Hub : Genes

Tmtc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tmtc2 0.1 0.06 2.1e-05 0.04 0.05 0.06 0.06 3.1e-05 1.5e-06 9.8e-07 1.3e-06
2 NAcc alternative polyA XM_039078703.2 0.06 0.04 3.2e-04 0.04 0.02 0.03 0.03 1.4e-06 1.4e-04 1.5e-05 5.2e-06
3 NAcc alternative polyA XM_039078706.2 0.04 0.03 4.4e-03 0.03 0.01 0.02 0.03 2.3e-05 2.5e-03 2.0e-04 6.7e-05
4 NAcc gene expression Tmtc2 0.17 0.06 0.0e+00 0.17 0.17 0.17 0.18 2.8e-25 4.2e-25 1.7e-25 5.6e-26
5 Adipose gene expression Tmtc2 0.13 0.06 2.2e-09 0.07 0.08 0.08 0.09 2.1e-08 5.8e-09 3.9e-09 1.6e-10
6 Liver alternative polyA XM_039078703.2 0.03 0.02 5.2e-03 0.02 0.01 0 0.01 2.3e-03 1.5e-02 1.2e-01 1.7e-02
7 Liver gene expression Tmtc2 0.06 0.03 3.0e-05 0.03 0.04 0.03 0.03 3.0e-04 7.7e-05 1.8e-04 2.6e-04
8 Brain gene expression Tmtc2 0.12 0.05 4.2e-10 0.1 0.11 0.11 0.1 6.4e-10 4.2e-10 4.7e-10 7.7e-10
9 BLA gene expression Tmtc2 0.17 0.09 1.9e-05 0.04 0.07 0.07 0.09 2.0e-03 1.1e-04 1.7e-04 2.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.41.50.6-0.80.81.2-0.40.3-0.40.20.1
Area under the delay curve2.32.75.32.1-1.71.71.51.2-1.62.31.40.9
BMI with tail0.72.57.1-1.82.3-2.3-2.7-0.30.40.2-1.3-0.1
BMI without tail0.10.41.10.00.4-0.4-0.71.00.10.40.61.1
Body weight0.10.51.20.40.6-0.6-0.51.0-0.30.80.71.1
Weight adjusted by age0.10.20.4-0.50.4-0.4-0.5-0.2-0.1-0.6-0.50.0
Bone surface0.30.51.20.5-0.20.20.6-1.1-0.90.8-0.7-0.8
Bone volume0.10.20.70.5-0.20.20.7-0.8-0.30.2-0.5-0.4
Breakpoint value in progressive ratio session2.42.84.90.8-1.61.61.52.01.7-1.02.22.0
Number of licking bursts0.40.71.11.0-0.90.90.70.7-0.60.90.90.6
Context. condit. distance diff. score2.53.09.22.7-1.91.93.0-0.1-1.01.11.0-0.3
Locomotion velocity, session 11.21.33.8-0.70.7-0.7-1.11.71.1-0.40.82.0
Locomotion distance, session 11.01.32.8-0.21.3-1.3-1.41.6-0.20.70.51.7
Locomotion velocity, session 20.60.71.7-0.20.9-0.9-1.10.9-1.11.3-0.10.5
Locomotion distance, session 21.52.15.3-1.02.0-2.0-2.31.4-0.40.8-0.21.1
Locomotion velocity, session 31.11.32.21.4-0.90.91.21.5-0.20.31.51.3
Locomotion distance, session 32.93.16.82.6-1.31.31.92.0-1.31.52.11.3
Stereotopy head waving bouts, day 30.00.00.30.3-0.00.00.10.3-0.00.10.00.5
Stereotopy head waving duration, day 30.40.41.0-0.90.8-0.8-1.0-0.20.3-0.4-0.80.0
Locomotion velocity, session 71.11.32.31.5-1.11.11.11.1-0.70.81.31.2
Locomotion distance, session 71.01.32.21.5-1.41.41.10.4-1.31.10.80.3
Stereotopy head waving bouts, day 71.21.42.41.6-0.70.71.01.5-0.41.41.41.4
Stereotopy head waving duration, day 71.11.32.51.6-0.80.81.21.3-0.31.21.41.3
Locomotion velocity, session 80.30.31.0-0.70.5-0.5-0.3-0.01.0-1.0-0.20.3
Locomotion distance, session 80.81.12.71.6-0.90.91.51.0-0.30.91.10.7
Degree of sensitization distance0.80.82.3-1.0-0.60.6-0.5-1.50.0-0.3-1.2-1.1
Degree of sensitization stereotypy1.01.12.31.3-0.20.20.61.3-0.61.51.21.3
Conditioned locomotion0.70.81.5-0.90.6-0.6-0.4-1.21.0-0.6-1.0-1.1
Cocaine response after cond. corrected0.50.63.00.7-0.20.20.2-0.2-1.11.70.1-0.4
Cocaine response after cond. not corrected1.01.23.91.2-1.01.00.6-0.0-1.72.00.5-0.2
Cocaine response before conditioning1.01.23.11.0-1.81.80.80.5-1.00.30.90.7
Saline control response0.40.61.40.1-0.80.8-0.00.90.6-0.11.01.2
Bone: connectivity density0.40.61.30.9-1.11.11.2-0.5-0.50.4-0.0-0.1
Bone: cortical apparent density3.95.38.32.6-2.82.82.02.1-0.81.52.92.3
Bone: cortical area1.01.53.21.8-0.70.71.11.1-1.51.81.00.6
Bone: cortical porosity1.51.62.7-1.60.9-0.9-0.8-1.40.9-1.6-1.5-1.3
Bone: cortical porosity1.71.93.9-2.01.1-1.1-1.2-1.01.4-2.0-1.3-0.9
Bone: cortical thickness1.93.26.32.5-2.02.02.11.2-1.51.81.50.7
Bone: cortical thickness2.02.34.72.2-1.51.52.01.4-0.70.71.81.1
Bone: cortical tissue density3.64.97.82.5-2.72.71.92.1-0.61.42.82.3
Condit. Reinf. active minus inactive responses0.40.51.6-0.70.4-0.4-0.0-0.71.3-1.2-0.40.1
Condit. Reinf. active-inactive response ratio0.20.20.6-0.2-0.10.10.4-0.70.7-0.8-0.1-0.2
Condit. Reinf. active responses0.20.31.0-0.50.2-0.2-0.2-0.21.0-1.0-0.30.3
Condit. Reinf. inactive responses0.40.52.00.3-0.50.5-0.11.40.10.20.71.2
Incentive salience index mean1.11.32.6-1.51.0-1.0-0.8-1.11.5-1.6-1.0-0.3
Condit. Reinf. lever presses1.62.34.5-2.11.7-1.7-1.8-1.11.1-1.3-1.6-0.6
Condit. Reinf. active minus inactive responses1.11.44.70.8-0.20.2-0.02.2-1.00.61.71.7
Condit. Reinf. active-inactive response ratio1.01.13.70.5-0.30.3-0.01.9-0.30.21.61.8
Condit. Reinf. active responses0.40.52.00.30.2-0.2-0.31.4-0.90.30.90.9
Condit. Reinf. inactive responses0.10.10.40.30.1-0.10.1-0.2-0.70.4-0.0-0.4
Condit. Reinf. lever presses0.10.10.80.30.2-0.2-0.00.3-0.90.10.30.1
Condit. Reinf. lever reinforcers received0.50.72.10.40.0-0.0-0.41.4-1.20.71.00.9
Conditioned reinforcement - actives1.11.95.9-0.22.4-2.4-0.7-1.2-0.90.6-1.1-1.0
Conditioned reinforcement - inactives0.40.61.20.40.9-0.90.4-1.1-0.80.3-0.7-0.9
Conditioned locomotion0.20.30.80.30.9-0.9-0.30.2-0.40.3-0.10.5
Patch foraging indifference point 0 sec0.61.03.8-0.5-0.40.40.4-1.90.2-0.7-1.3-1.7
Patch foraging indifference point AUC0.50.72.60.3-0.40.40.6-1.6-0.40.2-0.8-1.4
Delay disc. indifference point, 0s delay0.90.92.50.5-0.40.40.4-0.9-1.21.6-0.9-1.5
Delay disc. indifference point, 16s delay3.13.57.32.4-1.51.51.31.8-1.62.71.91.5
Delay disc. indifference point, 2s delay0.20.20.60.4-0.70.70.80.1-0.00.30.4-0.1
Delay disc. indifference point, 24s delay2.62.96.52.4-0.80.81.11.6-1.82.61.71.7
Delay disc. indifference point, 4s delay0.20.20.50.1-0.60.60.5-0.7-0.10.1-0.3-0.4
Delay disc. indifference point, 8s delay2.12.55.52.0-1.61.61.21.0-1.72.31.30.7
Indifference point function ln k0.61.03.60.40.5-0.5-0.11.9-0.00.21.41.8
Indifference point function log k0.61.03.60.40.5-0.5-0.11.9-0.00.21.41.8
Patch foraging total patch changes 0 sec0.40.82.9-0.2-0.60.60.6-1.70.2-0.6-1.0-1.4
Patch foraging total patch changes 12 sec1.21.63.80.4-1.31.30.9-2.0-1.00.2-1.1-2.0
Patch foraging total patch changes 18 sec0.81.23.70.1-1.21.20.9-1.90.2-0.4-0.8-1.5
Patch foraging total patch changes 24 sec0.20.31.10.3-0.20.20.0-1.0-1.00.6-0.6-0.5
Patch foraging total patch changes 6 sec0.60.92.80.1-0.70.70.6-1.6-0.5-0.0-0.8-1.7
Patch foraging time to switch 0 sec0.00.10.2-0.4-0.30.3-0.3-0.2-0.00.0-0.3-0.4
Patch foraging water rate 0 sec0.20.51.21.1-0.70.71.00.4-0.60.60.70.4
Patch foraging water rate 12 sec0.61.33.50.20.9-0.9-0.81.9-0.60.90.91.8
Patch foraging water rate 18 sec0.60.93.90.00.1-0.1-0.41.80.1-0.21.02.0
Patch foraging water rate 24 sec2.43.47.21.6-1.41.40.12.7-1.82.12.12.3
Patch foraging water rate 6 sec1.21.75.70.30.9-0.9-0.62.4-0.20.21.62.3
Seeking ratio, delayed vs. immediate footshock0.60.71.41.10.5-0.50.40.8-1.21.20.90.3
Distance traveled before self-admin0.91.12.21.3-1.31.30.70.6-1.51.30.60.5
Distance traveled after self-admin0.10.20.4-0.20.3-0.3-0.4-0.4-0.40.2-0.6-0.4
Extensor digitorum longus weight0.31.22.9-1.60.9-0.9-1.1-0.11.7-1.6-0.60.1
Bone: elastic displacement0.30.31.40.3-0.20.20.80.10.5-1.20.30.3
Bone: elastic work0.40.51.40.60.2-0.20.31.1-0.4-0.20.91.2
Bone: endosteal estimation0.51.02.9-1.01.7-1.7-1.2-0.30.4-0.4-0.7-0.5
Bone: endosteal perimeter0.20.41.3-0.21.1-1.1-0.4-0.3-0.10.3-0.3-0.4
Epididymis fat weight0.62.14.02.0-1.71.71.40.1-1.91.80.9-0.2
Delta time in closed arm before/after self-admin0.80.72.6-0.5-0.60.60.6-0.81.6-1.3-0.3-0.2
Delta time in open arm before/after self-admin0.40.41.00.2-1.01.00.8-0.1-0.0-0.80.1-0.4
Diff in mean of infusions in LGA sessions2.73.26.51.2-1.31.31.62.51.7-0.72.52.5
Delay discount exponential model param2.22.54.3-2.01.6-1.6-1.4-1.31.4-2.1-1.5-1.1
Extinction: sum of active levers before priming1.01.12.4-0.81.1-1.1-0.0-1.50.9-1.4-1.0-0.9
Active lever presses in extinction session 60.50.52.30.3-0.20.21.10.00.8-1.50.60.2
Bone: final force0.61.02.21.5-0.90.91.1-0.2-1.41.20.3-0.6
Bone: final moment0.60.92.21.4-0.90.90.90.0-1.51.30.4-0.3
Food consumed during 24 hour testing period0.10.20.3-0.50.6-0.6-0.5-0.00.1-0.5-0.30.0
Glucose0.30.52.10.50.3-0.3-0.50.1-1.41.4-0.2-0.3
Heart weight0.20.30.90.5-0.30.30.30.90.00.50.60.8
Delay discount hyperbolic model param1.92.13.1-1.81.6-1.6-1.4-1.21.0-1.6-1.4-1.0
Intermittent access intake day 1-15 change0.00.10.3-0.1-0.20.2-0.30.1-0.60.50.0-0.4
Intermittent access intake escalation0.10.20.50.1-0.50.50.1-0.3-0.70.2-0.1-0.7
Intermittent access intake escalation 20.20.21.0-0.60.3-0.3-1.00.3-0.50.0-0.1-0.0
Intermitt. access day 1 inactive lever presses0.10.51.10.0-1.01.00.6-0.70.1-0.3-0.3-1.0
Intermitt. access day 15 inactive lever presses0.10.30.9-0.90.0-0.0-0.7-0.60.0-0.3-0.7-0.6
Intermitt. access escalation Index0.20.20.6-0.30.5-0.5-0.50.50.4-0.40.20.8
Intermittent access day 1 total infusions0.60.92.71.20.6-0.60.5-0.6-1.61.6-0.3-0.5
Intermittent access day 15 total infusions0.71.03.60.70.2-0.20.2-1.0-1.91.3-0.5-1.3
Intermittent access terminal intake (last 3 days)0.60.71.70.00.8-0.8-0.5-0.8-1.31.0-0.8-1.0
Intermittent access total infusions0.80.91.80.31.1-1.1-0.3-1.0-1.31.0-0.8-1.0
Intermittent access day 1 locomotion0.91.23.21.8-0.10.11.3-0.6-1.71.50.1-0.5
Intermittent access day 15 total locomotion0.81.43.31.8-1.31.31.8-0.1-1.01.30.6-0.3
Intermittent access total locomotion0.81.02.11.4-0.40.41.2-0.8-1.41.3-0.1-0.8
Intermittent access standard deviation0.61.23.2-1.21.7-1.7-1.80.2-0.20.1-0.70.0
Left kidney weight0.41.96.50.40.2-0.2-0.52.50.50.31.92.5
Right kidney weight0.62.85.12.0-1.51.51.32.2-0.41.32.32.0
Cocaine induced anxiety1.52.15.1-0.71.1-1.1-0.9-2.1-1.30.7-2.0-2.3
Post-drug Anxiety2.32.44.8-0.81.3-1.3-1.3-2.0-1.31.2-2.2-2.1
Baseline Anxiety0.30.30.90.5-0.10.10.00.8-0.20.90.51.0
Tail length1.35.210.53.2-2.32.32.72.0-1.41.52.81.8
Length with tail0.83.57.92.8-1.81.82.21.1-1.81.61.91.0
Length without tail0.10.20.60.60.1-0.10.30.0-0.80.60.30.0
Times rat made contact with spout1.21.42.7-1.61.3-1.3-1.30.21.6-1.3-0.40.7
Lifetime Intake0.91.12.90.70.8-0.8-0.0-1.0-1.71.5-0.8-1.1
Liver weight, left1.62.65.0-1.32.2-2.2-1.7-1.6-0.40.3-1.9-1.5
Liver weight, right0.61.13.3-1.21.2-1.2-1.81.00.8-0.20.00.7
Locomotor activity0.20.30.80.5-0.60.60.50.60.40.20.60.9
Locomotor testing distance0.30.50.80.7-0.90.90.60.70.20.50.80.7
Locomotor testing rearing0.30.71.90.8-1.41.41.1-0.00.00.00.50.2
Locomotion in novel chamber4.05.113.23.6-1.81.83.11.5-1.72.02.31.5
Locomotion in novel chamber post-restriction0.10.21.00.70.1-0.11.00.10.0-0.20.40.0
Fecal boli incidents, locomotor time 10.20.31.6-0.4-0.00.00.4-0.20.8-1.30.30.0
Change in fecal boli incidents, locomotor task1.21.22.21.5-1.21.21.41.0-0.00.71.20.7
Time >=10cm from walls, locomotor time 10.10.10.2-0.40.1-0.1-0.4-0.3-0.2-0.1-0.40.2
Bouts of movement, locomotor time 11.11.32.71.0-1.31.31.11.30.60.31.71.2
Total resting periods, locomotor time 10.50.51.00.3-0.90.90.50.80.7-0.01.00.6
Rest time, locomotor task time 10.30.41.2-0.70.4-0.4-0.6-0.41.1-0.8-0.3-0.6
Distance moved, locomotor task time 10.10.20.60.40.3-0.30.30.2-0.80.40.20.4
Vertical activity count, locomotor time 10.10.30.90.70.0-0.00.90.4-0.20.20.70.5
Time >=10cm from walls, locomotor time 20.20.20.6-0.60.8-0.8-0.30.00.5-0.4-0.3-0.0
Bouts of movement, locomotor time 20.10.10.6-0.30.1-0.1-0.40.80.2-0.20.20.5
Total resting periods, locomotor time 20.00.10.2-0.40.1-0.1-0.40.50.3-0.20.00.2
Rest time, locomotor task time 20.30.42.2-0.3-0.70.70.4-0.41.5-0.70.0-0.1
Distance moved, locomotor task time 20.60.72.70.20.9-0.9-0.70.5-1.61.2-0.30.1
Vertical activity count, locomotor time 20.60.92.91.20.6-0.60.51.0-1.71.00.80.3
Light reinforcement 10.51.22.9-1.70.7-0.7-1.6-1.00.7-0.7-1.5-0.7
Light reinforcement 20.60.92.3-1.40.7-0.7-0.8-0.21.5-1.5-0.60.4
Bone: marrow area0.40.92.5-1.01.6-1.6-1.1-0.30.3-0.3-0.7-0.5
Bone: maximum diameter0.20.51.1-0.01.1-1.1-0.60.2-0.51.0-0.3-0.2
Bone: maximum force0.51.02.51.6-0.60.61.10.2-1.41.40.5-0.1
Bone: maximum moment0.50.92.41.4-0.60.60.80.4-1.41.50.50.1
Mean time between licks in bursts1.22.85.52.0-1.11.11.32.2-1.30.92.32.1
Mean num. licks in bursts0.91.32.7-1.61.3-1.3-1.2-0.31.5-1.3-0.80.1
Cd content in liver0.20.20.4-0.30.5-0.5-0.70.4-0.40.0-0.20.6
Co content in liver0.40.42.30.4-0.10.1-0.10.2-1.21.5-0.10.0
Cu content in liver1.01.22.7-0.51.4-1.4-1.61.2-0.50.80.31.0
Fe content in liver0.91.01.9-1.11.4-1.4-1.0-0.7-0.1-0.4-1.1-1.2
K content in liver3.83.66.2-2.32.3-2.3-2.30.62.5-1.6-0.41.1
Mg content in liver1.21.23.2-1.51.5-1.5-1.8-0.20.6-0.3-0.90.1
Mn content in liver0.20.20.8-0.40.3-0.3-0.90.4-0.10.1-0.20.3
Na content in liver1.41.54.4-1.22.1-2.1-1.5-0.10.8-0.1-0.7-0.3
Rb content in liver0.10.10.4-0.40.0-0.0-0.3-0.40.30.2-0.6-0.2
Se content in liver0.60.71.5-0.11.0-1.0-0.7-0.5-1.21.0-0.7-0.9
Sr content in liver0.30.30.8-0.10.9-0.9-0.50.4-0.30.2-0.00.6
Zn content in liver0.91.02.8-1.21.4-1.4-1.70.70.1-0.3-0.10.6
Bone: minimum diameter0.40.73.11.10.3-0.30.30.3-1.41.80.4-0.0
Time in familiar zone, hab. session 11.71.64.3-1.41.3-1.3-0.70.22.0-2.10.10.7
Time in novel zone, hab. session 11.71.73.31.6-1.51.51.2-0.3-1.81.80.0-0.7
Total zone transitions, hab. session 11.21.63.2-0.81.8-1.8-1.21.60.7-0.80.61.5
Total locomotion distance, hab. session 11.21.73.4-0.71.8-1.8-0.91.21.0-1.00.71.7
Locomotion velocity, hab. session 11.21.63.3-0.91.8-1.8-1.31.20.9-0.80.51.6
Time in familiar zone, hab. session 20.70.72.4-0.2-0.40.4-0.61.50.50.21.11.4
Time in novel zone, hab. session 20.70.82.3-0.10.6-0.60.1-1.5-0.5-0.0-1.3-1.3
Total zone transitions, hab. session 20.60.71.8-0.31.3-1.3-1.20.7-0.50.1-0.00.7
Total locomotion distance, hab. session 20.60.71.7-0.31.3-1.3-0.80.70.2-0.50.31.2
Locomotion velocity, hab. session 20.50.61.6-0.21.3-1.3-0.80.50.1-0.50.31.1
Novel to familiar place preference ratio0.40.51.8-0.2-0.10.10.1-1.4-0.40.1-0.8-1.2
Novelty place preference0.30.31.4-0.2-0.20.20.2-1.2-0.1-0.1-0.6-1.0
Time in novel zone, NPP test0.30.31.0-0.1-0.40.40.2-1.0-0.20.1-0.4-0.9
Total zone transitions, NPP test0.60.92.1-1.01.4-1.4-1.40.50.6-0.2-0.20.3
Total locomotion distance, NPP test1.11.53.1-1.11.8-1.8-1.61.00.9-0.70.31.2
Locomotion velocity, NPP test1.01.42.6-1.21.6-1.6-1.50.81.1-1.00.21.1
Intraocular pressure0.81.12.51.6-0.80.81.2-0.3-1.41.60.1-0.6
Delta distance traveled before/after self-admin0.50.51.6-1.00.6-0.6-0.5-0.21.2-1.1-0.4-0.1
Delta ambulatory time before/after self-admin1.92.33.8-1.92.0-2.0-1.5-1.21.1-1.0-1.5-1.1
Parametrial fat weight0.20.51.00.01.0-1.00.20.20.9-0.90.40.5
Pavlov. Cond. lever latency0.10.10.20.10.2-0.2-0.2-0.2-0.50.4-0.2-0.5
Pavlov. Cond. magazine entry latency0.50.61.40.8-1.21.21.10.60.20.40.70.4
Pavlov. Cond. change in total contacts0.10.10.30.2-0.50.50.6-0.20.50.00.0-0.3
Pavlov. Cond. index score0.70.91.30.9-1.01.01.01.10.30.41.21.1
Pavlov. Cond. latency score0.40.60.90.7-0.80.80.80.90.40.10.90.9
Pavlov. Cond. lever contacts0.10.10.3-0.0-0.40.40.20.30.5-0.40.20.5
Pavlov. Cond. magazine entry number1.41.72.6-1.41.6-1.6-1.5-1.4-0.2-0.7-1.5-1.2
Pavlov. Cond. intertrial magazine entries0.30.31.7-0.1-0.20.20.5-0.60.7-1.30.2-0.4
Pavlov. Cond. lever-magazine prob. diff.0.50.60.90.8-0.80.80.90.90.20.50.90.9
Pavlov. Cond. response bias0.50.61.10.9-1.01.01.00.70.10.50.90.7
Pavlov. Cond. lever latency0.30.41.3-0.80.5-0.5-0.6-0.21.2-0.8-0.4-0.1
Pavlov. Cond. magazine entry latency1.21.42.41.4-1.51.51.00.9-0.81.51.10.6
Pavlov. Cond. change in total contacts0.91.42.71.6-1.11.11.21.0-1.21.31.40.8
Pavlov. Cond. index score0.91.22.11.5-1.21.21.10.7-1.31.21.10.4
Pavlov. Cond. latency score0.91.22.01.4-1.21.21.10.9-1.01.11.20.7
Pavlov. Cond. lever contacts0.30.41.00.7-0.60.60.50.2-1.00.80.3-0.0
Pavlov. Cond. magazine entry number2.32.85.2-2.31.9-1.9-1.9-1.11.2-1.8-1.6-0.6
Pavlov. Cond. intertrial magazine entries0.50.82.0-1.10.3-0.3-0.7-1.40.2-0.5-1.2-1.4
Pavlov. Cond. lever-magazine prob. diff.1.11.42.71.6-1.31.31.30.7-1.21.21.20.4
Pavlov. Cond. response bias0.71.02.61.2-0.80.80.60.4-1.61.60.60.2
Time in closed arm before self-admin0.30.41.40.6-0.20.2-0.10.7-1.20.90.50.5
Time in closed arm after self-admin0.10.10.3-0.0-0.30.30.10.20.6-0.20.30.6
Time in open arm before self-admin0.10.10.20.00.3-0.30.3-0.20.5-0.3-0.1-0.1
Time in open arm after self-admin0.40.41.20.6-0.70.71.1-0.5-0.4-0.5-0.0-0.7
Bone: periosteal estimation0.20.30.70.40.8-0.8-0.20.6-0.60.80.20.2
Bone: periosteal perimeter0.20.41.70.70.1-0.10.10.2-1.21.30.2-0.2
Bone: post-yield work0.10.20.70.10.7-0.7-0.20.2-0.20.9-0.20.1
Progressive ratio test 1 active lever presses0.40.41.51.20.3-0.31.10.2-0.30.50.80.5
Progressive ratio test 1 breakpoint0.30.41.41.20.3-0.31.00.1-0.30.40.70.4
Progressive ratio test 1 inactive lever presses0.60.92.81.10.2-0.20.10.8-1.61.70.60.4
Progressive ratio test 2 active lever presses0.60.71.70.20.6-0.6-0.0-1.3-0.90.5-0.9-1.1
Progressive ratio test 2 breakpoint0.60.71.80.20.6-0.60.0-1.4-1.00.4-0.9-1.1
Progressive ratio test 2 inactive lever presses0.10.20.5-0.10.4-0.4-0.1-0.7-0.10.2-0.5-0.6
Incentive Sensitization - Responses0.71.13.3-0.30.4-0.4-0.3-1.8-0.90.0-1.4-1.7
Incentive Sensitization - Breakpoint0.71.03.0-0.20.2-0.2-0.2-1.7-1.00.1-1.3-1.6
Sum of active levers in priming session hrs 5-61.91.84.50.40.0-0.00.62.11.5-0.82.02.1
Progressive ratio1.21.85.12.3-0.90.91.80.0-1.61.80.8-0.1
Food seeking constrained by brief footshock1.01.23.1-0.4-0.70.70.01.41.8-0.91.41.6
Seeking ratio, punishment vs. effort1.82.66.2-2.00.4-0.4-1.51.62.5-2.00.81.8
Retroperitoneal fat weight0.52.14.01.9-0.70.71.11.9-0.81.52.01.8
Reaction time number correct1.42.87.4-2.12.4-2.4-2.70.10.1-0.2-1.40.1
Reaction time mean minus median0.71.84.41.4-1.11.10.9-0.5-2.12.00.2-1.3
Reaction time mean minus median AUC0.82.16.71.0-0.50.50.3-1.2-2.62.2-0.7-1.9
Reaction time num false alarms0.81.24.4-0.6-1.01.00.40.72.1-1.60.60.7
Reaction time num false alarms AUC0.81.34.4-0.6-1.31.30.60.52.1-1.50.50.4
Reaction time trials correct on left1.42.87.4-2.12.4-2.4-2.70.10.1-0.2-1.40.1
Reaction time trials on left1.32.56.7-2.02.2-2.2-2.60.10.1-0.2-1.30.1
Reaction time mean5.99.422.13.7-4.54.54.70.2-0.91.02.4-0.4
Reaction time mean AUC5.08.018.93.3-4.24.24.30.3-0.70.72.3-0.3
Median of all reaction times8.211.728.14.0-5.05.05.30.8-0.20.53.10.3
Reaction time omissions1.01.53.50.7-1.91.91.3-1.1-0.40.1-0.1-1.5
Reaction time false alarm rate1.31.83.80.4-2.02.01.70.31.7-1.31.00.2
Reaction time premature initiation rate2.94.19.22.1-1.11.11.72.90.60.23.03.0
Reaction time premature initiations1.22.17.50.70.2-0.2-0.02.60.70.11.92.7
Std. dev. reaction times2.34.27.62.6-2.82.82.70.1-1.81.71.4-0.7
Reaction time trials completed1.32.56.7-2.02.2-2.2-2.60.10.1-0.2-1.30.1
Reaction time trials AUC1.32.56.6-2.12.2-2.2-2.60.20.4-0.4-1.20.2
Run reversals in cocaine runway, females0.40.41.10.4-1.01.0-0.00.3-0.70.80.20.5
Run reversals in cocaine runway, males0.60.61.5-0.60.9-0.90.2-0.61.2-1.00.0-0.3
Latency to leave start box in cocaine runway1.01.24.30.71.0-1.0-0.1-0.3-1.72.1-0.6-0.8
Latency to leave start box in cocaine runway, F1.01.22.1-0.61.4-1.4-0.6-1.3-0.30.4-1.4-1.4
Latency to leave start box in cocaine runway, M2.72.56.82.1-0.90.91.11.6-1.92.61.20.8
Std. dev. time between licks in bursts0.60.82.90.9-1.01.01.70.00.5-0.80.80.2
Total sessions with >9 infusions0.30.41.10.40.5-0.5-0.0-0.6-0.91.0-0.5-0.5
Short access day 1 total inactive lever presses1.72.35.42.1-1.91.92.3-0.0-1.40.81.0-0.2
Short access day 10 total inactive lever presses0.20.51.6-1.0-0.30.3-0.40.31.2-1.3-0.00.2
Short access day 1 total infusions0.30.41.50.7-0.20.20.3-0.4-1.01.2-0.3-0.4
Short access day 10 total infusions0.50.62.01.40.2-0.20.9-0.2-0.91.40.40.1
Short access total infusions0.30.41.60.70.7-0.70.1-0.3-0.81.3-0.3-0.2
Short access day 1 locomotion0.91.23.61.4-0.90.90.60.3-1.61.90.40.4
Short access day 10 total locomotion0.61.23.21.8-1.01.01.50.3-1.10.90.90.3
Short access total locomotion0.20.31.00.70.0-0.00.2-0.2-0.81.0-0.00.0
One hour access (0.3 mA shock)0.91.02.31.2-0.30.31.0-1.5-1.50.8-0.4-1.2
Compulsive drug intake0.50.61.6-0.6-0.20.20.2-1.31.1-1.1-0.6-0.9
One hour access (shock baseline)0.50.83.01.00.1-0.10.6-1.0-1.71.0-0.4-1.0
Social response proportion1.31.45.6-0.4-0.50.50.90.22.4-2.20.60.7
Social responses0.91.14.1-1.20.8-0.8-0.50.32.0-1.6-0.30.4
Social time0.20.30.90.6-0.90.90.60.2-0.40.30.30.3
Soleus weight0.72.04.2-1.52.1-2.1-1.6-0.9-0.0-0.5-1.6-0.8
Bone: stiffness0.81.33.71.6-0.60.60.51.0-1.41.91.10.8
Tibialis anterior weight0.20.51.8-0.4-0.80.80.30.01.3-1.10.2-0.0
Time to tail flick, vehicle, before self-admin2.93.06.20.8-2.52.51.61.61.5-0.91.71.6
Time to tail flick, vehicle, after self-admin0.60.81.50.3-1.21.2-0.41.2-0.61.10.50.8
Time to tail flick, test, before self-admin1.01.03.70.10.3-0.3-0.71.90.10.31.21.8
Time to tail flick, test, after self-admin1.41.55.10.8-0.10.1-0.12.0-0.10.51.82.3
Delta time to tail flick, vehicle, before/after SA1.51.42.0-0.51.3-1.3-1.2-1.2-1.41.0-1.4-1.3
Delta time to tail flick, test, before/after SA0.10.10.40.10.0-0.0-0.0-0.3-0.60.4-0.2-0.3
Tibia length0.71.94.4-0.51.0-1.0-1.0-1.8-1.41.0-1.5-2.1
Ambulatory time before self-admin1.42.15.01.8-1.61.60.90.8-2.21.90.80.5
Ambulatory time after self-admin0.00.00.10.10.3-0.3-0.0-0.1-0.20.1-0.2-0.1
Bone: tissue strength0.30.30.9-0.90.2-0.2-0.90.30.6-0.7-0.00.5
Total heroin consumption0.50.62.4-0.40.3-0.30.10.81.5-1.10.60.7
Bone: trabecular number0.71.12.71.2-1.51.51.6-0.7-0.50.30.0-0.4
Bone: trabecular spacing1.41.93.9-0.41.7-1.7-1.7-0.1-2.01.6-1.1-0.6
Bone: trabecular thickness1.31.63.9-0.2-0.10.10.31.62.0-1.51.41.9
Bone: trabecular tissue density0.81.22.9-0.71.0-1.0-1.01.41.2-0.80.81.7
Water consumed over 24 hours0.60.71.8-0.70.8-0.8-0.60.71.3-1.10.41.0
Number of responses in last shaping day1.01.12.5-0.71.1-1.1-0.51.01.6-1.40.41.3