Hub : Genes

Timp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA NM_021989.3 0.03 0.02 5.3e-05 0.02 0.01 0.02 0 5.3e-03 2.6e-02 5.0e-03 3.0e-01
2 NAcc isoform ratio NM_021989.3 0.03 0.02 5.2e-03 0.01 0.01 0.01 0.01 1.0e-02 1.4e-02 2.2e-02 1.4e-02
3 NAcc isoform ratio XM_039085773.1 0.02 0.02 9.6e-03 0.01 0.01 0.01 0.01 1.6e-02 1.7e-02 1.7e-02 2.5e-02
4 Liver isoform ratio NM_021989.3 0.04 0.03 9.1e-06 0.02 0.02 0.03 -0 1.2e-03 2.4e-03 3.9e-04 5.4e-01
5 Liver isoform ratio XM_039085773.1 0.04 0.03 6.9e-06 0.02 0.02 0.03 0 1.2e-03 1.0e-03 1.9e-04 2.4e-01
6 NAcc alternative polyA XM_039085773.1 0.02 0.02 6.5e-03 0.02 0.01 0.03 0.01 7.3e-04 1.5e-02 5.9e-04 7.1e-03
7 PL isoform ratio NM_021989.3 0.04 0.02 1.1e-04 0.03 0.03 0.03 0.03 8.3e-04 2.6e-04 8.6e-04 4.8e-04
8 Liver alternative polyA XM_039085773.1 0.03 0.02 1.3e-04 0.01 0.01 0.01 0.01 1.4e-02 6.9e-02 3.5e-02 6.0e-02
9 PL isoform ratio XM_039085773.1 0.03 0.02 2.0e-04 0.02 0.02 0.02 0.02 1.7e-03 9.9e-04 3.5e-03 2.0e-03
10 Adipose gene expression Timp2 0.25 0.1 0.0e+00 0.17 0.2 0.22 0.22 3.9e-18 9.4e-22 4.2e-24 8.6e-24
11 NAcc alternative polyA NM_021989.3 0.02 0.01 9.0e-03 0.02 0.01 0.01 0.01 9.8e-04 2.6e-02 4.3e-02 6.9e-03
12 PL alternative polyA NM_021989.3 0.07 0.06 1.7e-06 0.06 0.05 0.06 0.06 1.7e-07 2.2e-06 5.8e-07 1.9e-07
13 PL alternative polyA XM_039085773.1 0.03 0.02 6.8e-04 0.04 0.03 0.04 0.04 2.3e-05 7.1e-04 5.3e-05 5.7e-05
14 OFC gene expression Timp2 0.31 0.19 1.6e-03 0.06 0.06 0.06 0.05 1.4e-02 1.5e-02 1.9e-02 2.6e-02
15 Liver mRNA stability Timp2 0.1 0.06 6.7e-05 0.04 -0 0.04 0.04 2.8e-05 4.3e-01 8.0e-05 4.3e-05
16 IL mRNA stability Timp2 0.65 0.21 1.8e-03 0.11 0.08 0.1 0.13 1.2e-03 5.2e-03 2.2e-03 4.4e-04
17 Liver gene expression Timp2 0.18 0.08 0.0e+00 0.28 0.27 0.28 0.27 2.9e-31 5.7e-30 8.6e-31 3.0e-30
18 IL gene expression Timp2 0.67 0.13 6.4e-11 0.36 0.32 0.38 0.38 1.9e-09 2.1e-08 4.3e-10 3.9e-10
19 Adipose alternative polyA XM_039085773.1 0.16 0.08 0.0e+00 0.12 0.13 0.14 0.13 4.2e-13 2.0e-14 6.1e-15 2.1e-14
20 Adipose alternative polyA NM_021989.3 0.15 0.08 0.0e+00 0.12 0.13 0.14 0.13 2.3e-13 1.2e-14 4.0e-15 1.4e-14
21 PL gene expression Timp2 0.18 0.08 0.0e+00 0.12 0.17 0.16 0.17 9.5e-13 4.6e-18 8.2e-18 4.7e-18
22 Adipose isoform ratio NM_021989.3 0.14 0.07 1.5e-14 0.08 0.11 0.1 0.1 5.7e-09 7.8e-12 2.4e-11 4.2e-11
23 Adipose isoform ratio XM_039085773.1 0.15 0.08 3.7e-15 0.09 0.11 0.11 0.1 1.2e-09 1.6e-12 6.9e-12 1.9e-11
24 NAcc gene expression Timp2 0.21 0.1 5.2e-11 0.11 0.11 0.11 0.11 4.9e-13 2.9e-12 3.8e-13 6.6e-13
25 Brain gene expression Timp2 0.39 0.11 0.0e+00 0.3 0.32 0.32 0.32 1.8e-28 1.5e-30 6.8e-30 4.7e-30
26 Brain mRNA stability Timp2 0.07 0.04 1.5e-03 0.03 0.02 0.02 0.02 1.1e-03 2.7e-03 4.3e-03 4.9e-03
27 BLA gene expression Timp2 0.31 0.12 1.5e-08 0.16 0.15 0.15 0.15 4.7e-09 2.1e-08 1.8e-08 2.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density1.11.94.82.02.2-2.22.1-2.0-1.4-1.2-2.21.10.41.61.2-1.21.11.2-1.51.3-0.5-0.60.60.4-0.60.61.3-0.51.41.4
Area under the delay curve1.71.83.9-1.1-0.10.1-0.80.80.81.50.1-1.5-2.0-0.9-1.41.41.31.3-1.0-1.5-1.81.7-1.7-1.81.8-1.81.1-1.61.00.9
BMI with tail2.68.523.6-1.2-2.52.5-1.21.12.3-1.02.61.12.8-0.60.7-0.7-4.5-4.34.51.24.0-2.62.62.8-2.52.5-4.73.5-4.9-4.7
BMI without tail0.71.42.61.30.7-0.71.2-1.20.1-1.5-0.81.51.51.11.0-1.0-0.7-0.80.51.51.4-1.61.61.5-1.51.5-0.91.2-0.9-0.9
Body weight0.94.010.4-2.4-3.03.0-2.52.41.41.12.8-1.1-0.0-1.8-2.02.0-2.6-2.63.2-1.22.00.0-0.10.5-0.10.0-2.51.4-2.4-2.2
Weight adjusted by age0.20.20.80.20.5-0.50.4-0.40.90.3-0.7-0.3-0.6-0.1-0.50.50.70.8-0.7-0.1-0.40.4-0.4-0.40.4-0.40.5-0.70.30.3
Bone surface2.95.212.50.82.4-2.41.4-1.20.51.3-2.4-1.3-2.5-0.6-0.80.83.53.5-3.1-0.7-3.21.8-1.8-2.42.0-2.03.4-3.23.23.1
Bone volume1.72.97.11.42.5-2.51.9-1.8-0.20.2-2.5-0.2-1.30.20.2-0.22.52.7-2.40.3-2.10.7-0.7-1.20.9-0.82.5-2.12.42.4
Breakpoint value in progressive ratio session0.50.51.61.31.1-1.11.2-1.30.7-0.2-1.10.20.2-0.80.6-0.60.50.5-0.31.2-0.3-0.80.80.1-0.40.40.3-0.30.20.2
Number of licking bursts0.10.10.5-0.2-0.20.2-0.20.2-0.70.20.1-0.2-0.3-0.1-0.30.3-0.30.10.2-0.2-0.10.2-0.2-0.20.2-0.20.2-0.10.20.3
Context. condit. distance diff. score0.30.43.70.10.5-0.50.3-0.21.90.5-0.5-0.4-0.5-0.6-0.00.00.70.8-0.4-0.3-0.70.6-0.6-0.60.5-0.40.4-0.70.10.3
Locomotion velocity, session 10.91.02.4-1.5-1.41.4-1.51.5-1.11.01.3-1.0-0.9-0.5-1.41.4-0.4-0.30.4-1.3-0.21.0-1.0-0.70.9-1.0-0.1-0.3-0.00.0
Locomotion distance, session 11.72.110.41.30.4-0.40.9-1.0-3.2-1.9-0.31.91.71.71.4-1.4-1.2-1.10.61.61.6-1.71.71.8-1.71.7-0.61.6-0.3-0.2
Locomotion velocity, session 20.40.51.20.60.4-0.40.5-0.5-1.1-1.0-0.21.00.90.90.9-0.9-0.3-0.50.20.80.6-0.80.80.9-0.80.8-0.40.7-0.4-0.4
Locomotion distance, session 23.44.814.12.11.1-1.11.7-1.7-3.8-3.0-0.93.02.83.02.4-2.4-1.6-1.50.62.42.1-2.52.52.7-2.72.6-1.02.2-0.8-0.8
Locomotion velocity, session 30.30.41.9-0.8-0.60.6-0.70.7-1.40.50.5-0.5-0.60.3-0.60.60.20.2-0.2-0.8-0.40.8-0.8-0.60.7-0.70.2-0.30.20.1
Locomotion distance, session 31.11.22.7-0.2-1.21.2-0.70.6-0.4-0.71.30.71.30.50.6-0.6-1.6-1.61.40.61.6-1.01.01.2-1.01.0-1.41.6-1.2-1.3
Stereotopy head waving bouts, day 30.80.95.2-1.0-0.60.6-0.70.72.31.40.4-1.4-1.1-1.8-0.80.80.40.40.2-1.0-0.60.9-0.9-1.01.0-0.90.1-0.9-0.1-0.0
Stereotopy head waving duration, day 31.11.34.8-0.80.1-0.1-0.30.42.21.5-0.2-1.5-1.5-1.8-0.90.91.11.1-0.5-1.1-1.31.3-1.3-1.41.3-1.30.7-1.50.40.5
Locomotion velocity, session 70.50.61.40.50.9-0.90.6-0.5-0.20.1-0.9-0.2-0.70.5-0.50.51.01.0-1.2-0.1-1.00.5-0.5-0.70.6-0.61.1-0.91.11.2
Locomotion distance, session 71.82.26.22.52.1-2.12.2-2.2-0.8-1.9-2.01.81.21.91.4-1.40.40.4-1.11.90.3-1.41.41.1-1.31.30.60.40.70.7
Stereotopy head waving bouts, day 71.92.19.8-1.6-1.01.0-1.21.23.12.10.7-2.1-1.7-2.2-1.21.20.90.9-0.2-1.5-1.11.7-1.6-1.71.6-1.60.3-1.30.0-0.0
Stereotopy head waving duration, day 73.13.87.8-2.2-1.11.1-1.81.82.02.81.0-2.8-2.5-2.5-1.91.91.21.3-0.4-2.3-1.92.5-2.4-2.42.4-2.41.0-2.00.80.8
Locomotion velocity, session 81.41.63.4-0.40.6-0.6-0.00.11.21.1-0.7-1.1-1.6-0.4-1.11.11.91.8-1.4-1.1-1.81.6-1.6-1.61.6-1.51.4-1.81.11.2
Locomotion distance, session 81.52.24.42.01.7-1.71.9-1.9-1.1-2.1-1.52.11.71.71.9-1.9-0.5-0.2-0.11.80.8-1.51.51.6-1.71.7-0.21.0-0.2-0.2
Degree of sensitization distance3.73.711.52.73.4-3.43.0-2.9-0.7-1.4-3.41.40.11.81.1-1.12.12.0-2.61.4-1.2-0.50.50.0-0.30.41.9-1.11.71.9
Degree of sensitization stereotypy0.80.93.3-1.1-0.80.8-0.90.91.81.40.6-1.4-1.1-1.4-0.80.80.50.6-0.1-1.0-0.71.1-1.1-1.11.1-1.10.2-0.80.0-0.0
Conditioned locomotion0.20.30.90.80.7-0.70.8-0.8-0.9-0.5-0.70.50.30.30.6-0.60.30.2-0.40.50.1-0.50.50.3-0.40.40.40.10.60.6
Cocaine response after cond. corrected0.30.33.7-0.5-0.50.5-0.40.41.90.30.3-0.30.0-1.1-0.20.2-0.4-0.40.5-0.20.20.1-0.10.00.0-0.0-0.50.1-0.7-0.7
Cocaine response after cond. not corrected0.20.21.8-0.4-0.10.1-0.10.21.30.4-0.1-0.4-0.5-0.6-0.50.50.30.3-0.2-0.4-0.30.5-0.6-0.40.4-0.40.0-0.5-0.2-0.1
Cocaine response before conditioning1.11.43.10.41.2-1.20.6-0.5-1.50.2-1.1-0.3-1.21.1-0.70.71.61.8-1.7-0.5-1.41.1-1.0-1.11.1-1.11.6-1.41.51.6
Saline control response1.41.83.7-0.30.5-0.5-0.30.4-1.50.7-0.4-0.7-1.50.8-1.31.31.61.7-1.7-1.4-1.91.7-1.7-1.61.6-1.71.7-1.61.71.7
Bone: connectivity density1.72.76.02.22.4-2.42.1-2.0-2.0-0.9-2.40.9-0.21.90.7-0.71.91.9-2.30.9-1.3-0.10.1-0.20.0-0.02.1-1.12.32.2
Bone: cortical apparent density2.43.26.20.8-0.60.60.3-0.4-1.6-1.80.51.82.51.41.6-1.6-2.3-2.31.81.52.5-2.12.12.4-2.22.2-1.92.3-1.7-1.6
Bone: cortical area2.53.78.9-2.7-2.92.9-2.62.51.81.52.9-1.4-0.2-2.2-1.41.4-2.2-2.23.0-1.21.50.3-0.30.20.2-0.2-2.20.9-2.2-2.2
Bone: cortical porosity1.11.22.5-1.3-0.70.7-1.01.00.31.60.6-1.6-1.6-1.1-1.51.50.90.7-0.4-1.2-1.11.3-1.3-1.41.5-1.50.5-1.20.40.4
Bone: cortical porosity1.71.83.7-1.5-0.60.6-1.01.10.81.90.5-1.9-1.9-1.5-1.71.71.21.0-0.6-1.4-1.41.6-1.6-1.81.8-1.70.7-1.50.50.5
Bone: cortical thickness7.011.529.0-2.7-4.54.5-3.23.10.3-0.44.60.42.6-0.6-0.40.4-5.4-5.35.4-0.14.4-1.71.72.7-2.02.0-5.13.9-4.8-4.8
Bone: cortical thickness4.45.112.9-1.9-2.92.9-2.01.90.3-0.23.00.31.7-0.3-0.30.3-3.5-3.43.30.02.9-1.21.21.7-1.31.2-3.52.5-3.5-3.6
Bone: cortical tissue density2.33.16.20.9-0.40.40.5-0.6-1.6-1.90.31.92.51.41.7-1.7-2.2-2.21.61.62.4-2.12.12.4-2.22.2-1.82.3-1.6-1.5
Condit. Reinf. active minus inactive responses0.20.20.70.50.8-0.80.6-0.70.3-0.3-0.70.30.10.30.6-0.60.30.5-0.60.6-0.5-0.20.2-0.10.00.00.2-0.40.1-0.0
Condit. Reinf. active-inactive response ratio0.80.92.71.11.6-1.61.3-1.2-0.4-0.3-1.50.3-0.20.40.7-0.71.11.2-1.20.8-1.0-0.10.1-0.30.1-0.11.2-0.91.21.1
Condit. Reinf. active responses0.20.30.70.60.8-0.80.7-0.7-0.5-0.7-0.60.70.50.90.8-0.80.10.3-0.60.7-0.2-0.40.40.2-0.30.30.00.0-0.1-0.2
Condit. Reinf. inactive responses0.20.31.00.30.1-0.10.3-0.3-0.5-0.8-0.10.80.71.00.5-0.5-0.4-0.3-0.20.40.5-0.50.50.5-0.50.5-0.50.6-0.7-0.6
Incentive salience index mean0.10.20.50.20.6-0.60.4-0.4-0.1-0.0-0.50.0-0.10.20.5-0.50.60.7-0.70.3-0.60.1-0.1-0.30.2-0.20.4-0.50.30.2
Condit. Reinf. lever presses0.10.10.70.10.2-0.20.2-0.2-0.9-0.3-0.20.30.20.30.6-0.60.40.2-0.30.3-0.0-0.20.20.1-0.20.20.10.1-0.0-0.1
Condit. Reinf. active minus inactive responses1.01.32.5-0.40.4-0.4-0.20.3-0.31.0-0.4-1.0-1.6-0.4-1.11.11.51.4-1.3-1.1-1.41.4-1.4-1.41.4-1.41.5-1.51.51.4
Condit. Reinf. active-inactive response ratio0.50.61.1-0.40.1-0.1-0.30.4-0.20.7-0.1-0.7-1.0-0.2-1.01.00.80.7-0.8-0.7-0.90.9-0.9-1.01.0-1.00.8-0.90.80.8
Condit. Reinf. active responses0.50.71.80.61.2-1.20.8-0.7-0.3-0.0-1.1-0.0-0.70.2-0.00.01.31.3-1.2-0.0-0.90.5-0.5-0.50.4-0.41.2-0.91.21.1
Condit. Reinf. inactive responses0.60.72.11.21.5-1.51.3-1.2-0.6-0.8-1.30.80.20.80.9-0.90.90.9-0.90.7-0.3-0.30.30.2-0.30.40.8-0.30.70.7
Condit. Reinf. lever presses1.01.34.11.52.0-2.01.8-1.7-0.4-1.0-2.01.00.21.21.1-1.11.31.3-1.51.0-0.6-0.30.30.1-0.30.41.0-0.60.80.8
Condit. Reinf. lever reinforcers received0.40.62.00.91.4-1.41.1-1.10.1-0.3-1.30.3-0.20.30.4-0.41.11.2-1.10.4-0.60.1-0.1-0.20.00.00.9-0.60.80.8
Conditioned reinforcement - actives0.60.61.50.90.5-0.51.0-1.00.1-1.0-0.61.00.70.90.3-0.3-0.2-0.30.21.20.9-1.21.21.0-1.00.9-0.00.70.00.1
Conditioned reinforcement - inactives0.20.20.8-0.3-0.90.9-0.50.50.70.40.5-0.4-0.2-0.3-0.50.50.2-0.20.4-0.20.30.3-0.2-0.20.3-0.30.10.00.10.4
Conditioned locomotion0.80.92.61.20.8-0.81.4-1.40.6-1.2-1.01.20.81.00.3-0.3-0.1-0.2-0.01.61.0-1.41.41.1-1.11.1-0.20.7-0.2-0.1
Patch foraging indifference point 0 sec0.81.43.61.61.4-1.41.6-1.6-1.0-1.4-1.41.41.00.81.9-1.90.20.4-0.41.40.4-1.21.20.9-1.11.10.40.50.40.4
Patch foraging indifference point AUC0.91.03.31.31.3-1.31.4-1.4-1.5-1.1-1.51.00.31.80.5-0.50.90.9-1.40.8-0.7-0.40.40.1-0.20.20.9-0.30.80.7
Delay disc. indifference point, 0s delay1.21.32.6-1.1-1.11.1-1.51.50.71.41.0-1.5-1.1-0.8-1.51.50.30.30.0-1.6-0.71.5-1.5-1.41.5-1.50.0-1.0-0.2-0.1
Delay disc. indifference point, 16s delay0.30.30.90.60.9-0.90.8-0.80.6-0.4-0.90.4-0.10.50.6-0.60.60.7-0.70.5-0.4-0.20.2-0.0-0.10.10.5-0.30.40.4
Delay disc. indifference point, 2s delay0.70.82.0-0.30.0-0.0-0.40.4-0.71.0-0.1-1.0-1.4-0.6-1.21.20.90.9-0.7-0.8-1.11.0-1.0-1.21.2-1.30.8-1.10.71.0
Delay disc. indifference point, 24s delay0.10.10.3-0.00.3-0.30.2-0.20.3-0.0-0.30.0-0.20.3-0.20.20.30.3-0.4-0.0-0.50.1-0.1-0.20.2-0.20.4-0.30.50.3
Delay disc. indifference point, 4s delay1.71.73.5-1.0-0.40.4-1.01.1-0.01.60.3-1.6-1.9-0.8-1.51.51.21.1-0.8-1.6-1.61.8-1.8-1.81.9-1.90.8-1.60.70.6
Delay disc. indifference point, 8s delay4.34.48.5-1.9-0.70.7-1.71.80.32.60.7-2.6-2.9-1.8-2.42.41.71.7-1.1-2.6-2.52.8-2.8-2.72.8-2.81.6-2.31.71.4
Indifference point function ln k2.02.87.2-0.6-1.51.5-0.90.80.5-0.51.70.61.8-0.81.0-1.0-2.5-2.72.60.72.5-1.51.51.9-1.71.7-2.32.2-2.1-2.0
Indifference point function log k2.02.87.2-0.6-1.51.5-0.90.80.5-0.51.70.61.8-0.81.0-1.0-2.5-2.72.60.72.5-1.51.51.9-1.71.7-2.32.2-2.1-2.0
Patch foraging total patch changes 0 sec1.21.95.01.81.5-1.51.8-1.8-1.2-1.7-1.51.71.41.02.2-2.20.00.2-0.31.70.5-1.41.41.2-1.41.40.20.70.20.2
Patch foraging total patch changes 12 sec1.82.45.02.11.7-1.72.1-2.2-0.9-2.2-1.82.21.62.21.9-1.90.40.4-0.92.00.4-1.61.61.2-1.41.40.00.7-0.1-0.3
Patch foraging total patch changes 18 sec2.83.68.72.62.8-2.82.8-2.7-1.9-1.4-3.01.40.31.61.9-1.92.12.2-2.41.5-1.4-0.60.6-0.0-0.40.42.0-0.82.11.8
Patch foraging total patch changes 24 sec1.01.33.70.41.1-1.10.6-0.50.10.4-1.1-0.5-1.0-0.20.1-0.11.91.9-1.6-0.4-1.90.9-0.9-1.21.0-1.01.7-1.41.71.4
Patch foraging total patch changes 6 sec1.11.63.41.81.2-1.21.6-1.7-0.9-1.7-1.31.71.41.71.8-1.8-0.10.2-0.21.70.4-1.41.41.1-1.31.3-0.10.7-0.1-0.1
Patch foraging time to switch 0 sec0.30.41.5-0.6-0.50.5-0.60.61.20.80.3-0.8-0.7-0.5-0.80.80.50.4-0.2-0.7-0.40.8-0.8-0.70.7-0.70.2-0.60.20.1
Patch foraging water rate 0 sec0.30.51.61.01.3-1.31.0-1.0-1.0-0.9-1.00.90.40.70.7-0.70.10.3-0.60.7-0.3-0.50.50.4-0.50.50.40.10.40.5
Patch foraging water rate 12 sec2.13.25.90.4-0.90.9-0.1-0.11.4-1.31.01.32.3-0.31.8-1.8-2.0-2.42.31.52.3-2.12.12.2-2.12.1-2.32.4-2.2-2.2
Patch foraging water rate 18 sec0.40.51.30.90.8-0.80.8-0.80.1-0.8-0.50.80.90.31.2-1.2-0.3-0.30.11.10.5-1.01.00.8-0.90.9-0.30.5-0.3-0.2
Patch foraging water rate 24 sec1.41.94.12.01.9-1.91.9-1.90.2-1.6-1.61.61.41.12.0-2.00.40.1-0.91.80.2-1.41.41.1-1.31.40.20.60.20.1
Patch foraging water rate 6 sec1.21.84.6-0.5-1.01.0-0.60.50.5-0.71.30.71.5-0.10.5-0.5-2.0-2.21.90.61.8-1.31.31.4-1.31.2-2.11.7-2.0-2.1
Seeking ratio, delayed vs. immediate footshock0.30.36.90.20.1-0.1-0.10.0-2.6-0.10.00.1-0.20.9-0.50.5-0.3-0.0-0.1-0.0-0.1-0.00.0-0.10.2-0.30.3-0.10.60.6
Distance traveled before self-admin1.21.32.8-0.9-0.70.7-1.01.10.31.40.5-1.4-1.4-0.9-1.31.30.70.9-0.5-1.6-1.01.7-1.7-1.51.5-1.50.8-1.20.80.8
Distance traveled after self-admin1.21.33.91.62.0-2.01.7-1.7-0.0-1.2-1.71.20.51.01.5-1.50.90.9-1.21.0-0.4-0.60.60.6-0.80.80.8-0.10.80.8
Extensor digitorum longus weight1.24.78.52.00.6-0.61.6-1.7-2.1-2.7-0.62.72.92.32.4-2.4-1.8-2.01.12.62.6-2.92.92.7-2.82.7-1.52.5-1.3-1.2
Bone: elastic displacement2.42.75.90.3-0.90.9-0.1-0.0-0.5-1.51.01.52.21.11.1-1.1-2.4-2.31.71.32.4-1.91.92.1-1.91.9-2.22.2-2.0-2.0
Bone: elastic work1.82.37.1-1.1-2.02.0-1.41.30.5-0.02.10.01.1-0.6-0.10.1-2.7-2.42.50.02.0-0.80.81.2-1.00.9-2.21.7-2.0-2.0
Bone: endosteal estimation2.45.313.70.82.8-2.81.8-1.72.41.4-2.8-1.4-2.5-1.7-0.30.33.63.7-2.9-0.3-3.11.5-1.5-2.31.8-1.73.0-3.22.62.5
Bone: endosteal perimeter4.59.318.2-0.71.6-1.60.2-0.12.23.2-1.7-3.2-4.2-3.0-2.02.04.24.2-2.9-2.1-4.23.3-3.3-3.93.5-3.33.8-4.33.53.5
Epididymis fat weight0.71.77.3-0.6-1.01.0-0.50.42.7-0.21.00.20.9-0.90.0-0.0-1.8-1.71.90.21.5-0.90.81.0-0.90.9-2.11.3-2.3-2.2
Delta time in closed arm before/after self-admin1.11.02.9-0.20.8-0.8-0.10.20.20.9-0.4-0.9-1.3-0.7-0.90.91.21.2-1.2-0.8-1.71.1-1.1-1.31.2-1.21.2-1.31.21.3
Delta time in open arm before/after self-admin0.60.62.21.10.5-0.50.9-0.9-1.0-1.1-0.61.10.91.51.0-1.00.10.0-0.41.00.4-0.80.80.7-0.70.70.00.50.10.0
Diff in mean of infusions in LGA sessions0.40.51.50.70.8-0.80.7-0.7-0.10.6-0.9-0.5-0.6-1.2-0.00.01.11.0-0.50.3-0.90.1-0.1-0.60.4-0.30.9-0.90.70.8
Delay discount exponential model param1.92.04.21.20.2-0.20.9-1.0-0.7-1.7-0.21.72.11.11.5-1.5-1.4-1.31.01.61.9-1.81.81.9-1.91.9-1.11.7-1.0-0.8
Extinction: sum of active levers before priming0.40.41.0-0.3-0.40.4-0.30.20.2-0.30.70.30.8-0.20.6-0.6-0.9-0.91.00.30.7-0.60.60.7-0.70.7-1.00.9-0.9-0.9
Active lever presses in extinction session 60.30.31.11.00.4-0.41.0-1.00.9-0.4-0.90.40.2-0.20.3-0.3-0.00.40.00.90.4-0.60.60.3-0.40.40.1-0.0-0.1-0.0
Bone: final force1.11.84.0-2.0-2.02.0-1.91.91.51.22.0-1.1-0.4-1.3-1.41.4-1.3-1.21.8-1.20.60.6-0.7-0.10.4-0.5-1.30.3-1.3-1.4
Bone: final moment1.11.73.9-1.9-2.02.0-1.91.91.41.22.0-1.2-0.4-1.4-1.41.4-1.3-1.21.8-1.20.60.6-0.6-0.20.4-0.4-1.20.3-1.2-1.2
Food consumed during 24 hour testing period1.41.74.80.51.1-1.10.5-0.4-0.60.5-1.1-0.5-1.30.3-0.30.31.81.8-2.0-0.7-1.91.2-1.2-1.31.2-1.22.1-1.62.22.2
Glucose0.50.72.5-0.1-0.80.8-0.40.4-0.2-0.30.80.30.90.00.3-0.3-1.6-1.41.40.31.2-0.80.81.0-0.90.9-1.01.1-0.7-0.7
Heart weight1.82.67.4-0.9-2.02.0-1.21.10.5-0.21.90.31.4-0.80.3-0.3-2.5-2.52.70.32.3-1.11.11.5-1.31.3-2.32.1-2.2-2.1
Delay discount hyperbolic model param1.71.84.11.10.2-0.20.8-0.9-0.4-1.6-0.11.62.01.01.5-1.5-1.3-1.30.91.51.8-1.81.81.8-1.81.8-1.11.6-1.0-0.9
Intermittent access intake day 1-15 change0.60.61.1-0.4-0.40.4-0.50.5-0.30.70.3-0.7-0.80.2-1.01.00.70.7-0.6-0.8-0.80.9-0.9-0.91.0-1.00.9-0.71.11.0
Intermittent access intake escalation0.90.92.50.00.2-0.2-0.00.1-0.80.5-0.3-0.6-1.00.4-0.70.71.21.2-1.2-0.7-1.21.0-1.0-1.01.0-1.01.4-1.01.61.5
Intermittent access intake escalation 20.60.62.20.20.3-0.30.2-0.2-0.80.2-0.4-0.2-0.80.8-1.51.50.80.8-1.0-0.2-0.70.5-0.5-0.70.7-0.81.2-0.71.51.2
Intermitt. access day 1 inactive lever presses1.31.42.5-1.0-0.90.9-1.01.00.21.60.5-1.6-1.5-1.4-0.90.91.01.1-0.4-1.3-1.01.5-1.5-1.41.4-1.41.3-1.21.31.3
Intermitt. access day 15 inactive lever presses0.20.20.70.70.5-0.50.6-0.60.1-0.4-0.60.40.20.80.3-0.30.30.4-0.60.5-0.1-0.30.30.0-0.10.10.2-0.1-0.10.2
Intermitt. access escalation Index0.90.82.8-0.30.4-0.4-0.20.2-0.60.9-0.2-0.9-1.1-0.70.1-0.10.91.2-0.8-0.5-1.70.9-0.9-1.21.1-1.11.2-1.31.31.1
Intermittent access day 1 total infusions0.40.51.20.0-0.40.40.0-0.01.1-0.20.30.20.7-0.70.7-0.7-0.6-0.81.10.41.0-0.60.60.7-0.80.8-0.90.8-1.1-0.8
Intermittent access day 15 total infusions0.20.20.90.30.3-0.30.2-0.20.30.2-0.4-0.2-0.4-0.0-0.10.10.70.7-0.4-0.1-0.50.3-0.3-0.40.3-0.30.8-0.40.60.9
Intermittent access terminal intake (last 3 days)0.20.20.90.10.0-0.00.1-0.10.90.5-0.2-0.4-0.5-0.4-0.40.40.80.6-0.2-0.1-0.50.3-0.2-0.50.4-0.40.6-0.50.40.7
Intermittent access total infusions0.10.11.50.2-0.00.00.2-0.21.20.1-0.2-0.1-0.0-0.60.3-0.30.40.20.20.10.1-0.10.10.0-0.10.10.1-0.1-0.20.2
Intermittent access day 1 locomotion0.50.51.00.80.6-0.60.9-0.90.0-0.9-0.70.90.80.50.9-0.9-0.0-0.20.20.90.8-0.80.80.9-1.01.0-0.30.6-0.3-0.4
Intermittent access day 15 total locomotion0.10.10.4-0.1-0.50.5-0.20.2-0.10.10.2-0.1-0.1-0.3-0.50.5-0.1-0.40.6-0.10.6-0.10.10.2-0.20.20.10.30.30.3
Intermittent access total locomotion0.20.30.60.50.2-0.20.6-0.60.4-0.7-0.40.70.50.30.3-0.3-0.1-0.40.30.60.8-0.70.70.7-0.80.8-0.20.6-0.1-0.0
Intermittent access standard deviation2.62.86.4-2.4-1.91.9-2.22.22.52.11.9-2.1-1.3-2.1-2.22.2-0.4-0.51.3-1.9-0.31.4-1.4-1.21.4-1.4-0.7-0.5-0.9-0.8
Left kidney weight1.85.210.7-3.3-2.92.9-3.23.22.12.92.8-2.9-2.0-3.2-3.03.0-0.7-0.81.7-2.8-0.32.0-2.0-1.61.8-1.9-0.7-0.6-0.6-0.7
Right kidney weight0.92.45.8-2.3-2.42.4-2.32.30.51.62.2-1.6-1.0-1.8-2.12.1-1.1-1.21.8-1.80.71.0-1.0-0.60.9-0.9-1.00.2-0.8-0.8
Cocaine induced anxiety1.31.57.2-1.4-0.10.1-0.80.82.71.10.2-1.2-1.5-0.2-1.41.41.40.8-1.0-1.5-1.31.6-1.6-1.41.4-1.50.5-1.30.40.2
Post-drug Anxiety0.91.08.0-0.30.7-0.70.2-0.22.80.4-0.7-0.4-0.90.2-0.40.41.61.2-1.6-0.5-1.30.9-0.9-1.00.9-0.90.6-1.10.30.1
Baseline Anxiety0.30.30.80.5-0.30.30.3-0.3-0.5-0.4-0.00.40.7-0.10.8-0.8-0.9-0.40.70.90.7-0.80.80.6-0.60.6-0.50.6-0.6-0.4
Tail length1.13.410.31.11.7-1.71.0-0.9-1.90.2-1.9-0.3-1.70.9-1.21.22.82.5-2.7-0.8-2.01.5-1.5-1.41.3-1.33.0-1.93.23.1
Length with tail1.24.210.5-2.1-1.41.4-2.02.10.52.51.1-2.5-2.8-2.0-3.23.21.10.9-0.3-2.8-1.52.6-2.6-2.22.4-2.41.3-1.71.41.4
Length without tail2.76.013.5-3.7-3.53.5-3.53.52.42.73.5-2.7-1.5-3.2-2.82.8-1.9-1.72.7-2.50.51.5-1.5-1.01.4-1.5-1.70.1-1.7-1.6
Times rat made contact with spout0.40.41.20.80.9-0.90.7-0.7-0.8-0.4-0.80.4-0.00.60.4-0.41.00.6-1.10.4-0.6-0.10.1-0.1-0.00.00.9-0.31.11.1
Lifetime Intake0.20.35.2-0.1-0.30.3-0.00.02.30.20.0-0.20.1-0.80.1-0.10.1-0.00.5-0.10.3-0.00.00.1-0.10.1-0.30.1-0.6-0.3
Liver weight, left1.52.47.5-2.1-1.51.5-1.81.82.72.11.4-2.1-1.5-2.2-1.71.70.10.10.7-1.9-0.71.6-1.6-1.41.5-1.5-0.3-0.9-0.5-0.5
Liver weight, right0.91.43.3-1.8-1.81.8-1.71.70.91.21.6-1.2-0.7-1.2-1.51.5-0.9-0.81.2-1.20.50.7-0.8-0.50.7-0.7-1.00.1-1.1-1.1
Locomotor activity0.10.12.00.10.1-0.10.2-0.2-1.4-0.2-0.20.2-0.10.1-0.10.1-0.2-0.10.20.20.3-0.30.30.1-0.10.10.00.1-0.00.2
Locomotor testing distance0.30.51.40.61.0-1.00.8-0.8-1.20.0-1.0-0.1-0.6-0.0-0.20.20.90.8-0.60.1-0.50.1-0.1-0.30.2-0.20.9-0.70.81.0
Locomotor testing rearing0.81.35.01.51.6-1.61.6-1.6-2.2-1.0-1.71.00.11.60.8-0.81.01.1-1.31.0-0.4-0.40.50.2-0.30.31.1-0.31.01.1
Locomotion in novel chamber1.92.46.41.62.1-2.11.8-1.8-1.1-0.3-2.30.2-0.81.00.6-0.62.12.5-2.40.4-1.80.5-0.5-0.90.7-0.62.2-1.61.82.1
Locomotion in novel chamber post-restriction0.91.12.90.51.3-1.30.6-0.60.60.5-1.1-0.5-0.9-0.30.0-0.01.61.7-1.3-0.5-1.51.0-1.0-1.00.8-0.71.7-1.31.61.7
Fecal boli incidents, locomotor time 10.80.91.60.80.8-0.81.2-1.21.2-0.9-0.91.00.90.41.0-1.0-0.4-0.20.31.20.7-1.11.11.0-1.11.1-0.70.6-1.1-0.9
Change in fecal boli incidents, locomotor task0.30.30.7-0.2-0.40.4-0.10.1-0.1-0.40.40.50.70.10.5-0.5-0.6-0.70.50.30.7-0.50.50.7-0.70.7-0.80.8-0.8-0.9
Time >=10cm from walls, locomotor time 11.21.23.90.40.9-0.90.4-0.3-0.90.5-0.9-0.5-0.90.1-0.60.61.41.5-1.5-0.5-1.51.0-1.0-1.00.9-0.91.8-1.32.01.9
Bouts of movement, locomotor time 10.91.02.1-0.4-1.01.0-0.30.20.2-0.50.60.51.1-0.00.8-0.8-1.4-1.41.20.71.4-1.11.11.0-1.01.0-1.41.3-1.5-1.4
Total resting periods, locomotor time 10.90.91.8-0.2-0.90.9-0.10.1-0.1-0.60.50.61.10.21.2-1.2-1.3-1.31.10.81.3-1.11.11.0-1.01.0-1.31.3-1.3-1.2
Rest time, locomotor task time 11.01.13.3-0.9-1.21.2-0.70.71.30.01.20.00.6-0.60.5-0.5-1.5-1.51.70.11.2-0.60.60.8-0.70.7-1.61.1-1.8-1.5
Distance moved, locomotor task time 10.91.04.00.91.0-1.00.6-0.5-1.7-0.0-0.9-0.0-0.60.6-0.30.31.31.2-1.3-0.2-1.00.6-0.6-0.70.6-0.61.7-0.92.01.9
Vertical activity count, locomotor time 10.70.81.91.21.3-1.31.1-1.1-0.7-0.8-1.30.7-0.11.2-0.10.11.10.9-1.40.7-0.4-0.20.2-0.0-0.10.01.1-0.41.21.3
Time >=10cm from walls, locomotor time 20.30.33.20.5-0.30.3-0.0-0.0-1.8-0.50.20.50.50.8-0.30.3-0.4-0.50.20.30.7-0.50.50.5-0.40.40.30.50.80.6
Bouts of movement, locomotor time 20.10.10.3-0.20.1-0.1-0.10.10.50.3-0.1-0.3-0.3-0.60.1-0.10.20.2-0.1-0.2-0.40.2-0.2-0.20.2-0.10.3-0.20.30.5
Total resting periods, locomotor time 20.10.10.6-0.10.3-0.30.1-0.00.80.3-0.2-0.3-0.4-0.60.1-0.10.40.4-0.2-0.2-0.50.3-0.3-0.30.2-0.20.4-0.40.30.6
Rest time, locomotor task time 20.40.45.4-0.70.3-0.30.0-0.02.30.6-0.1-0.6-0.7-1.1-0.20.20.50.5-0.1-0.3-0.60.4-0.4-0.40.3-0.3-0.2-0.5-0.8-0.4
Distance moved, locomotor task time 20.50.64.40.0-1.01.0-0.60.6-2.1-0.40.90.30.60.6-0.50.5-1.1-1.21.00.11.1-0.50.50.6-0.30.3-0.50.80.1-0.2
Vertical activity count, locomotor time 20.30.41.30.0-0.70.7-0.20.2-0.3-0.50.60.50.60.2-0.50.5-0.9-1.00.80.41.1-0.70.70.7-0.60.6-0.60.9-0.2-0.4
Light reinforcement 11.01.73.61.70.8-0.81.5-1.5-1.8-1.9-1.11.91.51.81.7-1.7-0.2-0.3-0.21.61.0-1.51.51.4-1.41.4-0.21.1-0.1-0.1
Light reinforcement 20.00.00.2-0.1-0.40.4-0.30.30.1-0.20.30.10.10.2-0.20.2-0.0-0.20.1-0.30.20.1-0.1-0.00.1-0.1-0.20.2-0.2-0.1
Bone: marrow area2.55.313.80.82.8-2.81.8-1.72.41.4-2.8-1.4-2.6-1.7-0.30.33.63.7-2.9-0.3-3.11.6-1.6-2.41.9-1.83.0-3.22.62.5
Bone: maximum diameter3.05.613.9-2.6-1.01.0-1.81.93.03.51.0-3.4-3.3-3.7-2.62.61.41.5-0.1-2.6-2.12.7-2.7-2.82.8-2.71.2-2.50.91.0
Bone: maximum force0.91.55.2-1.6-1.61.6-1.51.52.31.01.6-1.0-0.2-1.6-1.11.1-1.3-1.11.8-0.90.70.4-0.40.00.2-0.2-1.30.4-1.4-1.4
Bone: maximum moment0.81.45.0-1.5-1.61.6-1.41.42.21.01.6-1.0-0.2-1.7-0.90.9-1.3-1.11.8-0.80.60.3-0.30.00.2-0.2-1.20.3-1.2-1.2
Mean time between licks in bursts0.10.10.7-0.3-0.40.4-0.30.30.4-0.00.40.00.30.20.0-0.0-0.5-0.60.30.10.4-0.20.20.3-0.20.2-0.70.3-0.8-0.8
Mean num. licks in bursts0.40.51.11.00.8-0.80.9-0.90.2-0.9-0.70.90.80.81.0-1.00.60.0-0.71.00.2-0.80.80.6-0.70.70.10.30.10.0
Cd content in liver2.32.66.30.5-0.70.70.1-0.2-1.1-1.40.81.42.11.01.4-1.4-2.5-2.12.11.42.2-1.91.92.0-1.91.9-1.82.1-1.6-1.5
Co content in liver0.91.12.31.20.5-0.51.0-1.00.9-1.1-0.51.11.40.51.5-1.5-0.6-0.50.41.51.0-1.41.41.1-1.21.2-0.70.9-0.7-0.8
Cu content in liver0.10.20.5-0.2-0.60.6-0.40.3-0.7-0.00.70.00.2-0.30.0-0.0-0.5-0.60.60.20.6-0.40.40.3-0.20.2-0.30.50.0-0.3
Fe content in liver1.01.23.90.51.2-1.20.8-0.80.00.5-1.2-0.5-1.1-0.30.2-0.21.62.0-1.6-0.1-1.60.8-0.8-1.20.9-0.91.7-1.51.61.4
K content in liver0.40.42.00.30.4-0.40.1-0.1-1.40.1-0.4-0.1-0.50.3-0.00.00.60.8-0.7-0.3-0.90.5-0.5-0.60.5-0.51.1-0.71.21.2
Mg content in liver1.21.23.01.71.3-1.31.4-1.4-1.6-1.4-1.31.31.01.51.4-1.40.20.2-0.61.20.2-0.90.90.8-0.90.90.70.20.80.9
Mn content in liver1.01.12.5-1.0-0.60.6-1.11.10.21.30.6-1.3-1.4-1.0-1.61.60.40.7-0.3-1.4-0.91.4-1.4-1.21.3-1.30.7-1.00.60.7
Na content in liver0.91.02.1-0.30.1-0.1-0.30.4-0.40.9-0.1-0.9-1.3-0.3-0.90.91.21.2-1.0-1.0-1.41.3-1.3-1.21.2-1.21.3-1.31.41.4
Rb content in liver1.11.44.81.41.1-1.11.3-1.3-1.4-1.8-1.01.71.52.21.1-1.1-0.5-0.3-0.21.30.7-1.21.21.3-1.31.3-0.40.9-0.3-0.5
Se content in liver1.31.65.71.01.4-1.41.0-0.9-2.4-0.1-1.40.1-0.90.9-0.20.21.51.8-1.90.0-1.50.6-0.6-0.90.8-0.82.0-1.32.22.0
Sr content in liver0.60.61.8-0.4-1.11.1-0.70.70.5-0.01.00.00.6-0.4-0.00.0-1.3-1.21.3-0.01.0-0.40.40.6-0.40.4-1.00.9-0.9-0.8
Zn content in liver0.60.71.7-1.3-1.31.3-1.21.20.31.01.3-1.0-0.4-1.3-0.60.6-0.4-0.51.0-0.80.10.5-0.5-0.40.5-0.4-0.5-0.0-0.5-0.5
Bone: minimum diameter1.12.14.7-1.20.0-0.0-0.50.61.32.0-0.1-2.0-2.2-2.1-1.31.31.51.6-0.6-1.3-1.71.7-1.6-1.91.8-1.71.3-1.91.11.1
Time in familiar zone, hab. session 10.20.20.70.1-0.20.20.1-0.2-0.2-0.4-0.00.40.60.30.9-0.9-0.5-0.40.20.50.5-0.50.50.4-0.50.5-0.50.5-0.5-0.6
Time in novel zone, hab. session 10.70.61.5-0.5-0.20.2-0.50.50.80.90.2-0.9-1.0-0.3-1.21.20.90.7-0.5-1.0-0.81.0-1.0-0.91.0-1.00.6-0.90.60.6
Total zone transitions, hab. session 11.01.43.91.41.1-1.11.3-1.3-1.8-1.8-1.01.71.42.01.3-1.3-0.2-0.3-0.21.20.8-1.21.21.3-1.31.3-0.20.8-0.2-0.2
Total locomotion distance, hab. session 10.91.33.71.30.7-0.71.1-1.2-1.9-1.7-0.71.61.41.51.3-1.3-0.4-0.50.11.31.0-1.31.31.4-1.41.3-0.31.1-0.1-0.2
Locomotion velocity, hab. session 11.42.06.91.40.7-0.71.2-1.2-2.6-2.0-0.72.01.71.71.5-1.5-0.8-0.80.31.61.4-1.61.61.7-1.71.7-0.51.4-0.2-0.3
Time in familiar zone, hab. session 20.20.21.30.40.0-0.00.2-0.31.1-0.4-0.10.40.5-0.00.5-0.5-0.4-0.40.30.40.4-0.40.40.4-0.50.5-0.40.4-0.4-0.3
Time in novel zone, hab. session 20.20.20.4-0.5-0.10.1-0.40.4-0.00.60.1-0.6-0.6-0.3-0.40.40.50.5-0.1-0.4-0.60.5-0.5-0.60.6-0.60.4-0.60.40.3
Total zone transitions, hab. session 23.54.69.22.72.0-2.02.5-2.5-2.0-3.0-1.93.02.62.82.6-2.6-0.7-0.5-0.22.61.4-2.42.42.4-2.52.5-0.61.6-0.6-0.5
Total locomotion distance, hab. session 23.74.99.52.61.3-1.32.1-2.2-2.2-3.1-1.33.12.82.52.7-2.7-1.3-1.20.42.72.1-2.72.72.7-2.82.7-0.92.2-0.6-0.6
Locomotion velocity, hab. session 23.54.79.42.51.2-1.22.1-2.1-2.5-3.1-1.33.02.72.52.6-2.6-1.3-1.20.42.62.1-2.62.62.7-2.72.7-0.82.1-0.5-0.5
Novel to familiar place preference ratio1.81.83.82.01.5-1.51.8-1.8-0.7-1.7-1.41.71.51.41.8-1.8-0.20.0-0.41.70.7-1.51.51.3-1.51.50.10.80.10.1
Novelty place preference1.41.43.01.71.4-1.41.7-1.7-0.5-1.5-1.31.51.21.21.6-1.6-0.00.2-0.51.50.5-1.31.31.1-1.21.30.20.50.20.1
Time in novel zone, NPP test1.61.73.51.91.5-1.51.7-1.8-0.6-1.7-1.41.71.41.41.8-1.8-0.20.1-0.41.60.6-1.41.41.3-1.41.40.10.70.10.0
Total zone transitions, NPP test2.13.06.72.11.4-1.41.9-1.9-1.8-2.6-1.42.62.12.32.0-2.0-0.6-0.6-0.12.11.3-1.91.92.0-2.02.0-0.51.4-0.5-0.5
Total locomotion distance, NPP test5.06.812.92.71.1-1.12.1-2.2-3.3-3.6-1.13.63.42.83.1-3.1-1.8-1.80.83.12.7-3.23.23.3-3.33.3-1.22.8-0.9-0.9
Locomotion velocity, NPP test4.15.811.22.51.1-1.12.0-2.1-2.9-3.3-1.13.33.12.62.9-2.9-1.6-1.60.72.92.5-2.92.93.0-3.13.0-1.22.6-0.9-0.9
Intraocular pressure1.21.64.82.01.9-1.92.2-2.2-0.1-0.9-2.21.00.40.31.5-1.50.81.3-0.91.5-0.2-1.01.00.3-0.70.71.0-0.31.00.8
Delta distance traveled before/after self-admin2.22.44.31.71.8-1.82.0-2.0-0.6-2.1-1.52.11.61.72.0-2.0-0.1-0.3-0.32.00.7-1.81.81.7-1.91.9-0.21.1-0.2-0.2
Delta ambulatory time before/after self-admin2.52.85.52.12.2-2.22.3-2.4-0.6-2.1-1.92.11.51.92.2-2.20.20.1-0.72.20.4-1.81.81.6-1.81.80.20.80.20.1
Parametrial fat weight0.10.20.8-0.2-0.60.6-0.10.10.90.00.20.00.1-0.5-0.30.3-0.7-0.20.80.20.7-0.20.20.2-0.20.2-0.60.4-0.8-0.8
Pavlov. Cond. lever latency0.91.23.71.81.7-1.71.7-1.70.7-0.6-1.90.60.10.70.9-0.90.91.2-1.20.9-0.6-0.30.3-0.1-0.20.21.2-0.61.21.2
Pavlov. Cond. magazine entry latency1.72.24.4-1.7-0.80.8-1.41.4-0.11.90.7-1.9-2.1-1.6-1.81.81.41.0-0.6-1.8-1.41.9-1.9-1.81.9-1.91.1-1.51.11.0
Pavlov. Cond. change in total contacts1.01.02.0-0.1-0.50.5-0.10.1-0.8-0.80.70.81.20.30.9-0.9-1.3-1.31.20.71.4-1.11.11.3-1.21.2-1.41.3-1.4-1.4
Pavlov. Cond. index score0.91.23.1-1.8-1.21.2-1.51.60.01.41.3-1.4-1.2-1.4-1.31.30.3-0.00.3-1.4-0.41.2-1.2-0.91.1-1.1-0.1-0.5-0.1-0.1
Pavlov. Cond. latency score1.31.74.6-2.1-1.61.6-1.92.00.11.61.7-1.6-1.3-1.6-1.61.60.1-0.20.5-1.7-0.41.3-1.3-1.01.2-1.2-0.3-0.4-0.3-0.4
Pavlov. Cond. lever contacts0.70.82.3-1.1-1.31.3-1.11.1-0.90.01.5-0.00.5-0.40.0-0.0-1.1-1.31.2-0.10.9-0.30.30.6-0.40.4-1.21.0-1.2-1.2
Pavlov. Cond. magazine entry number1.82.24.22.01.2-1.21.7-1.7-0.8-2.1-1.22.01.92.01.8-1.8-0.9-0.5-0.01.91.0-1.71.71.6-1.71.7-0.41.2-0.3-0.3
Pavlov. Cond. intertrial magazine entries1.31.53.51.71.4-1.41.7-1.8-0.6-1.6-1.51.61.31.91.6-1.6-0.20.1-0.71.60.3-1.21.21.0-1.11.2-0.00.5-0.1-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.82.2-1.5-1.11.1-1.31.3-0.41.11.1-1.1-1.0-1.1-1.11.10.3-0.00.3-1.1-0.30.9-0.9-0.70.9-0.9-0.0-0.4-0.1-0.1
Pavlov. Cond. response bias0.70.92.6-1.6-1.21.2-1.41.40.21.21.2-1.2-1.0-1.3-1.11.10.2-0.10.4-1.1-0.30.9-1.0-0.80.9-0.9-0.2-0.4-0.2-0.2
Pavlov. Cond. lever latency1.52.05.9-1.9-2.42.4-2.32.20.41.12.4-1.1-0.2-1.1-1.41.4-1.6-1.51.7-1.20.60.5-0.5-0.20.5-0.5-1.20.6-1.1-1.1
Pavlov. Cond. magazine entry latency0.81.02.91.00.6-0.61.1-1.20.7-0.9-0.71.01.20.21.7-1.7-0.3-0.20.41.30.8-1.21.21.0-1.21.2-0.50.8-0.6-0.6
Pavlov. Cond. change in total contacts1.11.53.61.71.6-1.61.9-1.9-0.3-1.2-1.71.20.91.01.9-1.90.80.6-0.91.40.2-1.11.10.8-1.01.10.40.20.30.3
Pavlov. Cond. index score1.01.33.31.51.7-1.71.8-1.8-0.2-1.0-1.81.00.60.81.7-1.70.90.9-0.91.2-0.0-0.80.80.5-0.80.80.6-0.10.40.4
Pavlov. Cond. latency score0.81.02.81.41.6-1.61.7-1.70.0-0.8-1.70.80.40.51.5-1.51.01.0-0.91.1-0.2-0.60.60.3-0.60.60.6-0.20.40.5
Pavlov. Cond. lever contacts1.62.26.21.82.5-2.52.2-2.1-1.0-1.0-2.41.0-0.01.41.2-1.21.81.8-2.01.0-1.0-0.30.3-0.0-0.20.31.5-0.81.31.3
Pavlov. Cond. magazine entry number1.11.44.3-1.5-1.01.0-1.51.60.21.31.1-1.3-1.3-0.6-2.12.10.0-0.0-0.0-1.5-0.81.4-1.4-1.11.3-1.40.1-0.70.20.1
Pavlov. Cond. intertrial magazine entries2.53.37.80.82.1-2.11.0-0.9-1.50.4-1.9-0.5-1.90.4-1.01.02.62.5-2.7-0.6-2.61.4-1.4-1.71.5-1.52.7-2.22.82.8
Pavlov. Cond. lever-magazine prob. diff.1.11.43.81.71.8-1.81.9-1.9-0.2-1.1-1.91.10.60.91.8-1.80.90.9-1.01.3-0.1-0.80.90.5-0.80.90.6-0.10.50.5
Pavlov. Cond. response bias0.91.23.11.51.6-1.61.7-1.7-0.5-1.1-1.71.10.61.01.5-1.50.90.8-1.01.2-0.1-0.80.80.5-0.70.80.6-0.00.40.4
Time in closed arm before self-admin0.91.03.1-0.7-1.21.2-0.70.7-0.5-0.31.10.30.70.1-0.20.2-1.8-1.41.6-0.01.4-0.50.50.8-0.60.6-1.51.1-1.6-1.4
Time in closed arm after self-admin1.01.03.4-1.9-0.90.9-1.41.40.81.41.2-1.4-1.1-1.7-1.01.0-0.5-0.30.8-1.3-0.50.9-1.0-0.80.8-0.8-0.3-0.4-0.4-0.2
Time in open arm before self-admin0.30.30.8-0.5-0.50.5-0.40.40.50.70.1-0.7-0.8-0.7-0.90.90.20.3-0.0-0.6-0.10.6-0.6-0.60.6-0.60.3-0.50.30.2
Time in open arm after self-admin0.40.51.61.30.8-0.81.0-1.0-0.5-0.7-1.00.70.41.00.5-0.50.70.7-0.90.7-0.0-0.30.30.2-0.30.30.6-0.10.60.5
Bone: periosteal estimation0.91.87.3-1.20.0-0.0-0.50.52.71.9-0.0-1.9-1.9-2.6-1.21.21.01.2-0.1-1.1-1.31.4-1.4-1.61.4-1.40.7-1.60.40.4
Bone: periosteal perimeter2.54.110.7-2.7-1.71.7-2.22.32.33.01.7-2.9-2.5-3.3-2.52.50.40.40.8-2.4-1.12.2-2.2-2.12.1-2.10.3-1.50.20.1
Bone: post-yield work0.70.92.41.51.2-1.21.5-1.5-0.1-1.0-1.21.00.90.71.4-1.40.40.3-0.31.40.2-1.11.10.7-0.90.90.40.20.50.4
Progressive ratio test 1 active lever presses0.40.41.40.80.8-0.81.0-0.91.2-0.2-1.20.2-0.10.20.3-0.31.20.9-0.80.4-0.4-0.10.1-0.2-0.00.00.6-0.50.30.6
Progressive ratio test 1 breakpoint0.30.32.90.50.7-0.70.8-0.81.7-0.3-1.00.30.00.00.4-0.40.90.7-0.50.4-0.2-0.20.20.0-0.20.20.2-0.3-0.20.2
Progressive ratio test 1 inactive lever presses0.30.31.1-0.1-0.30.3-0.20.3-0.40.6-0.0-0.6-0.7-0.3-0.20.20.90.7-0.4-0.7-0.50.9-0.9-0.70.6-0.60.8-0.60.71.1
Progressive ratio test 2 active lever presses0.30.30.90.90.5-0.50.8-0.80.6-0.5-0.70.50.20.10.2-0.20.1-0.00.10.80.4-0.70.70.4-0.50.50.40.20.30.8
Progressive ratio test 2 breakpoint0.20.30.80.90.4-0.40.8-0.80.8-0.5-0.70.50.30.20.1-0.1-0.0-0.10.20.80.5-0.70.70.5-0.50.50.20.20.10.6
Progressive ratio test 2 inactive lever presses0.10.10.60.2-0.30.30.00.00.10.1-0.0-0.1-0.20.1-0.40.40.0-0.00.2-0.20.30.1-0.10.00.0-0.00.40.00.40.8
Incentive Sensitization - Responses0.30.31.4-0.4-1.21.2-0.50.50.60.50.6-0.5-0.2-0.9-0.50.5-0.7-0.61.10.00.8-0.10.10.00.0-0.0-0.10.3-0.00.4
Incentive Sensitization - Breakpoint0.40.41.6-0.5-1.31.3-0.70.60.50.60.7-0.6-0.4-1.0-0.60.6-0.7-0.61.1-0.10.7-0.00.0-0.10.2-0.20.00.20.10.5
Sum of active levers in priming session hrs 5-60.10.10.40.40.5-0.50.5-0.50.10.2-0.6-0.1-0.1-0.60.5-0.50.30.6-0.20.4-0.4-0.10.1-0.1-0.00.10.4-0.30.30.3
Progressive ratio0.40.51.20.40.0-0.00.7-0.7-0.7-0.4-0.40.40.6-0.50.9-0.9-0.6-0.50.91.10.8-1.11.10.7-0.80.9-0.60.6-0.5-0.6
Food seeking constrained by brief footshock0.40.51.3-1.0-1.01.0-0.80.70.70.60.9-0.6-0.1-1.2-0.30.3-0.5-0.70.9-0.30.4-0.00.0-0.00.1-0.1-0.90.3-1.0-0.9
Seeking ratio, punishment vs. effort0.50.61.2-0.8-0.30.3-0.80.81.00.80.5-0.8-0.8-0.3-0.90.90.70.5-0.7-1.1-0.81.1-1.1-0.91.0-1.00.4-0.70.40.4
Retroperitoneal fat weight0.30.95.9-0.9-0.60.6-0.60.72.41.20.3-1.2-1.0-1.6-1.01.00.20.40.2-1.1-0.21.1-1.1-0.90.8-0.8-0.0-0.6-0.4-0.2
Reaction time number correct2.23.28.32.92.5-2.52.8-2.8-0.4-2.0-2.71.91.12.22.2-2.21.31.4-1.92.1-0.2-1.31.30.7-1.01.01.1-0.10.90.9
Reaction time mean minus median0.60.83.5-1.2-1.91.9-1.31.2-0.50.81.4-0.7-0.4-0.9-0.90.9-0.7-0.71.1-0.60.70.3-0.3-0.20.3-0.4-0.50.3-0.3-0.3
Reaction time mean minus median AUC0.81.02.4-1.3-1.51.5-1.31.3-0.21.21.1-1.2-1.1-0.9-1.41.40.20.20.2-1.2-0.31.0-1.0-1.01.1-1.10.3-0.50.40.3
Reaction time num false alarms0.10.21.60.40.5-0.50.4-0.5-1.3-0.4-0.30.40.10.10.5-0.5-0.10.1-0.10.50.1-0.40.40.3-0.40.40.10.20.20.4
Reaction time num false alarms AUC0.30.41.70.80.9-0.90.8-0.8-1.3-0.6-0.70.60.20.40.6-0.60.10.2-0.30.70.0-0.50.50.4-0.50.50.30.20.30.6
Reaction time trials correct on left2.23.28.32.92.5-2.52.8-2.8-0.4-2.0-2.71.91.12.22.2-2.21.31.4-1.92.1-0.2-1.31.30.7-1.01.01.1-0.10.90.9
Reaction time trials on left2.23.28.32.92.5-2.52.8-2.8-0.4-1.9-2.71.91.02.12.1-2.11.31.4-1.92.1-0.2-1.21.20.7-1.01.01.1-0.20.91.0
Reaction time mean0.10.10.4-0.2-0.60.6-0.20.2-0.60.10.4-0.1-0.1-0.1-0.20.2-0.2-0.30.30.20.4-0.20.20.1-0.00.0-0.20.2-0.1-0.0
Reaction time mean AUC0.10.20.5-0.0-0.60.6-0.10.1-0.6-0.10.40.10.30.00.1-0.1-0.5-0.60.50.40.7-0.50.50.4-0.30.3-0.40.5-0.3-0.2
Median of all reaction times0.00.00.5-0.0-0.20.2-0.0-0.0-0.7-0.00.20.00.00.1-0.00.0-0.1-0.30.10.30.2-0.30.30.1-0.10.1-0.10.2-0.10.0
Reaction time omissions0.40.61.3-0.9-0.80.8-0.90.90.31.00.8-1.0-0.9-1.1-1.11.10.00.00.2-0.9-0.40.8-0.8-0.80.9-0.90.2-0.50.30.3
Reaction time false alarm rate0.20.21.1-0.7-0.50.5-0.70.7-1.10.40.8-0.4-0.4-0.7-0.50.5-0.5-0.50.6-0.50.10.2-0.2-0.10.1-0.1-0.20.2-0.10.1
Reaction time premature initiation rate2.53.46.71.20.7-0.71.1-1.2-0.0-2.3-0.32.32.61.71.8-1.8-1.5-1.71.02.12.0-2.42.32.4-2.32.3-2.02.0-2.1-2.2
Reaction time premature initiations3.75.39.62.82.1-2.12.6-2.7-0.2-3.1-1.83.12.92.62.8-2.8-0.6-0.8-0.23.11.6-2.92.92.6-2.72.7-1.11.7-1.3-1.3
Std. dev. reaction times0.20.31.4-0.4-1.21.2-0.50.5-0.50.10.8-0.10.1-0.2-0.20.2-0.6-0.70.70.10.8-0.30.30.2-0.10.1-0.50.5-0.4-0.3
Reaction time trials completed2.23.28.32.92.5-2.52.8-2.8-0.4-1.9-2.71.91.02.12.1-2.11.31.4-1.92.1-0.2-1.21.20.7-1.01.01.1-0.20.91.0
Reaction time trials AUC2.53.69.33.02.6-2.62.9-2.9-0.5-2.1-2.82.11.22.42.3-2.31.31.3-1.92.2-0.1-1.41.40.9-1.21.21.0-0.00.80.9
Run reversals in cocaine runway, females0.20.20.7-0.4-0.50.5-0.10.10.50.10.1-0.10.2-0.70.6-0.6-0.3-0.30.50.00.3-0.10.10.1-0.20.2-0.60.3-0.8-0.8
Run reversals in cocaine runway, males1.41.44.3-0.9-1.21.2-0.90.91.6-0.11.10.10.8-0.6-0.30.3-1.5-1.81.6-0.11.5-0.50.51.0-0.80.7-1.91.3-1.9-2.1
Latency to leave start box in cocaine runway0.50.51.10.50.1-0.10.3-0.3-0.2-0.8-0.00.81.00.30.8-0.8-0.9-0.80.70.60.8-0.80.81.0-1.01.0-0.60.9-0.6-0.5
Latency to leave start box in cocaine runway, F0.30.30.70.70.4-0.40.5-0.5-0.1-0.8-0.30.80.80.60.8-0.8-0.4-0.30.10.70.4-0.70.70.7-0.70.7-0.20.6-0.2-0.1
Latency to leave start box in cocaine runway, M1.01.02.00.70.3-0.30.5-0.6-0.9-1.1-0.21.21.30.61.2-1.2-1.0-1.00.80.91.2-1.11.11.4-1.41.4-0.91.3-0.8-0.7
Std. dev. time between licks in bursts1.01.23.31.61.8-1.81.7-1.7-0.3-1.1-1.81.10.41.40.9-0.90.90.8-1.41.2-0.2-0.60.60.2-0.40.40.9-0.30.70.8
Total sessions with >9 infusions0.80.911.0-1.0-1.01.0-0.70.73.30.70.7-0.7-0.2-1.3-0.60.6-0.2-0.30.9-0.80.60.3-0.3-0.10.1-0.1-0.80.1-1.0-1.2
Short access day 1 total inactive lever presses0.30.34.2-0.2-0.40.4-0.10.22.00.6-0.0-0.6-0.5-0.7-0.70.7-0.00.30.2-0.40.00.5-0.5-0.40.4-0.40.0-0.4-0.40.0
Short access day 10 total inactive lever presses0.70.81.5-1.0-0.80.8-1.01.00.41.20.7-1.2-1.1-0.6-1.01.00.10.5-0.1-1.1-0.81.2-1.2-1.11.2-1.20.4-0.80.30.5
Short access day 1 total infusions0.70.88.6-0.8-1.01.0-0.70.72.90.80.7-0.8-0.2-1.4-0.40.4-0.4-0.41.1-0.70.30.3-0.3-0.20.2-0.2-0.60.0-0.9-0.6
Short access day 10 total infusions0.60.79.8-0.5-0.30.3-0.20.23.10.9-0.1-0.9-0.6-1.7-0.10.10.70.60.2-0.5-0.30.6-0.6-0.60.5-0.40.1-0.6-0.4-0.1
Short access total infusions0.50.67.9-0.3-0.70.7-0.30.32.80.10.4-0.10.4-0.90.1-0.1-0.5-0.61.1-0.30.8-0.20.10.4-0.40.4-0.90.5-1.1-0.9
Short access day 1 locomotion0.80.96.4-1.1-0.90.9-0.91.02.50.50.8-0.5-0.0-0.7-1.01.0-0.8-0.91.2-1.10.60.5-0.50.10.1-0.1-1.10.3-1.3-1.2
Short access day 10 total locomotion0.30.31.1-0.7-1.01.0-0.60.60.30.50.8-0.5-0.1-0.7-0.60.6-0.2-0.60.8-0.20.70.1-0.10.10.1-0.1-0.60.3-0.4-0.9
Short access total locomotion1.81.94.9-1.5-2.02.0-1.51.52.10.51.8-0.50.5-1.2-0.80.8-1.5-1.82.2-0.91.60.1-0.10.6-0.30.3-1.81.1-1.7-1.8
One hour access (0.3 mA shock)0.50.54.80.70.7-0.71.1-1.12.2-0.5-0.90.50.30.20.8-0.80.40.5-0.20.90.2-0.60.60.3-0.50.5-0.00.0-0.5-0.2
Compulsive drug intake0.60.62.10.5-0.30.30.4-0.4-0.1-0.9-0.10.91.00.61.0-1.0-0.6-0.70.40.51.5-0.60.61.0-1.01.0-0.81.0-0.8-1.0
One hour access (shock baseline)0.40.41.20.30.8-0.80.5-0.51.10.2-0.7-0.2-0.6-0.0-0.40.40.91.0-0.70.3-1.00.2-0.2-0.60.5-0.40.8-0.80.51.0
Social response proportion0.70.81.80.1-0.20.20.2-0.3-0.3-0.80.20.81.00.50.7-0.7-1.0-1.10.60.91.2-1.11.11.1-1.01.0-1.31.1-1.3-1.3
Social responses0.20.31.0-0.4-0.50.5-0.30.3-0.5-0.30.60.30.50.60.1-0.1-1.0-0.70.50.00.6-0.20.20.4-0.30.3-0.90.6-1.0-0.9
Social time1.01.32.80.4-0.40.40.3-0.4-0.2-1.10.31.11.40.71.2-1.2-1.4-1.21.11.11.7-1.31.31.4-1.41.3-1.41.5-1.5-1.4
Soleus weight1.02.96.30.6-0.90.90.1-0.2-1.9-1.60.71.72.21.41.1-1.1-2.5-2.42.01.52.5-2.12.12.1-1.91.9-1.82.3-1.5-1.4
Bone: stiffness1.11.84.4-2.1-1.81.8-1.91.91.51.31.9-1.3-0.5-1.5-1.41.4-1.1-1.01.6-1.30.40.8-0.8-0.30.5-0.5-1.30.2-1.3-1.4
Tibialis anterior weight0.41.32.60.5-0.40.40.2-0.3-1.2-1.00.31.11.50.91.1-1.1-1.6-1.51.41.11.6-1.41.41.4-1.41.4-1.21.5-1.2-0.9
Time to tail flick, vehicle, before self-admin0.60.62.30.3-0.60.6-0.0-0.1-1.5-0.80.40.81.01.10.4-0.4-0.8-0.90.60.61.1-0.80.80.9-0.80.7-0.81.0-0.7-0.9
Time to tail flick, vehicle, after self-admin1.92.15.4-1.3-2.12.1-1.51.41.40.62.0-0.50.8-1.4-0.20.2-2.1-2.02.3-0.01.5-0.60.60.7-0.50.5-2.11.3-2.1-2.1
Time to tail flick, test, before self-admin0.50.51.40.80.9-0.90.7-0.7-0.5-0.2-1.00.1-0.50.6-0.30.31.11.1-1.20.2-0.70.2-0.2-0.50.4-0.41.1-0.81.01.1
Time to tail flick, test, after self-admin0.40.41.2-0.8-0.80.8-0.60.71.00.80.5-0.8-0.7-1.1-1.01.0-0.1-0.10.4-0.70.20.6-0.6-0.50.6-0.6-0.1-0.3-0.1-0.2
Delta time to tail flick, vehicle, before/after SA0.20.21.7-0.0-0.00.00.2-0.21.30.1-0.2-0.00.2-0.80.5-0.5-0.2-0.20.30.50.3-0.50.50.2-0.30.3-0.30.1-0.4-0.3
Delta time to tail flick, test, before/after SA1.41.33.0-1.5-1.71.7-1.51.51.50.91.6-0.9-0.1-1.4-0.70.7-1.2-1.21.6-1.00.70.4-0.4-0.00.2-0.2-1.20.5-1.1-1.2
Tibia length8.624.347.4-6.9-5.15.1-6.56.63.46.55.2-6.4-5.6-5.7-6.76.70.50.31.4-6.4-2.65.6-5.6-4.75.2-5.30.2-2.80.10.2
Ambulatory time before self-admin1.81.83.6-1.4-1.11.1-1.61.6-0.61.71.1-1.7-1.5-1.2-1.51.50.90.5-0.1-1.9-0.81.9-1.9-1.51.6-1.70.8-1.11.01.0
Ambulatory time after self-admin0.50.61.81.21.4-1.41.2-1.20.0-0.7-1.20.60.10.50.8-0.80.70.9-0.80.6-0.4-0.30.30.2-0.30.40.8-0.30.70.7
Bone: tissue strength1.01.01.91.30.5-0.51.0-1.00.3-1.2-0.51.21.40.41.4-1.4-0.6-0.70.51.31.0-1.31.31.3-1.31.4-0.40.9-0.2-0.1
Total heroin consumption0.70.94.3-0.5-0.70.7-0.80.80.41.60.6-1.5-1.0-2.1-1.21.20.30.20.5-0.6-0.90.5-0.5-1.01.0-1.00.6-0.90.80.8
Bone: trabecular number0.81.22.61.21.5-1.51.3-1.2-1.3-0.4-1.60.3-0.41.10.4-0.41.41.4-1.60.4-1.10.2-0.2-0.40.3-0.31.5-1.01.51.5
Bone: trabecular spacing0.20.31.4-0.7-0.60.6-0.60.61.20.40.7-0.4-0.1-0.9-0.20.2-0.4-0.30.5-0.30.20.1-0.1-0.20.1-0.1-0.60.2-0.8-0.7
Bone: trabecular thickness0.60.71.81.31.2-1.21.3-1.3-1.2-0.8-1.30.80.41.10.8-0.80.50.5-0.71.0-0.0-0.60.60.4-0.50.50.6-0.20.70.7
Bone: trabecular tissue density0.30.41.2-1.1-1.01.0-0.90.90.00.40.9-0.4-0.3-0.6-0.80.8-0.6-0.70.7-0.60.40.2-0.3-0.10.2-0.3-0.80.4-0.9-0.8
Water consumed over 24 hours0.30.41.70.60.5-0.50.3-0.3-1.3-0.2-0.40.2-0.20.80.2-0.20.70.7-0.90.0-0.70.2-0.2-0.30.3-0.31.0-0.41.31.3
Number of responses in last shaping day1.31.32.8-1.7-1.71.7-1.61.6-0.01.31.4-1.3-0.8-1.4-1.41.4-1.0-0.61.5-1.40.30.9-0.9-0.60.8-0.8-0.6-0.1-0.6-0.5