Hub : Genes

Tmem17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Tmem17 0.22 0.13 4.3e-03 -0.01 -0.01 -0 -0.01 6.5e-01 5.4e-01 3.8e-01 4.8e-01
2 NAcc isoform ratio XM_039092230.1 0.07 0.05 5.7e-05 0.04 0.04 0.04 0.04 7.2e-06 1.4e-05 7.5e-06 7.3e-06
3 BLA alternative TSS XM_017599320.2 0.06 0.05 6.4e-03 0.03 0.02 0.01 0.01 1.1e-02 2.3e-02 7.4e-02 4.8e-02
4 BLA isoform ratio XM_039092230.1 0.1 0.08 1.1e-03 0.07 0.06 0.04 0.06 1.8e-04 4.2e-04 4.3e-03 2.6e-04
5 PL isoform ratio XM_039092230.1 0.07 0.04 2.7e-06 0.05 0.05 0.04 0.05 1.8e-06 3.9e-06 4.9e-05 8.1e-06
6 Brain isoform ratio XM_039092230.1 0.1 0.07 8.2e-06 0.05 0.06 0.04 0.05 4.1e-05 3.3e-06 4.5e-05 3.2e-05
7 BLA intron excision ratio chr14_96522291_96523082 0.09 0.06 3.2e-03 0.03 0.03 0.03 0.02 1.2e-02 7.5e-03 9.8e-03 2.9e-02
8 Brain isoform ratio XM_017599320.2 0.28 0.14 7.4e-15 0.17 0.17 0.17 0.18 6.1e-16 1.3e-15 7.5e-16 1.9e-16
9 Brain gene expression Tmem17 0.03 0.02 6.9e-03 0.03 0.02 0.01 0.03 1.1e-03 8.0e-03 5.7e-02 1.6e-03
10 NAcc gene expression Tmem17 0.02 0.02 6.3e-03 0.02 0.02 0.01 0.01 3.5e-03 4.0e-03 9.3e-03 9.7e-03
11 Brain intron excision ratio chr14_96522291_96523082 0.06 0.04 2.3e-06 0.07 0.06 0.06 0.07 3.1e-07 2.9e-06 2.1e-06 9.1e-07
12 Liver gene expression Tmem17 0.03 0.02 5.8e-03 0.02 0.02 0.01 0.02 2.2e-03 3.2e-03 9.3e-03 4.2e-03
13 NAcc intron excision ratio chr14_96522291_96523082 0.06 0.04 6.1e-05 0.04 0.04 0.04 0.04 1.3e-05 3.0e-05 7.8e-06 7.3e-06
14 Liver isoform ratio XM_039092230.1 0.05 0.03 7.8e-06 0.04 0.04 0.04 0.04 2.0e-05 8.2e-06 1.3e-05 1.7e-05
15 BLA alternative TSS NM_001010961.2 0.17 0.11 1.7e-05 0.1 0.07 0.05 0.07 9.3e-06 8.4e-05 8.7e-04 9.0e-05
16 Brain alternative TSS NM_001010961.2 0.11 0.07 2.3e-09 0.11 0.1 0.1 0.1 9.9e-11 2.7e-09 1.3e-09 4.1e-09
17 Adipose gene expression Tmem17 0.16 0.08 0.0e+00 0.16 0.16 0.16 0.16 3.7e-17 8.2e-18 7.2e-17 1.4e-17
18 PL intron excision ratio chr14_96518946_96521938 0.04 0.03 2.2e-04 0.03 0.03 0.02 0.03 1.8e-04 2.6e-04 2.4e-03 5.1e-04
19 pVTA isoform ratio XM_017599321.2 0.06 0.05 7.0e-03 0.04 -0 -0 0.01 7.1e-03 5.4e-01 5.2e-01 9.5e-02
20 PL intron excision ratio chr14_96522291_96523082 0.12 0.06 4.1e-10 0.07 0.09 0.08 0.09 3.4e-08 2.3e-10 7.3e-09 8.0e-10
21 Brain alternative TSS XM_017599320.2 0.09 0.06 2.0e-08 0.08 0.08 0.08 0.07 6.4e-08 3.0e-08 5.4e-08 3.9e-07
22 Brain isoform ratio NM_001010961.2 0.08 0.06 8.1e-06 0.07 0.06 0.08 0.07 4.6e-07 3.1e-06 9.6e-08 3.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.50.91.8-1.0-1.31.3-1.0-1.11.1-1.2-1.0-1.2-1.30.5-0.5-0.81.2-0.4-0.41.2-0.20.1-0.9-1.0-0.2
Area under the delay curve3.94.16.42.22.4-2.42.52.4-1.71.52.42.11.9-2.42.52.3-1.62.52.5-1.40.4-0.61.81.61.9
BMI with tail0.72.15.42.31.6-1.61.51.7-1.91.61.41.61.5-1.21.31.4-1.01.51.5-1.0-1.81.70.40.50.5
BMI without tail2.14.37.12.72.6-2.62.42.5-2.31.82.42.31.8-2.22.42.2-1.42.22.2-1.5-1.01.01.41.41.7
Body weight2.410.219.54.43.6-3.63.43.6-3.83.53.43.53.2-3.63.53.4-2.83.53.5-2.7-1.71.81.92.11.8
Weight adjusted by age0.70.81.6-0.5-1.11.1-1.1-1.30.5-0.3-1.0-0.5-0.50.7-1.0-0.80.6-1.1-1.10.6-1.01.1-1.1-0.9-1.3
Bone surface0.40.71.5-0.1-0.80.8-0.7-0.80.6-0.9-0.6-1.1-1.20.3-0.3-0.71.2-0.2-0.21.2-1.21.1-1.2-1.2-0.5
Bone volume0.40.82.0-0.0-0.90.9-0.8-0.80.5-0.8-0.7-1.0-1.00.5-0.4-0.71.1-0.3-0.31.1-1.41.3-1.2-1.2-0.7
Breakpoint value in progressive ratio session1.01.13.01.70.9-0.91.11.0-1.51.40.91.31.5-0.50.61.0-0.90.60.6-0.9-1.61.50.20.4-0.3
Number of licking bursts0.10.20.40.30.2-0.20.30.3-0.50.40.40.30.3-0.60.60.5-0.40.60.6-0.4-0.20.20.20.30.5
Context. condit. distance diff. score0.40.41.0-1.0-0.70.7-0.7-0.80.9-0.9-0.7-0.5-0.50.6-0.5-0.50.7-0.7-0.70.70.6-0.5-0.4-0.5-0.2
Locomotion velocity, session 10.40.42.11.20.1-0.10.40.4-0.40.40.20.20.1-0.70.60.40.00.70.70.2-1.41.4-0.5-0.6-0.4
Locomotion distance, session 10.10.20.80.60.3-0.30.10.1-0.00.10.10.20.0-0.50.50.30.10.50.50.3-0.80.9-0.4-0.5-0.4
Locomotion velocity, session 20.20.20.5-0.7-0.40.4-0.7-0.70.7-0.4-0.6-0.6-0.7-0.20.1-0.20.40.30.30.5-0.1-0.0-0.6-0.6-0.2
Locomotion distance, session 21.21.73.8-0.3-1.11.1-1.3-1.31.1-1.2-1.2-1.3-1.50.6-0.7-1.11.6-0.6-0.61.7-1.71.7-1.9-1.9-1.5
Locomotion velocity, session 30.40.41.40.20.7-0.70.40.4-0.10.50.50.40.4-1.11.20.8-0.51.21.2-0.40.4-0.40.40.30.6
Locomotion distance, session 30.60.61.00.71.0-1.00.80.7-0.71.00.80.80.7-1.01.00.9-1.01.01.0-0.80.2-0.20.60.60.4
Stereotopy head waving bouts, day 30.50.61.1-0.5-0.90.9-0.8-0.70.7-0.8-0.9-0.8-0.70.7-0.7-0.70.9-0.6-0.61.0-0.80.7-1.0-1.0-0.8
Stereotopy head waving duration, day 30.10.10.3-0.3-0.40.4-0.2-0.20.4-0.4-0.4-0.2-0.10.5-0.4-0.30.3-0.4-0.40.30.1-0.1-0.2-0.2-0.3
Locomotion velocity, session 70.20.30.7-0.8-0.40.4-0.5-0.50.8-0.6-0.3-0.6-0.6-0.40.5-0.00.40.50.50.50.7-0.5-0.2-0.30.4
Locomotion distance, session 71.11.42.8-1.3-1.11.1-1.5-1.51.5-1.4-1.2-1.6-1.70.6-0.5-1.11.4-0.5-0.51.4-0.10.3-1.3-1.4-0.8
Stereotopy head waving bouts, day 70.60.71.20.40.8-0.80.90.9-0.80.80.81.01.1-0.60.50.8-1.00.60.6-1.00.7-0.81.11.10.9
Stereotopy head waving duration, day 71.51.83.11.51.5-1.51.61.6-1.61.71.41.71.8-1.01.01.4-1.61.01.0-1.6-0.1-0.11.31.40.8
Locomotion velocity, session 80.30.42.10.5-0.70.7-0.2-0.20.0-0.1-0.4-0.1-0.1-0.30.40.20.50.20.20.6-1.41.4-0.9-0.9-0.5
Locomotion distance, session 80.20.31.0-0.3-0.40.4-0.7-0.70.7-0.7-0.5-0.5-0.7-0.10.2-0.20.90.10.10.9-0.60.7-0.9-1.0-0.4
Degree of sensitization distance4.64.66.6-1.8-2.32.3-2.5-2.42.2-2.5-2.2-2.5-2.51.8-1.8-2.22.6-1.8-1.82.5-0.91.0-2.3-2.4-1.6
Degree of sensitization stereotypy2.83.04.41.32.0-2.01.91.9-1.81.91.82.12.1-1.41.41.7-2.11.31.3-2.10.9-1.02.02.11.5
Conditioned locomotion1.31.52.6-1.4-1.51.5-1.6-1.61.3-0.9-1.6-1.4-1.31.1-1.1-1.21.0-0.9-0.91.0-0.40.3-1.4-1.3-1.2
Cocaine response after cond. corrected1.01.15.10.5-0.80.8-0.6-0.60.1-0.1-0.8-0.4-0.40.7-0.7-0.60.8-0.8-0.80.9-2.32.2-1.5-1.4-1.7
Cocaine response after cond. not corrected0.40.43.00.6-0.30.3-0.3-0.3-0.20.2-0.3-0.2-0.10.1-0.1-0.10.4-0.2-0.20.4-1.71.7-1.0-0.8-1.0
Cocaine response before conditioning1.11.32.80.21.2-1.20.90.9-0.70.81.10.80.8-1.21.21.1-1.21.21.2-1.31.4-1.41.41.41.7
Saline control response1.52.03.0-1.6-1.51.5-1.4-1.41.7-1.3-1.7-1.4-1.41.5-1.5-1.51.2-1.5-1.51.30.2-0.2-1.2-1.4-1.7
Bone: connectivity density0.61.02.1-1.4-1.21.2-1.1-1.11.4-1.5-0.9-1.4-1.50.4-0.4-0.91.1-0.3-0.31.10.7-0.8-0.6-0.80.2
Bone: cortical apparent density1.01.35.3-0.20.9-0.91.01.0-0.30.70.81.41.4-0.40.40.9-1.30.40.4-1.32.3-2.11.71.50.9
Bone: cortical area1.82.74.12.01.9-1.91.91.9-1.81.61.81.71.7-1.81.81.8-1.51.71.7-1.4-0.30.31.31.31.3
Bone: cortical porosity0.00.00.20.10.0-0.00.10.1-0.10.20.0-0.1-0.1-0.30.30.1-0.10.40.4-0.0-0.20.1-0.1-0.10.1
Bone: cortical porosity0.00.00.20.40.1-0.10.20.2-0.20.30.00.0-0.0-0.10.10.0-0.20.20.2-0.1-0.50.3-0.1-0.1-0.2
Bone: cortical thickness1.72.73.61.31.7-1.71.71.7-1.61.71.61.91.8-1.91.91.9-1.71.81.8-1.70.5-0.61.61.61.6
Bone: cortical thickness0.10.10.5-0.1-0.30.3-0.2-0.20.1-0.0-0.4-0.1-0.10.7-0.7-0.40.1-0.5-0.50.1-0.30.2-0.3-0.2-0.6
Bone: cortical tissue density0.91.14.9-0.30.8-0.80.90.9-0.20.60.71.31.3-0.30.30.8-1.20.20.2-1.22.2-2.01.51.40.8
Condit. Reinf. active minus inactive responses0.91.02.10.41.2-1.21.21.2-0.60.71.01.11.1-0.50.30.7-1.00.40.4-1.01.5-1.41.41.30.8
Condit. Reinf. active-inactive response ratio0.50.61.10.60.9-0.91.01.0-0.70.60.81.01.0-0.10.00.5-0.7-0.1-0.1-0.80.7-0.71.10.90.4
Condit. Reinf. active responses0.70.91.50.61.2-1.21.11.1-0.70.91.01.11.1-0.70.50.8-1.10.60.6-1.01.0-0.91.21.10.6
Condit. Reinf. inactive responses0.40.50.90.80.9-0.90.60.6-0.80.90.70.70.6-0.80.70.7-0.80.90.9-0.7-0.40.40.30.40.3
Incentive salience index mean1.51.83.21.31.7-1.71.81.8-1.31.51.51.61.6-0.80.71.1-1.60.70.7-1.50.8-0.81.61.50.6
Condit. Reinf. lever presses1.01.43.21.81.6-1.61.61.6-1.31.51.31.31.2-0.80.71.0-1.30.80.8-1.1-0.40.40.80.8-0.0
Condit. Reinf. active minus inactive responses0.60.72.31.40.9-0.90.50.5-0.90.80.80.40.3-1.11.10.8-0.31.01.0-0.3-1.51.5-0.2-0.10.1
Condit. Reinf. active-inactive response ratio1.01.02.01.41.2-1.20.80.7-1.11.01.10.70.7-1.41.41.1-0.61.41.4-0.6-1.01.10.30.40.8
Condit. Reinf. active responses0.20.21.30.4-0.20.2-0.2-0.2-0.10.1-0.1-0.2-0.2-0.60.60.20.20.50.50.3-1.11.1-0.6-0.6-0.3
Condit. Reinf. inactive responses1.72.13.8-1.6-2.02.0-1.5-1.41.8-1.5-1.8-1.4-1.41.3-1.3-1.41.4-1.3-1.31.50.0-0.1-1.3-1.5-1.4
Condit. Reinf. lever presses0.20.20.6-0.20.4-0.40.20.20.00.20.30.40.3-0.80.80.6-0.40.70.7-0.40.8-0.70.50.40.6
Condit. Reinf. lever reinforcers received0.10.21.00.2-0.20.2-0.3-0.30.1-0.0-0.2-0.3-0.3-0.40.40.00.30.30.30.4-0.91.0-0.6-0.6-0.3
Conditioned reinforcement - actives0.30.31.71.00.2-0.20.30.5-0.80.70.30.10.2-0.10.10.2-0.30.30.3-0.3-1.31.2-0.2-0.0-0.2
Conditioned reinforcement - inactives1.41.62.91.20.8-0.81.31.5-1.61.71.11.41.4-1.20.81.1-1.71.21.2-1.70.2-0.31.31.51.1
Conditioned locomotion1.21.43.0-1.4-1.41.4-1.6-1.71.2-1.0-1.4-1.3-1.11.3-1.4-1.31.0-1.1-1.11.0-0.30.3-1.2-1.0-0.9
Patch foraging indifference point 0 sec0.10.20.9-0.5-0.50.5-0.7-0.90.4-0.4-0.3-0.6-0.3-0.30.1-0.10.50.40.40.5-0.10.2-0.5-0.50.3
Patch foraging indifference point AUC0.00.10.30.10.2-0.20.20.4-0.10.10.00.40.1-0.10.50.3-0.1-0.2-0.2-0.1-0.10.20.1-0.0-0.4
Delay disc. indifference point, 0s delay4.65.07.62.72.4-2.42.72.7-2.52.32.62.52.2-2.42.42.3-2.12.42.4-2.0-0.2-0.12.01.91.9
Delay disc. indifference point, 16s delay0.80.81.40.81.1-1.11.21.1-0.70.71.10.80.8-1.01.21.0-0.81.11.1-0.70.4-0.50.90.70.7
Delay disc. indifference point, 2s delay4.65.17.92.72.5-2.52.82.8-2.22.12.52.42.1-2.62.62.4-2.02.52.5-1.90.1-0.32.01.81.8
Delay disc. indifference point, 24s delay0.20.20.6-0.5-0.20.2-0.4-0.30.7-0.8-0.3-0.6-0.60.2-0.1-0.30.6-0.1-0.10.60.4-0.3-0.2-0.40.1
Delay disc. indifference point, 4s delay3.53.75.62.42.2-2.22.32.2-1.81.42.22.22.1-2.12.22.2-1.42.32.3-1.30.0-0.21.61.41.8
Delay disc. indifference point, 8s delay2.32.44.52.11.8-1.82.12.0-1.41.21.81.71.5-1.72.01.8-1.11.81.8-0.9-0.40.21.10.91.0
Indifference point function ln k0.10.10.30.40.2-0.2-0.1-0.10.0-0.30.3-0.4-0.0-0.40.10.10.40.60.60.4-0.60.5-0.3-0.40.4
Indifference point function log k0.10.10.30.40.2-0.2-0.1-0.10.0-0.30.3-0.4-0.0-0.40.10.10.40.60.60.4-0.60.5-0.3-0.40.4
Patch foraging total patch changes 0 sec0.20.31.0-0.5-0.50.5-0.8-1.00.6-0.6-0.4-0.7-0.4-0.1-0.1-0.20.70.20.20.7-0.30.4-0.7-0.70.1
Patch foraging total patch changes 12 sec0.30.41.3-0.2-0.60.6-0.7-0.70.2-0.3-0.5-0.8-0.70.20.1-0.30.6-0.3-0.30.5-0.91.2-0.9-0.7-0.5
Patch foraging total patch changes 18 sec2.02.64.5-2.1-2.02.0-1.8-1.81.9-2.0-1.9-1.2-1.21.6-1.5-1.41.7-1.8-1.81.70.4-0.2-1.3-1.4-1.1
Patch foraging total patch changes 24 sec0.10.20.6-0.30.3-0.3-0.1-0.10.3-0.30.1-0.1-0.2-0.70.70.30.20.80.80.20.3-0.10.0-0.10.6
Patch foraging total patch changes 6 sec0.20.30.5-0.7-0.40.4-0.6-0.70.7-0.7-0.5-0.6-0.7-0.20.1-0.20.7-0.2-0.20.7-0.10.3-0.6-0.7-0.1
Patch foraging time to switch 0 sec0.30.42.0-1.1-0.50.5-0.5-0.50.6-0.6-0.2-0.6-0.70.3-0.6-0.60.2-0.1-0.10.11.2-1.40.30.20.6
Patch foraging water rate 0 sec0.20.30.80.80.7-0.70.50.5-0.40.20.40.50.5-0.60.90.7-0.10.30.30.0-0.50.80.0-0.1-0.1
Patch foraging water rate 12 sec0.10.20.50.50.3-0.30.10.10.2-0.60.1-0.0-0.10.1-0.1-0.10.7-0.1-0.10.7-0.60.7-0.4-0.6-0.3
Patch foraging water rate 18 sec0.40.51.50.30.1-0.1-0.4-0.60.4-0.7-0.2-0.8-0.50.3-0.3-0.40.9-0.5-0.51.0-1.11.2-1.0-1.1-0.9
Patch foraging water rate 24 sec0.40.62.40.2-0.30.3-0.3-0.40.9-1.3-0.4-0.6-0.70.3-0.3-0.51.5-0.3-0.31.5-0.90.9-1.0-1.3-0.5
Patch foraging water rate 6 sec0.71.12.01.41.4-1.41.21.3-1.10.91.21.21.2-1.01.11.1-0.81.01.0-0.7-0.30.60.70.60.5
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.30.4-0.40.00.10.1-0.10.4-0.5-0.6-0.10.1-0.2-0.20.70.7-0.20.9-0.90.50.50.9
Distance traveled before self-admin0.91.02.21.40.8-0.80.81.3-1.21.10.81.51.3-0.70.71.0-0.71.11.1-0.7-1.21.20.30.30.3
Distance traveled after self-admin0.30.30.9-0.4-0.70.7-0.8-0.50.10.1-0.7-0.2-0.10.9-0.9-0.50.1-0.6-0.60.1-0.70.6-0.5-0.3-0.7
Extensor digitorum longus weight0.20.71.70.61.0-1.01.21.3-0.50.60.81.01.0-0.40.40.7-0.90.40.4-0.81.0-1.01.20.90.4
Bone: elastic displacement4.04.56.32.52.5-2.52.52.5-2.42.52.32.22.1-2.02.02.1-2.32.12.1-2.30.0-0.01.92.01.4
Bone: elastic work2.53.25.12.32.0-2.02.12.1-2.11.92.01.81.8-1.81.81.8-1.71.81.8-1.7-0.40.31.51.51.4
Bone: endosteal estimation0.30.74.51.60.7-0.70.50.5-0.70.20.6-0.1-0.1-0.30.30.10.40.30.30.4-2.12.0-0.6-0.6-0.3
Bone: endosteal perimeter0.30.52.41.61.1-1.10.80.8-0.90.50.80.30.3-0.20.20.3-0.10.10.1-0.1-1.41.2-0.0-0.0-0.1
Epididymis fat weight0.51.23.11.40.8-0.81.00.9-1.10.91.00.90.9-1.61.31.2-0.61.81.8-0.6-1.00.90.30.41.1
Delta time in closed arm before/after self-admin0.50.51.3-0.6-1.01.0-0.9-0.70.30.1-0.9-0.6-0.31.1-1.0-0.70.0-0.7-0.70.0-0.30.3-0.6-0.3-0.9
Delta time in open arm before/after self-admin0.40.40.90.10.9-0.90.80.70.3-0.60.70.30.1-0.60.60.40.20.30.30.20.9-1.00.70.30.8
Diff in mean of infusions in LGA sessions0.20.21.00.40.0-0.00.00.2-0.50.3-0.00.00.30.5-0.5-0.1-0.0-0.7-0.7-0.1-1.00.8-0.2-0.1-0.7
Delay discount exponential model param3.73.96.1-2.1-2.32.3-2.4-2.31.6-1.3-2.3-2.0-1.82.3-2.5-2.21.4-2.4-2.41.3-0.60.7-1.8-1.5-2.0
Extinction: sum of active levers before priming0.10.10.40.50.3-0.30.40.5-0.20.20.30.00.2-0.40.50.4-0.00.60.6-0.0-0.50.4-0.0-0.10.2
Active lever presses in extinction session 60.20.21.50.7-0.00.00.00.2-0.30.2-0.10.50.8-0.1-0.00.30.1-0.0-0.00.2-1.21.1-0.4-0.5-0.6
Bone: final force0.40.71.70.80.7-0.70.80.8-0.80.60.80.90.8-1.31.31.1-0.51.21.2-0.5-0.30.20.60.51.0
Bone: final moment0.61.02.11.20.9-0.91.11.1-1.10.91.01.11.0-1.41.41.3-0.71.31.3-0.7-0.50.30.60.61.0
Food consumed during 24 hour testing period0.60.71.71.11.3-1.31.11.1-0.70.61.00.80.8-0.80.80.8-0.60.90.9-0.50.1-0.00.70.60.5
Glucose0.20.30.5-0.3-0.50.5-0.6-0.60.4-0.5-0.5-0.7-0.70.5-0.4-0.50.7-0.4-0.40.6-0.70.6-0.7-0.7-0.4
Heart weight3.34.66.7-1.5-2.12.1-2.1-2.12.0-2.4-2.2-2.0-2.22.2-2.1-2.22.6-2.3-2.32.5-1.41.4-2.3-2.4-2.1
Delay discount hyperbolic model param4.44.77.2-2.4-2.62.6-2.7-2.61.8-1.5-2.6-2.2-2.02.5-2.7-2.41.6-2.7-2.71.4-0.40.5-2.0-1.6-2.1
Intermittent access intake day 1-15 change1.81.82.60.81.5-1.51.51.3-1.01.11.41.51.3-1.31.41.4-1.41.21.2-1.41.2-1.21.61.51.3
Intermittent access intake escalation2.82.73.91.62.0-2.02.01.7-1.51.51.82.01.8-1.91.91.9-1.71.31.3-1.60.6-0.71.71.71.2
Intermittent access intake escalation 21.91.92.71.11.6-1.61.71.3-1.11.21.51.51.2-1.61.61.5-1.41.31.3-1.30.9-0.91.51.41.3
Intermitt. access day 1 inactive lever presses0.20.20.60.30.2-0.20.50.2-0.70.60.40.20.5-0.40.20.3-0.70.30.3-0.80.2-0.40.60.80.6
Intermitt. access day 15 inactive lever presses0.80.91.91.40.9-0.91.31.1-1.30.91.11.11.1-0.60.70.9-0.80.90.9-0.9-0.40.40.90.91.0
Intermitt. access escalation Index3.32.94.5-2.0-2.12.1-2.0-1.71.6-1.6-1.9-1.9-1.92.0-2.1-2.01.6-1.6-1.61.5-0.30.3-1.5-1.4-1.1
Intermittent access day 1 total infusions2.02.34.8-0.2-1.61.6-1.2-1.00.4-0.5-1.5-1.4-1.22.0-1.8-1.51.1-1.7-1.71.0-2.22.1-1.8-1.5-2.1
Intermittent access day 15 total infusions0.30.31.21.10.5-0.50.80.7-0.80.80.40.50.5-0.00.20.3-0.5-0.1-0.1-0.5-0.90.80.10.2-0.5
Intermittent access terminal intake (last 3 days)0.10.10.30.40.2-0.20.50.3-0.30.40.1-0.0-0.10.2-0.0-0.1-0.3-0.4-0.4-0.3-0.30.10.10.1-0.5
Intermittent access total infusions0.50.51.40.0-0.70.7-0.3-0.30.1-0.1-0.7-0.7-0.61.2-1.0-0.80.3-1.0-1.00.3-0.90.8-0.7-0.5-1.1
Intermittent access day 1 locomotion2.82.94.2-1.0-1.71.7-1.5-1.61.4-1.5-1.7-2.0-2.02.0-1.9-2.01.8-1.5-1.51.8-1.41.3-1.9-1.9-1.7
Intermittent access day 15 total locomotion0.50.50.8-0.3-0.70.7-0.5-0.70.6-0.7-0.7-0.6-0.50.9-0.7-0.70.8-0.9-0.90.8-0.60.5-0.7-0.8-0.9
Intermittent access total locomotion2.32.64.1-1.3-1.81.8-1.6-1.71.6-1.6-1.7-1.8-1.62.0-1.9-1.81.6-1.6-1.61.6-0.70.5-1.6-1.6-1.6
Intermittent access standard deviation0.10.10.60.80.4-0.40.60.2-0.50.30.40.10.1-0.10.20.1-0.2-0.2-0.2-0.2-0.30.30.20.3-0.1
Left kidney weight2.15.910.83.33.1-3.13.03.0-2.72.72.72.92.9-2.22.42.6-2.32.02.0-2.2-0.70.91.81.80.9
Right kidney weight2.26.114.23.82.8-2.82.92.9-3.02.92.53.03.0-2.32.42.7-2.11.91.9-2.0-1.92.11.31.40.4
Cocaine induced anxiety0.20.21.2-0.8-0.20.2-0.3-0.30.3-0.1-0.2-0.1-0.10.4-0.3-0.2-0.20.00.0-0.21.0-1.10.30.30.5
Post-drug Anxiety0.60.71.7-0.10.6-0.60.60.6-0.50.60.70.80.7-0.40.50.6-0.91.01.0-1.01.1-1.21.01.01.3
Baseline Anxiety0.40.40.80.60.7-0.70.80.9-0.60.50.80.60.5-0.70.70.7-0.60.60.6-0.60.3-0.10.70.60.6
Tail length2.57.611.03.23.3-3.33.23.1-2.92.73.13.02.7-3.13.13.0-2.52.82.8-2.5-0.10.22.42.32.2
Length with tail2.710.015.23.63.6-3.63.43.4-3.33.43.53.23.1-3.93.73.5-3.23.53.5-3.00.10.02.72.72.4
Length without tail0.61.33.01.61.1-1.11.01.1-1.41.71.01.21.5-1.31.11.3-1.41.11.1-1.2-0.60.60.60.70.0
Times rat made contact with spout1.01.11.70.41.2-1.21.11.1-0.70.91.10.91.0-1.11.11.0-1.21.01.0-1.21.3-1.11.31.31.1
Lifetime Intake0.10.20.70.80.1-0.10.50.6-0.60.60.20.10.20.3-0.10.0-0.3-0.0-0.0-0.3-0.80.7-0.00.1-0.4
Liver weight, left0.40.62.2-0.10.8-0.80.70.7-0.10.20.70.80.5-0.80.70.7-0.60.80.8-0.61.5-1.41.10.81.0
Liver weight, right1.21.93.11.21.7-1.71.51.5-1.11.21.51.61.4-1.71.61.6-1.31.51.5-1.20.5-0.51.31.21.2
Locomotor activity1.42.23.5-1.3-1.91.9-1.5-1.21.6-1.8-1.7-1.4-1.51.3-1.6-1.61.8-1.2-1.21.8-0.50.7-1.5-1.7-1.2
Locomotor testing distance2.54.26.6-0.9-2.02.0-1.9-1.61.7-2.0-2.1-1.8-2.02.1-2.2-2.12.4-2.1-2.12.4-1.92.0-2.5-2.6-2.4
Locomotor testing rearing0.10.20.60.50.4-0.40.50.60.0-0.40.30.50.1-0.50.30.30.40.80.80.4-0.10.00.1-0.20.7
Locomotion in novel chamber1.31.63.0-0.6-1.21.2-1.3-1.10.7-0.6-1.2-1.0-0.81.7-1.5-1.21.0-1.1-1.11.0-1.71.7-1.6-1.4-1.7
Locomotion in novel chamber post-restriction0.10.10.50.4-0.00.00.10.1-0.10.3-0.10.30.10.3-0.3-0.1-0.00.10.10.1-0.60.7-0.4-0.3-0.5
Fecal boli incidents, locomotor time 11.61.83.61.01.5-1.51.41.6-1.31.31.41.81.9-1.31.41.7-1.31.21.2-1.30.4-0.31.31.31.1
Change in fecal boli incidents, locomotor task0.50.52.10.3-0.70.7-0.6-0.4-0.00.0-0.6-0.6-0.60.5-0.6-0.60.4-0.4-0.40.5-1.41.5-1.0-0.8-1.0
Time >=10cm from walls, locomotor time 11.01.03.5-0.6-0.70.7-0.7-0.81.3-1.5-0.8-1.3-1.90.6-0.6-1.21.4-0.8-0.81.5-0.00.0-0.9-1.2-0.7
Bouts of movement, locomotor time 10.10.10.30.60.1-0.10.30.1-0.40.10.30.30.4-0.2-0.00.2-0.10.50.5-0.1-0.20.40.30.20.6
Total resting periods, locomotor time 10.20.20.80.60.3-0.30.40.3-0.40.10.50.30.5-0.40.20.4-0.10.80.8-0.1-0.10.20.40.30.9
Rest time, locomotor task time 10.20.21.00.4-0.10.1-0.1-0.40.1-0.50.1-0.6-0.3-0.20.1-0.10.70.50.50.6-0.81.0-0.5-0.50.5
Distance moved, locomotor task time 10.10.10.6-0.30.2-0.20.00.00.20.2-0.1-0.1-0.3-0.10.0-0.2-0.3-0.3-0.3-0.20.7-0.80.20.2-0.3
Vertical activity count, locomotor time 10.80.81.4-1.2-0.80.8-1.0-0.91.1-0.9-1.0-0.9-1.20.9-0.9-1.10.7-1.1-1.10.80.5-0.6-0.6-0.7-1.0
Time >=10cm from walls, locomotor time 20.70.81.5-0.5-0.90.9-0.9-0.80.6-0.6-1.0-0.6-0.81.0-1.0-0.90.8-1.1-1.10.8-0.80.7-1.1-1.0-1.2
Bouts of movement, locomotor time 20.70.81.3-0.5-0.90.9-0.9-1.10.8-0.8-0.9-0.8-0.81.1-1.1-1.01.0-0.6-0.61.0-0.60.7-1.0-1.0-0.8
Total resting periods, locomotor time 21.01.12.0-0.9-1.31.3-1.2-1.41.2-1.2-1.2-1.1-1.01.2-1.3-1.11.2-0.5-0.51.2-0.30.4-1.1-1.1-0.6
Rest time, locomotor task time 20.80.91.8-0.7-1.01.0-0.9-1.21.1-1.3-0.9-1.2-0.90.9-1.0-0.91.3-0.4-0.41.3-0.40.4-1.0-1.1-0.2
Distance moved, locomotor task time 20.10.10.40.00.3-0.30.20.2-0.10.30.20.2-0.1-0.40.30.1-0.4-0.0-0.0-0.30.5-0.60.30.30.0
Vertical activity count, locomotor time 20.91.02.3-0.5-0.90.9-1.0-0.90.9-1.1-1.0-1.2-1.50.7-0.8-1.21.2-0.9-0.91.2-0.60.6-1.1-1.2-0.9
Light reinforcement 10.30.62.11.50.7-0.70.40.6-1.31.30.70.40.4-0.20.20.3-0.80.20.2-0.8-1.31.40.10.4-0.4
Light reinforcement 20.50.71.20.30.7-0.70.70.6-0.60.60.80.60.7-1.01.10.9-0.80.80.8-0.80.8-0.81.01.01.1
Bone: marrow area0.30.64.21.50.6-0.60.40.4-0.60.10.5-0.1-0.1-0.30.30.10.40.30.30.4-2.01.9-0.7-0.6-0.3
Bone: maximum diameter0.50.94.21.91.1-1.10.80.8-1.20.80.80.60.6-0.30.40.5-0.20.30.3-0.2-2.11.9-0.3-0.2-0.4
Bone: maximum force0.20.41.01.00.4-0.40.60.6-0.70.20.50.50.4-1.01.00.70.00.90.9-0.0-1.00.90.0-0.00.6
Bone: maximum moment0.40.72.01.40.7-0.70.90.9-1.00.60.80.70.6-1.11.20.9-0.21.01.0-0.2-1.21.10.10.10.6
Mean time between licks in bursts0.81.12.40.01.0-1.00.80.8-0.30.41.00.80.8-1.31.31.1-0.81.31.3-0.81.5-1.51.21.11.6
Mean num. licks in bursts0.10.10.5-0.00.4-0.40.30.30.00.10.20.10.10.2-0.2-0.1-0.3-0.2-0.2-0.20.7-0.60.40.3-0.1
Cd content in liver0.70.82.7-1.7-0.60.6-0.9-0.81.3-1.5-0.6-0.8-0.80.2-0.3-0.51.0-0.1-0.10.81.4-1.5-0.0-0.30.8
Co content in liver0.10.10.4-0.5-0.20.2-0.2-0.20.2-0.4-0.0-0.4-0.4-0.20.2-0.10.20.10.10.10.5-0.60.20.10.6
Cu content in liver0.91.02.70.40.7-0.70.80.8-0.60.70.90.70.7-1.71.61.2-0.91.61.6-0.80.7-0.70.90.81.4
Fe content in liver0.70.82.1-0.7-1.01.0-1.4-1.30.7-0.5-1.0-0.7-0.70.3-0.4-0.50.8-0.1-0.10.9-1.21.1-1.4-1.2-0.7
K content in liver0.60.61.41.20.9-0.91.01.0-0.91.10.70.50.5-0.70.70.6-0.90.60.6-0.8-0.50.30.50.5-0.0
Mg content in liver0.30.32.30.80.0-0.00.00.1-0.40.4-0.1-0.1-0.10.0-0.1-0.10.1-0.3-0.30.2-1.51.3-0.6-0.5-0.9
Mn content in liver0.70.81.61.21.2-1.21.21.1-0.80.81.00.50.4-1.31.20.9-0.71.21.2-0.6-0.20.10.60.50.7
Na content in liver0.10.10.50.50.3-0.30.2-0.0-0.10.20.0-0.1-0.2-0.00.0-0.10.0-0.0-0.00.1-0.70.6-0.3-0.3-0.6
Rb content in liver0.40.51.8-0.40.6-0.60.20.5-0.30.50.50.70.7-0.20.20.4-0.90.20.2-1.01.4-1.31.01.10.8
Se content in liver0.40.52.31.20.3-0.30.50.3-0.90.80.40.40.4-0.70.60.5-0.30.70.7-0.2-1.51.3-0.3-0.1-0.1
Sr content in liver0.40.41.1-0.4-0.30.3-0.3-0.50.8-1.1-0.3-1.0-1.00.3-0.3-0.61.0-0.2-0.21.0-0.0-0.1-0.5-0.70.0
Zn content in liver0.10.10.40.10.1-0.10.30.3-0.30.20.30.20.1-0.40.30.3-0.30.20.2-0.40.3-0.40.40.50.6
Bone: minimum diameter0.81.63.71.91.5-1.51.21.2-1.40.81.40.70.6-1.71.71.2-0.41.61.6-0.5-1.41.30.40.41.1
Time in familiar zone, hab. session 10.90.91.60.0-0.90.9-0.7-0.70.6-0.9-0.8-0.8-0.80.9-0.8-0.81.2-0.9-0.91.2-1.31.2-1.2-1.3-1.2
Time in novel zone, hab. session 10.10.10.4-0.6-0.20.2-0.3-0.30.3-0.4-0.2-0.3-0.30.2-0.3-0.30.2-0.2-0.20.10.6-0.50.10.10.3
Total zone transitions, hab. session 10.40.63.80.9-0.20.2-0.1-0.2-0.10.1-0.3-0.4-0.4-0.10.1-0.10.50.10.10.6-1.92.0-1.1-1.1-1.0
Total locomotion distance, hab. session 10.30.42.71.20.1-0.10.30.3-0.60.60.20.30.3-0.50.50.4-0.10.50.50.0-1.51.6-0.5-0.4-0.5
Locomotion velocity, hab. session 10.71.02.71.60.7-0.70.90.9-1.21.30.80.90.9-1.21.31.1-0.81.21.2-0.7-1.31.40.10.20.0
Time in familiar zone, hab. session 21.61.74.3-2.1-1.61.6-1.4-1.41.8-1.8-1.4-1.2-1.20.9-1.0-1.11.3-1.0-1.01.21.3-1.3-0.6-0.8-0.2
Time in novel zone, hab. session 21.01.03.11.81.1-1.11.01.0-1.51.31.00.90.9-0.60.60.8-0.80.70.7-0.8-1.41.30.30.50.1
Total zone transitions, hab. session 20.10.10.40.10.0-0.0-0.1-0.10.5-0.4-0.2-0.4-0.4-0.20.1-0.10.40.20.20.6-0.10.2-0.4-0.6-0.3
Total locomotion distance, hab. session 20.10.10.30.40.4-0.40.40.4-0.00.10.30.30.2-0.40.50.4-0.10.50.5-0.00.10.00.20.00.2
Locomotion velocity, hab. session 20.00.00.10.30.2-0.20.10.10.1-0.10.10.0-0.0-0.30.30.20.10.30.30.2-0.20.4-0.2-0.3-0.1
Novel to familiar place preference ratio0.30.30.8-0.9-0.70.7-0.4-0.40.5-0.6-0.5-0.6-0.50.7-0.7-0.70.3-0.7-0.70.20.8-0.70.00.0-0.0
Novelty place preference0.40.40.8-0.9-0.80.8-0.5-0.50.6-0.6-0.6-0.7-0.60.8-0.8-0.70.4-0.7-0.70.30.8-0.7-0.0-0.0-0.0
Time in novel zone, NPP test0.30.30.6-0.8-0.60.6-0.3-0.40.4-0.5-0.4-0.5-0.40.7-0.7-0.60.2-0.6-0.60.10.8-0.70.10.10.1
Total zone transitions, NPP test0.81.22.41.41.0-1.01.01.0-1.21.21.01.11.0-1.61.51.3-0.91.61.6-0.8-0.70.80.40.50.7
Total locomotion distance, NPP test0.70.91.71.10.7-0.70.90.9-1.01.00.91.01.0-1.31.21.1-0.91.31.3-0.8-0.20.30.60.70.8
Locomotion velocity, NPP test0.30.51.00.90.4-0.40.60.5-0.70.70.60.60.6-1.00.90.8-0.51.01.0-0.4-0.60.70.20.20.5
Intraocular pressure0.50.72.40.00.6-0.60.70.5-0.20.30.6-0.10.2-1.41.60.9-0.61.01.0-0.51.0-1.10.80.71.2
Delta distance traveled before/after self-admin0.50.61.5-1.2-0.80.8-0.8-1.00.6-0.4-0.7-1.0-0.90.9-0.8-0.90.2-1.0-1.00.10.7-0.8-0.2-0.0-0.3
Delta ambulatory time before/after self-admin1.82.03.6-1.4-1.61.6-1.6-1.71.1-1.0-1.5-1.7-1.61.9-1.8-1.70.9-1.8-1.80.9-0.20.1-1.1-0.9-1.4
Parametrial fat weight0.20.30.7-0.5-0.50.5-0.8-0.80.6-0.6-0.5-0.8-0.5-0.10.1-0.20.70.00.00.8-0.60.6-0.9-0.8-0.2
Pavlov. Cond. lever latency3.03.75.4-1.6-2.02.0-2.2-2.31.8-2.2-1.9-2.1-2.11.8-1.8-2.02.3-1.8-1.82.2-1.11.1-2.1-2.1-1.5
Pavlov. Cond. magazine entry latency0.50.72.01.41.1-1.10.90.9-1.00.90.90.50.5-0.90.80.7-0.60.80.8-0.5-1.01.00.20.30.2
Pavlov. Cond. change in total contacts4.44.76.71.92.5-2.52.52.6-2.22.42.42.42.4-1.81.72.1-2.51.71.7-2.51.1-1.12.42.51.6
Pavlov. Cond. index score2.22.84.22.02.0-2.02.02.0-1.92.01.81.71.7-1.61.51.6-1.81.61.6-1.7-0.20.21.41.40.9
Pavlov. Cond. latency score2.83.65.32.12.3-2.32.22.2-2.02.22.12.02.0-1.91.81.9-2.11.81.8-2.00.2-0.21.71.71.2
Pavlov. Cond. lever contacts2.83.34.91.72.2-2.22.12.2-1.71.92.01.81.8-1.91.91.9-2.01.81.8-1.90.7-0.71.81.81.4
Pavlov. Cond. magazine entry number1.01.22.6-1.6-1.61.6-1.3-1.41.3-1.3-1.3-0.9-0.91.0-0.9-0.91.0-1.0-1.01.00.6-0.5-0.7-0.8-0.5
Pavlov. Cond. intertrial magazine entries0.20.20.90.5-0.10.10.60.5-0.60.60.10.90.90.3-0.30.2-0.6-0.3-0.3-0.60.00.10.40.5-0.4
Pavlov. Cond. lever-magazine prob. diff.2.42.94.62.02.1-2.12.02.1-1.92.01.91.81.8-1.71.61.7-1.81.61.6-1.7-0.00.01.51.51.0
Pavlov. Cond. response bias1.41.73.01.71.7-1.71.61.7-1.51.51.51.21.2-1.31.21.2-1.31.31.3-1.3-0.20.21.01.10.7
Pavlov. Cond. lever latency0.30.41.71.30.6-0.60.70.7-1.10.80.60.50.50.2-0.30.1-0.5-0.2-0.2-0.5-1.11.00.10.3-0.4
Pavlov. Cond. magazine entry latency2.12.47.3-2.7-1.81.8-1.5-1.52.2-2.1-1.5-1.6-1.70.5-0.7-1.11.4-0.5-0.51.32.2-2.2-0.3-0.70.5
Pavlov. Cond. change in total contacts0.40.61.4-1.1-1.11.1-0.9-0.91.2-1.0-1.0-0.8-0.80.2-0.1-0.50.9-0.4-0.40.90.3-0.2-0.7-0.8-0.4
Pavlov. Cond. index score0.70.83.0-1.7-1.01.0-0.8-0.91.4-1.2-0.9-0.7-0.8-0.20.1-0.30.60.10.10.61.7-1.5-0.0-0.30.6
Pavlov. Cond. latency score0.50.72.3-1.5-1.01.0-0.8-0.81.2-1.0-0.8-0.7-0.7-0.10.0-0.30.50.10.10.51.4-1.4-0.0-0.20.5
Pavlov. Cond. lever contacts0.60.82.3-1.5-1.01.0-1.0-1.01.4-1.1-1.0-0.8-0.90.5-0.4-0.60.8-0.5-0.50.81.0-0.8-0.5-0.6-0.2
Pavlov. Cond. magazine entry number0.70.83.71.60.8-0.80.60.6-1.31.20.60.70.80.10.10.4-0.6-0.0-0.0-0.6-1.91.8-0.20.1-0.8
Pavlov. Cond. intertrial magazine entries0.70.96.01.3-0.00.00.00.0-0.90.9-0.10.10.10.7-0.6-0.3-0.1-0.7-0.7-0.1-2.52.4-0.9-0.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.60.72.7-1.6-1.01.0-0.8-0.81.3-1.1-0.8-0.6-0.7-0.20.0-0.30.60.10.10.61.6-1.5-0.0-0.20.5
Pavlov. Cond. response bias1.41.85.3-2.3-1.61.6-1.5-1.52.1-1.9-1.5-1.4-1.50.6-0.6-1.01.3-0.6-0.61.41.6-1.4-0.6-0.9-0.0
Time in closed arm before self-admin0.10.10.40.20.1-0.10.40.3-0.0-0.10.30.60.4-0.50.20.3-0.00.20.2-0.00.2-0.10.20.10.3
Time in closed arm after self-admin0.10.10.4-0.1-0.30.3-0.1-0.1-0.30.6-0.00.20.3-0.40.10.2-0.60.40.4-0.70.2-0.10.20.50.3
Time in open arm before self-admin0.20.32.00.6-0.30.3-0.4-0.1-0.20.1-0.2-0.2-0.10.10.0-0.10.30.00.00.3-1.41.2-0.7-0.6-0.6
Time in open arm after self-admin0.30.31.1-0.5-0.20.2-0.4-0.40.9-1.0-0.4-0.6-0.60.4-0.3-0.41.0-0.4-0.41.00.0-0.0-0.5-0.8-0.3
Bone: periosteal estimation0.81.64.92.21.5-1.51.31.3-1.51.01.40.80.8-1.31.31.1-0.51.31.3-0.5-1.81.70.20.20.6
Bone: periosteal perimeter1.01.75.32.31.7-1.71.51.5-1.71.31.51.11.1-1.21.21.2-0.91.11.1-0.8-1.51.40.50.60.5
Bone: post-yield work1.41.95.90.4-1.41.4-0.9-0.90.5-1.2-1.1-1.2-1.11.1-1.1-1.11.7-1.3-1.31.7-2.32.4-1.7-1.7-1.5
Progressive ratio test 1 active lever presses1.71.74.20.1-1.21.2-0.9-0.70.5-0.7-1.1-0.9-0.81.7-1.4-1.21.3-1.4-1.41.3-2.01.9-1.7-1.6-1.9
Progressive ratio test 1 breakpoint1.92.04.0-0.2-1.41.4-1.1-0.90.7-0.9-1.3-1.1-1.11.9-1.5-1.41.4-1.6-1.61.3-1.91.8-1.8-1.6-2.0
Progressive ratio test 1 inactive lever presses0.20.20.60.0-0.60.6-0.2-0.20.1-0.4-0.3-0.6-0.60.7-0.8-0.70.5-0.2-0.20.4-0.50.4-0.3-0.3-0.1
Progressive ratio test 2 active lever presses0.40.41.60.90.1-0.10.30.3-0.91.10.10.60.80.20.10.4-0.6-0.3-0.3-0.6-1.31.0-0.30.1-1.0
Progressive ratio test 2 breakpoint0.40.41.80.90.1-0.10.30.3-0.91.10.10.60.80.30.00.4-0.6-0.2-0.2-0.6-1.31.1-0.30.0-1.0
Progressive ratio test 2 inactive lever presses0.20.30.70.2-0.50.5-0.00.2-0.50.6-0.30.30.50.7-0.5-0.0-0.4-0.8-0.8-0.5-0.60.5-0.10.2-0.8
Incentive Sensitization - Responses0.30.31.30.60.1-0.10.40.2-0.81.10.10.71.0-0.20.30.6-0.9-0.0-0.0-0.9-0.50.20.20.5-0.5
Incentive Sensitization - Breakpoint0.20.21.00.50.1-0.10.40.1-0.71.00.10.60.9-0.20.30.6-0.9-0.0-0.0-0.8-0.30.00.20.5-0.4
Sum of active levers in priming session hrs 5-60.20.21.30.2-0.10.1-0.3-0.50.0-0.1-0.2-0.3-0.20.3-0.3-0.30.4-0.2-0.20.4-1.11.1-0.8-0.7-0.6
Progressive ratio0.10.21.20.40.2-0.2-0.3-0.2-0.40.40.1-0.00.10.00.10.1-0.1-0.2-0.2-0.2-1.01.1-0.4-0.1-0.5
Food seeking constrained by brief footshock0.10.10.50.3-0.00.0-0.2-0.0-0.40.6-0.10.20.10.4-0.3-0.1-0.3-0.1-0.1-0.3-0.70.5-0.20.0-0.4
Seeking ratio, punishment vs. effort0.10.10.2-0.2-0.40.40.00.00.3-0.3-0.3-0.1-0.30.2-0.3-0.30.20.00.00.30.3-0.5-0.0-0.2-0.1
Retroperitoneal fat weight0.10.31.00.40.1-0.1-0.2-0.50.1-0.40.1-0.2-0.2-0.70.40.20.60.80.80.6-0.91.0-0.6-0.70.3
Reaction time number correct0.71.03.2-1.8-0.90.9-1.3-1.11.4-1.3-1.1-0.8-0.90.7-1.1-1.01.0-0.7-0.70.90.8-0.7-0.6-0.7-0.2
Reaction time mean minus median1.11.52.40.51.3-1.31.21.2-0.80.91.31.41.4-1.21.21.3-1.31.11.1-1.31.3-1.31.51.51.4
Reaction time mean minus median AUC0.60.82.0-0.30.7-0.70.50.6-0.40.60.70.80.9-0.90.90.9-1.00.80.8-1.01.4-1.41.21.21.3
Reaction time num false alarms0.81.12.30.91.0-1.01.20.9-1.31.51.10.90.9-0.70.70.9-1.41.01.0-1.40.1-0.31.01.20.8
Reaction time num false alarms AUC0.40.51.10.50.8-0.80.90.6-0.81.00.80.50.6-0.40.40.5-1.10.60.6-1.10.4-0.50.81.00.6
Reaction time trials correct on left0.71.03.2-1.8-0.90.9-1.3-1.11.4-1.3-1.1-0.8-0.90.7-1.1-1.01.0-0.7-0.70.90.8-0.7-0.6-0.7-0.2
Reaction time trials on left0.71.13.5-1.9-0.90.9-1.3-1.11.5-1.3-1.1-0.9-1.00.7-1.2-1.11.0-0.7-0.71.00.8-0.7-0.6-0.7-0.2
Reaction time mean0.10.10.40.40.0-0.00.20.3-0.40.30.10.30.70.2-0.30.1-0.2-0.2-0.2-0.3-0.40.60.10.2-0.2
Reaction time mean AUC0.10.10.50.2-0.40.4-0.1-0.1-0.10.0-0.2-0.00.30.6-0.7-0.30.1-0.5-0.50.1-0.60.7-0.3-0.2-0.6
Median of all reaction times0.20.31.50.4-0.40.4-0.1-0.1-0.30.1-0.3-0.00.30.7-0.8-0.30.2-0.6-0.60.1-1.01.2-0.5-0.3-0.8
Reaction time omissions0.40.61.4-1.2-0.90.9-1.0-0.91.1-1.0-0.7-0.8-0.70.3-0.7-0.70.8-0.1-0.10.80.3-0.3-0.6-0.70.0
Reaction time false alarm rate1.01.42.81.61.3-1.31.51.2-1.61.71.41.11.1-0.81.11.1-1.51.01.0-1.5-0.30.21.01.20.6
Reaction time premature initiation rate1.21.64.3-0.21.0-1.00.70.6-0.40.61.20.60.8-1.61.31.1-1.11.71.7-1.12.0-1.91.51.42.1
Reaction time premature initiations0.40.63.3-1.30.0-0.0-0.4-0.40.7-0.40.1-0.3-0.2-0.80.20.1-0.10.90.9-0.11.8-1.70.60.41.4
Std. dev. reaction times0.10.10.7-0.40.1-0.10.10.20.00.00.20.30.4-0.0-0.10.2-0.30.10.1-0.40.8-0.80.50.50.5
Reaction time trials completed0.71.13.5-1.9-0.90.9-1.3-1.11.5-1.3-1.1-0.9-1.00.7-1.2-1.11.0-0.7-0.71.00.8-0.7-0.6-0.7-0.2
Reaction time trials AUC0.40.62.2-1.5-0.70.7-1.1-0.81.2-1.0-0.9-0.6-0.70.6-1.0-0.90.7-0.6-0.60.70.7-0.5-0.5-0.6-0.2
Run reversals in cocaine runway, females1.11.13.1-1.5-0.90.9-0.8-1.11.7-1.8-0.8-1.1-1.30.6-0.6-0.91.3-0.5-0.51.31.3-1.2-0.4-0.70.2
Run reversals in cocaine runway, males0.10.10.70.2-0.00.00.00.2-0.60.80.00.40.5-0.1-0.00.2-0.70.00.0-0.7-0.10.30.20.5-0.2
Latency to leave start box in cocaine runway1.41.54.3-0.40.6-0.60.70.9-0.70.80.91.11.1-0.80.50.8-1.31.31.3-1.52.0-2.11.71.82.1
Latency to leave start box in cocaine runway, F3.03.36.00.41.4-1.41.61.8-1.31.41.62.02.2-1.61.21.7-1.91.91.9-2.02.1-2.22.32.32.4
Latency to leave start box in cocaine runway, M0.20.20.9-0.9-0.60.6-0.9-0.60.3-0.3-0.4-0.4-0.60.5-0.6-0.60.20.00.00.00.4-0.4-0.10.00.4
Std. dev. time between licks in bursts2.93.47.11.62.0-2.01.71.7-1.41.42.01.71.6-2.62.72.3-1.42.52.5-1.40.4-0.41.51.42.1
Total sessions with >9 infusions0.70.84.31.80.5-0.50.70.8-0.80.40.60.0-0.1-0.10.40.20.20.90.90.3-2.12.0-0.6-0.6-0.3
Short access day 1 total inactive lever presses0.20.20.6-0.1-0.50.5-0.4-0.30.1-0.4-0.3-0.5-0.60.6-0.6-0.60.6-0.0-0.00.5-0.80.8-0.6-0.6-0.2
Short access day 10 total inactive lever presses1.11.22.9-1.7-1.01.0-1.0-1.21.4-1.6-1.0-0.9-0.80.9-1.0-0.91.1-1.2-1.21.01.3-1.4-0.2-0.4-0.0
Short access day 1 total infusions0.50.51.40.90.6-0.60.91.1-0.80.60.90.60.6-0.40.50.6-0.51.21.2-0.6-0.10.20.60.50.9
Short access day 10 total infusions0.70.71.9-0.5-1.01.0-0.7-0.60.7-0.7-0.9-1.1-0.91.4-1.3-1.10.7-0.9-0.90.7-0.30.1-0.7-0.7-0.8
Short access total infusions0.30.41.00.60.6-0.60.81.0-0.60.50.70.40.4-0.10.30.4-0.50.90.9-0.60.1-0.20.60.60.7
Short access day 1 locomotion0.10.10.60.4-0.10.1-0.0-0.0-0.10.2-0.0-0.4-0.30.4-0.5-0.40.00.10.10.1-0.70.8-0.4-0.2-0.4
Short access day 10 total locomotion1.01.12.1-0.1-1.01.0-0.8-0.80.7-1.0-0.9-1.3-1.41.2-1.2-1.31.2-0.8-0.81.2-1.41.3-1.2-1.2-0.9
Short access total locomotion0.91.02.3-0.6-1.01.0-0.8-0.91.0-1.1-0.8-1.5-1.51.2-1.2-1.31.1-0.4-0.41.1-0.40.3-0.9-1.0-0.5
One hour access (0.3 mA shock)1.01.27.11.90.6-0.60.60.5-1.51.50.50.60.8-0.30.40.6-0.60.50.5-0.6-2.72.5-0.6-0.2-0.8
Compulsive drug intake0.20.20.80.00.6-0.60.20.30.3-0.50.30.40.4-0.90.90.70.40.40.40.40.2-0.30.1-0.20.5
One hour access (shock baseline)0.50.63.21.1-0.20.20.20.0-1.11.3-0.00.10.20.4-0.5-0.1-0.7-0.1-0.1-0.7-1.81.7-0.5-0.0-1.0
Social response proportion0.91.03.0-1.5-1.71.7-1.4-1.20.6-0.3-1.4-1.1-0.71.0-1.3-1.00.2-1.0-1.00.10.5-0.5-0.5-0.2-0.5
Social responses0.30.41.50.3-0.90.9-0.6-0.3-0.40.6-0.6-0.3-0.10.2-0.5-0.3-0.2-0.2-0.2-0.1-1.11.2-0.7-0.4-0.9
Social time0.40.51.3-1.1-1.01.0-0.5-0.40.7-0.9-0.7-0.7-0.70.4-0.5-0.60.5-0.6-0.60.41.1-1.10.20.10.5
Soleus weight0.20.71.10.61.0-1.01.01.0-0.60.90.70.90.9-0.70.70.8-1.00.80.8-0.90.8-0.81.00.90.5
Bone: stiffness0.10.20.9-0.2-0.20.20.00.00.2-0.40.1-0.0-0.0-0.80.80.40.30.80.80.20.4-0.40.2-0.01.0
Tibialis anterior weight0.00.10.30.10.4-0.40.40.5-0.10.20.30.30.3-0.20.30.3-0.30.30.3-0.30.5-0.60.50.30.3
Time to tail flick, vehicle, before self-admin2.32.33.90.91.4-1.41.41.6-1.51.51.42.01.9-1.31.21.6-1.81.41.4-1.81.2-1.01.81.91.6
Time to tail flick, vehicle, after self-admin0.50.52.6-0.40.4-0.40.60.5-0.20.40.40.10.2-0.00.20.2-0.80.20.2-0.81.6-1.61.11.00.7
Time to tail flick, test, before self-admin0.60.62.0-0.20.6-0.60.70.8-0.50.60.60.60.4-0.50.50.4-0.90.40.4-1.01.4-1.21.11.21.0
Time to tail flick, test, after self-admin0.60.73.6-0.80.4-0.40.30.20.4-0.30.40.1-0.1-0.60.60.3-0.30.80.8-0.31.9-1.90.90.71.4
Delta time to tail flick, vehicle, before/after SA1.61.63.1-1.5-1.21.2-1.1-1.31.6-1.4-1.3-1.7-1.81.3-1.3-1.51.1-1.1-1.11.20.7-0.7-0.8-1.0-0.9
Delta time to tail flick, test, before/after SA0.20.20.7-0.6-0.20.2-0.3-0.50.8-0.8-0.2-0.5-0.5-0.0-0.1-0.20.70.10.10.70.4-0.5-0.2-0.40.3
Tibia length7.120.032.15.74.8-4.85.25.2-5.65.44.75.05.0-4.14.34.7-4.74.24.2-4.7-1.21.23.63.92.8
Ambulatory time before self-admin1.21.22.31.21.3-1.31.11.4-1.00.81.21.41.2-1.31.31.3-0.61.51.5-0.6-0.50.40.70.50.9
Ambulatory time after self-admin0.30.31.10.1-0.40.4-0.5-0.30.0-0.2-0.4-0.3-0.40.8-0.8-0.60.5-0.4-0.40.4-1.10.9-0.6-0.6-0.7
Bone: tissue strength1.11.13.01.70.9-0.91.21.2-1.20.71.21.01.0-1.21.31.2-0.41.21.2-0.4-1.01.10.40.40.7
Total heroin consumption0.80.96.71.60.1-0.10.40.4-1.21.10.10.20.50.3-0.40.0-0.3-0.2-0.2-0.2-2.62.4-0.7-0.4-1.2
Bone: trabecular number0.20.30.8-0.6-0.80.8-0.6-0.50.7-0.9-0.6-0.8-0.90.4-0.4-0.60.8-0.3-0.30.80.0-0.0-0.5-0.50.0
Bone: trabecular spacing0.10.10.30.10.5-0.50.30.2-0.30.40.20.50.5-0.10.00.2-0.4-0.0-0.0-0.40.1-0.20.30.3-0.1
Bone: trabecular thickness0.40.50.9-0.7-0.90.9-0.8-0.80.8-0.8-0.8-0.7-0.80.6-0.5-0.60.8-0.5-0.50.8-0.30.2-0.8-0.8-0.5
Bone: trabecular tissue density0.71.01.8-0.00.7-0.70.70.7-0.70.80.81.21.2-1.00.81.0-1.20.90.9-1.21.3-1.21.31.31.3
Water consumed over 24 hours0.20.20.70.10.5-0.50.50.5-0.00.10.40.20.2-0.40.30.3-0.30.50.5-0.30.8-0.80.60.40.6
Number of responses in last shaping day1.11.12.91.51.2-1.21.11.1-1.11.01.30.40.4-1.11.20.9-0.71.71.7-0.7-0.50.60.50.61.1