Hub : Genes

Tmem198b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tmem198b 0.03 0.03 8.8e-03 0.02 0.02 0.01 0.02 2.1e-03 5.8e-03 4.0e-02 3.8e-03
2 Brain mRNA stability Tmem198b 0.2 0.12 7.2e-11 0.08 0.09 0.1 0.1 9.6e-08 6.1e-09 6.7e-10 1.7e-09
3 OFC gene expression Tmem198b 0.24 0.16 2.4e-03 0.05 0.02 0.04 0.04 2.3e-02 9.2e-02 3.9e-02 4.8e-02
4 NAcc gene expression Tmem198b 0.04 0.03 1.9e-05 0.03 0.03 0.03 0.03 1.9e-05 7.9e-06 2.1e-05 7.9e-06
5 Brain gene expression Tmem198b 0.11 0.07 4.9e-07 0.04 0.04 0.04 0.05 1.0e-04 9.9e-05 6.3e-05 4.0e-05
6 pVTA mRNA stability Tmem198b 0.06 0.04 1.3e-03 0.04 0.04 0.04 0.04 4.6e-04 5.8e-04 7.0e-04 7.8e-04
7 NAcc mRNA stability Tmem198b 0.03 0.02 1.8e-04 0.02 0.02 0.02 0.02 1.1e-04 1.6e-04 1.4e-04 1.6e-04
8 BLA mRNA stability Tmem198b 0.05 0.04 6.1e-03 0.04 0.02 0.01 0.02 3.7e-03 4.1e-02 8.9e-02 2.5e-02
9 PL mRNA stability Tmem198b 0.06 0.04 1.3e-05 0.03 0.03 0.04 0.04 2.9e-04 3.8e-04 7.5e-05 2.6e-05
10 OFC mRNA stability Tmem198b 0.16 0.13 9.9e-03 0.09 0.07 -0.01 0.08 4.5e-03 7.6e-03 5.7e-01 5.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.61.06.11.1-0.40.9-0.10.20.80.50.50.52.5
Area under the delay curve0.20.20.40.5-0.60.60.40.5-0.4-0.3-0.3-0.40.2
BMI with tail8.027.833.25.5-5.75.55.75.8-5.4-5.4-5.4-5.4-1.1
BMI without tail2.37.08.72.8-2.82.62.83.0-2.6-2.8-2.8-2.8-0.7
Body weight1.56.88.62.5-2.62.42.62.9-2.7-2.8-2.9-2.9-1.1
Weight adjusted by age0.00.00.1-0.30.2-0.3-0.2-0.00.1-0.3-0.0-0.1-0.3
Bone surface1.52.813.90.70.30.4-0.9-0.72.11.61.61.63.7
Bone volume1.42.514.11.1-0.00.8-0.5-0.41.71.41.41.33.7
Breakpoint value in progressive ratio session1.01.21.8-1.31.3-1.3-1.2-1.30.90.91.01.00.1
Number of licking bursts2.64.25.21.9-2.11.82.12.2-2.3-2.0-2.3-2.3-1.4
Context. condit. distance diff. score0.20.30.40.4-0.60.60.60.5-0.6-0.5-0.5-0.5-0.2
Locomotion velocity, session 10.40.52.11.0-0.61.00.30.20.00.30.10.21.4
Locomotion distance, session 10.70.83.30.20.30.2-0.5-0.60.91.11.01.11.8
Locomotion velocity, session 22.22.64.4-0.71.2-0.8-1.5-1.61.91.91.91.92.1
Locomotion distance, session 22.63.65.3-1.01.6-1.1-1.9-1.82.22.32.22.22.1
Locomotion velocity, session 34.24.85.9-2.42.4-2.3-2.4-2.42.22.22.22.30.2
Locomotion distance, session 30.00.10.1-0.30.2-0.3-0.2-0.30.10.20.20.2-0.2
Stereotopy head waving bouts, day 35.96.98.3-2.52.8-2.7-2.9-2.82.92.72.72.71.0
Stereotopy head waving duration, day 34.85.76.8-2.42.6-2.5-2.6-2.52.62.42.52.50.8
Locomotion velocity, session 70.20.20.3-0.20.3-0.0-0.3-0.50.40.50.50.60.6
Locomotion distance, session 70.20.20.9-0.0-0.20.10.40.3-0.6-0.5-0.4-0.5-0.9
Stereotopy head waving bouts, day 71.01.22.1-0.40.8-0.5-1.0-1.01.21.31.31.31.4
Stereotopy head waving duration, day 71.01.23.0-0.30.7-0.3-0.9-1.01.21.31.31.31.7
Locomotion velocity, session 81.41.74.0-0.30.8-0.4-1.2-1.11.51.61.51.52.0
Locomotion distance, session 80.30.40.6-0.40.5-0.3-0.6-0.60.70.70.80.70.7
Degree of sensitization distance0.50.60.80.8-0.80.90.80.8-0.8-0.7-0.7-0.7-0.0
Degree of sensitization stereotypy0.20.20.90.7-0.50.80.30.2-0.1-0.00.00.01.0
Conditioned locomotion1.41.62.90.6-1.00.71.21.2-1.6-1.5-1.4-1.4-1.7
Cocaine response after cond. corrected2.42.93.91.2-1.51.21.71.7-2.0-1.9-1.9-1.9-1.7
Cocaine response after cond. not corrected2.52.94.01.1-1.51.11.71.7-2.0-2.0-2.0-2.0-1.8
Cocaine response before conditioning0.60.70.9-0.80.8-0.9-0.9-0.90.90.80.80.80.6
Saline control response0.91.21.70.8-1.00.71.01.2-1.1-1.3-1.3-1.3-0.9
Bone: connectivity density0.30.53.20.7-0.10.4-0.10.10.70.40.40.41.8
Bone: cortical apparent density0.81.11.61.2-1.21.31.21.1-1.1-1.1-0.9-0.9-0.0
Bone: cortical area0.50.82.61.4-1.01.30.70.6-0.1-0.1-0.1-0.11.6
Bone: cortical porosity0.10.10.60.10.00.1-0.1-0.20.40.20.30.30.8
Bone: cortical porosity0.20.21.40.5-0.20.40.10.00.40.10.20.21.2
Bone: cortical thickness0.91.52.91.7-1.41.71.41.2-0.9-0.9-0.8-0.80.9
Bone: cortical thickness0.80.91.30.8-0.90.91.11.0-1.1-0.9-1.0-1.0-0.7
Bone: cortical tissue density0.60.81.11.0-1.01.11.00.9-0.9-0.9-0.7-0.8-0.0
Condit. Reinf. active minus inactive responses2.22.53.0-1.61.7-1.5-1.7-1.71.61.71.71.70.4
Condit. Reinf. active-inactive response ratio0.40.40.9-1.00.8-0.9-0.7-0.60.50.40.50.4-0.5
Condit. Reinf. active responses3.34.05.4-1.72.0-1.7-2.1-2.22.22.32.22.31.3
Condit. Reinf. inactive responses1.72.13.2-0.81.2-0.8-1.4-1.41.61.81.71.71.6
Incentive salience index mean1.51.92.8-1.01.2-0.9-1.4-1.51.51.71.61.61.1
Condit. Reinf. lever presses0.60.83.50.20.20.3-0.5-0.60.91.21.01.01.9
Condit. Reinf. active minus inactive responses2.32.95.0-2.22.0-2.2-1.8-1.81.41.41.41.4-0.8
Condit. Reinf. active-inactive response ratio0.70.92.6-1.41.0-1.3-0.7-0.70.10.20.30.2-1.6
Condit. Reinf. active responses2.02.73.8-1.81.9-2.0-1.8-1.71.71.61.61.50.0
Condit. Reinf. inactive responses0.60.71.3-0.50.8-0.7-0.9-0.81.21.00.90.90.8
Condit. Reinf. lever presses2.53.45.4-2.22.2-2.3-2.0-1.91.81.61.71.6-0.5
Condit. Reinf. lever reinforcers received1.52.03.3-1.71.7-1.8-1.6-1.41.41.31.31.2-0.3
Conditioned reinforcement - actives0.10.20.5-0.60.6-0.7-0.4-0.40.50.00.50.3-0.1
Conditioned reinforcement - inactives0.20.30.9-0.50.2-0.50.20.2-0.4-0.9-0.3-0.5-0.8
Conditioned locomotion4.15.46.7-2.42.6-2.5-2.3-2.52.61.92.52.50.8
Patch foraging indifference point 0 sec2.54.66.12.5-2.42.42.42.3-1.9-2.2-2.1-2.00.3
Patch foraging indifference point AUC0.50.71.1-1.11.0-1.0-0.9-0.90.80.80.80.7-0.2
Delay disc. indifference point, 0s delay2.02.24.82.2-1.82.21.41.5-0.9-0.8-0.9-0.91.5
Delay disc. indifference point, 16s delay0.10.10.3-0.30.3-0.1-0.3-0.40.30.60.50.50.3
Delay disc. indifference point, 2s delay0.60.61.41.1-1.01.20.70.8-0.6-0.3-0.5-0.50.8
Delay disc. indifference point, 24s delay0.60.60.90.8-0.91.00.80.9-0.8-0.8-0.7-0.8-0.0
Delay disc. indifference point, 4s delay0.30.31.20.10.20.0-0.4-0.30.70.70.60.61.1
Delay disc. indifference point, 8s delay0.40.50.80.4-0.60.40.60.8-0.8-0.8-0.8-0.9-0.8
Indifference point function ln k0.00.00.00.0-0.1-0.00.20.0-0.1-0.0-0.1-0.1-0.1
Indifference point function log k0.00.00.00.0-0.1-0.00.20.0-0.1-0.0-0.1-0.1-0.1
Patch foraging total patch changes 0 sec2.14.05.22.3-2.22.22.22.1-1.8-2.0-2.0-1.90.3
Patch foraging total patch changes 12 sec2.02.63.61.4-1.61.41.61.8-1.6-1.9-1.8-1.9-0.8
Patch foraging total patch changes 18 sec0.10.10.20.3-0.30.40.30.3-0.2-0.5-0.3-0.30.3
Patch foraging total patch changes 24 sec0.40.71.21.0-1.01.10.90.9-0.7-0.8-0.7-0.70.5
Patch foraging total patch changes 6 sec1.31.92.61.6-1.61.61.51.5-1.2-1.3-1.3-1.30.1
Patch foraging time to switch 0 sec0.20.51.31.1-0.91.00.60.7-0.2-0.4-0.3-0.40.8
Patch foraging water rate 0 sec0.40.91.40.4-0.70.40.90.9-1.2-1.1-1.2-1.1-1.2
Patch foraging water rate 12 sec0.51.01.80.4-0.70.51.10.9-1.3-1.1-1.2-1.2-1.2
Patch foraging water rate 18 sec0.71.05.4-0.90.3-0.80.20.2-0.9-0.8-0.9-0.9-2.3
Patch foraging water rate 24 sec2.63.68.10.4-1.20.51.61.7-2.4-2.1-2.3-2.3-2.8
Patch foraging water rate 6 sec0.71.02.6-1.61.2-1.6-0.7-0.80.20.20.20.3-1.5
Seeking ratio, delayed vs. immediate footshock2.02.43.2-1.41.6-1.4-1.6-1.61.81.61.71.71.0
Distance traveled before self-admin1.21.62.0-1.31.4-1.3-1.4-1.41.21.41.21.30.4
Distance traveled after self-admin0.00.00.00.2-0.20.10.10.2-0.1-0.2-0.2-0.2-0.0
Extensor digitorum longus weight5.421.124.94.4-4.84.24.95.0-4.9-4.9-5.0-5.0-2.2
Bone: elastic displacement0.00.00.0-0.00.0-0.00.0-0.10.1-0.10.00.00.1
Bone: elastic work0.71.01.81.3-1.21.31.01.0-0.6-0.8-0.8-0.80.6
Bone: endosteal estimation0.30.61.21.1-0.91.10.80.8-0.4-0.5-0.5-0.50.8
Bone: endosteal perimeter0.61.21.9-0.50.8-0.6-1.0-1.01.41.21.21.31.4
Epididymis fat weight0.10.31.5-0.80.5-0.6-0.2-0.1-0.3-0.2-0.1-0.2-1.2
Delta time in closed arm before/after self-admin1.91.84.70.1-0.60.11.11.1-1.5-1.6-1.6-1.7-2.2
Delta time in open arm before/after self-admin1.61.52.21.3-1.41.51.31.3-1.4-1.2-1.2-1.2-0.2
Diff in mean of infusions in LGA sessions2.02.53.3-1.81.8-1.8-1.7-1.71.51.51.51.50.0
Delay discount exponential model param0.10.10.3-0.40.4-0.5-0.3-0.40.30.20.30.3-0.2
Extinction: sum of active levers before priming1.41.62.9-1.71.5-1.6-1.3-1.40.90.90.91.1-0.8
Active lever presses in extinction session 60.30.30.5-0.30.4-0.3-0.5-0.60.50.50.60.70.5
Bone: final force2.13.46.92.6-2.22.61.91.9-1.2-1.3-1.2-1.21.4
Bone: final moment2.13.46.92.6-2.22.61.91.9-1.2-1.3-1.2-1.21.4
Food consumed during 24 hour testing period0.30.50.70.8-0.70.80.70.8-0.7-0.6-0.7-0.7-0.1
Glucose1.82.93.41.7-1.81.81.81.8-1.9-1.8-1.7-1.8-0.4
Heart weight0.30.40.9-1.00.8-0.9-0.6-0.60.40.20.40.3-0.7
Delay discount hyperbolic model param0.30.40.8-0.80.8-0.9-0.6-0.70.50.30.50.5-0.4
Intermittent access intake day 1-15 change0.61.33.2-1.81.5-1.8-1.1-1.10.70.40.70.6-0.7
Intermittent access intake escalation0.51.12.9-1.71.4-1.7-1.0-0.90.60.30.60.5-0.7
Intermittent access intake escalation 20.91.02.2-1.51.3-1.5-1.1-1.00.70.60.80.7-0.3
Intermitt. access day 1 inactive lever presses0.20.82.4-1.41.0-1.5-0.7-0.60.1-0.00.00.1-1.5
Intermitt. access day 15 inactive lever presses0.40.91.6-1.31.1-1.3-1.0-1.00.60.90.70.7-0.2
Intermitt. access escalation Index0.10.20.80.5-0.30.50.10.10.30.10.20.30.9
Intermittent access day 1 total infusions0.00.10.20.0-0.10.10.20.2-0.2-0.5-0.2-0.3-0.4
Intermittent access day 15 total infusions0.20.20.5-0.70.7-0.7-0.4-0.40.40.10.50.40.0
Intermittent access terminal intake (last 3 days)0.30.40.7-0.60.7-0.6-0.6-0.70.80.50.80.70.6
Intermittent access total infusions0.00.00.1-0.20.2-0.2-0.1-0.10.2-0.20.20.10.1
Intermittent access day 1 locomotion0.10.21.0-0.30.1-0.30.10.1-0.3-0.6-0.3-0.3-1.0
Intermittent access day 15 total locomotion0.61.02.5-1.61.3-1.6-0.9-1.00.70.10.80.7-0.5
Intermittent access total locomotion0.30.40.9-0.90.8-0.9-0.6-0.50.5-0.10.50.4-0.4
Intermittent access standard deviation1.12.33.0-1.61.7-1.6-1.5-1.61.71.31.71.50.6
Left kidney weight0.00.10.20.0-0.20.10.20.3-0.4-0.2-0.3-0.3-0.5
Right kidney weight0.10.30.6-0.70.6-0.7-0.6-0.50.30.40.40.4-0.7
Cocaine induced anxiety1.62.33.3-1.01.3-0.9-1.5-1.51.81.71.71.81.6
Post-drug Anxiety1.51.64.6-0.30.8-0.3-1.0-1.01.51.21.51.52.2
Baseline Anxiety0.00.00.10.1-0.10.10.10.2-0.1-0.1-0.1-0.20.1
Tail length3.011.715.4-3.83.8-3.9-3.8-3.63.53.33.33.3-0.0
Length with tail1.15.08.0-2.82.7-2.8-2.5-2.32.11.91.91.8-0.6
Length without tail0.30.91.30.6-0.80.70.91.0-1.1-1.1-1.1-1.1-0.8
Times rat made contact with spout1.51.72.31.0-1.21.11.31.4-1.5-1.4-1.5-1.5-0.9
Lifetime Intake0.10.10.40.2-0.20.20.30.3-0.1-0.6-0.1-0.20.3
Liver weight, left0.50.81.00.9-0.91.01.00.9-1.0-0.8-0.9-0.8-0.4
Liver weight, right0.00.10.4-0.20.1-0.2-0.20.1-0.1-0.2-0.1-0.2-0.6
Locomotor activity3.04.76.0-1.82.1-1.8-2.3-2.32.42.32.42.51.4
Locomotor testing distance1.52.73.5-1.41.6-1.3-1.7-1.71.91.71.91.81.1
Locomotor testing rearing0.00.00.2-0.10.0-0.2-0.00.1-0.1-0.3-0.2-0.2-0.4
Locomotion in novel chamber0.00.00.0-0.00.0-0.00.10.00.1-0.10.0-0.00.0
Locomotion in novel chamber post-restriction3.25.26.3-2.52.5-2.2-2.5-2.52.22.52.32.30.4
Fecal boli incidents, locomotor time 10.91.42.00.9-1.10.91.21.1-1.4-1.2-1.4-1.3-1.0
Change in fecal boli incidents, locomotor task1.01.02.2-0.40.7-0.4-0.9-0.91.21.21.21.11.5
Time >=10cm from walls, locomotor time 10.50.51.41.0-0.81.00.60.6-0.2-0.3-0.3-0.21.2
Bouts of movement, locomotor time 10.70.71.1-1.01.0-1.1-1.0-0.90.80.80.80.7-0.2
Total resting periods, locomotor time 11.31.41.9-1.31.3-1.4-1.4-1.31.21.21.21.10.0
Rest time, locomotor task time 10.40.50.7-0.50.6-0.5-0.8-0.70.90.80.80.70.7
Distance moved, locomotor task time 10.40.61.51.1-0.81.10.70.6-0.3-0.4-0.2-0.21.2
Vertical activity count, locomotor time 10.30.81.20.8-0.90.91.10.9-1.0-1.1-0.9-0.8-0.3
Time >=10cm from walls, locomotor time 20.71.11.80.8-1.00.81.11.1-1.1-1.3-1.2-1.1-0.8
Bouts of movement, locomotor time 20.30.41.2-0.10.4-0.2-0.6-0.40.80.90.70.71.1
Total resting periods, locomotor time 20.30.51.6-0.00.3-0.1-0.6-0.50.80.90.70.71.3
Rest time, locomotor task time 20.20.20.90.10.10.1-0.3-0.20.50.40.50.51.0
Distance moved, locomotor task time 20.10.10.7-0.30.1-0.20.10.1-0.3-0.5-0.3-0.3-0.9
Vertical activity count, locomotor time 21.11.52.40.7-1.00.71.21.1-1.5-1.6-1.4-1.4-1.4
Light reinforcement 13.07.38.6-2.92.9-2.8-2.9-2.92.82.62.82.81.2
Light reinforcement 21.01.62.1-1.31.4-1.4-1.4-1.31.41.21.21.20.5
Bone: marrow area0.20.51.01.0-0.81.00.70.7-0.3-0.5-0.4-0.40.7
Bone: maximum diameter0.91.73.1-0.51.0-0.6-1.2-1.21.61.51.61.61.7
Bone: maximum force2.13.77.12.7-2.32.62.12.0-1.4-1.5-1.4-1.41.1
Bone: maximum moment2.13.77.22.7-2.32.62.12.0-1.4-1.5-1.4-1.41.1
Mean time between licks in bursts0.61.52.1-1.51.4-1.4-1.2-1.41.21.11.21.2-0.3
Mean num. licks in bursts0.50.80.9-0.90.9-0.8-1.0-0.91.00.70.90.90.6
Cd content in liver0.60.60.9-0.90.8-0.8-0.8-0.90.90.71.00.80.1
Co content in liver2.52.94.6-2.12.0-2.1-1.9-1.81.61.51.61.5-0.4
Cu content in liver0.20.31.70.5-0.30.60.30.10.1-0.00.20.21.3
Fe content in liver0.10.10.30.1-0.20.20.40.3-0.5-0.5-0.3-0.4-0.5
K content in liver1.11.01.8-0.70.9-0.8-1.1-0.91.31.01.21.11.0
Mg content in liver1.21.31.9-0.91.1-1.0-1.2-1.11.41.31.21.10.8
Mn content in liver2.83.16.9-0.71.2-0.7-1.5-1.52.12.02.12.02.6
Na content in liver0.20.20.90.4-0.40.60.30.4-0.1-0.5-0.1-0.20.9
Rb content in liver0.30.31.90.5-0.30.50.10.00.40.20.30.31.4
Se content in liver0.00.00.0-0.00.0-0.1-0.1-0.10.10.20.10.1-0.0
Sr content in liver0.40.40.9-1.00.7-0.8-0.5-0.60.4-0.00.50.3-0.7
Zn content in liver2.72.95.8-2.42.0-2.4-1.8-1.71.21.21.11.1-1.6
Bone: minimum diameter0.20.31.50.8-0.40.70.20.20.20.30.20.21.2
Time in familiar zone, hab. session 13.83.75.1-2.32.2-2.3-2.1-2.11.81.81.71.8-0.3
Time in novel zone, hab. session 12.62.64.62.1-1.92.11.71.7-1.2-1.3-1.2-1.21.1
Total zone transitions, hab. session 10.60.82.70.00.4-0.1-0.7-0.61.01.10.91.01.7
Total locomotion distance, hab. session 12.23.16.4-0.71.3-0.8-1.7-1.62.22.02.02.02.5
Locomotion velocity, hab. session 12.13.04.4-1.01.4-1.0-1.7-1.72.11.91.91.92.1
Time in familiar zone, hab. session 24.54.87.6-2.72.5-2.8-2.4-2.41.91.91.91.9-0.8
Time in novel zone, hab. session 24.84.88.02.8-2.52.82.42.4-1.9-1.9-1.9-1.91.0
Total zone transitions, hab. session 20.70.93.71.3-0.91.40.70.5-0.1-0.0-0.00.01.9
Total locomotion distance, hab. session 20.40.62.1-0.10.4-0.0-0.6-0.60.80.90.80.91.4
Locomotion velocity, hab. session 20.60.83.20.00.40.1-0.6-0.71.01.01.01.01.8
Novel to familiar place preference ratio2.42.64.82.1-1.92.21.71.7-1.2-1.3-1.2-1.31.3
Novelty place preference1.51.73.21.7-1.51.81.31.3-0.8-1.0-0.9-0.91.3
Time in novel zone, NPP test2.02.13.81.9-1.72.01.51.5-1.1-1.2-1.1-1.11.2
Total zone transitions, NPP test0.60.81.71.3-1.11.30.80.9-0.5-0.4-0.6-0.51.0
Total locomotion distance, NPP test0.30.31.90.7-0.50.80.20.30.10.00.00.01.4
Locomotion velocity, NPP test0.20.31.80.4-0.20.5-0.1-0.00.40.30.30.31.3
Intraocular pressure0.30.42.1-0.70.3-0.7-0.2-0.0-0.4-0.2-0.5-0.4-1.4
Delta distance traveled before/after self-admin0.80.91.21.0-1.00.80.91.1-0.8-1.1-1.0-1.0-0.4
Delta ambulatory time before/after self-admin0.60.81.41.2-1.11.10.91.0-0.7-0.8-0.7-0.70.1
Parametrial fat weight0.40.81.41.2-1.01.00.91.1-0.7-0.9-0.9-0.90.2
Pavlov. Cond. lever latency0.40.52.5-0.30.0-0.40.30.3-0.6-0.8-0.7-0.7-1.6
Pavlov. Cond. magazine entry latency1.41.82.3-1.41.4-1.3-1.4-1.51.31.51.41.40.2
Pavlov. Cond. change in total contacts0.10.10.20.4-0.40.40.40.2-0.3-0.0-0.2-0.10.2
Pavlov. Cond. index score0.50.71.3-0.50.6-0.4-0.7-0.90.81.11.01.00.9
Pavlov. Cond. latency score0.70.91.7-0.40.6-0.3-0.8-0.91.01.31.11.21.3
Pavlov. Cond. lever contacts0.30.42.00.5-0.30.60.0-0.10.30.60.40.41.4
Pavlov. Cond. magazine entry number0.50.71.00.9-0.80.80.90.9-0.7-1.0-0.8-0.80.0
Pavlov. Cond. intertrial magazine entries0.10.21.0-0.60.4-0.5-0.1-0.2-0.1-0.2-0.0-0.1-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.4-0.60.7-0.5-0.8-0.90.91.21.01.10.8
Pavlov. Cond. response bias0.40.50.9-0.70.7-0.6-0.7-0.80.60.90.80.80.2
Pavlov. Cond. lever latency1.31.82.41.3-1.51.51.61.4-1.5-1.4-1.3-1.3-0.2
Pavlov. Cond. magazine entry latency1.92.43.2-1.41.7-1.7-1.8-1.51.71.71.51.50.4
Pavlov. Cond. change in total contacts0.71.11.6-1.21.2-1.3-1.2-1.11.11.10.90.9-0.1
Pavlov. Cond. index score1.82.43.2-1.61.7-1.8-1.8-1.61.61.71.51.50.1
Pavlov. Cond. latency score1.92.53.3-1.51.7-1.7-1.8-1.61.71.81.61.60.4
Pavlov. Cond. lever contacts1.21.72.4-1.41.5-1.6-1.5-1.31.41.31.21.2-0.1
Pavlov. Cond. magazine entry number2.32.83.71.6-1.81.71.91.7-1.8-1.9-1.7-1.7-0.5
Pavlov. Cond. intertrial magazine entries1.01.42.50.9-1.10.81.21.3-1.3-1.6-1.4-1.4-0.8
Pavlov. Cond. lever-magazine prob. diff.2.22.93.6-1.71.9-1.9-1.9-1.71.81.81.71.70.3
Pavlov. Cond. response bias2.02.74.0-1.81.9-2.0-1.9-1.71.71.61.51.5-0.2
Time in closed arm before self-admin0.20.21.20.6-0.30.60.20.10.20.20.20.21.1
Time in closed arm after self-admin0.10.10.20.0-0.1-0.10.40.3-0.2-0.5-0.3-0.4-0.3
Time in open arm before self-admin0.10.10.4-0.40.4-0.6-0.3-0.30.40.20.30.2-0.1
Time in open arm after self-admin2.42.63.21.5-1.61.61.61.7-1.8-1.7-1.7-1.7-0.7
Bone: periosteal estimation0.51.02.81.5-1.11.50.90.8-0.2-0.2-0.2-0.21.7
Bone: periosteal perimeter0.40.63.00.30.10.2-0.4-0.40.90.80.80.81.7
Bone: post-yield work0.40.71.01.0-0.80.90.81.0-0.6-0.9-0.8-0.90.0
Progressive ratio test 1 active lever presses0.20.31.00.3-0.40.30.50.6-0.4-1.0-0.4-0.6-0.4
Progressive ratio test 1 breakpoint0.20.31.10.3-0.40.30.50.6-0.4-1.0-0.4-0.6-0.4
Progressive ratio test 1 inactive lever presses0.50.71.2-1.01.0-1.1-0.8-0.80.80.50.80.70.0
Progressive ratio test 2 active lever presses0.20.20.4-0.60.6-0.6-0.5-0.40.40.10.50.40.1
Progressive ratio test 2 breakpoint0.30.30.5-0.70.7-0.7-0.6-0.50.50.20.60.50.1
Progressive ratio test 2 inactive lever presses0.00.10.40.00.1-0.0-0.1-0.00.3-0.20.30.10.6
Incentive Sensitization - Responses0.30.40.6-0.80.7-0.8-0.7-0.70.40.60.50.6-0.0
Incentive Sensitization - Breakpoint0.40.60.8-0.80.8-0.8-0.8-0.90.60.80.70.80.2
Sum of active levers in priming session hrs 5-60.10.10.2-0.40.4-0.4-0.3-0.40.20.30.20.3-0.1
Progressive ratio0.71.21.90.8-1.00.71.21.2-1.2-1.4-1.2-1.3-0.8
Food seeking constrained by brief footshock0.91.11.9-1.21.1-1.0-1.2-1.20.81.41.01.00.0
Seeking ratio, punishment vs. effort1.42.13.2-1.41.5-1.3-1.6-1.61.41.81.51.50.4
Retroperitoneal fat weight2.39.813.82.5-2.92.43.23.4-3.4-3.7-3.5-3.6-1.9
Reaction time number correct0.91.82.70.9-1.20.91.31.3-1.6-1.3-1.6-1.6-1.3
Reaction time mean minus median0.61.52.3-1.21.3-1.1-1.3-1.31.31.51.31.30.4
Reaction time mean minus median AUC0.92.33.7-0.71.2-0.7-1.4-1.51.81.91.81.81.7
Reaction time num false alarms0.71.01.51.0-1.00.91.01.1-1.0-1.2-1.2-1.2-0.4
Reaction time num false alarms AUC0.81.21.90.9-1.00.81.01.2-1.1-1.4-1.3-1.3-0.7
Reaction time trials correct on left0.91.82.70.9-1.20.91.31.3-1.6-1.3-1.6-1.6-1.3
Reaction time trials on left0.91.62.50.9-1.20.91.31.3-1.5-1.3-1.6-1.5-1.2
Reaction time mean1.11.73.1-0.81.1-0.6-1.3-1.41.41.81.61.61.2
Reaction time mean AUC0.61.01.9-0.40.7-0.3-0.9-1.01.11.41.21.21.1
Median of all reaction times0.81.12.0-0.50.8-0.3-0.9-1.11.11.41.31.31.2
Reaction time omissions0.10.20.70.00.10.0-0.2-0.30.60.60.60.50.8
Reaction time false alarm rate0.20.20.40.6-0.50.50.40.5-0.3-0.6-0.4-0.40.2
Reaction time premature initiation rate0.91.32.8-1.71.4-1.7-1.2-1.10.80.50.80.7-0.9
Reaction time premature initiations0.40.72.6-1.30.8-1.2-0.5-0.4-0.1-0.2-0.0-0.1-1.6
Std. dev. reaction times0.61.11.9-0.70.9-0.7-1.1-1.11.31.41.21.20.9
Reaction time trials completed0.91.62.50.9-1.20.91.31.3-1.5-1.3-1.6-1.5-1.2
Reaction time trials AUC1.12.03.10.9-1.30.91.41.4-1.7-1.4-1.8-1.7-1.4
Run reversals in cocaine runway, females2.72.73.6-1.21.6-1.2-1.8-1.81.81.91.91.91.1
Run reversals in cocaine runway, males2.92.94.1-1.41.7-1.2-1.7-1.81.92.02.02.01.2
Latency to leave start box in cocaine runway0.40.41.91.0-0.70.80.20.40.40.00.10.11.4
Latency to leave start box in cocaine runway, F0.70.83.41.2-0.81.20.30.30.40.20.20.21.8
Latency to leave start box in cocaine runway, M0.10.10.3-0.1-0.0-0.30.00.2-0.1-0.3-0.3-0.4-0.5
Std. dev. time between licks in bursts1.11.42.1-0.81.0-0.7-1.1-1.21.51.41.41.41.2
Total sessions with >9 infusions0.00.10.2-0.10.2-0.20.1-0.00.3-0.40.20.00.3
Short access day 1 total inactive lever presses0.50.61.4-1.11.0-1.2-0.8-0.80.60.40.40.5-0.5
Short access day 10 total inactive lever presses0.30.72.5-1.20.8-1.2-0.4-0.3-0.2-0.1-0.2-0.2-1.6
Short access day 1 total infusions0.00.10.1-0.20.2-0.30.1-0.10.3-0.30.20.10.3
Short access day 10 total infusions0.00.00.1-0.10.1-0.10.10.10.0-0.3-0.0-0.1-0.2
Short access total infusions0.10.10.40.2-0.10.20.40.3-0.0-0.6-0.1-0.20.4
Short access day 1 locomotion1.11.42.5-1.51.5-1.6-1.2-1.11.20.51.11.0-0.4
Short access day 10 total locomotion2.03.88.2-2.92.4-2.8-1.9-1.91.50.81.31.3-1.3
Short access total locomotion0.91.12.4-1.51.4-1.5-1.0-1.01.00.20.90.8-0.5
One hour access (0.3 mA shock)0.10.10.3-0.0-0.1-0.00.30.3-0.5-0.5-0.4-0.5-0.4
Compulsive drug intake0.00.00.10.00.00.0-0.10.00.20.20.20.00.4
One hour access (shock baseline)0.10.20.5-0.70.6-0.7-0.4-0.50.20.00.30.3-0.3
Social response proportion0.60.71.1-0.70.8-0.5-0.9-1.00.81.01.01.10.6
Social responses8.110.412.6-3.03.3-3.0-3.5-3.53.53.43.53.61.4
Social time1.31.82.51.1-1.41.31.51.4-1.6-1.3-1.4-1.4-0.7
Soleus weight6.017.721.64.5-4.64.54.64.5-4.3-4.2-4.3-4.2-0.7
Bone: stiffness2.94.88.12.8-2.52.82.42.3-1.9-1.9-1.8-1.80.7
Tibialis anterior weight1.44.75.82.4-2.42.42.42.3-2.3-2.1-2.2-2.1-0.4
Time to tail flick, vehicle, before self-admin1.71.72.5-1.11.2-1.0-1.2-1.51.41.41.51.61.2
Time to tail flick, vehicle, after self-admin0.30.41.7-0.70.5-0.9-0.4-0.3-0.10.3-0.3-0.2-1.3
Time to tail flick, test, before self-admin1.11.11.9-0.50.8-0.5-1.0-1.01.41.31.21.21.3
Time to tail flick, test, after self-admin0.10.10.40.10.0-0.0-0.1-0.10.40.20.20.20.6
Delta time to tail flick, vehicle, before/after SA2.62.53.81.1-1.41.01.41.6-1.8-1.5-1.9-1.9-1.7
Delta time to tail flick, test, before/after SA0.40.41.5-0.2-0.1-0.20.30.3-0.7-0.6-0.7-0.7-1.2
Tibia length0.61.62.5-1.61.5-1.5-1.5-1.31.21.11.21.0-0.2
Ambulatory time before self-admin0.30.50.7-0.80.8-0.7-0.7-0.80.60.60.60.60.1
Ambulatory time after self-admin0.00.00.10.2-0.20.20.10.2-0.1-0.3-0.1-0.10.1
Bone: tissue strength4.24.25.92.4-2.32.42.32.2-1.8-2.1-1.9-1.90.3
Total heroin consumption1.82.12.7-1.31.5-1.3-1.6-1.61.61.61.51.60.8
Bone: trabecular number0.50.93.00.10.5-0.2-0.9-0.51.31.11.01.01.7
Bone: trabecular spacing0.91.26.2-0.6-0.1-0.50.50.4-1.2-1.2-1.0-1.0-2.5
Bone: trabecular thickness1.51.911.41.4-0.51.2-0.0-0.01.11.10.90.93.4
Bone: trabecular tissue density4.36.37.72.3-2.62.32.72.7-2.7-2.7-2.8-2.7-1.2
Water consumed over 24 hours0.50.71.51.2-1.01.10.80.9-0.5-0.6-0.6-0.70.8
Number of responses in last shaping day3.43.76.8-2.62.4-2.6-2.0-2.01.71.31.71.6-0.5