Thra

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	mRNA stability	Thra	0.03	0.02	5.3e-04	0.02	0.02	0.01	0.01	4.0e-03	2.9e-03	5.2e-02	4.0e-02
2	BLA	gene expression	Thra	0.06	0.04	5.9e-03	0.01	-0	-0	-0	8.8e-02	3.5e-01	9.8e-01	6.1e-01
3	Adipose	alternative polyA	NM_001017960.2	0.02	0.01	6.6e-03	0.01	0.01	0	0.01	3.4e-02	5.0e-02	1.3e-01	4.8e-02
4	Adipose	alternative polyA	NM_031134.2	0.02	0.01	7.7e-03	0.01	0.01	0	0	4.6e-02	7.1e-02	1.7e-01	7.2e-02
5	PL	intron excision ratio	chr10_83724852_83728685	0.05	0.04	1.1e-03	0.01	0	0.01	0	6.9e-02	1.8e-01	7.3e-02	2.2e-01
6	Liver	gene expression	Thra	0.03	0.03	7.4e-04	0.01	0.01	0.01	0	3.9e-02	1.2e-02	5.3e-02	1.0e-01
7	PL	mRNA stability	Thra	0.32	0.14	1.2e-05	0.03	0.04	0.03	0.03	7.9e-04	3.6e-05	2.0e-04	2.1e-04
8	PL	intron excision ratio	chr10_83724852_83728568	0.05	0.04	1.2e-03	0	0	0	0	1.3e-01	2.3e-01	9.5e-02	2.2e-01
9	Brain	gene expression	Thra	0.12	0.07	9.8e-09	0.07	0.08	0.08	0.07	1.9e-07	5.5e-08	1.0e-07	1.9e-07
10	RMTg	isoform ratio	NM_031134.2	0.26	0.17	9.8e-03	0.03	-0	-0.01	0	5.5e-02	4.5e-01	7.3e-01	3.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	2.2	3.7	5.4	-2.1	-2.0	-2.3	2.3	2.0	2.1	-1.3	-2.1	1.9	-0.8
Area under the delay curve	0.2	0.2	0.5	-0.5	-0.7	-0.7	0.7	0.4	0.4	0.1	-0.2	0.1	0.4
BMI with tail	1.5	4.8	8.3	2.9	2.2	2.2	-2.2	-2.8	-2.3	2.7	1.1	-1.3	-1.4
BMI without tail	0.1	0.1	0.3	0.4	0.0	-0.2	0.2	-0.6	-0.4	0.5	0.2	-0.3	-0.1
Body weight	3.5	14.5	24.8	5.0	4.5	4.1	-4.1	-4.6	-4.1	3.9	2.2	-2.4	-1.8
Weight adjusted by age	0.8	0.9	3.1	0.4	0.8	0.8	-0.8	-0.2	-0.0	1.6	-0.9	0.5	-1.8
Bone surface	0.2	0.4	1.5	-0.1	-0.4	-0.6	0.6	0.1	0.4	0.1	-0.9	0.8	-1.2
Bone volume	0.6	1.0	2.7	-0.4	-0.6	-0.9	0.9	0.4	0.9	-0.2	-1.4	1.3	-1.7
Breakpoint value in progressive ratio session	0.2	0.2	0.9	-0.1	0.2	0.5	-0.5	0.4	0.2	-0.9	-0.4	0.6	-0.3
Number of licking bursts	0.5	0.5	1.6	-0.4	-0.2	-0.1	0.1	0.6	0.8	0.5	-1.1	1.0	-1.2
Context. condit. distance diff. score	2.4	2.9	5.3	1.3	1.4	1.4	-1.4	-1.6	-1.7	0.9	2.3	-2.3	2.1
Locomotion velocity, session 1	0.3	0.3	0.9	0.7	0.5	0.6	-0.6	-0.6	-0.5	0.5	-0.1	-0.0	-1.0
Locomotion distance, session 1	1.3	1.6	3.4	1.8	1.1	1.4	-1.4	-1.5	-1.3	1.3	0.4	-0.5	-1.4
Locomotion velocity, session 2	0.1	0.1	0.2	0.4	0.2	0.3	-0.3	-0.3	-0.4	0.1	0.1	-0.3	-0.0
Locomotion distance, session 2	0.4	0.5	3.0	0.4	-0.3	0.1	-0.1	-0.0	0.1	0.2	-1.0	0.8	-1.7
Locomotion velocity, session 3	0.1	0.2	0.4	-0.2	0.0	-0.6	0.6	0.3	-0.1	-0.6	-0.0	-0.1	0.6
Locomotion distance, session 3	0.1	0.1	0.2	0.4	0.5	0.1	-0.1	-0.3	-0.4	0.4	0.1	-0.2	-0.1
Stereotopy head waving bouts, day 3	1.9	2.2	3.9	-1.8	-1.6	-2.0	2.0	1.5	1.5	-1.5	-0.8	0.8	0.8
Stereotopy head waving duration, day 3	0.1	0.1	0.4	-0.3	-0.3	-0.6	0.6	0.1	0.2	-0.3	-0.0	-0.0	0.3
Locomotion velocity, session 7	0.8	0.9	2.2	1.1	1.0	1.1	-1.1	-0.8	-0.8	1.5	0.1	-0.3	-1.0
Locomotion distance, session 7	0.4	0.5	1.0	0.7	0.3	1.0	-1.0	-0.6	-0.6	1.0	0.5	-0.5	-0.3
Stereotopy head waving bouts, day 7	0.6	0.7	1.6	-0.8	-0.6	-1.3	1.3	0.7	0.8	-0.1	-0.8	0.7	-0.3
Stereotopy head waving duration, day 7	0.4	0.5	1.2	-0.6	-0.3	-1.1	1.1	0.6	0.6	-0.2	-0.7	0.6	-0.3
Locomotion velocity, session 8	6.5	7.8	10.3	3.2	2.9	3.1	-3.1	-3.1	-3.1	2.4	2.7	-2.7	0.5
Locomotion distance, session 8	1.0	1.4	2.2	1.5	1.2	1.4	-1.4	-1.4	-1.3	1.2	0.8	-1.0	-0.1
Degree of sensitization distance	1.3	1.4	2.5	1.2	0.8	1.6	-1.6	-1.2	-1.1	1.0	1.2	-1.1	0.3
Degree of sensitization stereotypy	0.9	1.0	1.5	-1.0	-0.7	-1.2	1.2	1.0	1.1	-0.1	-1.2	1.0	-0.7
Conditioned locomotion	0.1	0.1	0.4	-0.5	-0.7	-0.2	0.2	0.5	0.2	-0.2	0.0	0.0	0.5
Cocaine response after cond. corrected	1.1	1.2	2.5	-0.9	-1.1	-0.6	0.6	0.9	1.3	0.5	-1.5	1.4	-1.6
Cocaine response after cond. not corrected	1.3	1.4	2.6	-1.1	-1.2	-0.5	0.5	1.0	1.5	0.5	-1.6	1.5	-1.6
Cocaine response before conditioning	0.0	0.1	0.2	-0.4	-0.2	-0.1	0.1	0.2	0.2	-0.1	0.2	-0.1	0.5
Saline control response	0.3	0.4	1.6	0.4	0.1	0.8	-0.8	-0.4	-0.1	1.2	-0.0	-0.0	-0.8
Bone: connectivity density	3.0	4.7	6.9	-2.4	-2.4	-2.6	2.6	2.4	2.3	-1.6	-2.1	2.0	-0.5
Bone: cortical apparent density	4.6	6.1	9.2	-3.0	-3.0	-2.8	2.8	2.6	2.4	-3.0	-1.2	1.3	1.5
Bone: cortical area	0.0	0.0	0.1	-0.3	-0.3	-0.1	0.1	0.2	0.3	0.2	-0.2	0.2	0.1
Bone: cortical porosity	0.4	0.4	1.5	-0.3	-0.5	0.0	-0.0	0.4	0.6	0.3	-0.9	0.8	-1.2
Bone: cortical porosity	0.4	0.5	2.0	-0.2	-0.4	0.2	-0.2	0.3	0.6	0.6	-0.9	0.8	-1.4
Bone: cortical thickness	0.6	1.0	1.9	-1.4	-1.2	-1.0	1.0	1.1	1.1	-0.7	-0.4	0.4	1.0
Bone: cortical thickness	3.9	4.5	6.7	-2.6	-2.3	-2.3	2.3	2.6	2.2	-2.4	-1.4	1.5	1.0
Bone: cortical tissue density	4.6	6.1	9.2	-3.0	-3.0	-2.8	2.8	2.6	2.4	-3.0	-1.2	1.3	1.5
Condit. Reinf. active minus inactive responses	0.8	0.9	1.3	-1.1	-1.0	-1.0	1.0	1.1	0.8	-1.1	-0.3	0.4	0.9
Condit. Reinf. active-inactive response ratio	0.9	1.0	2.5	-1.2	-0.9	-1.0	1.0	1.1	0.7	-1.2	0.0	0.0	1.6
Condit. Reinf. active responses	0.6	0.8	1.3	-1.1	-1.0	-0.9	0.9	1.1	0.9	-0.9	-0.5	0.5	0.7
Condit. Reinf. inactive responses	0.2	0.2	0.6	-0.4	-0.2	-0.1	0.1	0.4	0.6	0.2	-0.8	0.7	-0.7
Incentive salience index mean	1.6	1.9	2.8	-1.7	-1.7	-1.5	1.5	1.6	1.4	-1.5	-1.0	1.0	0.5
Condit. Reinf. lever presses	0.9	1.2	2.2	-1.2	-1.5	-1.0	1.0	1.1	1.2	-0.8	-1.0	1.1	-0.2
Condit. Reinf. active minus inactive responses	1.2	1.5	2.1	-1.2	-0.8	-1.3	1.3	1.4	1.3	-1.3	-1.3	1.4	-0.6
Condit. Reinf. active-inactive response ratio	1.3	1.4	2.0	-1.0	-0.9	-1.3	1.3	1.2	1.2	-1.2	-1.4	1.4	-0.9
Condit. Reinf. active responses	2.1	2.9	4.3	-1.6	-1.2	-1.8	1.8	1.9	1.8	-1.5	-2.1	2.0	-1.1
Condit. Reinf. inactive responses	2.0	2.5	3.8	-1.6	-1.4	-1.6	1.6	1.7	1.8	-0.9	-2.0	1.7	-1.0
Condit. Reinf. lever presses	0.1	0.1	0.3	-0.4	-0.1	-0.5	0.5	0.5	0.3	-0.3	-0.4	0.2	0.3
Condit. Reinf. lever reinforcers received	2.0	2.8	3.6	-1.6	-1.3	-1.8	1.8	1.9	1.8	-1.6	-1.9	1.8	-0.7
Conditioned reinforcement - actives	0.3	0.3	0.9	-1.0	-0.6	0.2	-0.2	0.9	0.8	-0.5	-0.1	0.5	0.2
Conditioned reinforcement - inactives	1.7	2.0	6.7	-1.5	-1.5	-1.3	1.3	1.4	1.3	-2.6	-0.2	0.8	0.9
Conditioned locomotion	0.3	0.4	0.8	-0.9	-0.7	-0.2	0.2	0.8	0.9	-0.0	-0.6	0.8	-0.6
Patch foraging indifference point 0 sec	1.5	2.4	4.6	-1.9	-2.2	-1.9	1.9	1.6	1.4	-1.8	-0.4	0.6	1.1
Patch foraging indifference point AUC	0.1	0.1	0.8	0.2	-0.1	0.2	-0.2	0.1	-0.1	0.9	-0.3	-0.1	-0.4
Delay disc. indifference point, 0s delay	1.0	1.1	2.0	-1.1	-1.4	-1.4	1.4	1.0	1.1	-0.8	-0.8	0.8	0.1
Delay disc. indifference point, 16s delay	0.5	0.5	2.8	-0.5	-0.8	-0.3	0.3	0.2	0.1	-0.3	0.4	-0.7	1.7
Delay disc. indifference point, 2s delay	1.0	1.2	1.9	-1.1	-1.4	-1.1	1.1	1.0	1.3	-0.1	-1.1	1.2	-0.8
Delay disc. indifference point, 24s delay	0.2	0.2	0.6	0.1	0.1	0.1	-0.1	-0.3	-0.3	0.5	0.7	-0.7	0.8
Delay disc. indifference point, 4s delay	0.5	0.6	1.0	-0.9	-0.9	-0.6	0.6	0.9	1.0	-0.2	-1.0	0.8	-0.1
Delay disc. indifference point, 8s delay	0.1	0.1	0.4	-0.4	-0.4	-0.6	0.6	0.2	0.3	0.4	-0.2	0.1	0.1
Indifference point function ln k	0.2	0.3	1.8	-0.0	0.0	-0.1	0.1	-0.4	-0.3	-0.1	0.8	-0.8	1.4
Indifference point function log k	0.2	0.3	1.8	-0.0	0.0	-0.1	0.1	-0.4	-0.3	-0.1	0.8	-0.8	1.4
Patch foraging total patch changes 0 sec	1.1	1.8	3.8	-1.6	-2.0	-1.7	1.7	1.3	1.1	-1.4	-0.2	0.4	1.0
Patch foraging total patch changes 12 sec	5.1	6.6	8.8	-2.8	-3.0	-2.8	2.8	3.0	2.8	-2.1	-2.5	2.5	-0.8
Patch foraging total patch changes 18 sec	0.5	0.6	1.1	-0.9	-1.0	-1.1	1.1	0.9	0.8	-0.2	-0.7	0.5	0.0
Patch foraging total patch changes 24 sec	1.1	1.4	2.3	-1.5	-1.5	-1.3	1.3	1.5	1.3	-0.2	-1.2	0.9	-0.0
Patch foraging total patch changes 6 sec	2.1	3.1	5.5	-1.9	-2.3	-2.2	2.2	1.8	1.7	-1.7	-1.1	1.2	0.2
Patch foraging time to switch 0 sec	0.1	0.2	0.3	-0.4	-0.2	-0.5	0.5	0.5	0.4	-0.4	-0.6	0.6	-0.6
Patch foraging water rate 0 sec	0.1	0.1	0.4	-0.2	-0.5	-0.4	0.4	0.2	0.1	-0.6	0.1	0.1	0.5
Patch foraging water rate 12 sec	0.2	0.3	1.3	0.2	0.5	1.1	-1.1	-0.1	-0.3	-0.0	0.4	-0.2	0.5
Patch foraging water rate 18 sec	0.5	0.7	1.3	-0.8	-0.8	-0.5	0.5	0.8	1.0	-0.5	-1.1	1.1	-0.6
Patch foraging water rate 24 sec	0.7	0.9	2.9	-0.9	-1.0	-1.0	1.0	0.8	0.9	-1.7	-0.5	0.8	0.2
Patch foraging water rate 6 sec	1.4	2.0	3.4	-1.6	-1.8	-1.2	1.2	1.7	1.5	-1.7	-1.3	1.4	0.0
Seeking ratio, delayed vs. immediate footshock	1.0	1.2	5.3	-0.5	-0.8	0.9	-0.9	0.4	-0.0	-1.5	1.2	-0.7	2.3
Distance traveled before self-admin	0.3	0.3	0.8	0.1	0.1	0.9	-0.9	-0.1	0.1	-0.2	-0.4	0.5	-0.9
Distance traveled after self-admin	0.8	0.9	1.6	1.3	1.2	0.9	-0.9	-1.2	-1.1	0.8	0.4	-0.6	-0.5
Extensor digitorum longus weight	8.0	31.4	40.4	6.4	6.1	6.2	-6.2	-6.3	-6.2	5.0	5.3	-5.2	0.9
Bone: elastic displacement	0.0	0.0	0.2	0.0	0.0	-0.1	0.1	-0.1	-0.1	-0.1	0.2	-0.2	0.4
Bone: elastic work	0.1	0.2	0.3	-0.2	-0.3	-0.3	0.3	0.3	0.4	-0.4	-0.6	0.6	-0.4
Bone: endosteal estimation	1.5	3.2	5.3	2.3	2.0	1.9	-1.9	-2.1	-1.6	2.0	0.5	-0.6	-1.9
Bone: endosteal perimeter	0.9	1.8	3.1	1.8	1.6	1.6	-1.6	-1.6	-1.4	1.1	0.6	-0.7	-0.9
Epididymis fat weight	0.1	0.2	0.6	0.4	0.5	0.7	-0.7	-0.1	-0.1	-0.1	-0.2	0.4	-0.8
Delta time in closed arm before/after self-admin	2.3	2.3	4.5	2.1	1.9	0.9	-0.9	-1.9	-1.9	1.6	1.1	-1.3	-0.1
Delta time in open arm before/after self-admin	0.2	0.2	0.6	0.0	-0.0	0.8	-0.8	-0.2	-0.0	-0.2	0.4	-0.2	0.4
Diff in mean of infusions in LGA sessions	0.2	0.2	0.4	0.0	0.7	0.6	-0.6	0.3	0.1	-0.2	-0.3	0.4	-0.4
Delay discount exponential model param	0.1	0.1	0.3	0.3	0.4	0.5	-0.5	-0.2	-0.2	-0.2	0.1	0.0	-0.4
Extinction: sum of active levers before priming	1.4	1.4	3.5	1.4	1.3	1.2	-1.2	-1.4	-1.1	1.9	0.4	-0.7	-0.8
Active lever presses in extinction session 6	3.6	3.5	8.8	-1.2	-1.5	-1.0	1.0	1.3	1.8	-0.3	-3.0	2.5	-3.0
Bone: final force	0.8	1.3	2.9	-0.9	-1.0	-0.8	0.8	0.8	1.3	0.3	-1.7	1.5	-1.6
Bone: final moment	0.7	1.1	2.6	-0.7	-0.9	-0.7	0.7	0.6	1.1	0.4	-1.6	1.4	-1.6
Food consumed during 24 hour testing period	0.5	0.7	1.1	1.0	1.0	0.8	-0.8	-1.0	-0.9	0.6	0.7	-0.6	-0.1
Glucose	0.1	0.1	0.7	-0.2	-0.8	0.2	-0.2	0.0	0.4	0.5	-0.3	0.2	-0.2
Heart weight	2.7	3.8	7.1	2.4	1.9	1.8	-1.8	-2.7	-2.3	0.9	2.1	-2.0	0.5
Delay discount hyperbolic model param	0.2	0.2	0.4	0.5	0.6	0.6	-0.6	-0.3	-0.4	-0.2	0.2	-0.1	-0.4
Intermittent access intake day 1-15 change	0.6	0.6	1.2	-0.7	-0.6	-1.0	1.0	0.8	0.7	-1.1	-0.5	0.6	0.4
Intermittent access intake escalation	0.6	0.6	1.2	-0.7	-0.6	-0.9	0.9	0.8	0.7	-1.1	-0.6	0.7	0.2
Intermittent access intake escalation 2	0.1	0.1	0.2	-0.1	-0.0	-0.2	0.2	0.1	0.2	-0.4	-0.3	0.4	-0.2
Intermitt. access day 1 inactive lever presses	2.9	3.1	5.3	-1.5	-1.8	-2.3	2.3	1.6	1.5	-2.2	-1.7	1.5	-0.1
Intermitt. access day 15 inactive lever presses	4.2	4.6	7.2	-2.4	-2.3	-2.7	2.7	2.3	2.1	-2.5	-1.4	1.6	0.5
Intermitt. access escalation Index	2.3	2.0	5.1	1.4	2.0	1.3	-1.3	-1.5	-1.3	2.3	0.5	-1.1	-0.3
Intermittent access day 1 total infusions	0.2	0.2	0.5	-0.5	-0.4	-0.0	0.0	0.5	0.5	-0.7	-0.4	0.5	-0.2
Intermittent access day 15 total infusions	0.6	0.6	1.7	-0.8	-0.8	-0.8	0.8	0.9	0.8	-1.3	-0.5	0.5	0.6
Intermittent access terminal intake (last 3 days)	0.7	0.8	2.0	-0.9	-0.8	-0.8	0.8	1.0	0.9	-1.4	-0.7	0.8	0.2
Intermittent access total infusions	0.2	0.2	1.1	-0.5	-0.3	-0.2	0.2	0.5	0.5	-1.1	-0.3	0.4	0.2
Intermittent access day 1 locomotion	0.2	0.2	0.6	-0.5	-0.7	-0.3	0.3	0.4	0.4	-0.6	0.1	0.2	0.2
Intermittent access day 15 total locomotion	0.4	0.4	0.7	-0.7	-0.8	-0.8	0.8	0.5	0.7	-0.8	-0.1	0.5	-0.1
Intermittent access total locomotion	0.6	0.7	1.2	-1.0	-1.0	-0.9	0.9	1.0	0.8	-1.1	-0.2	0.6	0.4
Intermittent access standard deviation	2.2	2.3	6.0	-1.5	-1.3	-1.6	1.6	1.9	1.3	-2.5	-0.9	1.1	0.8
Left kidney weight	0.7	2.1	3.9	1.8	1.8	1.0	-1.0	-1.7	-2.0	0.9	1.2	-1.6	0.8
Right kidney weight	0.1	0.3	0.9	0.7	0.8	0.3	-0.3	-0.5	-0.4	0.6	-0.5	0.1	-1.0
Cocaine induced anxiety	1.5	1.8	3.6	1.6	1.9	0.9	-0.9	-1.5	-1.1	1.8	-0.3	-0.2	-1.8
Post-drug Anxiety	0.3	0.3	1.0	0.5	0.6	0.4	-0.4	-0.5	-0.2	1.0	-0.4	-0.0	-0.8
Baseline Anxiety	0.9	1.0	2.4	-1.4	-1.5	-0.6	0.6	1.2	0.9	-0.8	0.3	0.0	1.4
Tail length	0.1	0.4	0.8	0.7	0.9	0.7	-0.7	-0.5	-0.9	0.1	0.7	-0.7	0.5
Length with tail	1.9	7.0	11.1	3.3	3.3	3.0	-3.0	-2.9	-3.1	2.0	2.0	-2.1	0.1
Length without tail	2.6	5.8	9.1	3.0	3.0	3.0	-3.0	-2.6	-2.4	2.1	1.1	-1.3	-1.1
Times rat made contact with spout	0.9	1.1	1.6	-1.0	-0.9	-1.3	1.3	0.9	1.2	-1.0	-1.0	1.1	-0.6
Lifetime Intake	0.3	0.3	1.5	-0.5	-0.4	-0.3	0.3	0.6	0.5	-1.2	-0.4	0.5	0.3
Liver weight, left	0.0	0.1	0.1	-0.1	-0.1	0.0	-0.0	0.4	0.2	-0.3	-0.3	0.3	-0.1
Liver weight, right	0.5	0.8	1.6	-0.8	-0.9	-0.9	0.9	0.9	0.8	-0.9	-1.3	0.9	-0.3
Locomotor activity	0.8	1.2	2.7	-1.0	-0.6	-0.5	0.5	1.2	1.3	-0.2	-1.6	1.6	-1.4
Locomotor testing distance	1.7	2.9	4.7	-2.1	-1.7	-1.7	1.7	2.2	2.1	-0.9	-1.8	1.8	-0.5
Locomotor testing rearing	4.9	7.5	11.0	-3.3	-3.1	-3.3	3.3	3.2	2.8	-2.6	-1.9	1.9	0.9
Locomotion in novel chamber	4.1	5.0	9.8	-2.8	-3.1	-1.7	1.7	2.5	2.8	-1.8	-2.2	2.2	-0.4
Locomotion in novel chamber post-restriction	1.6	1.9	3.6	-1.2	-1.1	-1.1	1.1	1.1	1.6	-0.8	-1.7	1.9	-1.8
Fecal boli incidents, locomotor time 1	0.2	0.3	0.5	0.5	0.2	0.7	-0.7	-0.6	-0.4	0.4	0.6	-0.2	-0.4
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.1	-0.2	0.3	-0.3	-0.2	-0.1	0.5	0.2	-0.3	0.3
Time >=10cm from walls, locomotor time 1	0.2	0.2	1.0	-0.5	-0.6	-0.3	0.3	0.3	0.1	0.1	0.4	-0.5	1.0
Bouts of movement, locomotor time 1	0.4	0.4	1.6	0.7	1.1	-0.0	0.0	-0.4	-0.6	1.3	-0.4	-0.1	-0.7
Total resting periods, locomotor time 1	0.8	0.9	2.8	1.1	1.5	0.4	-0.4	-0.7	-0.9	1.7	-0.1	-0.2	-1.0
Rest time, locomotor task time 1	0.3	0.3	0.7	-0.1	0.1	-0.8	0.8	0.1	0.2	0.0	-0.6	0.6	-0.8
Distance moved, locomotor task time 1	0.1	0.1	0.3	-0.2	-0.6	0.2	-0.2	0.1	0.2	-0.3	0.1	-0.1	0.3
Vertical activity count, locomotor time 1	0.4	0.4	1.7	0.4	0.0	1.3	-1.3	-0.4	-0.3	0.3	0.5	-0.4	0.2
Time >=10cm from walls, locomotor time 2	0.7	0.8	1.6	-1.2	-1.3	0.2	-0.2	1.2	1.2	0.2	-0.8	0.8	-0.4
Bouts of movement, locomotor time 2	0.2	0.2	0.4	-0.5	-0.2	-0.7	0.7	0.6	0.2	0.1	-0.5	0.1	0.5
Total resting periods, locomotor time 2	0.1	0.1	0.5	-0.3	-0.0	-0.5	0.5	0.5	-0.0	0.1	-0.3	-0.1	0.7
Rest time, locomotor task time 2	0.5	0.5	1.0	1.0	0.9	0.7	-0.7	-0.8	-0.9	0.8	0.5	-0.5	-0.2
Distance moved, locomotor task time 2	0.1	0.1	0.2	0.3	-0.3	0.1	-0.1	-0.5	-0.1	0.5	-0.1	-0.2	-0.5
Vertical activity count, locomotor time 2	0.3	0.3	0.6	0.5	0.2	0.8	-0.8	-0.7	-0.5	0.6	0.6	-0.6	0.2
Light reinforcement 1	3.0	5.4	8.7	-2.4	-2.3	-3.0	3.0	2.6	2.3	-2.3	-2.0	2.0	-0.1
Light reinforcement 2	0.9	1.2	1.8	-0.8	-1.1	-1.4	1.4	0.9	1.1	-0.8	-1.2	1.3	-1.1
Bone: marrow area	1.4	2.9	4.9	2.2	1.9	1.8	-1.8	-2.0	-1.6	1.9	0.4	-0.6	-1.9
Bone: maximum diameter	0.1	0.1	0.4	-0.2	-0.2	-0.1	0.1	0.3	0.4	0.1	-0.6	0.5	-0.6
Bone: maximum force	0.2	0.3	1.3	0.2	-0.1	0.1	-0.1	-0.3	0.2	0.8	-0.6	0.4	-1.1
Bone: maximum moment	0.1	0.3	1.1	0.4	0.0	0.2	-0.2	-0.5	-0.0	0.9	-0.4	0.3	-1.0
Mean time between licks in bursts	0.8	1.1	2.8	1.4	1.7	0.9	-0.9	-1.3	-1.2	1.0	0.7	-0.7	-0.4
Mean num. licks in bursts	0.3	0.4	1.5	-0.3	-0.5	-0.8	0.8	0.1	0.1	-1.2	0.4	-0.1	0.8
Cd content in liver	0.2	0.2	0.5	-0.3	-0.3	-0.7	0.7	0.1	0.3	-0.4	-0.2	0.2	0.1
Co content in liver	0.6	0.7	1.0	0.9	1.0	0.6	-0.6	-0.8	-1.0	-0.3	1.0	-0.9	0.7
Cu content in liver	0.2	0.2	0.8	0.0	-0.2	-0.2	0.2	0.0	-0.3	-0.7	0.4	-0.4	0.9
Fe content in liver	0.6	0.7	1.3	1.2	1.1	0.9	-0.9	-0.9	-0.9	1.0	0.4	-0.4	-0.6
K content in liver	1.2	1.2	2.0	-1.3	-1.3	-1.0	1.0	1.4	1.2	-0.7	-1.2	1.1	-0.2
Mg content in liver	0.8	0.8	2.1	-1.2	-1.0	-0.7	0.7	1.2	0.7	-0.9	-0.1	0.0	1.5
Mn content in liver	1.9	2.1	3.3	-1.8	-1.6	-1.6	1.6	1.8	1.4	-1.6	-1.0	0.9	0.8
Na content in liver	0.9	1.0	3.1	-0.5	-0.7	-0.4	0.4	0.8	1.0	0.3	-1.5	1.4	-1.8
Rb content in liver	1.2	1.4	2.3	-1.4	-1.5	-1.5	1.5	1.3	1.2	-1.1	-0.8	0.7	0.5
Se content in liver	4.5	5.5	7.9	-2.8	-2.5	-2.5	2.5	2.8	2.4	-2.8	-1.9	2.0	0.3
Sr content in liver	0.2	0.2	0.9	-0.3	-0.2	0.0	-0.0	0.3	-0.0	-0.9	0.4	-0.2	1.0
Zn content in liver	3.1	3.4	6.4	-2.0	-1.8	-2.1	2.1	2.0	1.9	-2.5	-1.4	1.6	0.0
Bone: minimum diameter	0.4	0.7	1.2	1.0	0.8	1.1	-1.1	-1.0	-0.7	1.1	0.3	-0.4	-0.6
Time in familiar zone, hab. session 1	0.9	0.9	2.9	-0.3	-0.8	-0.6	0.6	0.3	0.9	-0.4	-1.2	1.3	-1.7
Time in novel zone, hab. session 1	0.8	0.8	3.4	-0.8	-0.7	-1.1	1.1	0.6	0.2	-0.6	0.4	-0.5	1.8
Total zone transitions, hab. session 1	1.4	1.9	2.8	1.7	1.6	1.4	-1.4	-1.6	-1.6	0.7	1.5	-1.4	0.4
Total locomotion distance, hab. session 1	0.1	0.2	0.7	0.1	0.3	-0.2	0.2	-0.2	-0.2	-0.8	0.6	-0.4	0.9
Locomotion velocity, hab. session 1	0.3	0.4	1.2	0.7	1.1	0.5	-0.5	-0.6	-0.7	-0.2	0.8	-0.6	0.6
Time in familiar zone, hab. session 2	0.7	0.7	1.0	-0.7	-1.0	-0.8	0.8	0.7	0.9	-0.8	-0.9	1.0	-0.7
Time in novel zone, hab. session 2	0.1	0.1	0.3	-0.5	-0.1	-0.5	0.5	0.5	0.2	-0.3	-0.1	-0.0	0.5
Total zone transitions, hab. session 2	0.7	1.0	1.5	1.2	0.6	1.2	-1.2	-1.2	-1.0	1.0	0.9	-0.8	-0.2
Total locomotion distance, hab. session 2	0.1	0.2	0.4	0.6	0.3	0.3	-0.3	-0.6	-0.3	0.1	0.2	-0.0	-0.5
Locomotion velocity, hab. session 2	0.3	0.3	0.7	0.8	0.6	0.6	-0.6	-0.8	-0.6	0.4	0.4	-0.2	-0.5
Novel to familiar place preference ratio	1.3	1.3	2.7	1.0	1.6	1.2	-1.2	-0.9	-1.2	1.1	1.2	-1.2	0.8
Novelty place preference	1.3	1.4	2.5	0.8	1.6	1.2	-1.2	-0.8	-1.2	1.0	1.3	-1.3	1.1
Time in novel zone, NPP test	0.7	0.7	1.3	0.4	1.2	0.7	-0.7	-0.4	-0.8	0.8	1.0	-1.0	1.1
Total zone transitions, NPP test	0.5	0.7	1.6	1.0	0.3	1.0	-1.0	-0.9	-0.5	0.8	0.1	-0.1	-1.3
Total locomotion distance, NPP test	0.1	0.1	0.8	0.2	-0.3	-0.2	0.2	-0.3	0.2	-0.1	-0.3	0.4	-0.9
Locomotion velocity, NPP test	0.2	0.3	0.8	0.8	0.4	0.4	-0.4	-0.9	-0.5	0.2	0.3	-0.2	-0.7
Intraocular pressure	2.3	3.2	4.1	2.0	1.9	1.9	-1.9	-2.0	-1.9	1.8	1.8	-1.6	0.0
Delta distance traveled before/after self-admin	1.1	1.2	1.9	1.3	1.3	0.7	-0.7	-1.2	-1.4	1.3	1.0	-1.3	0.5
Delta ambulatory time before/after self-admin	0.8	0.9	3.0	1.1	1.1	0.1	-0.1	-1.0	-1.1	1.7	0.4	-0.8	-0.3
Parametrial fat weight	2.1	4.2	6.5	-1.8	-1.4	-2.1	2.1	2.2	2.1	-2.0	-2.5	2.4	-1.4
Pavlov. Cond. lever latency	3.2	4.0	6.1	1.9	2.1	1.9	-1.9	-1.9	-2.3	1.3	2.5	-2.4	1.7
Pavlov. Cond. magazine entry latency	8.6	11.1	14.6	-3.7	-3.5	-3.5	3.5	3.6	3.8	-2.8	-3.4	3.4	-1.1
Pavlov. Cond. change in total contacts	7.1	7.6	10.6	-3.3	-3.2	-3.2	3.2	3.0	2.9	-3.0	-2.0	2.1	0.7
Pavlov. Cond. index score	7.5	9.5	12.5	-3.3	-3.3	-3.2	3.2	3.2	3.5	-2.4	-3.3	3.3	-1.5
Pavlov. Cond. latency score	5.8	7.4	9.9	-2.8	-2.9	-2.7	2.7	2.8	3.1	-2.0	-3.1	3.1	-1.6
Pavlov. Cond. lever contacts	2.8	3.2	5.2	-1.6	-1.8	-1.6	1.6	1.7	2.0	-1.1	-2.3	2.3	-1.7
Pavlov. Cond. magazine entry number	10.3	12.9	16.5	4.1	3.9	4.0	-4.0	-3.8	-4.0	3.3	3.4	-3.4	0.7
Pavlov. Cond. intertrial magazine entries	1.5	1.8	2.2	1.3	1.3	1.4	-1.4	-1.3	-1.5	1.2	1.5	-1.5	0.8
Pavlov. Cond. lever-magazine prob. diff.	8.1	10.0	13.1	-3.5	-3.4	-3.3	3.3	3.3	3.6	-2.6	-3.3	3.3	-1.2
Pavlov. Cond. response bias	7.8	9.4	12.2	-3.5	-3.4	-3.4	3.4	3.3	3.4	-2.8	-2.9	2.9	-0.6
Pavlov. Cond. lever latency	0.4	0.5	0.7	0.7	0.4	0.8	-0.8	-0.8	-0.8	0.6	0.8	-0.8	0.2
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	0.3	0.5	0.4	-0.4	-0.1	-0.1	0.2	0.0	0.1	-0.2
Pavlov. Cond. change in total contacts	0.5	0.7	1.1	-1.0	-0.9	-1.0	1.0	1.0	0.9	-1.0	-0.5	0.5	0.5
Pavlov. Cond. index score	0.2	0.3	0.4	-0.4	-0.3	-0.6	0.6	0.5	0.6	-0.4	-0.6	0.6	-0.4
Pavlov. Cond. latency score	0.1	0.1	0.3	-0.3	-0.1	-0.4	0.4	0.3	0.4	-0.2	-0.5	0.5	-0.3
Pavlov. Cond. lever contacts	0.9	1.2	1.9	-1.0	-0.8	-1.2	1.2	1.1	1.2	-0.7	-1.4	1.3	-0.7
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	0.1	0.2	0.3	-0.3	-0.1	-0.3	0.0	0.2	-0.3	0.2
Pavlov. Cond. intertrial magazine entries	1.9	2.5	3.5	1.3	1.8	1.6	-1.6	-1.3	-1.7	0.9	1.9	-1.9	1.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.3	-0.3	-0.1	-0.5	0.5	0.3	0.4	-0.3	-0.5	0.5	-0.3
Pavlov. Cond. response bias	1.1	1.6	2.2	-1.2	-1.1	-1.3	1.3	1.3	1.4	-0.9	-1.5	1.4	-0.6
Time in closed arm before self-admin	1.2	1.3	2.6	-1.1	-1.2	-1.6	1.6	0.8	0.6	-1.5	0.1	-0.0	1.4
Time in closed arm after self-admin	1.2	1.2	3.9	0.8	0.8	-0.1	0.1	-0.8	-1.2	0.1	1.4	-1.6	2.0
Time in open arm before self-admin	1.5	1.6	3.3	1.4	1.5	1.8	-1.8	-1.0	-1.1	1.4	0.4	-0.6	-0.6
Time in open arm after self-admin	0.7	0.7	2.6	0.7	0.6	1.6	-1.6	-0.5	-0.5	0.3	0.5	-0.3	-0.2
Bone: periosteal estimation	0.2	0.5	1.5	0.8	0.6	0.6	-0.6	-0.7	-0.4	0.9	-0.3	0.1	-1.2
Bone: periosteal perimeter	0.5	0.8	1.3	1.1	1.0	1.0	-1.0	-1.0	-0.7	0.9	0.1	-0.1	-1.1
Bone: post-yield work	1.2	1.7	2.9	1.5	1.3	1.2	-1.2	-1.7	-1.4	1.4	1.1	-1.2	-0.0
Progressive ratio test 1 active lever presses	0.3	0.3	0.7	-0.8	-0.7	-0.7	0.7	0.6	0.7	-0.2	-0.4	0.3	0.3
Progressive ratio test 1 breakpoint	0.3	0.3	0.5	-0.7	-0.6	-0.7	0.7	0.6	0.6	-0.1	-0.4	0.2	0.3
Progressive ratio test 1 inactive lever presses	1.7	1.9	3.8	-1.4	-1.3	-1.9	1.9	1.3	1.1	-1.7	-0.8	0.8	0.7
Progressive ratio test 2 active lever presses	0.9	0.9	2.0	-1.3	-1.1	-0.6	0.6	1.2	1.1	-1.4	-0.4	0.7	0.5
Progressive ratio test 2 breakpoint	0.6	0.6	1.3	-1.1	-0.9	-0.4	0.4	1.0	1.0	-1.1	-0.3	0.6	0.5
Progressive ratio test 2 inactive lever presses	0.6	0.7	3.0	-0.8	-0.9	-0.7	0.7	0.8	0.8	-1.7	-0.3	0.6	0.3
Incentive Sensitization - Responses	1.1	1.1	3.3	-1.3	-1.3	-0.6	0.6	1.2	1.2	-1.8	-0.3	1.0	-0.0
Incentive Sensitization - Breakpoint	1.1	1.1	2.8	-1.3	-1.2	-0.6	0.6	1.2	1.2	-1.7	-0.4	1.0	-0.1
Sum of active levers in priming session hrs 5-6	0.5	0.4	1.2	-0.6	-0.8	-0.5	0.5	0.4	0.7	-0.1	-1.1	0.8	-0.7
Progressive ratio	0.3	0.4	1.0	-0.4	-0.7	0.2	-0.2	0.6	0.6	0.2	-0.9	0.8	-1.0
Food seeking constrained by brief footshock	0.5	0.7	1.4	-0.6	-0.5	-1.0	1.0	0.6	0.7	-0.1	-1.2	0.9	-1.0
Seeking ratio, punishment vs. effort	0.1	0.1	0.3	0.1	0.5	-0.5	0.5	-0.3	-0.2	0.1	0.3	-0.4	0.5
Retroperitoneal fat weight	0.0	0.1	0.2	0.4	0.2	-0.0	0.0	-0.4	-0.3	-0.1	-0.1	-0.0	-0.4
Reaction time number correct	0.7	1.0	2.4	1.1	1.2	1.5	-1.5	-1.0	-0.8	0.6	0.6	-0.5	-0.2
Reaction time mean minus median	0.2	0.3	0.7	0.6	0.8	0.2	-0.2	-0.5	-0.6	0.5	0.7	-0.5	0.0
Reaction time mean minus median AUC	0.0	0.0	0.1	0.0	0.3	-0.3	0.3	-0.1	-0.1	0.4	0.3	-0.2	0.0
Reaction time num false alarms	0.7	0.9	1.7	-0.8	-0.9	-0.8	0.8	0.8	1.1	-0.2	-1.3	1.2	-1.3
Reaction time num false alarms AUC	0.6	0.9	1.9	-0.7	-0.6	-0.7	0.7	0.8	1.0	-0.2	-1.3	1.3	-1.4
Reaction time trials correct on left	0.7	1.0	2.4	1.1	1.2	1.5	-1.5	-1.0	-0.8	0.6	0.6	-0.5	-0.2
Reaction time trials on left	0.7	0.9	2.3	1.0	1.1	1.5	-1.5	-1.0	-0.7	0.5	0.6	-0.4	-0.2
Reaction time mean	0.3	0.4	0.9	-0.6	0.1	-0.8	0.8	0.6	0.2	-1.0	0.1	0.0	0.9
Reaction time mean AUC	0.3	0.4	0.9	-0.5	0.1	-0.8	0.8	0.6	0.2	-1.0	0.1	-0.0	0.9
Median of all reaction times	0.8	1.2	2.8	-1.3	-0.5	-1.3	1.3	1.2	0.9	-1.7	-0.4	0.5	0.9
Reaction time omissions	1.1	1.5	1.9	-1.3	-1.1	-1.4	1.4	1.3	1.3	-1.4	-1.1	1.3	-0.4
Reaction time false alarm rate	1.0	1.4	2.0	-1.1	-1.1	-1.3	1.3	1.1	1.2	-0.4	-1.4	1.3	-1.1
Reaction time premature initiation rate	0.5	0.6	1.9	-0.8	-0.4	-0.5	0.5	1.1	0.9	-0.2	-1.4	1.0	-0.4
Reaction time premature initiations	0.1	0.2	0.5	0.1	0.5	0.5	-0.5	0.2	0.2	0.2	-0.7	0.4	-0.4
Std. dev. reaction times	0.0	0.1	0.2	-0.0	0.4	-0.4	0.4	0.0	-0.1	-0.1	0.1	-0.0	0.0
Reaction time trials completed	0.7	0.9	2.3	1.0	1.1	1.5	-1.5	-1.0	-0.7	0.5	0.6	-0.4	-0.2
Reaction time trials AUC	0.7	1.0	2.4	1.0	1.1	1.5	-1.5	-1.0	-0.7	0.5	0.7	-0.5	-0.0
Run reversals in cocaine runway, females	3.7	3.6	5.3	1.7	1.9	2.0	-2.0	-1.6	-2.0	0.7	2.1	-2.3	2.2
Run reversals in cocaine runway, males	0.3	0.3	0.7	-0.7	-0.9	-0.2	0.2	0.5	0.7	-0.7	-0.2	0.4	0.1
Latency to leave start box in cocaine runway	1.5	1.7	2.5	1.5	1.0	1.6	-1.6	-1.5	-1.4	0.2	1.4	-1.2	0.7
Latency to leave start box in cocaine runway, F	1.6	1.7	3.8	1.5	1.2	2.0	-2.0	-1.4	-1.2	0.8	0.9	-0.9	0.1
Latency to leave start box in cocaine runway, M	0.8	0.8	2.5	-0.3	-0.8	-1.1	1.1	0.1	-0.0	-1.6	0.6	-0.3	1.3
Std. dev. time between licks in bursts	0.1	0.1	0.4	0.2	0.3	-0.1	0.1	-0.1	-0.0	0.2	-0.4	0.3	-0.6
Total sessions with >9 infusions	0.7	0.8	1.4	-0.8	-0.9	-1.2	1.2	0.7	0.6	-0.9	-0.2	0.1	1.2
Short access day 1 total inactive lever presses	2.4	2.7	6.5	-1.6	-1.7	-1.9	1.9	1.6	1.5	-2.5	-1.0	1.2	0.4
Short access day 10 total inactive lever presses	0.1	0.1	0.4	0.3	0.3	-0.2	0.2	-0.1	-0.2	-0.6	-0.2	0.1	-0.1
Short access day 1 total infusions	0.8	0.9	2.9	-0.8	-1.1	-0.9	0.9	1.0	0.6	-1.7	-0.4	0.4	1.0
Short access day 10 total infusions	0.3	0.4	0.7	-0.7	-0.5	-0.4	0.4	0.6	0.7	-0.8	-0.7	0.7	-0.4
Short access total infusions	0.4	0.4	1.7	-0.5	-0.5	-0.4	0.4	0.7	0.4	-1.3	-0.4	0.3	0.8
Short access day 1 locomotion	4.0	4.3	7.6	-2.1	-2.2	-2.8	2.8	2.1	1.9	-2.5	-1.3	1.5	0.5
Short access day 10 total locomotion	1.2	1.3	2.3	-1.4	-1.5	-1.2	1.2	1.3	1.3	-0.8	-0.8	1.1	-0.5
Short access total locomotion	0.7	0.7	1.6	-0.7	-1.0	-0.9	0.9	0.7	0.4	-1.3	0.2	0.1	1.1
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.1	0.2	0.4	-0.4	0.2	-0.0	-0.2	0.2	-0.2	0.5
Compulsive drug intake	1.4	1.4	5.0	0.6	0.7	0.6	-0.6	-0.6	-1.0	0.2	1.8	-1.6	2.2
One hour access (shock baseline)	0.4	0.5	1.0	-0.6	-0.6	-0.3	0.3	0.7	0.8	-0.7	-1.0	1.0	-0.8
Social response proportion	0.4	0.4	1.0	0.7	0.3	0.5	-0.5	-0.9	-0.6	1.0	0.5	-0.7	0.1
Social responses	0.2	0.2	0.7	-0.1	-0.7	-0.3	0.3	0.1	0.4	0.0	-0.6	0.5	-0.9
Social time	0.4	0.5	3.5	0.3	0.3	0.1	-0.1	-0.0	0.3	0.3	-0.8	0.9	-1.9
Soleus weight	0.3	0.9	4.6	0.1	-0.1	0.1	-0.1	-0.2	0.5	1.5	-1.0	0.9	-2.2
Bone: stiffness	0.1	0.1	0.7	0.1	0.0	0.1	-0.1	-0.2	0.2	0.6	-0.4	0.3	-0.8
Tibialis anterior weight	1.1	3.8	5.8	2.4	2.2	2.2	-2.2	-2.3	-2.0	2.1	1.3	-1.3	-0.9
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.4	-0.1	-0.1	-0.6	0.6	-0.1	0.2	-0.6	0.4	0.1	0.0
Time to tail flick, vehicle, after self-admin	0.2	0.3	1.2	-0.3	-0.3	-0.2	0.2	0.3	0.4	0.3	-0.6	0.7	-1.1
Time to tail flick, test, before self-admin	1.1	1.1	2.2	1.2	1.5	1.1	-1.1	-1.0	-1.1	1.4	0.8	-0.8	-0.2
Time to tail flick, test, after self-admin	0.4	0.4	0.9	-0.2	-0.9	-0.7	0.7	0.0	0.5	-0.9	-0.2	0.7	-0.8
Delta time to tail flick, vehicle, before/after SA	1.2	1.2	4.5	-0.5	-0.6	-0.3	0.3	0.7	0.9	0.6	-1.6	1.4	-2.1
Delta time to tail flick, test, before/after SA	2.3	2.1	4.8	-1.5	-2.2	-1.4	1.4	1.2	1.5	-2.0	-0.7	1.2	-0.2
Tibia length	1.2	3.5	5.8	2.3	2.2	1.9	-1.9	-2.3	-1.6	2.4	0.7	-0.8	-1.6
Ambulatory time before self-admin	0.2	0.2	0.6	0.2	0.3	0.8	-0.8	-0.2	-0.1	-0.5	0.1	0.1	-0.2
Ambulatory time after self-admin	1.2	1.3	2.8	1.7	1.7	0.7	-0.7	-1.6	-1.3	1.1	0.3	-0.6	-0.9
Bone: tissue strength	1.0	1.0	1.3	1.0	1.0	0.9	-0.9	-1.1	-1.0	1.1	1.0	-1.0	0.4
Total heroin consumption	2.8	3.2	6.1	-1.6	-1.3	-1.2	1.2	1.6	2.0	-1.8	-2.3	2.5	-2.1
Bone: trabecular number	5.1	7.9	9.9	-3.0	-3.1	-3.1	3.1	2.9	3.1	-1.9	-3.1	2.9	-1.4
Bone: trabecular spacing	1.3	1.7	2.6	1.6	1.4	1.6	-1.6	-1.5	-1.1	1.4	0.5	-0.5	-1.2
Bone: trabecular thickness	0.2	0.2	0.5	-0.3	-0.2	-0.7	0.7	0.3	0.4	-0.7	-0.3	0.4	-0.1
Bone: trabecular tissue density	0.5	0.8	4.0	-0.0	0.1	0.0	-0.0	-0.2	-0.6	-0.2	1.3	-1.3	2.0
Water consumed over 24 hours	0.0	0.1	0.2	0.3	0.3	0.1	-0.1	-0.5	-0.2	-0.1	0.3	-0.1	-0.1
Number of responses in last shaping day	0.9	0.9	2.8	-0.6	-0.9	-1.0	1.0	0.8	0.4	-1.7	0.1	0.1	1.4