Hub : Genes

Tmem161a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Tmem161a 0.06 0.05 7.3e-03 0.01 0.01 0 0 1.2e-02 5.0e-02 8.6e-02 1.6e-01
2 NAcc gene expression Tmem161a 0.11 0.05 4.8e-12 0.08 0.08 0.08 0.08 4.0e-12 3.8e-12 1.5e-12 1.4e-12
3 Brain gene expression Tmem161a 0.08 0.04 2.1e-06 0.09 0.07 0.08 0.09 1.6e-08 6.6e-07 1.0e-07 2.4e-08
4 BLA gene expression Tmem161a 0.26 0.13 6.5e-05 0.06 0.09 0.06 0.07 2.8e-04 1.3e-05 3.5e-04 1.1e-04
5 Adipose alternative TSS XM_039094719.2 0.25 0.12 6.5e-03 -0 0.02 0.01 0 4.2e-01 3.8e-03 1.3e-02 3.4e-01
6 Liver gene expression Tmem161a 0.02 0.01 3.4e-03 0 0.02 0 0.01 1.2e-01 5.2e-03 1.9e-01 6.9e-02
7 LHb gene expression Tmem161a 0.22 0.11 6.9e-03 0.05 -0.01 0.03 0.05 2.1e-02 5.4e-01 7.7e-02 3.1e-02
8 Adipose alternative TSS XM_063275592.1 0.34 0.14 1.9e-03 -0 0.03 0.04 0 6.9e-01 2.6e-04 1.0e-05 8.5e-02
9 PL gene expression Tmem161a 0.07 0.04 3.8e-05 0.04 0.03 0.03 0.03 4.8e-05 2.2e-04 3.1e-04 1.7e-04
10 LHb alternative TSS XM_039094719.2 0.19 0.11 2.5e-03 0.14 0.09 0.12 0.12 2.7e-04 4.8e-03 8.5e-04 7.6e-04
11 LHb alternative TSS XM_063275592.1 0.25 0.13 7.0e-04 0.16 0.11 0.13 0.13 1.0e-04 1.2e-03 4.6e-04 6.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density3.86.612.6-2.5-3.3-2.8-3.42.0-0.8-3.5-1.5-3.4-1.51.5
Area under the delay curve0.30.31.20.30.20.0-0.6-0.50.30.2-1.10.00.8-0.8
BMI with tail1.03.57.6-2.5-2.3-2.4-2.2-1.0-2.8-1.20.3-1.01.6-1.6
BMI without tail2.06.213.1-3.2-3.1-3.2-2.6-0.7-3.6-1.3-1.3-1.62.5-2.5
Body weight3.716.030.3-5.5-5.3-5.2-5.2-1.6-4.9-3.8-0.8-3.62.2-2.2
Weight adjusted by age1.31.94.1-1.7-1.5-1.4-0.90.0-2.0-1.0-0.5-1.41.7-1.7
Bone surface2.03.78.0-2.0-2.5-2.3-2.81.5-0.8-2.6-0.8-2.3-0.90.9
Bone volume3.15.610.4-2.7-3.2-2.9-3.21.5-1.4-3.2-1.0-3.0-0.80.8
Breakpoint value in progressive ratio session0.70.96.4-0.30.80.80.5-1.0-0.20.32.50.70.2-0.2
Number of licking bursts0.30.41.20.70.20.5-0.2-1.10.90.50.40.5-0.80.8
Context. condit. distance diff. score0.60.72.01.10.40.50.8-0.51.00.40.10.1-1.41.4
Locomotion velocity, session 10.70.82.70.90.60.40.40.10.11.6-0.51.70.8-0.8
Locomotion distance, session 10.60.71.81.30.50.60.11.21.30.7-1.00.6-0.50.5
Locomotion velocity, session 21.21.44.0-0.3-0.6-0.8-0.6-1.1-1.30.9-1.40.92.0-2.0
Locomotion distance, session 20.60.82.41.30.91.00.31.21.60.6-0.50.8-0.20.2
Locomotion velocity, session 32.22.54.62.01.81.72.1-0.81.11.80.92.0-1.11.1
Locomotion distance, session 30.91.03.20.3-0.4-0.1-0.21.50.8-0.6-0.5-0.7-1.81.8
Stereotopy head waving bouts, day 33.33.86.32.02.22.21.7-2.52.31.01.81.1-2.02.0
Stereotopy head waving duration, day 31.92.36.31.61.71.61.3-2.51.51.11.31.0-1.21.2
Locomotion velocity, session 70.90.91.81.21.31.21.20.50.91.10.41.2-0.00.0
Locomotion distance, session 70.40.51.30.80.91.10.50.51.10.21.00.4-0.30.3
Stereotopy head waving bouts, day 70.30.30.90.20.40.40.4-0.90.6-0.20.5-0.1-0.90.9
Stereotopy head waving duration, day 70.40.52.90.30.60.50.9-1.70.10.40.90.4-0.40.4
Locomotion velocity, session 83.33.98.83.02.42.32.5-0.81.72.70.52.4-0.20.2
Locomotion distance, session 80.40.51.51.20.40.50.20.81.20.5-0.60.5-0.70.7
Degree of sensitization distance0.80.81.30.71.11.00.7-0.80.30.81.01.11.1-1.1
Degree of sensitization stereotypy0.20.30.5-0.6-0.6-0.5-0.3-0.1-0.2-0.7-0.2-0.7-0.50.5
Conditioned locomotion0.10.10.4-0.30.10.2-0.0-0.60.4-0.40.4-0.10.0-0.0
Cocaine response after cond. corrected0.30.30.70.10.50.40.8-0.80.4-0.20.60.1-0.80.8
Cocaine response after cond. not corrected0.80.92.30.91.31.21.5-0.90.80.70.90.9-0.40.4
Cocaine response before conditioning1.11.33.01.51.31.31.00.20.61.7-0.01.51.0-1.0
Saline control response0.50.74.00.3-0.5-0.5-0.31.60.10.1-2.0-0.10.1-0.1
Bone: connectivity density4.06.211.4-2.3-3.3-3.0-3.42.5-1.1-2.8-2.6-3.0-0.60.6
Bone: cortical apparent density0.40.52.4-0.4-0.2-0.3-0.41.5-0.30.2-1.30.00.6-0.6
Bone: cortical area4.67.115.7-4.0-3.2-3.2-2.8-0.6-3.1-3.51.4-3.0-0.30.3
Bone: cortical porosity0.10.10.3-0.10.20.1-0.30.0-0.10.20.60.10.4-0.4
Bone: cortical porosity0.00.00.2-0.20.1-0.0-0.50.0-0.0-0.00.4-0.00.1-0.1
Bone: cortical thickness3.65.911.8-3.4-2.8-2.6-2.5-0.6-2.1-3.41.6-3.1-1.51.5
Bone: cortical thickness3.13.79.0-1.9-1.5-1.2-1.5-1.20.1-2.91.6-3.0-2.22.2
Bone: cortical tissue density0.30.52.3-0.2-0.0-0.1-0.31.5-0.20.4-1.30.20.6-0.6
Condit. Reinf. active minus inactive responses0.80.92.5-0.7-1.1-0.9-1.3-0.50.2-1.6-0.4-1.6-0.50.5
Condit. Reinf. active-inactive response ratio1.92.05.4-1.2-1.6-1.1-1.50.40.2-2.3-0.3-2.3-1.41.4
Condit. Reinf. active responses0.60.81.9-0.7-1.1-0.9-1.4-0.8-0.1-1.1-0.5-1.3-0.00.0
Condit. Reinf. inactive responses0.50.71.6-0.3-0.6-0.9-0.7-0.3-1.00.4-1.00.11.3-1.3
Incentive salience index mean0.60.82.5-0.9-0.9-0.9-1.6-1.0-0.2-1.1-0.2-0.90.3-0.3
Condit. Reinf. lever presses0.50.72.4-0.8-0.6-0.8-1.6-1.4-0.4-0.50.20.00.7-0.7
Condit. Reinf. active minus inactive responses0.10.10.80.40.20.20.50.90.3-0.1-0.4-0.1-0.10.1
Condit. Reinf. active-inactive response ratio0.10.20.3-0.5-0.4-0.5-0.2-0.4-0.5-0.50.3-0.4-0.30.3
Condit. Reinf. active responses0.81.12.21.41.11.11.51.30.91.1-0.91.00.2-0.2
Condit. Reinf. inactive responses2.53.36.22.32.12.02.51.31.32.5-0.82.20.8-0.8
Condit. Reinf. lever presses0.60.81.40.40.80.61.0-0.7-0.41.10.51.11.2-1.2
Condit. Reinf. lever reinforcers received0.40.61.50.90.80.81.20.70.30.8-0.40.80.5-0.5
Conditioned reinforcement - actives1.11.93.8-1.5-1.9-2.0-1.20.2-1.8-1.1-1.5-1.10.9-0.9
Conditioned reinforcement - inactives4.36.311.7-3.1-3.4-3.4-2.3-1.0-3.3-2.4-1.9-2.41.4-1.4
Conditioned locomotion1.11.43.6-1.1-1.5-1.7-0.9-0.2-1.5-0.5-1.9-1.00.8-0.8
Patch foraging indifference point 0 sec1.22.210.5-1.1-0.5-0.9-0.7-3.2-1.6-0.42.00.31.4-1.4
Patch foraging indifference point AUC0.81.23.30.21.41.10.6-1.50.01.11.80.81.0-1.0
Delay disc. indifference point, 0s delay2.12.34.82.22.12.11.1-0.72.02.0-0.21.7-0.10.1
Delay disc. indifference point, 16s delay0.50.61.11.01.00.80.5-0.30.70.9-0.60.70.8-0.8
Delay disc. indifference point, 2s delay0.30.41.30.80.91.0-0.1-0.51.20.2-0.20.40.1-0.1
Delay disc. indifference point, 24s delay0.70.83.80.4-0.1-0.5-0.2-0.6-0.50.9-1.90.31.1-1.1
Delay disc. indifference point, 4s delay0.20.31.50.2-0.0-0.3-0.80.10.10.1-1.20.30.5-0.5
Delay disc. indifference point, 8s delay0.30.41.8-0.10.1-0.1-0.6-1.3-0.30.2-0.10.01.0-1.0
Indifference point function ln k1.11.84.5-1.2-2.1-2.1-1.60.8-1.0-1.4-1.5-1.2-0.30.3
Indifference point function log k1.11.84.5-1.2-2.1-2.1-1.60.8-1.0-1.4-1.5-1.2-0.30.3
Patch foraging total patch changes 0 sec1.63.113.0-1.6-0.9-1.3-1.1-3.6-2.1-0.62.10.11.6-1.6
Patch foraging total patch changes 12 sec1.01.36.50.20.80.40.5-2.6-0.50.81.51.01.2-1.2
Patch foraging total patch changes 18 sec1.82.78.90.62.01.81.5-2.20.31.03.02.00.8-0.8
Patch foraging total patch changes 24 sec0.61.05.2-0.10.60.40.2-2.3-0.1-0.42.20.00.6-0.6
Patch foraging total patch changes 6 sec1.52.29.9-0.00.80.30.3-3.1-0.91.01.61.32.0-2.0
Patch foraging time to switch 0 sec0.61.32.51.61.11.31.11.31.11.3-1.11.30.3-0.3
Patch foraging water rate 0 sec0.61.23.3-1.4-0.8-1.2-1.3-1.8-1.0-0.81.1-0.80.2-0.2
Patch foraging water rate 12 sec0.81.73.3-1.5-1.7-1.6-1.80.2-1.0-1.7-0.4-1.80.2-0.2
Patch foraging water rate 18 sec0.50.72.8-0.8-0.9-1.1-1.70.70.0-0.8-0.6-0.90.2-0.2
Patch foraging water rate 24 sec2.02.86.7-1.6-2.2-2.1-2.61.1-0.7-1.8-1.8-1.90.1-0.1
Patch foraging water rate 6 sec1.01.53.0-1.7-1.7-1.7-1.5-0.6-1.4-1.3-0.2-1.30.1-0.1
Seeking ratio, delayed vs. immediate footshock1.01.24.61.50.40.70.61.20.72.1-1.31.2-0.40.4
Distance traveled before self-admin0.20.31.0-0.3-0.3-0.4-0.0-0.9-1.00.80.10.50.5-0.5
Distance traveled after self-admin0.30.41.6-0.8-0.8-0.9-0.2-0.6-1.30.20.4-0.10.5-0.5
Extensor digitorum longus weight0.10.53.1-0.20.10.00.2-1.8-0.50.60.70.90.2-0.2
Bone: elastic displacement0.40.52.40.3-0.4-0.3-0.41.30.5-0.1-1.5-0.6-0.00.0
Bone: elastic work1.21.63.0-1.6-1.7-1.7-1.5-0.2-1.4-1.40.1-1.5-0.40.4
Bone: endosteal estimation0.30.61.9-0.6-0.6-0.8-0.7-0.4-0.9-0.1-0.20.21.4-1.4
Bone: endosteal perimeter0.51.22.9-1.5-1.2-1.4-0.8-0.8-1.7-1.30.7-0.60.4-0.4
Epididymis fat weight1.55.29.5-2.9-3.0-3.0-3.11.7-2.8-1.5-1.3-1.81.4-1.4
Delta time in closed arm before/after self-admin0.40.31.0-0.20.2-0.1-0.4-1.0-0.00.2-0.00.81.0-1.0
Delta time in open arm before/after self-admin0.40.41.00.40.61.00.61.00.50.21.00.2-0.40.4
Diff in mean of infusions in LGA sessions1.11.43.0-0.20.30.20.7-1.4-1.41.31.01.31.7-1.7
Delay discount exponential model param0.30.31.3-0.00.00.30.70.6-0.00.11.10.2-0.80.8
Extinction: sum of active levers before priming0.20.21.1-0.10.10.1-0.81.00.3-0.20.3-0.2-0.40.4
Active lever presses in extinction session 60.30.30.50.60.50.50.70.50.30.70.30.7-0.10.1
Bone: final force4.47.015.7-4.0-2.7-2.8-2.7-2.7-3.1-2.92.3-2.31.2-1.2
Bone: final moment4.26.715.1-3.9-2.7-2.8-2.7-2.6-3.0-2.92.2-2.21.1-1.1
Food consumed during 24 hour testing period0.10.10.60.00.10.2-0.30.70.8-0.30.0-0.0-0.10.1
Glucose0.81.32.8-1.2-0.4-0.6-0.3-1.7-1.6-0.31.40.01.5-1.5
Heart weight0.91.43.1-1.0-1.5-1.3-0.9-0.2-0.4-1.6-1.8-1.7-0.60.6
Delay discount hyperbolic model param0.30.30.9-0.1-0.10.10.70.8-0.20.11.00.1-0.80.8
Intermittent access intake day 1-15 change0.81.54.4-1.2-1.5-1.2-1.01.3-0.6-1.8-0.7-2.1-0.40.4
Intermittent access intake escalation0.91.85.5-1.0-1.5-1.3-1.21.6-0.4-1.8-0.9-2.3-0.70.7
Intermittent access intake escalation 21.61.83.3-1.4-1.8-1.7-1.41.4-1.2-1.2-1.4-1.50.5-0.5
Intermitt. access day 1 inactive lever presses0.10.31.1-0.3-0.6-0.60.30.8-0.8-0.1-1.0-0.50.2-0.2
Intermitt. access day 15 inactive lever presses0.10.10.70.30.0-0.10.80.40.00.1-0.70.0-0.40.4
Intermitt. access escalation Index0.20.30.90.90.30.3-0.10.00.90.4-0.40.2-0.60.6
Intermittent access day 1 total infusions0.40.73.4-0.30.1-0.20.4-1.9-1.00.80.60.40.8-0.8
Intermittent access day 15 total infusions0.81.23.8-1.1-1.4-1.4-1.10.5-0.9-1.2-0.5-1.9-0.20.2
Intermittent access terminal intake (last 3 days)0.50.71.3-1.1-1.1-1.1-0.9-0.0-0.9-1.00.2-1.20.1-0.1
Intermittent access total infusions0.70.82.0-1.4-1.0-1.2-0.6-0.8-1.4-0.70.6-0.60.6-0.6
Intermittent access day 1 locomotion0.81.13.1-1.3-0.6-1.1-0.5-1.4-1.7-0.00.2-0.31.3-1.3
Intermittent access day 15 total locomotion0.30.51.2-1.1-0.8-0.9-0.9-0.0-0.8-0.90.1-0.60.2-0.2
Intermittent access total locomotion1.01.33.1-1.7-1.1-1.4-0.9-0.8-1.8-0.70.2-0.71.1-1.1
Intermittent access standard deviation0.40.82.9-0.6-1.2-1.1-0.60.7-0.9-0.2-1.7-0.70.5-0.5
Left kidney weight0.21.22.7-1.1-0.3-0.4-0.4-1.3-1.60.31.51.01.3-1.3
Right kidney weight0.83.811.0-2.7-1.8-2.1-1.8-0.4-3.3-0.30.10.12.5-2.5
Cocaine induced anxiety1.01.44.8-0.10.60.11.2-1.9-1.11.12.21.30.9-0.9
Post-drug Anxiety0.60.61.50.60.70.51.1-0.6-0.11.11.21.00.2-0.2
Baseline Anxiety0.80.92.71.10.40.7-0.21.71.60.1-1.2-0.0-0.90.9
Tail length0.72.95.3-2.0-2.3-2.3-2.00.1-2.1-1.0-1.9-1.31.2-1.2
Length with tail1.56.413.2-3.6-3.3-3.3-3.2-0.6-3.1-2.5-0.8-2.21.3-1.3
Length without tail1.44.410.3-3.2-2.4-2.3-2.4-0.8-1.8-3.21.0-2.4-0.30.3
Times rat made contact with spout0.10.10.5-0.2-0.1-0.0-0.7-0.10.50.0-0.00.2-0.50.5
Lifetime Intake1.11.33.1-1.6-1.3-1.5-0.9-1.2-1.8-0.90.1-1.00.7-0.7
Liver weight, left0.20.42.7-0.30.20.4-0.01.60.4-0.10.40.0-0.70.7
Liver weight, right1.93.46.2-2.5-1.9-2.1-1.91.1-2.5-0.9-1.3-0.92.1-2.1
Locomotor activity0.91.54.2-1.2-1.2-1.3-2.11.5-0.1-1.0-1.8-0.7-0.10.1
Locomotor testing distance1.01.96.9-0.3-1.2-1.1-1.62.20.5-1.0-2.6-0.8-0.80.8
Locomotor testing rearing0.61.26.20.1-0.7-0.9-1.32.00.2-0.2-2.5-0.3-0.00.0
Locomotion in novel chamber0.40.51.9-1.0-0.9-0.4-1.40.0-0.3-0.70.4-0.70.0-0.0
Locomotion in novel chamber post-restriction2.33.79.9-1.7-2.1-1.7-3.11.3-0.1-2.9-0.6-2.9-1.01.0
Fecal boli incidents, locomotor time 10.10.21.2-0.3-0.3-0.3-1.10.6-0.2-0.20.20.1-0.10.1
Change in fecal boli incidents, locomotor task2.12.14.21.41.91.72.0-1.40.91.80.81.80.5-0.5
Time >=10cm from walls, locomotor time 10.70.74.8-0.30.70.60.5-0.5-0.30.82.21.1-0.10.1
Bouts of movement, locomotor time 10.20.31.3-0.30.2-0.2-0.30.9-0.10.5-1.10.20.4-0.4
Total resting periods, locomotor time 10.30.31.60.10.30.0-0.11.20.20.5-1.30.30.3-0.3
Rest time, locomotor task time 10.30.30.60.80.30.50.5-0.70.40.8-0.60.50.6-0.6
Distance moved, locomotor task time 10.30.52.30.30.60.60.8-0.30.10.51.50.6-0.70.7
Vertical activity count, locomotor time 10.10.21.3-0.5-0.4-0.4-0.31.1-0.2-0.2-0.2-0.1-0.50.5
Time >=10cm from walls, locomotor time 20.81.22.30.90.81.30.90.61.50.21.30.1-1.51.5
Bouts of movement, locomotor time 20.40.61.20.61.01.01.0-1.10.60.51.10.40.2-0.2
Total resting periods, locomotor time 20.40.71.90.51.00.90.9-1.40.50.51.20.50.4-0.4
Rest time, locomotor task time 20.40.62.8-0.50.00.10.1-1.7-0.50.3-0.10.01.2-1.2
Distance moved, locomotor task time 20.40.51.60.50.10.20.41.20.3-0.10.60.0-1.31.3
Vertical activity count, locomotor time 20.81.14.30.2-0.3-0.10.11.30.6-0.70.5-0.6-2.12.1
Light reinforcement 10.20.41.3-0.10.40.30.3-0.8-0.20.60.51.10.9-0.9
Light reinforcement 20.91.43.80.31.10.91.0-1.9-0.41.21.81.60.9-0.9
Bone: marrow area0.20.51.5-0.6-0.5-0.8-0.7-0.4-0.8-0.1-0.30.21.2-1.2
Bone: maximum diameter1.62.95.4-2.3-1.8-1.8-1.5-1.6-1.9-2.31.8-1.8-0.40.4
Bone: maximum force4.37.717.3-4.2-3.1-3.2-3.3-2.0-3.2-3.31.9-2.60.7-0.7
Bone: maximum moment3.96.815.5-3.9-3.0-3.0-3.1-1.8-3.0-3.21.8-2.40.6-0.6
Mean time between licks in bursts1.02.54.5-1.9-2.0-2.1-1.7-0.5-2.1-0.9-1.3-1.11.5-1.5
Mean num. licks in bursts0.40.61.2-1.1-0.7-0.8-0.71.1-0.5-1.1-0.7-1.10.2-0.2
Cd content in liver3.84.212.2-2.4-2.4-2.0-2.2-0.1-0.8-3.20.2-3.5-1.31.3
Co content in liver0.30.31.30.20.40.50.5-0.70.4-0.21.2-0.2-0.80.8
Cu content in liver1.01.23.61.00.70.80.30.41.70.00.70.2-1.91.9
Fe content in liver0.50.61.10.71.01.01.00.70.80.90.00.9-0.10.1
K content in liver2.12.04.32.11.61.71.5-0.41.81.41.01.3-1.11.1
Mg content in liver0.50.51.40.70.40.50.6-0.30.60.31.20.1-1.21.2
Mn content in liver0.10.10.60.3-0.4-0.30.30.5-0.20.1-0.8-0.3-0.40.4
Na content in liver1.31.42.91.71.01.10.41.61.41.6-0.41.2-0.80.8
Rb content in liver0.70.82.0-0.8-0.9-0.7-0.3-1.4-0.4-1.40.7-1.2-0.80.8
Se content in liver0.91.02.90.60.50.80.70.40.80.11.7-0.1-1.71.7
Sr content in liver1.41.26.1-0.1-0.5-0.5-0.52.1-0.50.0-2.5-0.60.9-0.9
Zn content in liver0.10.10.30.20.30.20.60.3-0.10.30.10.10.2-0.2
Bone: minimum diameter1.83.37.9-2.8-2.3-2.5-2.20.1-2.6-1.80.6-1.40.4-0.4
Time in familiar zone, hab. session 11.51.44.1-0.7-1.0-1.0-0.90.9-1.0-0.1-2.0-0.51.8-1.8
Time in novel zone, hab. session 10.60.62.70.1-0.3-0.0-0.0-0.30.9-0.50.4-0.5-1.61.6
Total zone transitions, hab. session 10.20.30.90.3-0.1-0.1-0.70.90.30.3-0.70.30.7-0.7
Total locomotion distance, hab. session 10.60.93.80.5-0.4-0.3-1.22.00.8-0.0-1.8-0.10.5-0.5
Locomotion velocity, hab. session 10.50.62.90.7-0.00.0-0.71.70.70.4-1.20.50.6-0.6
Time in familiar zone, hab. session 20.70.84.0-0.1-0.7-0.9-0.21.1-0.70.2-2.00.10.9-0.9
Time in novel zone, hab. session 20.20.20.7-0.40.00.30.0-0.30.4-0.70.8-0.7-0.50.5
Total zone transitions, hab. session 20.10.10.20.20.30.40.40.30.40.10.50.20.0-0.0
Total locomotion distance, hab. session 20.30.41.6-0.0-0.5-0.2-0.51.30.7-0.7-1.0-0.7-0.30.3
Locomotion velocity, hab. session 20.30.41.70.2-0.4-0.1-0.51.30.7-0.4-1.0-0.5-0.20.2
Novel to familiar place preference ratio0.40.41.2-1.1-0.6-0.7-0.90.2-0.7-0.7-0.2-0.50.6-0.6
Novelty place preference0.20.20.6-0.8-0.4-0.4-0.60.1-0.5-0.5-0.2-0.30.6-0.6
Time in novel zone, NPP test0.20.20.5-0.7-0.3-0.3-0.50.3-0.2-0.4-0.3-0.10.5-0.5
Total zone transitions, NPP test0.30.41.60.60.60.6-0.20.21.30.20.70.2-0.90.9
Total locomotion distance, NPP test0.60.82.80.90.10.3-0.71.31.7-0.1-0.7-0.1-1.21.2
Locomotion velocity, NPP test0.50.72.31.10.30.4-0.71.11.50.1-0.60.1-1.01.0
Intraocular pressure0.40.61.1-0.9-1.0-1.0-0.4-0.8-0.9-1.0-0.6-0.7-0.20.2
Delta distance traveled before/after self-admin0.40.51.3-1.1-0.8-0.8-0.40.1-1.0-0.60.7-0.20.5-0.5
Delta ambulatory time before/after self-admin0.20.31.8-0.6-0.1-0.10.1-0.2-0.4-0.51.4-0.0-0.20.2
Parametrial fat weight1.84.211.7-2.5-2.2-2.4-1.6-1.1-3.4-0.4-1.0-0.32.6-2.6
Pavlov. Cond. lever latency0.20.31.40.1-0.1-0.10.91.0-0.20.3-1.20.00.1-0.1
Pavlov. Cond. magazine entry latency0.20.30.6-0.6-0.6-0.5-0.8-0.4-0.4-0.40.2-0.40.6-0.6
Pavlov. Cond. change in total contacts0.90.95.8-0.7-0.2-0.1-0.9-2.4-0.2-0.61.4-0.40.5-0.5
Pavlov. Cond. index score0.10.20.6-0.10.00.0-0.8-0.60.1-0.10.70.10.3-0.3
Pavlov. Cond. latency score0.20.31.00.30.40.4-0.5-1.00.50.21.00.40.2-0.2
Pavlov. Cond. lever contacts0.20.31.0-0.30.0-0.0-0.8-1.0-0.1-0.11.00.20.4-0.4
Pavlov. Cond. magazine entry number0.20.30.50.60.60.60.70.30.60.4-0.20.3-0.60.6
Pavlov. Cond. intertrial magazine entries1.61.95.30.0-1.0-0.7-1.10.71.0-1.4-1.3-1.6-2.32.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.7-0.00.10.1-0.5-0.70.10.10.80.20.1-0.1
Pavlov. Cond. response bias0.30.31.1-0.6-0.5-0.5-1.1-0.6-0.3-0.60.5-0.40.4-0.4
Pavlov. Cond. lever latency0.91.22.90.1-0.8-0.5-0.81.70.9-0.8-1.3-1.2-1.31.3
Pavlov. Cond. magazine entry latency0.70.95.2-0.30.60.60.5-1.6-0.70.42.30.50.2-0.2
Pavlov. Cond. change in total contacts1.01.65.90.21.10.91.1-2.4-0.50.82.11.11.1-1.1
Pavlov. Cond. index score1.21.66.0-0.20.90.70.9-2.4-0.90.82.31.01.0-1.0
Pavlov. Cond. latency score1.11.54.70.11.10.91.1-2.2-0.60.92.21.00.8-0.8
Pavlov. Cond. lever contacts0.91.33.40.11.00.71.1-1.9-0.71.01.51.31.1-1.1
Pavlov. Cond. magazine entry number1.11.45.80.8-0.4-0.2-0.32.11.3-0.4-2.4-0.5-0.90.9
Pavlov. Cond. intertrial magazine entries0.60.95.00.4-0.5-0.4-0.52.00.50.2-2.2-0.1-0.10.1
Pavlov. Cond. lever-magazine prob. diff.1.21.66.0-0.30.80.60.8-2.4-1.00.72.30.91.0-1.0
Pavlov. Cond. response bias0.91.33.4-0.40.70.40.7-1.9-1.20.81.81.11.1-1.1
Time in closed arm before self-admin1.41.76.0-0.5-0.9-1.30.5-2.0-2.40.80.20.41.6-1.6
Time in closed arm after self-admin1.21.33.5-0.8-1.0-1.40.1-1.9-1.90.2-0.30.11.2-1.2
Time in open arm before self-admin0.40.41.60.1-0.0-0.0-0.81.30.8-0.4-1.2-0.1-0.40.4
Time in open arm after self-admin1.21.35.50.4-0.00.5-0.62.31.4-0.8-0.5-1.0-1.51.5
Bone: periosteal estimation1.63.37.1-2.7-2.3-2.4-2.2-0.4-2.3-2.20.6-1.60.4-0.4
Bone: periosteal perimeter2.54.38.9-3.0-2.5-2.6-1.8-1.2-2.8-2.71.1-2.10.1-0.1
Bone: post-yield work0.30.51.1-0.6-0.3-0.3-0.8-0.20.2-1.01.1-0.4-0.80.8
Progressive ratio test 1 active lever presses1.11.36.2-1.1-0.3-0.6-0.3-2.5-1.50.01.20.11.2-1.2
Progressive ratio test 1 breakpoint1.01.25.7-1.0-0.3-0.6-0.3-2.4-1.40.01.10.01.1-1.1
Progressive ratio test 1 inactive lever presses0.60.92.8-0.9-1.2-1.4-0.30.2-1.7-0.3-1.1-0.60.7-0.7
Progressive ratio test 2 active lever presses0.40.51.4-0.9-0.7-0.8-0.5-0.9-1.2-0.40.3-0.50.6-0.6
Progressive ratio test 2 breakpoint0.30.41.0-0.8-0.6-0.7-0.5-0.7-1.0-0.40.2-0.50.5-0.5
Progressive ratio test 2 inactive lever presses0.50.82.4-1.0-0.9-1.1-0.6-1.5-1.1-0.80.5-0.60.3-0.3
Incentive Sensitization - Responses0.10.10.5-0.3-0.3-0.2-0.3-0.4-0.3-0.40.7-0.50.1-0.1
Incentive Sensitization - Breakpoint0.10.10.4-0.2-0.2-0.1-0.3-0.1-0.2-0.30.6-0.40.0-0.0
Sum of active levers in priming session hrs 5-62.11.94.80.40.20.9-0.51.92.0-1.40.1-1.1-2.22.2
Progressive ratio0.10.10.4-0.10.10.30.30.10.3-0.60.3-0.60.3-0.3
Food seeking constrained by brief footshock1.82.25.4-0.4-1.0-0.5-1.00.91.0-2.3-0.0-2.2-2.22.2
Seeking ratio, punishment vs. effort0.91.33.2-0.1-0.9-0.7-1.31.10.6-0.9-1.1-1.0-1.81.8
Retroperitoneal fat weight1.98.015.5-3.7-3.9-3.8-3.4-0.6-3.8-2.4-1.2-2.31.6-1.6
Reaction time number correct0.71.46.0-0.4-1.4-1.1-1.42.5-0.5-0.7-1.6-0.80.0-0.0
Reaction time mean minus median0.41.02.30.41.10.90.8-1.40.11.11.51.30.6-0.6
Reaction time mean minus median AUC0.41.02.60.61.00.80.9-1.6-0.01.21.31.10.7-0.7
Reaction time num false alarms1.01.49.3-0.30.30.50.7-2.0-0.6-0.83.00.2-0.50.5
Reaction time num false alarms AUC1.21.811.7-0.10.60.81.0-2.2-0.3-0.83.40.3-0.70.7
Reaction time trials correct on left0.71.46.0-0.4-1.4-1.1-1.42.5-0.5-0.7-1.6-0.80.0-0.0
Reaction time trials on left0.71.35.6-0.5-1.4-1.1-1.42.4-0.6-0.7-1.5-0.80.1-0.1
Reaction time mean0.50.71.8-0.60.3-0.10.6-1.3-1.20.41.20.51.0-1.0
Reaction time mean AUC0.71.12.00.11.00.51.2-1.4-0.81.11.41.11.1-1.1
Median of all reaction times0.40.51.6-0.70.1-0.20.6-1.1-1.30.11.00.10.7-0.7
Reaction time omissions1.01.54.6-0.90.3-0.20.2-2.1-1.60.52.00.61.3-1.3
Reaction time false alarm rate1.52.110.6-0.30.70.80.9-3.0-0.1-0.73.30.1-0.50.5
Reaction time premature initiation rate0.30.30.90.30.90.6-0.0-0.81.0-0.00.90.3-0.20.2
Reaction time premature initiations0.00.10.4-0.00.1-0.1-0.70.30.3-0.2-0.0-0.00.1-0.1
Std. dev. reaction times0.40.81.9-0.60.40.10.4-1.4-0.90.71.40.71.2-1.2
Reaction time trials completed0.71.35.6-0.5-1.4-1.1-1.42.4-0.6-0.7-1.5-0.80.1-0.1
Reaction time trials AUC0.81.65.6-0.7-1.6-1.3-1.62.4-0.8-0.8-1.6-1.00.3-0.3
Run reversals in cocaine runway, females1.81.84.1-1.8-1.6-1.7-1.1-1.5-2.0-1.00.1-1.30.9-0.9
Run reversals in cocaine runway, males1.71.73.51.11.51.41.30.11.10.91.91.4-1.41.4
Latency to leave start box in cocaine runway0.40.51.3-0.3-0.7-0.8-0.80.4-0.50.3-1.2-0.20.9-0.9
Latency to leave start box in cocaine runway, F0.70.81.4-0.9-1.1-1.1-1.20.0-0.7-0.4-1.0-0.80.9-0.9
Latency to leave start box in cocaine runway, M0.40.31.10.90.50.50.60.40.31.0-0.10.90.1-0.1
Std. dev. time between licks in bursts1.62.13.9-2.0-1.9-1.9-1.8-0.7-1.6-1.4-0.6-1.60.9-0.9
Total sessions with >9 infusions1.82.25.3-2.0-1.6-1.7-0.9-1.6-2.3-1.1-0.4-1.61.0-1.0
Short access day 1 total inactive lever presses1.62.15.8-1.2-2.1-2.0-1.20.0-1.5-1.1-2.4-1.20.4-0.4
Short access day 10 total inactive lever presses1.12.77.31.92.01.72.7-0.80.72.40.52.00.4-0.4
Short access day 1 total infusions3.24.37.8-2.4-2.8-2.7-2.3-0.5-2.4-1.9-2.1-2.30.8-0.8
Short access day 10 total infusions1.11.42.8-1.0-1.7-1.7-1.4-0.3-1.0-1.0-1.6-1.40.2-0.2
Short access total infusions1.21.53.1-1.4-1.5-1.6-1.1-1.4-1.8-0.8-0.7-1.00.9-0.9
Short access day 1 locomotion3.44.28.0-2.3-2.8-2.8-1.8-0.7-2.8-1.5-2.0-2.31.1-1.1
Short access day 10 total locomotion1.83.36.6-2.1-2.5-2.3-1.90.8-1.7-1.6-1.8-2.60.2-0.2
Short access total locomotion2.02.44.5-2.1-2.0-2.0-1.6-0.7-1.8-1.6-0.6-2.00.4-0.4
One hour access (0.3 mA shock)0.91.02.3-0.6-1.1-1.0-1.2-0.9-0.3-1.4-0.3-1.5-0.90.9
Compulsive drug intake0.81.01.81.11.21.30.8-0.41.30.30.80.2-1.21.2
One hour access (shock baseline)1.11.73.6-1.5-1.8-1.9-1.3-0.6-1.7-1.2-0.4-1.50.5-0.5
Social response proportion3.03.410.5-2.2-2.1-1.7-2.0-0.7-0.7-3.20.3-3.1-0.50.5
Social responses1.92.46.1-1.2-1.8-1.5-2.20.80.2-2.3-1.2-2.5-0.90.9
Social time0.30.40.90.20.40.50.2-0.80.8-0.50.2-0.6-0.90.9
Soleus weight0.51.55.7-1.3-0.8-1.0-1.0-2.4-1.8-0.21.20.11.0-1.0
Bone: stiffness2.54.09.3-3.1-2.0-2.1-1.8-2.3-2.6-2.21.6-1.41.1-1.1
Tibialis anterior weight0.20.51.4-1.1-1.0-0.8-1.20.4-0.6-0.4-0.8-0.10.3-0.3
Time to tail flick, vehicle, before self-admin0.30.31.2-0.8-0.2-0.4-0.0-0.3-0.3-1.10.6-0.80.3-0.3
Time to tail flick, vehicle, after self-admin0.50.71.60.0-0.1-0.10.61.1-0.60.8-1.30.71.2-1.2
Time to tail flick, test, before self-admin0.90.92.8-0.8-0.7-0.5-0.1-1.7-0.8-0.91.6-0.9-0.60.6
Time to tail flick, test, after self-admin0.60.72.30.31.01.20.9-0.60.9-0.31.5-0.2-0.50.5
Delta time to tail flick, vehicle, before/after SA0.90.83.70.90.20.20.41.20.21.2-1.91.00.4-0.4
Delta time to tail flick, test, before/after SA0.30.31.90.10.20.2-0.41.40.7-0.2-0.8-0.30.2-0.2
Tibia length0.30.81.9-1.2-1.0-1.1-1.1-1.4-0.9-0.80.8-0.50.3-0.3
Ambulatory time before self-admin0.50.71.9-0.3-0.5-0.7-0.1-0.8-1.41.2-0.20.71.1-1.1
Ambulatory time after self-admin0.70.93.0-1.3-1.0-1.2-0.6-0.7-1.70.20.7-0.00.8-0.8
Bone: tissue strength0.70.72.5-0.30.40.10.4-0.0-0.80.70.20.91.6-1.6
Total heroin consumption0.70.83.8-0.30.80.60.4-1.4-0.50.52.01.10.6-0.6
Bone: trabecular number4.16.813.4-2.6-3.5-3.2-3.72.1-1.3-3.1-2.3-3.2-0.70.7
Bone: trabecular spacing0.91.22.00.91.41.31.4-1.00.21.31.21.20.7-0.7
Bone: trabecular thickness2.22.86.1-2.0-2.0-1.8-2.50.8-0.5-2.4-0.2-2.1-1.01.0
Bone: trabecular tissue density0.20.41.50.20.80.70.00.40.20.61.20.70.4-0.4
Water consumed over 24 hours0.40.51.6-1.0-0.4-0.3-1.3-0.40.1-1.00.8-0.80.1-0.1
Number of responses in last shaping day1.21.33.1-1.1-1.3-1.1-1.7-0.5-0.3-1.7-0.3-1.8-0.70.7