80.60.40.6-0.70.6-0.90.4-0.5-0.50.6-0.6-0.4-0.50.0-0.8-0.8-0.3-0.4
Intermittent access day 1 total infusions1.42.33.91.52.01.8-1.81.6-1.41.3-1.2-1.41.4-1.3-1.6-1.41.7-1.3-1.3-1.5-1.4
Intermittent access day 15 total infusions2.33.45.12.01.92.0-1.91.7-1.61.7-1.9-1.81.8-1.9-2.3-1.71.8-1.8-1.8-1.8-1.7
Intermittent access terminal intake (last 3 days)1.31.83.11.41.31.5-1.41.2-1.21.2-1.3-1.31.3-1.3-1.8-1.21.2-1.2-1.2-1.3-1.2
Intermittent access total infusions3.64.25.32.12.22.2-2.12.1-1.92.0-2.0-2.02.0-2.0-2.3-2.02.1-1.9-1.9-2.1-1.9
Intermittent access day 1 locomotion2.63.34.62.02.01.9-1.91.8-1.81.6-1.8-1.81.7-1.8-2.1-1.71.6-1.9-1.9-1.8-1.7
Intermittent access day 15 total locomotion2.13.95.42.21.92.0-1.91.8-1.81.9-2.0-1.91.9-2.0-2.3-1.81.8-2.1-2.1-2.0-1.8
Intermittent access total locomotion5.06.08.12.72.52.5-2.52.5-2.42.4-2.5-2.42.4-2.5-2.8-2.32.2-2.5-2.5-2.3-2.1
Intermittent access standard deviation0.00.10.2-0.0-0.0-0.1-0.0-0.10.2-0.20.10.2-0.20.20.30.3-0.20.40.40.20.3
Left kidney weight2.712.613.63.63.43.6-3.53.4-3.53.5-3.6-3.53.5-3.6-3.5-3.53.3-3.7-3.7-3.6-3.6
Right kidney weight2.611.812.73.53.43.6-3.53.4-3.43.5-3.5-3.43.4-3.5-3.5-3.43.3-3.3-3.3-3.6-3.5
Cocaine induced anxiety0.71.01.40.80.91.0-0.91.1-1.01.1-0.9-1.01.0-0.9-0.9-1.11.2-0.8-0.8-1.1-1.2
Post-drug Anxiety0.50.50.80.60.70.6-0.60.9-0.70.9-0.7-0.80.8-0.7-0.5-0.80.9-0.6-0.6-0.8-0.9
Baseline Anxiety0.10.10.4-0.3-0.5-0.50.6-0.20.4-0.20.20.3-0.30.20.40.3-0.60.20.20.30.4
Tail length10.440.643.66.66.66.5-6.46.2-6.16.4-6.4-6.36.3-6.4-6.4-6.36.1-6.5-6.5-6.3-6.3
Length with tail15.467.171.38.48.48.4-8.48.1-8.28.2-8.1-8.28.2-8.2-8.0-8.18.1-8.1-8.1-8.0-8.1
Length without tail10.634.237.15.95.86.0-5.85.9-6.15.8-5.8-5.95.9-5.9-5.7-5.85.8-5.6-5.6-5.8-5.9
Times rat made contact with spout0.40.40.5-0.7-0.7-0.70.7-0.60.6-0.60.60.6-0.60.60.70.7-0.70.60.60.50.6
Lifetime Intake3.03.64.72.02.12.1-2.01.9-1.71.8-1.8-1.81.8-1.8-2.2-1.82.0-1.7-1.7-1.9-1.8
Liver weight, left5.69.312.73.32.92.9-2.82.9-2.72.8-3.4-3.03.0-3.2-3.4-2.92.7-3.6-3.6-3.0-3.0
Liver weight, right0.10.30.60.60.30.5-0.50.1-0.10.2-0.6-0.30.3-0.5-0.7-0.40.3-0.8-0.8-0.7-0.8
Locomotor activity0.30.41.00.40.80.7-0.60.8-0.80.6-0.5-0.60.6-0.6-0.5-0.71.0-0.3-0.3-0.8-0.7
Locomotor testing distance0.20.30.5-0.6-0.4-0.40.4-0.50.6-0.50.70.6-0.60.60.60.5-0.20.70.70.30.4
Locomotor testing rearing0.10.10.3-0.2-0.0-0.1-0.2-0.40.5-0.40.50.5-0.50.50.50.5-0.10.40.40.20.2
Locomotion in novel chamber0.81.01.5-1.2-1.1-1.21.2-0.91.0-0.91.10.9-0.91.01.21.0-0.80.80.81.20.8
Locomotion in novel chamber post-restriction0.00.10.1-0.20.0-0.1-0.1-0.00.3-0.20.40.2-0.20.30.40.10.10.40.40.20.1
Fecal boli incidents, locomotor time 11.11.62.6-1.5-1.1-1.01.1-1.41.1-1.41.61.4-1.41.41.01.3-1.01.31.31.01.0
Change in fecal boli incidents, locomotor task0.10.10.40.10.1-0.30.00.10.4-0.0-0.20.0-0.10.10.40.1-0.4-0.0-0.00.50.6
Time >=10cm from walls, locomotor time 11.81.93.0-1.3-0.9-1.31.1-1.61.7-1.61.41.5-1.61.51.31.5-1.01.41.41.41.4
Bouts of movement, locomotor time 10.50.61.2-0.9-0.9-0.80.9-0.70.6-0.50.80.7-0.70.70.60.6-0.41.11.10.60.4
Total resting periods, locomotor time 10.10.10.4-0.6-0.4-0.20.4-0.30.1-0.10.50.3-0.20.30.10.10.10.60.60.1-0.0
Rest time, locomotor task time 10.81.02.0-1.2-0.9-0.91.0-1.10.7-0.71.11.0-1.01.11.00.9-0.61.41.40.90.9
Distance moved, locomotor task time 11.01.52.61.61.41.1-1.31.4-1.01.0-1.5-1.31.2-1.3-1.0-1.00.9-1.3-1.3-1.0-1.0
Vertical activity count, locomotor time 10.30.71.61.30.90.6-1.11.2-0.90.6-1.2-1.00.9-1.0-0.4-0.60.4-0.9-0.9-0.4-0.4
Time >=10cm from walls, locomotor time 20.71.11.7-1.2-0.8-1.01.0-0.91.3-1.01.11.1-1.11.20.91.0-1.00.90.91.01.1
Bouts of movement, locomotor time 20.10.10.40.20.50.3-0.50.5-0.50.5-0.2-0.30.3-0.2-0.0-0.40.70.10.10.1-0.1
Total resting periods, locomotor time 20.10.10.5-0.3-0.0-0.2-0.0-0.0-0.10.10.20.1-0.10.20.40.10.20.70.70.50.3
Rest time, locomotor task time 23.03.85.6-2.0-1.9-1.81.7-2.41.7-2.02.12.1-2.02.01.82.0-1.52.12.11.91.6
Distance moved, locomotor task time 21.31.62.81.61.51.2-1.51.7-1.21.0-1.4-1.41.3-1.3-0.9-1.00.9-1.3-1.3-1.0-0.8
Vertical activity count, locomotor time 20.20.20.60.80.50.2-0.60.8-0.30.0-0.7-0.50.5-0.5-0.1-0.1-0.3-0.6-0.6-0.10.2
Light reinforcement 11.94.65.72.32.02.3-2.41.8-2.22.2-2.3-2.02.1-2.2-2.2-2.22.0-2.1-2.1-2.2-2.1
Light reinforcement 20.00.10.2-0.2-0.3-0.10.0-0.50.2-0.40.30.4-0.40.30.00.4-0.30.10.10.20.2
Bone: marrow area0.40.81.20.81.11.0-1.11.0-0.91.0-0.8-0.90.9-0.8-0.9-0.91.0-0.6-0.6-0.8-0.8
Bone: maximum diameter0.20.40.5-0.6-0.5-0.50.4-0.60.5-0.70.60.6-0.60.60.50.7-0.60.70.70.70.6
Bone: maximum force0.10.20.40.40.50.5-0.40.5-0.40.5-0.3-0.50.5-0.4-0.6-0.50.4-0.4-0.4-0.5-0.5
Bone: maximum moment0.30.60.80.70.80.8-0.70.8-0.70.8-0.6-0.70.7-0.7-0.9-0.70.7-0.7-0.7-0.8-0.8
Mean time between licks in bursts0.10.10.4-0.4-0.4-0.40.5-0.20.6-0.40.30.3-0.40.40.30.3-0.40.30.30.30.3
Mean num. licks in bursts1.42.22.71.41.41.4-1.11.5-1.51.6-1.5-1.51.5-1.5-1.6-1.41.4-1.6-1.6-1.4-1.3
Cd content in liver2.22.43.21.71.51.5-1.41.4-1.31.4-1.6-1.51.5-1.6-1.7-1.51.6-1.8-1.8-1.7-1.7
Co content in liver0.00.00.1-0.0-0.1-0.00.1-0.10.1-0.10.20.1-0.10.10.00.1-0.3-0.1-0.10.10.1
Cu content in liver0.10.10.30.40.10.3-0.10.1-0.10.1-0.3-0.20.3-0.3-0.5-0.20.1-0.5-0.5-0.4-0.4
Fe content in liver1.21.41.51.21.21.2-1.21.2-1.21.2-1.2-1.21.2-1.2-1.2-1.21.1-1.2-1.2-1.1-1.2
K content in liver1.01.01.81.01.31.1-1.31.2-1.31.2-0.8-1.01.1-0.9-0.7-1.01.0-0.6-0.6-0.7-0.6
Mg content in liver0.10.10.2-0.20.1-0.0-0.20.2-0.30.20.30.0-0.00.20.40.10.00.30.30.40.4
Mn content in liver0.50.60.70.80.60.7-0.70.7-0.80.7-0.8-0.70.7-0.8-0.8-0.70.6-0.8-0.8-0.7-0.7
Na content in liver0.00.00.1-0.3-0.2-0.10.2-0.10.1-0.10.30.2-0.20.20.00.2-0.20.20.20.20.3
Rb content in liver1.82.03.21.31.21.6-1.21.2-1.41.2-1.4-1.31.4-1.4-1.8-1.41.3-1.5-1.5-1.7-1.7
Se content in liver0.81.01.3-0.9-1.0-1.10.9-0.91.0-0.90.90.9-0.90.91.11.0-1.11.11.11.11.1
Sr content in liver2.52.22.7-1.5-1.4-1.41.4-1.41.4-1.41.61.5-1.51.61.41.5-1.41.41.41.61.6
Zn content in liver0.10.10.30.40.40.4-0.40.4-0.40.4-0.3-0.40.4-0.3-0.3-0.40.5-0.2-0.2-0.4-0.4
Bone: minimum diameter2.64.75.52.22.22.2-2.02.1-2.12.1-2.2-2.22.2-2.2-2.3-2.22.2-2.2-2.2-2.2-2.3
Time in familiar zone, hab. session 14.44.24.62.22.12.1-2.12.0-2.12.0-2.1-2.12.1-2.1-2.0-2.12.1-2.0-2.0-2.0-2.0
Time in novel zone, hab. session 16.26.26.8-2.6-2.5-2.52.6-2.52.5-2.52.52.5-2.52.52.52.6-2.52.42.42.42.4
Total zone transitions, hab. session 10.00.00.0-0.00.10.0-0.10.2-0.10.20.0-0.10.10.00.2-0.00.00.10.10.10.1
Total locomotion distance, hab. session 10.10.10.40.10.40.3-0.50.4-0.60.4-0.0-0.20.2-0.10.1-0.20.30.20.20.20.2
Locomotion velocity, hab. session 10.10.10.30.10.40.3-0.50.3-0.60.3-0.0-0.20.2-0.10.1-0.20.20.20.20.20.2
Time in familiar zone, hab. session 21.81.92.71.51.51.5-1.61.4-1.51.4-1.3-1.41.4-1.4-1.3-1.41.5-1.2-1.2-1.2-1.2
Time in novel zone, hab. session 22.22.22.8-1.6-1.6-1.61.7-1.51.6-1.51.51.5-1.51.51.41.6-1.61.21.21.31.3
Total zone transitions, hab. session 20.10.10.20.20.40.3-0.40.4-0.40.4-0.2-0.30.3-0.20.0-0.10.2-0.2-0.2-0.2-0.1
Total locomotion distance, hab. session 20.10.10.2-0.20.0-0.1-0.10.0-0.2-0.00.30.1-0.10.30.40.2-0.20.40.40.50.5
Locomotion velocity, hab. session 20.00.10.30.10.30.2-0.40.3-0.50.4-0.1-0.20.2-0.10.1-0.20.10.10.10.10.1
Novel to familiar place preference ratio1.92.12.8-1.6-1.6-1.41.6-1.61.7-1.51.61.6-1.51.51.31.5-1.31.31.31.11.1
Novelty place preference1.41.52.2-1.3-1.4-1.21.3-1.41.5-1.31.31.3-1.31.21.11.3-1.21.01.00.90.9
Time in novel zone, NPP test1.61.72.3-1.4-1.4-1.21.4-1.51.5-1.41.41.4-1.41.31.21.4-1.21.11.11.01.0
Total zone transitions, NPP test1.31.82.41.41.51.4-1.51.4-1.51.4-1.3-1.41.4-1.3-1.1-1.41.3-1.2-1.2-1.2-1.2
Total locomotion distance, NPP test0.10.10.40.30.50.4-0.60.4-0.70.4-0.2-0.40.4-0.3-0.1-0.40.4-0.1-0.1-0.2-0.2
Locomotion velocity, NPP test0.60.81.40.91.00.9-1.11.0-1.21.0-0.8-0.90.9-0.8-0.6-0.90.9-0.7-0.7-0.7-0.7
Intraocular pressure3.34.87.1-1.9-2.2-2.12.1-2.62.3-2.72.12.3-2.32.11.72.4-2.41.71.72.22.3
Delta distance traveled before/after self-admin1.01.11.91.21.21.1-1.31.1-1.20.7-1.0-1.01.0-1.0-0.8-0.91.4-0.7-0.7-1.1-0.9
Delta ambulatory time before/after self-admin0.81.01.81.01.11.1-1.21.1-1.20.8-1.0-1.01.0-1.0-0.8-0.91.3-0.7-0.7-1.1-1.0
Parametrial fat weight0.00.10.20.20.40.3-0.50.2-0.20.3-0.3-0.20.2-0.2-0.2-0.30.4-0.1-0.1-0.2-0.3
Pavlov. Cond. lever latency0.00.00.0-0.0-0.1-0.00.0-0.10.1-0.1-0.00.1-0.10.00.10.1-0.10.10.1-0.0-0.0
Pavlov. Cond. magazine entry latency1.51.92.81.41.61.4-1.51.7-1.51.7-1.3-1.51.5-1.3-1.1-1.51.5-1.2-1.2-1.0-1.1
Pavlov. Cond. change in total contacts3.43.64.01.91.91.9-1.82.0-1.91.9-1.8-1.91.9-1.9-1.9-2.01.8-2.0-2.0-1.8-1.8
Pavlov. Cond. index score0.50.71.00.80.90.8-0.81.0-0.91.0-0.7-0.90.9-0.8-0.7-0.90.8-0.7-0.7-0.6-0.6
Pavlov. Cond. latency score0.20.20.30.40.50.4-0.40.6-0.50.6-0.3-0.50.5-0.4-0.4-0.50.5-0.4-0.4-0.3-0.3
Pavlov. Cond. lever contacts0.50.60.80.80.80.8-0.80.9-0.90.8-0.7-0.80.8-0.8-0.8-0.80.8-0.8-0.8-0.7-0.7
Pavlov. Cond. magazine entry number2.63.34.5-1.8-2.0-1.91.9-2.12.0-2.11.61.9-1.91.71.61.9-1.91.61.61.51.5
Pavlov. Cond. intertrial magazine entries5.46.57.4-2.6-2.7-2.62.6-2.62.6-2.72.42.6-2.62.52.32.6-2.52.42.42.52.5
Pavlov. Cond. lever-magazine prob. diff.0.70.91.30.91.10.9-1.01.1-1.01.1-0.8-1.01.0-0.9-0.9-1.01.0-0.9-0.9-0.7-0.7
Pavlov. Cond. response bias2.32.83.81.71.81.7-1.81.9-1.91.8-1.5-1.81.8-1.6-1.5-1.81.7-1.5-1.5-1.4-1.4
Pavlov. Cond. lever latency2.73.74.8-1.8-1.9-2.01.9-1.91.9-2.01.81.9-1.91.91.92.0-2.11.71.72.22.1
Pavlov. Cond. magazine entry latency0.91.11.81.01.31.1-1.21.2-1.21.2-1.0-1.11.1-1.0-0.6-1.11.3-0.7-0.7-1.0-0.9
Pavlov. Cond. change in total contacts4.57.38.52.72.72.7-2.62.7-2.62.8-2.7-2.72.7-2.7-2.6-2.72.9-2.5-2.5-2.9-2.7
Pavlov. Cond. index score2.53.44.51.71.91.9-1.91.9-1.92.0-1.8-1.91.9-1.8-1.6-1.92.1-1.5-1.5-2.0-1.9
Pavlov. Cond. latency score2.63.44.71.72.02.0-1.91.9-1.92.0-1.7-1.81.8-1.8-1.6-1.92.2-1.5-1.5-2.0-1.9
Pavlov. Cond. lever contacts2.12.93.91.61.61.8-1.61.6-1.61.7-1.6-1.71.7-1.7-1.7-1.71.9-1.5-1.5-2.0-1.9
Pavlov. Cond. magazine entry number1.82.33.2-1.4-1.7-1.61.8-1.71.8-1.71.41.6-1.61.41.01.6-1.71.01.01.41.3
Pavlov. Cond. intertrial magazine entries0.10.10.20.30.10.3-0.20.0-0.20.0-0.3-0.10.2-0.3-0.4-0.1-0.1-0.5-0.5-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.2.63.54.71.82.02.0-1.91.9-1.92.0-1.8-1.91.9-1.8-1.6-1.92.2-1.5-1.5-2.0-1.9
Pavlov. Cond. response bias1.52.12.71.41.41.5-1.51.5-1.51.5-1.4-1.51.5-1.4-1.3-1.51.6-1.2-1.2-1.6-1.5
Time in closed arm before self-admin0.20.30.70.60.40.3-0.50.8-0.60.7-0.7-0.60.5-0.5-0.3-0.60.4-0.3-0.3-0.3-0.5
Time in closed arm after self-admin0.10.10.4-0.2-0.2-0.3-0.10.0-0.0-0.10.40.3-0.30.40.60.3-0.30.50.50.70.5
Time in open arm before self-admin0.20.20.60.20.50.6-0.20.2-0.20.2-0.1-0.30.3-0.3-0.7-0.30.4-0.5-0.5-0.8-0.3
Time in open arm after self-admin0.50.60.9-0.8-0.8-0.71.0-0.91.0-0.90.70.8-0.80.70.40.8-0.70.60.60.50.8
Bone: periosteal estimation0.30.60.90.80.90.9-1.00.8-0.80.8-0.8-0.80.8-0.8-0.9-0.70.8-0.6-0.6-0.7-0.8
Bone: periosteal perimeter0.10.30.40.50.60.6-0.60.5-0.50.4-0.4-0.50.5-0.4-0.6-0.50.6-0.4-0.4-0.5-0.6
Bone: post-yield work0.20.30.40.50.60.5-0.40.6-0.50.5-0.6-0.50.5-0.5-0.6-0.50.5-0.3-0.3-0.5-0.5
Progressive ratio test 1 active lever presses2.53.14.91.92.21.9-2.01.6-1.41.6-1.7-1.61.6-1.7-1.9-1.61.9-1.8-1.8-1.7-1.6
Progressive ratio test 1 breakpoint2.83.55.32.02.32.0-2.11.8-1.51.7-1.8-1.71.7-1.8-2.0-1.72.0-1.9-1.9-1.8-1.7
Progressive ratio test 1 inactive lever presses1.01.52.11.21.41.2-1.11.2-0.81.2-1.2-1.21.2-1.2-1.5-1.21.3-1.3-1.3-1.1-1.0
Progressive ratio test 2 active lever presses2.73.14.61.82.22.0-2.11.8-1.61.7-1.7-1.71.7-1.6-1.9-1.62.0-1.6-1.6-1.5-1.5
Progressive ratio test 2 breakpoint2.93.35.01.92.22.0-2.11.9-1.61.8-1.7-1.81.7-1.7-1.9-1.72.1-1.6-1.6-1.5-1.5
Progressive ratio test 2 inactive lever presses0.91.42.61.31.61.4-1.41.0-0.91.0-1.1-1.01.0-1.1-1.6-0.91.3-1.2-1.2-1.0-0.8
Incentive Sensitization - Responses2.63.74.21.91.92.0-2.02.1-2.02.0-1.9-2.01.9-1.9-2.0-1.92.0-1.8-1.8-1.7-1.8
Incentive Sensitization - Breakpoint2.33.03.51.71.71.8-1.71.9-1.81.8-1.7-1.81.8-1.7-1.9-1.71.7-1.6-1.6-1.5-1.6
Sum of active levers in priming session hrs 5-62.11.92.4-1.3-1.5-1.41.4-1.51.1-1.31.21.4-1.41.31.41.3-1.51.51.51.21.6
Progressive ratio0.10.10.40.40.30.5-0.60.4-0.30.3-0.2-0.30.3-0.3-0.6-0.30.2-0.4-0.4-0.3-0.4
Food seeking constrained by brief footshock2.43.03.81.51.51.6-1.32.0-1.72.0-1.8-1.81.8-1.8-1.7-1.91.7-1.5-1.5-1.9-1.8
Seeking ratio, punishment vs. effort0.50.81.10.80.80.7-0.50.9-0.91.0-1.0-0.90.9-0.9-0.8-1.01.0-0.6-0.6-1.1-0.9
Retroperitoneal fat weight0.10.30.50.40.40.5-0.50.3-0.60.5-0.7-0.50.5-0.6-0.5-0.50.3-0.5-0.5-0.5-0.6
Reaction time number correct6.412.415.84.03.63.5-3.93.6-3.83.5-3.7-3.63.5-3.6-3.3-3.33.0-3.5-3.5-3.1-3.1
Reaction time mean minus median0.00.00.20.10.20.3-0.40.0-0.2-0.10.1-0.00.00.0-0.10.00.20.30.30.00.1
Reaction time mean minus median AUC0.10.20.50.60.70.6-0.70.5-0.70.3-0.4-0.40.4-0.4-0.5-0.30.5-0.1-0.1-0.3-0.2
Reaction time num false alarms0.30.40.7-0.7-0.9-0.50.6-0.70.8-0.70.60.7-0.70.70.20.6-0.60.60.60.40.5
Reaction time num false alarms AUC0.60.91.2-1.0-1.1-0.80.9-1.11.1-1.01.01.1-1.01.00.61.0-0.90.90.90.70.9
Reaction time trials correct on left6.412.415.84.03.63.5-3.93.6-3.83.5-3.7-3.63.5-3.6-3.3-3.33.0-3.5-3.5-3.1-3.1
Reaction time trials on left6.612.516.04.03.63.5-3.93.6-3.83.5-3.7-3.63.6-3.6-3.3-3.43.0-3.6-3.6-3.1-3.1
Reaction time mean1.62.53.1-1.5-1.5-1.41.4-1.71.7-1.61.71.7-1.71.61.51.6-1.41.81.81.51.5
Reaction time mean AUC1.42.22.9-1.5-1.4-1.31.2-1.51.5-1.51.61.5-1.51.61.41.5-1.31.71.71.41.4
Median of all reaction times2.83.94.5-2.0-2.0-1.91.9-2.12.1-2.02.12.1-2.02.02.02.0-1.82.02.01.81.9
Reaction time omissions0.30.40.60.70.50.7-0.70.4-0.60.5-0.7-0.60.6-0.7-0.6-0.50.4-0.7-0.7-0.8-0.7
Reaction time false alarm rate5.17.08.5-2.9-2.8-2.52.8-2.82.9-2.72.72.8-2.72.72.22.6-2.42.62.62.22.4
Reaction time premature initiation rate3.95.46.52.22.32.3-2.12.4-2.32.3-2.2-2.32.3-2.3-2.2-2.32.6-2.2-2.2-2.5-2.3
Reaction time premature initiations9.016.017.84.24.24.1-4.14.1-4.24.0-3.9-4.04.0-4.0-3.8-3.94.0-3.9-3.9-3.9-3.7
Std. dev. reaction times0.20.30.7-0.3-0.3-0.30.1-0.60.5-0.70.60.6-0.60.60.50.7-0.40.80.80.60.7
Reaction time trials completed6.612.516.04.03.63.5-3.93.6-3.83.5-3.7-3.63.6-3.6-3.3-3.43.0-3.6-3.6-3.1-3.1
Reaction time trials AUC6.011.414.73.83.43.4-3.73.4-3.63.3-3.6-3.43.4-3.4-3.2-3.22.9-3.4-3.4-3.0-3.0
Run reversals in cocaine runway, females0.70.71.3-1.0-0.7-1.11.1-0.60.6-0.50.70.7-0.70.71.00.7-0.51.01.01.10.8
Run reversals in cocaine runway, males0.10.10.4-0.10.60.4-0.60.4-0.50.20.2-0.00.10.20.1-0.10.50.40.40.10.2
Latency to leave start box in cocaine runway2.42.83.3-1.7-1.8-1.61.3-1.71.5-1.51.61.7-1.61.71.81.5-1.71.81.81.81.6
Latency to leave start box in cocaine runway, F0.20.30.4-0.5-0.6-0.50.3-0.60.5-0.30.40.5-0.50.50.60.3-0.50.70.70.60.4
Latency to leave start box in cocaine runway, M2.82.63.2-1.7-1.6-1.61.4-1.41.3-1.71.71.5-1.51.61.81.7-1.71.61.61.71.7
Std. dev. time between licks in bursts0.71.01.6-0.9-0.9-0.90.7-0.80.8-1.01.01.0-1.01.01.31.0-1.01.11.11.01.0
Total sessions with >9 infusions1.11.32.01.21.41.3-1.31.0-0.90.9-1.1-1.01.0-1.0-1.3-1.11.3-1.1-1.1-1.1-1.1
Short access day 1 total inactive lever presses1.11.52.71.10.91.3-0.81.2-0.81.1-1.2-1.21.2-1.3-1.7-1.21.1-1.3-1.3-1.5-1.4
Short access day 10 total inactive lever presses0.10.30.5-0.7-0.7-0.60.7-0.70.5-0.50.60.5-0.50.50.60.5-0.40.70.70.50.5
Short access day 1 total infusions0.60.81.90.81.01.1-0.90.8-0.50.8-0.8-0.80.8-0.8-1.4-0.91.1-0.9-0.9-1.0-0.9
Short access day 10 total infusions1.92.43.71.61.91.8-1.81.5-1.41.5-1.4-1.41.4-1.4-1.6-1.51.8-1.3-1.3-1.6-1.5
Short access total infusions1.51.92.51.41.51.6-1.51.4-1.11.3-1.3-1.31.3-1.3-1.6-1.31.5-1.2-1.2-1.4-1.3
Short access day 1 locomotion0.20.20.70.60.70.7-0.70.3-0.40.2-0.4-0.30.3-0.4-0.8-0.30.5-0.4-0.4-0.4-0.3
Short access day 10 total locomotion0.40.81.3-0.7-0.8-0.70.7-1.10.7-1.10.91.0-1.00.90.61.0-0.91.01.00.80.9
Short access total locomotion0.40.50.90.90.90.8-1.00.5-0.70.4-0.7-0.60.5-0.6-1.0-0.50.5-0.6-0.6-0.6-0.5
One hour access (0.3 mA shock)2.63.05.11.92.22.0-2.11.5-1.61.4-1.6-1.61.6-1.6-2.1-1.41.7-1.7-1.7-1.4-1.4
Compulsive drug intake1.61.92.7-1.5-1.3-1.51.3-1.41.3-1.21.41.4-1.41.51.71.4-1.11.41.41.51.5
One hour access (shock baseline)3.65.57.82.52.72.6-2.62.2-2.22.1-2.3-2.22.3-2.3-2.8-2.12.2-2.3-2.3-2.3-2.2
Social response proportion0.00.00.1-0.00.20.1-0.3-0.10.1-0.30.20.2-0.20.20.20.2-0.10.10.10.10.1
Social responses1.21.52.91.11.71.3-1.71.5-1.61.3-1.1-1.21.2-1.1-0.7-1.21.4-0.9-0.9-0.9-0.9
Social time0.00.00.10.0-0.10.00.0-0.1-0.1-0.3-0.00.1-0.1-0.0-0.20.1-0.2-0.2-0.2-0.00.1
Soleus weight0.20.51.0-0.5-0.9-0.60.7-0.90.9-1.00.60.7-0.70.60.30.7-0.90.50.50.40.4
Bone: stiffness0.20.30.60.40.60.7-0.40.6-0.60.6-0.4-0.60.6-0.5-0.7-0.60.5-0.4-0.4-0.7-0.8
Tibialis anterior weight2.79.211.4-2.9-2.9-3.22.7-2.83.0-3.02.93.0-3.03.03.43.0-2.93.33.33.23.2
Time to tail flick, vehicle, before self-admin1.92.02.71.51.11.4-1.21.1-1.51.4-1.5-1.41.4-1.5-1.6-1.41.1-1.6-1.6-1.6-1.4
Time to tail flick, vehicle, after self-admin0.00.10.2-0.2-0.10.00.30.2-0.00.5-0.1-0.20.2-0.1-0.1-0.3-0.4-0.3-0.3-0.10.2
Time to tail flick, test, before self-admin0.10.10.2-0.3-0.2-0.20.3-0.30.4-0.50.40.3-0.30.30.20.4-0.40.10.10.30.4
Time to tail flick, test, after self-admin1.51.52.9-1.0-1.2-1.51.2-1.41.1-1.10.91.2-1.21.11.41.2-1.70.90.91.51.4
Delta time to tail flick, vehicle, before/after SA1.21.11.9-1.4-1.2-1.11.2-0.71.1-0.71.10.9-0.91.11.10.9-1.40.90.91.11.2
Delta time to tail flick, test, before/after SA0.00.00.2-0.0-0.1-0.30.0-0.1-0.00.1-0.10.0-0.00.10.4-0.0-0.10.20.20.20.0
Tibia length7.119.422.44.54.14.5-4.14.1-4.14.2-4.5-4.34.4-4.5-4.6-4.44.0-4.7-4.7-4.7-4.7
Ambulatory time before self-admin0.10.20.40.50.30.2-0.30.4-0.40.7-0.6-0.50.5-0.5-0.2-0.50.1-0.5-0.5-0.2-0.4
Ambulatory time after self-admin0.91.11.61.10.90.9-1.01.2-1.11.2-1.2-1.11.1-1.1-0.7-1.21.3-0.7-0.7-1.0-1.2
Bone: tissue strength0.80.81.6-0.9-1.1-0.91.2-0.90.9-0.90.90.9-0.90.80.60.9-1.30.30.30.80.9
Total heroin consumption1.51.82.4-1.2-1.5-1.41.4-1.51.3-1.41.01.3-1.31.21.41.3-1.51.21.21.31.4
Bone: trabecular number0.00.00.0-0.10.1-0.0-0.00.0-0.00.10.00.0-0.00.10.00.0-0.10.20.20.10.1
Bone: trabecular spacing0.10.10.3-0.2-0.5-0.50.6-0.40.5-0.50.10.3-0.30.20.30.3-0.30.10.10.20.2
Bone: trabecular thickness0.60.71.0-0.9-0.8-0.70.7-0.90.8-0.81.00.9-0.90.90.81.0-1.00.80.80.90.9
Bone: trabecular tissue density2.73.94.8-2.2-2.2-2.02.2-2.11.9-2.02.02.0-2.01.92.12.0-2.01.81.81.71.8
Water consumed over 24 hours0.40.50.7-0.8-0.8-0.80.8-0.70.8-0.70.70.7-0.70.70.70.8-0.80.70.70.60.7
Number of responses in last shaping day0.40.51.0-0.6-0.1-0.50.4-0.71.0-0.90.70.8-0.80.80.50.8-0.40.60.60.80.8