Hub : Genes

Tgap1l7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr3_25676112_25676667 0.04 0.04 6.9e-05 0.01 0.02 0.03 0.02 2.9e-03 2.7e-04 8.3e-06 5.1e-04
2 BLA gene expression Tgap1l7 0.21 0.15 4.6e-04 0.03 0.04 0.04 0.03 1.4e-02 3.0e-03 5.7e-03 6.4e-03
3 PL intron excision ratio chr3_25676112_25676667 0.02 0.02 2.0e-03 0.02 0.02 0.01 0.02 1.5e-03 4.3e-03 1.1e-02 3.6e-03
4 PL gene expression Tgap1l7 0.06 0.04 1.4e-07 0.06 0.07 0.06 0.07 1.2e-07 9.5e-08 1.9e-07 7.2e-08
5 Adipose gene expression Tgap1l7 0.38 0.17 0.0e+00 0.37 0.36 0.36 0.36 1.1e-42 8.9e-42 7.3e-42 2.3e-42
6 Adipose intron excision ratio chr3_25690602_25698662 0.04 0.03 4.9e-05 0.03 0.03 0.03 0.03 1.0e-04 1.0e-04 1.3e-04 1.7e-04
7 LHb gene expression Tgap1l7 0.39 0.18 7.5e-10 0.4 0.36 0.36 0.39 1.3e-10 1.4e-09 1.9e-09 3.7e-10
8 OFC gene expression Tgap1l7 0.27 0.16 7.3e-06 0.21 0.18 0.16 0.2 1.2e-05 4.1e-05 1.5e-04 2.0e-05
9 PL intron excision ratio chr3_25670071_25676667 0.04 0.03 2.4e-05 0.04 0.04 0.04 0.04 1.0e-05 2.4e-05 3.0e-05 1.7e-05
10 Adipose intron excision ratio chr3_25684626_25686802 0.07 0.06 6.2e-07 0.04 0.05 0.05 0.05 5.8e-05 3.8e-06 3.4e-06 6.1e-06
11 IC gene expression Tgap1l7 0.07 0.06 1.5e-03 0.06 0.06 0.07 0.05 1.5e-03 2.4e-03 9.5e-04 3.1e-03
12 Brain intron excision ratio chr3_25701518_25702098 0.09 0.06 4.8e-08 0.06 0.07 0.07 0.07 4.1e-06 2.1e-07 4.1e-07 5.0e-07
13 Brain gene expression Tgap1l7 0.12 0.09 1.0e-08 0.06 0.08 0.08 0.07 1.7e-06 9.5e-08 5.8e-08 1.5e-07
14 NAcc intron excision ratio chr3_25670071_25676667 0.03 0.03 3.7e-04 0.01 0.01 0.01 0.01 7.0e-03 1.9e-03 8.7e-03 1.0e-02
15 IL gene expression Tgap1l7 0.14 0.11 1.5e-03 0.13 0.13 0.09 0.12 6.4e-04 6.2e-04 4.4e-03 9.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density3.45.86.92.41.62.62.62.6-2.62.62.6-2.62.02.6-2.11.9-2.22.4
Area under the delay curve0.50.61.3-1.01.10.60.60.6-0.60.60.6-0.61.00.6-0.91.1-0.90.7
BMI with tail0.10.40.60.2-0.6-0.7-0.7-0.70.7-0.7-0.70.7-0.8-0.70.4-0.50.5-0.4
BMI without tail0.30.88.73.0-1.1-0.2-0.2-0.20.2-0.2-0.20.2-1.0-0.10.5-0.90.5-0.2
Body weight0.20.93.71.9-1.3-0.7-0.8-0.80.8-0.8-0.80.8-1.3-0.60.8-1.00.8-0.6
Weight adjusted by age0.40.62.11.50.30.80.80.8-0.80.80.8-0.80.40.8-0.60.4-0.60.7
Bone surface3.35.96.61.22.42.52.52.5-2.52.52.5-2.52.52.5-2.52.6-2.52.5
Bone volume3.66.47.01.42.32.72.72.7-2.72.72.7-2.72.52.6-2.52.5-2.62.6
Breakpoint value in progressive ratio session1.51.82.11.11.21.21.51.5-1.51.51.5-1.51.21.4-1.31.2-1.31.4
Number of licking bursts3.15.17.2-2.7-1.3-2.6-2.6-2.62.6-2.6-2.62.6-1.7-2.41.8-1.51.8-2.0
Context. condit. distance diff. score0.20.33.1-1.80.4-0.3-0.3-0.30.3-0.3-0.30.30.4-0.30.10.10.1-0.3
Locomotion velocity, session 10.60.73.3-1.81.30.30.30.3-0.30.30.3-0.30.90.3-0.91.1-0.90.7
Locomotion distance, session 12.12.75.2-1.32.31.31.31.3-1.31.31.3-1.32.01.3-2.02.2-1.91.8
Locomotion velocity, session 20.70.91.2-0.00.61.11.11.1-1.11.11.1-1.10.91.1-0.80.6-0.80.9
Locomotion distance, session 21.11.62.2-0.41.51.21.21.2-1.21.21.2-1.21.41.2-1.41.4-1.41.4
Locomotion velocity, session 31.41.62.01.30.81.41.41.4-1.41.41.4-1.40.91.4-1.20.8-1.21.3
Locomotion distance, session 30.50.51.01.00.40.70.70.7-0.70.70.7-0.70.40.7-0.70.6-0.70.8
Stereotopy head waving bouts, day 31.31.53.40.2-1.6-1.0-1.0-1.01.0-1.0-1.01.0-1.5-1.01.4-1.81.4-1.3
Stereotopy head waving duration, day 30.50.61.60.4-1.1-0.6-0.6-0.60.6-0.6-0.60.6-1.0-0.60.9-1.30.9-0.8
Locomotion velocity, session 70.40.52.3-1.50.90.50.50.5-0.50.50.5-0.51.00.5-0.50.6-0.60.4
Locomotion distance, session 70.60.88.8-3.00.7-0.5-0.5-0.50.5-0.5-0.50.50.5-0.50.00.40.0-0.3
Stereotopy head waving bouts, day 70.60.74.02.0-1.4-0.0-0.0-0.00.0-0.0-0.00.0-0.90.10.8-1.30.8-0.5
Stereotopy head waving duration, day 70.60.75.52.3-1.40.10.10.1-0.10.10.1-0.1-0.90.20.8-1.20.7-0.4
Locomotion velocity, session 80.40.51.2-1.1-0.5-0.6-0.6-0.60.6-0.6-0.60.6-0.4-0.60.7-0.70.7-0.7
Locomotion distance, session 80.40.61.5-1.21.10.60.60.6-0.60.60.6-0.61.00.5-0.80.8-0.80.6
Degree of sensitization distance1.61.612.1-3.50.3-1.1-1.1-1.11.1-1.1-1.11.10.1-1.10.6-0.10.6-1.0
Degree of sensitization stereotypy0.60.65.82.4-0.70.60.60.6-0.60.60.6-0.6-0.20.60.1-0.50.10.2
Conditioned locomotion4.45.05.7-1.5-2.0-2.4-2.4-2.42.4-2.4-2.42.4-2.1-2.42.3-2.02.3-2.4
Cocaine response after cond. corrected1.21.42.0-0.2-0.9-1.4-1.4-1.41.4-1.4-1.41.4-1.1-1.41.0-0.81.1-1.1
Cocaine response after cond. not corrected0.30.40.70.2-0.4-0.8-0.8-0.80.8-0.8-0.80.8-0.6-0.80.4-0.30.5-0.5
Cocaine response before conditioning1.21.51.81.00.91.31.31.3-1.31.31.3-1.31.11.3-1.11.0-1.11.2
Saline control response0.20.30.40.4-0.5-0.6-0.6-0.60.6-0.6-0.60.6-0.7-0.70.5-0.30.5-0.5
Bone: connectivity density1.72.73.51.91.01.81.81.8-1.81.81.8-1.81.31.8-1.41.2-1.51.6
Bone: cortical apparent density0.91.22.30.0-1.5-0.9-0.9-0.90.9-0.9-0.90.9-1.3-0.91.4-1.51.4-1.3
Bone: cortical area0.60.91.10.70.71.01.01.0-1.01.01.0-1.00.81.0-0.91.0-0.91.0
Bone: cortical porosity2.83.03.70.0-1.9-1.8-1.8-1.81.8-1.8-1.81.8-1.9-1.71.9-1.61.9-1.8
Bone: cortical porosity2.12.32.6-0.2-1.5-1.6-1.6-1.61.6-1.6-1.61.6-1.6-1.61.6-1.21.6-1.6
Bone: cortical thickness0.30.53.11.8-0.10.70.70.7-0.70.70.7-0.70.00.7-0.40.3-0.40.6
Bone: cortical thickness0.10.10.80.9-0.6-0.1-0.1-0.10.1-0.1-0.10.1-0.5-0.10.4-0.30.3-0.2
Bone: cortical tissue density1.01.32.3-0.2-1.5-1.0-1.0-1.01.0-1.0-1.01.0-1.3-1.01.5-1.51.4-1.3
Condit. Reinf. active minus inactive responses1.01.14.7-2.2-0.2-1.1-1.1-1.11.1-1.1-1.11.1-0.3-1.10.8-0.30.8-1.0
Condit. Reinf. active-inactive response ratio1.61.76.7-2.6-0.3-1.3-1.3-1.31.3-1.3-1.31.3-0.5-1.31.0-0.51.0-1.2
Condit. Reinf. active responses0.30.42.2-1.50.2-0.6-0.6-0.60.6-0.6-0.60.60.1-0.60.30.20.3-0.5
Condit. Reinf. inactive responses0.50.60.80.60.80.70.70.7-0.70.70.7-0.70.80.7-0.80.9-0.80.8
Incentive salience index mean0.10.10.7-0.80.2-0.4-0.4-0.40.4-0.4-0.40.40.1-0.30.20.10.2-0.3
Condit. Reinf. lever presses1.01.44.72.20.61.21.21.2-1.21.21.2-1.20.91.2-0.90.9-1.01.1
Condit. Reinf. active minus inactive responses1.01.31.5-0.4-1.1-1.2-1.2-1.21.2-1.2-1.21.2-1.1-1.21.2-1.21.2-1.2
Condit. Reinf. active-inactive response ratio1.41.61.8-0.5-1.0-1.4-1.4-1.41.4-1.4-1.41.4-1.1-1.31.3-1.21.3-1.4
Condit. Reinf. active responses0.10.10.2-0.1-0.4-0.2-0.2-0.20.2-0.2-0.20.2-0.4-0.20.3-0.50.3-0.3
Condit. Reinf. inactive responses0.10.20.30.20.20.50.50.5-0.50.50.5-0.50.20.4-0.40.3-0.40.5
Condit. Reinf. lever presses0.60.91.10.60.91.01.01.0-1.01.01.0-1.00.90.9-1.00.9-1.01.0
Condit. Reinf. lever reinforcers received0.00.00.20.2-0.4-0.1-0.1-0.10.1-0.1-0.10.1-0.3-0.10.2-0.40.2-0.1
Conditioned reinforcement - actives0.40.71.0-0.5-0.7-1.0-1.0-1.01.0-1.0-1.01.0-0.8-0.90.8-0.60.8-0.8
Conditioned reinforcement - inactives0.60.95.8-2.41.6-0.1-0.1-0.10.1-0.1-0.10.11.1-0.0-0.91.5-0.80.5
Conditioned locomotion1.72.24.3-2.1-0.9-1.6-1.6-1.61.6-1.6-1.61.6-1.1-1.61.3-1.01.3-1.4
Patch foraging indifference point 0 sec0.71.42.00.71.31.11.01.0-1.01.01.0-1.01.21.2-1.41.3-1.41.4
Patch foraging indifference point AUC0.20.34.62.10.1-0.00.00.0-0.00.00.0-0.0-0.20.0-0.30.4-0.20.3
Delay disc. indifference point, 0s delay0.70.81.00.90.60.91.01.0-1.01.01.0-1.00.70.9-0.70.6-0.80.8
Delay disc. indifference point, 16s delay0.10.10.3-0.50.40.30.20.2-0.20.20.2-0.20.40.2-0.30.4-0.30.2
Delay disc. indifference point, 2s delay0.91.01.7-0.21.30.90.90.9-0.90.90.9-0.91.20.9-1.11.3-1.11.0
Delay disc. indifference point, 24s delay1.01.15.1-2.3-0.4-0.9-1.1-1.11.1-1.1-1.11.1-0.5-1.00.8-0.60.8-0.9
Delay disc. indifference point, 4s delay0.70.71.1-0.61.10.70.70.7-0.70.70.7-0.71.00.8-1.01.0-0.90.9
Delay disc. indifference point, 8s delay0.50.61.2-0.41.10.70.70.7-0.70.70.7-0.71.00.7-0.91.1-0.90.8
Indifference point function ln k0.71.21.7-0.01.21.21.11.1-1.11.11.1-1.11.31.1-1.11.1-1.11.0
Indifference point function log k0.71.21.7-0.01.21.21.11.1-1.11.11.1-1.11.31.1-1.11.1-1.11.0
Patch foraging total patch changes 0 sec0.71.32.00.31.41.01.01.0-1.01.01.0-1.01.21.2-1.41.3-1.41.4
Patch foraging total patch changes 12 sec1.11.42.11.01.31.11.11.1-1.11.11.1-1.11.21.2-1.41.5-1.41.4
Patch foraging total patch changes 18 sec0.00.00.60.8-0.2-0.0-0.0-0.00.0-0.0-0.00.0-0.20.0-0.0-0.00.00.1
Patch foraging total patch changes 24 sec0.30.53.41.90.10.60.50.5-0.50.50.5-0.50.10.7-0.60.3-0.60.7
Patch foraging total patch changes 6 sec0.10.20.6-0.30.80.00.10.1-0.10.10.1-0.10.50.1-0.60.8-0.50.4
Patch foraging time to switch 0 sec0.30.75.0-2.20.80.50.60.6-0.60.60.6-0.61.00.6-0.60.7-0.60.6
Patch foraging water rate 0 sec0.30.78.32.9-0.20.50.40.4-0.40.40.4-0.4-0.20.3-0.10.0-0.10.3
Patch foraging water rate 12 sec0.61.21.60.7-1.1-1.0-1.0-1.01.0-1.0-1.01.0-1.1-1.21.2-1.21.2-1.3
Patch foraging water rate 18 sec0.20.30.50.60.70.70.60.6-0.60.60.6-0.60.70.4-0.50.5-0.50.4
Patch foraging water rate 24 sec0.10.10.3-0.20.60.30.20.2-0.20.20.2-0.20.60.2-0.20.4-0.30.1
Patch foraging water rate 6 sec0.50.76.12.50.50.70.60.6-0.60.60.6-0.60.40.5-0.50.7-0.50.5
Seeking ratio, delayed vs. immediate footshock2.73.33.7-0.5-1.8-1.9-1.9-1.91.9-1.9-1.91.9-1.9-1.91.8-1.81.8-1.8
Distance traveled before self-admin0.20.31.11.00.20.60.50.5-0.50.50.5-0.50.30.6-0.40.2-0.40.5
Distance traveled after self-admin4.75.86.31.42.32.52.52.5-2.52.52.5-2.52.42.5-2.42.4-2.52.5
Extensor digitorum longus weight1.66.211.00.63.02.12.12.1-2.12.12.1-2.12.52.3-3.23.3-3.13.1
Bone: elastic displacement0.80.92.11.4-1.2-0.8-0.8-0.80.8-0.8-0.80.8-1.1-0.81.0-1.11.0-0.9
Bone: elastic work1.11.42.51.4-1.4-1.1-1.1-1.11.1-1.1-1.11.1-1.6-1.21.1-1.21.1-1.0
Bone: endosteal estimation0.20.43.5-1.90.9-0.1-0.1-0.10.1-0.1-0.10.10.7-0.1-0.30.7-0.30.1
Bone: endosteal perimeter0.30.62.8-1.70.3-0.9-0.9-0.90.9-0.9-0.90.9-0.2-0.90.10.10.2-0.4
Epididymis fat weight0.51.75.22.3-1.7-1.1-1.1-1.11.1-1.1-1.11.1-1.7-0.81.1-1.41.1-0.9
Delta time in closed arm before/after self-admin5.45.16.3-2.4-1.3-2.5-2.5-2.52.5-2.5-2.52.5-1.6-2.52.0-1.52.0-2.2
Delta time in open arm before/after self-admin1.31.38.73.0-0.21.11.11.1-1.11.11.1-1.10.11.1-0.50.1-0.50.8
Diff in mean of infusions in LGA sessions0.81.01.3-0.7-1.1-1.0-0.9-0.90.9-0.9-0.90.9-1.0-1.01.1-1.21.1-1.1
Delay discount exponential model param0.70.72.01.4-1.3-0.6-0.5-0.50.5-0.5-0.50.5-1.2-0.60.9-1.20.9-0.8
Extinction: sum of active levers before priming1.31.41.60.11.21.21.31.3-1.31.31.3-1.31.21.3-1.31.1-1.31.3
Active lever presses in extinction session 62.02.02.21.41.31.51.41.4-1.41.41.4-1.41.31.5-1.41.4-1.41.5
Bone: final force0.10.21.41.2-0.10.40.40.4-0.40.40.4-0.40.00.4-0.20.2-0.20.3
Bone: final moment0.20.31.21.10.10.60.60.6-0.60.60.6-0.60.20.6-0.40.4-0.40.5
Food consumed during 24 hour testing period0.40.51.7-1.21.30.30.30.3-0.30.30.3-0.31.10.6-0.90.9-0.90.7
Glucose0.10.22.3-1.50.3-0.1-0.0-0.00.0-0.0-0.00.00.4-0.20.10.20.1-0.2
Heart weight1.01.58.3-2.9-0.5-1.2-1.1-1.11.1-1.1-1.11.1-0.5-1.21.0-0.81.0-1.2
Delay discount hyperbolic model param0.70.81.81.3-1.3-0.6-0.6-0.60.6-0.6-0.60.6-1.2-0.61.0-1.20.9-0.8
Intermittent access intake day 1-15 change1.02.14.4-1.62.11.11.11.1-1.11.11.1-1.11.91.1-1.71.9-1.61.4
Intermittent access intake escalation0.61.22.6-1.61.60.80.80.8-0.80.80.8-0.81.50.8-1.21.4-1.21.0
Intermittent access intake escalation 22.42.73.7-0.31.91.61.61.6-1.61.61.6-1.61.91.6-1.81.9-1.81.7
Intermitt. access day 1 inactive lever presses0.10.20.8-0.50.90.10.10.1-0.10.10.1-0.10.70.1-0.50.8-0.50.3
Intermitt. access day 15 inactive lever presses0.71.52.8-1.21.71.01.01.0-1.01.01.0-1.01.51.0-1.41.5-1.41.2
Intermitt. access escalation Index0.60.81.0-0.7-0.7-1.0-1.0-1.01.0-1.0-1.01.0-0.8-1.00.9-0.80.9-1.0
Intermittent access day 1 total infusions0.00.10.1-0.10.1-0.3-0.3-0.30.3-0.3-0.30.3-0.0-0.30.00.40.0-0.1
Intermittent access day 15 total infusions0.50.77.6-2.80.9-0.3-0.3-0.30.3-0.3-0.30.30.6-0.3-0.30.7-0.30.0
Intermittent access terminal intake (last 3 days)0.70.910.8-3.31.0-0.4-0.4-0.40.4-0.4-0.40.40.7-0.4-0.30.8-0.30.0
Intermittent access total infusions0.60.75.8-2.40.4-0.7-0.7-0.70.7-0.7-0.70.70.1-0.70.10.20.2-0.4
Intermittent access day 1 locomotion1.82.32.8-1.4-1.0-1.7-1.7-1.71.7-1.7-1.71.7-1.2-1.71.4-1.11.4-1.5
Intermittent access day 15 total locomotion0.91.711.4-3.40.3-1.2-1.2-1.21.2-1.2-1.21.2-0.0-1.20.6-0.00.6-0.9
Intermittent access total locomotion1.51.810.6-3.30.0-1.4-1.4-1.41.4-1.4-1.41.4-0.3-1.40.7-0.20.7-1.0
Intermittent access standard deviation0.61.22.3-0.91.50.90.90.9-0.90.90.9-0.91.40.9-1.31.4-1.31.2
Left kidney weight0.31.35.12.3-1.6-0.7-0.8-0.80.8-0.8-0.80.8-1.5-0.61.2-1.41.1-0.9
Right kidney weight1.25.37.90.8-2.8-2.2-2.2-2.22.2-2.2-2.22.2-2.7-2.12.6-2.72.5-2.4
Cocaine induced anxiety0.10.10.80.9-0.30.10.10.1-0.10.10.1-0.1-0.30.10.1-0.30.1-0.0
Post-drug Anxiety0.10.20.2-0.20.20.50.50.5-0.50.50.5-0.50.30.5-0.3-0.1-0.30.4
Baseline Anxiety0.40.56.4-2.50.4-0.2-0.2-0.20.2-0.2-0.20.20.4-0.2-0.10.1-0.0-0.1
Tail length0.51.820.94.6-0.80.80.80.8-0.80.80.8-0.8-0.40.90.0-0.5-0.00.4
Length with tail0.20.87.52.7-1.0-0.5-0.5-0.50.5-0.5-0.50.5-1.1-0.30.5-0.60.5-0.3
Length without tail0.20.81.5-1.2-0.3-1.0-1.1-1.11.1-1.1-1.11.1-0.6-0.90.4-0.10.5-0.5
Times rat made contact with spout0.91.02.5-1.6-0.3-1.2-1.1-1.11.1-1.1-1.11.1-0.5-1.00.7-0.40.7-0.8
Lifetime Intake0.60.85.5-2.30.2-0.8-0.8-0.80.8-0.8-0.80.8-0.1-0.80.30.00.3-0.5
Liver weight, left0.30.50.80.2-0.9-0.5-0.7-0.70.7-0.7-0.70.7-0.8-0.50.7-0.80.7-0.6
Liver weight, right0.20.30.70.80.30.70.60.6-0.60.60.6-0.60.30.5-0.50.5-0.50.6
Locomotor activity0.91.31.70.7-1.2-1.3-1.2-1.21.2-1.2-1.21.2-1.3-1.21.1-1.11.1-1.1
Locomotor testing distance0.00.00.1-0.30.2-0.2-0.2-0.20.2-0.2-0.20.20.0-0.2-0.20.2-0.20.1
Locomotor testing rearing0.10.21.5-1.20.50.20.20.2-0.20.20.2-0.20.50.2-0.50.5-0.40.4
Locomotion in novel chamber0.70.91.00.30.91.01.01.0-1.01.01.0-1.01.01.0-1.00.9-1.01.0
Locomotion in novel chamber post-restriction0.20.30.7-0.90.70.40.40.4-0.40.40.4-0.40.70.4-0.50.6-0.50.4
Fecal boli incidents, locomotor time 10.10.10.3-0.50.60.10.10.1-0.10.10.1-0.10.40.2-0.40.5-0.40.4
Change in fecal boli incidents, locomotor task0.10.10.3-0.4-0.5-0.3-0.3-0.30.3-0.3-0.30.3-0.4-0.40.5-0.50.5-0.5
Time >=10cm from walls, locomotor time 10.40.44.5-2.10.4-0.3-0.3-0.30.3-0.3-0.30.30.3-0.30.00.20.0-0.2
Bouts of movement, locomotor time 10.30.30.5-0.70.10.60.70.7-0.70.70.7-0.70.20.6-0.4-0.0-0.40.5
Total resting periods, locomotor time 10.30.30.6-0.2-0.10.70.80.8-0.80.80.8-0.80.10.7-0.3-0.2-0.30.5
Rest time, locomotor task time 10.10.10.30.1-0.6-0.0-0.0-0.00.0-0.0-0.00.0-0.5-0.10.3-0.60.3-0.1
Distance moved, locomotor task time 10.81.22.1-0.31.41.21.01.0-1.01.01.0-1.01.41.0-1.11.4-1.10.9
Vertical activity count, locomotor time 10.20.54.1-2.01.10.10.00.0-0.00.00.0-0.00.90.1-0.51.0-0.50.2
Time >=10cm from walls, locomotor time 20.10.21.61.3-0.6-0.00.10.1-0.10.10.1-0.1-0.4-0.10.4-0.40.3-0.3
Bouts of movement, locomotor time 20.40.62.01.0-1.4-0.4-0.3-0.30.3-0.3-0.30.3-1.2-0.40.9-1.40.9-0.6
Total resting periods, locomotor time 20.20.31.20.4-1.1-0.3-0.3-0.30.3-0.3-0.30.3-0.9-0.30.7-1.10.7-0.5
Rest time, locomotor task time 20.00.00.1-0.40.10.10.00.0-0.00.00.0-0.00.10.1-0.20.1-0.20.2
Distance moved, locomotor task time 20.30.30.50.10.50.70.60.6-0.60.60.6-0.60.70.6-0.40.6-0.50.4
Vertical activity count, locomotor time 20.40.53.1-1.81.20.30.30.3-0.30.30.3-0.31.10.2-0.61.0-0.60.4
Light reinforcement 10.51.31.80.51.21.11.11.1-1.11.11.1-1.11.11.1-1.41.3-1.31.3
Light reinforcement 21.82.716.34.00.11.51.61.6-1.61.61.6-1.60.41.6-0.90.2-1.01.3
Bone: marrow area0.20.43.3-1.80.9-0.1-0.1-0.10.1-0.1-0.10.10.6-0.1-0.30.7-0.30.1
Bone: maximum diameter0.71.32.1-0.51.41.11.11.1-1.11.11.1-1.11.41.0-1.21.4-1.21.1
Bone: maximum force0.10.10.50.20.40.30.30.3-0.30.30.3-0.30.30.2-0.50.7-0.50.5
Bone: maximum moment0.20.30.70.20.60.50.50.5-0.50.50.5-0.50.50.4-0.70.9-0.70.7
Mean time between licks in bursts0.30.70.9-0.20.80.80.90.9-0.90.90.9-0.90.90.9-0.70.8-0.70.7
Mean num. licks in bursts2.13.24.01.11.42.02.02.0-2.02.02.0-2.01.71.9-1.61.5-1.61.7
Cd content in liver0.91.04.8-2.2-0.6-1.1-0.7-0.70.7-0.7-0.70.7-0.5-1.11.1-0.71.0-1.2
Co content in liver3.33.85.2-1.7-1.8-2.1-1.9-1.91.9-1.9-1.91.9-1.7-2.02.2-1.92.2-2.3
Cu content in liver0.10.10.50.3-0.7-0.4-0.1-0.10.1-0.1-0.10.1-0.6-0.30.5-0.60.5-0.4
Fe content in liver2.53.13.7-0.1-1.9-1.8-1.7-1.71.7-1.7-1.71.7-1.9-1.81.9-1.81.9-1.8
K content in liver0.80.83.01.7-0.20.91.11.1-1.11.11.1-1.10.20.9-0.3-0.2-0.30.5
Mg content in liver0.20.21.31.1-0.7-0.2-0.2-0.20.2-0.2-0.20.2-0.7-0.20.3-0.60.3-0.2
Mn content in liver2.02.24.00.3-2.0-1.4-1.3-1.31.3-1.3-1.31.3-1.8-1.41.7-2.01.7-1.6
Na content in liver0.60.73.21.8-0.30.71.01.0-1.01.01.0-1.00.10.8-0.2-0.2-0.20.4
Rb content in liver0.50.61.0-0.5-0.2-0.9-1.0-1.01.0-1.0-1.01.0-0.6-1.00.3-0.10.4-0.4
Se content in liver1.41.62.3-0.8-1.2-1.5-1.2-1.21.2-1.2-1.21.2-1.3-1.51.4-1.31.4-1.5
Sr content in liver1.61.41.80.61.31.31.11.1-1.11.11.1-1.11.31.3-1.21.2-1.31.2
Zn content in liver0.10.10.40.1-0.6-0.2-0.1-0.10.1-0.1-0.10.1-0.4-0.20.5-0.60.5-0.4
Bone: minimum diameter0.10.20.5-0.70.50.20.20.2-0.20.20.2-0.20.50.2-0.40.6-0.40.3
Time in familiar zone, hab. session 10.10.10.9-0.90.4-0.1-0.1-0.10.1-0.1-0.10.10.3-0.1-0.20.3-0.20.1
Time in novel zone, hab. session 10.00.00.6-0.80.10.00.00.0-0.00.00.0-0.00.10.00.00.00.0-0.1
Total zone transitions, hab. session 12.23.04.8-0.22.21.61.61.6-1.61.61.6-1.61.91.5-2.12.1-2.12.0
Total locomotion distance, hab. session 10.91.32.9-1.21.70.80.80.8-0.80.80.8-0.81.40.8-1.51.6-1.41.2
Locomotion velocity, hab. session 10.40.61.6-0.61.30.50.50.5-0.50.50.5-0.51.00.5-1.11.2-1.00.9
Time in familiar zone, hab. session 20.10.10.4-0.30.60.00.00.0-0.00.00.0-0.00.40.0-0.40.6-0.40.3
Time in novel zone, hab. session 20.10.11.0-1.0-0.2-0.2-0.2-0.20.2-0.2-0.20.2-0.1-0.10.4-0.30.3-0.4
Total zone transitions, hab. session 21.62.13.60.01.91.31.31.3-1.31.31.3-1.31.61.2-1.71.9-1.71.6
Total locomotion distance, hab. session 21.11.52.9-0.81.71.01.01.0-1.01.01.0-1.01.51.0-1.41.5-1.41.3
Locomotion velocity, hab. session 21.21.62.5-0.31.61.21.21.2-1.21.21.2-1.21.51.2-1.51.4-1.41.4
Novel to familiar place preference ratio0.20.20.3-0.5-0.5-0.4-0.4-0.40.4-0.4-0.40.4-0.5-0.40.5-0.60.5-0.5
Novelty place preference0.60.70.8-0.5-0.8-0.8-0.8-0.80.8-0.8-0.80.8-0.9-0.80.9-0.90.9-0.8
Time in novel zone, NPP test1.01.11.2-0.8-1.0-1.1-1.1-1.11.1-1.1-1.11.1-1.0-1.11.1-1.01.1-1.1
Total zone transitions, NPP test1.82.54.90.02.11.41.41.4-1.41.41.4-1.41.81.3-2.02.2-1.91.8
Total locomotion distance, NPP test1.41.93.4-0.51.91.21.21.2-1.21.21.2-1.21.61.1-1.71.8-1.61.5
Locomotion velocity, NPP test2.53.65.1-0.12.31.81.81.8-1.81.81.8-1.82.11.8-2.22.2-2.22.1
Intraocular pressure2.84.030.6-5.50.3-1.8-1.8-1.81.8-1.8-1.81.8-0.1-1.80.7-0.20.8-1.2
Delta distance traveled before/after self-admin1.01.12.3-1.41.50.70.80.8-0.80.80.8-0.81.40.7-1.11.4-1.10.9
Delta ambulatory time before/after self-admin1.61.93.2-0.81.81.21.31.3-1.31.31.3-1.31.71.2-1.51.7-1.51.4
Parametrial fat weight2.76.48.3-0.3-2.2-2.7-2.9-2.92.9-2.9-2.92.9-2.5-2.72.3-2.12.3-2.3
Pavlov. Cond. lever latency0.10.20.8-0.9-0.2-0.4-0.4-0.40.4-0.4-0.40.4-0.2-0.40.3-0.40.3-0.4
Pavlov. Cond. magazine entry latency0.20.20.40.60.30.60.60.6-0.60.60.6-0.60.50.6-0.30.3-0.40.4
Pavlov. Cond. change in total contacts0.00.00.1-0.30.10.10.10.1-0.10.10.1-0.10.20.1-0.00.1-0.10.0
Pavlov. Cond. index score0.10.10.70.8-0.00.40.40.4-0.40.40.4-0.40.10.4-0.10.2-0.20.3
Pavlov. Cond. latency score0.10.10.30.50.10.40.40.4-0.40.40.4-0.40.20.4-0.20.2-0.20.2
Pavlov. Cond. lever contacts0.10.10.20.20.30.40.40.4-0.40.40.4-0.40.40.4-0.30.4-0.40.4
Pavlov. Cond. magazine entry number0.70.91.0-0.7-0.8-1.0-1.0-1.01.0-1.0-1.01.0-0.9-1.00.9-1.00.9-0.9
Pavlov. Cond. intertrial magazine entries0.30.41.2-1.1-0.1-0.7-0.7-0.70.7-0.7-0.70.7-0.3-0.70.3-0.10.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.51.20.10.60.60.6-0.60.60.6-0.60.20.6-0.30.3-0.30.4
Pavlov. Cond. response bias0.40.50.90.90.50.70.70.7-0.70.70.7-0.70.60.8-0.60.7-0.60.7
Pavlov. Cond. lever latency1.01.41.6-0.3-1.2-1.3-1.3-1.31.3-1.3-1.31.3-1.2-1.31.3-1.01.2-1.2
Pavlov. Cond. magazine entry latency1.31.62.1-0.21.31.41.41.4-1.41.41.4-1.41.41.4-1.31.1-1.31.2
Pavlov. Cond. change in total contacts1.22.02.60.21.61.41.41.4-1.41.41.4-1.41.61.4-1.51.3-1.51.4
Pavlov. Cond. index score1.92.53.10.11.61.71.71.7-1.71.71.7-1.71.71.7-1.61.5-1.61.6
Pavlov. Cond. latency score1.41.92.30.11.41.51.51.5-1.51.51.5-1.51.51.5-1.41.2-1.41.4
Pavlov. Cond. lever contacts1.21.61.80.21.31.31.31.3-1.31.31.3-1.31.31.3-1.31.1-1.31.3
Pavlov. Cond. magazine entry number2.43.03.80.1-1.8-1.8-1.8-1.81.8-1.8-1.81.8-1.9-1.81.8-1.61.8-1.7
Pavlov. Cond. intertrial magazine entries1.92.83.5-0.6-1.5-1.9-1.9-1.91.9-1.9-1.91.9-1.7-1.91.5-1.31.6-1.6
Pavlov. Cond. lever-magazine prob. diff.2.12.83.40.11.71.81.81.8-1.81.81.8-1.81.81.8-1.71.5-1.71.7
Pavlov. Cond. response bias1.82.53.1-0.11.71.61.61.6-1.61.61.6-1.61.71.6-1.71.5-1.71.6
Time in closed arm before self-admin1.31.72.11.11.11.31.41.4-1.41.41.4-1.41.21.3-1.21.2-1.21.2
Time in closed arm after self-admin0.50.51.8-1.30.1-0.8-0.8-0.80.8-0.8-0.80.8-0.1-0.80.40.00.4-0.6
Time in open arm before self-admin0.10.11.01.0-0.3-0.1-0.1-0.10.1-0.1-0.10.1-0.3-0.10.1-0.30.1-0.1
Time in open arm after self-admin1.61.710.03.2-0.01.31.31.3-1.31.31.3-1.30.21.3-0.80.2-0.81.1
Bone: periosteal estimation0.20.31.1-1.10.90.30.30.3-0.30.30.3-0.30.80.3-0.60.9-0.60.5
Bone: periosteal perimeter0.10.10.5-0.70.1-0.4-0.4-0.40.4-0.4-0.40.4-0.2-0.50.00.10.1-0.1
Bone: post-yield work0.60.97.5-2.71.5-0.1-0.1-0.10.1-0.1-0.10.11.1-0.1-0.81.4-0.70.4
Progressive ratio test 1 active lever presses1.61.92.5-1.2-1.0-1.6-1.6-1.61.6-1.6-1.61.6-1.2-1.61.2-0.91.3-1.3
Progressive ratio test 1 breakpoint1.72.12.7-1.2-1.0-1.6-1.6-1.61.6-1.6-1.61.6-1.2-1.61.3-0.91.3-1.4
Progressive ratio test 1 inactive lever presses0.50.71.50.61.10.70.70.7-0.70.70.7-0.70.90.7-1.01.2-1.00.9
Progressive ratio test 2 active lever presses2.73.213.2-3.6-0.3-1.9-1.9-1.91.9-1.9-1.91.9-0.7-1.91.1-0.51.1-1.4
Progressive ratio test 2 breakpoint2.62.912.8-3.6-0.2-1.8-1.8-1.81.8-1.8-1.81.8-0.6-1.81.0-0.41.0-1.4
Progressive ratio test 2 inactive lever presses0.71.110.1-3.21.5-0.3-0.3-0.30.3-0.3-0.30.31.0-0.3-0.61.2-0.60.2
Incentive Sensitization - Responses1.31.813.0-3.60.6-1.3-1.3-1.31.3-1.3-1.31.30.1-1.30.30.40.4-0.8
Incentive Sensitization - Breakpoint1.21.612.9-3.60.7-1.1-1.1-1.11.1-1.1-1.11.10.2-1.10.20.50.2-0.6
Sum of active levers in priming session hrs 5-610.59.810.90.83.23.23.23.2-3.23.23.2-3.23.23.2-3.33.1-3.33.3
Progressive ratio0.40.63.92.0-1.2-0.1-0.1-0.10.1-0.1-0.10.1-1.0-0.30.7-1.10.7-0.5
Food seeking constrained by brief footshock0.60.75.7-2.40.1-0.7-0.7-0.70.7-0.7-0.70.7-0.0-0.70.4-0.10.4-0.6
Seeking ratio, punishment vs. effort0.50.77.5-2.71.0-0.2-0.2-0.20.2-0.2-0.20.20.8-0.1-0.40.9-0.40.1
Retroperitoneal fat weight1.46.019.74.4-2.9-2.0-2.1-2.12.1-2.1-2.12.1-3.0-1.72.2-2.42.2-1.9
Reaction time number correct2.14.19.53.11.62.12.02.0-2.02.02.0-2.01.72.1-1.81.5-1.91.9
Reaction time mean minus median0.20.43.8-1.90.8-0.4-0.3-0.30.3-0.3-0.30.30.5-0.2-0.40.7-0.30.2
Reaction time mean minus median AUC0.71.712.6-3.50.1-1.3-1.2-1.21.2-1.2-1.21.2-0.1-1.10.6-0.20.6-0.9
Reaction time num false alarms0.10.10.7-0.90.00.30.20.2-0.20.20.2-0.20.20.20.0-0.0-0.00.0
Reaction time num false alarms AUC0.10.10.9-0.9-0.5-0.0-0.1-0.10.1-0.1-0.10.1-0.3-0.10.4-0.60.4-0.3
Reaction time trials correct on left2.14.19.53.11.62.12.02.0-2.02.02.0-2.01.72.1-1.81.5-1.91.9
Reaction time trials on left2.24.29.63.11.72.12.02.0-2.02.02.0-2.01.72.1-1.91.6-1.92.0
Reaction time mean0.00.10.4-0.70.50.00.00.0-0.00.00.0-0.00.40.0-0.10.4-0.10.0
Reaction time mean AUC0.10.21.7-1.30.5-0.1-0.1-0.10.1-0.1-0.10.10.4-0.1-0.10.4-0.1-0.0
Median of all reaction times0.00.00.1-0.00.0-0.1-0.1-0.10.1-0.1-0.10.10.1-0.10.2-0.00.2-0.3
Reaction time omissions0.10.10.20.20.40.10.10.1-0.10.10.1-0.10.30.4-0.40.4-0.40.4
Reaction time false alarm rate1.21.74.5-2.1-1.3-1.1-1.2-1.21.2-1.2-1.21.2-1.2-1.21.4-1.31.3-1.3
Reaction time premature initiation rate0.10.20.3-0.40.30.50.50.5-0.50.50.5-0.50.40.3-0.20.3-0.30.2
Reaction time premature initiations1.42.43.11.81.21.71.71.7-1.71.71.7-1.71.31.6-1.31.2-1.41.4
Std. dev. reaction times0.20.44.3-2.10.9-0.2-0.2-0.20.2-0.2-0.20.20.7-0.1-0.30.8-0.30.1
Reaction time trials completed2.24.29.63.11.72.12.02.0-2.02.02.0-2.01.72.1-1.91.6-1.92.0
Reaction time trials AUC2.14.19.43.11.62.12.02.0-2.02.02.0-2.01.72.1-1.81.5-1.91.9
Run reversals in cocaine runway, females0.10.10.20.2-0.4-0.4-0.4-0.40.4-0.4-0.40.4-0.4-0.40.4-0.50.4-0.4
Run reversals in cocaine runway, males0.50.51.4-1.2-0.3-0.8-0.8-0.80.8-0.8-0.80.8-0.4-0.70.5-0.30.5-0.6
Latency to leave start box in cocaine runway2.02.23.50.9-1.9-1.4-1.4-1.41.4-1.4-1.41.4-1.8-1.41.6-1.71.6-1.5
Latency to leave start box in cocaine runway, F2.83.15.11.1-2.3-1.6-1.6-1.61.6-1.6-1.61.6-2.2-1.62.0-2.01.9-1.8
Latency to leave start box in cocaine runway, M0.00.00.10.40.00.10.10.1-0.10.10.1-0.10.00.1-0.10.0-0.10.1
Std. dev. time between licks in bursts1.11.42.21.00.41.51.51.5-1.51.51.5-1.50.91.4-0.70.5-0.80.9
Total sessions with >9 infusions0.40.53.2-1.80.1-0.7-0.7-0.70.7-0.7-0.70.7-0.1-0.70.30.10.3-0.5
Short access day 1 total inactive lever presses1.11.55.1-2.21.90.60.60.6-0.60.60.6-0.61.60.7-1.31.7-1.31.1
Short access day 10 total inactive lever presses1.22.84.2-0.42.01.61.61.6-1.61.61.6-1.62.01.6-1.91.8-1.81.7
Short access day 1 total infusions0.70.98.9-3.00.6-0.7-0.7-0.70.7-0.7-0.70.70.3-0.7-0.00.50.0-0.3
Short access day 10 total infusions0.30.43.7-1.90.2-0.5-0.5-0.50.5-0.5-0.50.50.1-0.60.20.20.2-0.3
Short access total infusions0.60.73.8-2.0-0.0-0.9-0.9-0.90.9-0.9-0.90.9-0.2-0.90.4-0.10.5-0.6
Short access day 1 locomotion0.30.41.5-1.21.00.30.30.3-0.30.30.3-0.30.80.3-0.71.0-0.70.6
Short access day 10 total locomotion0.10.10.7-0.90.60.10.10.1-0.10.10.1-0.10.50.1-0.30.6-0.30.2
Short access total locomotion0.50.72.9-1.7-0.2-0.9-0.9-0.90.9-0.9-0.90.9-0.3-0.80.5-0.20.5-0.6
One hour access (0.3 mA shock)0.10.10.4-0.70.4-0.0-0.0-0.00.0-0.0-0.00.00.3-0.0-0.20.4-0.20.1
Compulsive drug intake0.10.10.60.8-0.10.20.20.2-0.20.20.2-0.2-0.00.3-0.1-0.1-0.10.2
One hour access (shock baseline)0.20.22.2-1.50.6-0.3-0.3-0.30.3-0.3-0.30.30.3-0.3-0.20.5-0.20.0
Social response proportion1.31.51.90.9-1.3-1.2-1.3-1.31.3-1.3-1.31.3-1.4-1.21.2-1.01.2-1.1
Social responses0.81.01.5-1.1-0.5-1.1-1.2-1.21.2-1.2-1.21.2-0.6-1.00.7-0.50.8-0.9
Social time0.10.10.2-0.4-0.2-0.4-0.4-0.40.4-0.4-0.40.4-0.3-0.30.1-0.00.1-0.1
Soleus weight0.30.91.60.31.20.80.80.8-0.80.80.8-0.81.01.0-1.31.1-1.21.2
Bone: stiffness0.00.00.10.40.00.20.20.2-0.20.20.2-0.20.10.2-0.10.3-0.20.2
Tibialis anterior weight0.10.32.61.60.10.30.20.2-0.20.20.2-0.2-0.00.4-0.50.2-0.40.6
Time to tail flick, vehicle, before self-admin0.00.00.00.00.10.0-0.0-0.00.0-0.0-0.00.00.10.0-0.20.2-0.10.1
Time to tail flick, vehicle, after self-admin0.10.11.01.0-0.10.10.10.1-0.10.10.1-0.1-0.10.2-0.0-0.0-0.10.1
Time to tail flick, test, before self-admin1.51.62.7-1.6-0.8-1.5-1.3-1.31.3-1.3-1.31.3-0.9-1.41.1-0.91.1-1.2
Time to tail flick, test, after self-admin2.42.54.12.0-2.0-1.3-1.4-1.41.4-1.4-1.41.4-1.9-1.31.6-1.91.6-1.4
Delta time to tail flick, vehicle, before/after SA0.00.00.10.3-0.1-0.0-0.1-0.10.1-0.1-0.10.1-0.10.00.1-0.10.0-0.0
Delta time to tail flick, test, before/after SA0.30.43.31.8-0.10.60.40.4-0.40.40.4-0.40.00.6-0.30.0-0.30.4
Tibia length0.20.63.82.0-0.10.70.80.8-0.80.80.8-0.80.10.6-0.40.2-0.40.6
Ambulatory time before self-admin0.10.11.51.2-0.30.30.30.3-0.30.30.3-0.3-0.10.3-0.0-0.2-0.00.2
Ambulatory time after self-admin3.44.04.40.82.02.02.02.0-2.02.02.0-2.02.12.0-2.12.0-2.12.0
Bone: tissue strength0.20.21.11.0-0.4-0.3-0.3-0.30.3-0.3-0.30.3-0.5-0.30.2-0.10.2-0.1
Total heroin consumption0.50.65.22.3-0.20.50.80.8-0.80.80.8-0.8-0.00.6-0.2-0.0-0.20.4
Bone: trabecular number2.84.67.12.71.32.32.32.3-2.32.32.3-2.31.62.3-1.81.5-1.92.1
Bone: trabecular spacing4.45.86.4-1.4-2.3-2.5-2.5-2.52.5-2.5-2.52.5-2.4-2.52.5-2.22.5-2.5
Bone: trabecular thickness1.72.12.30.81.41.51.51.5-1.51.51.5-1.51.51.5-1.51.4-1.51.5
Bone: trabecular tissue density1.42.12.8-0.3-1.1-1.6-1.6-1.61.6-1.6-1.61.6-1.4-1.71.3-0.91.3-1.4
Water consumed over 24 hours0.60.92.3-1.21.50.40.50.5-0.50.50.5-0.51.20.6-1.21.5-1.21.0
Number of responses in last shaping day0.60.64.1-2.01.30.10.10.1-0.10.10.1-0.11.00.1-0.81.2-0.70.5