Hub : Genes

Tmem8b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr5_62735752_62735831 0.1 0.09 8.7e-03 0.01 0 0 0.01 1.6e-02 3.4e-01 2.1e-01 7.7e-02
2 Adipose gene expression Tmem8b 0.06 0.05 7.5e-07 0.07 0.06 0.05 0.07 1.4e-08 4.1e-07 1.9e-06 3.5e-08
3 PL intron excision ratio chr5_62735752_62735831 0.03 0.02 1.6e-04 0.03 0.03 0.04 0.03 3.2e-04 2.0e-04 9.8e-05 1.7e-04
4 PL gene expression Tmem8b 0.09 0.05 3.1e-12 0.12 0.12 0.12 0.12 6.0e-13 1.4e-12 1.3e-12 7.7e-13
5 PL intron excision ratio chr5_62735490_62735629 0.02 0.02 1.2e-03 0.02 0.02 0.02 0.02 2.3e-03 1.9e-03 1.5e-03 3.2e-03
6 NAcc gene expression Tmem8b 0.04 0.02 3.9e-07 0.05 0.04 0.04 0.05 4.1e-08 3.3e-06 2.0e-07 4.4e-08
7 Brain isoform ratio NM_001427449.1 0.03 0.02 4.2e-03 0.01 0.01 0.01 0.01 2.9e-02 2.3e-02 1.8e-02 2.3e-02
8 IC gene expression Tmem8b 0.23 0.1 4.8e-11 0.23 0.24 0.2 0.24 6.3e-10 1.1e-10 6.3e-09 2.1e-10
9 BLA gene expression Tmem8b 0.04 0.03 8.8e-03 0.02 0.01 0 0 4.8e-02 1.0e-01 1.7e-01 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.93.23.9-1.5-1.8-1.8-1.71.8-1.7-1.9-2.0-1.9
Area under the delay curve0.91.11.90.71.01.41.0-1.41.00.71.00.9
BMI with tail1.96.78.1-2.4-2.5-2.5-2.32.5-2.6-2.8-2.7-2.8
BMI without tail2.37.07.8-2.7-2.6-2.7-2.62.7-2.8-2.6-2.5-2.5
Body weight2.812.016.1-4.0-3.4-3.5-3.33.5-3.4-3.8-3.0-3.3
Weight adjusted by age0.10.20.6-0.6-0.2-0.4-0.10.4-0.3-0.8-0.1-0.1
Bone surface0.91.72.2-1.3-1.3-1.3-1.21.3-1.2-1.5-1.2-1.4
Bone volume0.91.62.1-1.0-1.3-1.3-1.21.3-1.2-1.4-1.4-1.4
Breakpoint value in progressive ratio session2.32.74.90.02.01.62.0-1.61.70.92.21.7
Number of licking bursts3.86.27.0-2.3-2.5-2.6-2.62.6-2.5-2.5-2.5-2.3
Context. condit. distance diff. score0.00.00.10.30.20.20.2-0.20.20.2-0.0-0.1
Locomotion velocity, session 10.40.51.5-1.20.30.50.4-0.50.4-0.41.10.4
Locomotion distance, session 10.10.10.6-0.80.10.1-0.0-0.1-0.1-0.30.50.4
Locomotion velocity, session 23.13.64.1-1.7-2.0-2.0-2.02.0-1.9-1.7-2.0-1.9
Locomotion distance, session 21.01.43.4-1.8-1.2-1.3-1.31.2-1.3-1.0-0.40.0
Locomotion velocity, session 30.20.20.5-0.40.40.40.3-0.40.3-0.00.70.4
Locomotion distance, session 31.82.04.2-1.7-1.1-1.2-1.21.2-1.2-2.0-1.1-1.6
Stereotopy head waving bouts, day 30.70.82.0-0.00.70.80.8-0.80.80.71.31.4
Stereotopy head waving duration, day 30.70.81.70.30.70.80.8-0.80.80.91.11.3
Locomotion velocity, session 70.10.10.10.30.40.40.3-0.40.30.30.30.2
Locomotion distance, session 70.10.10.4-0.6-0.3-0.3-0.20.3-0.3-0.5-0.2-0.5
Stereotopy head waving bouts, day 71.01.12.2-1.4-1.0-0.9-0.90.9-0.9-1.5-0.8-0.9
Stereotopy head waving duration, day 70.40.40.9-1.0-0.8-0.7-0.60.6-0.6-0.7-0.4-0.3
Locomotion velocity, session 80.40.51.7-0.30.40.30.3-0.40.40.71.11.3
Locomotion distance, session 80.10.10.5-0.7-0.0-0.1-0.10.0-0.1-0.00.40.5
Degree of sensitization distance1.31.32.81.00.91.01.0-1.01.01.71.21.4
Degree of sensitization stereotypy1.61.73.0-1.2-1.2-1.1-1.11.2-1.1-1.7-1.3-1.5
Conditioned locomotion0.20.30.4-0.10.60.70.6-0.60.6-0.30.4-0.1
Cocaine response after cond. corrected2.73.24.01.31.91.92.0-1.91.91.42.01.6
Cocaine response after cond. not corrected2.73.24.91.11.71.81.9-1.81.81.62.22.0
Cocaine response before conditioning0.60.71.1-0.9-1.0-1.0-1.01.0-0.9-0.4-0.5-0.2
Saline control response0.20.31.0-1.0-0.5-0.6-0.60.5-0.4-0.50.0-0.3
Bone: connectivity density1.21.92.7-1.1-1.4-1.3-1.31.3-1.3-1.6-1.6-1.5
Bone: cortical apparent density0.20.20.50.2-0.6-0.5-0.50.5-0.4-0.0-0.7-0.4
Bone: cortical area3.14.75.8-1.6-2.1-2.4-2.22.4-2.3-1.9-2.4-2.1
Bone: cortical porosity0.10.10.20.20.40.40.4-0.40.20.30.30.4
Bone: cortical porosity0.00.00.1-0.20.00.0-0.0-0.0-0.1-0.2-0.1-0.1
Bone: cortical thickness1.42.44.2-0.5-1.4-1.6-1.41.6-1.5-1.4-2.0-1.8
Bone: cortical thickness0.10.10.40.70.40.10.3-0.10.40.60.00.1
Bone: cortical tissue density0.10.10.30.2-0.5-0.4-0.30.4-0.20.1-0.6-0.3
Condit. Reinf. active minus inactive responses0.60.71.0-0.9-1.0-0.9-1.00.9-0.8-0.6-0.7-0.6
Condit. Reinf. active-inactive response ratio0.50.50.80.90.60.70.7-0.70.90.80.60.6
Condit. Reinf. active responses3.44.25.4-2.1-2.3-2.2-2.32.1-2.2-1.7-1.8-1.6
Condit. Reinf. inactive responses4.25.17.0-2.2-2.5-2.4-2.52.4-2.6-1.8-2.1-1.6
Incentive salience index mean4.55.57.2-2.7-2.5-2.4-2.52.3-2.4-2.3-2.0-1.9
Condit. Reinf. lever presses9.212.919.5-4.4-3.8-3.5-3.73.5-3.7-3.7-2.9-2.9
Condit. Reinf. active minus inactive responses0.91.11.8-0.7-1.0-1.1-1.11.1-1.0-1.0-1.1-1.3
Condit. Reinf. active-inactive response ratio0.30.41.0-0.1-0.5-0.6-0.50.6-0.5-0.6-0.8-1.0
Condit. Reinf. active responses2.33.23.6-1.7-1.8-1.8-1.91.8-1.9-1.7-1.7-1.8
Condit. Reinf. inactive responses2.93.74.6-1.9-2.1-2.0-2.11.9-2.1-1.7-1.8-1.6
Condit. Reinf. lever presses3.54.96.1-1.7-2.4-2.3-2.42.3-2.5-1.8-2.3-2.1
Condit. Reinf. lever reinforcers received2.73.74.3-1.9-2.0-2.0-2.12.0-2.1-1.8-1.8-1.8
Conditioned reinforcement - actives0.10.10.5-0.10.20.10.3-0.0-0.1-0.7-0.2-0.6
Conditioned reinforcement - inactives0.40.61.00.11.01.01.0-0.90.90.30.70.2
Conditioned locomotion0.20.31.1-0.00.30.40.3-0.40.2-0.8-0.1-1.0
Patch foraging indifference point 0 sec0.30.51.8-1.30.40.60.5-0.50.2-1.30.3-0.5
Patch foraging indifference point AUC7.611.013.1-3.6-3.4-3.4-3.43.4-3.3-3.5-2.8-3.0
Delay disc. indifference point, 0s delay1.51.62.20.71.31.31.3-1.31.21.41.51.4
Delay disc. indifference point, 16s delay2.12.33.50.81.61.91.6-1.91.80.71.61.1
Delay disc. indifference point, 2s delay0.10.10.2-0.2-0.4-0.1-0.40.1-0.5-0.2-0.5-0.4
Delay disc. indifference point, 24s delay0.10.10.20.10.30.30.3-0.40.30.50.40.4
Delay disc. indifference point, 4s delay0.20.30.90.90.30.70.3-0.60.20.30.40.3
Delay disc. indifference point, 8s delay0.00.00.1-0.2-0.10.1-0.1-0.1-0.1-0.0-0.00.1
Indifference point function ln k2.44.35.01.92.22.22.2-2.22.12.01.81.9
Indifference point function log k2.44.35.01.92.22.22.2-2.22.12.01.81.9
Patch foraging total patch changes 0 sec0.40.73.0-1.7-0.00.10.0-0.0-0.2-1.7-0.2-0.9
Patch foraging total patch changes 12 sec2.83.65.7-1.9-1.6-1.7-1.61.8-1.8-2.4-1.9-2.2
Patch foraging total patch changes 18 sec0.60.81.3-1.2-0.9-0.9-0.90.9-1.0-1.0-0.7-0.8
Patch foraging total patch changes 24 sec1.83.15.8-2.0-1.6-1.6-1.61.7-1.6-2.4-1.5-1.9
Patch foraging total patch changes 6 sec2.13.26.8-2.5-1.4-1.3-1.31.3-1.7-2.6-1.4-2.0
Patch foraging time to switch 0 sec1.83.75.82.41.91.81.8-1.81.62.41.52.0
Patch foraging water rate 0 sec1.22.66.7-1.8-1.2-1.1-1.11.2-1.1-2.6-1.4-2.3
Patch foraging water rate 12 sec0.00.10.10.20.20.30.3-0.30.3-0.10.2-0.2
Patch foraging water rate 18 sec0.71.03.1-0.4-0.6-0.8-0.70.9-0.6-1.4-1.3-1.8
Patch foraging water rate 24 sec0.20.31.10.2-0.3-0.3-0.20.4-0.2-0.6-0.8-1.1
Patch foraging water rate 6 sec0.40.60.9-0.6-0.7-0.9-0.80.9-0.4-0.8-0.5-0.7
Seeking ratio, delayed vs. immediate footshock3.74.66.3-1.5-2.0-2.1-1.92.1-2.3-2.5-2.3-2.4
Distance traveled before self-admin1.62.13.4-1.4-1.5-1.6-1.61.6-1.4-1.8-1.0-1.0
Distance traveled after self-admin1.01.32.0-0.7-1.4-1.2-1.41.2-1.3-0.8-1.1-0.9
Extensor digitorum longus weight4.718.524.5-4.9-4.2-4.2-4.34.2-4.3-4.7-3.9-3.9
Bone: elastic displacement3.84.48.12.82.32.22.2-2.12.22.11.41.2
Bone: elastic work0.81.04.52.10.90.80.9-0.70.81.0-0.2-0.3
Bone: endosteal estimation0.81.83.2-1.8-1.4-1.6-1.41.5-1.3-1.1-0.7-0.8
Bone: endosteal perimeter0.71.53.2-1.8-1.2-1.3-1.21.3-1.2-1.3-0.7-1.0
Epididymis fat weight0.41.52.1-1.2-1.4-1.4-1.41.3-1.4-0.6-1.1-0.8
Delta time in closed arm before/after self-admin1.01.01.50.1-1.0-1.2-1.01.2-1.2-0.4-1.1-0.9
Delta time in open arm before/after self-admin0.60.61.1-0.00.91.10.8-1.10.70.30.90.6
Diff in mean of infusions in LGA sessions0.10.10.50.1-0.1-0.2-0.00.2-0.10.70.00.3
Delay discount exponential model param0.80.91.7-0.6-0.9-1.3-0.91.3-0.9-0.6-0.9-0.7
Extinction: sum of active levers before priming4.34.86.51.32.32.52.3-2.61.82.22.22.2
Active lever presses in extinction session 60.30.30.50.50.70.60.7-0.60.40.20.40.2
Bone: final force1.52.33.4-1.5-1.6-1.9-1.81.8-1.7-1.1-1.3-0.8
Bone: final moment1.32.03.2-1.2-1.6-1.8-1.71.7-1.6-0.9-1.2-0.7
Food consumed during 24 hour testing period0.40.50.9-1.0-0.8-0.8-0.80.8-0.7-0.6-0.4-0.2
Glucose2.74.25.3-2.3-2.0-2.0-2.02.0-2.2-2.1-1.8-2.1
Heart weight0.60.91.7-1.0-1.1-0.9-1.00.9-1.3-0.7-0.8-0.4
Delay discount hyperbolic model param0.50.61.2-0.5-0.8-1.1-0.81.1-0.7-0.4-0.8-0.5
Intermittent access intake day 1-15 change0.71.31.8-0.6-1.2-1.3-1.21.3-1.1-0.9-1.3-1.3
Intermittent access intake escalation0.61.21.7-0.4-1.2-1.3-1.21.3-1.0-0.7-1.2-1.2
Intermittent access intake escalation 22.02.33.2-0.4-1.5-1.7-1.51.7-1.5-1.1-1.8-1.7
Intermitt. access day 1 inactive lever presses0.31.33.9-2.0-1.0-1.0-1.11.0-1.0-1.1-0.8-1.0
Intermitt. access day 15 inactive lever presses0.00.00.00.10.1-0.10.10.1-0.0-0.10.10.1
Intermitt. access escalation Index0.30.41.5-1.2-0.6-0.6-0.60.5-0.5-0.2-0.20.2
Intermittent access day 1 total infusions1.52.54.50.92.01.92.1-1.81.80.41.50.7
Intermittent access day 15 total infusions0.10.21.0-0.0-0.0-0.20.10.3-0.1-0.7-0.5-1.0
Intermittent access terminal intake (last 3 days)0.20.31.2-0.40.0-0.30.10.4-0.1-0.9-0.5-1.1
Intermittent access total infusions0.20.31.0-0.40.30.10.40.00.1-0.9-0.3-1.0
Intermittent access day 1 locomotion1.52.03.60.71.81.91.8-1.81.50.41.10.2
Intermittent access day 15 total locomotion0.81.42.51.11.61.31.6-1.21.50.20.90.0
Intermittent access total locomotion1.11.32.21.31.41.31.5-1.31.30.50.6-0.2
Intermittent access standard deviation0.20.31.0-0.3-0.3-0.4-0.30.4-0.6-1.0-0.6-0.9
Left kidney weight0.21.03.0-1.7-0.9-1.1-1.01.0-1.1-0.9-0.3-0.3
Right kidney weight0.31.42.7-1.6-1.3-1.2-1.31.2-1.5-0.7-0.8-0.6
Cocaine induced anxiety0.20.31.00.50.30.40.3-0.50.71.00.50.4
Post-drug Anxiety0.20.20.8-0.9-0.6-0.5-0.60.4-0.30.20.10.3
Baseline Anxiety0.70.81.4-1.1-1.0-0.9-1.00.8-1.2-0.6-0.7-0.2
Tail length1.56.07.9-2.7-2.6-2.8-2.72.7-2.6-2.0-1.8-1.6
Length with tail0.93.98.4-2.9-1.9-2.0-2.02.0-1.9-2.1-1.2-1.4
Length without tail0.00.10.3-0.40.40.30.3-0.30.4-0.30.60.2
Times rat made contact with spout0.60.61.1-0.5-0.7-0.8-0.70.8-0.7-0.8-1.0-0.9
Lifetime Intake0.20.30.7-0.20.60.30.7-0.30.4-0.80.2-0.7
Liver weight, left0.10.21.0-0.20.30.20.3-0.30.20.60.61.0
Liver weight, right0.71.22.11.51.21.11.1-1.11.01.10.80.7
Locomotor activity0.00.00.3-0.50.00.00.0-0.10.00.10.10.2
Locomotor testing distance0.40.71.3-0.10.90.80.9-0.90.80.71.11.1
Locomotor testing rearing0.20.51.7-1.3-0.6-0.7-0.60.7-0.6-0.3-0.1-0.1
Locomotion in novel chamber0.10.20.70.80.20.50.2-0.40.10.3-0.2-0.2
Locomotion in novel chamber post-restriction1.83.04.9-0.4-1.9-2.2-1.92.2-1.7-1.1-1.9-1.5
Fecal boli incidents, locomotor time 10.30.40.80.70.60.90.6-0.90.40.80.40.4
Change in fecal boli incidents, locomotor task0.40.40.8-0.9-0.5-0.7-0.50.7-0.3-0.6-0.3-0.6
Time >=10cm from walls, locomotor time 10.10.20.3-0.40.40.40.3-0.40.5-0.10.50.4
Bouts of movement, locomotor time 11.71.92.21.31.21.51.3-1.51.41.51.21.5
Total resting periods, locomotor time 11.82.02.91.71.31.41.3-1.41.31.61.11.4
Rest time, locomotor task time 10.40.52.41.50.10.10.1-0.10.11.2-0.00.5
Distance moved, locomotor task time 10.60.82.7-1.6-0.6-0.7-0.60.7-0.4-1.5-0.3-0.8
Vertical activity count, locomotor time 10.10.31.5-1.2-0.0-0.2-0.10.10.3-0.80.60.5
Time >=10cm from walls, locomotor time 20.00.00.1-0.0-0.1-0.3-0.10.2-0.2-0.40.10.1
Bouts of movement, locomotor time 20.30.40.8-0.9-0.7-0.2-0.60.2-0.9-0.7-0.6-0.5
Total resting periods, locomotor time 20.10.20.4-0.7-0.40.1-0.4-0.0-0.6-0.4-0.4-0.3
Rest time, locomotor task time 20.40.51.21.10.70.60.6-0.60.80.90.60.5
Distance moved, locomotor task time 20.60.71.1-0.2-1.0-1.0-1.01.0-0.8-0.6-0.7-0.4
Vertical activity count, locomotor time 20.20.30.8-0.3-0.7-0.9-0.60.8-0.5-0.5-0.10.5
Light reinforcement 10.20.62.8-1.70.30.20.1-0.30.0-0.11.21.0
Light reinforcement 20.61.02.5-1.30.70.50.5-0.60.70.11.61.6
Bone: marrow area1.02.13.4-1.8-1.6-1.7-1.61.7-1.4-1.2-0.9-0.9
Bone: maximum diameter2.85.26.2-2.1-2.3-2.5-2.42.5-2.4-2.0-2.2-1.9
Bone: maximum force3.15.67.0-2.3-2.5-2.6-2.62.6-2.6-2.0-2.1-1.7
Bone: maximum moment2.74.76.2-2.0-2.3-2.5-2.52.4-2.4-1.8-2.0-1.5
Mean time between licks in bursts0.51.13.40.70.70.60.7-0.70.71.71.21.8
Mean num. licks in bursts1.72.62.91.61.61.71.6-1.71.71.71.51.5
Cd content in liver0.50.61.1-1.0-0.8-1.1-0.71.0-0.6-0.5-0.4-0.2
Co content in liver1.11.31.90.71.31.00.9-1.11.21.21.41.4
Cu content in liver1.92.33.91.71.31.21.3-1.21.52.01.41.7
Fe content in liver2.02.53.71.11.71.41.4-1.51.61.81.91.7
K content in liver0.50.50.80.40.70.70.6-0.70.80.50.90.9
Mg content in liver0.60.60.80.80.90.90.7-0.80.80.50.60.6
Mn content in liver1.61.82.2-0.8-1.5-1.5-1.51.5-1.5-1.1-1.5-1.1
Na content in liver2.42.55.71.61.41.11.1-1.21.42.41.71.9
Rb content in liver6.77.89.93.13.02.62.5-2.62.92.82.62.8
Se content in liver2.93.55.2-2.0-2.3-2.0-1.71.9-2.2-1.3-1.7-1.5
Sr content in liver0.60.61.6-1.3-1.0-0.6-0.40.6-1.0-0.5-0.5-0.3
Zn content in liver0.10.10.4-0.1-0.3-0.4-0.60.4-0.30.2-0.20.0
Bone: minimum diameter0.00.10.10.2-0.1-0.3-0.10.3-0.10.1-0.3-0.4
Time in familiar zone, hab. session 10.40.41.40.8-0.3-0.3-0.20.4-0.2-0.1-1.2-1.1
Time in novel zone, hab. session 14.44.48.60.91.91.91.8-2.01.82.12.82.9
Total zone transitions, hab. session 10.00.00.2-0.1-0.2-0.1-0.20.1-0.30.10.00.4
Total locomotion distance, hab. session 10.81.11.7-0.6-1.3-1.2-1.21.2-1.3-0.5-1.2-0.4
Locomotion velocity, hab. session 12.23.14.2-1.5-2.1-1.9-2.01.9-2.0-1.3-1.8-1.0
Time in familiar zone, hab. session 20.20.21.11.10.20.30.3-0.30.40.6-0.10.1
Time in novel zone, hab. session 22.42.53.60.91.71.61.7-1.71.61.21.91.6
Total zone transitions, hab. session 20.20.30.9-1.0-0.5-0.5-0.60.5-0.6-0.6-0.10.0
Total locomotion distance, hab. session 20.81.11.4-1.2-1.2-1.1-1.11.1-1.1-0.9-0.9-0.6
Locomotion velocity, hab. session 21.21.61.9-1.4-1.4-1.4-1.31.3-1.3-1.1-1.1-0.8
Novel to familiar place preference ratio4.75.16.01.92.52.42.3-2.42.32.02.42.2
Novelty place preference5.96.37.52.22.72.62.6-2.62.62.32.62.3
Time in novel zone, NPP test7.47.99.12.53.02.92.8-2.92.92.62.92.7
Total zone transitions, NPP test0.30.41.4-1.2-0.6-0.5-0.60.5-0.6-0.60.00.2
Total locomotion distance, NPP test1.41.94.0-2.0-1.4-1.3-1.41.3-1.4-1.6-0.9-1.0
Locomotion velocity, NPP test2.23.15.0-2.2-1.8-1.7-1.71.7-1.7-2.0-1.4-1.4
Intraocular pressure2.23.14.9-2.1-1.6-1.6-1.51.7-1.6-2.2-1.5-1.9
Delta distance traveled before/after self-admin0.10.10.3-0.2-0.10.1-0.1-0.10.10.50.10.4
Delta ambulatory time before/after self-admin0.40.41.30.30.40.50.5-0.60.61.10.60.9
Parametrial fat weight0.30.81.70.60.80.70.8-0.70.70.91.21.3
Pavlov. Cond. lever latency6.38.011.13.33.02.82.8-2.82.92.92.42.4
Pavlov. Cond. magazine entry latency0.50.71.0-1.0-1.0-0.9-0.90.9-0.9-0.5-0.6-0.5
Pavlov. Cond. change in total contacts2.52.63.7-1.9-1.7-1.6-1.61.6-1.5-1.7-1.3-1.5
Pavlov. Cond. index score3.24.15.2-2.3-2.3-2.1-2.12.1-2.2-1.8-1.7-1.6
Pavlov. Cond. latency score3.03.84.8-2.2-2.2-2.0-2.02.0-2.1-1.8-1.6-1.6
Pavlov. Cond. lever contacts6.27.49.5-3.1-2.9-2.7-2.72.7-2.8-2.8-2.4-2.4
Pavlov. Cond. magazine entry number0.81.11.31.01.21.11.1-1.11.10.81.00.9
Pavlov. Cond. intertrial magazine entries0.30.30.5-0.6-0.7-0.6-0.70.6-0.7-0.5-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.3.54.35.5-2.2-2.3-2.2-2.22.1-2.2-1.8-1.8-1.7
Pavlov. Cond. response bias3.84.76.3-2.5-2.4-2.2-2.32.2-2.2-2.0-1.8-1.7
Pavlov. Cond. lever latency3.24.45.71.72.32.22.3-2.22.41.62.11.9
Pavlov. Cond. magazine entry latency0.30.31.10.80.30.30.3-0.40.21.00.50.9
Pavlov. Cond. change in total contacts1.21.93.0-0.5-1.7-1.6-1.61.6-1.7-0.6-1.6-1.0
Pavlov. Cond. index score0.50.71.1-0.1-1.0-1.0-1.00.9-1.1-0.1-0.9-0.4
Pavlov. Cond. latency score0.71.01.5-0.2-1.2-1.1-1.11.1-1.2-0.3-1.1-0.7
Pavlov. Cond. lever contacts2.43.34.6-1.4-2.1-2.0-2.02.0-2.1-1.3-1.8-1.5
Pavlov. Cond. magazine entry number0.30.40.7-0.20.80.70.8-0.70.8-0.10.80.3
Pavlov. Cond. intertrial magazine entries0.30.51.1-0.7-0.4-0.6-0.50.6-0.5-1.0-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.71.2-0.1-1.1-1.0-1.01.0-1.1-0.0-0.9-0.5
Pavlov. Cond. response bias1.21.62.5-0.7-1.5-1.4-1.51.4-1.6-0.6-1.3-0.8
Time in closed arm before self-admin0.30.41.00.80.61.00.6-0.90.80.20.2-0.2
Time in closed arm after self-admin0.20.21.21.1-0.1-0.3-0.00.30.00.4-0.4-0.1
Time in open arm before self-admin0.70.82.2-1.5-0.7-1.1-0.71.1-0.8-0.7-0.2-0.1
Time in open arm after self-admin0.60.62.5-1.6-0.4-0.3-0.50.3-0.6-1.2-0.3-0.6
Bone: periosteal estimation1.73.65.0-1.9-2.0-2.2-2.02.2-2.0-1.6-1.7-1.5
Bone: periosteal perimeter0.40.71.2-1.1-0.7-0.9-0.80.9-0.8-0.8-0.6-0.7
Bone: post-yield work1.62.34.8-2.2-1.6-1.6-1.61.5-1.6-1.5-0.9-0.7
Progressive ratio test 1 active lever presses0.91.12.70.41.51.11.6-1.11.4-0.10.9-0.1
Progressive ratio test 1 breakpoint0.70.92.20.31.41.01.5-0.91.2-0.20.8-0.2
Progressive ratio test 1 inactive lever presses0.20.31.8-1.30.0-0.20.10.20.0-1.00.2-0.5
Progressive ratio test 2 active lever presses1.31.53.10.41.71.41.8-1.31.40.01.30.5
Progressive ratio test 2 breakpoint1.41.63.30.51.71.41.8-1.41.50.11.30.5
Progressive ratio test 2 inactive lever presses0.20.30.9-0.60.1-0.30.10.3-0.1-1.0-0.3-0.9
Incentive Sensitization - Responses0.50.71.30.41.10.91.0-0.91.00.31.00.6
Incentive Sensitization - Breakpoint0.60.81.40.51.21.01.0-1.01.00.31.00.7
Sum of active levers in priming session hrs 5-64.34.05.60.92.32.42.3-2.31.91.52.11.9
Progressive ratio0.00.00.1-0.30.20.30.2-0.3-0.10.00.10.0
Food seeking constrained by brief footshock4.96.012.0-3.4-2.2-1.8-2.21.9-2.3-3.5-2.0-2.3
Seeking ratio, punishment vs. effort1.42.03.1-1.6-1.5-1.3-1.41.4-1.2-1.8-1.2-1.3
Retroperitoneal fat weight0.31.43.11.61.10.91.0-0.90.91.80.81.1
Reaction time number correct0.00.10.4-0.50.10.0-0.1-0.00.1-0.7-0.0-0.3
Reaction time mean minus median0.61.62.8-0.5-1.3-1.3-1.51.3-1.7-0.6-1.7-0.9
Reaction time mean minus median AUC0.92.33.7-1.0-1.5-1.6-1.81.6-1.9-1.0-1.8-1.2
Reaction time num false alarms0.10.10.4-0.1-0.5-0.4-0.60.4-0.4-0.0-0.4-0.2
Reaction time num false alarms AUC0.30.50.9-0.7-0.7-0.7-0.90.7-0.8-0.6-0.7-0.6
Reaction time trials correct on left0.00.10.4-0.50.10.0-0.1-0.00.1-0.7-0.0-0.3
Reaction time trials on left0.00.10.3-0.40.20.1-0.0-0.10.2-0.60.1-0.2
Reaction time mean0.50.82.51.60.60.40.4-0.50.41.50.31.0
Reaction time mean AUC0.50.82.81.70.70.50.5-0.50.41.50.31.0
Median of all reaction times1.92.85.32.31.51.31.4-1.31.42.21.31.9
Reaction time omissions1.62.33.21.41.41.51.5-1.51.31.81.51.7
Reaction time false alarm rate0.00.10.10.2-0.3-0.2-0.30.2-0.30.3-0.2-0.0
Reaction time premature initiation rate1.41.94.42.11.51.51.5-1.41.51.30.60.4
Reaction time premature initiations0.81.42.71.71.41.41.3-1.31.30.70.60.2
Std. dev. reaction times0.20.30.70.3-0.5-0.6-0.70.5-0.80.5-0.70.1
Reaction time trials completed0.00.10.3-0.40.20.1-0.0-0.10.2-0.60.1-0.2
Reaction time trials AUC0.00.10.3-0.40.20.1-0.0-0.10.1-0.60.0-0.2
Run reversals in cocaine runway, females0.20.20.7-0.8-0.6-0.5-0.50.5-0.00.1-0.4-0.1
Run reversals in cocaine runway, males0.00.00.20.40.30.20.3-0.2-0.10.10.0-0.0
Latency to leave start box in cocaine runway0.60.71.0-0.5-0.9-0.8-0.80.8-0.7-0.9-1.0-0.9
Latency to leave start box in cocaine runway, F0.20.20.30.60.50.50.6-0.50.50.00.40.1
Latency to leave start box in cocaine runway, M1.81.62.2-1.4-1.5-1.3-1.51.3-1.1-1.2-1.2-1.0
Std. dev. time between licks in bursts0.30.40.70.60.60.60.6-0.60.60.80.60.7
Total sessions with >9 infusions0.40.40.8-0.20.80.80.9-0.70.8-0.30.7-0.2
Short access day 1 total inactive lever presses0.20.31.2-1.10.0-0.10.00.10.3-0.9-0.0-0.9
Short access day 10 total inactive lever presses0.30.81.0-1.0-1.0-0.9-1.00.9-1.0-0.7-1.0-0.8
Short access day 1 total infusions0.30.40.8-0.40.90.60.9-0.50.7-0.30.8-0.2
Short access day 10 total infusions0.50.61.2-0.21.00.81.1-0.81.0-0.20.90.1
Short access total infusions0.81.12.20.21.41.11.5-1.01.3-0.01.20.3
Short access day 1 locomotion2.02.43.91.01.92.02.0-1.91.60.91.50.5
Short access day 10 total locomotion0.50.91.61.30.91.30.9-1.20.60.90.4-0.1
Short access total locomotion0.80.91.90.21.11.41.1-1.31.00.50.90.0
One hour access (0.3 mA shock)0.10.10.5-0.40.1-0.30.10.3-0.0-0.7-0.0-0.4
Compulsive drug intake0.50.61.10.2-0.8-0.9-0.90.9-1.1-0.2-0.9-0.2
One hour access (shock baseline)0.20.30.8-0.30.80.40.9-0.40.5-0.70.6-0.3
Social response proportion2.12.36.41.71.11.01.1-1.11.42.51.41.8
Social responses0.60.81.2-1.1-1.1-1.0-1.11.0-1.0-0.3-0.6-0.5
Social time0.60.83.2-0.10.20.20.2-0.30.31.51.11.8
Soleus weight0.51.43.8-0.50.90.80.9-0.90.91.01.91.9
Bone: stiffness3.86.18.5-2.6-2.8-2.9-2.92.8-2.7-1.8-1.9-1.3
Tibialis anterior weight6.321.530.8-5.5-4.6-4.8-4.74.8-4.6-4.9-3.8-3.8
Time to tail flick, vehicle, before self-admin0.30.32.21.50.50.30.5-0.30.20.2-0.1-0.2
Time to tail flick, vehicle, after self-admin0.30.31.21.1-0.1-0.5-0.20.5-0.3-0.5-0.5-0.8
Time to tail flick, test, before self-admin0.50.50.7-0.9-0.8-0.6-0.80.6-0.7-0.6-0.7-0.7
Time to tail flick, test, after self-admin4.14.36.4-1.4-2.0-2.0-2.02.1-2.1-1.8-2.4-2.5
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.4-0.4-0.6-0.40.5-0.30.0-0.1-0.0
Delta time to tail flick, test, before/after SA0.20.20.70.4-0.3-0.4-0.30.4-0.4-0.3-0.7-0.8
Tibia length0.41.04.40.10.80.30.5-0.40.61.01.52.1
Ambulatory time before self-admin1.11.63.1-1.3-1.2-1.4-1.31.4-1.1-1.8-0.8-1.0
Ambulatory time after self-admin0.30.30.4-0.6-0.6-0.7-0.70.6-0.5-0.5-0.3-0.3
Bone: tissue strength0.20.20.7-0.2-0.4-0.4-0.50.3-0.50.50.10.8
Total heroin consumption2.52.93.90.81.91.92.0-1.91.91.21.91.5
Bone: trabecular number1.62.63.1-1.4-1.8-1.6-1.61.6-1.6-1.6-1.7-1.4
Bone: trabecular spacing0.00.00.10.1-0.0-0.2-0.20.2-0.10.2-0.3-0.2
Bone: trabecular thickness0.00.00.10.3-0.10.20.2-0.2-0.00.0-0.1-0.0
Bone: trabecular tissue density2.23.24.9-2.2-2.1-2.1-2.12.0-2.0-1.1-1.1-0.7
Water consumed over 24 hours0.91.21.6-0.8-1.0-1.1-1.01.1-0.9-1.2-1.2-1.3
Number of responses in last shaping day1.71.93.40.21.41.51.5-1.51.50.61.91.4