Hub : Genes

Tmem184b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio NM_001173370.1 0.02 0.01 4.3e-03 0.01 0.02 0.02 0.02 1.1e-02 1.6e-03 2.5e-03 3.6e-03
2 BLA gene expression Tmem184b 0.33 0.12 4.8e-12 0.19 0.17 0.16 0.18 2.2e-10 1.1e-09 4.4e-09 5.9e-10
3 PL intron excision ratio chr7_110927263_110929756 0.05 0.03 1.4e-04 0.02 0.03 0.03 0.02 3.2e-03 2.1e-04 8.3e-04 1.0e-03
4 OFC gene expression Tmem184b 0.49 0.16 1.7e-06 0.13 0.2 0.26 0.3 4.7e-04 1.8e-05 6.5e-07 8.1e-08
5 pVTA gene expression Tmem184b 0.12 0.07 9.2e-05 0.07 0.11 0.06 0.09 3.6e-04 1.4e-05 1.7e-03 1.3e-04
6 Adipose mRNA stability Tmem184b 0.04 0.03 3.7e-05 0.03 0.04 0.02 0.02 3.5e-04 7.9e-05 1.4e-03 2.1e-03
7 NAcc gene expression Tmem184b 0.34 0.08 0.0e+00 0.35 0.36 0.37 0.38 3.3e-42 2.1e-43 2.5e-45 9.6e-47
8 PL gene expression Tmem184b 0.22 0.09 0.0e+00 0.22 0.18 0.21 0.21 1.0e-23 1.9e-19 2.5e-22 3.6e-23
9 Brain gene expression Tmem184b 0.64 0.11 0.0e+00 0.32 0.33 0.34 0.35 1.2e-30 2.1e-31 2.5e-32 5.3e-34
10 Adipose gene expression Tmem184b 0.48 0.12 0.0e+00 0.36 0.44 0.44 0.44 2.2e-41 2.3e-53 6.4e-53 1.4e-53
11 PL mRNA stability Tmem184b 0.05 0.03 4.9e-05 0.01 0.03 0.02 0.02 6.3e-02 1.1e-04 3.0e-03 2.7e-03
12 RMTg gene expression Tmem184b 0.16 0.1 4.4e-03 0.1 0.04 0.05 0.06 1.3e-03 3.6e-02 2.3e-02 1.4e-02
13 Brain mRNA stability Tmem184b 0.13 0.09 3.2e-05 0.06 0.05 0.06 0.07 2.5e-06 1.9e-05 7.4e-06 7.5e-07
14 OFC isoform ratio XM_017594986.2 0.16 0.09 8.1e-03 0.14 0.09 0.05 0.07 3.5e-04 4.9e-03 2.8e-02 8.7e-03
15 BLA mRNA stability Tmem184b 0.1 0.05 2.0e-04 0.09 0.07 0.07 0.08 1.7e-05 1.2e-04 1.3e-04 4.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.10.21.4-0.10.3-0.1-0.1-0.00.1-0.10.1-0.1-0.0-0.0-1.2-1.1-0.30.2
Area under the delay curve2.52.65.6-2.42.0-2.0-1.6-2.2-2.0-1.81.5-1.5-2.00.80.20.21.3-0.6
BMI with tail0.20.51.90.20.20.3-0.4-0.6-0.1-0.50.3-0.2-0.41.01.41.40.7-1.2
BMI without tail0.61.32.2-0.81.4-0.4-1.5-1.2-1.1-1.51.5-1.4-1.20.21.01.00.6-1.1
Body weight0.83.27.22.7-2.42.02.12.22.42.0-2.12.11.90.3-0.0-0.0-0.3-0.1
Weight adjusted by age1.01.13.01.6-1.01.71.31.21.01.2-1.21.21.10.30.10.1-0.5-0.4
Bone surface0.10.20.9-0.20.3-0.1-0.2-0.4-0.4-0.40.2-0.3-0.50.6-0.6-0.60.5-1.0
Bone volume0.10.21.4-0.20.4-0.1-0.3-0.2-0.3-0.40.4-0.4-0.4-0.0-1.2-1.1-0.1-0.2
Breakpoint value in progressive ratio session0.70.81.6-1.01.2-1.1-1.2-0.9-0.7-1.21.3-1.2-1.0-0.30.10.10.3-0.1
Number of licking bursts0.70.81.8-0.91.2-0.7-1.2-0.6-0.9-1.11.3-1.3-0.9-0.80.1-0.0-0.8-0.2
Context. condit. distance diff. score3.34.08.12.8-2.32.92.32.11.92.3-2.22.32.1-0.1-1.3-1.0-0.51.4
Locomotion velocity, session 10.80.82.10.3-1.10.31.30.40.21.1-1.51.20.41.21.00.70.9-0.7
Locomotion distance, session 12.53.26.5-2.32.0-1.6-1.7-2.2-2.5-2.01.6-1.9-2.40.80.70.71.6-1.6
Locomotion velocity, session 21.21.54.7-0.0-0.20.40.2-0.9-0.7-0.2-0.30.1-0.72.01.81.82.2-2.1
Locomotion distance, session 22.94.08.8-3.01.9-2.7-1.8-2.4-2.5-2.11.7-2.0-2.50.80.90.81.8-1.5
Locomotion velocity, session 31.01.14.91.7-1.02.21.21.00.31.2-1.21.10.80.0-0.6-0.7-0.50.4
Locomotion distance, session 30.91.02.3-0.51.50.3-1.3-0.7-1.4-1.01.3-1.3-1.1-1.1-0.5-0.6-0.90.5
Stereotopy head waving bouts, day 30.80.92.00.9-1.40.31.40.91.21.2-1.41.31.10.60.30.50.1-0.2
Stereotopy head waving duration, day 33.54.27.82.4-2.81.72.82.02.42.5-2.82.72.31.30.70.9-0.0-0.6
Locomotion velocity, session 70.50.61.31.1-0.60.90.71.11.00.8-0.60.60.8-0.3-0.7-0.5-0.80.0
Locomotion distance, session 70.81.02.00.2-0.7-0.50.91.21.11.1-0.80.91.0-0.9-1.4-1.2-1.11.2
Stereotopy head waving bouts, day 73.84.310.53.0-2.43.22.61.61.72.1-2.52.41.81.81.21.10.7-1.1
Stereotopy head waving duration, day 72.63.210.92.7-1.83.32.01.11.11.6-2.01.91.31.81.21.00.7-1.1
Locomotion velocity, session 81.92.34.61.6-2.11.52.11.11.01.8-2.21.91.11.51.21.10.8-0.6
Locomotion distance, session 80.40.61.60.9-0.91.31.00.30.30.9-1.11.00.50.8-0.3-0.20.70.1
Degree of sensitization distance3.94.08.21.4-2.70.12.62.32.92.6-2.62.72.60.3-0.8-0.6-0.31.1
Degree of sensitization stereotypy2.83.110.42.5-1.73.21.90.90.81.4-1.91.71.02.01.61.51.1-1.4
Conditioned locomotion0.80.91.51.2-1.00.91.11.21.21.1-1.11.01.20.10.60.8-0.5-0.2
Cocaine response after cond. corrected0.30.41.90.2-0.4-0.00.3-0.00.20.1-0.50.3-0.11.20.60.80.9-1.4
Cocaine response after cond. not corrected0.30.41.7-0.0-0.1-0.1-0.1-0.4-0.1-0.3-0.0-0.1-0.41.10.70.81.0-1.3
Cocaine response before conditioning0.50.61.5-0.61.0-0.2-1.2-0.8-0.8-1.01.2-1.1-0.8-0.6-0.2-0.3-0.00.4
Saline control response0.40.51.41.0-0.61.20.60.60.40.6-0.50.50.6-0.3-0.9-0.8-0.20.9
Bone: connectivity density0.30.52.10.4-0.40.20.60.70.60.6-0.50.50.6-0.3-1.4-1.4-0.60.5
Bone: cortical apparent density0.40.62.70.30.70.6-0.60.4-0.1-0.20.6-0.60.1-1.7-0.7-0.7-1.31.0
Bone: cortical area0.20.21.20.2-0.2-0.2-0.10.10.4-0.10.0-0.1-0.10.41.00.90.2-1.1
Bone: cortical porosity0.80.92.60.5-1.00.10.70.10.60.3-0.70.70.31.41.61.61.0-1.2
Bone: cortical porosity1.41.55.30.5-1.2-0.00.80.10.50.3-0.80.70.21.82.32.31.5-1.7
Bone: cortical thickness1.32.14.0-1.61.7-1.7-2.0-1.3-1.2-1.92.0-1.9-1.6-0.60.60.6-0.2-0.4
Bone: cortical thickness2.02.33.9-1.91.6-2.0-1.8-1.5-1.4-1.91.9-1.9-1.7-0.41.11.10.0-0.5
Bone: cortical tissue density0.40.62.70.30.60.7-0.50.5-0.0-0.00.5-0.50.2-1.6-0.8-0.7-1.31.0
Condit. Reinf. active minus inactive responses0.50.62.2-0.30.3-0.5-0.40.40.1-0.10.5-0.40.1-1.5-1.1-1.2-1.01.3
Condit. Reinf. active-inactive response ratio0.50.51.70.4-0.10.40.10.70.30.4-0.00.10.4-1.2-1.2-1.2-0.71.3
Condit. Reinf. active responses1.31.65.2-0.50.7-0.6-0.70.40.1-0.20.8-0.60.1-2.2-2.0-2.1-1.72.3
Condit. Reinf. inactive responses1.51.85.5-0.70.8-0.7-0.80.1-0.1-0.20.8-0.50.1-2.1-2.1-2.3-2.02.4
Incentive salience index mean0.81.04.2-0.30.5-0.7-0.60.70.4-0.00.6-0.50.3-2.1-1.0-1.3-1.71.5
Condit. Reinf. lever presses0.91.25.4-0.40.7-0.9-0.90.70.5-0.30.9-0.70.3-2.3-0.7-1.1-2.21.3
Condit. Reinf. active minus inactive responses0.30.41.6-1.00.1-1.3-0.2-0.7-0.5-0.30.1-0.2-0.60.60.30.30.8-0.1
Condit. Reinf. active-inactive response ratio0.10.10.6-0.4-0.4-0.80.3-0.10.10.2-0.40.4-0.10.60.10.30.6-0.1
Condit. Reinf. active responses0.40.52.0-0.8-0.1-0.90.1-0.8-0.6-0.3-0.10.0-0.71.20.50.61.4-0.6
Condit. Reinf. inactive responses0.30.40.8-0.60.4-0.4-0.3-0.7-0.9-0.60.4-0.6-0.80.60.70.80.8-0.8
Condit. Reinf. lever presses0.30.41.3-1.10.6-1.1-0.6-0.5-0.5-0.40.5-0.4-0.3-0.5-0.7-0.7-0.40.9
Condit. Reinf. lever reinforcers received0.20.31.4-0.6-0.4-0.80.3-0.6-0.3-0.0-0.30.3-0.31.10.30.51.2-0.4
Conditioned reinforcement - actives1.81.83.5-1.91.1-1.7-1.0-1.6-1.7-1.61.3-1.5-1.80.40.90.90.6-0.6
Conditioned reinforcement - inactives1.72.05.9-2.11.5-2.4-1.7-0.9-1.1-1.41.7-1.6-1.2-1.3-0.4-0.4-0.80.8
Conditioned locomotion0.91.12.7-1.40.2-1.6-0.6-1.2-1.0-1.20.7-0.8-1.41.00.90.90.9-0.9
Patch foraging indifference point 0 sec0.71.12.40.3-0.6-0.30.41.21.00.8-0.50.61.2-1.4-1.3-1.3-1.61.4
Patch foraging indifference point AUC1.21.43.8-1.91.2-2.0-1.5-1.0-1.3-1.31.3-1.4-1.4-0.60.10.1-0.3-0.0
Delay disc. indifference point, 0s delay0.20.20.9-0.60.2-1.0-0.3-0.6-0.1-0.60.4-0.3-0.40.40.30.30.7-0.3
Delay disc. indifference point, 16s delay2.92.95.7-2.42.0-2.0-1.5-2.2-2.0-1.91.6-1.7-2.10.81.11.11.3-1.0
Delay disc. indifference point, 2s delay7.38.114.9-3.22.8-2.4-2.7-3.9-3.3-3.22.5-2.6-3.62.12.12.13.1-2.2
Delay disc. indifference point, 24s delay0.10.10.4-0.20.2-0.30.00.4-0.10.2-0.1-0.10.0-0.50.50.5-0.6-0.3
Delay disc. indifference point, 4s delay1.31.43.1-1.71.1-1.4-0.8-1.8-1.4-1.10.7-0.7-1.41.30.60.61.5-0.7
Delay disc. indifference point, 8s delay1.61.74.1-2.01.7-1.9-1.4-1.2-1.3-1.21.3-1.3-1.2-0.7-1.1-1.1-0.10.5
Indifference point function ln k1.31.85.02.2-1.62.21.51.21.41.5-1.51.51.50.6-0.2-0.10.4-0.1
Indifference point function log k1.31.85.02.2-1.62.21.51.21.41.5-1.51.51.50.6-0.2-0.10.4-0.1
Patch foraging total patch changes 0 sec0.50.71.9-0.2-0.1-0.7-0.10.70.50.30.00.10.7-1.4-1.4-1.3-1.41.4
Patch foraging total patch changes 12 sec0.10.21.5-0.7-0.2-1.2-0.20.1-0.1-0.10.0-0.10.0-0.30.40.4-0.10.0
Patch foraging total patch changes 18 sec0.40.53.7-1.10.1-1.9-0.50.30.1-0.20.3-0.30.2-1.00.20.1-1.10.5
Patch foraging total patch changes 24 sec1.01.33.3-1.40.8-1.7-1.1-0.1-0.4-0.71.0-0.9-0.3-1.8-0.9-1.0-1.61.3
Patch foraging total patch changes 6 sec0.30.52.8-1.10.3-1.7-0.40.0-0.1-0.30.5-0.4-0.1-0.9-0.3-0.3-0.90.6
Patch foraging time to switch 0 sec0.81.24.8-0.1-0.30.00.6-0.8-0.10.0-0.50.5-0.22.21.81.91.7-1.6
Patch foraging water rate 0 sec2.03.27.60.9-0.70.10.42.21.71.2-0.50.71.6-2.6-2.6-2.7-2.82.4
Patch foraging water rate 12 sec0.40.62.50.60.20.5-0.60.80.5-0.10.6-0.50.6-1.6-1.2-1.2-1.10.6
Patch foraging water rate 18 sec1.01.44.30.9-0.60.40.71.81.31.0-0.50.51.4-1.9-0.8-0.9-2.11.1
Patch foraging water rate 24 sec2.13.05.22.2-1.81.71.72.32.11.9-1.61.62.2-0.9-1.4-1.6-0.91.1
Patch foraging water rate 6 sec1.21.76.70.60.40.3-0.71.20.70.20.5-0.40.6-2.6-1.7-2.0-2.31.7
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.10.50.4-0.1-0.6-0.6-0.40.2-0.2-0.60.90.20.20.3-0.4
Distance traveled before self-admin1.71.83.6-1.91.0-1.7-0.9-1.9-1.5-1.41.1-1.1-1.41.31.01.01.4-1.2
Distance traveled after self-admin0.40.41.4-0.2-0.7-1.20.80.80.80.7-0.70.70.8-0.20.30.3-0.40.0
Extensor digitorum longus weight0.72.74.9-1.62.2-1.0-2.0-2.2-1.7-2.22.0-1.9-2.00.81.11.00.8-1.0
Bone: elastic displacement0.91.01.71.2-1.11.01.31.01.11.2-1.31.31.10.60.50.5-0.6-0.2
Bone: elastic work1.92.44.01.5-1.90.92.01.11.61.5-2.01.91.31.81.51.51.0-1.2
Bone: endosteal estimation1.22.75.31.7-2.31.22.31.41.61.8-2.22.01.51.60.80.80.9-1.3
Bone: endosteal perimeter1.42.84.12.0-2.01.61.91.31.61.5-1.91.71.31.81.71.61.0-2.0
Epididymis fat weight0.61.54.32.1-1.72.01.41.21.21.2-1.21.20.90.30.20.20.8-0.2
Delta time in closed arm before/after self-admin0.20.20.7-0.70.2-0.8-0.4-0.5-0.5-0.60.5-0.5-0.60.00.20.20.2-0.1
Delta time in open arm before/after self-admin0.10.00.1-0.30.2-0.2-0.1-0.3-0.3-0.30.3-0.2-0.20.30.00.00.0-0.2
Diff in mean of infusions in LGA sessions0.40.40.9-0.70.6-0.9-0.5-0.0-0.3-0.40.6-0.6-0.4-1.0-1.0-1.0-0.60.5
Delay discount exponential model param2.52.75.62.4-2.01.91.72.22.11.8-1.51.62.1-0.7-0.1-0.1-1.20.6
Extinction: sum of active levers before priming2.92.84.6-1.81.8-1.3-1.6-2.1-1.9-2.01.7-1.8-2.11.01.31.31.4-1.7
Active lever presses in extinction session 60.10.10.3-0.10.0-0.2-0.0-0.10.0-0.10.0-0.1-0.10.30.50.50.4-0.5
Bone: final force0.40.72.30.2-0.6-0.40.60.20.50.2-0.50.40.21.21.41.21.1-1.5
Bone: final moment0.50.81.90.4-0.9-0.30.90.40.80.5-0.80.70.51.21.21.11.0-1.4
Food consumed during 24 hour testing period0.20.20.9-0.2-0.2-0.6-0.2-0.2-0.1-0.50.2-0.3-0.40.50.80.60.5-1.0
Glucose0.40.71.70.3-0.3-0.5-0.00.91.00.4-0.00.20.8-1.2-1.2-1.1-1.31.0
Heart weight2.33.26.42.0-1.81.11.52.52.41.8-1.41.52.2-1.6-1.7-1.7-1.71.5
Delay discount hyperbolic model param3.13.36.52.5-2.22.11.82.52.32.0-1.61.72.3-1.0-0.4-0.4-1.60.8
Intermittent access intake day 1-15 change0.60.61.7-0.71.0-0.7-1.3-0.4-0.6-0.81.0-1.0-0.6-1.0-0.1-0.2-0.50.5
Intermittent access intake escalation1.01.02.9-1.01.3-0.9-1.7-0.7-0.9-1.21.4-1.3-1.0-1.0-0.1-0.2-0.30.3
Intermittent access intake escalation 20.60.61.5-0.70.8-0.8-1.1-0.2-0.4-0.71.0-0.9-0.5-1.2-0.4-0.5-0.70.7
Intermitt. access day 1 inactive lever presses0.60.61.30.3-1.0-0.41.11.01.11.1-1.01.11.1-0.10.00.1-0.40.4
Intermitt. access day 15 inactive lever presses0.10.20.6-0.2-0.5-0.80.30.50.50.4-0.30.30.4-0.50.10.1-0.40.4
Intermitt. access escalation Index0.70.61.1-0.71.0-0.3-1.0-0.9-0.9-0.90.9-0.9-0.80.10.90.90.4-0.4
Intermittent access day 1 total infusions0.91.02.1-1.1-0.1-1.2-0.0-1.1-1.0-0.70.2-0.4-1.01.41.21.31.3-1.3
Intermittent access day 15 total infusions0.80.92.5-1.40.6-1.6-1.0-1.0-1.1-1.10.9-1.0-1.10.20.60.70.6-0.6
Intermittent access terminal intake (last 3 days)0.60.61.2-1.10.5-1.0-0.7-0.9-1.0-0.90.7-0.8-0.90.40.80.80.5-0.5
Intermittent access total infusions1.31.52.5-1.50.4-1.6-0.6-1.4-1.3-1.10.7-0.9-1.31.31.41.51.3-1.3
Intermittent access day 1 locomotion0.20.21.3-0.8-0.2-1.10.1-0.4-0.3-0.40.2-0.2-0.50.50.20.30.4-0.4
Intermittent access day 15 total locomotion0.20.20.9-0.70.1-0.9-0.6-0.2-0.4-0.50.6-0.6-0.4-0.5-0.2-0.3-0.20.2
Intermittent access total locomotion0.20.21.7-0.6-0.4-1.3-0.10.10.2-0.20.2-0.2-0.1-0.4-0.2-0.3-0.30.3
Intermittent access standard deviation0.50.52.8-1.1-0.1-1.7-0.4-0.4-0.3-0.70.6-0.6-0.60.10.80.70.4-0.4
Left kidney weight3.710.522.24.3-4.73.34.43.53.63.9-4.34.13.01.60.10.20.4-0.3
Right kidney weight4.713.228.84.4-5.42.64.84.54.54.5-4.64.54.00.2-0.4-0.4-0.61.0
Cocaine induced anxiety0.40.51.11.0-0.81.11.00.30.70.6-0.80.90.40.90.30.20.2-0.2
Post-drug Anxiety4.34.88.32.6-2.42.22.92.42.62.8-2.72.82.50.3-0.8-0.9-0.90.9
Baseline Anxiety1.92.04.00.9-0.60.50.81.61.41.4-0.91.01.6-1.7-2.0-2.0-1.71.7
Tail length0.41.33.50.8-0.60.30.41.41.00.8-0.40.41.1-1.8-1.7-1.9-1.41.4
Length with tail1.96.812.03.2-3.32.22.93.53.23.1-2.92.93.0-0.9-1.7-1.8-1.31.4
Length without tail3.06.512.43.0-3.52.13.33.02.93.2-3.23.22.70.1-1.4-1.4-0.71.2
Times rat made contact with spout1.82.07.8-0.71.0-1.1-1.30.6-0.1-0.71.4-1.4-0.1-2.8-1.9-2.0-2.11.2
Lifetime Intake1.31.53.0-1.50.2-1.7-0.5-1.3-1.1-1.00.6-0.7-1.21.31.41.51.4-1.4
Liver weight, left0.91.54.41.8-1.32.11.30.70.70.9-1.31.10.51.50.90.90.8-1.4
Liver weight, right1.72.89.52.8-1.83.12.01.61.41.8-1.91.81.50.6-0.4-0.40.10.1
Locomotor activity0.50.81.71.3-1.30.91.10.91.00.9-1.00.90.90.00.60.60.4-0.1
Locomotor testing distance0.30.51.4-0.40.7-0.4-1.2-0.4-0.6-0.91.2-1.1-0.6-1.1-0.1-0.1-0.20.4
Locomotor testing rearing0.10.20.90.4-0.50.40.10.10.0-0.0-0.0-0.00.00.20.70.71.0-0.5
Locomotion in novel chamber0.91.12.3-0.31.50.5-1.3-0.5-0.9-0.81.2-1.0-0.6-1.4-1.1-1.0-1.31.3
Locomotion in novel chamber post-restriction2.53.05.1-1.92.1-1.1-2.1-2.2-2.2-2.32.2-2.2-2.20.10.80.80.9-0.7
Fecal boli incidents, locomotor time 10.20.31.5-0.5-0.1-1.20.10.70.50.3-0.10.10.6-0.60.10.1-0.80.2
Change in fecal boli incidents, locomotor task0.20.21.20.9-0.21.10.10.50.10.2-0.1-0.0-0.0-0.50.30.3-0.4-0.1
Time >=10cm from walls, locomotor time 10.40.41.10.5-1.0-0.10.90.70.80.5-0.70.60.60.50.80.80.1-0.6
Bouts of movement, locomotor time 10.00.00.20.3-0.20.2-0.10.40.3-0.00.0-0.10.1-0.3-0.0-0.0-0.10.1
Total resting periods, locomotor time 10.10.10.20.2-0.2-0.10.00.50.50.1-0.10.10.3-0.10.30.3-0.2-0.0
Rest time, locomotor task time 10.50.61.40.2-0.5-0.60.71.11.10.9-0.70.71.1-0.70.00.0-1.20.7
Distance moved, locomotor task time 10.30.42.11.1-0.71.50.50.30.20.5-0.60.50.30.4-0.1-0.10.4-0.4
Vertical activity count, locomotor time 11.61.73.71.0-0.70.50.51.51.40.9-0.40.61.2-1.8-1.9-1.9-1.91.5
Time >=10cm from walls, locomotor time 21.21.33.61.2-0.90.50.91.91.71.2-1.00.91.5-0.70.60.6-1.6-0.0
Bouts of movement, locomotor time 22.62.85.0-1.41.7-0.8-2.0-2.1-1.9-2.22.0-2.0-2.10.81.31.31.5-1.0
Total resting periods, locomotor time 23.43.65.9-1.71.8-1.2-2.2-2.4-2.1-2.42.1-2.1-2.41.01.61.61.7-1.2
Rest time, locomotor task time 20.10.20.8-0.70.4-0.9-0.1-0.2-0.2-0.20.2-0.3-0.2-0.10.50.5-0.20.2
Distance moved, locomotor task time 20.91.12.51.6-1.11.50.91.31.21.1-1.11.11.1-0.1-0.8-0.8-0.5-0.0
Vertical activity count, locomotor time 21.41.63.61.3-0.90.50.71.91.71.1-0.70.81.5-1.5-1.4-1.4-1.60.8
Light reinforcement 10.10.10.40.1-0.20.3-0.0-0.1-0.1-0.1-0.0-0.10.00.50.60.60.3-0.6
Light reinforcement 20.30.41.20.6-0.21.00.1-0.4-0.3-0.40.1-0.2-0.31.00.91.00.7-1.1
Bone: marrow area1.32.95.81.8-2.41.22.41.51.61.8-2.32.11.61.70.90.80.9-1.3
Bone: maximum diameter1.32.44.41.8-2.11.11.81.41.71.5-1.81.71.31.51.41.30.7-1.7
Bone: maximum force0.50.92.70.2-0.9-0.40.80.30.70.3-0.70.60.21.41.61.40.9-1.6
Bone: maximum moment0.61.02.50.4-1.1-0.31.10.50.90.6-1.00.90.41.51.61.40.9-1.6
Mean time between licks in bursts0.81.13.0-0.30.60.3-0.4-1.2-0.8-0.70.3-0.3-0.81.71.41.41.5-1.7
Mean num. licks in bursts0.60.72.30.5-0.50.20.30.90.70.6-0.30.40.7-1.1-1.5-1.4-0.51.1
Cd content in liver0.91.02.50.20.40.9-0.6-1.0-0.9-0.90.7-0.7-1.00.91.61.61.3-0.8
Co content in liver0.40.51.3-0.30.6-0.2-0.8-0.6-0.4-0.80.8-0.8-0.70.21.11.10.3-0.6
Cu content in liver2.02.45.2-1.72.3-1.0-2.1-1.8-1.8-2.02.1-2.0-1.7-0.30.20.20.1-0.4
Fe content in liver2.63.15.32.3-2.31.92.11.82.01.9-2.12.01.90.81.51.5-0.4-0.4
K content in liver0.30.31.2-0.60.2-0.5-0.1-0.6-0.4-0.30.1-0.1-0.40.90.40.41.1-0.9
Mg content in liver0.10.10.5-0.40.0-0.50.0-0.3-0.2-0.1-0.10.1-0.10.70.20.20.6-0.7
Mn content in liver0.80.92.0-0.91.2-0.4-1.1-1.3-1.3-1.21.2-1.1-1.40.10.30.30.5-0.1
Na content in liver0.10.10.4-0.10.2-0.1-0.1-0.0-0.0-0.20.3-0.30.1-0.3-0.6-0.60.0-0.0
Rb content in liver0.10.10.8-0.2-0.1-0.50.20.30.30.2-0.10.10.2-0.4-0.4-0.4-0.90.2
Se content in liver1.21.42.8-0.31.50.7-1.7-1.3-1.5-1.61.6-1.6-1.50.00.70.70.6-0.6
Sr content in liver2.92.65.1-1.82.3-1.1-2.2-1.9-1.8-2.02.2-2.0-1.8-0.7-0.9-0.9-0.10.6
Zn content in liver0.50.61.1-0.61.0-0.1-0.9-0.9-1.0-1.00.8-0.9-1.00.40.10.10.8-0.8
Bone: minimum diameter0.10.20.50.2-0.7-0.20.50.20.40.3-0.50.40.10.70.60.60.5-0.7
Time in familiar zone, hab. session 10.10.10.90.1-0.0-0.00.20.20.2-0.0-0.1-0.00.00.40.20.4-0.1-0.9
Time in novel zone, hab. session 10.30.30.80.9-0.80.90.50.40.40.5-0.60.60.50.30.60.50.30.0
Total zone transitions, hab. session 11.31.94.1-1.31.9-0.3-1.7-1.6-2.0-1.71.7-1.8-1.9-0.4-0.7-0.50.10.0
Total locomotion distance, hab. session 10.60.81.5-0.41.00.3-1.1-0.7-1.2-1.01.1-1.2-1.1-0.7-1.1-0.9-0.10.3
Locomotion velocity, hab. session 10.81.12.0-0.81.2-0.2-1.3-0.8-1.3-1.11.3-1.3-1.2-0.8-1.4-1.2-0.20.4
Time in familiar zone, hab. session 20.30.30.60.30.70.8-0.6-0.0-0.3-0.60.7-0.7-0.4-0.5-0.6-0.4-0.8-0.1
Time in novel zone, hab. session 20.20.21.5-0.8-0.3-1.20.1-0.3-0.10.0-0.10.2-0.10.10.20.00.70.4
Total zone transitions, hab. session 20.50.62.1-1.40.8-1.5-0.7-0.5-0.9-0.60.6-0.8-0.7-0.50.30.4-0.5-0.2
Total locomotion distance, hab. session 20.40.51.5-1.10.4-1.2-0.5-0.7-0.7-0.60.4-0.6-0.80.30.90.80.2-0.7
Locomotion velocity, hab. session 20.30.51.8-1.20.5-1.4-0.5-0.5-0.6-0.50.5-0.6-0.60.10.70.7-0.1-0.5
Novel to familiar place preference ratio0.90.93.41.6-1.31.91.00.80.60.9-1.00.90.60.40.40.40.40.3
Novelty place preference1.01.04.31.8-1.32.11.10.90.70.9-1.00.90.60.20.30.40.30.3
Time in novel zone, NPP test1.11.14.71.9-1.42.21.11.00.71.0-1.01.00.70.10.20.20.20.5
Total zone transitions, NPP test1.11.53.4-1.61.7-0.9-1.4-1.3-1.8-1.31.4-1.5-1.6-0.50.00.0-0.2-0.1
Total locomotion distance, NPP test0.10.20.5-0.70.3-0.5-0.2-0.5-0.7-0.20.1-0.3-0.60.10.20.10.2-0.1
Locomotion velocity, NPP test0.30.51.1-1.10.8-0.7-0.7-0.8-1.1-0.70.6-0.7-0.90.10.20.20.1-0.3
Intraocular pressure0.30.40.60.6-0.80.50.60.30.30.5-0.80.60.30.80.70.70.7-0.5
Delta distance traveled before/after self-admin3.33.58.12.0-2.01.02.02.82.42.3-2.01.92.3-1.4-1.0-1.0-1.81.2
Delta ambulatory time before/after self-admin3.23.57.82.0-2.10.92.22.82.42.4-2.22.02.3-1.0-0.6-0.6-1.40.8
Parametrial fat weight0.71.44.60.8-0.10.4-0.21.41.20.8-0.20.31.2-2.1-1.4-1.4-2.01.7
Pavlov. Cond. lever latency0.10.10.30.3-0.50.20.50.10.10.4-0.60.50.20.5-0.30.00.3-0.1
Pavlov. Cond. magazine entry latency1.72.23.8-1.61.4-1.6-1.6-1.5-1.2-1.71.6-1.6-1.50.52.01.80.7-1.3
Pavlov. Cond. change in total contacts1.92.03.9-1.91.5-2.0-1.7-1.4-1.4-1.71.7-1.7-1.60.11.00.80.6-0.9
Pavlov. Cond. index score0.30.41.1-0.80.6-1.1-0.7-0.4-0.3-0.70.7-0.7-0.5-0.11.00.60.2-0.6
Pavlov. Cond. latency score0.20.20.5-0.60.4-0.7-0.5-0.3-0.2-0.50.5-0.5-0.3-0.00.70.40.1-0.4
Pavlov. Cond. lever contacts0.20.20.7-0.70.6-0.8-0.6-0.2-0.1-0.50.7-0.6-0.2-0.50.2-0.1-0.4-0.0
Pavlov. Cond. magazine entry number1.01.21.81.3-1.21.31.31.11.01.3-1.31.31.2-0.1-1.2-1.0-0.40.9
Pavlov. Cond. intertrial magazine entries1.01.34.0-0.1-0.1-0.40.20.90.60.6-0.20.20.6-1.8-2.0-2.0-1.41.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.2-1.00.8-1.1-1.0-0.6-0.5-0.91.0-1.0-0.7-0.20.80.50.1-0.6
Pavlov. Cond. response bias0.81.02.2-1.31.1-1.5-1.2-0.7-0.6-1.11.2-1.1-0.9-0.21.20.90.0-0.6
Pavlov. Cond. lever latency0.50.61.3-0.40.7-0.0-0.7-0.8-1.0-0.90.7-0.9-1.10.30.80.81.0-0.9
Pavlov. Cond. magazine entry latency0.50.62.9-1.40.6-1.7-0.6-0.5-0.3-0.60.7-0.6-0.3-0.6-0.5-0.4-0.50.8
Pavlov. Cond. change in total contacts1.72.35.01.0-1.9-0.22.01.82.22.0-2.02.12.10.40.30.3-0.80.3
Pavlov. Cond. index score0.30.41.3-0.4-0.2-0.90.30.50.60.5-0.20.40.7-0.6-0.6-0.5-1.01.1
Pavlov. Cond. latency score0.50.61.8-0.5-0.2-1.10.30.60.70.5-0.20.40.8-0.8-0.8-0.7-1.31.3
Pavlov. Cond. lever contacts0.50.61.60.3-0.5-0.00.50.80.90.8-0.50.71.1-0.6-0.9-0.8-1.31.1
Pavlov. Cond. magazine entry number0.30.31.50.40.20.8-0.3-0.3-0.5-0.40.2-0.4-0.60.60.60.50.9-1.2
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.2-0.1-0.8-0.10.40.30.2-0.0-0.00.1-0.8-0.4-0.5-0.60.5
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-0.3-0.2-0.70.30.40.60.4-0.20.40.6-0.4-0.6-0.5-0.91.0
Pavlov. Cond. response bias0.20.20.6-0.2-0.4-0.60.40.40.60.5-0.40.50.7-0.1-0.3-0.1-0.70.5
Time in closed arm before self-admin0.40.51.9-1.20.7-1.4-0.9-0.7-0.3-0.80.9-0.7-0.3-0.30.10.1-0.20.2
Time in closed arm after self-admin0.40.41.00.2-0.7-0.50.40.80.90.5-0.30.40.7-0.9-0.5-0.5-1.00.9
Time in open arm before self-admin0.80.81.41.0-0.51.00.91.10.71.1-0.90.81.0-0.7-1.2-1.2-0.70.7
Time in open arm after self-admin0.20.31.00.10.70.5-0.4-0.1-0.3-0.30.5-0.4-0.1-0.5-1.0-1.0-0.50.4
Bone: periosteal estimation0.71.52.51.2-1.60.71.50.91.21.1-1.41.30.91.51.31.20.8-1.6
Bone: periosteal perimeter1.52.53.81.9-1.91.21.71.51.71.4-1.71.61.31.31.81.70.5-1.8
Bone: post-yield work0.40.52.3-0.60.3-0.8-0.3-0.4-0.3-0.50.3-0.4-0.60.71.21.20.2-1.5
Progressive ratio test 1 active lever presses0.80.92.9-1.50.5-1.7-0.5-1.0-1.0-0.90.6-0.7-1.00.60.80.90.6-0.6
Progressive ratio test 1 breakpoint0.40.41.7-1.10.3-1.3-0.3-0.7-0.7-0.60.4-0.5-0.60.30.70.70.3-0.3
Progressive ratio test 1 inactive lever presses1.11.23.4-1.70.7-1.8-0.7-1.4-1.0-1.10.8-0.8-1.10.91.21.30.6-0.6
Progressive ratio test 2 active lever presses1.21.34.1-1.81.1-2.0-1.3-0.9-1.2-1.21.3-1.4-1.2-0.8-0.1-0.1-0.30.3
Progressive ratio test 2 breakpoint0.80.83.5-1.60.8-1.9-1.0-0.7-0.9-0.90.9-1.0-0.9-0.40.20.3-0.10.1
Progressive ratio test 2 inactive lever presses1.82.05.2-2.31.6-2.2-1.6-1.5-1.6-1.61.6-1.6-1.5-0.30.50.50.0-0.0
Incentive Sensitization - Responses0.60.61.5-0.70.9-0.7-1.1-0.2-0.5-0.60.9-0.9-0.5-1.2-0.6-0.6-0.80.8
Incentive Sensitization - Breakpoint0.60.61.5-0.80.9-0.8-1.0-0.2-0.6-0.60.9-0.9-0.5-1.2-0.6-0.7-0.80.8
Sum of active levers in priming session hrs 5-60.10.10.3-0.30.3-0.30.0-0.4-0.1-0.30.2-0.1-0.30.50.30.20.3-0.3
Progressive ratio0.20.20.7-0.3-0.5-0.40.6-0.10.10.4-0.50.60.10.5-0.8-0.80.20.2
Food seeking constrained by brief footshock0.60.71.7-0.40.3-0.2-0.7-0.8-0.7-0.90.7-0.9-1.00.71.11.11.0-1.3
Seeking ratio, punishment vs. effort0.50.62.1-0.30.6-0.2-0.8-0.4-0.4-0.80.8-0.9-0.6-0.11.41.40.3-0.9
Retroperitoneal fat weight2.06.514.53.8-3.33.13.03.03.23.0-2.92.82.80.1-0.00.0-0.40.3
Reaction time number correct0.70.92.2-0.41.40.5-1.2-0.9-1.5-1.31.3-1.4-1.3-0.30.20.10.0-0.5
Reaction time mean minus median0.00.10.20.2-0.40.10.50.10.20.3-0.30.40.20.3-0.1-0.1-0.10.2
Reaction time mean minus median AUC0.20.20.40.5-0.60.30.60.40.50.5-0.50.50.5-0.0-0.4-0.3-0.10.6
Reaction time num false alarms0.00.10.20.1-0.00.1-0.3-0.0-0.1-0.40.5-0.4-0.1-0.40.20.10.00.1
Reaction time num false alarms AUC0.10.10.20.00.10.1-0.3-0.2-0.3-0.40.5-0.5-0.2-0.30.30.10.30.1
Reaction time trials correct on left0.70.92.2-0.41.40.5-1.2-0.9-1.5-1.31.3-1.4-1.3-0.30.20.10.0-0.5
Reaction time trials on left0.81.12.6-0.51.50.4-1.3-1.1-1.6-1.41.4-1.5-1.4-0.30.20.10.1-0.6
Reaction time mean0.40.61.10.7-0.90.41.10.81.01.0-1.01.11.00.10.10.2-0.70.6
Reaction time mean AUC0.30.40.80.5-0.70.30.90.50.70.8-0.70.80.80.1-0.00.1-0.60.5
Median of all reaction times0.40.51.00.5-0.80.31.00.60.90.9-0.91.01.00.20.40.5-0.60.4
Reaction time omissions2.93.97.1-1.91.7-1.2-1.8-2.7-2.3-2.31.8-1.9-2.51.71.81.72.1-2.0
Reaction time false alarm rate0.00.10.20.2-0.4-0.10.10.20.30.1-0.00.10.3-0.20.10.00.20.4
Reaction time premature initiation rate0.20.20.6-0.0-0.7-0.80.40.40.70.3-0.40.40.40.00.30.60.1-0.3
Reaction time premature initiations0.00.00.3-0.2-0.1-0.5-0.00.10.1-0.10.1-0.2-0.1-0.30.10.2-0.1-0.2
Std. dev. reaction times0.30.40.90.7-1.00.40.90.70.80.8-0.80.80.8-0.0-0.2-0.2-0.40.5
Reaction time trials completed0.81.12.6-0.51.50.4-1.3-1.1-1.6-1.41.4-1.5-1.4-0.30.20.10.1-0.6
Reaction time trials AUC0.60.81.9-0.41.30.5-1.1-0.9-1.4-1.11.2-1.3-1.2-0.20.20.10.1-0.5
Run reversals in cocaine runway, females0.50.41.41.0-0.11.20.10.80.50.5-0.10.20.6-0.9-0.2-0.3-1.20.5
Run reversals in cocaine runway, males0.30.31.10.2-0.80.31.10.3-0.10.7-1.00.70.20.2-0.4-0.40.70.1
Latency to leave start box in cocaine runway1.41.54.81.0-0.91.51.0-0.30.10.7-1.21.10.22.21.51.61.7-1.3
Latency to leave start box in cocaine runway, F1.41.55.30.3-0.10.80.3-0.8-0.5-0.0-0.50.4-0.32.32.02.11.9-1.9
Latency to leave start box in cocaine runway, M0.60.61.41.0-1.01.20.80.10.20.7-0.90.90.21.10.50.50.6-0.2
Std. dev. time between licks in bursts0.20.30.70.2-0.6-0.10.70.40.50.7-0.80.80.60.3-0.1-0.00.30.1
Total sessions with >9 infusions0.10.11.0-0.5-0.4-1.00.2-0.1-0.1-0.1-0.10.0-0.20.30.30.40.3-0.3
Short access day 1 total inactive lever presses0.50.51.6-0.3-1.3-1.01.00.40.60.7-1.11.00.50.90.20.30.2-0.2
Short access day 10 total inactive lever presses2.72.96.11.5-1.70.51.72.52.22.0-1.61.62.2-1.7-1.2-1.2-1.71.7
Short access day 1 total infusions0.10.10.5-0.3-0.6-0.70.50.20.20.3-0.50.40.30.4-0.2-0.10.1-0.1
Short access day 10 total infusions1.11.23.5-1.0-0.4-1.20.1-0.9-0.7-0.60.1-0.3-0.81.51.71.91.5-1.5
Short access total infusions0.70.72.0-0.7-0.8-1.10.5-0.4-0.2-0.0-0.40.3-0.21.41.31.41.2-1.2
Short access day 1 locomotion0.30.31.8-1.0-0.1-1.3-0.2-0.6-0.5-0.40.2-0.2-0.50.60.30.40.4-0.4
Short access day 10 total locomotion1.01.15.2-1.50.6-2.3-1.0-0.3-0.1-0.91.2-0.9-0.3-1.2-1.0-0.9-0.90.9
Short access total locomotion0.30.32.7-0.7-0.6-1.70.20.20.40.0-0.10.20.1-0.1-0.10.0-0.30.3
One hour access (0.3 mA shock)4.55.28.9-3.02.5-2.5-2.6-2.7-2.8-2.82.6-2.7-2.60.31.31.31.1-1.1
Compulsive drug intake1.61.64.3-1.11.6-1.1-1.5-0.3-0.5-1.01.5-1.4-0.7-2.1-1.1-1.2-1.51.5
One hour access (shock baseline)1.21.42.2-1.30.7-1.0-1.0-1.5-1.4-1.31.0-1.1-1.31.01.31.41.2-1.2
Social response proportion2.22.38.60.2-0.40.40.4-1.1-0.3-0.3-0.40.4-0.52.92.52.62.3-2.5
Social responses0.91.13.4-0.80.4-0.7-0.5-1.2-0.9-0.80.4-0.5-0.81.21.81.81.3-1.3
Social time1.82.44.9-2.21.6-2.2-1.9-1.7-1.5-1.81.8-1.7-1.50.10.90.80.7-0.9
Soleus weight0.92.79.3-1.40.9-2.5-1.10.70.6-0.41.2-1.00.1-3.1-1.3-1.6-2.92.1
Bone: stiffness0.40.61.40.6-1.0-0.20.90.81.20.7-0.80.80.80.61.00.80.1-1.0
Tibialis anterior weight2.17.213.0-3.63.4-3.2-3.4-3.2-2.9-3.43.4-3.2-3.1-0.30.30.20.1-0.3
Time to tail flick, vehicle, before self-admin0.10.10.6-0.0-0.2-0.10.0-0.1-0.1-0.10.1-0.1-0.3-0.0-0.8-0.80.00.0
Time to tail flick, vehicle, after self-admin0.50.51.70.7-0.50.60.31.00.70.6-0.40.40.7-1.0-0.8-0.8-1.30.8
Time to tail flick, test, before self-admin1.31.22.3-1.31.2-0.9-1.2-1.4-1.5-1.41.3-1.3-1.50.10.60.50.6-0.4
Time to tail flick, test, after self-admin0.30.31.4-0.30.70.0-0.5-0.0-0.3-0.30.5-0.5-0.1-0.90.30.3-1.20.7
Delta time to tail flick, vehicle, before/after SA0.10.10.20.0-0.2-0.00.20.30.30.3-0.30.30.50.00.30.2-0.10.1
Delta time to tail flick, test, before/after SA0.50.42.30.30.50.6-0.50.40.20.10.3-0.20.4-1.2-0.5-0.5-1.51.0
Tibia length0.30.71.70.9-0.90.41.00.80.90.8-0.90.80.70.71.31.20.2-1.0
Ambulatory time before self-admin1.51.63.8-1.91.4-1.7-1.3-1.7-1.5-1.51.4-1.3-1.40.30.30.30.5-0.4
Ambulatory time after self-admin0.20.20.9-0.3-0.3-0.90.50.70.50.5-0.30.30.6-0.60.20.2-0.50.1
Bone: tissue strength0.20.20.30.5-0.50.40.40.40.50.4-0.40.50.30.30.40.40.0-0.1
Total heroin consumption1.51.73.2-1.31.2-0.9-1.3-1.6-1.5-1.71.4-1.5-1.80.60.80.81.4-1.2
Bone: trabecular number0.10.20.80.7-0.10.90.30.40.30.3-0.20.20.3-0.1-0.7-0.7-0.40.2
Bone: trabecular spacing0.50.63.2-0.1-0.4-0.90.20.50.60.1-0.20.10.20.01.81.8-0.5-1.0
Bone: trabecular thickness0.60.73.60.20.10.40.00.20.10.3-0.00.20.4-0.6-1.9-1.9-0.61.3
Bone: trabecular tissue density0.30.51.40.30.10.1-0.00.60.70.4-0.10.30.8-1.1-0.8-0.8-1.11.2
Water consumed over 24 hours0.30.41.5-0.30.2-0.6-0.50.3-0.1-0.40.6-0.7-0.2-1.2-1.0-1.1-0.80.6
Number of responses in last shaping day4.74.97.9-2.81.6-2.6-1.7-2.8-2.4-2.41.8-1.9-2.41.82.12.22.1-2.1