Hub : Genes

Tmem198b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tmem198b 0.03 0.03 8.8e-03 0.02 0.02 0.01 0.02 2.1e-03 5.8e-03 4.0e-02 3.8e-03
2 Brain mRNA stability Tmem198b 0.2 0.12 7.2e-11 0.08 0.09 0.1 0.1 9.6e-08 6.1e-09 6.7e-10 1.7e-09
3 OFC gene expression Tmem198b 0.24 0.16 2.4e-03 0.05 0.02 0.04 0.04 2.3e-02 9.2e-02 3.8e-02 4.9e-02
4 Brain gene expression Tmem198b 0.11 0.07 4.9e-07 0.04 0.04 0.04 0.04 1.0e-04 9.9e-05 6.0e-05 4.3e-05
5 NAcc gene expression Tmem198b 0.04 0.03 1.9e-05 0.03 0.03 0.03 0.03 1.9e-05 7.9e-06 2.2e-05 7.8e-06
6 pVTA mRNA stability Tmem198b 0.06 0.04 1.3e-03 0.04 0.04 0.04 0.04 4.6e-04 5.8e-04 7.0e-04 7.7e-04
7 NAcc mRNA stability Tmem198b 0.03 0.02 1.8e-04 0.02 0.02 0.02 0.02 1.1e-04 1.6e-04 1.4e-04 1.6e-04
8 BLA mRNA stability Tmem198b 0.05 0.04 6.1e-03 0.04 0.02 0.01 0.02 3.7e-03 4.1e-02 8.9e-02 2.4e-02
9 PL mRNA stability Tmem198b 0.06 0.04 1.3e-05 0.03 0.03 0.04 0.04 2.9e-04 3.8e-04 7.5e-05 2.5e-05
10 OFC mRNA stability Tmem198b 0.16 0.13 9.9e-03 0.09 0.07 -0.01 0.08 4.5e-03 7.6e-03 6.6e-01 5.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.51.06.1-1.10.4-0.90.2-0.2-0.8-0.5-0.50.5-2.5
Area under the delay curve0.10.20.4-0.50.6-0.60.50.50.40.30.3-0.4-0.2
BMI with tail7.927.733.2-5.55.7-5.55.85.65.45.45.4-5.41.1
BMI without tail1.37.08.7-2.82.8-2.63.02.82.62.82.8-2.80.7
Body weight1.66.88.6-2.52.6-2.42.92.72.72.82.9-2.91.1
Weight adjusted by age0.00.00.10.3-0.20.3-0.0-0.1-0.10.30.0-0.10.3
Bone surface1.52.913.9-0.7-0.3-0.4-0.7-1.2-2.1-1.6-1.61.6-3.7
Bone volume1.32.514.1-1.10.0-0.8-0.4-0.9-1.7-1.4-1.41.3-3.7
Breakpoint value in progressive ratio session0.71.21.81.3-1.31.3-1.3-1.2-0.9-0.9-1.01.0-0.1
Number of licking bursts1.44.35.2-1.92.1-1.82.22.32.32.02.3-2.31.4
Context. condit. distance diff. score0.20.30.4-0.40.6-0.60.50.60.60.50.5-0.50.2
Locomotion velocity, session 10.40.52.1-1.00.6-1.00.20.3-0.0-0.3-0.10.2-1.4
Locomotion distance, session 10.70.83.3-0.2-0.3-0.2-0.6-0.6-0.9-1.1-1.01.1-1.8
Locomotion velocity, session 22.22.64.40.7-1.20.8-1.6-1.6-1.9-1.9-1.91.9-2.1
Locomotion distance, session 22.63.65.31.0-1.61.1-1.8-1.9-2.2-2.3-2.22.2-2.1
Locomotion velocity, session 34.24.85.92.4-2.42.3-2.4-2.4-2.2-2.2-2.22.3-0.2
Locomotion distance, session 30.00.10.10.3-0.20.3-0.3-0.2-0.1-0.2-0.20.20.2
Stereotopy head waving bouts, day 35.86.98.42.5-2.82.7-2.8-2.9-2.9-2.7-2.72.7-1.0
Stereotopy head waving duration, day 34.65.76.82.4-2.62.5-2.5-2.6-2.6-2.4-2.52.5-0.8
Locomotion velocity, session 70.20.20.30.2-0.30.0-0.5-0.4-0.4-0.5-0.50.6-0.6
Locomotion distance, session 70.20.20.90.00.2-0.10.30.50.60.50.4-0.50.9
Stereotopy head waving bouts, day 71.01.22.10.4-0.80.5-1.0-1.1-1.2-1.3-1.31.3-1.4
Stereotopy head waving duration, day 71.01.23.00.3-0.70.3-1.0-1.0-1.2-1.3-1.31.3-1.7
Locomotion velocity, session 81.41.74.00.3-0.80.4-1.1-1.1-1.5-1.6-1.51.5-2.0
Locomotion distance, session 80.30.40.60.4-0.50.3-0.6-0.6-0.7-0.7-0.80.7-0.7
Degree of sensitization distance0.50.60.8-0.80.8-0.90.80.90.80.70.7-0.70.0
Degree of sensitization stereotypy0.20.20.9-0.70.5-0.80.20.30.10.0-0.00.0-1.0
Conditioned locomotion1.41.62.9-0.61.0-0.71.21.31.61.51.4-1.41.7
Cocaine response after cond. corrected1.92.93.9-1.21.5-1.21.71.82.01.91.9-1.91.7
Cocaine response after cond. not corrected2.03.04.0-1.11.5-1.11.71.82.02.02.0-2.01.8
Cocaine response before conditioning0.60.71.00.8-0.80.9-0.9-1.0-0.9-0.8-0.80.8-0.6
Saline control response0.81.21.7-0.81.0-0.71.21.11.11.31.3-1.30.9
Bone: connectivity density0.30.53.2-0.70.1-0.40.1-0.3-0.7-0.4-0.40.4-1.8
Bone: cortical apparent density0.71.11.6-1.21.2-1.31.11.21.11.10.9-0.90.0
Bone: cortical area0.50.82.6-1.41.0-1.30.60.50.10.10.1-0.1-1.6
Bone: cortical porosity0.10.10.6-0.1-0.0-0.1-0.2-0.3-0.4-0.2-0.30.3-0.8
Bone: cortical porosity0.20.21.4-0.50.2-0.40.0-0.1-0.4-0.1-0.20.2-1.2
Bone: cortical thickness0.81.42.9-1.71.4-1.71.21.10.90.90.8-0.8-0.9
Bone: cortical thickness0.70.91.3-0.80.9-0.91.01.11.10.91.0-1.00.7
Bone: cortical tissue density0.50.81.1-1.01.0-1.10.91.00.90.90.7-0.80.0
Condit. Reinf. active minus inactive responses2.22.53.01.6-1.71.5-1.7-1.7-1.6-1.7-1.71.7-0.4
Condit. Reinf. active-inactive response ratio0.40.40.91.0-0.80.9-0.6-0.7-0.5-0.4-0.50.40.5
Condit. Reinf. active responses3.24.15.41.7-2.01.7-2.2-2.1-2.2-2.3-2.22.3-1.3
Condit. Reinf. inactive responses1.62.13.20.8-1.20.8-1.5-1.4-1.6-1.8-1.71.7-1.6
Incentive salience index mean1.41.92.81.0-1.20.9-1.5-1.4-1.5-1.7-1.61.6-1.1
Condit. Reinf. lever presses0.60.93.5-0.2-0.2-0.3-0.6-0.6-0.9-1.2-1.01.0-1.9
Condit. Reinf. active minus inactive responses1.92.95.02.2-2.02.2-1.8-1.7-1.4-1.4-1.41.40.8
Condit. Reinf. active-inactive response ratio0.50.82.61.4-1.01.3-0.7-0.5-0.1-0.2-0.30.21.6
Condit. Reinf. active responses1.92.83.81.8-1.92.0-1.7-1.8-1.7-1.6-1.61.5-0.0
Condit. Reinf. inactive responses0.50.81.30.5-0.80.7-0.8-1.0-1.2-1.0-0.90.9-0.8
Condit. Reinf. lever presses2.33.45.42.2-2.22.3-1.9-2.0-1.8-1.6-1.71.60.5
Condit. Reinf. lever reinforcers received1.42.03.31.7-1.71.8-1.4-1.5-1.4-1.3-1.31.20.3
Conditioned reinforcement - actives0.10.20.50.6-0.60.7-0.4-0.5-0.5-0.0-0.50.30.1
Conditioned reinforcement - inactives0.10.30.90.5-0.20.50.20.10.40.90.3-0.50.8
Conditioned locomotion3.75.56.72.4-2.62.5-2.5-2.6-2.6-1.9-2.52.5-0.8
Patch foraging indifference point 0 sec1.64.56.1-2.52.4-2.42.32.21.92.22.1-2.0-0.3
Patch foraging indifference point AUC0.30.71.11.1-1.01.0-0.9-0.8-0.8-0.8-0.80.70.2
Delay disc. indifference point, 0s delay2.02.24.8-2.21.8-2.21.51.40.90.80.9-0.9-1.5
Delay disc. indifference point, 16s delay0.10.10.30.3-0.30.1-0.4-0.3-0.3-0.6-0.50.5-0.3
Delay disc. indifference point, 2s delay0.60.71.4-1.11.0-1.20.80.80.60.30.5-0.5-0.8
Delay disc. indifference point, 24s delay0.40.60.9-0.80.9-1.00.90.70.80.80.7-0.80.0
Delay disc. indifference point, 4s delay0.30.31.2-0.1-0.2-0.0-0.3-0.3-0.7-0.7-0.60.6-1.1
Delay disc. indifference point, 8s delay0.30.50.8-0.40.6-0.40.80.60.80.80.8-0.90.8
Indifference point function ln k0.00.00.0-0.00.10.00.00.10.10.00.1-0.10.1
Indifference point function log k0.00.00.0-0.00.10.00.00.10.10.00.1-0.10.1
Patch foraging total patch changes 0 sec1.33.95.2-2.32.2-2.22.12.01.82.02.0-1.9-0.3
Patch foraging total patch changes 12 sec2.02.63.6-1.41.6-1.41.81.61.61.91.8-1.90.8
Patch foraging total patch changes 18 sec0.00.10.2-0.30.3-0.40.30.30.20.50.3-0.3-0.3
Patch foraging total patch changes 24 sec0.20.71.2-1.01.0-1.10.90.80.70.80.7-0.7-0.5
Patch foraging total patch changes 6 sec1.11.92.6-1.61.6-1.61.51.41.21.31.3-1.3-0.1
Patch foraging time to switch 0 sec0.10.51.3-1.10.9-1.00.70.50.20.40.3-0.4-0.8
Patch foraging water rate 0 sec0.20.91.4-0.40.7-0.40.91.01.21.11.2-1.11.2
Patch foraging water rate 12 sec0.31.01.8-0.40.7-0.50.91.11.31.11.2-1.21.2
Patch foraging water rate 18 sec0.51.05.40.9-0.30.80.20.30.90.80.9-0.92.3
Patch foraging water rate 24 sec2.63.68.1-0.41.2-0.51.71.82.42.12.3-2.32.8
Patch foraging water rate 6 sec0.71.02.61.6-1.21.6-0.8-0.7-0.2-0.2-0.20.31.5
Seeking ratio, delayed vs. immediate footshock1.72.43.21.4-1.61.4-1.6-1.7-1.8-1.6-1.71.7-1.0
Distance traveled before self-admin0.71.62.01.3-1.41.3-1.4-1.4-1.2-1.4-1.21.3-0.4
Distance traveled after self-admin0.00.00.0-0.20.2-0.10.20.10.10.20.2-0.20.0
Extensor digitorum longus weight5.321.124.9-4.44.8-4.25.04.94.94.95.0-5.02.2
Bone: elastic displacement0.00.00.00.0-0.00.0-0.1-0.0-0.10.1-0.00.0-0.1
Bone: elastic work0.71.01.8-1.31.2-1.31.01.00.60.80.8-0.8-0.6
Bone: endosteal estimation0.20.51.2-1.10.9-1.10.80.60.40.50.5-0.5-0.8
Bone: endosteal perimeter0.51.21.90.5-0.80.6-1.0-1.2-1.4-1.2-1.21.3-1.4
Epididymis fat weight0.10.31.50.8-0.50.6-0.1-0.10.30.20.1-0.21.2
Delta time in closed arm before/after self-admin1.91.84.7-0.10.6-0.11.11.11.51.61.6-1.72.2
Delta time in open arm before/after self-admin1.31.62.2-1.31.4-1.51.31.41.41.21.2-1.20.2
Diff in mean of infusions in LGA sessions1.42.53.31.8-1.81.8-1.7-1.7-1.5-1.5-1.51.5-0.0
Delay discount exponential model param0.10.10.30.4-0.40.5-0.4-0.3-0.3-0.2-0.30.30.2
Extinction: sum of active levers before priming1.01.52.91.7-1.51.6-1.4-1.2-0.9-0.9-0.91.10.8
Active lever presses in extinction session 60.30.30.50.3-0.40.3-0.6-0.5-0.5-0.5-0.60.7-0.5
Bone: final force2.03.36.9-2.62.2-2.61.91.71.21.31.2-1.2-1.4
Bone: final moment2.03.36.9-2.62.2-2.61.91.71.21.31.2-1.2-1.4
Food consumed during 24 hour testing period0.20.50.7-0.80.7-0.80.80.80.70.60.7-0.70.1
Glucose1.92.93.5-1.71.8-1.81.81.91.91.81.7-1.80.4
Heart weight0.20.40.91.0-0.80.9-0.6-0.6-0.4-0.2-0.40.30.7
Delay discount hyperbolic model param0.30.40.80.8-0.80.9-0.7-0.6-0.5-0.3-0.50.50.4
Intermittent access intake day 1-15 change0.21.33.21.8-1.51.8-1.1-1.3-0.7-0.4-0.70.60.7
Intermittent access intake escalation0.21.12.91.7-1.41.7-0.9-1.1-0.6-0.3-0.60.50.7
Intermittent access intake escalation 20.61.02.21.5-1.31.5-1.0-1.1-0.7-0.6-0.80.70.3
Intermitt. access day 1 inactive lever presses0.10.82.41.4-1.01.5-0.6-0.5-0.10.0-0.00.11.5
Intermitt. access day 15 inactive lever presses0.20.91.61.3-1.11.3-1.0-1.0-0.6-0.9-0.70.70.2
Intermitt. access escalation Index0.10.20.8-0.50.3-0.50.1-0.1-0.3-0.1-0.20.3-0.9
Intermittent access day 1 total infusions0.00.10.2-0.00.1-0.10.20.20.20.50.2-0.30.4
Intermittent access day 15 total infusions0.10.30.50.7-0.70.7-0.4-0.6-0.4-0.1-0.50.4-0.0
Intermittent access terminal intake (last 3 days)0.30.50.70.6-0.70.6-0.7-0.8-0.8-0.5-0.80.7-0.6
Intermittent access total infusions0.00.00.10.2-0.20.2-0.1-0.3-0.20.2-0.20.1-0.1
Intermittent access day 1 locomotion0.10.21.00.3-0.10.30.10.20.30.60.3-0.31.0
Intermittent access day 15 total locomotion0.31.12.51.6-1.31.6-1.0-1.0-0.7-0.1-0.80.70.5
Intermittent access total locomotion0.30.40.90.9-0.80.9-0.5-0.6-0.50.1-0.50.40.4
Intermittent access standard deviation0.52.43.21.6-1.71.6-1.6-1.8-1.7-1.3-1.71.5-0.6
Left kidney weight0.00.10.2-0.00.2-0.10.30.20.40.20.3-0.30.5
Right kidney weight0.00.30.60.7-0.60.7-0.5-0.4-0.3-0.4-0.40.40.7
Cocaine induced anxiety0.82.33.31.0-1.30.9-1.5-1.6-1.8-1.7-1.71.8-1.6
Post-drug Anxiety1.41.64.60.3-0.80.3-1.0-1.2-1.5-1.2-1.51.5-2.2
Baseline Anxiety0.00.00.1-0.10.1-0.10.20.10.10.10.1-0.2-0.1
Tail length2.211.615.43.8-3.83.9-3.6-3.7-3.5-3.3-3.33.30.0
Length with tail1.14.98.02.8-2.72.8-2.3-2.4-2.1-1.9-1.91.80.6
Length without tail0.20.91.3-0.60.8-0.71.01.01.11.11.1-1.10.8
Times rat made contact with spout1.51.72.3-1.01.2-1.11.41.31.51.41.5-1.50.9
Lifetime Intake0.10.10.4-0.20.2-0.20.30.10.10.60.1-0.2-0.3
Liver weight, left0.40.81.0-0.90.9-1.00.91.01.00.80.9-0.80.4
Liver weight, right0.00.10.40.2-0.10.20.10.00.10.20.1-0.20.6
Locomotor activity3.04.76.01.8-2.11.8-2.3-2.3-2.4-2.3-2.42.5-1.4
Locomotor testing distance1.12.73.51.4-1.61.3-1.7-1.7-1.9-1.7-1.91.8-1.1
Locomotor testing rearing0.00.00.20.1-0.00.20.10.10.10.30.2-0.20.4
Locomotion in novel chamber0.00.00.00.0-0.00.00.0-0.1-0.10.1-0.0-0.0-0.0
Locomotion in novel chamber post-restriction1.75.16.32.5-2.52.2-2.5-2.3-2.2-2.5-2.32.3-0.4
Fecal boli incidents, locomotor time 10.51.42.0-0.91.1-0.91.11.31.41.21.4-1.31.0
Change in fecal boli incidents, locomotor task1.01.02.20.4-0.70.4-0.9-0.9-1.2-1.2-1.21.1-1.5
Time >=10cm from walls, locomotor time 10.40.51.4-1.00.8-1.00.60.50.20.30.3-0.2-1.2
Bouts of movement, locomotor time 10.60.81.11.0-1.01.1-0.9-1.0-0.8-0.8-0.80.70.2
Total resting periods, locomotor time 11.31.41.91.3-1.31.4-1.3-1.4-1.2-1.2-1.21.1-0.0
Rest time, locomotor task time 10.30.50.70.5-0.60.5-0.7-0.7-0.9-0.8-0.80.7-0.7
Distance moved, locomotor task time 10.20.61.5-1.10.8-1.10.60.60.30.40.2-0.2-1.2
Vertical activity count, locomotor time 10.10.81.1-0.80.9-0.90.90.91.01.10.9-0.80.3
Time >=10cm from walls, locomotor time 20.41.11.8-0.81.0-0.81.11.11.11.31.2-1.10.8
Bouts of movement, locomotor time 20.10.51.20.1-0.40.2-0.4-0.8-0.8-0.9-0.70.7-1.1
Total resting periods, locomotor time 20.10.51.60.0-0.30.1-0.5-0.8-0.8-0.9-0.70.7-1.3
Rest time, locomotor task time 20.10.20.9-0.1-0.1-0.1-0.2-0.2-0.5-0.4-0.50.5-1.0
Distance moved, locomotor task time 20.10.10.70.3-0.10.20.10.10.30.50.3-0.30.9
Vertical activity count, locomotor time 20.71.52.4-0.71.0-0.71.11.21.51.61.4-1.41.4
Light reinforcement 11.67.49.22.9-2.92.8-2.9-3.0-2.8-2.6-2.82.8-1.2
Light reinforcement 20.71.62.21.3-1.41.4-1.3-1.5-1.4-1.2-1.21.2-0.5
Bone: marrow area0.20.51.0-1.00.8-1.00.70.60.30.50.4-0.4-0.7
Bone: maximum diameter0.91.83.10.5-1.00.6-1.2-1.4-1.6-1.5-1.61.6-1.7
Bone: maximum force1.83.67.1-2.72.3-2.62.01.91.41.51.4-1.4-1.1
Bone: maximum moment1.93.77.2-2.72.3-2.62.01.91.41.51.4-1.4-1.1
Mean time between licks in bursts0.21.52.11.5-1.41.4-1.4-1.3-1.2-1.1-1.21.20.3
Mean num. licks in bursts0.30.81.10.9-0.90.8-0.9-1.1-1.0-0.7-0.90.9-0.6
Cd content in liver0.60.70.90.9-0.80.8-0.9-0.9-0.9-0.7-1.00.8-0.1
Co content in liver2.52.94.62.1-2.02.1-1.8-1.8-1.6-1.5-1.61.50.4
Cu content in liver0.20.21.7-0.50.3-0.60.10.1-0.10.0-0.20.2-1.3
Fe content in liver0.10.10.3-0.10.2-0.20.30.40.50.50.3-0.40.5
K content in liver1.11.11.80.7-0.90.8-0.9-1.2-1.3-1.0-1.21.1-1.0
Mg content in liver1.11.31.90.9-1.11.0-1.1-1.2-1.4-1.3-1.21.1-0.8
Mn content in liver2.83.26.90.7-1.20.7-1.6-1.7-2.1-2.0-2.12.0-2.6
Na content in liver0.20.20.9-0.40.4-0.60.40.30.10.50.1-0.2-0.9
Rb content in liver0.30.31.9-0.50.3-0.50.0-0.1-0.4-0.2-0.30.3-1.4
Se content in liver0.00.00.00.0-0.00.1-0.1-0.2-0.1-0.2-0.10.10.0
Sr content in liver0.40.40.91.0-0.70.8-0.6-0.6-0.40.0-0.50.30.7
Zn content in liver2.52.95.82.4-2.02.4-1.7-1.6-1.2-1.2-1.11.11.6
Bone: minimum diameter0.20.31.5-0.80.4-0.70.20.0-0.2-0.3-0.20.2-1.2
Time in familiar zone, hab. session 13.33.65.12.3-2.22.3-2.1-2.0-1.8-1.8-1.71.80.3
Time in novel zone, hab. session 12.32.54.6-2.11.9-2.11.71.61.21.31.2-1.2-1.1
Total zone transitions, hab. session 10.60.82.7-0.0-0.40.1-0.6-0.7-1.0-1.1-0.91.0-1.7
Total locomotion distance, hab. session 12.23.16.40.7-1.30.8-1.6-1.8-2.2-2.0-2.02.0-2.5
Locomotion velocity, hab. session 12.13.04.41.0-1.41.0-1.7-1.8-2.1-1.9-1.91.9-2.1
Time in familiar zone, hab. session 24.24.87.62.7-2.52.8-2.4-2.3-1.9-1.9-1.91.90.8
Time in novel zone, hab. session 24.44.88.0-2.82.5-2.82.42.31.91.91.9-1.9-1.0
Total zone transitions, hab. session 20.70.93.7-1.30.9-1.40.50.50.10.00.00.0-1.9
Total locomotion distance, hab. session 20.40.62.10.1-0.40.0-0.6-0.6-0.8-0.9-0.80.9-1.4
Locomotion velocity, hab. session 20.60.83.2-0.0-0.4-0.1-0.7-0.7-1.0-1.0-1.01.0-1.8
Novel to familiar place preference ratio2.02.64.8-2.11.9-2.21.71.51.21.31.2-1.3-1.3
Novelty place preference1.31.63.2-1.71.5-1.81.31.20.81.00.9-0.9-1.3
Time in novel zone, NPP test1.72.13.8-1.91.7-2.01.51.41.11.21.1-1.1-1.2
Total zone transitions, NPP test0.50.81.7-1.31.1-1.30.80.80.50.40.6-0.5-1.0
Total locomotion distance, NPP test0.20.31.9-0.70.5-0.80.30.2-0.1-0.0-0.00.0-1.4
Locomotion velocity, NPP test0.20.31.8-0.40.2-0.5-0.0-0.1-0.4-0.3-0.30.3-1.3
Intraocular pressure0.20.42.10.7-0.30.7-0.00.00.40.20.5-0.41.4
Delta distance traveled before/after self-admin0.80.91.2-1.01.0-0.81.11.00.81.11.0-1.00.4
Delta ambulatory time before/after self-admin0.50.81.4-1.21.1-1.11.00.90.70.80.7-0.7-0.1
Parametrial fat weight0.40.81.4-1.21.0-1.01.10.90.70.90.9-0.9-0.2
Pavlov. Cond. lever latency0.40.52.50.3-0.00.40.30.40.60.80.7-0.71.6
Pavlov. Cond. magazine entry latency1.41.82.31.4-1.41.3-1.5-1.4-1.3-1.5-1.41.4-0.2
Pavlov. Cond. change in total contacts0.10.10.2-0.40.4-0.40.20.30.30.00.2-0.1-0.2
Pavlov. Cond. index score0.50.71.30.5-0.60.4-0.9-0.8-0.8-1.1-1.01.0-0.9
Pavlov. Cond. latency score0.70.91.70.4-0.60.3-0.9-0.9-1.0-1.3-1.11.2-1.3
Pavlov. Cond. lever contacts0.30.42.0-0.50.3-0.6-0.1-0.1-0.3-0.6-0.40.4-1.4
Pavlov. Cond. magazine entry number0.50.71.0-0.90.8-0.80.90.80.71.00.8-0.8-0.0
Pavlov. Cond. intertrial magazine entries0.10.21.00.6-0.40.5-0.2-0.00.10.20.0-0.11.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.40.6-0.70.5-0.9-0.9-0.9-1.2-1.01.1-0.8
Pavlov. Cond. response bias0.40.50.90.7-0.70.6-0.8-0.7-0.6-0.9-0.80.8-0.2
Pavlov. Cond. lever latency1.31.82.3-1.31.5-1.51.41.51.51.41.3-1.30.2
Pavlov. Cond. magazine entry latency1.62.33.01.4-1.71.7-1.5-1.7-1.7-1.7-1.51.5-0.4
Pavlov. Cond. change in total contacts0.41.11.61.2-1.21.3-1.1-1.1-1.1-1.1-0.90.90.1
Pavlov. Cond. index score1.52.43.21.6-1.71.8-1.6-1.7-1.6-1.7-1.51.5-0.1
Pavlov. Cond. latency score1.62.53.21.5-1.71.7-1.6-1.7-1.7-1.8-1.61.6-0.4
Pavlov. Cond. lever contacts1.11.72.41.4-1.51.6-1.3-1.4-1.4-1.3-1.21.20.1
Pavlov. Cond. magazine entry number2.22.83.7-1.61.8-1.71.71.81.81.91.7-1.70.5
Pavlov. Cond. intertrial magazine entries0.71.42.5-0.91.1-0.81.31.21.31.61.4-1.40.8
Pavlov. Cond. lever-magazine prob. diff.1.92.93.51.7-1.91.9-1.7-1.8-1.8-1.8-1.71.7-0.3
Pavlov. Cond. response bias2.02.74.01.8-1.92.0-1.7-1.8-1.7-1.6-1.51.50.2
Time in closed arm before self-admin0.10.21.2-0.60.3-0.60.10.1-0.2-0.2-0.20.2-1.1
Time in closed arm after self-admin0.10.10.2-0.00.10.10.30.20.20.50.3-0.40.3
Time in open arm before self-admin0.10.10.40.4-0.40.6-0.3-0.4-0.4-0.2-0.30.20.1
Time in open arm after self-admin2.42.63.2-1.51.6-1.61.71.71.81.71.7-1.70.7
Bone: periosteal estimation0.41.02.8-1.51.1-1.50.80.60.20.20.2-0.2-1.7
Bone: periosteal perimeter0.30.63.0-0.3-0.1-0.2-0.4-0.6-0.9-0.8-0.80.8-1.7
Bone: post-yield work0.40.71.0-1.00.8-0.91.00.80.60.90.8-0.9-0.0
Progressive ratio test 1 active lever presses0.20.31.0-0.30.4-0.30.60.40.41.00.4-0.60.4
Progressive ratio test 1 breakpoint0.20.31.1-0.30.4-0.30.60.40.41.00.4-0.60.4
Progressive ratio test 1 inactive lever presses0.30.71.21.0-1.01.1-0.8-0.9-0.8-0.5-0.80.7-0.0
Progressive ratio test 2 active lever presses0.20.20.40.6-0.60.6-0.4-0.6-0.4-0.1-0.50.4-0.1
Progressive ratio test 2 breakpoint0.20.30.50.7-0.70.7-0.5-0.6-0.5-0.2-0.60.5-0.1
Progressive ratio test 2 inactive lever presses0.00.10.4-0.0-0.10.0-0.0-0.3-0.30.2-0.30.1-0.6
Incentive Sensitization - Responses0.10.40.60.8-0.70.8-0.7-0.7-0.4-0.6-0.50.60.0
Incentive Sensitization - Breakpoint0.20.60.80.8-0.80.8-0.9-0.8-0.6-0.8-0.70.8-0.2
Sum of active levers in priming session hrs 5-60.10.10.20.4-0.40.4-0.4-0.3-0.2-0.3-0.20.30.1
Progressive ratio0.41.21.9-0.81.0-0.71.21.11.21.41.2-1.30.8
Food seeking constrained by brief footshock0.91.11.91.2-1.11.0-1.2-1.0-0.8-1.4-1.01.0-0.0
Seeking ratio, punishment vs. effort0.92.03.21.4-1.51.3-1.6-1.4-1.4-1.8-1.51.5-0.4
Retroperitoneal fat weight2.29.813.8-2.52.9-2.43.43.33.43.73.5-3.61.9
Reaction time number correct0.51.82.7-0.91.2-0.91.31.41.61.31.6-1.61.3
Reaction time mean minus median0.21.52.31.2-1.31.1-1.3-1.3-1.3-1.5-1.31.3-0.4
Reaction time mean minus median AUC0.32.33.70.7-1.20.7-1.5-1.4-1.8-1.9-1.81.8-1.7
Reaction time num false alarms0.61.01.5-1.01.0-0.91.11.01.01.21.2-1.20.4
Reaction time num false alarms AUC0.51.21.9-0.91.0-0.81.21.01.11.41.3-1.30.7
Reaction time trials correct on left0.51.82.7-0.91.2-0.91.31.41.61.31.6-1.61.3
Reaction time trials on left0.51.72.5-0.91.2-0.91.31.41.51.31.6-1.51.2
Reaction time mean0.81.73.10.8-1.10.6-1.4-1.3-1.4-1.8-1.61.6-1.2
Reaction time mean AUC0.41.01.90.4-0.70.3-1.0-0.9-1.1-1.4-1.21.2-1.1
Median of all reaction times0.71.12.00.5-0.80.3-1.1-1.0-1.1-1.4-1.31.3-1.2
Reaction time omissions0.10.20.7-0.0-0.1-0.0-0.3-0.4-0.6-0.6-0.60.5-0.8
Reaction time false alarm rate0.20.20.4-0.60.5-0.50.50.40.30.60.4-0.4-0.2
Reaction time premature initiation rate0.81.32.81.7-1.41.7-1.1-1.1-0.8-0.5-0.80.70.9
Reaction time premature initiations0.20.72.61.3-0.81.2-0.4-0.40.10.20.0-0.11.6
Std. dev. reaction times0.31.11.90.7-0.90.7-1.1-1.1-1.3-1.4-1.21.2-0.9
Reaction time trials completed0.51.72.5-0.91.2-0.91.31.41.51.31.6-1.51.2
Reaction time trials AUC0.62.13.1-0.91.3-0.91.41.51.71.41.8-1.71.4
Run reversals in cocaine runway, females2.42.73.61.2-1.61.2-1.8-1.7-1.8-1.9-1.91.9-1.1
Run reversals in cocaine runway, males2.62.94.11.4-1.71.2-1.8-1.7-1.9-2.0-2.02.0-1.2
Latency to leave start box in cocaine runway0.30.41.9-1.00.7-0.80.40.1-0.4-0.0-0.10.1-1.4
Latency to leave start box in cocaine runway, F0.60.83.4-1.20.8-1.20.30.2-0.4-0.2-0.20.2-1.8
Latency to leave start box in cocaine runway, M0.10.10.30.10.00.30.2-0.00.10.30.3-0.40.5
Std. dev. time between licks in bursts0.81.52.10.8-1.00.7-1.2-1.3-1.5-1.4-1.41.4-1.2
Total sessions with >9 infusions0.00.10.20.1-0.20.2-0.0-0.3-0.30.4-0.20.0-0.3
Short access day 1 total inactive lever presses0.30.61.41.1-1.01.2-0.8-0.8-0.6-0.4-0.40.50.5
Short access day 10 total inactive lever presses0.10.62.51.2-0.81.2-0.3-0.30.20.10.2-0.21.6
Short access day 1 total infusions0.00.10.10.2-0.20.3-0.1-0.3-0.30.3-0.20.1-0.3
Short access day 10 total infusions0.00.00.10.1-0.10.10.1-0.0-0.00.30.0-0.10.2
Short access total infusions0.10.10.4-0.20.1-0.20.30.00.00.60.1-0.2-0.4
Short access day 1 locomotion0.81.42.51.5-1.51.6-1.1-1.3-1.2-0.5-1.11.00.4
Short access day 10 total locomotion0.93.88.22.9-2.42.8-1.9-1.9-1.5-0.8-1.31.31.3
Short access total locomotion0.81.12.41.5-1.41.5-1.0-1.1-1.0-0.2-0.90.80.5
One hour access (0.3 mA shock)0.10.10.30.00.10.00.30.30.50.50.4-0.50.4
Compulsive drug intake0.00.00.1-0.0-0.0-0.00.0-0.0-0.2-0.2-0.20.0-0.4
One hour access (shock baseline)0.10.20.50.7-0.60.7-0.5-0.5-0.2-0.0-0.30.30.3
Social response proportion0.60.71.10.7-0.80.5-1.0-0.8-0.8-1.0-1.01.1-0.6
Social responses7.910.312.63.0-3.33.0-3.5-3.4-3.5-3.4-3.53.6-1.4
Social time1.11.82.5-1.11.4-1.31.41.51.61.31.4-1.40.7
Soleus weight6.017.521.6-4.54.6-4.54.54.44.34.24.3-4.20.7
Bone: stiffness2.64.78.1-2.82.5-2.82.32.21.91.91.8-1.8-0.7
Tibialis anterior weight1.34.65.8-2.42.4-2.42.32.32.32.12.2-2.10.4
Time to tail flick, vehicle, before self-admin1.41.82.51.1-1.21.0-1.5-1.4-1.4-1.4-1.51.6-1.2
Time to tail flick, vehicle, after self-admin0.20.31.70.7-0.50.9-0.2-0.20.1-0.30.3-0.21.3
Time to tail flick, test, before self-admin1.01.21.90.5-0.80.5-1.0-1.1-1.4-1.3-1.21.2-1.3
Time to tail flick, test, after self-admin0.10.10.4-0.1-0.00.0-0.1-0.2-0.4-0.2-0.20.2-0.6
Delta time to tail flick, vehicle, before/after SA2.42.63.8-1.11.4-1.01.61.71.81.51.9-1.91.7
Delta time to tail flick, test, before/after SA0.30.41.50.20.10.20.40.40.70.60.7-0.71.2
Tibia length0.61.52.51.6-1.51.5-1.3-1.4-1.2-1.1-1.21.00.2
Ambulatory time before self-admin0.20.50.70.8-0.80.7-0.8-0.8-0.6-0.6-0.60.6-0.1
Ambulatory time after self-admin0.00.00.1-0.20.2-0.20.20.20.10.30.1-0.1-0.1
Bone: tissue strength3.94.15.9-2.42.3-2.42.22.11.82.11.9-1.9-0.3
Total heroin consumption1.82.12.71.3-1.51.3-1.6-1.6-1.6-1.6-1.51.6-0.8
Bone: trabecular number0.50.93.0-0.1-0.50.2-0.5-0.9-1.3-1.1-1.01.0-1.7
Bone: trabecular spacing0.91.36.20.60.10.50.40.61.21.21.0-1.02.5
Bone: trabecular thickness1.41.911.4-1.40.5-1.2-0.0-0.3-1.1-1.1-0.90.9-3.4
Bone: trabecular tissue density3.66.37.7-2.32.6-2.32.72.72.72.72.8-2.71.2
Water consumed over 24 hours0.40.71.5-1.21.0-1.10.90.70.50.60.6-0.7-0.8
Number of responses in last shaping day2.93.86.82.6-2.42.6-2.0-2.2-1.7-1.3-1.71.60.5