Hub : Genes

Tmem201

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Tmem201 0.04 0.03 2.0e-05 0.02 0.03 0.01 0.02 1.6e-04 8.8e-05 4.2e-03 2.5e-04
2 pVTA gene expression Tmem201 0.05 0.04 1.3e-03 0.03 0.04 0.02 0.03 1.2e-03 4.6e-04 4.4e-03 1.7e-03
3 IC gene expression Tmem201 0.14 0.08 5.7e-06 0.12 0.12 0.09 0.1 9.0e-06 7.4e-06 1.6e-04 4.7e-05
4 BLA gene expression Tmem201 0.08 0.05 2.7e-05 0.04 0.07 0.05 0.06 3.4e-03 1.5e-04 9.7e-04 7.0e-04
5 PL gene expression Tmem201 0.09 0.04 5.6e-16 0.15 0.14 0.15 0.15 2.4e-16 1.9e-15 3.7e-16 4.2e-16
6 Brain mRNA stability Tmem201 0.04 0.03 3.4e-05 0.04 0.04 0.04 0.04 1.1e-04 1.1e-04 1.9e-04 4.7e-05
7 NAcc gene expression Tmem201 0.09 0.05 6.9e-10 0.06 0.07 0.05 0.06 8.7e-09 1.9e-10 1.3e-08 8.8e-09
8 BLA mRNA stability Tmem201 0.05 0.03 5.4e-03 0 0.02 -0 0 2.3e-01 2.3e-02 4.2e-01 2.7e-01
9 Adipose mRNA stability Tmem201 0.02 0.01 3.4e-03 0.02 0.01 0 0.01 4.1e-03 2.8e-02 2.4e-01 3.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.10.30.4-0.3-0.3-0.40.30.3-0.20.4-0.6
Area under the delay curve0.10.10.4-0.4-0.1-0.20.2-0.40.10.5-0.40.7
BMI with tail0.20.61.70.6-0.5-0.7-0.60.60.9-0.30.6-1.3
BMI without tail0.10.31.90.00.1-0.1-0.20.30.60.10.4-1.4
Body weight0.10.20.6-0.40.30.30.6-0.5-0.70.4-0.70.3
Weight adjusted by age0.30.81.7-1.00.80.90.9-0.8-1.30.7-0.70.9
Bone surface0.10.20.3-0.50.50.60.5-0.3-0.50.3-0.2-0.1
Bone volume0.00.10.2-0.40.40.40.3-0.2-0.40.1-0.1-0.0
Breakpoint value in progressive ratio session0.40.71.10.8-0.8-0.9-0.91.10.9-0.60.9-0.8
Number of licking bursts0.61.82.51.0-1.4-1.3-1.31.31.6-1.31.4-1.5
Context. condit. distance diff. score5.46.68.52.8-2.7-2.9-2.62.62.6-2.02.2-2.5
Locomotion velocity, session 10.50.61.00.8-1.0-1.0-0.70.70.8-0.40.4-0.8
Locomotion distance, session 10.81.01.51.1-1.2-1.2-0.91.00.8-0.80.6-1.1
Locomotion velocity, session 21.51.82.21.3-1.5-1.4-1.31.41.3-1.31.2-1.2
Locomotion distance, session 20.60.91.61.2-1.3-1.1-0.81.10.4-1.00.5-0.7
Locomotion velocity, session 32.02.33.21.8-1.6-1.6-1.61.71.3-1.41.4-1.3
Locomotion distance, session 33.33.84.82.1-2.2-2.1-2.02.21.4-2.11.9-1.5
Stereotopy head waving bouts, day 30.10.10.20.10.40.30.2-0.2-0.20.3-0.30.3
Stereotopy head waving duration, day 30.70.91.6-0.91.31.20.9-0.9-0.70.9-0.80.8
Locomotion velocity, session 70.70.71.81.4-1.1-1.1-0.81.00.4-0.60.3-0.5
Locomotion distance, session 70.50.71.61.3-1.2-1.1-0.70.90.2-0.60.2-0.4
Stereotopy head waving bouts, day 71.11.32.01.2-0.9-1.1-1.31.21.4-0.71.2-1.2
Stereotopy head waving duration, day 70.20.20.60.20.1-0.2-0.50.40.8-0.00.7-0.6
Locomotion velocity, session 84.55.46.42.3-2.5-2.5-2.42.52.2-2.32.2-2.0
Locomotion distance, session 86.69.611.63.3-3.4-3.4-3.13.32.9-2.82.7-3.0
Degree of sensitization distance0.91.01.5-0.81.01.01.0-1.1-0.71.2-1.20.8
Degree of sensitization stereotypy0.30.40.70.7-0.4-0.6-0.70.60.8-0.20.6-0.7
Conditioned locomotion3.54.19.41.4-2.5-2.0-2.02.11.4-3.12.2-0.1
Cocaine response after cond. corrected1.42.22.6-1.41.61.61.5-1.6-1.31.5-1.51.1
Cocaine response after cond. not corrected1.21.72.7-0.91.31.31.4-1.4-1.21.4-1.71.0
Cocaine response before conditioning0.20.30.90.9-0.8-0.6-0.40.50.2-0.5-0.1-0.3
Saline control response0.10.10.2-0.40.30.30.4-0.2-0.40.3-0.30.1
Bone: connectivity density0.10.20.80.3-0.1-0.2-0.30.40.4-0.10.5-0.9
Bone: cortical apparent density1.52.33.2-1.61.51.61.6-1.4-1.81.3-1.41.5
Bone: cortical area1.22.03.2-1.81.51.51.4-1.4-1.41.3-1.01.2
Bone: cortical porosity0.30.40.80.8-0.9-0.9-0.60.40.5-0.40.10.2
Bone: cortical porosity0.30.30.70.8-0.8-0.8-0.60.40.5-0.30.10.1
Bone: cortical thickness0.50.81.1-1.00.80.80.9-0.9-0.90.9-0.80.9
Bone: cortical thickness0.10.10.20.3-0.4-0.5-0.10.2-0.30.1-0.10.0
Bone: cortical tissue density1.42.23.1-1.51.51.61.6-1.4-1.81.2-1.41.4
Condit. Reinf. active minus inactive responses0.10.10.40.30.1-0.00.20.1-0.30.6-0.4-0.3
Condit. Reinf. active-inactive response ratio2.72.94.2-1.51.71.61.8-1.5-1.92.1-1.81.4
Condit. Reinf. active responses1.11.42.51.6-1.2-1.4-1.11.30.9-0.50.7-1.4
Condit. Reinf. inactive responses7.29.411.63.4-3.1-3.2-3.13.13.1-2.62.7-3.2
Incentive salience index mean1.01.32.1-0.81.21.11.2-0.9-1.41.4-1.30.7
Condit. Reinf. lever presses1.52.22.8-1.51.71.71.6-1.3-1.61.5-1.41.1
Condit. Reinf. active minus inactive responses1.11.72.91.7-1.3-1.3-1.31.31.3-1.00.9-1.3
Condit. Reinf. active-inactive response ratio0.20.31.11.0-0.5-0.6-0.50.50.6-0.20.1-0.6
Condit. Reinf. active responses1.62.32.81.7-1.6-1.5-1.61.71.4-1.71.4-1.2
Condit. Reinf. inactive responses0.10.10.40.0-0.3-0.2-0.30.3-0.1-0.60.40.2
Condit. Reinf. lever presses0.91.31.91.3-1.4-1.3-1.11.30.7-1.30.9-0.8
Condit. Reinf. lever reinforcers received1.72.32.91.7-1.6-1.6-1.61.61.3-1.71.4-1.2
Conditioned reinforcement - actives0.41.72.51.5-1.6-1.6-1.31.21.3-1.10.8-1.3
Conditioned reinforcement - inactives0.20.41.1-0.60.50.60.6-0.5-0.50.5-0.81.0
Conditioned locomotion0.91.32.31.5-1.2-1.4-1.10.91.3-0.60.6-1.1
Patch foraging indifference point 0 sec0.92.43.4-1.41.41.41.7-1.7-1.51.7-1.91.3
Patch foraging indifference point AUC0.00.10.30.30.10.10.2-0.2-0.40.3-0.60.0
Delay disc. indifference point, 0s delay0.20.20.50.6-0.6-0.7-0.2-0.00.10.3-0.40.3
Delay disc. indifference point, 16s delay0.00.10.3-0.4-0.2-0.3-0.1-0.00.50.10.20.1
Delay disc. indifference point, 2s delay0.00.00.1-0.2-0.2-0.2-0.0-0.10.1-0.0-0.00.4
Delay disc. indifference point, 24s delay0.91.43.0-1.70.81.01.1-1.1-1.20.5-0.81.7
Delay disc. indifference point, 4s delay0.50.51.9-0.50.20.20.5-0.6-0.50.7-0.81.4
Delay disc. indifference point, 8s delay0.40.61.5-0.70.50.30.7-1.0-0.21.2-0.90.8
Indifference point function ln k0.10.40.9-1.00.60.70.5-0.7-0.40.3-0.20.7
Indifference point function log k0.10.40.9-1.00.60.70.5-0.7-0.40.3-0.20.7
Patch foraging total patch changes 0 sec0.72.23.0-1.31.41.41.6-1.7-1.41.6-1.71.1
Patch foraging total patch changes 12 sec0.81.01.7-0.71.01.01.1-1.0-1.01.2-1.30.6
Patch foraging total patch changes 18 sec0.20.40.8-0.50.70.60.8-0.8-0.40.8-0.9-0.0
Patch foraging total patch changes 24 sec0.00.00.20.1-0.00.10.2-0.1-0.30.1-0.5-0.0
Patch foraging total patch changes 6 sec1.62.84.2-1.21.61.61.8-1.7-1.91.7-2.11.3
Patch foraging time to switch 0 sec0.00.10.3-0.10.10.20.20.0-0.50.0-0.20.3
Patch foraging water rate 0 sec0.00.10.30.2-0.2-0.2-0.3-0.00.6-0.00.2-0.6
Patch foraging water rate 12 sec0.00.10.60.20.10.0-0.00.10.20.2-0.0-0.8
Patch foraging water rate 18 sec0.10.10.60.10.50.30.1-0.10.10.5-0.1-0.8
Patch foraging water rate 24 sec0.10.10.40.00.40.30.3-0.4-0.20.6-0.3-0.2
Patch foraging water rate 6 sec0.10.20.70.5-0.3-0.4-0.40.10.70.00.3-0.8
Seeking ratio, delayed vs. immediate footshock0.00.00.20.00.0-0.0-0.10.20.30.00.1-0.4
Distance traveled before self-admin1.73.67.42.1-1.9-1.9-1.71.81.5-1.71.5-2.7
Distance traveled after self-admin0.30.61.41.2-0.9-0.9-0.60.60.5-0.40.1-1.1
Extensor digitorum longus weight0.83.15.22.3-2.0-1.9-1.71.91.4-1.51.1-1.6
Bone: elastic displacement4.45.67.52.1-2.4-2.3-2.52.32.5-2.72.5-1.9
Bone: elastic work2.93.84.72.2-2.1-2.1-2.11.91.9-1.91.7-1.4
Bone: endosteal estimation0.71.72.6-1.51.61.61.4-1.3-1.21.2-1.00.8
Bone: endosteal perimeter0.51.11.6-1.21.31.21.1-1.1-0.91.1-0.90.6
Epididymis fat weight1.05.36.4-2.02.12.12.4-2.4-2.32.3-2.52.5
Delta time in closed arm before/after self-admin0.00.00.2-0.40.10.10.10.1-0.1-0.10.20.1
Delta time in open arm before/after self-admin0.00.10.30.6-0.1-0.2-0.20.00.30.0-0.20.1
Diff in mean of infusions in LGA sessions0.10.20.8-0.4-0.10.1-0.30.40.2-0.90.70.3
Delay discount exponential model param0.20.20.70.6-0.00.0-0.30.5-0.0-0.60.4-0.8
Extinction: sum of active levers before priming0.60.91.3-0.91.11.10.9-1.1-0.61.0-1.00.8
Active lever presses in extinction session 60.00.00.10.3-0.1-0.2-0.10.20.1-0.00.0-0.3
Bone: final force1.11.71.9-1.41.31.31.3-1.3-1.31.4-1.21.3
Bone: final moment0.61.01.2-1.01.00.91.0-1.0-1.01.1-1.01.1
Food consumed during 24 hour testing period0.10.10.60.70.10.10.1-0.20.10.2-0.80.2
Glucose0.10.21.00.10.2-0.20.0-0.20.51.0-0.3-0.5
Heart weight12.119.627.34.5-3.9-4.1-4.64.25.2-4.04.3-4.7
Delay discount hyperbolic model param0.10.20.80.50.10.1-0.20.4-0.1-0.40.4-0.9
Intermittent access intake day 1-15 change0.00.20.40.5-0.4-0.6-0.40.30.6-0.00.2-0.6
Intermittent access intake escalation0.00.20.50.5-0.4-0.4-0.40.30.5-0.10.3-0.7
Intermittent access intake escalation 21.01.72.51.6-1.4-1.5-1.41.31.4-0.81.0-1.3
Intermitt. access day 1 inactive lever presses0.00.10.40.0-0.10.00.3-0.4-0.40.2-0.60.6
Intermitt. access day 15 inactive lever presses0.20.91.91.4-1.2-1.2-0.80.90.5-0.60.4-0.8
Intermitt. access escalation Index0.41.31.81.0-1.0-0.9-1.21.11.1-1.31.3-1.3
Intermittent access day 1 total infusions0.30.92.3-0.60.70.91.1-0.8-1.50.6-1.20.9
Intermittent access day 15 total infusions0.20.61.5-0.10.50.60.8-0.6-1.00.8-1.20.3
Intermittent access terminal intake (last 3 days)0.61.12.6-0.50.70.91.2-0.9-1.60.9-1.50.9
Intermittent access total infusions1.41.73.2-0.80.91.11.4-1.2-1.81.1-1.81.1
Intermittent access day 1 locomotion0.91.62.1-1.31.41.41.4-1.3-1.31.3-1.20.6
Intermittent access day 15 total locomotion0.10.30.6-0.20.60.50.5-0.5-0.50.7-0.60.1
Intermittent access total locomotion0.40.50.7-0.70.70.70.8-0.9-0.70.8-0.80.2
Intermittent access standard deviation0.00.20.60.8-0.8-0.7-0.20.40.2-0.2-0.3-0.4
Left kidney weight0.10.51.70.7-0.5-0.6-0.60.50.7-0.40.6-1.3
Right kidney weight0.00.10.50.1-0.1-0.3-0.30.20.5-0.10.4-0.7
Cocaine induced anxiety0.20.50.70.5-0.8-0.9-0.70.80.7-0.70.8-0.3
Post-drug Anxiety0.70.81.00.7-0.9-1.0-0.91.00.8-0.81.0-0.8
Baseline Anxiety0.00.00.2-0.10.10.20.2-0.1-0.4-0.0-0.1-0.1
Tail length0.42.23.2-1.71.31.51.6-1.4-1.81.2-1.31.6
Length with tail0.62.64.7-1.51.11.41.6-1.6-2.11.0-1.62.2
Length without tail0.10.31.10.3-0.9-0.5-0.40.3-0.0-1.10.20.6
Times rat made contact with spout0.10.20.60.8-0.5-0.3-0.30.40.1-0.4-0.1-0.3
Lifetime Intake0.91.12.5-0.60.70.81.2-1.0-1.51.0-1.60.7
Liver weight, left3.96.79.3-2.12.32.32.7-2.7-2.62.8-3.02.6
Liver weight, right3.25.69.6-1.52.01.82.4-2.5-2.53.0-3.12.0
Locomotor activity2.03.16.01.5-1.5-1.7-1.91.62.4-1.41.8-1.7
Locomotor testing distance1.23.14.51.8-1.5-1.7-1.81.72.1-1.31.7-2.0
Locomotor testing rearing0.00.20.80.7-0.2-0.2-0.20.30.30.00.0-0.9
Locomotion in novel chamber4.35.88.02.8-2.6-2.5-2.42.81.9-2.32.0-2.2
Locomotion in novel chamber post-restriction0.61.72.90.8-1.1-1.0-1.41.41.5-1.61.7-0.9
Fecal boli incidents, locomotor time 11.13.07.0-0.81.11.01.7-1.9-1.52.4-2.61.5
Change in fecal boli incidents, locomotor task0.60.72.20.4-0.6-0.4-0.90.70.7-1.51.2-0.0
Time >=10cm from walls, locomotor time 10.10.10.1-0.30.30.30.0-0.40.3-0.00.2-0.3
Bouts of movement, locomotor time 10.70.91.5-0.60.70.61.0-0.7-1.21.1-1.20.9
Total resting periods, locomotor time 10.91.02.1-0.80.70.81.1-0.8-1.41.0-1.21.0
Rest time, locomotor task time 10.71.21.51.2-1.1-1.1-1.11.20.8-1.11.0-0.9
Distance moved, locomotor task time 10.00.10.3-0.2-0.2-0.1-0.20.2-0.1-0.60.40.2
Vertical activity count, locomotor time 10.10.41.1-0.1-0.00.0-0.50.50.7-0.81.1-1.0
Time >=10cm from walls, locomotor time 20.41.21.7-1.11.21.31.2-1.1-1.01.0-1.00.9
Bouts of movement, locomotor time 20.20.50.9-0.80.70.70.7-0.7-0.80.7-0.61.0
Total resting periods, locomotor time 20.00.20.4-0.50.40.40.3-0.2-0.50.2-0.10.7
Rest time, locomotor task time 22.03.43.91.9-1.7-1.7-1.92.01.8-2.01.9-1.9
Distance moved, locomotor task time 20.20.30.9-0.20.20.30.4-0.3-0.90.2-0.50.9
Vertical activity count, locomotor time 20.00.00.10.1-0.0-0.0-0.20.20.1-0.20.3-0.1
Light reinforcement 10.00.20.70.50.2-0.1-0.0-0.10.30.9-0.3-0.4
Light reinforcement 20.00.00.1-0.10.10.10.0-0.0-0.1-0.10.10.3
Bone: marrow area0.61.42.2-1.41.51.51.2-1.2-1.11.1-0.90.7
Bone: maximum diameter0.91.73.0-1.71.51.41.4-1.3-1.21.3-0.90.8
Bone: maximum force0.81.71.8-1.31.31.31.3-1.3-1.31.3-1.21.1
Bone: maximum moment0.40.80.9-0.80.90.90.9-0.9-0.90.8-0.80.8
Mean time between licks in bursts0.31.93.2-1.71.81.61.4-1.4-1.11.5-0.90.9
Mean num. licks in bursts0.71.82.8-0.81.31.31.4-1.2-1.71.3-1.61.3
Cd content in liver0.10.10.5-0.10.20.20.1-0.2-0.20.1-0.10.7
Co content in liver0.70.91.41.2-1.1-1.0-0.90.91.0-0.70.5-0.9
Cu content in liver0.70.91.30.5-1.0-0.9-0.90.81.0-1.11.1-0.8
Fe content in liver0.20.20.50.1-0.4-0.3-0.30.60.1-0.60.6-0.7
K content in liver0.50.51.20.7-0.7-0.5-0.70.60.6-1.10.7-0.5
Mg content in liver0.30.30.6-0.80.70.70.5-0.7-0.30.3-0.20.3
Mn content in liver0.20.20.4-0.40.60.60.4-0.4-0.30.3-0.2-0.3
Na content in liver1.01.22.60.4-1.0-0.8-1.11.01.0-1.61.5-0.9
Rb content in liver0.10.10.5-0.1-0.10.1-0.20.30.2-0.70.5-0.3
Se content in liver1.41.62.4-1.51.51.51.3-1.3-1.41.1-0.91.0
Sr content in liver0.70.60.9-0.70.90.90.7-0.8-0.80.6-0.60.9
Zn content in liver1.11.32.3-0.80.80.71.1-1.5-0.71.5-1.51.1
Bone: minimum diameter2.34.45.4-2.32.32.32.2-2.2-2.11.9-1.81.6
Time in familiar zone, hab. session 10.30.40.50.7-0.7-0.7-0.70.60.6-0.60.5-0.3
Time in novel zone, hab. session 10.60.71.6-1.30.90.90.9-0.7-0.70.7-0.50.5
Total zone transitions, hab. session 10.30.51.50.6-0.8-0.5-0.60.80.0-1.20.6-0.1
Total locomotion distance, hab. session 10.50.71.61.3-1.2-1.0-0.80.80.3-1.10.30.1
Locomotion velocity, hab. session 10.71.02.31.5-1.4-1.2-1.00.90.5-1.20.4-0.1
Time in familiar zone, hab. session 20.50.61.50.2-0.2-0.2-0.60.51.0-0.71.0-1.2
Time in novel zone, hab. session 20.10.10.30.2-0.1-0.20.2-0.1-0.20.6-0.60.3
Total zone transitions, hab. session 23.64.66.41.8-2.0-2.0-2.12.22.0-2.32.3-2.5
Total locomotion distance, hab. session 23.24.16.22.5-2.2-2.2-2.01.91.9-1.81.5-2.1
Locomotion velocity, hab. session 22.23.04.92.2-1.9-1.9-1.71.61.5-1.51.2-1.8
Novel to familiar place preference ratio0.20.30.6-0.10.40.30.5-0.4-0.60.7-0.80.3
Novelty place preference0.10.20.5-0.10.30.20.4-0.3-0.50.7-0.60.1
Time in novel zone, NPP test0.20.20.5-0.20.40.30.5-0.4-0.50.7-0.70.2
Total zone transitions, NPP test2.84.26.21.9-2.5-2.2-2.12.01.7-2.51.9-1.3
Total locomotion distance, NPP test3.24.47.82.8-2.7-2.5-2.12.01.6-2.31.3-1.0
Locomotion velocity, NPP test3.44.88.32.9-2.8-2.6-2.22.11.7-2.31.4-1.1
Intraocular pressure0.10.20.90.40.1-0.10.2-0.0-0.00.7-0.5-0.9
Delta distance traveled before/after self-admin0.50.51.9-0.30.20.40.6-0.6-0.80.4-0.91.4
Delta ambulatory time before/after self-admin0.61.02.8-0.60.70.80.9-0.9-1.10.7-1.21.7
Parametrial fat weight0.82.05.5-0.01.00.81.4-1.4-1.32.0-2.31.0
Pavlov. Cond. lever latency0.60.81.00.9-0.9-0.9-0.90.90.8-0.80.8-1.0
Pavlov. Cond. magazine entry latency2.22.94.7-1.92.22.01.7-1.8-1.31.9-1.30.7
Pavlov. Cond. change in total contacts0.30.30.5-0.60.70.60.5-0.5-0.40.6-0.40.5
Pavlov. Cond. index score2.33.04.1-2.02.01.91.8-1.7-1.51.7-1.41.2
Pavlov. Cond. latency score1.51.92.7-1.71.61.61.4-1.4-1.21.4-1.01.1
Pavlov. Cond. lever contacts0.91.11.3-1.01.11.11.1-1.0-1.11.1-1.11.0
Pavlov. Cond. magazine entry number1.31.72.71.5-1.6-1.5-1.41.31.2-1.31.0-0.6
Pavlov. Cond. intertrial magazine entries2.53.06.02.5-2.2-2.2-1.71.71.4-1.20.8-1.0
Pavlov. Cond. lever-magazine prob. diff.2.83.54.7-2.22.22.11.9-1.9-1.71.9-1.51.4
Pavlov. Cond. response bias1.31.72.5-1.31.61.51.4-1.3-1.21.3-1.10.8
Pavlov. Cond. lever latency2.33.24.5-2.11.91.81.8-1.9-1.51.8-1.51.7
Pavlov. Cond. magazine entry latency0.00.10.20.10.20.10.2-0.20.00.4-0.4-0.4
Pavlov. Cond. change in total contacts0.20.40.90.9-0.6-0.6-0.60.70.5-0.60.5-1.0
Pavlov. Cond. index score0.20.40.80.9-0.6-0.6-0.60.60.5-0.50.3-0.8
Pavlov. Cond. latency score0.20.40.80.9-0.6-0.6-0.60.70.4-0.50.4-0.8
Pavlov. Cond. lever contacts2.03.04.22.0-1.9-1.8-1.71.81.4-1.81.4-1.6
Pavlov. Cond. magazine entry number0.00.00.2-0.2-0.00.10.1-0.1-0.3-0.1-0.00.5
Pavlov. Cond. intertrial magazine entries0.51.11.7-0.91.21.01.1-1.1-1.11.3-1.10.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.9-0.5-0.5-0.50.60.4-0.40.3-0.9
Pavlov. Cond. response bias1.52.13.31.8-1.6-1.5-1.41.41.3-1.31.0-1.4
Time in closed arm before self-admin0.10.10.40.10.20.00.2-0.3-0.10.6-0.4-0.6
Time in closed arm after self-admin0.40.51.4-1.20.80.70.8-0.6-0.60.8-0.30.3
Time in open arm before self-admin0.20.30.50.2-0.5-0.4-0.60.40.6-0.70.60.5
Time in open arm after self-admin0.80.91.81.3-0.9-0.9-1.10.91.1-1.00.7-0.3
Bone: periosteal estimation1.43.34.7-2.22.02.11.9-1.9-1.71.6-1.41.4
Bone: periosteal perimeter0.71.52.3-1.51.41.41.2-1.3-0.91.3-0.90.7
Bone: post-yield work1.01.82.3-1.11.21.31.4-1.4-1.41.4-1.51.2
Progressive ratio test 1 active lever presses0.00.10.4-0.1-0.10.20.3-0.1-0.6-0.2-0.30.1
Progressive ratio test 1 breakpoint0.10.10.4-0.1-0.10.20.3-0.2-0.6-0.2-0.40.1
Progressive ratio test 1 inactive lever presses0.10.20.9-0.0-0.10.20.4-0.1-0.9-0.2-0.60.9
Progressive ratio test 2 active lever presses0.60.82.2-0.50.50.71.0-0.8-1.50.6-1.20.8
Progressive ratio test 2 breakpoint0.60.82.3-0.60.50.71.0-0.8-1.50.5-1.20.8
Progressive ratio test 2 inactive lever presses0.20.51.5-0.20.20.40.7-0.4-1.20.2-1.01.1
Incentive Sensitization - Responses0.30.82.1-0.80.40.70.9-0.7-1.40.2-0.91.3
Incentive Sensitization - Breakpoint0.40.82.2-0.80.50.70.9-0.8-1.50.3-0.91.3
Sum of active levers in priming session hrs 5-60.10.10.4-0.20.40.20.20.10.00.6-0.1-0.1
Progressive ratio0.00.10.4-0.2-0.2-0.1-0.20.40.2-0.60.4-0.2
Food seeking constrained by brief footshock3.44.25.92.4-2.1-2.2-2.02.11.8-1.61.6-2.4
Seeking ratio, punishment vs. effort0.40.81.71.3-1.0-1.1-0.90.80.6-0.60.6-0.9
Retroperitoneal fat weight0.00.10.10.20.30.20.2-0.1-0.20.2-0.3-0.3
Reaction time number correct0.00.10.3-0.00.40.30.0-0.30.50.4-0.1-0.3
Reaction time mean minus median0.52.93.5-1.71.81.71.8-1.9-1.51.9-1.71.3
Reaction time mean minus median AUC0.00.30.4-0.50.60.60.6-0.6-0.30.6-0.50.1
Reaction time num false alarms0.20.30.8-0.50.90.80.4-0.5-0.20.6-0.2-0.6
Reaction time num false alarms AUC0.10.21.00.00.40.2-0.20.10.40.10.5-1.0
Reaction time trials correct on left0.00.10.3-0.00.40.30.0-0.30.50.4-0.1-0.3
Reaction time trials on left0.00.10.2-0.10.50.30.1-0.30.40.4-0.2-0.2
Reaction time mean1.02.12.9-1.71.61.51.5-1.6-1.01.6-1.31.2
Reaction time mean AUC0.92.23.0-1.71.71.61.5-1.6-1.11.6-1.31.2
Median of all reaction times0.91.52.1-1.41.41.21.2-1.3-0.71.4-1.11.0
Reaction time omissions0.40.60.9-0.90.90.90.8-0.7-0.70.6-0.70.7
Reaction time false alarm rate0.00.10.3-0.00.20.1-0.10.1-0.0-0.10.3-0.6
Reaction time premature initiation rate1.62.53.7-1.31.81.61.7-1.7-1.41.9-1.81.0
Reaction time premature initiations0.82.44.2-1.31.81.61.6-1.7-1.02.0-1.70.7
Std. dev. reaction times1.03.44.1-2.02.01.91.9-1.9-1.61.9-1.71.5
Reaction time trials completed0.00.10.2-0.10.50.30.1-0.30.40.4-0.2-0.2
Reaction time trials AUC0.00.10.3-0.10.50.40.1-0.40.40.6-0.3-0.2
Run reversals in cocaine runway, females0.91.02.00.2-1.0-1.0-1.00.91.2-1.11.4-1.0
Run reversals in cocaine runway, males1.41.62.01.4-1.2-1.1-1.21.21.1-1.41.1-1.4
Latency to leave start box in cocaine runway0.00.00.1-0.20.10.10.1-0.00.10.1-0.10.1
Latency to leave start box in cocaine runway, F0.10.10.3-0.0-0.1-0.10.2-0.2-0.30.2-0.50.2
Latency to leave start box in cocaine runway, M0.20.20.6-0.50.20.1-0.30.30.7-0.40.8-0.1
Std. dev. time between licks in bursts0.30.51.40.1-0.3-0.4-0.70.51.2-0.61.0-0.8
Total sessions with >9 infusions0.10.10.1-0.20.10.20.3-0.2-0.30.0-0.4-0.3
Short access day 1 total inactive lever presses0.10.20.40.5-0.6-0.6-0.20.50.0-0.2-0.1-0.4
Short access day 10 total inactive lever presses0.00.00.20.1-0.2-0.2-0.1-0.10.10.0-0.00.5
Short access day 1 total infusions0.10.10.5-0.30.10.30.3-0.0-0.4-0.0-0.3-0.7
Short access day 10 total infusions0.40.61.1-0.60.70.80.9-0.8-1.00.6-1.10.7
Short access total infusions0.20.20.8-0.20.20.40.6-0.4-0.70.3-0.90.1
Short access day 1 locomotion0.10.10.2-0.40.20.50.4-0.3-0.5-0.2-0.30.2
Short access day 10 total locomotion0.10.61.90.2-0.4-0.4-0.60.51.0-0.61.0-1.4
Short access total locomotion0.10.11.00.10.0-0.0-0.10.10.5-0.00.2-1.0
One hour access (0.3 mA shock)0.40.40.9-0.30.40.50.7-0.7-0.90.6-0.90.6
Compulsive drug intake1.01.52.81.2-1.0-1.1-1.21.11.4-1.11.2-1.7
One hour access (shock baseline)0.51.22.6-0.50.60.71.1-1.1-1.41.0-1.61.2
Social response proportion0.20.20.80.1-0.7-0.3-0.10.4-0.5-0.90.20.1
Social responses0.30.40.80.8-0.9-0.7-0.60.70.2-0.90.4-0.2
Social time0.40.71.11.1-0.9-0.9-0.81.01.0-0.60.5-0.7
Soleus weight0.51.63.51.9-1.3-1.4-1.21.21.1-0.70.5-1.4
Bone: stiffness2.34.24.7-2.02.12.22.1-2.1-2.21.9-1.91.9
Tibialis anterior weight0.00.10.40.5-0.1-0.10.2-0.0-0.30.3-0.7-0.0
Time to tail flick, vehicle, before self-admin1.31.63.40.8-0.9-1.0-1.21.11.5-1.01.4-1.8
Time to tail flick, vehicle, after self-admin0.20.40.80.6-0.7-0.7-0.60.40.8-0.50.5-0.9
Time to tail flick, test, before self-admin1.21.32.50.5-1.2-1.2-1.31.11.2-1.31.6-0.6
Time to tail flick, test, after self-admin3.53.64.81.6-1.8-1.9-2.11.82.2-1.82.1-1.8
Delta time to tail flick, vehicle, before/after SA0.60.71.5-0.30.50.50.8-0.9-0.80.9-1.21.0
Delta time to tail flick, test, before/after SA0.10.10.40.6-0.3-0.4-0.40.20.5-0.10.2-0.5
Tibia length1.33.55.6-2.01.82.01.9-1.7-2.41.4-1.51.9
Ambulatory time before self-admin1.03.25.51.9-1.9-1.8-1.71.81.3-1.71.5-2.3
Ambulatory time after self-admin0.20.41.11.0-0.6-0.6-0.30.40.3-0.2-0.1-1.1
Bone: tissue strength0.10.10.4-0.00.00.20.0-0.1-0.1-0.2-0.10.6
Total heroin consumption0.30.30.80.5-0.7-0.6-0.50.90.2-0.70.4-0.2
Bone: trabecular number0.20.30.70.3-0.3-0.4-0.50.50.6-0.40.7-0.9
Bone: trabecular spacing0.10.20.3-0.50.40.30.4-0.5-0.10.6-0.40.5
Bone: trabecular thickness0.10.10.40.6-0.4-0.5-0.40.40.3-0.20.2-0.3
Bone: trabecular tissue density0.40.71.1-0.90.70.60.8-1.0-0.71.0-0.80.9
Water consumed over 24 hours0.10.31.00.8-0.2-0.3-0.30.20.6-0.1-0.1-1.0
Number of responses in last shaping day0.20.30.5-0.60.50.50.5-0.6-0.30.4-0.40.7