Togaram2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Togaram2 0.09 0.09 1.2e-07 0.05 0.05 0.04 0.05 8.6e-07 2.4e-06 3.5e-05 8.5e-07
2 Adipose gene expression Togaram2 0.13 0.1 6.0e-09 0.07 0.07 0.07 0.07 2.5e-08 1.8e-08 3.1e-08 4.5e-08
3 PL isoform ratio XM_017594410.2 0.05 0.04 6.8e-05 0.03 0.04 0.03 0.03 2.6e-04 8.4e-05 9.0e-04 2.5e-04
4 Brain isoform ratio XM_017594410.2 0.05 0.04 7.4e-06 0.04 0.05 0.05 0.05 1.1e-04 1.7e-05 2.6e-05 2.3e-05
5 PL intron excision ratio chr6_23816601_23828169 0.03 0.03 6.1e-04 0.02 0.02 0.02 0.02 2.3e-03 1.7e-03 5.9e-03 4.6e-03
6 Liver intron excision ratio chr6_23786077_23786825 0.02 0.02 4.4e-03 0.02 0.02 0.02 0.02 3.7e-03 2.5e-03 2.9e-03 2.7e-03
7 Liver isoform ratio XM_017594408.2 0.03 0.02 4.2e-03 0.01 0.02 0.01 0.01 7.8e-03 1.9e-03 8.1e-03 8.6e-03
8 OFC gene expression Togaram2 0.33 0.22 1.0e-05 0.15 0.2 0.13 0.15 2.0e-04 2.2e-05 5.4e-04 2.3e-04
9 Brain intron excision ratio chr6_23816601_23828284 0.17 0.09 0.0e+00 0.2 0.2 0.2 0.2 2.0e-18 1.5e-18 5.2e-18 3.8e-18
10 NAcc intron excision ratio chr6_23816601_23828169 0.78 0 0.0e+00 0.16 0.16 0.15 0.16 4.8e-18 7.5e-18 5.7e-17 1.5e-17
11 NAcc isoform ratio XM_017594410.2 0.06 0.05 7.0e-08 0.07 0.07 0.06 0.07 1.7e-08 2.6e-08 6.2e-08 3.0e-08
12 BLA intron excision ratio chr6_23816601_23828169 0.33 0.22 6.6e-09 0.13 0.1 0.1 0.12 2.4e-07 3.5e-06 6.2e-06 3.5e-07
13 Liver mRNA stability Togaram2 0.06 0.06 2.4e-06 0.05 0.05 0.05 0.05 3.8e-06 4.0e-06 5.7e-06 6.6e-06
14 pVTA isoform ratio XM_017594410.2 0.31 0.29 4.6e-03 0.06 0.04 0.04 0.06 1.2e-03 6.3e-03 5.8e-03 2.1e-03
15 Liver gene expression Togaram2 0.16 0.12 7.8e-11 0.09 0.08 0.07 0.09 6.8e-10 2.0e-09 2.1e-08 9.1e-10
16 NAcc isoform ratio XM_002729599.6 0.02 0.02 8.8e-03 0.01 0.01 0.01 0.01 1.1e-02 5.0e-02 1.6e-02 2.6e-02
17 Brain intron excision ratio chr6_23816601_23828169 0.18 0.1 0.0e+00 0.22 0.21 0.21 0.21 3.8e-20 1.5e-19 2.8e-19 1.8e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density5.79.512.4-3.43.23.13.13.0-3.0-3.03.0-3.1-3.0-3.0-3.12.8-2.8-3.13.5-3.0
Area under the delay curve1.31.41.9-1.41.31.21.21.2-1.2-1.21.1-1.2-1.1-1.1-1.11.2-1.2-1.21.2-1.2
BMI with tail0.31.02.11.5-1.0-1.1-1.0-1.01.01.0-1.00.90.90.90.7-1.11.20.9-0.80.8
BMI without tail0.10.20.70.4-0.4-0.6-0.5-0.50.50.5-0.50.30.30.30.3-0.70.80.1-0.40.2
Body weight1.66.77.32.5-2.6-2.7-2.7-2.72.72.7-2.72.62.62.62.6-2.62.62.5-2.12.6
Weight adjusted by age0.20.20.80.4-0.4-0.5-0.4-0.40.40.4-0.50.40.30.30.4-0.50.50.3-0.90.4
Bone surface2.13.85.7-2.42.02.01.91.9-1.9-1.91.9-1.8-1.9-1.9-1.71.9-1.9-1.72.4-1.7
Bone volume2.74.67.4-2.62.32.12.12.1-2.1-2.12.0-2.1-2.1-2.1-2.02.0-2.0-2.02.7-1.9
Breakpoint value in progressive ratio session0.80.81.3-1.11.00.90.90.9-0.9-0.90.9-0.9-0.9-0.9-1.00.7-0.8-0.91.1-1.0
Number of licking bursts0.30.30.5-0.70.70.60.50.5-0.5-0.50.4-0.5-0.4-0.4-0.40.5-0.5-0.70.7-0.5
Context. condit. distance diff. score0.20.31.21.1-0.5-0.3-0.4-0.40.40.3-0.30.50.50.50.5-0.20.20.7-0.50.7
Locomotion velocity, session 10.10.10.10.0-0.1-0.3-0.3-0.30.30.3-0.30.20.20.20.2-0.30.30.2-0.20.2
Locomotion distance, session 12.22.83.2-1.81.71.61.71.7-1.7-1.71.7-1.7-1.8-1.8-1.71.6-1.6-1.61.5-1.7
Locomotion velocity, session 20.10.20.3-0.1-0.3-0.4-0.4-0.40.40.4-0.40.40.50.50.5-0.30.30.6-0.20.6
Locomotion distance, session 20.00.00.5-0.70.20.00.10.0-0.0-0.00.0-0.1-0.1-0.1-0.1-0.10.1-0.10.2-0.1
Locomotion velocity, session 30.40.51.0-1.00.60.70.60.7-0.6-0.60.6-0.6-0.3-0.3-0.70.8-0.8-0.70.8-0.7
Locomotion distance, session 31.11.22.2-1.51.21.11.11.1-1.1-1.01.0-1.1-1.1-1.1-1.10.9-0.9-1.21.2-1.2
Stereotopy head waving bouts, day 31.01.21.8-1.31.11.21.11.1-1.1-1.11.1-1.0-0.8-0.8-0.91.4-1.4-0.90.9-0.9
Stereotopy head waving duration, day 30.00.00.1-0.30.10.20.10.1-0.1-0.10.1-0.00.20.20.00.3-0.3-0.0-0.1-0.0
Locomotion velocity, session 70.60.61.2-1.10.80.80.80.8-0.8-0.80.8-0.8-0.6-0.6-0.80.8-0.8-0.80.6-0.9
Locomotion distance, session 70.10.10.2-0.1-0.2-0.2-0.2-0.20.20.2-0.30.30.50.50.3-0.10.10.3-0.30.3
Stereotopy head waving bouts, day 70.00.00.2-0.20.00.00.10.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.00.0-0.4-0.3-0.5
Stereotopy head waving duration, day 70.70.81.6-1.00.80.80.90.8-0.8-0.80.8-0.9-0.9-0.9-0.90.7-0.7-1.10.7-1.3
Locomotion velocity, session 80.00.00.3-0.50.10.00.0-0.00.00.0-0.10.00.10.10.0-0.00.00.00.3-0.0
Locomotion distance, session 80.10.10.3-0.10.30.40.30.4-0.4-0.40.4-0.3-0.4-0.4-0.20.5-0.5-0.10.1-0.1
Degree of sensitization distance1.61.62.31.4-1.3-1.2-1.2-1.21.21.2-1.21.31.41.41.2-1.01.01.3-1.51.3
Degree of sensitization stereotypy0.00.00.2-0.2-0.0-0.1-0.0-0.00.00.0-0.0-0.1-0.2-0.2-0.1-0.20.2-0.3-0.2-0.4
Conditioned locomotion2.63.04.6-1.11.61.91.81.9-1.9-1.91.9-1.7-1.7-1.7-1.72.1-2.1-1.51.1-1.5
Cocaine response after cond. corrected2.52.83.6-1.81.81.61.71.6-1.6-1.61.6-1.7-1.6-1.6-1.61.5-1.5-1.91.9-1.9
Cocaine response after cond. not corrected3.63.94.3-1.82.02.02.02.0-2.0-2.02.0-2.0-2.0-2.0-1.92.0-2.0-2.11.9-2.1
Cocaine response before conditioning0.50.61.0-0.40.60.80.80.8-0.9-0.90.9-0.8-0.9-0.9-0.91.0-1.0-0.50.3-0.6
Saline control response1.01.33.0-1.41.31.01.11.0-1.0-1.01.0-1.1-1.1-1.1-1.10.8-0.8-1.11.7-1.1
Bone: connectivity density5.68.811.7-3.43.12.93.02.9-2.9-2.92.9-2.9-2.9-2.9-2.92.7-2.7-3.03.4-2.8
Bone: cortical apparent density0.50.60.8-0.70.90.90.80.8-0.8-0.80.8-0.8-0.7-0.7-0.70.7-0.7-0.80.9-0.8
Bone: cortical area0.40.60.8-0.60.70.70.80.7-0.8-0.80.8-0.8-0.9-0.9-0.70.7-0.6-0.60.8-0.8
Bone: cortical porosity1.11.21.3-1.01.11.11.11.1-1.1-1.11.1-1.1-1.1-1.1-1.11.0-1.1-1.11.1-1.1
Bone: cortical porosity1.01.11.5-1.11.11.01.11.0-1.0-1.01.0-1.1-1.0-1.0-1.10.9-0.9-1.11.2-1.1
Bone: cortical thickness0.00.00.40.6-0.1-0.1-0.0-0.0-0.0-0.00.0-0.0-0.2-0.2-0.1-0.20.20.0-0.1-0.2
Bone: cortical thickness1.41.62.0-0.71.21.31.31.3-1.3-1.31.4-1.3-1.4-1.4-1.31.4-1.3-1.01.1-1.2
Bone: cortical tissue density0.30.40.6-0.60.70.70.70.7-0.7-0.70.6-0.6-0.5-0.5-0.60.6-0.6-0.70.7-0.6
Condit. Reinf. active minus inactive responses0.30.30.8-0.2-0.4-0.5-0.5-0.50.60.6-0.60.50.90.90.5-0.60.60.6-0.50.6
Condit. Reinf. active-inactive response ratio0.20.30.5-0.2-0.3-0.5-0.5-0.50.50.5-0.60.50.70.70.4-0.60.60.5-0.30.5
Condit. Reinf. active responses0.50.61.8-1.40.90.80.80.8-0.7-0.70.7-0.8-0.4-0.4-0.80.8-0.8-0.60.9-0.6
Condit. Reinf. inactive responses1.72.02.4-1.31.51.51.51.5-1.5-1.51.4-1.4-1.3-1.3-1.41.5-1.5-1.31.5-1.3
Incentive salience index mean0.20.32.1-1.40.60.50.50.4-0.4-0.40.3-0.5-0.1-0.1-0.50.4-0.4-0.40.6-0.4
Condit. Reinf. lever presses1.41.84.8-2.21.41.31.31.3-1.2-1.21.2-1.3-1.2-1.2-1.31.1-1.1-1.41.5-1.4
Condit. Reinf. active minus inactive responses3.34.15.3-1.21.92.22.12.1-2.1-2.22.2-2.0-2.0-2.0-2.02.3-2.3-1.91.4-2.0
Condit. Reinf. active-inactive response ratio0.60.71.2-0.60.71.00.80.9-0.9-0.90.9-0.8-0.8-0.8-0.71.1-1.1-0.70.3-0.7
Condit. Reinf. active responses2.53.54.9-0.91.72.01.92.0-2.0-2.02.0-1.9-1.9-1.9-1.82.2-2.2-1.71.1-1.9
Condit. Reinf. inactive responses1.72.12.8-0.61.31.51.51.5-1.5-1.51.6-1.5-1.5-1.5-1.51.6-1.7-1.40.9-1.5
Condit. Reinf. lever presses1.52.03.1-0.61.31.61.51.5-1.6-1.61.6-1.4-1.5-1.5-1.41.7-1.7-1.30.8-1.3
Condit. Reinf. lever reinforcers received2.13.04.1-0.81.61.91.81.8-1.9-1.91.9-1.8-1.8-1.8-1.72.0-2.0-1.71.1-1.8
Conditioned reinforcement - actives0.20.20.3-0.60.60.50.50.5-0.4-0.40.4-0.4-0.4-0.4-0.40.5-0.5-0.60.4-0.3
Conditioned reinforcement - inactives1.92.12.9-1.61.61.41.41.4-1.4-1.41.4-1.4-1.4-1.4-1.51.3-1.3-1.51.7-1.3
Conditioned locomotion0.10.10.20.0-0.1-0.3-0.3-0.30.40.3-0.40.30.30.30.5-0.30.30.1-0.40.5
Patch foraging indifference point 0 sec0.20.30.5-0.1-0.4-0.6-0.5-0.60.60.6-0.60.50.50.50.6-0.60.70.5-0.50.5
Patch foraging indifference point AUC1.51.83.7-1.11.41.31.31.3-1.3-1.31.2-1.3-1.3-1.3-1.20.9-0.9-1.61.9-1.5
Delay disc. indifference point, 0s delay0.40.51.31.2-0.7-0.7-0.6-0.60.60.6-0.60.60.70.50.6-0.50.50.6-1.10.6
Delay disc. indifference point, 16s delay1.61.62.3-1.51.41.31.31.3-1.3-1.31.2-1.3-1.3-1.2-1.31.2-1.2-1.31.1-1.3
Delay disc. indifference point, 2s delay0.00.00.00.0-0.0-0.1-0.1-0.10.10.1-0.10.00.10.10.1-0.10.10.0-0.10.1
Delay disc. indifference point, 24s delay5.45.35.9-2.42.42.42.32.3-2.3-2.32.3-2.3-2.3-2.2-2.32.4-2.4-2.22.2-2.1
Delay disc. indifference point, 4s delay0.20.20.3-0.50.50.40.40.4-0.4-0.40.4-0.4-0.3-0.5-0.50.4-0.4-0.60.2-0.4
Delay disc. indifference point, 8s delay1.41.42.3-1.51.31.21.21.2-1.1-1.11.1-1.2-1.2-1.2-1.11.1-1.1-1.11.5-1.2
Indifference point function ln k0.10.10.70.4-0.3-0.1-0.2-0.10.10.1-0.10.20.20.20.10.2-0.20.5-0.90.4
Indifference point function log k0.10.10.70.4-0.3-0.1-0.2-0.10.10.1-0.10.20.20.20.10.2-0.20.5-0.90.4
Patch foraging total patch changes 0 sec0.10.20.4-0.1-0.3-0.4-0.4-0.40.40.4-0.40.40.30.30.4-0.50.60.4-0.30.3
Patch foraging total patch changes 12 sec0.60.81.30.7-0.9-1.0-0.9-0.90.90.9-0.90.90.70.70.9-1.11.10.9-0.60.8
Patch foraging total patch changes 18 sec0.10.10.3-0.40.1-0.1-0.0-0.10.10.1-0.1-0.0-0.0-0.00.1-0.40.5-0.30.5-0.2
Patch foraging total patch changes 24 sec1.31.62.01.0-1.3-1.3-1.3-1.31.31.3-1.31.31.31.31.4-1.31.41.2-0.91.3
Patch foraging total patch changes 6 sec0.00.00.3-0.20.1-0.1-0.0-0.10.10.1-0.1-0.0-0.2-0.2-0.0-0.50.6-0.20.3-0.1
Patch foraging time to switch 0 sec0.10.20.4-0.60.40.40.40.4-0.4-0.40.4-0.5-0.5-0.5-0.50.5-0.5-0.40.2-0.5
Patch foraging water rate 0 sec0.10.10.10.3-0.2-0.3-0.3-0.30.30.3-0.30.30.40.40.3-0.30.30.2-0.20.2
Patch foraging water rate 12 sec2.03.16.12.5-1.9-1.7-1.8-1.71.61.6-1.61.81.71.71.8-1.31.21.9-2.11.8
Patch foraging water rate 18 sec0.50.71.91.4-0.9-0.7-0.8-0.70.70.7-0.60.80.70.70.8-0.40.21.0-1.31.1
Patch foraging water rate 24 sec2.23.05.62.4-1.8-1.8-1.7-1.71.71.7-1.61.71.71.71.6-1.71.71.5-2.11.6
Patch foraging water rate 6 sec1.52.33.41.8-1.6-1.5-1.5-1.51.51.5-1.41.51.51.51.5-1.21.21.4-1.91.4
Seeking ratio, delayed vs. immediate footshock0.30.40.60.6-0.6-0.7-0.6-0.60.60.6-0.60.60.50.50.6-0.80.70.6-0.40.7
Distance traveled before self-admin0.10.10.3-0.10.20.30.20.2-0.2-0.20.2-0.1-0.2-0.2-0.10.5-0.5-0.10.20.1
Distance traveled after self-admin0.20.20.40.3-0.3-0.5-0.4-0.50.50.5-0.60.50.60.60.6-0.50.40.1-0.10.3
Extensor digitorum longus weight4.919.420.5-4.04.54.44.54.5-4.5-4.54.5-4.5-4.5-4.5-4.54.2-4.2-4.34.4-4.4
Bone: elastic displacement0.80.91.3-0.70.91.01.01.0-1.0-1.01.1-1.0-1.1-1.1-1.10.9-0.9-0.80.7-0.9
Bone: elastic work1.11.52.0-1.41.11.21.21.2-1.2-1.21.3-1.2-1.3-1.3-1.31.1-1.1-1.01.1-1.0
Bone: endosteal estimation0.20.41.2-1.10.50.70.60.6-0.6-0.60.6-0.5-0.5-0.5-0.30.8-0.8-0.10.8-0.1
Bone: endosteal perimeter0.10.20.8-0.90.40.40.40.4-0.4-0.40.3-0.3-0.3-0.3-0.10.4-0.4-0.10.8-0.2
Epididymis fat weight15.135.237.55.3-6.0-6.0-6.0-6.06.06.0-6.16.06.16.16.1-5.85.86.0-5.36.0
Delta time in closed arm before/after self-admin0.10.10.10.1-0.3-0.2-0.2-0.20.20.2-0.20.30.20.20.3-0.20.20.30.10.4
Delta time in open arm before/after self-admin1.00.91.8-0.81.00.81.00.9-0.9-0.90.9-1.1-0.9-0.9-1.10.4-0.6-1.31.3-1.3
Diff in mean of infusions in LGA sessions0.20.20.6-0.60.60.40.50.4-0.4-0.40.4-0.5-0.3-0.3-0.40.2-0.2-0.70.7-0.7
Delay discount exponential model param2.12.23.01.7-1.6-1.5-1.5-1.51.51.5-1.41.51.41.41.4-1.51.51.5-1.51.5
Extinction: sum of active levers before priming0.90.91.2-0.91.01.01.01.0-1.0-1.01.0-1.0-1.0-1.0-0.90.9-0.9-0.91.1-1.0
Active lever presses in extinction session 60.00.00.1-0.10.0-0.00.0-0.00.00.0-0.00.0-0.0-0.0-0.1-0.10.20.20.3-0.1
Bone: final force0.10.20.6-0.80.40.40.40.4-0.4-0.40.4-0.4-0.5-0.5-0.40.3-0.3-0.10.8-0.3
Bone: final moment0.10.20.5-0.70.40.40.40.4-0.4-0.40.4-0.4-0.5-0.5-0.40.3-0.3-0.10.7-0.3
Food consumed during 24 hour testing period0.20.20.30.10.40.40.40.4-0.5-0.50.5-0.4-0.6-0.6-0.50.5-0.4-0.40.2-0.4
Glucose0.50.81.10.9-0.8-0.8-0.9-0.90.90.9-0.90.91.11.11.0-0.80.90.8-0.60.8
Heart weight10.114.315.53.7-3.8-3.9-3.9-3.83.83.8-3.83.83.63.63.7-3.73.73.9-3.83.9
Delay discount hyperbolic model param1.81.92.41.6-1.5-1.4-1.4-1.41.41.4-1.31.41.31.31.3-1.41.41.4-1.31.4
Intermittent access intake day 1-15 change0.20.21.01.0-0.4-0.1-0.2-0.10.10.1-0.10.20.10.10.20.1-0.10.7-0.90.4
Intermittent access intake escalation0.40.41.41.2-0.6-0.4-0.5-0.40.40.4-0.40.50.30.30.5-0.20.20.9-1.10.7
Intermittent access intake escalation 21.01.02.01.4-1.0-0.9-1.0-0.90.90.9-0.81.00.80.81.1-0.70.71.3-1.41.1
Intermitt. access day 1 inactive lever presses0.10.11.3-0.50.1-0.1-0.0-0.10.10.1-0.20.10.00.00.0-0.20.20.01.10.2
Intermitt. access day 15 inactive lever presses4.14.66.1-2.32.32.12.22.1-2.1-2.12.1-2.1-2.2-2.2-2.21.9-1.9-2.02.5-2.0
Intermitt. access escalation Index0.50.41.40.1-0.5-0.7-0.6-0.70.70.7-0.70.50.50.50.4-1.21.10.3-0.30.3
Intermittent access day 1 total infusions4.75.57.5-2.62.52.32.42.3-2.3-2.22.2-2.3-2.3-2.3-2.42.0-1.9-2.72.7-2.4
Intermittent access day 15 total infusions1.41.51.9-1.21.41.31.31.3-1.3-1.31.2-1.3-1.3-1.3-1.21.2-1.2-1.21.3-1.0
Intermittent access terminal intake (last 3 days)1.41.51.9-1.41.41.21.21.2-1.2-1.21.2-1.3-1.2-1.2-1.21.1-1.1-1.31.4-1.2
Intermittent access total infusions1.71.82.3-1.41.51.41.41.4-1.3-1.31.3-1.4-1.3-1.3-1.21.3-1.3-1.51.5-1.3
Intermittent access day 1 locomotion2.62.83.5-1.61.71.61.71.6-1.6-1.61.6-1.7-1.8-1.8-1.71.4-1.4-1.91.8-1.7
Intermittent access day 15 total locomotion0.40.40.5-0.60.70.70.60.6-0.6-0.60.6-0.6-0.7-0.7-0.60.7-0.6-0.70.7-0.4
Intermittent access total locomotion0.20.30.7-0.60.60.50.50.5-0.4-0.40.4-0.5-0.5-0.5-0.40.3-0.3-0.70.8-0.4
Intermittent access standard deviation0.00.00.30.2-0.1-0.1-0.1-0.10.10.1-0.10.20.00.00.2-0.10.10.5-0.10.4
Left kidney weight0.00.10.4-0.00.20.30.20.2-0.2-0.20.3-0.2-0.1-0.1-0.10.6-0.60.00.50.0
Right kidney weight0.61.72.91.4-1.3-1.2-1.3-1.31.31.2-1.21.31.31.31.3-0.90.91.7-1.11.6
Cocaine induced anxiety0.10.10.2-0.40.20.20.20.2-0.2-0.20.2-0.3-0.2-0.2-0.30.1-0.1-0.30.4-0.2
Post-drug Anxiety0.60.61.10.0-0.7-0.8-0.8-0.80.80.8-0.90.81.01.01.0-0.90.80.5-0.40.6
Baseline Anxiety0.40.50.80.3-0.6-0.6-0.7-0.70.70.7-0.70.70.90.90.9-0.60.50.5-0.70.6
Tail length0.20.60.90.3-0.7-0.8-0.8-0.80.80.8-0.80.80.80.81.0-0.70.70.5-0.80.8
Length with tail1.45.26.91.6-2.2-2.3-2.4-2.32.42.4-2.42.42.42.42.6-2.22.22.2-1.82.4
Length without tail0.91.92.71.2-1.3-1.3-1.4-1.41.41.4-1.41.51.51.51.6-1.21.21.6-0.71.6
Times rat made contact with spout2.83.25.6-2.22.01.81.81.8-1.7-1.71.7-1.7-1.7-1.7-1.71.7-1.7-1.72.4-1.6
Lifetime Intake1.92.12.8-1.61.61.51.51.5-1.4-1.41.4-1.5-1.4-1.4-1.41.3-1.2-1.61.7-1.4
Liver weight, left2.23.54.71.8-1.9-1.7-1.9-1.81.81.8-1.82.02.12.12.0-1.51.52.1-1.62.2
Liver weight, right9.716.118.23.5-4.0-4.0-4.1-4.14.14.1-4.14.14.04.04.2-3.93.94.3-3.64.3
Locomotor activity0.10.10.6-0.70.40.20.30.2-0.2-0.20.2-0.2-0.4-0.4-0.3-0.0-0.0-0.20.8-0.2
Locomotor testing distance0.81.32.5-1.61.31.11.11.1-1.0-1.01.0-1.1-1.2-1.2-1.10.9-0.9-1.11.6-1.1
Locomotor testing rearing0.71.11.4-1.21.21.01.11.0-1.0-1.01.0-1.1-1.1-1.1-1.10.7-0.7-1.21.1-1.2
Locomotion in novel chamber1.31.61.81.3-1.3-1.3-1.2-1.31.21.2-1.21.31.31.31.3-1.31.31.3-1.11.1
Locomotion in novel chamber post-restriction1.62.02.31.0-1.3-1.4-1.4-1.41.51.5-1.51.41.51.51.4-1.41.51.3-1.11.4
Fecal boli incidents, locomotor time 10.70.71.3-1.10.90.90.90.9-0.9-0.90.8-0.9-0.5-0.6-0.60.9-0.9-0.81.0-1.0
Change in fecal boli incidents, locomotor task4.13.94.92.2-2.0-2.1-2.0-2.02.02.0-2.02.01.91.81.8-2.12.01.9-1.62.0
Time >=10cm from walls, locomotor time 10.10.10.30.60.30.30.20.3-0.3-0.30.3-0.2-0.1-0.1-0.30.3-0.4-0.10.5-0.1
Bouts of movement, locomotor time 14.24.66.1-2.22.12.22.12.2-2.2-2.22.2-2.1-2.0-2.0-2.12.4-2.5-2.01.7-2.0
Total resting periods, locomotor time 14.04.36.0-2.12.02.22.12.2-2.1-2.22.2-2.1-2.0-1.9-2.02.4-2.5-2.01.6-2.0
Rest time, locomotor task time 10.00.00.3-0.60.10.20.10.1-0.1-0.10.1-0.00.20.20.10.2-0.30.00.1-0.0
Distance moved, locomotor task time 10.70.71.40.8-0.8-1.0-0.8-0.90.90.9-0.90.80.60.60.6-1.11.20.7-1.00.7
Vertical activity count, locomotor time 10.40.41.11.1-0.7-0.6-0.6-0.60.60.6-0.60.60.30.40.5-0.50.60.8-0.70.7
Time >=10cm from walls, locomotor time 20.00.00.50.70.10.10.00.0-0.0-0.0-0.00.10.10.1-0.10.0-0.00.20.40.2
Bouts of movement, locomotor time 20.10.10.40.4-0.4-0.2-0.3-0.30.30.2-0.20.40.50.50.40.0-0.10.6-0.30.6
Total resting periods, locomotor time 20.00.10.20.2-0.20.0-0.1-0.10.10.0-0.10.20.40.40.30.2-0.30.4-0.10.3
Rest time, locomotor task time 21.71.92.5-1.51.51.51.41.5-1.4-1.41.4-1.4-1.0-1.1-1.11.5-1.6-1.61.1-1.5
Distance moved, locomotor task time 21.01.21.91.2-1.1-1.2-1.1-1.11.11.1-1.11.00.80.90.9-1.31.41.0-1.10.9
Vertical activity count, locomotor time 21.31.52.81.7-1.3-1.2-1.2-1.21.11.1-1.11.20.91.21.0-1.01.11.6-1.11.4
Light reinforcement 14.37.79.0-2.62.82.82.82.8-2.8-2.82.8-2.8-3.0-3.0-3.02.5-2.5-2.92.3-2.9
Light reinforcement 23.14.14.8-2.22.12.12.12.1-2.1-2.12.1-2.0-2.0-2.0-2.01.9-1.9-1.91.8-1.9
Bone: marrow area0.20.51.3-1.10.60.70.60.7-0.7-0.70.6-0.5-0.6-0.6-0.40.9-0.9-0.20.8-0.2
Bone: maximum diameter1.01.82.6-1.51.41.41.31.3-1.3-1.31.3-1.3-1.3-1.3-1.21.3-1.3-1.11.6-1.3
Bone: maximum force0.00.00.1-0.20.10.10.10.1-0.1-0.10.1-0.1-0.2-0.2-0.1-0.00.00.20.3-0.0
Bone: maximum moment0.00.00.1-0.20.10.10.20.1-0.2-0.20.2-0.1-0.2-0.2-0.20.1-0.10.20.3-0.0
Mean time between licks in bursts2.63.64.61.8-2.1-1.9-1.9-1.91.91.9-1.91.92.02.01.9-1.71.71.9-2.11.8
Mean num. licks in bursts0.10.20.4-0.50.40.30.40.4-0.4-0.40.4-0.4-0.4-0.4-0.40.3-0.3-0.30.6-0.3
Cd content in liver0.10.10.1-0.40.30.20.30.3-0.2-0.20.2-0.3-0.3-0.3-0.30.2-0.2-0.20.3-0.3
Co content in liver7.58.89.8-3.03.02.93.03.0-3.0-3.03.0-3.0-3.1-3.1-3.12.8-2.8-2.72.5-3.1
Cu content in liver0.30.42.6-1.60.80.50.50.5-0.4-0.40.4-0.5-0.4-0.4-0.50.3-0.3-0.41.2-0.4
Fe content in liver0.10.10.2-0.30.1-0.2-0.2-0.20.30.3-0.30.30.30.30.4-0.30.30.40.10.3
K content in liver0.40.41.00.2-0.6-0.5-0.6-0.60.60.6-0.60.70.70.70.8-0.30.31.0-0.90.8
Mg content in liver0.30.30.7-0.5-0.4-0.5-0.5-0.50.60.6-0.60.60.60.60.7-0.40.40.9-0.40.7
Mn content in liver0.20.20.5-0.20.30.50.50.5-0.5-0.60.6-0.5-0.5-0.5-0.50.7-0.7-0.20.1-0.5
Na content in liver0.20.21.5-1.20.40.40.40.4-0.4-0.40.3-0.3-0.3-0.3-0.20.5-0.4-0.10.3-0.1
Rb content in liver0.00.00.2-0.4-0.0-0.1-0.1-0.10.10.1-0.10.10.10.10.2-0.00.00.1-0.20.2
Se content in liver0.50.60.80.5-0.7-0.8-0.8-0.80.80.8-0.80.80.80.80.8-0.90.90.9-0.80.7
Sr content in liver0.10.10.30.2-0.5-0.3-0.3-0.30.30.3-0.30.40.40.40.4-0.10.10.4-0.60.6
Zn content in liver0.30.41.2-0.3-0.3-0.8-0.5-0.70.70.7-0.70.40.30.30.3-1.11.10.3-0.30.4
Bone: minimum diameter0.10.20.3-0.3-0.3-0.4-0.4-0.40.40.4-0.40.40.30.30.5-0.40.50.50.40.3
Time in familiar zone, hab. session 10.70.61.00.5-0.7-0.9-0.8-0.80.90.9-0.80.80.70.70.7-1.01.00.8-0.50.8
Time in novel zone, hab. session 10.70.61.01.0-0.8-0.8-0.8-0.80.80.8-0.80.70.90.90.7-0.80.80.6-1.00.6
Total zone transitions, hab. session 10.10.10.3-0.50.30.30.40.4-0.4-0.40.4-0.4-0.4-0.4-0.40.4-0.4-0.3-0.0-0.4
Total locomotion distance, hab. session 10.10.10.2-0.30.10.20.20.2-0.2-0.20.3-0.2-0.3-0.3-0.30.4-0.4-0.1-0.4-0.1
Locomotion velocity, hab. session 10.81.11.7-1.00.91.11.01.1-1.1-1.11.1-1.0-1.1-1.1-1.11.3-1.3-1.00.4-1.0
Time in familiar zone, hab. session 20.00.00.1-0.40.1-0.00.0-0.00.00.0-0.0-0.0-0.1-0.1-0.1-0.20.2-0.10.2-0.1
Time in novel zone, hab. session 20.50.51.01.0-0.7-0.6-0.6-0.60.60.6-0.60.70.70.70.7-0.50.50.7-0.80.7
Total zone transitions, hab. session 20.10.20.3-0.50.30.40.40.4-0.4-0.40.5-0.4-0.6-0.6-0.40.5-0.5-0.10.1-0.3
Total locomotion distance, hab. session 20.10.20.5-0.30.30.40.40.4-0.5-0.50.5-0.4-0.5-0.5-0.40.7-0.7-0.3-0.0-0.3
Locomotion velocity, hab. session 20.40.50.9-0.50.60.70.70.7-0.7-0.80.8-0.7-0.8-0.8-0.70.9-1.0-0.60.3-0.6
Novel to familiar place preference ratio0.60.62.11.4-0.9-0.8-0.7-0.70.70.7-0.60.70.60.60.6-0.70.70.6-1.20.6
Novelty place preference1.11.12.81.7-1.2-1.1-1.0-1.01.01.0-0.91.00.90.90.9-1.01.00.9-1.40.9
Time in novel zone, NPP test1.41.43.01.7-1.3-1.2-1.2-1.11.11.1-1.11.11.11.11.0-1.21.21.1-1.51.0
Total zone transitions, NPP test1.42.02.9-1.71.41.41.41.4-1.5-1.51.5-1.4-1.6-1.6-1.31.4-1.4-1.20.8-1.3
Total locomotion distance, NPP test1.52.12.8-1.41.31.51.41.5-1.5-1.51.5-1.4-1.6-1.6-1.41.7-1.7-1.20.5-1.2
Locomotion velocity, NPP test3.14.35.2-2.12.02.12.12.1-2.2-2.22.2-2.1-2.2-2.2-2.12.3-2.3-1.91.2-1.9
Intraocular pressure2.94.04.91.3-1.9-2.1-2.1-2.12.12.1-2.22.12.02.02.1-2.12.12.2-1.12.1
Delta distance traveled before/after self-admin1.41.52.31.1-1.2-1.3-1.2-1.31.31.3-1.31.21.31.31.3-1.51.51.0-0.91.0
Delta ambulatory time before/after self-admin0.30.30.70.4-0.4-0.6-0.5-0.60.60.6-0.60.50.50.50.5-0.80.70.3-0.20.3
Parametrial fat weight5.410.512.73.6-3.3-3.4-3.2-3.33.33.3-3.23.23.13.13.0-3.53.62.8-3.32.8
Pavlov. Cond. lever latency1.82.34.92.2-1.6-1.5-1.5-1.51.41.4-1.41.41.31.31.2-1.41.41.4-2.01.4
Pavlov. Cond. magazine entry latency0.00.00.4-0.60.20.10.10.1-0.1-0.10.1-0.1-0.1-0.10.00.1-0.20.00.3-0.0
Pavlov. Cond. change in total contacts0.10.10.9-1.00.30.20.20.2-0.1-0.10.1-0.1-0.1-0.10.10.2-0.20.10.50.1
Pavlov. Cond. index score0.70.92.1-1.51.01.00.90.9-0.9-0.90.8-0.8-0.8-0.8-0.70.9-0.9-0.71.2-0.7
Pavlov. Cond. latency score0.60.82.0-1.40.90.90.80.8-0.8-0.80.8-0.8-0.7-0.7-0.60.9-0.9-0.71.2-0.7
Pavlov. Cond. lever contacts1.21.43.1-1.81.21.21.21.2-1.1-1.11.1-1.1-1.0-1.0-1.01.1-1.1-1.01.5-1.1
Pavlov. Cond. magazine entry number0.30.30.60.8-0.6-0.6-0.5-0.60.60.6-0.60.50.50.50.4-0.70.70.4-0.60.4
Pavlov. Cond. intertrial magazine entries1.62.02.7-1.31.51.41.41.4-1.4-1.41.3-1.4-1.3-1.3-1.41.3-1.3-1.61.4-1.6
Pavlov. Cond. lever-magazine prob. diff.1.62.03.7-1.91.51.51.41.4-1.4-1.41.3-1.3-1.3-1.3-1.21.4-1.4-1.21.7-1.2
Pavlov. Cond. response bias1.21.52.5-1.61.31.31.21.2-1.2-1.21.2-1.2-1.1-1.1-1.11.3-1.3-1.01.4-1.1
Pavlov. Cond. lever latency1.52.02.41.2-1.4-1.5-1.4-1.51.51.5-1.51.41.41.41.4-1.51.51.4-1.11.4
Pavlov. Cond. magazine entry latency0.10.10.2-0.30.40.40.40.4-0.4-0.40.4-0.4-0.4-0.4-0.50.4-0.4-0.40.2-0.3
Pavlov. Cond. change in total contacts0.40.61.0-0.40.80.90.80.8-0.8-0.80.8-0.7-0.7-0.7-0.61.0-1.0-0.70.6-0.6
Pavlov. Cond. index score0.60.81.2-0.60.81.00.90.9-0.9-0.90.9-0.9-0.8-0.8-0.81.1-1.1-0.80.5-0.7
Pavlov. Cond. latency score0.50.71.1-0.60.80.90.80.9-0.9-0.90.9-0.8-0.8-0.8-0.81.0-1.0-0.70.5-0.7
Pavlov. Cond. lever contacts0.60.91.4-0.70.91.01.01.0-1.0-1.01.0-0.9-0.9-0.9-0.91.2-1.1-0.90.6-0.8
Pavlov. Cond. magazine entry number0.00.10.10.3-0.2-0.2-0.2-0.20.20.2-0.20.20.20.20.3-0.30.30.20.10.1
Pavlov. Cond. intertrial magazine entries2.53.33.71.8-1.9-1.9-1.9-1.91.81.8-1.81.81.81.81.7-1.91.91.7-1.81.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.30.60.70.70.7-0.7-0.70.7-0.6-0.6-0.6-0.60.9-0.9-0.60.3-0.5
Pavlov. Cond. response bias1.31.82.5-1.01.31.41.41.4-1.4-1.41.4-1.3-1.4-1.4-1.31.6-1.6-1.30.9-1.2
Time in closed arm before self-admin0.50.61.31.1-0.7-0.8-0.7-0.70.70.7-0.70.70.70.70.6-0.70.70.7-0.90.5
Time in closed arm after self-admin1.31.31.61.1-1.1-1.2-1.2-1.21.21.2-1.21.11.31.31.3-1.11.21.1-0.90.9
Time in open arm before self-admin0.10.10.4-0.60.20.40.30.3-0.3-0.30.3-0.2-0.3-0.3-0.10.6-0.5-0.10.20.0
Time in open arm after self-admin2.93.13.9-2.01.81.81.81.8-1.8-1.81.7-1.8-1.8-1.8-1.81.4-1.6-1.81.9-1.7
Bone: periosteal estimation0.40.91.6-1.30.91.00.91.0-1.0-1.01.0-0.9-1.0-1.0-0.71.0-1.0-0.51.2-0.7
Bone: periosteal perimeter0.10.20.4-0.50.40.50.50.5-0.5-0.50.5-0.5-0.5-0.5-0.30.5-0.5-0.30.7-0.5
Bone: post-yield work0.40.50.7-0.70.80.80.80.7-0.7-0.70.7-0.7-0.6-0.6-0.80.7-0.7-0.50.9-0.7
Progressive ratio test 1 active lever presses0.40.40.7-0.80.70.60.60.6-0.6-0.60.5-0.6-0.5-0.5-0.60.5-0.5-0.70.8-0.5
Progressive ratio test 1 breakpoint0.30.30.8-0.80.70.60.60.6-0.5-0.50.5-0.5-0.5-0.5-0.60.5-0.4-0.60.9-0.4
Progressive ratio test 1 inactive lever presses1.01.12.3-1.31.21.01.11.0-1.0-1.00.9-1.0-1.1-1.1-1.20.7-0.7-1.21.5-0.9
Progressive ratio test 2 active lever presses0.00.00.1-0.20.20.0-0.0-0.00.10.1-0.10.10.30.30.20.2-0.0-0.20.20.1
Progressive ratio test 2 breakpoint0.00.00.1-0.30.20.10.00.00.00.0-0.1-0.00.20.20.10.3-0.1-0.20.30.1
Progressive ratio test 2 inactive lever presses0.60.71.0-1.01.00.80.80.8-0.8-0.80.7-0.8-0.7-0.7-0.90.8-0.6-1.01.0-0.7
Incentive Sensitization - Responses0.10.10.30.4-0.2-0.2-0.3-0.20.20.2-0.20.20.40.40.30.1-0.00.2-0.50.2
Incentive Sensitization - Breakpoint0.20.20.40.5-0.4-0.4-0.4-0.40.40.4-0.40.40.60.60.5-0.10.20.4-0.60.4
Sum of active levers in priming session hrs 5-61.21.21.6-1.31.11.11.11.1-1.1-1.11.1-1.1-1.1-1.1-1.01.0-1.1-1.01.1-1.1
Progressive ratio0.70.81.01.0-0.9-0.8-0.9-0.90.90.9-0.90.91.01.01.0-0.90.91.0-0.70.8
Food seeking constrained by brief footshock2.63.24.4-1.81.91.81.81.8-1.8-1.81.7-1.8-1.8-1.8-1.81.7-1.7-1.82.1-1.7
Seeking ratio, punishment vs. effort1.82.22.6-1.41.51.51.51.5-1.5-1.51.5-1.5-1.6-1.6-1.61.5-1.5-1.51.4-1.3
Retroperitoneal fat weight21.670.974.08.2-8.5-8.6-8.6-8.68.68.6-8.58.58.48.48.4-8.68.48.1-7.98.3
Reaction time number correct0.50.81.3-0.30.91.00.91.0-0.9-0.90.9-0.9-0.8-0.8-0.81.1-1.1-0.80.7-0.8
Reaction time mean minus median0.10.10.3-0.50.30.20.30.2-0.2-0.20.2-0.3-0.5-0.5-0.40.1-0.2-0.40.5-0.3
Reaction time mean minus median AUC0.00.00.1-0.00.1-0.00.10.0-0.0-0.00.1-0.1-0.3-0.3-0.2-0.0-0.1-0.20.2-0.1
Reaction time num false alarms0.30.40.5-0.60.70.70.70.7-0.7-0.70.7-0.7-0.6-0.6-0.70.6-0.6-0.60.7-0.7
Reaction time num false alarms AUC0.60.91.0-0.91.01.01.01.0-1.0-1.01.0-1.0-0.9-0.9-0.90.9-0.9-0.91.0-0.9
Reaction time trials correct on left0.50.81.3-0.30.91.00.91.0-0.9-0.90.9-0.9-0.8-0.8-0.81.1-1.1-0.80.7-0.8
Reaction time trials on left0.60.91.4-0.30.91.00.91.0-1.0-1.01.0-0.9-0.9-0.9-0.81.2-1.2-0.80.7-0.9
Reaction time mean0.50.61.30.0-0.5-0.9-0.8-0.90.91.0-1.00.70.90.90.7-1.11.10.40.20.5
Reaction time mean AUC0.40.51.1-0.1-0.4-0.8-0.7-0.80.80.8-0.90.60.70.70.6-1.01.00.30.30.4
Median of all reaction times0.50.71.6-0.0-0.5-1.0-0.8-0.91.01.0-1.00.81.01.00.8-1.21.20.40.30.5
Reaction time omissions0.20.20.4-0.50.40.40.50.4-0.4-0.40.4-0.5-0.5-0.5-0.60.3-0.3-0.50.5-0.6
Reaction time false alarm rate0.10.10.3-0.60.30.30.30.3-0.3-0.30.3-0.3-0.3-0.3-0.30.1-0.1-0.30.4-0.3
Reaction time premature initiation rate0.20.20.30.3-0.5-0.4-0.5-0.50.40.4-0.40.50.50.50.4-0.40.40.5-0.40.6
Reaction time premature initiations0.00.00.10.20.00.20.10.1-0.1-0.10.1-0.0-0.0-0.0-0.10.3-0.30.1-0.10.1
Std. dev. reaction times0.10.20.40.1-0.3-0.6-0.5-0.50.50.5-0.50.40.40.40.4-0.60.60.2-0.10.3
Reaction time trials completed0.60.91.4-0.30.91.00.91.0-1.0-1.01.0-0.9-0.9-0.9-0.81.2-1.2-0.80.7-0.9
Reaction time trials AUC0.81.11.8-0.51.11.21.11.1-1.1-1.11.1-1.1-1.0-1.0-1.01.3-1.3-1.00.9-1.0
Run reversals in cocaine runway, females0.00.00.10.3-0.10.1-0.00.0-0.0-0.10.00.00.10.10.20.3-0.20.0-0.30.0
Run reversals in cocaine runway, males0.60.60.9-0.60.70.70.70.8-0.8-0.80.8-0.8-0.9-0.9-0.60.7-0.7-0.50.7-0.7
Latency to leave start box in cocaine runway0.40.40.9-0.70.70.60.60.6-0.6-0.60.6-0.7-0.7-0.7-0.90.5-0.6-0.90.5-0.6
Latency to leave start box in cocaine runway, F0.60.61.2-1.10.90.80.80.8-0.7-0.70.7-0.8-0.8-0.8-0.90.5-0.7-0.90.7-0.8
Latency to leave start box in cocaine runway, M0.10.10.20.20.20.30.20.2-0.2-0.20.2-0.2-0.2-0.2-0.30.4-0.4-0.4-0.1-0.1
Std. dev. time between licks in bursts0.00.00.1-0.1-0.1-0.2-0.2-0.20.20.2-0.20.20.20.20.1-0.30.3-0.1-0.10.1
Total sessions with >9 infusions0.60.71.0-0.80.90.80.80.8-0.8-0.80.8-0.8-1.0-1.0-1.00.5-0.5-0.80.8-0.7
Short access day 1 total inactive lever presses3.33.65.9-2.42.11.81.91.8-1.8-1.81.8-1.9-1.9-1.9-2.11.3-1.3-1.92.4-1.7
Short access day 10 total inactive lever presses0.30.40.6-0.50.60.60.60.6-0.6-0.60.6-0.5-0.8-0.8-0.70.5-0.4-0.50.8-0.4
Short access day 1 total infusions1.92.03.3-1.81.61.31.41.3-1.3-1.31.3-1.4-1.5-1.5-1.60.7-0.6-1.61.8-1.4
Short access day 10 total infusions3.33.74.7-2.12.12.02.01.9-1.9-1.91.8-1.9-1.7-1.7-1.91.8-1.7-2.12.2-1.9
Short access total infusions1.21.32.2-1.41.31.11.21.1-1.1-1.11.1-1.1-1.1-1.1-1.20.8-0.7-1.31.5-1.1
Short access day 1 locomotion4.24.55.3-2.22.22.12.22.1-2.1-2.12.1-2.2-2.3-2.3-2.21.9-1.8-2.11.9-2.1
Short access day 10 total locomotion1.11.21.6-1.31.21.01.11.1-1.0-1.01.0-1.1-1.2-1.2-1.00.8-1.0-1.21.3-1.0
Short access total locomotion0.30.30.6-0.80.70.50.60.5-0.5-0.50.5-0.6-0.7-0.7-0.50.2-0.2-0.70.7-0.6
One hour access (0.3 mA shock)1.11.32.0-1.41.31.21.21.2-1.1-1.11.1-1.1-1.1-1.1-1.01.2-1.2-1.01.2-0.9
Compulsive drug intake0.20.20.40.6-0.6-0.4-0.5-0.50.40.4-0.40.60.40.40.4-0.50.40.6-0.60.5
One hour access (shock baseline)1.31.52.3-1.51.41.31.21.2-1.2-1.21.1-1.2-1.1-1.1-1.01.2-1.2-1.31.3-1.1
Social response proportion0.30.30.90.7-0.6-0.7-0.6-0.60.60.6-0.60.50.40.40.3-0.80.90.4-0.40.3
Social responses0.00.00.20.20.0-0.3-0.1-0.20.20.2-0.20.0-0.1-0.1-0.1-0.40.4-0.10.2-0.2
Social time0.50.71.31.0-0.8-1.0-0.9-0.90.90.9-0.90.70.60.60.6-1.21.10.6-0.20.6
Soleus weight5.716.718.2-3.74.24.14.14.1-4.1-4.14.1-4.1-4.3-4.3-4.13.8-3.8-4.04.3-4.0
Bone: stiffness0.00.10.20.3-0.2-0.2-0.3-0.30.30.3-0.30.30.30.30.4-0.20.20.4-0.00.3
Tibialis anterior weight4.214.516.0-3.43.83.83.93.8-3.9-3.83.9-3.9-4.0-4.0-4.03.5-3.5-3.93.5-3.9
Time to tail flick, vehicle, before self-admin1.71.72.01.3-1.3-1.3-1.3-1.31.31.3-1.31.21.41.41.4-1.31.41.3-1.31.1
Time to tail flick, vehicle, after self-admin3.13.33.81.4-1.7-1.9-1.9-1.91.91.9-1.91.81.81.81.6-1.92.02.0-1.61.9
Time to tail flick, test, before self-admin0.60.60.8-0.80.80.70.80.8-0.8-0.70.8-0.8-0.8-0.8-0.90.7-0.6-0.60.9-0.8
Time to tail flick, test, after self-admin0.10.10.10.3-0.3-0.2-0.3-0.30.30.3-0.30.30.40.40.4-0.00.00.40.00.3
Delta time to tail flick, vehicle, before/after SA0.10.10.30.0-0.2-0.3-0.3-0.30.20.2-0.20.30.20.2-0.1-0.10.10.6-0.10.6
Delta time to tail flick, test, before/after SA0.20.20.6-0.30.30.50.40.5-0.5-0.50.5-0.4-0.3-0.3-0.20.8-0.8-0.30.3-0.2
Tibia length2.67.38.42.0-2.6-2.8-2.8-2.82.92.9-2.92.82.82.82.9-2.92.92.7-2.02.6
Ambulatory time before self-admin0.20.20.6-0.30.50.60.50.5-0.5-0.50.5-0.4-0.4-0.4-0.30.8-0.8-0.40.2-0.2
Ambulatory time after self-admin0.10.10.20.3-0.2-0.4-0.3-0.40.40.4-0.40.30.40.40.4-0.50.30.00.00.2
Bone: tissue strength0.30.30.60.5-0.5-0.6-0.5-0.60.60.6-0.60.50.60.60.4-0.80.80.4-0.50.3
Total heroin consumption2.63.13.9-1.51.81.81.81.8-1.8-1.81.8-1.8-1.8-1.8-2.01.6-1.8-1.61.8-1.7
Bone: trabecular number4.87.510.4-3.22.92.72.72.7-2.6-2.62.6-2.7-2.7-2.7-2.72.4-2.3-2.93.2-2.7
Bone: trabecular spacing2.02.74.21.3-1.6-1.7-1.6-1.71.61.7-1.61.61.51.51.5-1.71.71.6-2.01.6
Bone: trabecular thickness0.60.71.1-0.90.80.80.80.8-0.8-0.80.8-0.9-0.8-0.8-0.80.8-0.8-0.91.0-0.9
Bone: trabecular tissue density0.00.10.2-0.10.20.30.20.3-0.2-0.20.2-0.20.00.0-0.00.4-0.5-0.20.3-0.1
Water consumed over 24 hours1.11.31.7-1.21.21.31.21.2-1.2-1.21.2-1.1-1.1-1.1-1.11.3-1.3-1.01.2-0.9
Number of responses in last shaping day0.00.00.1-0.30.20.20.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.3-0.30.10.30.1