Hub : Genes

Tmem235

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_039087509.1 0.1 0.06 1.2e-12 0.1 0.1 0.1 0.11 8.2e-12 1.1e-11 1.5e-11 3.2e-12
2 LHb gene expression Tmem235 0.3 0.15 3.8e-07 0.18 0.22 0.2 0.2 4.0e-05 5.0e-06 2.1e-05 1.9e-05
3 pVTA gene expression Tmem235 0.09 0.06 5.7e-04 0.06 0.06 0.04 0.06 1.5e-03 9.5e-04 6.5e-03 1.1e-03
4 Brain isoform ratio XM_039087507.1 0.03 0.02 7.8e-04 0.03 0.03 0.03 0.03 1.8e-03 5.5e-04 2.1e-03 1.9e-03
5 NAcc isoform ratio XM_039087507.1 0.08 0.05 3.6e-10 0.08 0.07 0.09 0.09 6.1e-10 5.0e-09 4.2e-10 3.7e-10
6 Adipose gene expression Tmem235 0.05 0.04 1.3e-05 0.04 0.04 0.03 0.04 4.3e-05 3.1e-05 1.4e-04 6.4e-05
7 Adipose alternative TSS XM_039087507.1 0.02 0.01 7.7e-03 0 0.01 0 0.01 7.5e-02 1.9e-02 1.4e-01 7.0e-02
8 NAcc gene expression Tmem235 0.5 0.14 0.0e+00 0.39 0.39 0.39 0.39 8.1e-48 3.5e-48 2.4e-48 2.1e-48
9 BLA gene expression Tmem235 0.38 0.14 0.0e+00 0.31 0.29 0.29 0.3 3.5e-17 5.2e-16 7.9e-16 1.2e-16
10 BLA isoform ratio XM_039087509.1 0.11 0.07 9.3e-06 0.1 0.08 0.09 0.09 6.9e-06 3.8e-05 2.7e-05 2.2e-05
11 Brain gene expression Tmem235 0.53 0.15 0.0e+00 0.33 0.31 0.32 0.33 2.8e-31 2.1e-29 3.4e-30 3.4e-31
12 PL isoform ratio XM_039087509.1 0.18 0.09 0.0e+00 0.17 0.17 0.16 0.17 9.5e-19 2.6e-18 9.3e-18 7.6e-19
13 OFC isoform ratio XM_039087509.1 0.26 0.2 7.7e-04 0.12 0.09 0.1 0.1 1.2e-03 3.3e-03 2.3e-03 2.8e-03
14 IL gene expression Tmem235 0.74 0.11 1.4e-10 0.28 0.25 0.28 0.28 1.5e-07 9.4e-07 2.4e-07 1.7e-07
15 PL gene expression Tmem235 0.38 0.11 0.0e+00 0.4 0.42 0.42 0.42 1.9e-47 1.7e-49 3.2e-49 2.0e-49
16 IL isoform ratio XM_039087507.1 0.64 0.26 3.1e-03 0.09 0.05 0.06 0.07 3.9e-03 2.6e-02 1.4e-02 8.3e-03
17 IL isoform ratio XM_039087509.1 0.33 0.24 2.6e-03 0.11 0.06 0.08 0.09 1.3e-03 1.5e-02 6.8e-03 3.7e-03
18 OFC gene expression Tmem235 0.58 0.18 2.7e-10 0.28 0.25 0.26 0.26 2.9e-07 1.1e-06 9.1e-07 6.8e-07
19 PL isoform ratio XM_039087507.1 0.16 0.08 5.6e-17 0.16 0.15 0.15 0.16 5.3e-17 5.0e-16 4.5e-16 8.5e-17
20 Brain isoform ratio XM_039087509.1 0.08 0.05 1.4e-07 0.09 0.08 0.09 0.09 7.8e-09 6.5e-08 8.4e-09 9.1e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.50.82.2-0.81.01.11.30.5-0.91.50.5-0.50.6-0.6-0.70.5-0.50.8-0.50.5-1.1-1.11.5
Area under the delay curve0.60.71.50.9-1.1-1.2-0.7-0.61.1-1.2-0.60.6-0.70.70.8-0.50.5-0.80.5-0.51.01.0-0.8
BMI with tail0.10.31.10.20.10.3-1.1-0.4-0.20.0-0.40.5-0.60.60.6-0.30.3-0.70.2-0.20.80.8-0.6
BMI without tail0.91.82.6-1.41.41.51.11.3-1.41.51.3-1.51.2-1.1-1.21.6-1.61.0-1.61.6-1.0-1.01.1
Body weight0.52.24.61.4-1.4-1.3-2.2-1.31.3-1.6-1.31.3-1.61.61.6-1.11.1-1.81.1-1.11.71.7-1.8
Weight adjusted by age0.10.10.20.3-0.2-0.2-0.2-0.30.3-0.0-0.30.3-0.40.40.4-0.30.3-0.30.3-0.30.40.4-0.3
Bone surface0.71.32.11.2-1.2-1.2-0.4-1.31.4-0.5-1.31.2-1.31.41.2-1.21.2-1.11.2-1.20.90.9-0.6
Bone volume0.10.20.40.5-0.3-0.30.3-0.70.50.4-0.60.6-0.60.60.5-0.50.5-0.40.5-0.50.30.30.1
Breakpoint value in progressive ratio session0.50.50.90.5-0.4-0.3-0.5-0.80.60.2-0.80.7-0.90.80.9-0.80.8-1.00.8-0.80.90.9-0.8
Number of licking bursts0.10.10.30.1-0.1-0.1-0.10.10.1-0.20.1-0.5-0.10.1-0.00.5-0.5-0.1-0.50.5-0.1-0.1-0.0
Context. condit. distance diff. score0.50.60.90.5-0.6-0.6-0.5-0.80.7-0.3-0.80.9-0.60.70.7-0.90.9-0.70.9-0.90.90.9-0.7
Locomotion velocity, session 10.20.21.10.6-0.6-0.7-0.5-0.20.5-1.0-0.20.2-0.20.30.2-0.20.2-0.20.1-0.10.10.1-0.3
Locomotion distance, session 13.24.14.7-1.82.12.11.82.0-2.11.82.1-2.02.1-2.0-2.12.1-2.12.0-2.22.2-2.0-2.01.7
Locomotion velocity, session 20.50.60.9-0.80.91.00.90.8-0.90.90.8-0.60.8-0.7-0.80.6-0.60.9-0.70.7-0.7-0.70.9
Locomotion distance, session 26.08.310.0-2.83.13.22.82.8-3.12.92.8-2.82.8-2.7-2.92.8-2.83.0-2.82.8-2.9-2.93.0
Locomotion velocity, session 30.10.20.4-0.2-0.0-0.10.20.6-0.1-0.40.6-0.50.6-0.5-0.50.5-0.50.4-0.40.4-0.4-0.40.1
Locomotion distance, session 30.30.30.6-0.80.60.60.20.8-0.70.30.7-0.60.7-0.6-0.60.5-0.50.5-0.60.6-0.3-0.30.4
Stereotopy head waving bouts, day 33.03.54.21.7-1.8-1.7-1.7-1.81.8-1.5-1.81.9-2.02.02.0-2.02.0-1.91.9-1.92.02.0-2.0
Stereotopy head waving duration, day 33.23.84.61.9-1.8-1.8-1.6-1.92.0-1.4-2.02.0-2.12.12.1-2.02.0-1.92.0-2.02.12.1-2.0
Locomotion velocity, session 70.20.20.3-0.40.20.20.50.4-0.20.20.4-0.50.5-0.5-0.50.4-0.40.4-0.40.4-0.5-0.50.4
Locomotion distance, session 72.73.44.7-2.02.02.02.01.7-1.92.21.7-1.81.8-1.8-1.91.7-1.71.8-1.51.5-2.0-2.02.0
Stereotopy head waving bouts, day 74.55.15.62.1-2.3-2.3-2.2-2.12.4-2.2-2.12.3-2.32.32.3-2.32.3-2.32.2-2.22.32.3-2.2
Stereotopy head waving duration, day 76.68.09.02.8-3.0-3.0-2.7-2.73.0-2.8-2.72.9-2.92.82.9-2.92.9-2.82.8-2.82.82.8-2.5
Locomotion velocity, session 80.40.50.80.7-0.9-0.9-0.4-0.70.9-0.7-0.70.7-0.60.70.6-0.70.7-0.60.7-0.70.50.5-0.5
Locomotion distance, session 82.23.24.9-1.92.12.11.91.7-2.02.21.7-1.61.9-1.7-1.81.6-1.61.8-1.61.6-1.5-1.51.7
Degree of sensitization distance2.92.94.6-1.51.71.72.21.4-1.52.11.4-1.61.5-1.6-1.71.6-1.61.6-1.41.4-2.2-2.21.9
Degree of sensitization stereotypy1.82.02.31.3-1.5-1.5-1.4-1.31.5-1.4-1.31.5-1.31.41.4-1.51.5-1.51.3-1.31.41.4-1.3
Conditioned locomotion0.20.30.5-0.50.50.50.50.6-0.40.60.6-0.60.4-0.4-0.50.7-0.70.4-0.70.7-0.5-0.50.2
Cocaine response after cond. corrected0.40.40.90.5-0.6-0.5-0.7-0.60.6-0.5-0.70.4-0.80.80.7-0.60.6-0.70.6-0.60.60.6-0.9
Cocaine response after cond. not corrected0.10.10.30.3-0.3-0.3-0.3-0.30.4-0.3-0.30.2-0.40.40.3-0.30.3-0.30.3-0.30.20.2-0.5
Cocaine response before conditioning0.30.30.8-0.40.30.30.90.5-0.30.30.6-0.30.7-0.7-0.60.5-0.50.8-0.50.5-0.7-0.70.9
Saline control response0.91.22.2-0.80.30.21.01.3-0.5-0.11.3-1.41.3-1.3-1.21.5-1.51.2-1.51.5-0.9-0.90.9
Bone: connectivity density1.01.53.6-1.21.21.11.61.0-1.01.51.0-0.91.0-0.9-1.20.9-0.91.3-0.90.9-1.6-1.61.9
Bone: cortical apparent density0.71.02.2-1.11.41.50.80.8-1.41.30.8-0.80.7-0.7-0.80.7-0.71.0-0.70.7-1.1-1.11.2
Bone: cortical area4.16.18.02.6-2.1-2.0-2.7-2.72.1-2.1-2.62.5-2.52.62.6-2.52.5-2.52.5-2.52.82.8-2.4
Bone: cortical porosity2.32.53.71.9-1.6-1.6-1.4-1.91.6-1.6-1.81.7-1.51.61.5-1.71.7-1.51.6-1.61.31.3-1.2
Bone: cortical porosity3.23.54.82.2-2.0-2.0-1.7-2.12.0-1.8-2.01.9-1.81.91.8-2.02.0-1.81.9-1.91.51.5-1.4
Bone: cortical thickness0.40.62.20.7-0.2-0.1-1.5-0.80.0-0.9-0.80.8-0.80.90.8-0.70.7-0.60.7-0.71.01.0-0.7
Bone: cortical thickness0.10.10.90.4-0.1-0.1-0.9-0.3-0.0-0.6-0.30.3-0.50.50.4-0.30.3-0.40.2-0.20.20.2-0.3
Bone: cortical tissue density0.81.02.3-1.11.41.50.80.8-1.41.40.8-0.80.7-0.8-0.80.7-0.71.0-0.70.7-1.1-1.11.3
Condit. Reinf. active minus inactive responses0.20.20.3-0.50.40.30.60.5-0.30.40.5-0.30.4-0.5-0.40.3-0.30.5-0.50.5-0.6-0.60.5
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.20.20.6-0.1-0.10.6-0.10.3-0.1-0.00.0-0.20.20.20.1-0.1-0.2-0.20.4
Condit. Reinf. active responses1.21.52.2-1.21.00.91.21.5-1.00.81.4-1.21.2-1.3-1.21.2-1.21.2-1.41.4-1.2-1.21.0
Condit. Reinf. inactive responses2.12.53.8-1.51.31.21.31.9-1.40.91.9-1.91.7-1.7-1.71.8-1.81.5-1.91.9-1.3-1.31.1
Incentive salience index mean0.10.10.2-0.30.10.10.40.4-0.10.10.4-0.20.3-0.4-0.30.3-0.30.3-0.40.4-0.3-0.30.3
Condit. Reinf. lever presses0.20.30.6-0.40.40.40.50.7-0.40.30.7-0.80.5-0.6-0.50.8-0.80.5-0.80.8-0.3-0.30.4
Condit. Reinf. active minus inactive responses0.20.30.60.8-0.6-0.7-0.2-0.70.7-0.6-0.50.5-0.30.30.4-0.50.5-0.30.5-0.50.40.4-0.4
Condit. Reinf. active-inactive response ratio0.00.00.20.3-0.4-0.4-0.1-0.20.3-0.4-0.10.1-0.10.10.1-0.10.1-0.10.1-0.10.00.0-0.1
Condit. Reinf. active responses0.00.00.20.10.10.10.4-0.2-0.00.4-0.1-0.10.1-0.1-0.0-0.00.00.1-0.00.0-0.1-0.10.2
Condit. Reinf. inactive responses0.40.51.0-0.70.80.81.00.6-0.71.00.6-0.70.7-0.7-0.70.6-0.60.8-0.60.6-0.6-0.60.8
Condit. Reinf. lever presses0.91.22.1-0.91.11.11.40.9-1.01.41.0-1.21.1-1.1-1.11.1-1.11.1-1.11.1-0.9-0.91.2
Condit. Reinf. lever reinforcers received0.00.00.40.00.30.30.4-0.2-0.10.6-0.1-0.10.1-0.1-0.1-0.00.00.1-0.00.0-0.1-0.10.3
Conditioned reinforcement - actives0.80.81.1-0.91.01.00.80.8-1.01.10.9-0.80.9-0.9-0.90.8-0.80.8-0.90.9-0.8-0.81.0
Conditioned reinforcement - inactives0.30.30.50.5-0.5-0.5-0.6-0.60.5-0.6-0.60.7-0.50.50.5-0.70.7-0.50.7-0.70.50.5-0.3
Conditioned locomotion0.70.81.8-0.91.11.20.90.8-1.11.30.8-0.80.9-0.8-0.80.8-0.80.8-0.80.8-0.8-0.81.0
Patch foraging indifference point 0 sec1.01.72.2-1.31.41.41.41.3-1.41.51.4-1.21.5-1.5-1.31.3-1.31.3-1.31.3-1.0-1.00.8
Patch foraging indifference point AUC3.33.84.8-1.81.71.62.02.0-1.71.42.1-2.02.1-2.1-2.02.1-2.12.0-2.22.2-2.0-2.01.9
Delay disc. indifference point, 0s delay0.70.81.90.9-1.1-1.2-0.9-0.81.0-1.4-0.80.8-0.70.80.8-0.80.8-0.70.8-0.80.80.8-0.8
Delay disc. indifference point, 16s delay0.40.40.6-0.60.50.50.70.6-0.50.60.6-0.80.6-0.6-0.50.7-0.70.5-0.80.8-0.3-0.30.6
Delay disc. indifference point, 2s delay0.20.20.50.7-0.7-0.7-0.4-0.30.6-0.7-0.30.2-0.30.20.4-0.20.2-0.50.2-0.20.50.5-0.5
Delay disc. indifference point, 24s delay0.10.10.1-0.30.20.10.30.3-0.20.10.3-0.40.2-0.2-0.20.4-0.40.3-0.40.4-0.0-0.00.2
Delay disc. indifference point, 4s delay0.70.81.71.0-1.2-1.3-0.8-0.71.1-1.3-0.70.7-0.80.70.8-0.60.6-0.80.6-0.61.01.0-0.8
Delay disc. indifference point, 8s delay2.93.05.11.8-2.2-2.3-1.6-1.52.1-2.2-1.51.5-1.61.61.7-1.41.4-1.71.4-1.41.71.7-1.7
Indifference point function ln k0.71.01.60.8-0.4-0.2-1.1-1.10.4-0.2-1.11.2-1.21.21.1-1.21.2-1.11.3-1.31.01.0-0.9
Indifference point function log k0.71.01.60.8-0.4-0.2-1.1-1.10.4-0.2-1.11.2-1.21.21.1-1.21.2-1.11.3-1.31.01.0-0.9
Patch foraging total patch changes 0 sec1.42.23.1-1.51.71.71.61.5-1.61.81.5-1.41.7-1.7-1.51.4-1.41.5-1.41.4-1.2-1.21.1
Patch foraging total patch changes 12 sec5.87.49.3-2.72.62.62.72.8-2.72.42.9-2.73.1-3.0-2.92.8-2.82.8-2.82.8-2.6-2.62.2
Patch foraging total patch changes 18 sec3.54.46.0-2.01.81.82.32.2-1.82.02.2-2.12.2-2.3-2.12.4-2.42.0-2.42.4-1.8-1.81.7
Patch foraging total patch changes 24 sec0.10.10.2-0.1-0.1-0.20.40.30.1-0.10.3-0.20.5-0.4-0.30.3-0.30.3-0.30.3-0.0-0.0-0.3
Patch foraging total patch changes 6 sec2.63.95.2-2.01.91.91.92.0-1.91.82.0-2.01.9-2.0-1.92.2-2.21.9-2.32.3-1.6-1.61.7
Patch foraging time to switch 0 sec0.30.50.60.5-0.8-0.8-0.7-0.50.8-0.8-0.60.7-0.70.70.7-0.70.7-0.70.7-0.70.70.7-0.5
Patch foraging water rate 0 sec1.11.72.2-1.21.21.21.41.4-1.21.21.4-1.51.5-1.5-1.41.5-1.51.3-1.41.4-1.2-1.20.7
Patch foraging water rate 12 sec0.10.10.4-0.30.50.6-0.2-0.1-0.50.6-0.1-0.1-0.10.10.1-0.00.0-0.10.1-0.10.30.3-0.3
Patch foraging water rate 18 sec0.10.10.6-0.20.50.60.40.0-0.40.80.0-0.30.1-0.1-0.10.2-0.20.2-0.20.2-0.1-0.10.3
Patch foraging water rate 24 sec1.72.33.2-1.51.51.61.51.4-1.41.81.4-1.71.4-1.4-1.41.8-1.81.3-1.71.7-1.3-1.31.1
Patch foraging water rate 6 sec0.00.10.2-0.10.40.5-0.10.1-0.50.30.1-0.30.2-0.2-0.10.3-0.30.2-0.30.3-0.1-0.1-0.2
Seeking ratio, delayed vs. immediate footshock0.30.30.7-0.50.50.40.70.5-0.50.30.5-0.30.7-0.7-0.70.3-0.30.8-0.20.2-0.8-0.80.9
Distance traveled before self-admin0.70.71.60.9-1.1-1.2-0.8-0.61.0-1.3-0.70.9-0.60.70.7-0.90.9-0.70.9-0.90.70.7-0.7
Distance traveled after self-admin0.91.02.3-1.01.11.21.30.8-1.01.50.9-0.81.0-0.8-1.00.9-0.90.9-0.90.9-0.9-0.91.0
Extensor digitorum longus weight1.45.56.5-2.42.52.62.02.5-2.52.42.5-2.42.3-2.4-2.32.4-2.42.1-2.52.5-2.1-2.12.0
Bone: elastic displacement0.91.01.8-1.11.31.30.70.9-1.31.00.9-0.80.9-0.8-1.00.8-0.81.0-0.70.7-1.2-1.20.9
Bone: elastic work0.60.71.30.8-0.5-0.4-1.1-1.00.5-0.6-1.00.9-1.01.00.9-0.90.9-0.81.0-1.00.80.8-0.8
Bone: endosteal estimation1.32.93.71.9-1.6-1.6-1.0-1.91.9-0.6-1.91.8-1.81.71.8-1.71.7-1.91.7-1.71.91.9-1.6
Bone: endosteal perimeter5.010.513.43.5-3.4-3.4-2.5-3.43.7-2.5-3.43.2-3.43.43.3-3.13.1-3.43.1-3.13.23.2-3.1
Epididymis fat weight0.10.30.90.3-0.3-0.2-0.9-0.50.3-0.2-0.50.5-0.60.70.6-0.30.3-0.80.4-0.40.70.7-0.9
Delta time in closed arm before/after self-admin0.30.30.60.3-0.7-0.8-0.3-0.40.8-0.6-0.40.5-0.40.40.5-0.50.5-0.50.4-0.40.50.5-0.6
Delta time in open arm before/after self-admin1.71.62.1-1.21.21.21.21.3-1.31.01.3-1.31.3-1.3-1.31.3-1.31.3-1.21.2-1.3-1.31.5
Diff in mean of infusions in LGA sessions1.21.42.11.1-1.0-0.9-1.0-1.21.2-0.4-1.21.0-1.41.31.3-1.01.0-1.41.1-1.11.41.4-1.2
Delay discount exponential model param0.91.01.9-1.11.31.40.90.8-1.31.40.8-0.70.9-0.8-0.90.7-0.71.0-0.70.7-1.1-1.11.0
Extinction: sum of active levers before priming0.10.10.20.3-0.00.0-0.3-0.40.0-0.0-0.30.2-0.30.30.2-0.10.1-0.20.1-0.10.30.3-0.3
Active lever presses in extinction session 60.10.10.3-0.20.20.30.10.1-0.20.50.1-0.2-0.1-0.00.10.3-0.3-0.1-0.30.30.10.1-0.2
Bone: final force1.82.94.01.7-1.5-1.4-1.8-1.81.4-1.5-1.81.8-1.81.81.8-1.71.7-1.61.7-1.72.02.0-1.4
Bone: final moment2.13.34.71.8-1.6-1.5-1.8-2.01.5-1.5-1.91.9-1.92.02.0-1.91.9-1.71.8-1.82.22.2-1.5
Food consumed during 24 hour testing period0.20.20.7-0.3-0.0-0.10.60.50.0-0.00.5-0.80.4-0.4-0.40.7-0.70.4-0.70.7-0.4-0.40.3
Glucose0.10.10.30.3-0.2-0.1-0.6-0.60.2-0.1-0.50.3-0.60.60.4-0.30.3-0.50.3-0.30.10.10.1
Heart weight0.50.71.40.6-0.4-0.3-1.2-0.80.4-0.5-0.80.9-0.80.90.9-0.90.9-1.00.9-0.90.90.9-0.8
Delay discount hyperbolic model param0.80.91.7-1.11.21.30.80.7-1.21.30.7-0.70.8-0.8-0.90.6-0.60.9-0.60.6-1.0-1.01.0
Intermittent access intake day 1-15 change0.00.00.4-0.1-0.3-0.4-0.00.20.2-0.60.1-0.00.2-0.2-0.20.0-0.00.1-0.00.0-0.2-0.20.2
Intermittent access intake escalation0.10.10.2-0.3-0.1-0.20.30.40.0-0.30.3-0.20.4-0.4-0.40.2-0.20.3-0.20.2-0.4-0.40.4
Intermittent access intake escalation 20.50.50.7-0.80.40.30.70.9-0.50.20.8-0.80.8-0.8-0.80.7-0.70.7-0.80.8-0.8-0.80.8
Intermitt. access day 1 inactive lever presses2.52.73.11.7-1.7-1.7-1.5-1.71.7-1.6-1.71.8-1.61.71.6-1.81.8-1.51.7-1.71.51.5-1.4
Intermitt. access day 15 inactive lever presses0.50.60.7-0.70.60.60.80.8-0.70.50.8-0.80.8-0.8-0.80.8-0.80.8-0.80.8-0.8-0.80.8
Intermitt. access escalation Index0.60.61.00.8-0.9-1.0-0.5-0.71.0-0.8-0.70.6-0.70.80.7-0.70.7-0.70.7-0.70.70.7-0.7
Intermittent access day 1 total infusions0.40.50.70.6-0.4-0.3-0.7-0.80.4-0.1-0.80.7-0.80.80.8-0.70.7-0.80.7-0.70.80.8-0.7
Intermittent access day 15 total infusions0.00.00.10.0-0.2-0.2-0.1-0.10.2-0.1-0.10.2-0.10.10.1-0.30.3-0.10.2-0.20.10.1-0.0
Intermittent access terminal intake (last 3 days)0.20.30.30.4-0.5-0.5-0.5-0.50.6-0.4-0.50.6-0.50.50.5-0.60.6-0.60.5-0.50.50.5-0.4
Intermittent access total infusions0.30.40.50.5-0.5-0.4-0.6-0.70.5-0.3-0.70.7-0.70.60.7-0.70.7-0.70.7-0.70.70.7-0.5
Intermittent access day 1 locomotion0.20.20.8-0.50.70.70.50.3-0.60.90.3-0.30.3-0.3-0.30.3-0.30.3-0.40.4-0.3-0.30.5
Intermittent access day 15 total locomotion0.20.20.40.4-0.2-0.2-0.5-0.40.2-0.2-0.40.6-0.40.40.4-0.60.6-0.40.6-0.60.40.4-0.3
Intermittent access total locomotion0.10.10.4-0.30.50.50.20.2-0.40.60.2-0.10.2-0.2-0.20.1-0.10.2-0.20.2-0.2-0.20.4
Intermittent access standard deviation4.75.05.82.2-2.3-2.3-2.4-2.12.3-2.4-2.22.2-2.22.22.2-2.22.2-2.32.2-2.22.22.2-2.1
Left kidney weight3.49.511.33.1-3.1-3.1-3.4-3.03.1-3.2-3.03.0-3.13.13.1-2.92.9-3.22.9-2.93.23.2-3.3
Right kidney weight1.23.44.52.0-1.8-1.7-2.1-1.91.7-2.0-1.81.9-1.81.91.8-1.81.8-1.81.8-1.81.71.7-2.0
Cocaine induced anxiety0.20.20.70.4-0.7-0.8-0.3-0.40.7-0.9-0.40.4-0.40.40.4-0.40.4-0.30.4-0.40.40.4-0.2
Post-drug Anxiety0.20.20.4-0.40.10.00.50.5-0.10.00.5-0.60.5-0.5-0.50.6-0.60.5-0.50.5-0.5-0.50.2
Baseline Anxiety0.00.00.1-0.10.20.2-0.00.1-0.20.20.1-0.10.1-0.1-0.10.1-0.10.0-0.10.1-0.1-0.1-0.1
Tail length0.41.32.1-1.00.60.51.21.3-0.60.71.2-1.51.1-1.1-1.21.4-1.41.0-1.31.3-1.1-1.10.9
Length with tail0.83.04.81.8-2.1-2.1-1.9-1.42.0-2.2-1.51.4-1.71.71.7-1.41.4-1.81.5-1.51.71.7-1.9
Length without tail4.59.811.93.1-3.0-3.0-3.4-3.02.9-3.2-3.03.2-3.23.13.2-3.13.1-3.13.1-3.13.13.1-3.2
Times rat made contact with spout0.40.50.9-0.70.60.50.70.7-0.50.60.7-1.00.6-0.6-0.70.8-0.80.7-0.80.8-0.5-0.50.7
Lifetime Intake0.50.60.80.6-0.6-0.5-0.8-0.90.6-0.4-0.90.9-0.90.80.9-0.90.9-0.80.8-0.80.80.8-0.7
Liver weight, left3.55.76.32.3-2.4-2.4-2.4-2.42.4-2.3-2.42.3-2.52.52.5-2.32.3-2.42.3-2.32.42.4-2.2
Liver weight, right0.81.32.21.3-1.3-1.3-1.5-1.11.2-1.5-1.10.9-1.11.11.1-0.90.9-1.30.9-0.91.11.1-1.2
Locomotor activity0.00.00.00.20.10.20.1-0.0-0.10.2-0.00.00.00.0-0.0-0.10.10.10.1-0.1-0.1-0.10.1
Locomotor testing distance0.10.20.50.5-0.2-0.2-0.1-0.50.30.2-0.60.7-0.60.60.5-0.70.7-0.40.7-0.70.30.3-0.2
Locomotor testing rearing1.01.52.3-1.11.31.21.51.2-1.21.31.2-1.01.3-1.3-1.21.0-1.01.3-1.01.0-1.4-1.41.4
Locomotion in novel chamber0.70.91.5-0.90.60.61.20.9-0.60.81.0-1.00.9-0.9-0.91.0-1.00.9-1.11.1-1.0-1.01.0
Locomotion in novel chamber post-restriction0.20.30.40.4-0.5-0.5-0.2-0.60.6-0.2-0.60.6-0.60.60.6-0.60.6-0.50.5-0.50.50.5-0.5
Fecal boli incidents, locomotor time 10.10.10.8-0.20.50.60.30.1-0.40.90.1-0.10.1-0.1-0.10.1-0.10.1-0.20.2-0.1-0.10.3
Change in fecal boli incidents, locomotor task0.10.10.1-0.20.30.30.10.3-0.30.30.3-0.30.3-0.3-0.30.2-0.20.2-0.20.2-0.3-0.30.2
Time >=10cm from walls, locomotor time 10.00.00.10.1-0.3-0.30.2-0.10.3-0.2-0.10.2-0.10.10.0-0.20.2-0.00.2-0.2-0.1-0.10.2
Bouts of movement, locomotor time 10.00.00.10.00.20.2-0.20.0-0.20.00.00.00.0-0.0-0.10.1-0.10.0-0.00.0-0.4-0.40.1
Total resting periods, locomotor time 10.00.00.2-0.10.30.3-0.00.1-0.30.10.1-0.00.1-0.1-0.20.1-0.10.1-0.10.1-0.4-0.40.3
Rest time, locomotor task time 10.50.60.90.7-0.5-0.4-0.9-0.80.5-0.5-0.80.9-0.90.80.8-0.90.9-0.80.9-0.90.60.6-0.5
Distance moved, locomotor task time 10.50.50.8-0.70.50.40.90.8-0.50.40.8-0.80.9-0.8-0.70.8-0.80.8-0.80.8-0.4-0.40.5
Vertical activity count, locomotor time 12.42.53.3-1.61.31.31.61.8-1.41.21.8-1.81.8-1.8-1.61.8-1.81.5-1.81.8-1.3-1.31.1
Time >=10cm from walls, locomotor time 20.30.40.9-0.60.60.60.60.5-0.70.40.5-0.50.5-0.5-0.60.5-0.50.7-0.50.5-0.8-0.80.9
Bouts of movement, locomotor time 20.40.50.70.7-0.6-0.6-0.6-0.80.6-0.4-0.80.8-0.80.80.7-0.80.8-0.70.8-0.80.60.6-0.4
Total resting periods, locomotor time 20.50.60.80.7-0.6-0.6-0.6-0.90.7-0.3-0.90.9-0.80.90.8-0.90.9-0.80.9-0.90.60.6-0.4
Rest time, locomotor task time 21.31.52.11.3-1.0-0.9-1.1-1.41.1-0.6-1.41.5-1.41.31.3-1.41.4-1.41.4-1.41.01.0-1.0
Distance moved, locomotor task time 20.40.50.8-0.80.60.60.50.8-0.80.20.8-0.90.9-0.8-0.70.8-0.80.9-0.80.8-0.5-0.50.4
Vertical activity count, locomotor time 20.40.50.8-0.70.70.60.40.9-0.70.40.8-0.90.8-0.8-0.60.8-0.80.6-0.70.7-0.5-0.50.1
Light reinforcement 12.85.15.9-2.32.22.22.12.4-2.31.92.4-2.42.4-2.4-2.32.4-2.42.2-2.42.4-2.0-2.01.7
Light reinforcement 20.60.81.2-1.00.60.50.61.1-0.70.21.1-1.11.0-1.0-1.01.1-1.10.9-1.11.1-0.7-0.70.2
Bone: marrow area1.43.13.91.9-1.7-1.6-1.0-1.92.0-0.7-1.91.8-1.81.71.8-1.81.8-1.91.7-1.72.02.0-1.7
Bone: maximum diameter9.016.518.44.3-4.0-3.9-3.7-4.34.1-3.4-4.34.1-4.24.24.1-4.14.1-4.24.1-4.14.14.1-3.8
Bone: maximum force2.34.05.52.0-1.6-1.5-2.0-2.31.7-1.4-2.22.1-2.12.22.1-2.02.0-2.02.0-2.02.32.3-1.8
Bone: maximum moment2.64.46.12.0-1.7-1.5-2.0-2.41.7-1.4-2.32.2-2.22.32.2-2.22.2-2.02.2-2.22.52.5-1.9
Mean time between licks in bursts0.00.10.20.1-0.1-0.0-0.1-0.20.1-0.1-0.20.3-0.20.20.1-0.30.3-0.10.3-0.3-0.4-0.40.3
Mean num. licks in bursts0.30.40.9-0.70.80.80.80.6-0.80.90.6-0.30.7-0.7-0.60.3-0.30.7-0.30.3-0.4-0.40.7
Cd content in liver0.40.41.1-0.71.01.00.40.5-1.00.90.5-0.60.5-0.5-0.50.6-0.60.6-0.50.5-0.4-0.40.9
Co content in liver0.20.20.8-0.50.70.80.50.1-0.70.90.2-0.20.4-0.4-0.30.2-0.20.5-0.20.2-0.4-0.40.5
Cu content in liver0.00.00.20.2-0.0-0.0-0.2-0.1-0.0-0.1-0.10.0-0.00.10.0-0.00.0-0.00.0-0.00.10.1-0.4
Fe content in liver0.00.00.20.3-0.4-0.40.1-0.20.4-0.2-0.10.1-0.10.20.1-0.10.1-0.20.1-0.10.20.2-0.2
K content in liver0.00.00.2-0.10.10.00.40.1-0.10.00.1-0.10.3-0.3-0.20.0-0.00.40.0-0.0-0.3-0.30.1
Mg content in liver1.51.52.2-1.31.41.41.51.1-1.31.41.1-1.11.2-1.1-1.21.0-1.01.4-1.01.0-1.3-1.31.4
Mn content in liver0.50.51.20.6-1.0-1.0-0.8-0.51.0-1.1-0.50.5-0.80.70.8-0.50.5-0.70.5-0.50.50.5-0.9
Na content in liver0.30.30.50.5-0.7-0.7-0.3-0.50.6-0.7-0.50.6-0.50.50.6-0.60.6-0.30.6-0.60.50.5-0.5
Rb content in liver3.13.94.7-2.02.02.01.91.9-2.01.91.9-1.91.9-1.9-2.01.9-1.92.0-1.91.9-2.2-2.22.1
Se content in liver0.81.01.5-1.00.70.61.21.2-0.70.61.2-1.11.0-1.1-1.01.1-1.11.1-1.11.1-1.0-1.01.0
Sr content in liver0.10.10.20.2-0.2-0.1-0.4-0.30.1-0.3-0.30.4-0.30.30.4-0.40.4-0.20.4-0.40.50.5-0.4
Zn content in liver2.02.22.81.7-1.3-1.3-1.4-1.71.3-1.3-1.61.6-1.41.51.5-1.61.6-1.31.6-1.61.51.5-1.4
Bone: minimum diameter3.56.68.52.9-2.4-2.3-2.0-2.92.5-1.9-2.82.8-2.52.52.6-2.72.7-2.42.8-2.82.72.7-2.3
Time in familiar zone, hab. session 10.10.10.3-0.30.30.30.30.4-0.40.20.4-0.30.5-0.5-0.40.1-0.10.3-0.20.2-0.5-0.50.2
Time in novel zone, hab. session 10.30.30.50.5-0.7-0.7-0.5-0.60.7-0.7-0.60.5-0.60.60.5-0.40.4-0.50.5-0.50.40.4-0.3
Total zone transitions, hab. session 12.13.03.5-1.71.81.91.81.7-1.81.81.7-1.61.6-1.5-1.71.6-1.61.8-1.71.7-1.7-1.71.8
Total locomotion distance, hab. session 12.12.93.6-1.81.81.81.71.9-1.81.71.8-1.81.7-1.7-1.71.6-1.61.7-1.71.7-1.6-1.61.5
Locomotion velocity, hab. session 12.73.84.4-1.92.12.11.92.1-2.11.92.0-2.01.9-2.0-1.91.9-1.92.0-2.02.0-1.7-1.71.7
Time in familiar zone, hab. session 20.00.00.1-0.40.30.30.10.1-0.20.30.1-0.10.2-0.2-0.10.1-0.10.1-0.00.0-0.0-0.0-0.1
Time in novel zone, hab. session 20.50.50.70.8-0.7-0.7-0.6-0.80.7-0.6-0.80.8-0.80.80.7-0.80.8-0.60.8-0.80.70.7-0.4
Total zone transitions, hab. session 25.77.39.7-2.73.03.12.82.6-3.03.12.6-2.52.7-2.5-2.72.4-2.42.8-2.52.5-2.7-2.72.7
Total locomotion distance, hab. session 26.18.19.7-3.03.13.12.73.0-3.13.02.9-2.92.8-2.8-2.82.7-2.72.8-2.82.8-2.7-2.72.5
Locomotion velocity, hab. session 26.48.710.0-3.13.13.22.83.1-3.23.03.0-3.12.9-2.9-2.92.9-2.92.9-2.92.9-2.8-2.82.5
Novel to familiar place preference ratio1.41.43.2-1.11.51.61.40.8-1.41.80.9-0.81.2-1.1-1.10.9-0.91.2-0.80.8-1.1-1.11.4
Novelty place preference1.01.02.4-0.91.31.31.20.6-1.21.50.7-0.61.0-0.9-1.00.8-0.81.0-0.70.7-1.0-1.01.2
Time in novel zone, NPP test1.31.32.8-1.11.41.51.40.8-1.41.70.8-0.81.1-1.1-1.10.9-0.91.2-0.80.8-1.1-1.11.4
Total zone transitions, NPP test5.07.17.9-2.72.82.82.72.7-2.82.72.7-2.72.7-2.7-2.62.6-2.62.7-2.72.7-2.5-2.52.3
Total locomotion distance, NPP test8.611.713.6-3.53.73.73.23.6-3.73.43.5-3.63.4-3.4-3.43.4-3.43.4-3.53.5-3.1-3.12.9
Locomotion velocity, NPP test7.210.311.9-3.33.43.43.03.4-3.43.23.3-3.33.2-3.2-3.13.2-3.23.1-3.33.3-3.0-3.02.7
Intraocular pressure0.30.51.4-0.70.70.70.80.6-0.61.20.6-0.70.5-0.6-0.60.7-0.70.3-0.70.7-0.7-0.70.4
Delta distance traveled before/after self-admin2.32.44.6-1.61.81.91.71.2-1.72.11.3-1.41.4-1.3-1.51.5-1.51.5-1.51.5-1.4-1.41.6
Delta ambulatory time before/after self-admin2.42.75.2-1.71.92.01.81.3-1.82.31.4-1.51.4-1.4-1.51.6-1.61.5-1.61.6-1.4-1.41.7
Parametrial fat weight0.00.00.3-0.00.00.0-0.20.1-0.0-0.10.0-0.10.1-0.20.10.0-0.0-0.10.0-0.00.40.4-0.6
Pavlov. Cond. lever latency0.20.20.8-0.70.50.50.70.2-0.40.90.2-0.20.4-0.4-0.40.2-0.20.4-0.10.1-0.5-0.50.7
Pavlov. Cond. magazine entry latency1.82.33.31.8-1.8-1.8-1.5-1.51.7-1.8-1.51.4-1.51.51.5-1.31.3-1.51.3-1.31.41.4-1.6
Pavlov. Cond. change in total contacts0.10.10.30.10.40.50.1-0.1-0.40.4-0.0-0.0-0.0-0.0-0.10.1-0.10.2-0.10.1-0.2-0.20.3
Pavlov. Cond. index score1.01.32.11.4-1.3-1.3-1.3-1.01.2-1.5-1.00.9-1.21.11.2-0.90.9-1.10.7-0.71.21.2-1.4
Pavlov. Cond. latency score1.31.62.91.5-1.5-1.5-1.5-1.11.4-1.7-1.11.0-1.31.21.3-1.01.0-1.30.8-0.81.31.3-1.6
Pavlov. Cond. lever contacts0.00.00.10.3-0.1-0.1-0.40.00.0-0.40.0-0.1-0.10.10.10.1-0.1-0.1-0.30.30.20.2-0.3
Pavlov. Cond. magazine entry number3.13.94.8-2.22.12.12.02.0-2.12.11.9-1.92.1-2.0-2.01.8-1.82.0-1.71.7-1.9-1.92.0
Pavlov. Cond. intertrial magazine entries2.12.53.8-1.71.71.61.71.6-1.61.71.5-1.41.5-1.6-1.61.4-1.41.6-1.51.5-1.6-1.61.9
Pavlov. Cond. lever-magazine prob. diff.0.70.91.51.2-1.1-1.1-1.0-0.91.0-1.2-0.80.8-1.00.91.0-0.70.7-0.90.6-0.61.01.0-1.1
Pavlov. Cond. response bias1.31.62.41.5-1.3-1.3-1.3-1.31.3-1.4-1.21.2-1.31.31.3-1.11.1-1.21.0-1.01.31.3-1.3
Pavlov. Cond. lever latency0.81.02.30.9-1.1-1.1-1.4-0.91.0-1.5-0.90.9-0.90.90.9-0.90.9-0.90.9-0.90.80.8-1.2
Pavlov. Cond. magazine entry latency0.10.10.6-0.30.50.50.20.1-0.40.80.1-0.00.1-0.1-0.10.1-0.1-0.0-0.10.10.10.10.2
Pavlov. Cond. change in total contacts0.50.71.8-0.81.01.01.00.6-0.91.40.7-0.60.7-0.7-0.70.7-0.70.6-0.70.7-0.8-0.81.0
Pavlov. Cond. index score0.40.51.5-0.60.80.90.90.6-0.71.20.6-0.60.6-0.6-0.60.6-0.60.5-0.60.6-0.5-0.50.9
Pavlov. Cond. latency score0.20.20.9-0.40.60.60.70.4-0.40.90.4-0.30.4-0.4-0.40.4-0.40.3-0.40.4-0.2-0.20.6
Pavlov. Cond. lever contacts1.11.52.6-1.01.21.21.61.2-1.11.51.2-1.11.2-1.2-1.21.1-1.11.2-1.11.1-1.1-1.11.4
Pavlov. Cond. magazine entry number0.40.51.40.7-0.9-0.9-0.7-0.60.8-1.2-0.60.6-0.60.60.6-0.60.6-0.50.6-0.60.40.4-0.7
Pavlov. Cond. intertrial magazine entries0.40.51.2-0.50.30.21.10.8-0.30.40.8-0.80.9-0.9-0.70.8-0.80.9-0.80.8-0.5-0.50.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.6-0.70.90.91.00.7-0.81.30.7-0.60.7-0.7-0.70.7-0.70.6-0.70.7-0.6-0.60.9
Pavlov. Cond. response bias0.71.01.8-0.91.11.11.21.0-1.01.31.0-0.91.0-1.0-0.90.9-0.90.9-0.90.9-0.7-0.71.1
Time in closed arm before self-admin0.00.00.1-0.00.20.2-0.10.1-0.3-0.00.1-0.20.1-0.2-0.10.1-0.10.1-0.10.1-0.1-0.10.2
Time in closed arm after self-admin3.03.13.41.7-1.7-1.7-1.7-1.71.7-1.5-1.71.8-1.71.71.8-1.81.8-1.81.8-1.81.81.8-1.7
Time in open arm before self-admin0.50.60.80.8-0.7-0.7-0.7-0.90.7-0.6-0.80.8-0.70.90.7-0.80.8-0.70.7-0.70.70.7-0.8
Time in open arm after self-admin0.70.70.9-0.80.80.80.90.7-0.80.90.8-0.80.9-0.8-0.90.9-0.90.9-0.90.9-0.9-0.90.9
Bone: periosteal estimation3.77.69.62.9-2.5-2.4-2.4-3.02.7-1.9-3.02.8-2.82.82.9-2.82.8-2.92.8-2.83.13.1-2.6
Bone: periosteal perimeter7.211.913.23.6-3.4-3.3-3.4-3.63.4-3.1-3.63.4-3.53.63.5-3.43.4-3.53.4-3.43.63.6-3.4
Bone: post-yield work0.10.21.0-0.30.60.70.6-0.0-0.51.00.0-0.00.1-0.1-0.10.1-0.10.3-0.10.10.00.00.6
Progressive ratio test 1 active lever presses0.00.00.2-0.20.20.20.30.0-0.10.40.00.00.0-0.1-0.0-0.00.00.1-0.00.0-0.1-0.10.2
Progressive ratio test 1 breakpoint0.00.00.1-0.10.10.10.1-0.1-0.00.3-0.10.2-0.10.10.1-0.20.2-0.10.1-0.10.10.10.0
Progressive ratio test 1 inactive lever presses0.20.20.30.5-0.5-0.5-0.4-0.50.5-0.6-0.40.5-0.40.40.4-0.50.5-0.40.5-0.50.40.4-0.3
Progressive ratio test 2 active lever presses0.00.00.3-0.20.30.30.1-0.0-0.20.50.00.00.0-0.0-0.0-0.00.0-0.0-0.00.0-0.0-0.00.1
Progressive ratio test 2 breakpoint0.10.10.3-0.30.40.40.20.1-0.30.60.1-0.10.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.10.3
Progressive ratio test 2 inactive lever presses0.00.00.00.1-0.1-0.1-0.2-0.20.1-0.1-0.20.2-0.20.10.1-0.20.2-0.10.2-0.20.10.10.1
Incentive Sensitization - Responses0.70.71.10.9-0.7-0.7-1.0-0.90.7-0.8-0.90.8-0.90.90.9-0.80.8-0.90.8-0.80.90.9-0.9
Incentive Sensitization - Breakpoint1.01.01.41.1-0.9-0.9-1.2-1.00.9-0.9-1.01.0-1.01.01.0-0.90.9-1.10.9-0.91.11.1-1.0
Sum of active levers in priming session hrs 5-60.70.61.21.0-0.6-0.5-0.6-1.10.7-0.2-1.01.0-0.80.90.8-0.80.8-0.90.7-0.70.80.8-0.7
Progressive ratio0.20.20.40.4-0.1-0.1-0.4-0.40.20.2-0.50.5-0.60.50.5-0.60.6-0.60.5-0.50.40.4-0.6
Food seeking constrained by brief footshock0.81.01.31.2-0.9-0.9-1.1-1.00.9-0.9-1.01.0-1.01.01.0-1.01.0-1.11.0-1.00.90.9-1.1
Seeking ratio, punishment vs. effort0.10.10.50.4-0.5-0.5-0.2-0.20.4-0.7-0.20.1-0.10.20.1-0.10.1-0.10.2-0.20.20.2-0.2
Retroperitoneal fat weight0.31.12.50.9-1.2-1.2-1.3-0.81.2-1.1-0.80.8-0.90.91.0-0.70.7-1.40.7-0.71.21.2-1.6
Reaction time number correct4.26.17.9-2.62.32.22.52.5-2.22.42.5-2.62.3-2.3-2.42.8-2.82.3-2.82.8-2.2-2.22.2
Reaction time mean minus median0.50.61.20.8-0.8-0.8-1.0-0.70.7-1.1-0.80.8-0.70.70.7-0.80.8-0.70.9-0.90.80.8-0.8
Reaction time mean minus median AUC0.60.81.71.0-1.0-1.1-1.0-0.80.9-1.3-0.80.9-0.80.80.8-0.80.8-0.70.9-0.90.80.8-1.0
Reaction time num false alarms0.10.10.3-0.20.40.40.40.4-0.40.40.4-0.20.6-0.6-0.40.3-0.30.3-0.30.3-0.4-0.40.1
Reaction time num false alarms AUC0.20.30.6-0.50.60.70.60.6-0.60.80.6-0.30.7-0.7-0.60.4-0.40.5-0.40.4-0.6-0.60.3
Reaction time trials correct on left4.26.17.9-2.62.32.22.52.5-2.22.42.5-2.62.3-2.3-2.42.8-2.82.3-2.82.8-2.2-2.22.2
Reaction time trials on left4.25.97.8-2.62.32.22.52.5-2.22.42.5-2.62.3-2.3-2.32.8-2.82.3-2.72.7-2.2-2.22.2
Reaction time mean0.10.20.40.5-0.3-0.2-0.4-0.50.2-0.3-0.50.5-0.40.40.3-0.60.6-0.30.6-0.60.10.1-0.1
Reaction time mean AUC0.10.10.20.3-0.0-0.0-0.3-0.30.0-0.1-0.30.3-0.20.20.1-0.40.4-0.20.4-0.4-0.0-0.0-0.0
Median of all reaction times0.10.10.30.5-0.2-0.1-0.2-0.50.2-0.1-0.50.4-0.30.30.2-0.50.5-0.20.5-0.5-0.1-0.10.1
Reaction time omissions0.40.61.20.7-0.9-0.9-0.8-0.60.8-1.0-0.60.7-0.60.60.7-0.70.7-0.70.7-0.70.80.8-1.1
Reaction time false alarm rate0.40.51.00.9-0.6-0.5-0.7-0.70.6-0.5-0.70.9-0.50.50.6-1.01.0-0.71.0-1.00.50.5-0.8
Reaction time premature initiation rate2.02.64.2-1.72.02.11.51.5-1.92.01.4-1.61.4-1.4-1.51.4-1.41.6-1.51.5-1.5-1.51.8
Reaction time premature initiations5.07.19.9-2.83.03.02.72.5-2.93.12.5-2.62.4-2.4-2.52.6-2.62.6-2.62.6-2.4-2.42.7
Std. dev. reaction times0.10.10.20.4-0.2-0.2-0.5-0.40.2-0.4-0.40.4-0.30.30.3-0.40.4-0.30.4-0.40.30.3-0.3
Reaction time trials completed4.25.97.8-2.62.32.22.52.5-2.22.42.5-2.62.3-2.3-2.32.8-2.82.3-2.72.7-2.2-2.22.2
Reaction time trials AUC4.97.09.0-2.82.52.42.72.7-2.42.62.7-2.82.5-2.5-2.63.0-3.02.5-3.03.0-2.4-2.42.4
Run reversals in cocaine runway, females0.10.10.40.3-0.2-0.2-0.30.10.2-0.30.0-0.2-0.1-0.00.10.1-0.1-0.3-0.00.00.20.2-0.6
Run reversals in cocaine runway, males0.20.10.60.3-0.1-0.0-0.7-0.40.1-0.1-0.40.4-0.40.30.4-0.30.3-0.50.3-0.30.40.4-0.8
Latency to leave start box in cocaine runway0.10.10.4-0.40.60.60.30.1-0.50.70.2-0.00.3-0.2-0.2-0.00.00.2-0.10.1-0.3-0.30.2
Latency to leave start box in cocaine runway, F0.50.50.8-0.90.80.80.70.7-0.80.80.7-0.60.8-0.7-0.70.5-0.50.8-0.60.6-0.7-0.70.6
Latency to leave start box in cocaine runway, M0.30.31.0-0.60.80.90.40.4-0.81.00.4-0.30.4-0.3-0.40.3-0.30.4-0.40.4-0.4-0.40.6
Std. dev. time between licks in bursts2.22.73.1-1.61.51.41.81.7-1.51.51.7-1.71.7-1.7-1.71.7-1.71.6-1.71.7-1.7-1.71.5
Total sessions with >9 infusions1.71.92.21.2-1.1-1.1-1.4-1.51.2-1.0-1.51.5-1.51.51.5-1.51.5-1.41.4-1.41.51.5-1.3
Short access day 1 total inactive lever presses0.70.71.00.7-0.7-0.7-0.8-0.90.8-0.6-0.91.0-1.00.90.9-1.01.0-0.81.0-1.00.80.8-0.8
Short access day 10 total inactive lever presses0.70.81.40.9-1.0-1.1-0.8-0.91.0-1.2-0.91.0-0.80.80.8-1.01.0-0.71.0-1.00.70.7-0.7
Short access day 1 total infusions1.92.02.41.3-1.2-1.2-1.5-1.51.3-1.1-1.51.4-1.61.51.5-1.41.4-1.41.3-1.31.61.6-1.4
Short access day 10 total infusions2.42.63.11.5-1.4-1.4-1.5-1.71.5-1.1-1.71.7-1.81.71.8-1.71.7-1.71.6-1.61.81.8-1.6
Short access total infusions0.60.70.90.7-0.6-0.5-0.9-0.90.6-0.4-0.90.9-1.00.90.9-0.90.9-0.90.8-0.80.90.9-0.9
Short access day 1 locomotion0.50.50.70.7-0.6-0.6-0.8-0.70.6-0.6-0.80.7-0.80.80.8-0.70.7-0.70.7-0.70.80.8-0.7
Short access day 10 total locomotion0.60.60.80.7-0.6-0.6-0.9-0.80.6-0.6-0.80.9-0.80.80.9-0.90.9-0.80.8-0.80.90.9-0.7
Short access total locomotion1.51.52.21.1-0.9-0.9-1.5-1.30.9-1.0-1.31.3-1.31.31.3-1.31.3-1.21.2-1.21.31.3-1.2
One hour access (0.3 mA shock)0.00.10.3-0.30.30.30.20.1-0.20.60.1-0.20.1-0.1-0.10.2-0.20.0-0.20.2-0.1-0.10.2
Compulsive drug intake0.40.40.7-0.60.80.90.50.6-0.80.70.6-0.60.7-0.6-0.60.6-0.60.6-0.60.6-0.6-0.60.6
One hour access (shock baseline)0.00.00.10.1-0.2-0.20.0-0.10.3-0.0-0.10.1-0.10.10.1-0.10.1-0.20.1-0.10.10.1-0.0
Social response proportion0.50.50.8-0.50.80.80.40.7-0.80.70.7-0.90.7-0.7-0.70.9-0.90.5-0.90.9-0.6-0.60.7
Social responses0.40.51.0-0.50.50.50.50.8-0.60.20.8-1.00.7-0.7-0.71.0-1.00.7-1.01.0-0.6-0.60.8
Social time0.60.81.2-0.91.01.00.61.0-1.10.81.0-1.01.0-1.0-0.90.9-0.90.8-0.80.8-0.7-0.70.7
Soleus weight0.92.53.6-1.71.61.61.11.9-1.71.21.8-1.91.5-1.6-1.51.8-1.81.5-1.91.9-0.9-0.91.4
Bone: stiffness2.13.44.32.0-1.7-1.6-1.9-2.11.6-1.6-2.01.8-1.91.91.9-1.81.8-1.81.8-1.82.02.0-1.5
Tibialis anterior weight0.10.40.6-0.60.80.80.40.7-0.80.70.6-0.60.5-0.6-0.50.7-0.70.5-0.70.7-0.3-0.30.6
Time to tail flick, vehicle, before self-admin1.21.21.6-0.91.11.00.91.0-1.20.71.1-1.31.2-1.1-1.21.1-1.11.2-1.21.2-1.2-1.21.1
Time to tail flick, vehicle, after self-admin1.82.03.01.3-1.2-1.1-1.7-1.41.1-1.3-1.41.5-1.51.41.5-1.41.4-1.51.5-1.51.51.5-1.4
Time to tail flick, test, before self-admin0.50.50.8-0.50.60.50.90.7-0.60.50.7-0.70.8-0.9-0.80.6-0.60.8-0.60.6-0.8-0.80.7
Time to tail flick, test, after self-admin0.80.81.00.9-0.9-0.9-1.0-1.00.9-0.9-0.90.8-0.90.90.9-0.80.8-1.00.7-0.70.90.9-1.0
Delta time to tail flick, vehicle, before/after SA0.50.50.80.5-0.5-0.5-0.7-0.60.6-0.3-0.70.9-0.80.70.8-0.80.8-0.80.8-0.80.80.8-0.8
Delta time to tail flick, test, before/after SA1.81.62.51.1-1.2-1.2-1.6-1.21.2-1.3-1.21.1-1.41.51.3-1.01.0-1.41.0-1.01.41.4-1.4
Tibia length11.031.142.95.7-6.2-6.3-6.0-5.26.0-6.5-5.25.2-5.35.25.4-5.15.1-5.65.2-5.25.55.5-5.8
Ambulatory time before self-admin1.11.12.61.2-1.3-1.4-1.1-0.81.2-1.6-0.91.0-0.80.80.9-1.01.0-0.91.1-1.10.90.9-1.0
Ambulatory time after self-admin0.20.20.8-0.50.60.60.70.3-0.50.90.3-0.30.4-0.3-0.40.4-0.40.4-0.40.4-0.3-0.30.4
Bone: tissue strength0.20.20.9-0.40.70.80.4-0.1-0.61.0-0.00.20.2-0.1-0.2-0.10.10.30.1-0.1-0.0-0.00.3
Total heroin consumption4.14.85.52.1-2.0-2.0-2.0-2.42.1-1.7-2.32.3-2.32.32.3-2.32.3-2.22.3-2.32.32.3-2.2
Bone: trabecular number0.20.31.1-0.50.50.50.90.4-0.40.70.4-0.50.4-0.4-0.50.5-0.50.6-0.50.5-0.7-0.71.0
Bone: trabecular spacing0.10.20.70.4-0.5-0.5-0.6-0.20.4-0.6-0.20.3-0.20.20.4-0.30.3-0.50.1-0.10.60.6-0.8
Bone: trabecular thickness0.20.31.0-0.40.60.70.70.3-0.50.90.2-0.30.2-0.2-0.30.3-0.30.5-0.20.2-0.5-0.51.0
Bone: trabecular tissue density0.10.10.4-0.0-0.1-0.1-0.20.4-0.1-0.40.5-0.40.5-0.4-0.20.4-0.40.1-0.40.40.40.4-0.6
Water consumed over 24 hours0.70.91.8-0.90.60.50.91.0-0.70.41.0-1.41.0-1.0-1.01.2-1.21.0-1.21.2-0.7-0.70.8
Number of responses in last shaping day2.42.53.01.7-1.5-1.5-1.7-1.51.5-1.6-1.51.6-1.61.51.6-1.61.6-1.61.5-1.51.61.6-1.4