Tmeff2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IL	gene expression	Tmeff2	0.25	0.14	1.4e-03	0.04	0.06	0.06	0.06	4.0e-02	1.5e-02	1.5e-02	1.9e-02
2	Brain	gene expression	Tmeff2	0.09	0.06	2.4e-07	0.04	0.05	0.05	0.04	1.7e-04	3.7e-05	3.8e-05	2.0e-04
3	PL	gene expression	Tmeff2	0.23	0.12	7.9e-07	0.03	0.05	0.06	0.04	5.2e-04	3.8e-06	7.4e-07	7.4e-05
4	IL	mRNA stability	Tmeff2	0.21	0.12	7.0e-04	-0	0.07	0.12	0.05	3.4e-01	7.3e-03	8.9e-04	2.9e-02
5	Brain	mRNA stability	Tmeff2	0.47	0.12	0.0e+00	0.18	0.22	0.22	0.21	1.5e-16	3.6e-20	6.6e-20	2.1e-19
6	Adipose	mRNA stability	Tmeff2	0.54	0.11	1.1e-09	0.1	0.11	0.12	0.1	3.4e-11	6.1e-12	1.5e-13	2.3e-11
7	pVTA	mRNA stability	Tmeff2	0.15	0.09	2.4e-05	0.07	0.11	0.11	0.12	4.5e-04	2.4e-05	2.0e-05	6.7e-06
8	OFC	mRNA stability	Tmeff2	0.55	0.15	8.4e-09	0.16	0.27	0.18	0.28	1.6e-04	3.1e-07	3.7e-05	1.9e-07
9	Liver	gene expression	Tmeff2	0.16	0.13	4.2e-03	0.03	0.01	0.03	0.03	1.8e-04	3.9e-02	1.2e-04	2.8e-04
10	PL	mRNA stability	Tmeff2	0.06	0.04	1.7e-05	0.05	0.04	0.04	0.04	3.4e-06	1.0e-05	2.4e-05	2.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	1.1	1.8	3.8	1.7	1.7	-1.6	-1.4	1.8	-1.9	0.6	0.6	0.0	0.1
Area under the delay curve	2.0	2.1	7.1	-1.2	-1.2	1.0	1.4	-0.5	-0.6	-1.8	-1.6	2.7	1.3
BMI with tail	4.6	14.8	22.3	-4.6	-4.7	4.7	3.9	-4.5	2.3	-3.9	-3.8	2.6	2.4
BMI without tail	1.3	2.7	4.2	-1.7	-1.8	2.0	1.1	-2.0	0.8	-2.0	-2.0	0.7	1.6
Body weight	0.1	0.6	1.2	1.1	1.0	-0.9	-0.8	0.5	-0.6	0.1	0.2	-1.1	0.2
Weight adjusted by age	0.3	0.3	1.0	0.4	0.3	-0.1	0.5	-0.1	-0.3	-0.8	-0.8	-0.8	1.0
Bone surface	1.5	2.6	7.6	1.8	1.8	-2.0	-1.0	2.3	-2.8	0.6	0.7	1.2	0.1
Bone volume	1.5	2.6	7.4	2.0	2.0	-1.9	-1.4	2.1	-2.7	0.4	0.5	0.6	0.4
Breakpoint value in progressive ratio session	0.2	0.2	0.5	0.6	0.6	-0.7	-0.7	0.3	-0.1	0.2	0.2	-0.3	-0.0
Number of licking bursts	0.0	0.0	0.1	-0.1	-0.1	0.3	-0.3	-0.4	0.0	0.2	0.1	0.2	-0.1
Context. condit. distance diff. score	2.1	2.5	3.9	-2.0	-2.0	2.0	1.4	-1.8	1.8	-1.3	-1.4	1.3	0.6
Locomotion velocity, session 1	2.1	2.2	4.0	-1.7	-1.8	1.8	2.0	-1.9	1.8	-1.0	-1.1	0.2	0.4
Locomotion distance, session 1	1.0	1.3	2.5	-1.4	-1.4	1.4	1.6	-1.4	1.1	-0.9	-1.0	0.0	0.4
Locomotion velocity, session 2	2.0	2.3	5.0	-2.1	-2.0	1.7	2.2	-1.5	1.8	-0.5	-0.5	0.9	-0.4
Locomotion distance, session 2	0.2	0.3	0.9	-0.3	-0.2	0.0	0.9	-0.4	0.6	0.4	0.4	-0.9	-0.6
Locomotion velocity, session 3	2.1	2.4	5.4	0.5	0.8	-0.8	-1.9	1.5	-0.6	2.2	2.3	0.7	-2.3
Locomotion distance, session 3	0.5	0.6	1.3	0.4	0.5	-0.6	-1.1	0.7	-0.2	1.0	1.1	0.1	-1.0
Stereotopy head waving bouts, day 3	0.8	0.9	3.0	-0.0	0.1	-0.3	-0.9	0.5	0.4	1.5	1.6	0.5	-1.7
Stereotopy head waving duration, day 3	0.8	0.9	2.6	0.3	0.4	-0.4	-1.0	0.7	0.1	1.5	1.5	-0.1	-1.6
Locomotion velocity, session 7	3.1	3.4	5.7	-2.2	-2.2	2.4	2.1	-2.2	1.7	-1.5	-1.6	1.2	0.7
Locomotion distance, session 7	1.6	2.0	4.7	-1.4	-1.5	1.4	2.2	-1.8	1.5	-1.2	-1.3	0.6	0.7
Stereotopy head waving bouts, day 7	0.6	0.7	1.3	0.6	0.7	-0.6	-1.1	0.7	-0.1	1.1	1.1	-0.7	-1.0
Stereotopy head waving duration, day 7	0.6	0.7	2.9	0.4	0.4	-0.0	-1.7	0.5	-0.2	1.1	1.0	-0.8	-1.1
Locomotion velocity, session 8	1.7	2.0	4.0	-1.5	-1.6	1.6	2.0	-1.3	0.9	-1.4	-1.4	1.2	0.8
Locomotion distance, session 8	2.3	3.4	5.0	-2.2	-2.2	2.2	2.2	-2.2	2.0	-1.5	-1.6	0.7	0.7
Degree of sensitization distance	1.9	1.9	4.5	-0.9	-1.1	1.2	2.1	-1.5	0.9	-1.6	-1.7	-0.1	1.4
Degree of sensitization stereotypy	0.1	0.1	0.2	0.2	0.2	-0.2	-0.4	0.3	-0.4	0.3	0.2	-0.1	-0.1
Conditioned locomotion	2.6	3.1	5.8	2.4	2.4	-2.4	-1.5	1.8	-1.0	1.3	1.3	-1.9	-0.4
Cocaine response after cond. corrected	0.4	0.4	0.8	0.9	0.8	-0.9	0.6	0.2	-0.4	-0.4	-0.4	-0.8	0.8
Cocaine response after cond. not corrected	0.4	0.5	1.6	1.1	1.0	-0.9	-0.3	0.4	-0.3	0.2	0.1	-1.2	0.2
Cocaine response before conditioning	0.4	0.5	2.1	-0.0	0.1	0.4	-1.5	0.4	0.1	0.9	0.9	0.0	-1.0
Saline control response	0.1	0.2	0.8	-0.4	-0.3	0.5	-0.4	-0.3	0.9	0.2	0.3	-0.1	-0.5
Bone: connectivity density	0.4	0.6	2.2	0.7	0.8	-0.9	0.0	1.0	-1.5	0.1	0.1	0.8	0.2
Bone: cortical apparent density	4.8	6.4	12.9	-3.6	-3.5	3.2	2.5	-3.1	3.0	-0.8	-0.8	1.6	-0.6
Bone: cortical area	0.4	0.5	0.9	0.6	0.7	-0.8	-0.9	0.7	-0.5	0.9	0.9	-0.0	-0.7
Bone: cortical porosity	4.7	5.2	9.0	2.8	2.9	-2.9	-2.7	3.0	-2.7	1.1	1.4	-0.5	-0.1
Bone: cortical porosity	5.5	6.0	11.4	3.0	3.0	-3.0	-2.6	3.4	-3.3	1.2	1.5	-0.0	-0.1
Bone: cortical thickness	0.3	0.4	0.7	-0.9	-0.7	0.4	0.5	-0.6	0.8	0.5	0.4	0.6	-0.8
Bone: cortical thickness	0.2	0.2	0.5	-0.6	-0.6	0.6	0.2	-0.7	0.5	-0.3	-0.3	-0.1	0.1
Bone: cortical tissue density	4.9	6.4	12.9	-3.6	-3.5	3.2	2.5	-3.1	2.9	-0.9	-0.9	1.7	-0.6
Condit. Reinf. active minus inactive responses	3.5	4.0	8.5	2.2	2.2	-1.8	-2.9	2.4	-1.8	1.8	1.8	-1.1	-1.1
Condit. Reinf. active-inactive response ratio	2.2	2.3	4.5	1.7	1.7	-1.4	-2.1	1.7	-1.0	1.5	1.4	-1.6	-0.9
Condit. Reinf. active responses	2.0	2.5	4.9	1.8	1.8	-1.4	-2.1	2.2	-2.2	1.0	1.0	-0.1	-0.3
Condit. Reinf. inactive responses	0.3	0.4	1.8	-0.2	-0.2	0.2	0.2	0.2	-0.7	-0.6	-0.6	1.3	0.6
Incentive salience index mean	1.6	2.0	5.1	1.7	1.7	-1.4	-1.6	2.0	-2.2	0.5	0.6	0.0	0.2
Condit. Reinf. lever presses	0.8	1.0	3.8	0.5	0.5	-0.5	0.5	1.0	-2.0	-0.8	-0.8	1.3	1.2
Condit. Reinf. active minus inactive responses	2.2	2.7	6.1	2.5	2.4	-2.3	-1.4	1.9	-1.4	0.5	0.5	-1.1	0.5
Condit. Reinf. active-inactive response ratio	1.7	1.8	3.8	2.0	1.9	-1.7	-1.3	1.6	-1.6	0.1	0.2	-0.7	0.7
Condit. Reinf. active responses	0.4	0.6	1.4	1.2	1.1	-1.1	-0.2	0.5	0.1	-0.2	-0.3	-0.9	0.8
Condit. Reinf. inactive responses	1.3	1.6	3.5	-1.3	-1.3	1.3	1.3	-1.6	1.9	-1.1	-1.2	0.1	0.8
Condit. Reinf. lever presses	0.3	0.5	1.5	-0.5	-0.5	0.3	0.5	-0.4	0.5	-0.9	-0.8	1.2	0.8
Condit. Reinf. lever reinforcers received	0.4	0.5	1.3	1.1	1.0	-1.1	-0.0	0.5	-0.1	-0.4	-0.4	-0.6	1.0
Conditioned reinforcement - actives	0.9	0.9	2.6	0.5	0.6	-0.5	-1.1	1.0	-0.2	1.3	1.3	0.2	-1.6
Conditioned reinforcement - inactives	3.2	3.6	7.6	1.1	1.3	-1.5	-2.3	1.8	-0.6	2.6	2.8	0.3	-2.7
Conditioned locomotion	1.1	1.3	2.8	-1.6	-1.4	1.4	0.7	-1.1	1.7	-0.3	-0.2	1.1	-0.8
Patch foraging indifference point 0 sec	3.9	6.3	12.4	-2.1	-2.2	1.7	3.5	-1.8	0.7	-3.3	-3.0	2.6	2.7
Patch foraging indifference point AUC	0.5	0.6	0.9	-0.7	-0.8	0.6	0.9	-0.8	0.8	-1.0	-1.0	0.4	0.9
Delay disc. indifference point, 0s delay	2.5	2.7	5.3	-1.8	-1.8	1.8	1.5	-1.2	0.2	-2.0	-1.8	2.3	1.2
Delay disc. indifference point, 16s delay	1.6	1.6	5.7	-1.0	-1.0	1.0	0.9	-0.4	-0.7	-1.6	-1.4	2.4	1.1
Delay disc. indifference point, 2s delay	1.2	1.3	3.1	-0.7	-0.8	0.7	1.3	-0.8	0.1	-1.8	-1.6	1.1	1.5
Delay disc. indifference point, 24s delay	0.3	0.3	1.5	-0.5	-0.4	0.5	-0.1	0.1	-0.4	-0.2	-0.0	1.2	-0.2
Delay disc. indifference point, 4s delay	1.4	1.4	3.2	-1.5	-1.5	1.5	1.0	-1.0	0.5	-1.1	-0.9	1.8	0.4
Delay disc. indifference point, 8s delay	1.5	1.5	3.3	-0.5	-0.6	0.5	1.1	-0.2	-1.0	-1.8	-1.6	1.8	1.8
Indifference point function ln k	1.4	1.9	3.4	-1.2	-1.3	1.3	1.6	-1.0	-0.3	-1.8	-1.7	1.7	1.4
Indifference point function log k	1.4	1.9	3.4	-1.2	-1.3	1.3	1.6	-1.0	-0.3	-1.8	-1.7	1.7	1.4
Patch foraging total patch changes 0 sec	3.8	6.1	11.3	-2.2	-2.3	1.8	3.4	-1.9	0.8	-3.3	-2.9	2.6	2.5
Patch foraging total patch changes 12 sec	1.0	1.3	2.7	-0.9	-0.9	0.7	1.6	-0.9	0.8	-1.6	-1.4	1.0	1.3
Patch foraging total patch changes 18 sec	2.7	3.4	5.3	-2.3	-2.3	2.2	2.1	-2.1	2.0	-1.6	-1.5	1.0	0.6
Patch foraging total patch changes 24 sec	0.8	1.0	2.7	-0.9	-0.8	0.4	1.6	-0.4	0.3	-1.2	-1.0	1.5	0.8
Patch foraging total patch changes 6 sec	2.7	4.1	8.9	-1.8	-1.9	1.3	3.0	-1.4	0.4	-2.6	-2.3	2.2	2.0
Patch foraging time to switch 0 sec	1.8	2.8	5.7	1.2	1.3	-1.1	-1.4	1.0	0.3	2.4	2.2	-2.2	-2.2
Patch foraging water rate 0 sec	0.9	1.5	3.2	-0.9	-1.0	0.8	1.3	-1.0	0.7	-1.8	-1.5	1.4	1.4
Patch foraging water rate 12 sec	1.5	2.4	5.0	-1.1	-1.3	1.2	1.9	-1.5	0.4	-2.2	-2.2	0.4	1.9
Patch foraging water rate 18 sec	0.2	0.2	0.9	0.2	0.1	0.1	0.1	-0.2	0.1	-0.8	-0.8	-0.1	1.0
Patch foraging water rate 24 sec	0.2	0.2	1.3	0.3	0.2	-0.1	-0.4	-0.2	0.7	-0.1	-0.2	-1.2	0.3
Patch foraging water rate 6 sec	0.8	1.1	2.2	-0.9	-0.9	0.7	1.5	-0.8	-0.0	-1.3	-1.4	1.2	1.3
Seeking ratio, delayed vs. immediate footshock	1.4	1.6	2.5	1.6	1.6	-1.5	-1.2	1.2	-0.7	1.1	1.0	-1.6	-0.4
Distance traveled before self-admin	2.1	2.2	4.3	2.0	1.9	-1.5	-2.1	1.6	-1.9	0.5	0.6	-1.2	0.1
Distance traveled after self-admin	0.4	0.4	1.1	-0.0	-0.1	0.3	-0.5	-0.0	-0.9	-1.0	-0.8	0.8	1.0
Extensor digitorum longus weight	1.8	6.9	13.0	-3.6	-3.5	3.4	2.2	-3.4	3.6	-1.1	-1.1	0.9	-0.3
Bone: elastic displacement	0.1	0.1	0.2	0.4	0.4	-0.4	-0.2	0.3	-0.2	0.3	0.2	0.0	-0.2
Bone: elastic work	1.1	1.4	2.8	1.7	1.6	-1.5	-1.1	1.3	-1.4	0.8	0.7	-0.8	-0.1
Bone: endosteal estimation	2.2	4.9	9.3	3.0	2.9	-2.5	-2.5	2.7	-3.1	0.5	0.6	-0.8	0.6
Bone: endosteal perimeter	1.8	3.7	6.8	2.5	2.4	-2.2	-2.6	2.2	-2.3	0.9	1.1	-0.7	-0.1
Epididymis fat weight	0.4	0.9	2.0	1.2	1.0	-0.8	-1.1	0.6	-1.4	-0.6	-0.5	-0.6	1.3
Delta time in closed arm before/after self-admin	0.7	0.6	1.8	0.3	0.4	-0.6	-0.2	1.1	-1.2	0.5	0.7	1.3	-0.7
Delta time in open arm before/after self-admin	2.8	2.7	6.1	2.3	2.2	-2.1	-0.9	1.6	-1.5	0.8	0.7	-2.5	0.2
Diff in mean of infusions in LGA sessions	0.7	0.8	1.6	0.9	1.0	-0.9	-1.3	1.1	-1.2	0.4	0.6	0.3	-0.3
Delay discount exponential model param	1.7	1.8	5.6	1.0	1.1	-0.9	-1.3	0.5	0.6	1.7	1.5	-2.4	-1.3
Extinction: sum of active levers before priming	0.3	0.3	1.2	0.7	0.7	-0.7	-1.1	0.4	-0.2	0.3	0.4	-0.5	-0.2
Active lever presses in extinction session 6	0.2	0.1	0.4	0.5	0.5	-0.6	-0.2	0.2	-0.3	-0.2	-0.2	-0.4	0.4
Bone: final force	2.3	3.7	6.2	2.2	2.3	-2.1	-2.5	2.2	-2.1	1.6	1.6	-0.9	-0.8
Bone: final moment	1.7	2.7	4.7	1.9	1.9	-1.8	-2.2	1.8	-1.7	1.4	1.4	-0.9	-0.7
Food consumed during 24 hour testing period	0.3	0.4	1.3	-0.8	-0.8	1.2	-0.1	-0.7	0.6	-0.2	-0.3	0.5	-0.1
Glucose	0.6	0.9	2.6	-0.6	-0.5	0.5	-0.4	-0.4	1.3	1.2	1.2	-0.4	-1.6
Heart weight	0.1	0.1	0.3	-0.3	-0.2	0.5	-0.2	-0.3	0.6	0.0	0.1	-0.2	-0.4
Delay discount hyperbolic model param	1.9	2.0	5.7	1.2	1.2	-1.0	-1.4	0.7	0.3	1.8	1.6	-2.4	-1.3
Intermittent access intake day 1-15 change	0.3	0.3	0.8	-0.8	-0.7	0.7	0.7	-0.6	0.9	-0.2	-0.2	0.3	-0.2
Intermittent access intake escalation	0.3	0.3	0.4	-0.7	-0.6	0.6	0.6	-0.5	0.6	-0.4	-0.4	0.4	0.1
Intermittent access intake escalation 2	0.1	0.1	0.3	-0.1	-0.1	0.1	0.5	-0.1	-0.2	-0.5	-0.5	0.2	0.6
Intermitt. access day 1 inactive lever presses	2.0	2.1	6.9	-0.1	0.2	-0.2	-1.4	0.7	0.5	2.4	2.4	-0.0	-2.6
Intermitt. access day 15 inactive lever presses	0.4	0.4	1.1	0.2	0.3	-0.3	-1.0	0.6	-0.6	0.7	0.9	0.8	-0.7
Intermitt. access escalation Index	0.5	0.5	2.5	0.0	-0.0	0.1	0.0	-0.6	1.1	0.6	0.3	-1.6	-0.2
Intermittent access day 1 total infusions	0.7	0.9	1.5	0.8	0.9	-1.1	-0.8	1.1	-0.5	1.1	1.2	0.3	-1.1
Intermittent access day 15 total infusions	0.6	0.7	2.3	0.2	0.3	-0.6	-0.5	0.6	0.3	1.3	1.3	0.3	-1.5
Intermittent access terminal intake (last 3 days)	0.5	0.5	1.6	0.1	0.2	-0.5	-0.1	0.7	-0.1	1.0	1.1	0.9	-1.3
Intermittent access total infusions	1.1	1.3	2.6	0.8	1.0	-1.2	-0.8	1.2	-0.3	1.5	1.6	0.1	-1.6
Intermittent access day 1 locomotion	0.2	0.2	0.8	-0.5	-0.5	0.4	0.2	-0.2	0.4	-0.1	0.1	0.9	-0.6
Intermittent access day 15 total locomotion	0.2	0.2	1.3	-0.5	-0.4	0.4	-0.1	-0.2	0.3	-0.1	0.1	1.1	-0.5
Intermittent access total locomotion	0.3	0.4	1.6	-0.7	-0.6	0.6	0.2	-0.3	0.6	-0.1	0.2	1.3	-0.7
Intermittent access standard deviation	0.6	0.6	1.6	-0.7	-0.6	0.4	-0.2	-0.3	1.2	0.8	0.8	0.6	-1.3
Left kidney weight	0.1	0.4	0.9	0.7	0.7	-0.5	-0.9	0.3	-0.6	0.4	0.4	-0.9	0.1
Right kidney weight	0.1	0.4	1.0	-0.4	-0.5	0.6	0.5	-0.7	0.2	-0.9	-0.9	0.1	1.0
Cocaine induced anxiety	1.3	1.5	2.5	-1.2	-1.3	1.1	1.6	-1.6	1.5	-1.0	-1.1	-0.0	0.9
Post-drug Anxiety	0.1	0.1	0.2	-0.2	-0.3	0.3	0.1	-0.5	0.4	-0.3	-0.3	-0.5	0.2
Baseline Anxiety	1.6	1.7	2.7	1.6	1.6	-1.3	-1.6	1.4	-1.1	1.1	0.9	-1.3	-0.7
Tail length	4.9	14.9	27.0	5.2	5.1	-5.0	-4.0	4.3	-3.1	2.7	2.6	-3.5	-0.8
Length with tail	5.5	20.2	34.1	5.8	5.8	-5.8	-4.5	5.0	-3.1	3.7	3.7	-3.9	-1.8
Length without tail	0.7	1.5	2.9	1.5	1.5	-1.7	-0.8	1.2	-0.2	1.3	1.4	-1.2	-0.9
Times rat made contact with spout	1.6	1.9	4.5	0.6	0.8	-0.8	-1.5	1.2	-0.4	2.1	2.1	0.3	-2.1
Lifetime Intake	0.8	0.9	2.3	0.6	0.7	-1.0	-0.6	1.0	-0.0	1.3	1.4	0.1	-1.5
Liver weight, left	0.4	0.6	1.5	0.6	0.5	-0.6	0.2	0.7	-1.2	-0.7	-0.6	1.0	1.0
Liver weight, right	0.2	0.4	1.6	0.9	0.9	-1.3	0.3	0.4	-0.3	0.1	0.1	-0.6	0.5
Locomotor activity	0.4	0.7	3.5	-0.7	-0.7	0.9	-0.2	-0.3	-0.0	-0.8	-0.6	1.9	0.6
Locomotor testing distance	1.2	2.0	3.8	-1.1	-1.2	1.5	0.8	-1.1	0.2	-2.0	-1.9	1.5	1.9
Locomotor testing rearing	0.5	0.8	1.3	-0.9	-1.0	1.1	0.4	-1.0	0.6	-0.9	-1.0	0.7	1.1
Locomotion in novel chamber	2.2	2.8	6.1	-1.6	-1.7	1.9	1.1	-2.5	2.5	-1.2	-1.4	-1.0	0.8
Locomotion in novel chamber post-restriction	0.3	0.3	1.2	-0.2	-0.1	0.2	-0.2	-0.0	0.8	0.7	0.7	-0.6	-1.1
Fecal boli incidents, locomotor time 1	4.2	4.6	11.9	-0.8	-1.1	0.8	2.5	-1.1	-0.8	-3.4	-3.3	1.7	3.3
Change in fecal boli incidents, locomotor task	0.3	0.3	2.1	0.5	0.5	-0.2	-0.2	0.1	-0.2	0.1	-0.0	-1.5	0.2
Time >=10cm from walls, locomotor time 1	0.4	0.4	1.4	0.6	0.5	-0.6	0.5	0.5	-1.2	-0.6	-0.6	0.1	1.0
Bouts of movement, locomotor time 1	1.5	1.7	4.6	-0.7	-0.8	0.3	2.2	-0.9	0.3	-1.7	-1.7	1.0	1.6
Total resting periods, locomotor time 1	2.0	2.2	5.4	-1.2	-1.3	0.8	2.3	-1.3	0.5	-1.9	-1.9	1.2	1.6
Rest time, locomotor task time 1	0.3	0.3	1.0	-0.6	-0.6	0.4	1.0	-0.1	-0.2	-0.5	-0.5	0.9	0.2
Distance moved, locomotor task time 1	0.4	0.4	0.8	0.9	0.9	-0.9	-0.8	0.5	-0.2	0.6	0.5	-0.5	-0.1
Vertical activity count, locomotor time 1	0.4	0.4	0.9	0.1	0.2	0.0	-0.9	-0.1	0.7	1.0	0.9	-0.2	-0.9
Time >=10cm from walls, locomotor time 2	1.4	1.5	3.0	1.7	1.6	-1.4	-0.6	1.1	-1.7	-0.3	-0.3	-1.3	1.2
Bouts of movement, locomotor time 2	2.6	2.8	4.7	-1.9	-2.0	1.7	2.2	-2.1	2.0	-1.2	-1.4	0.7	1.0
Total resting periods, locomotor time 2	3.0	3.2	5.5	-2.1	-2.1	1.8	2.3	-2.2	2.1	-1.3	-1.5	0.9	1.0
Rest time, locomotor task time 2	0.2	0.2	0.4	-0.6	-0.5	0.4	0.6	-0.1	0.4	0.3	0.3	0.2	-0.7
Distance moved, locomotor task time 2	0.2	0.2	0.7	0.6	0.5	-0.5	-0.2	0.1	-0.3	-0.2	-0.3	-0.5	0.8
Vertical activity count, locomotor time 2	0.2	0.2	0.6	-0.4	-0.4	0.5	-0.2	-0.5	0.8	0.3	0.3	-0.3	-0.3
Light reinforcement 1	0.6	1.1	2.9	-1.6	-1.4	1.1	0.9	-0.6	0.7	0.2	0.3	1.7	-0.9
Light reinforcement 2	0.5	0.7	1.9	0.4	0.6	-0.8	-0.2	1.1	-1.4	0.6	0.7	1.0	-0.5
Bone: marrow area	2.1	4.6	8.8	2.9	2.8	-2.4	-2.5	2.7	-3.0	0.5	0.6	-0.8	0.6
Bone: maximum diameter	0.5	0.9	2.1	1.0	1.0	-1.0	-1.4	1.0	-1.1	0.7	0.7	-0.3	-0.3
Bone: maximum force	2.0	3.5	6.1	2.5	2.4	-2.3	-2.1	2.1	-1.9	1.2	1.2	-1.6	-0.3
Bone: maximum moment	1.5	2.7	4.6	2.2	2.1	-2.0	-1.8	1.7	-1.5	1.1	1.1	-1.6	-0.3
Mean time between licks in bursts	0.5	0.7	1.6	-1.1	-1.0	0.8	1.0	-1.3	1.1	-0.0	-0.1	-0.1	-0.5
Mean num. licks in bursts	0.2	0.2	0.5	0.1	0.2	-0.5	-0.1	0.7	-0.2	0.6	0.6	0.3	-0.7
Cd content in liver	0.4	0.4	1.2	0.0	0.1	-0.2	-0.7	0.2	0.8	1.0	1.0	-0.2	-1.1
Co content in liver	0.5	0.6	2.0	-0.7	-0.7	0.6	0.7	-0.3	-0.2	-1.0	-0.9	1.4	0.8
Cu content in liver	0.3	0.4	1.4	0.6	0.5	-0.3	-0.2	0.5	-1.2	-0.5	-0.5	-0.5	0.9
Fe content in liver	2.7	3.2	5.3	1.9	2.0	-1.8	-2.1	2.1	-2.3	1.7	1.7	0.0	-1.1
K content in liver	0.5	0.5	2.2	0.1	0.2	-0.7	0.5	0.7	-1.1	0.3	0.5	1.5	-0.3
Mg content in liver	0.5	0.5	1.1	0.6	0.7	-1.0	-0.2	0.8	-0.5	1.0	1.0	0.2	-0.8
Mn content in liver	1.0	1.2	2.4	-1.4	-1.4	1.4	0.7	-1.5	1.3	-0.5	-0.5	0.8	-0.1
Na content in liver	1.1	1.2	2.6	-0.4	-0.5	0.1	1.3	-0.2	-1.2	-1.4	-1.3	1.6	1.4
Rb content in liver	0.1	0.2	0.8	0.0	-0.0	-0.2	0.9	-0.3	0.6	0.2	0.0	-0.7	-0.0
Se content in liver	0.1	0.1	0.4	0.2	0.3	-0.2	-0.3	-0.1	0.0	0.5	0.5	-0.1	-0.7
Sr content in liver	0.3	0.3	1.1	0.1	0.2	-0.3	-0.2	0.4	0.1	0.8	0.9	0.1	-1.1
Zn content in liver	0.1	0.1	0.8	-0.3	-0.2	0.1	-0.1	0.1	0.2	0.0	0.1	0.9	-0.3
Bone: minimum diameter	0.8	1.4	2.5	1.5	1.5	-1.4	-1.5	1.6	-1.3	0.7	0.8	-0.3	-0.2
Time in familiar zone, hab. session 1	0.5	0.5	0.8	-0.9	-0.9	0.8	0.6	-0.8	0.9	-0.4	-0.4	0.7	0.0
Time in novel zone, hab. session 1	1.4	1.3	2.7	1.6	1.5	-1.2	-1.2	1.3	-1.6	0.1	0.1	-0.8	0.5
Total zone transitions, hab. session 1	0.2	0.3	1.0	-0.2	-0.2	0.3	0.1	0.0	-0.6	-0.7	-0.6	1.0	0.7
Total locomotion distance, hab. session 1	0.2	0.3	0.7	0.8	0.7	-0.6	-0.6	0.5	-0.8	-0.2	-0.1	-0.2	0.5
Locomotion velocity, hab. session 1	0.3	0.4	0.8	0.8	0.8	-0.9	-0.5	0.7	-0.8	0.2	0.3	0.0	0.1
Time in familiar zone, hab. session 2	0.5	0.5	1.3	-0.2	-0.3	0.6	0.5	-0.7	0.4	-1.1	-1.2	-0.2	1.1
Time in novel zone, hab. session 2	1.0	1.0	2.1	0.7	0.8	-1.0	-0.8	0.9	-0.3	1.5	1.4	-0.4	-1.3
Total zone transitions, hab. session 2	0.0	0.0	0.1	-0.2	-0.2	-0.0	0.2	-0.2	0.3	0.1	0.0	-0.1	-0.1
Total locomotion distance, hab. session 2	0.8	1.0	1.7	1.0	1.0	-1.1	-1.3	0.8	-0.2	1.1	1.1	-1.2	-0.9
Locomotion velocity, hab. session 2	0.5	0.6	1.5	0.7	0.7	-0.8	-1.0	0.5	0.2	0.9	0.9	-1.2	-0.7
Novel to familiar place preference ratio	5.3	5.5	9.2	2.8	2.9	-3.0	-1.8	2.7	-1.9	2.3	2.3	-1.5	-1.4
Novelty place preference	5.5	5.6	9.2	2.7	2.8	-3.0	-1.8	2.7	-1.8	2.5	2.5	-1.4	-1.6
Time in novel zone, NPP test	6.4	6.6	10.6	2.9	3.0	-3.3	-2.0	3.0	-2.0	2.8	2.8	-1.5	-1.9
Total zone transitions, NPP test	0.3	0.4	0.8	-0.8	-0.8	0.6	0.8	-0.9	0.9	-0.5	-0.5	-0.2	0.2
Total locomotion distance, NPP test	0.1	0.2	0.9	0.3	0.2	-0.3	-0.1	-0.2	0.3	-0.2	-0.2	-1.0	0.4
Locomotion velocity, NPP test	0.1	0.1	0.4	-0.1	-0.2	0.1	0.1	-0.4	0.6	-0.4	-0.4	-0.6	0.4
Intraocular pressure	1.5	2.1	5.2	-1.5	-1.6	1.9	0.9	-2.1	2.3	-0.4	-0.7	-1.2	-0.1
Delta distance traveled before/after self-admin	1.1	1.2	2.0	-1.4	-1.4	1.3	1.1	-1.4	1.3	-0.7	-0.8	0.6	0.4
Delta ambulatory time before/after self-admin	1.8	2.0	2.7	-1.6	-1.6	1.5	1.6	-1.6	1.2	-1.4	-1.4	1.0	1.0
Parametrial fat weight	0.1	0.2	0.8	-0.3	-0.3	0.6	0.0	-0.6	0.9	-0.2	-0.1	-0.8	0.2
Pavlov. Cond. lever latency	0.8	1.0	4.1	-0.4	-0.2	-0.0	-0.1	-0.1	1.1	1.5	1.5	0.1	-2.0
Pavlov. Cond. magazine entry latency	0.7	1.0	3.3	0.7	0.5	-0.2	-0.2	-0.0	-0.6	-1.3	-1.3	-1.3	1.8
Pavlov. Cond. change in total contacts	0.4	0.5	1.8	0.3	0.1	0.0	0.0	-0.2	-0.3	-0.9	-1.0	-0.8	1.3
Pavlov. Cond. index score	0.8	1.0	4.0	0.6	0.4	-0.2	-0.0	0.0	-0.8	-1.4	-1.5	-0.9	2.0
Pavlov. Cond. latency score	1.1	1.4	5.5	0.6	0.4	-0.1	0.1	-0.1	-0.8	-1.7	-1.8	-0.8	2.4
Pavlov. Cond. lever contacts	0.6	0.7	2.9	0.3	0.2	-0.0	0.2	-0.0	-0.8	-1.3	-1.3	-0.1	1.7
Pavlov. Cond. magazine entry number	0.8	1.0	2.5	-1.2	-1.0	0.6	1.0	-0.5	1.0	0.6	0.6	1.6	-1.3
Pavlov. Cond. intertrial magazine entries	2.7	3.2	5.6	1.4	1.6	-1.6	-1.9	2.0	-1.3	2.3	2.4	0.6	-2.1
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	3.4	0.5	0.3	-0.1	-0.0	-0.1	-0.6	-1.3	-1.4	-0.9	1.8
Pavlov. Cond. response bias	0.5	0.6	1.8	0.8	0.6	-0.5	-0.3	0.2	-0.7	-0.8	-0.8	-0.9	1.3
Pavlov. Cond. lever latency	0.5	0.6	1.1	0.7	0.7	-0.7	-0.8	0.6	-0.4	1.1	1.0	-0.8	-1.0
Pavlov. Cond. magazine entry latency	0.2	0.2	0.7	-0.5	-0.4	0.4	-0.4	0.1	-0.2	0.4	0.5	0.8	-0.7
Pavlov. Cond. change in total contacts	0.4	0.6	1.3	0.5	0.4	-0.5	0.5	0.5	-1.1	-0.9	-0.8	0.8	1.2
Pavlov. Cond. index score	0.1	0.1	0.4	-0.3	-0.3	0.2	0.2	-0.1	-0.2	-0.5	-0.4	0.7	0.4
Pavlov. Cond. latency score	0.1	0.1	0.3	-0.1	-0.1	0.1	0.0	0.1	-0.3	-0.3	-0.2	0.6	0.3
Pavlov. Cond. lever contacts	0.4	0.6	1.4	-0.4	-0.5	0.4	0.6	-0.3	-0.1	-1.2	-1.1	0.9	1.2
Pavlov. Cond. magazine entry number	0.3	0.4	0.8	-0.5	-0.5	0.6	0.6	-0.9	0.8	-0.6	-0.7	-0.4	0.6
Pavlov. Cond. intertrial magazine entries	0.3	0.4	1.8	-0.5	-0.5	0.6	0.1	-0.8	1.4	0.1	0.0	-0.8	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.4	-0.3	-0.3	0.2	0.2	-0.1	-0.1	-0.4	-0.3	0.6	0.3
Pavlov. Cond. response bias	0.1	0.1	0.6	-0.0	-0.0	-0.0	-0.0	0.2	-0.3	-0.4	-0.3	0.8	0.4
Time in closed arm before self-admin	1.2	1.3	2.8	1.7	1.5	-1.5	-0.6	1.1	-1.3	-0.3	-0.4	-1.1	1.1
Time in closed arm after self-admin	1.3	1.3	4.1	0.8	0.7	-0.9	0.4	1.1	-2.0	-1.0	-0.9	1.3	1.4
Time in open arm before self-admin	1.6	1.7	4.2	-1.6	-1.4	1.4	0.1	-1.2	2.0	0.8	0.8	0.6	-1.8
Time in open arm after self-admin	1.5	1.7	3.6	1.5	1.5	-1.3	-1.4	1.0	-0.5	1.3	1.2	-1.9	-0.8
Bone: periosteal estimation	2.0	4.0	6.7	2.6	2.5	-2.4	-2.5	2.5	-2.5	1.0	1.1	-0.4	-0.1
Bone: periosteal perimeter	1.6	2.7	4.7	2.1	2.1	-2.1	-2.2	1.8	-1.5	1.2	1.3	-0.8	-0.5
Bone: post-yield work	0.8	1.0	1.9	1.3	1.3	-1.1	-1.4	1.2	-1.0	0.7	0.8	-0.6	-0.3
Progressive ratio test 1 active lever presses	0.2	0.2	0.9	-0.1	-0.0	-0.3	0.1	0.1	0.5	0.6	0.6	0.0	-0.9
Progressive ratio test 1 breakpoint	0.1	0.1	0.5	-0.2	-0.1	-0.1	0.4	-0.0	0.6	0.3	0.3	0.1	-0.7
Progressive ratio test 1 inactive lever presses	1.8	2.0	7.7	-0.7	-0.5	0.2	-0.7	0.0	1.5	2.0	2.1	0.3	-2.8
Progressive ratio test 2 active lever presses	2.0	2.1	5.1	0.8	1.0	-1.2	-1.3	1.6	-0.5	2.1	2.1	0.4	-2.3
Progressive ratio test 2 breakpoint	1.3	1.5	4.0	0.4	0.7	-0.8	-0.9	1.3	-0.5	1.7	1.7	0.8	-2.0
Progressive ratio test 2 inactive lever presses	1.8	2.1	5.4	0.6	0.8	-0.9	-1.5	1.3	-0.1	2.2	2.3	0.1	-2.3
Incentive Sensitization - Responses	1.8	1.8	3.0	1.1	1.2	-1.2	-1.5	1.5	-0.8	1.7	1.7	-0.2	-1.6
Incentive Sensitization - Breakpoint	1.9	1.9	3.5	1.0	1.2	-1.1	-1.6	1.5	-0.8	1.9	1.8	-0.1	-1.7
Sum of active levers in priming session hrs 5-6	0.9	0.8	2.6	1.2	1.1	-1.1	-1.0	0.5	-0.4	0.4	0.4	-1.6	0.1
Progressive ratio	0.3	0.3	0.9	0.1	0.1	0.2	-0.5	0.4	0.1	1.0	0.8	-0.6	-0.9
Food seeking constrained by brief footshock	1.1	1.4	2.5	1.5	1.5	-1.6	-0.4	1.5	-1.2	1.0	0.9	-1.2	-0.3
Seeking ratio, punishment vs. effort	0.2	0.2	0.7	0.4	0.3	-0.7	0.4	0.0	-0.3	-0.6	-0.5	-0.0	0.8
Retroperitoneal fat weight	0.2	0.5	1.3	-0.5	-0.6	0.7	0.6	-0.7	0.1	-1.1	-1.1	-0.1	0.8
Reaction time number correct	1.0	1.5	5.0	-0.5	-0.3	0.1	0.1	-0.4	1.7	1.8	1.6	-0.9	-2.2
Reaction time mean minus median	1.3	1.8	3.9	2.0	1.9	-1.8	-1.1	1.4	-1.6	0.2	0.1	-0.9	0.6
Reaction time mean minus median AUC	1.3	1.6	3.5	1.9	1.8	-1.7	-1.0	1.5	-1.6	0.3	0.2	-0.7	0.4
Reaction time num false alarms	2.0	2.7	6.2	-2.5	-2.3	2.3	1.4	-1.6	0.5	-0.5	-0.5	2.2	-0.3
Reaction time num false alarms AUC	1.8	2.5	5.8	-2.4	-2.2	2.2	1.1	-1.4	0.5	-0.2	-0.2	2.3	-0.6
Reaction time trials correct on left	1.0	1.5	5.0	-0.5	-0.3	0.1	0.1	-0.4	1.7	1.8	1.6	-0.9	-2.2
Reaction time trials on left	1.1	1.6	5.4	-0.4	-0.2	0.0	0.0	-0.3	1.6	1.9	1.7	-1.0	-2.3
Reaction time mean	3.9	5.5	10.4	3.1	3.0	-2.5	-3.2	2.4	-2.2	1.4	1.2	-2.3	-0.1
Reaction time mean AUC	3.6	4.9	10.0	2.9	2.8	-2.3	-3.2	2.2	-2.0	1.3	1.2	-2.3	-0.2
Median of all reaction times	3.8	5.2	11.0	2.9	2.8	-2.3	-3.3	2.2	-2.0	1.4	1.3	-2.6	-0.2
Reaction time omissions	0.8	1.1	1.6	1.3	1.3	-1.1	-1.1	1.1	-0.9	1.0	0.8	-1.2	-0.6
Reaction time false alarm rate	1.6	2.2	6.8	-1.9	-1.8	1.9	1.0	-1.0	-0.5	-1.1	-1.0	2.6	0.6
Reaction time premature initiation rate	1.3	1.8	4.6	-0.8	-0.9	1.0	0.7	-1.0	-0.3	-2.2	-1.9	1.4	1.8
Reaction time premature initiations	0.5	0.8	1.3	-1.0	-1.0	1.0	0.7	-1.1	0.8	-1.0	-0.8	0.7	0.4
Std. dev. reaction times	2.8	3.9	8.0	2.8	2.7	-2.4	-2.1	2.1	-2.3	0.7	0.5	-1.6	0.5
Reaction time trials completed	1.1	1.6	5.4	-0.4	-0.2	0.0	0.0	-0.3	1.6	1.9	1.7	-1.0	-2.3
Reaction time trials AUC	1.1	1.5	5.2	-0.4	-0.3	0.1	0.1	-0.3	1.6	1.8	1.6	-1.0	-2.3
Run reversals in cocaine runway, females	0.6	0.6	1.5	0.3	0.4	-0.4	-0.7	0.4	0.5	1.1	1.1	-0.9	-1.2
Run reversals in cocaine runway, males	0.4	0.3	1.8	-0.5	-0.5	0.3	0.4	-0.3	-0.3	-0.6	-0.4	1.3	0.5
Latency to leave start box in cocaine runway	4.2	4.5	8.6	-2.9	-2.9	2.5	2.3	-2.5	2.3	-1.1	-1.0	1.7	0.2
Latency to leave start box in cocaine runway, F	1.9	2.0	6.2	-2.0	-1.9	1.6	0.9	-1.2	0.9	-0.5	-0.3	2.5	-0.2
Latency to leave start box in cocaine runway, M	3.4	3.3	5.9	-2.0	-2.1	1.8	2.4	-2.3	2.3	-1.3	-1.4	-0.2	0.8
Std. dev. time between licks in bursts	0.9	1.0	3.6	-1.3	-1.2	0.6	1.5	-0.8	0.4	-0.2	-0.1	1.9	-0.4
Total sessions with >9 infusions	0.7	0.8	2.5	-1.0	-0.9	0.8	0.9	-0.8	1.6	-0.0	-0.0	-0.0	-1.0
Short access day 1 total inactive lever presses	0.4	0.5	1.2	0.3	0.4	-0.3	-0.9	0.4	0.1	1.0	1.1	-0.4	-1.1
Short access day 10 total inactive lever presses	1.7	1.9	4.9	0.3	0.5	-0.4	-1.8	0.9	-0.1	2.1	2.2	0.2	-2.2
Short access day 1 total infusions	0.2	0.2	1.0	-0.0	-0.0	-0.1	0.3	-0.3	1.0	0.1	0.1	-1.0	-0.5
Short access day 10 total infusions	0.6	0.7	1.4	0.7	0.8	-1.2	-0.4	0.9	-0.2	0.9	1.0	-0.0	-1.0
Short access total infusions	0.1	0.1	0.5	-0.1	-0.0	-0.2	0.3	0.1	0.5	0.3	0.4	0.1	-0.7
Short access day 1 locomotion	0.4	0.4	1.6	-0.2	-0.1	-0.1	0.0	-0.1	1.1	0.7	0.8	-0.4	-1.3
Short access day 10 total locomotion	0.8	0.9	3.4	-1.0	-1.0	0.9	0.6	-0.6	0.2	-1.0	-0.8	1.8	0.3
Short access total locomotion	0.7	0.7	2.0	-0.9	-0.8	0.7	-0.0	-0.6	1.4	0.6	0.7	0.4	-1.4
One hour access (0.3 mA shock)	0.8	1.0	2.3	0.9	1.0	-1.3	-0.3	1.5	-1.4	0.5	0.6	1.1	-0.3
Compulsive drug intake	0.5	0.5	1.7	-0.3	-0.4	0.4	0.5	-0.1	-0.7	-0.9	-0.8	1.3	1.0
One hour access (shock baseline)	1.4	1.7	2.5	1.3	1.4	-1.5	-1.0	1.4	-0.5	1.6	1.6	-0.7	-1.4
Social response proportion	1.0	1.1	2.2	1.5	1.3	-1.3	-0.2	0.8	-0.9	-0.6	-0.8	-1.2	1.3
Social responses	0.6	0.7	3.0	0.6	0.4	-0.5	0.8	-0.1	-0.2	-1.0	-1.3	-0.2	1.7
Social time	0.7	1.0	2.2	1.5	1.3	-1.2	-0.6	0.8	-1.0	0.1	-0.2	-1.4	0.8
Soleus weight	0.7	1.9	6.6	-0.6	-0.7	0.8	1.1	-1.6	2.0	-0.9	-1.2	-2.6	1.0
Bone: stiffness	1.0	1.6	2.9	1.7	1.7	-1.6	-1.4	1.5	-1.2	0.8	0.8	-1.0	-0.2
Tibialis anterior weight	0.6	2.2	4.1	-2.0	-2.0	1.7	1.4	-1.7	2.0	-0.6	-0.6	1.2	-0.2
Time to tail flick, vehicle, before self-admin	0.4	0.4	2.1	-0.7	-0.7	0.4	0.8	-0.3	-0.2	-0.4	-0.3	1.5	0.2
Time to tail flick, vehicle, after self-admin	0.5	0.6	1.4	0.5	0.6	-0.9	-0.3	1.0	-1.0	0.4	0.6	1.2	-0.5
Time to tail flick, test, before self-admin	0.5	0.5	1.7	-0.6	-0.5	0.5	-0.3	0.0	0.3	0.7	0.9	0.8	-1.3
Time to tail flick, test, after self-admin	0.9	1.0	1.8	-1.3	-1.3	1.3	1.3	-1.1	1.0	-0.5	-0.6	0.6	0.0
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.0	0.7	0.8	-0.6	-1.0	0.8	-0.2	0.9	0.9	-0.6	-0.9
Delta time to tail flick, test, before/after SA	1.4	1.3	3.1	-0.4	-0.6	0.5	1.5	-1.1	0.4	-1.5	-1.7	-0.5	1.8
Tibia length	2.7	7.5	13.3	3.6	3.6	-3.1	-3.1	3.0	-2.6	1.6	1.6	-3.0	-0.4
Ambulatory time before self-admin	1.7	1.8	4.5	1.6	1.6	-1.2	-2.1	1.3	-1.2	0.8	0.9	-1.3	-0.5
Ambulatory time after self-admin	1.6	1.7	3.7	-1.1	-1.2	1.4	0.8	-1.3	0.2	-1.9	-1.8	0.8	1.6
Bone: tissue strength	0.6	0.6	0.9	0.8	0.8	-0.7	-0.8	0.8	-0.5	0.9	0.9	-0.8	-0.7
Total heroin consumption	0.3	0.4	0.8	0.7	0.7	-0.9	-0.7	0.8	-0.9	0.2	0.3	0.5	-0.1
Bone: trabecular number	0.5	0.8	2.2	1.1	1.1	-1.0	-0.5	1.2	-1.5	0.1	0.1	0.1	0.4
Bone: trabecular spacing	0.6	0.8	1.3	-0.8	-0.9	0.8	1.1	-1.0	0.6	-1.1	-1.1	0.5	0.8
Bone: trabecular thickness	0.3	0.3	0.7	0.8	0.8	-0.7	-0.8	0.6	-0.8	0.1	0.1	-0.4	0.3
Bone: trabecular tissue density	0.4	0.6	1.6	-0.6	-0.6	0.9	-0.3	-1.0	1.2	0.1	0.1	-1.3	-0.4
Water consumed over 24 hours	0.5	0.6	1.4	-1.1	-1.1	1.1	0.1	-0.7	0.7	0.0	-0.1	1.2	-0.4
Number of responses in last shaping day	1.0	1.0	3.3	-1.0	-0.8	0.7	-0.2	-0.1	0.9	1.1	1.1	1.1	-1.8