Tepsin

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Tepsin 0.3 0.25 8.8e-03 0.08 0.05 0.05 0.06 6.6e-03 2.4e-02 2.2e-02 1.8e-02
2 NAcc alternative TSS XM_006247895.4 0.07 0.04 3.8e-07 0.05 0.06 0.05 0.06 3.3e-06 3.6e-07 9.5e-07 1.1e-07
3 PL alternative TSS NM_001100729.1 0.04 0.03 1.2e-03 0.03 0.03 0.03 0.03 3.3e-04 3.1e-04 4.0e-04 6.1e-04
4 NAcc alternative TSS NM_001100729.1 0.06 0.05 1.4e-05 0.04 0.04 0.04 0.04 6.3e-05 3.6e-05 4.4e-05 8.3e-06
5 PL alternative TSS XM_006247895.4 0.05 0.04 3.9e-05 0.05 0.04 0.04 0.04 5.4e-06 8.9e-06 3.5e-05 1.4e-05
6 Brain alternative TSS NM_001100729.1 0.06 0.04 7.4e-05 0.05 0.05 0.03 0.04 3.4e-05 4.3e-05 1.7e-03 8.2e-05
7 Brain alternative TSS XM_006247895.4 0.06 0.05 2.1e-04 0.04 0.04 0.03 0.04 4.5e-05 6.5e-05 5.8e-04 5.5e-05
8 Adipose intron excision ratio chr10_105377639_105378492 0.03 0.02 3.8e-03 0.02 0.02 0.02 0.02 1.1e-03 4.2e-03 4.7e-03 1.6e-03
9 RMTg mRNA stability Tepsin 0.18 0.11 5.1e-03 0.07 0.07 0.02 0.09 6.9e-03 7.3e-03 1.0e-01 2.1e-03
10 NAcc intron excision ratio chr10_105377639_105378492 0.03 0.02 3.0e-03 0.01 0.01 0 0 2.9e-02 4.8e-02 2.3e-01 7.7e-02
11 BLA gene expression Tepsin 0.14 0.08 1.3e-04 0.05 0.05 0.04 0.03 7.6e-04 1.1e-03 2.8e-03 6.1e-03
12 Liver gene expression Tepsin 0.04 0.03 1.1e-03 0.02 0.02 0.02 0.02 1.1e-03 2.4e-03 3.7e-03 6.6e-03
13 Adipose alternative TSS XM_039086442.1 0.03 0.02 6.2e-03 0.02 0.02 0.02 0.02 2.6e-03 6.2e-03 5.4e-03 6.5e-03
14 NAcc gene expression Tepsin 0.08 0.04 2.4e-08 0.08 0.07 0.08 0.07 3.3e-09 1.5e-08 4.1e-09 4.4e-09
15 BLA mRNA stability Tepsin 0.1 0.07 1.3e-03 0.04 0.03 0 0.04 4.0e-03 8.0e-03 1.9e-01 4.6e-03
16 Brain intron excision ratio chr10_105377639_105378492 0.03 0.03 6.5e-03 0.02 0.01 0.01 0.01 3.0e-03 1.6e-02 7.2e-02 1.6e-02
17 pVTA alternative TSS NM_001100729.1 0.12 0.07 4.3e-04 0.12 0.09 0.11 0.12 5.9e-06 1.2e-04 1.8e-05 1.2e-05
18 pVTA alternative TSS XM_006247895.4 0.1 0.06 1.7e-03 0.1 0.07 0.07 0.09 3.2e-05 5.4e-04 4.0e-04 1.1e-04
19 Brain mRNA stability Tepsin 0.35 0.11 0.0e+00 0.26 0.26 0.25 0.26 6.4e-24 2.7e-24 1.5e-23 1.4e-24
20 Adipose mRNA stability Tepsin 0.14 0.1 1.2e-10 0.08 0.09 0.08 0.09 1.4e-09 2.1e-10 1.5e-09 5.2e-10
21 NAcc mRNA stability Tepsin 0.07 0.05 8.5e-05 0.02 0.03 0.03 0.03 8.1e-04 1.4e-04 9.6e-05 2.8e-04
22 Liver mRNA stability Tepsin 0.06 0.04 3.9e-05 0.02 0.04 0.04 0.04 3.8e-03 2.6e-05 6.4e-05 6.0e-05
23 LHb mRNA stability Tepsin 0.53 0.27 7.2e-04 0.05 0.06 0.03 0.04 2.5e-02 1.9e-02 7.5e-02 4.2e-02
24 PL mRNA stability Tepsin 0.17 0.09 6.1e-11 0.09 0.1 0.12 0.09 1.8e-10 8.7e-11 4.1e-13 1.9e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.20.31.2-0.3-0.80.60.80.7-0.80.8-0.10.1-0.4-0.2-0.3-0.0-0.9-0.3-0.2-1.11.10.30.3-0.40.50.4-0.2
Area under the delay curve0.80.81.9-0.81.3-1.3-1.2-1.00.7-0.7-1.41.1-1.1-0.6-0.6-1.10.9-1.3-0.70.8-0.81.00.5-0.40.10.2-0.7
BMI with tail0.72.45.6-1.0-1.82.21.92.2-2.32.3-0.90.6-0.4-0.8-0.70.2-2.4-0.9-0.4-2.12.11.30.9-1.41.41.8-1.0
BMI without tail4.69.522.0-1.0-4.34.74.44.5-4.74.7-1.50.80.2-0.9-0.90.4-4.7-1.4-0.6-4.34.32.11.9-2.83.03.3-1.7
Body weight1.87.419.92.2-4.54.04.23.1-3.23.22.4-2.62.52.32.32.5-3.32.32.7-3.53.5-1.6-1.10.50.00.01.3
Weight adjusted by age1.41.64.40.6-1.82.11.71.2-1.41.41.1-1.21.51.51.51.5-1.91.01.1-1.11.1-0.7-0.7-0.2-0.20.20.4
Bone surface0.30.41.10.8-0.60.00.6-0.10.1-0.11.0-0.90.60.80.80.50.00.90.7-0.50.5-0.9-0.70.8-0.5-0.80.8
Bone volume0.10.20.70.2-0.80.50.80.4-0.40.40.4-0.40.30.30.30.3-0.50.30.2-0.80.8-0.2-0.20.20.0-0.10.3
Breakpoint value in progressive ratio session0.40.42.4-0.4-0.01.2-0.10.6-0.70.7-0.3-0.41.4-0.2-0.21.6-0.2-0.20.50.5-0.50.4-0.5-0.2-0.21.00.3
Number of licking bursts0.20.20.70.3-0.80.20.80.5-0.10.10.4-0.2-0.00.20.2-0.3-0.30.50.3-0.80.8-0.40.20.20.3-0.30.2
Context. condit. distance diff. score2.42.95.1-1.5-1.71.71.92.1-2.22.2-1.21.2-0.5-1.3-1.4-1.0-2.3-1.3-0.9-2.12.11.61.8-1.92.11.9-1.3
Locomotion velocity, session 12.12.26.90.52.4-2.3-2.4-2.62.4-2.40.1-0.20.20.30.3-0.12.10.1-0.02.0-2.0-0.6-0.90.9-1.4-1.30.4
Locomotion distance, session 11.51.94.7-1.71.2-1.1-1.0-0.60.4-0.4-1.91.8-1.9-1.7-1.7-2.20.0-1.8-2.00.0-0.01.61.7-1.31.30.9-1.3
Locomotion velocity, session 22.12.47.9-0.82.6-2.8-2.5-2.42.4-2.4-0.60.6-0.4-0.7-0.7-1.52.2-0.4-0.42.0-2.0-0.10.20.7-0.6-1.00.3
Locomotion distance, session 20.60.81.9-1.20.1-0.20.00.2-0.20.2-1.10.9-1.1-1.2-1.2-1.4-0.7-1.0-1.0-0.60.61.01.3-1.11.10.8-0.8
Locomotion velocity, session 30.91.03.3-0.21.8-1.6-1.8-1.71.5-1.5-0.40.5-0.4-0.1-0.1-0.31.3-0.3-0.31.3-1.30.0-0.20.5-0.7-0.60.3
Locomotion distance, session 31.31.43.6-1.51.9-1.6-1.8-1.31.3-1.3-1.31.2-1.0-1.2-1.2-1.21.2-1.2-1.11.1-1.10.90.7-0.30.20.3-0.4
Stereotopy head waving bouts, day 30.70.82.80.11.1-1.1-1.2-1.11.3-1.30.2-0.10.10.20.2-0.01.40.30.21.7-1.7-0.5-0.40.8-0.7-0.80.7
Stereotopy head waving duration, day 30.30.31.2-0.30.7-0.7-0.7-0.60.8-0.80.10.00.1-0.1-0.0-0.20.90.10.11.1-1.1-0.2-0.10.5-0.3-0.40.6
Locomotion velocity, session 70.40.41.0-0.90.7-0.5-0.6-0.20.2-0.2-0.90.8-0.4-1.0-1.0-0.70.1-0.8-0.70.2-0.20.80.7-0.60.50.5-0.7
Locomotion distance, session 73.13.98.7-2.90.9-0.6-0.70.4-0.30.3-2.62.6-2.5-2.8-2.8-2.3-0.6-2.6-2.4-0.50.52.52.4-2.02.12.0-2.0
Stereotopy head waving bouts, day 70.10.10.7-0.1-0.50.70.50.6-0.50.5-0.1-0.10.80.00.10.0-0.3-0.00.30.0-0.00.20.1-0.30.30.40.1
Stereotopy head waving duration, day 70.50.62.80.8-0.70.40.60.20.0-0.00.9-1.01.70.91.00.40.21.01.20.2-0.2-0.9-0.60.7-0.4-0.61.0
Locomotion velocity, session 81.01.22.7-1.3-0.00.10.20.7-0.70.7-1.41.3-0.8-1.5-1.5-1.5-0.6-1.3-1.1-0.60.61.41.6-1.31.51.2-1.2
Locomotion distance, session 84.05.89.8-2.5-1.71.72.02.5-2.62.6-2.22.0-1.7-2.3-2.3-2.1-3.0-2.2-1.8-2.82.82.62.9-2.93.12.7-2.1
Degree of sensitization distance1.21.22.8-0.7-1.21.31.31.7-1.51.5-0.40.5-0.7-0.8-0.8-0.2-1.6-0.5-0.3-1.51.50.80.9-1.01.21.1-1.0
Degree of sensitization stereotypy0.40.41.3-0.1-0.91.10.91.0-1.01.0-0.2-0.11.0-0.00.00.1-0.8-0.10.3-0.50.50.30.3-0.50.50.7-0.1
Conditioned locomotion2.22.67.60.2-2.82.62.82.5-2.52.50.5-0.4-0.00.30.30.7-2.30.40.5-2.52.50.10.3-0.71.00.9-0.2
Cocaine response after cond. corrected0.20.20.5-0.40.70.0-0.7-0.2-0.10.1-0.60.4-0.5-0.3-0.30.50.3-0.7-0.50.6-0.60.6-0.2-0.2-0.20.5-0.3
Cocaine response after cond. not corrected0.40.41.3-0.41.1-0.6-1.1-0.80.5-0.5-0.70.5-0.6-0.3-0.30.00.9-0.8-0.50.9-0.90.6-0.1-0.0-0.30.2-0.2
Cocaine response before conditioning0.30.31.4-0.30.6-1.2-0.5-0.80.9-0.9-0.20.2-0.1-0.3-0.3-1.20.8-0.3-0.20.3-0.30.10.50.20.2-0.50.2
Saline control response1.31.74.51.4-2.11.72.01.2-1.51.51.3-1.31.31.51.51.3-1.51.01.4-1.31.3-0.7-0.80.4-0.2-0.30.7
Bone: connectivity density0.20.20.8-0.7-0.5-0.10.60.4-0.20.2-0.00.1-0.4-0.6-0.6-0.9-0.4-0.3-0.2-0.80.80.30.6-0.20.70.1-0.0
Bone: cortical apparent density1.11.44.2-1.32.0-1.6-2.0-1.31.1-1.1-1.21.3-1.4-1.1-1.1-1.01.0-1.1-1.51.2-1.20.80.5-0.50.00.3-0.6
Bone: cortical area2.84.37.72.8-2.82.52.51.4-1.51.52.4-2.62.62.52.62.8-1.32.32.3-1.41.4-1.9-1.91.2-1.1-0.81.4
Bone: cortical porosity2.52.86.21.90.5-0.1-0.8-1.10.9-0.91.7-2.11.81.91.92.51.01.71.71.6-1.6-1.8-2.41.9-2.3-1.41.6
Bone: cortical porosity1.71.95.21.60.10.3-0.4-0.50.4-0.41.5-1.81.71.61.62.30.61.51.61.3-1.3-1.4-2.11.5-1.9-1.01.3
Bone: cortical thickness2.74.410.22.9-2.12.11.81.0-0.80.82.8-2.92.72.72.73.2-0.82.72.5-0.60.6-2.3-2.41.5-1.7-1.21.5
Bone: cortical thickness0.60.72.41.1-1.11.40.90.8-0.60.60.8-0.80.81.11.01.6-0.81.00.8-0.30.3-0.7-0.90.4-0.50.00.3
Bone: cortical tissue density1.21.64.8-1.32.2-1.7-2.1-1.41.3-1.3-1.31.4-1.5-1.2-1.2-1.01.1-1.2-1.51.2-1.20.90.5-0.50.00.3-0.7
Condit. Reinf. active minus inactive responses1.01.13.20.8-1.71.81.71.4-1.61.60.5-0.81.20.60.50.8-1.50.50.6-1.21.2-0.1-0.2-0.50.30.5-0.3
Condit. Reinf. active-inactive response ratio0.60.62.1-0.0-1.11.51.11.3-1.31.30.0-0.30.5-0.0-0.00.5-1.10.10.1-1.01.00.20.0-0.60.40.8-0.4
Condit. Reinf. active responses1.72.06.11.3-2.52.32.41.8-2.02.00.9-1.21.51.11.01.0-1.90.91.1-1.61.6-0.5-0.3-0.30.30.4-0.0
Condit. Reinf. inactive responses0.40.51.50.9-1.21.11.20.8-1.01.00.4-0.60.90.60.70.5-0.90.40.8-0.60.6-0.3-0.10.00.10.10.1
Incentive salience index mean0.91.03.01.0-1.71.51.71.2-1.41.40.6-0.91.30.70.70.5-1.30.70.8-1.11.1-0.3-0.1-0.30.30.2-0.0
Condit. Reinf. lever presses0.10.20.6-0.0-0.60.30.70.5-0.50.5-0.10.00.4-0.1-0.2-0.8-0.4-0.0-0.0-0.70.70.20.6-0.40.60.2-0.2
Condit. Reinf. active minus inactive responses0.40.51.20.5-1.10.91.10.9-0.80.80.7-1.00.60.50.50.3-0.90.70.8-0.70.7-0.5-0.10.20.1-0.10.5
Condit. Reinf. active-inactive response ratio1.31.43.31.4-1.20.91.00.5-0.30.31.6-1.81.31.51.51.3-0.51.61.8-0.30.3-1.4-1.11.2-0.8-0.81.3
Condit. Reinf. active responses0.40.51.4-0.7-0.71.00.81.2-1.21.2-0.40.1-0.3-0.6-0.6-0.2-1.1-0.4-0.3-0.70.70.60.7-0.80.80.9-0.4
Condit. Reinf. inactive responses1.11.42.7-1.60.40.1-0.30.6-0.70.7-1.61.4-1.2-1.6-1.6-1.0-0.4-1.5-1.6-0.20.21.61.3-1.61.21.5-1.3
Condit. Reinf. lever presses1.52.03.8-1.5-0.81.50.91.9-1.81.8-1.21.1-1.1-1.4-1.4-0.4-1.8-1.4-1.2-1.21.21.61.2-1.71.52.0-1.4
Condit. Reinf. lever reinforcers received1.11.63.1-1.4-0.81.40.91.7-1.71.7-1.00.7-0.8-1.2-1.2-0.4-1.7-1.0-0.9-1.01.01.31.1-1.51.41.8-1.0
Conditioned reinforcement - actives0.30.31.2-1.1-1.00.41.00.8-0.70.70.4-0.2-0.40.20.2-0.7-0.50.40.4-0.50.5-0.20.50.10.5-0.10.8
Conditioned reinforcement - inactives0.91.02.11.0-1.21.21.11.0-1.01.01.1-1.31.21.11.11.5-1.21.11.4-0.60.6-0.9-0.70.4-0.4-0.10.6
Conditioned locomotion0.40.51.50.3-0.80.40.70.5-0.30.31.2-0.90.40.90.9-0.2-0.41.20.8-0.50.5-1.0-0.20.6-0.1-0.61.1
Patch foraging indifference point 0 sec0.10.20.6-0.4-0.30.80.30.8-0.70.7-0.20.20.1-0.4-0.30.5-0.4-0.4-0.2-0.50.50.50.1-0.60.30.7-0.3
Patch foraging indifference point AUC0.10.10.3-0.10.00.00.00.1-0.30.3-0.30.4-0.5-0.2-0.2-0.3-0.3-0.3-0.5-0.10.10.30.3-0.40.30.2-0.5
Delay disc. indifference point, 0s delay0.00.10.5-0.4-0.2-0.00.1-0.0-0.20.20.0-0.0-0.20.20.2-0.3-0.30.10.10.1-0.10.10.1-0.70.0-0.1-0.3
Delay disc. indifference point, 16s delay2.32.34.8-2.00.6-0.4-0.40.0-0.40.4-2.22.0-2.1-1.8-1.8-2.1-0.5-2.2-1.8-0.80.82.11.8-1.71.61.4-1.6
Delay disc. indifference point, 2s delay0.20.20.7-0.30.7-0.6-0.7-0.80.5-0.5-0.2-0.00.30.10.1-0.30.6-0.20.10.8-0.80.2-0.1-0.2-0.3-0.2-0.0
Delay disc. indifference point, 24s delay2.22.16.3-0.42.5-2.3-2.5-2.01.7-1.7-1.41.0-1.0-0.4-0.4-1.12.3-1.2-0.62.0-2.00.70.10.6-0.5-0.4-0.2
Delay disc. indifference point, 4s delay0.30.31.0-1.00.9-0.9-0.8-0.80.6-0.6-0.40.0-0.0-0.4-0.4-0.30.8-0.5-0.11.0-1.00.2-0.10.0-0.3-0.20.3
Delay disc. indifference point, 8s delay0.70.71.90.21.3-1.4-1.3-1.41.1-1.1-0.50.2-0.20.50.5-0.21.4-0.40.11.3-1.30.1-0.40.5-0.7-0.60.1
Indifference point function ln k0.40.61.8-1.30.8-0.6-0.7-0.10.3-0.3-1.01.0-0.7-1.2-1.2-0.80.3-1.2-0.90.3-0.30.90.7-0.60.60.7-0.5
Indifference point function log k0.40.61.8-1.30.8-0.6-0.7-0.10.3-0.3-1.01.0-0.7-1.2-1.2-0.80.3-1.2-0.90.3-0.30.90.7-0.60.60.7-0.5
Patch foraging total patch changes 0 sec0.40.61.5-0.9-0.41.00.41.1-1.11.1-0.60.5-0.1-0.8-0.70.3-0.7-0.8-0.5-0.70.70.90.4-1.00.61.2-0.6
Patch foraging total patch changes 12 sec0.00.00.3-0.00.20.2-0.30.0-0.10.1-0.0-0.00.1-0.10.00.50.20.0-0.10.1-0.10.1-0.2-0.1-0.20.2-0.0
Patch foraging total patch changes 18 sec1.62.14.0-1.9-0.20.80.31.0-1.11.1-1.61.7-1.5-1.7-1.6-0.8-1.1-1.7-1.8-1.31.31.91.4-2.01.51.8-1.5
Patch foraging total patch changes 24 sec0.60.72.30.2-1.01.51.01.3-1.31.3-0.10.0-0.00.10.10.5-1.3-0.1-0.1-1.31.30.40.2-0.80.50.8-0.5
Patch foraging total patch changes 6 sec0.30.41.11.0-0.40.40.30.2-0.20.20.9-0.80.90.91.01.0-0.00.80.80.2-0.2-0.7-0.80.5-0.7-0.50.6
Patch foraging time to switch 0 sec0.30.41.4-0.00.9-1.1-0.9-1.21.1-1.1-0.30.2-0.40.00.0-0.41.0-0.1-0.20.7-0.7-0.1-0.10.6-0.4-0.50.3
Patch foraging water rate 0 sec1.72.78.6-0.3-2.42.92.32.9-2.72.7-0.1-0.10.6-0.3-0.20.7-2.3-0.10.2-1.91.90.70.6-1.31.21.7-0.6
Patch foraging water rate 12 sec1.62.44.4-2.0-1.11.61.22.1-2.02.0-1.41.1-0.7-1.8-1.7-0.7-1.6-1.3-0.9-1.51.51.61.5-1.71.82.1-1.0
Patch foraging water rate 18 sec1.31.75.0-0.9-1.61.91.72.2-1.71.7-0.50.40.1-0.9-0.9-0.5-1.6-0.3-0.2-1.91.90.71.2-1.31.61.5-0.6
Patch foraging water rate 24 sec4.46.114.5-2.1-2.53.42.73.8-3.43.4-1.61.2-0.8-1.8-1.8-0.3-3.2-1.6-1.2-2.92.92.22.0-2.72.73.2-1.6
Patch foraging water rate 6 sec0.50.72.2-1.0-0.81.00.91.5-1.01.0-0.30.00.4-1.0-1.0-0.6-0.7-0.4-0.2-1.21.20.60.9-0.81.01.0-0.3
Seeking ratio, delayed vs. immediate footshock0.70.81.8-0.2-1.40.91.30.4-0.80.80.7-0.81.11.31.30.8-1.30.61.3-0.80.8-0.4-0.5-0.0-0.2-0.40.7
Distance traveled before self-admin0.80.85.20.4-0.61.10.50.5-0.80.80.5-1.12.30.80.81.9-0.30.51.5-0.10.1-0.4-1.00.5-0.70.20.6
Distance traveled after self-admin1.21.32.5-1.1-1.01.51.01.6-1.51.5-0.90.60.4-1.0-1.00.4-1.4-0.9-0.3-1.41.41.20.8-1.31.11.6-0.8
Extensor digitorum longus weight1.04.06.0-2.2-1.41.71.62.3-2.42.4-1.71.7-1.7-1.9-1.9-1.3-2.2-2.0-1.4-2.32.32.22.1-2.12.42.4-1.6
Bone: elastic displacement0.50.62.30.8-0.81.10.70.8-0.60.61.0-1.00.60.80.81.5-0.20.90.8-0.30.3-0.7-1.00.5-0.6-0.10.5
Bone: elastic work3.54.514.92.9-1.72.11.30.8-0.80.82.6-2.82.52.72.73.9-0.52.62.6-0.10.1-2.2-2.81.6-2.1-1.01.6
Bone: endosteal estimation0.51.01.9-1.0-0.70.70.80.9-1.11.1-1.11.1-0.9-0.8-0.8-0.9-1.0-1.1-0.8-1.41.41.21.2-1.01.31.1-0.7
Bone: endosteal perimeter0.40.82.41.5-1.20.71.10.1-0.40.41.0-1.01.11.41.30.9-0.50.81.1-0.80.8-0.8-0.80.8-0.5-0.70.7
Epididymis fat weight0.81.94.90.2-2.22.12.22.1-2.12.10.2-0.30.30.10.10.4-2.10.10.2-2.22.20.30.4-0.91.00.9-0.4
Delta time in closed arm before/after self-admin1.01.03.21.2-0.1-0.60.1-0.40.9-0.91.8-1.1-0.20.90.9-0.80.41.71.0-0.30.3-1.7-0.31.4-0.4-1.51.2
Delta time in open arm before/after self-admin1.31.22.7-1.4-0.51.00.61.0-1.51.5-1.61.2-0.5-0.8-0.8-0.2-0.9-1.5-1.0-0.50.51.70.9-1.61.11.5-1.0
Diff in mean of infusions in LGA sessions0.10.10.7-0.50.4-0.2-0.5-0.30.2-0.2-0.1-0.10.8-0.1-0.10.10.4-0.20.10.5-0.50.20.0-0.1-0.10.00.5
Delay discount exponential model param1.11.12.90.8-1.71.61.61.4-1.11.11.4-1.11.00.60.61.0-1.31.30.8-1.21.2-0.9-0.40.20.10.00.5
Extinction: sum of active levers before priming0.60.61.7-0.91.3-0.7-1.3-0.50.8-0.8-0.70.5-0.1-1.2-1.2-0.40.7-0.8-0.51.0-1.00.50.2-0.10.00.5-0.3
Active lever presses in extinction session 60.30.31.0-0.00.80.4-0.90.2-0.30.3-0.4-0.21.0-0.1-0.10.80.3-0.30.41.0-1.00.4-0.30.0-0.40.70.2
Bone: final force2.23.68.22.1-2.92.82.61.8-2.02.01.8-2.02.22.12.12.5-1.91.81.9-1.61.6-1.2-1.40.5-0.5-0.11.0
Bone: final moment2.54.19.02.3-2.93.02.71.9-2.22.21.9-2.22.42.22.22.9-2.01.92.1-1.51.5-1.3-1.60.6-0.7-0.11.1
Food consumed during 24 hour testing period0.30.41.60.7-0.81.30.81.3-0.90.90.1-0.40.5-0.2-0.20.4-0.7-0.10.2-0.40.40.20.2-0.50.40.8-0.5
Glucose2.84.214.00.13.6-2.4-3.7-2.82.6-2.6-0.40.00.1-0.00.00.92.9-0.4-0.03.7-3.7-0.2-1.51.4-2.1-0.80.5
Heart weight0.20.31.00.4-0.80.90.80.5-1.01.0-0.1-0.00.10.30.40.6-0.9-0.0-0.2-0.60.60.3-0.1-0.60.10.4-0.3
Delay discount hyperbolic model param1.01.12.70.9-1.71.61.61.4-1.01.01.3-1.00.90.60.61.0-1.31.30.7-1.31.3-0.9-0.40.30.1-0.00.5
Intermittent access intake day 1-15 change0.20.21.00.1-0.30.60.30.4-0.30.30.5-0.50.30.20.21.0-0.50.40.6-0.10.1-0.3-0.50.1-0.30.1-0.0
Intermittent access intake escalation0.20.20.5-0.0-0.50.70.50.5-0.50.50.3-0.40.20.20.20.7-0.60.30.6-0.20.2-0.2-0.30.1-0.00.20.1
Intermittent access intake escalation 21.21.23.80.4-0.51.00.40.5-0.40.41.3-1.71.91.01.01.6-0.51.32.00.3-0.3-1.1-1.41.0-1.0-0.31.2
Intermitt. access day 1 inactive lever presses0.80.83.61.9-0.91.40.80.9-1.31.30.4-0.61.21.01.01.4-0.90.50.7-0.50.5-0.3-0.60.1-0.30.3-0.1
Intermitt. access day 15 inactive lever presses1.01.13.1-0.0-1.61.71.61.7-1.61.60.4-0.50.7-0.0-0.00.2-1.60.40.8-1.41.4-0.10.3-0.40.70.7-0.2
Intermitt. access escalation Index1.00.92.71.1-1.61.11.61.2-1.41.40.3-0.1-0.20.60.6-0.4-1.20.30.3-1.51.5-0.00.6-0.40.80.1-0.4
Intermittent access day 1 total infusions0.10.10.4-0.1-0.60.40.70.3-0.50.50.2-0.1-0.10.40.40.5-0.50.20.1-0.60.6-0.1-0.1-0.10.1-0.10.2
Intermittent access day 15 total infusions0.30.31.00.0-1.00.91.00.7-0.80.80.3-0.2-0.20.50.50.6-0.90.30.4-0.70.7-0.2-0.1-0.10.20.10.2
Intermittent access terminal intake (last 3 days)0.60.71.4-0.1-1.21.01.10.8-0.80.81.0-0.90.51.01.01.0-0.81.01.0-0.60.6-0.8-0.50.4-0.2-0.30.9
Intermittent access total infusions0.20.30.8-0.1-0.90.70.90.7-0.70.70.4-0.3-0.00.50.50.6-0.60.40.5-0.60.6-0.3-0.10.10.1-0.00.4
Intermittent access day 1 locomotion0.30.31.00.7-1.00.71.00.7-0.80.80.4-0.30.00.50.5-0.0-1.00.40.1-0.80.8-0.30.1-0.20.30.0-0.0
Intermittent access day 15 total locomotion0.50.61.60.4-0.50.30.40.2-0.20.21.2-1.00.51.01.00.70.01.20.90.1-0.1-1.1-0.70.9-0.6-0.71.3
Intermittent access total locomotion0.30.40.90.6-0.80.70.80.7-0.50.50.9-0.80.40.70.70.5-0.50.90.7-0.50.5-0.8-0.30.5-0.1-0.30.7
Intermittent access standard deviation0.70.83.20.11.2-0.6-1.2-0.70.9-0.90.2-0.50.80.20.21.11.10.20.71.8-1.8-0.4-1.00.7-1.0-0.30.4
Left kidney weight0.82.24.32.1-0.0-0.7-0.1-1.31.1-1.11.9-1.61.32.02.00.90.91.91.50.7-0.7-1.9-1.51.8-1.6-2.11.8
Right kidney weight0.41.23.21.3-0.1-0.8-0.0-1.10.9-0.91.6-1.10.31.41.40.10.91.60.90.3-0.3-1.6-0.81.5-1.0-1.81.5
Cocaine induced anxiety2.52.811.71.9-1.32.11.11.2-1.31.31.4-2.03.02.02.03.4-1.31.52.5-0.10.1-1.1-1.90.6-1.30.00.8
Post-drug Anxiety0.40.52.90.6-0.01.0-0.10.7-0.50.50.0-0.71.60.00.01.7-0.60.11.00.1-0.1-0.0-0.70.1-0.50.7-0.1
Baseline Anxiety3.23.48.9-1.62.4-2.6-2.2-1.62.0-2.0-1.72.0-2.4-2.2-2.2-3.02.0-1.7-2.21.2-1.21.11.5-0.10.80.1-0.9
Tail length2.47.222.92.4-4.84.14.63.1-3.33.32.0-2.12.22.22.11.7-3.51.92.0-3.63.6-1.2-0.3-0.20.70.20.6
Length with tail1.96.915.13.6-3.02.02.60.9-1.01.03.9-3.63.03.53.52.6-1.23.63.4-1.71.7-3.2-2.42.1-1.6-2.12.4
Length without tail2.86.211.22.41.2-1.9-1.5-2.32.5-2.53.2-2.61.62.52.51.52.52.92.41.9-1.9-3.2-2.83.2-3.0-3.32.8
Times rat made contact with spout1.31.53.81.9-0.30.70.10.30.2-0.21.5-1.71.91.21.21.90.41.51.70.8-0.8-1.4-1.61.0-1.3-0.70.9
Lifetime Intake0.10.10.2-0.0-0.50.20.50.3-0.20.20.4-0.3-0.10.40.40.4-0.30.40.5-0.30.3-0.4-0.10.3-0.0-0.30.4
Liver weight, left0.50.91.60.90.9-0.8-1.0-1.21.1-1.10.7-0.60.21.01.00.90.90.60.71.1-1.1-0.8-1.11.1-1.3-1.00.8
Liver weight, right2.33.87.92.8-1.90.71.70.10.0-0.02.7-2.72.32.62.61.3-0.22.72.8-0.90.9-2.5-1.62.1-1.3-2.02.2
Locomotor activity0.20.41.0-1.01.0-0.7-1.0-0.40.7-0.7-0.60.4-0.1-0.8-0.7-0.60.4-0.6-0.70.5-0.50.50.3-0.30.10.3-0.0
Locomotor testing distance0.40.71.7-1.20.6-0.3-0.50.00.1-0.1-1.10.9-1.0-1.0-1.0-1.2-0.2-1.0-1.3-0.10.11.01.0-0.90.80.8-0.6
Locomotor testing rearing0.71.02.8-1.7-0.10.50.21.1-0.90.9-1.11.0-0.9-1.4-1.3-1.0-0.6-1.1-1.0-0.20.21.21.2-1.21.21.3-0.8
Locomotion in novel chamber0.40.41.2-0.3-0.20.20.20.4-0.40.4-0.60.8-1.1-0.4-0.4-1.0-0.4-0.6-0.9-0.70.70.70.9-0.90.80.5-0.9
Locomotion in novel chamber post-restriction0.70.92.91.7-1.20.81.10.6-0.60.61.1-1.00.91.21.21.4-0.51.11.2-0.40.4-0.9-0.90.7-0.6-0.60.3
Fecal boli incidents, locomotor time 10.30.30.8-0.90.6-0.6-0.5-0.40.5-0.5-0.40.6-0.7-0.5-0.5-0.90.4-0.4-0.90.0-0.00.40.5-0.40.30.1-0.4
Change in fecal boli incidents, locomotor task1.91.84.9-1.22.2-1.9-2.2-1.71.9-1.9-0.30.10.3-0.7-0.70.52.1-0.30.12.1-2.1-0.1-0.80.8-1.1-0.50.9
Time >=10cm from walls, locomotor time 10.70.71.9-1.0-0.90.51.01.1-0.30.3-0.10.5-0.9-1.3-1.3-0.7-0.6-0.2-0.7-1.41.40.30.8-0.41.10.6-0.4
Bouts of movement, locomotor time 10.80.92.4-0.31.5-1.4-1.5-1.11.0-1.0-1.01.1-1.0-0.9-0.9-0.80.7-1.0-0.81.0-1.00.70.4-0.30.00.1-0.8
Total resting periods, locomotor time 11.01.13.7-0.01.9-1.7-1.9-1.61.4-1.4-0.80.8-0.8-0.7-0.7-0.61.2-0.7-0.61.4-1.40.30.10.2-0.4-0.2-0.5
Rest time, locomotor task time 10.50.61.10.60.9-0.8-0.9-1.10.9-0.90.4-0.50.40.60.60.41.00.50.20.8-0.8-0.7-0.81.0-0.9-0.80.7
Distance moved, locomotor task time 10.40.51.8-0.1-1.10.91.10.9-0.80.80.10.1-0.40.20.20.0-1.20.0-0.1-1.31.30.10.3-0.60.50.3-0.3
Vertical activity count, locomotor time 11.41.54.2-0.1-1.81.61.81.8-1.61.6-0.10.1-0.5-0.6-0.6-0.4-1.9-0.1-0.1-2.02.00.40.8-1.11.20.9-1.0
Time >=10cm from walls, locomotor time 20.50.51.6-0.0-0.0-0.70.1-0.51.0-1.01.2-0.7-0.20.50.5-0.30.71.20.30.3-0.3-1.3-0.40.9-0.4-1.31.0
Bouts of movement, locomotor time 20.70.81.9-0.31.0-1.0-0.9-0.60.6-0.6-1.11.1-1.4-1.1-1.1-1.20.4-1.1-1.00.6-0.60.80.8-0.60.50.3-1.2
Total resting periods, locomotor time 20.50.62.0-0.20.6-0.8-0.5-0.30.4-0.4-0.91.0-1.4-1.0-1.0-1.30.0-0.9-0.80.2-0.20.70.9-0.70.60.3-1.1
Rest time, locomotor task time 20.20.20.70.90.3-0.7-0.3-0.40.6-0.60.5-0.3-0.20.10.1-0.20.80.60.40.2-0.2-0.6-0.30.6-0.4-0.60.2
Distance moved, locomotor task time 20.10.10.4-0.3-0.30.10.3-0.20.0-0.00.3-0.1-0.20.60.6-0.1-0.60.3-0.4-0.60.6-0.3-0.0-0.2-0.0-0.40.3
Vertical activity count, locomotor time 20.60.61.8-0.7-0.90.60.90.8-0.70.7-0.30.4-0.7-0.5-0.5-0.9-1.1-0.4-0.8-1.41.40.30.9-0.81.00.5-0.5
Light reinforcement 11.12.05.4-0.1-2.22.12.32.2-2.22.2-0.20.4-0.5-0.3-0.2-0.4-1.9-0.1-0.3-2.02.00.51.1-1.31.51.1-0.9
Light reinforcement 21.21.65.11.2-2.31.72.21.6-1.71.70.9-1.11.21.01.00.4-1.51.01.0-1.51.5-0.6-0.0-0.10.4-0.10.4
Bone: marrow area0.51.11.8-1.0-0.70.70.80.9-1.11.1-1.11.1-0.9-0.8-0.8-0.9-1.0-1.2-0.9-1.41.41.21.2-1.01.31.2-0.7
Bone: maximum diameter1.01.94.22.0-1.71.11.50.4-0.50.51.8-1.81.81.91.91.3-0.61.71.7-0.80.8-1.5-1.21.2-0.8-1.11.3
Bone: maximum force2.13.79.32.2-3.12.82.81.8-2.12.11.7-1.92.02.12.12.3-2.11.71.9-1.91.9-1.2-1.20.4-0.4-0.20.8
Bone: maximum moment2.44.29.72.4-3.13.02.91.9-2.22.21.9-2.02.22.32.32.7-2.21.82.0-1.81.8-1.3-1.50.4-0.6-0.10.9
Mean time between licks in bursts0.60.81.7-0.31.3-1.3-1.2-1.10.9-0.9-1.11.1-1.2-0.7-0.7-1.30.8-1.0-1.20.5-0.50.70.7-0.30.30.0-0.6
Mean num. licks in bursts0.30.31.70.70.30.5-0.50.1-0.10.10.3-0.50.90.30.31.30.20.20.40.9-0.9-0.1-0.80.0-0.70.3-0.0
Cd content in liver1.61.74.0-1.81.2-0.5-1.10.2-0.20.2-2.01.8-1.5-1.8-1.8-1.30.1-2.0-1.60.4-0.41.81.4-1.31.11.4-1.2
Co content in liver0.30.41.1-1.00.20.3-0.10.6-0.60.6-0.70.7-0.6-0.7-0.7-0.2-0.3-0.8-0.4-0.00.00.80.6-0.80.50.9-0.5
Cu content in liver1.11.43.20.90.4-0.2-0.6-0.60.7-0.71.4-1.51.81.01.01.70.81.21.51.1-1.1-1.2-1.71.3-1.6-1.01.2
Fe content in liver0.50.61.6-0.70.9-0.6-0.8-0.50.3-0.3-0.91.1-1.0-0.8-0.8-0.90.1-0.9-1.3-0.10.10.80.8-0.80.50.4-0.8
K content in liver1.11.13.80.8-2.01.41.91.3-1.31.30.9-0.80.60.90.80.3-1.10.81.0-1.31.3-0.50.00.10.4-0.10.5
Mg content in liver0.90.92.5-0.6-1.30.71.51.3-1.11.1-0.20.4-0.8-0.5-0.5-1.1-0.8-0.3-0.4-1.61.60.51.2-0.61.30.5-0.3
Mn content in liver0.50.51.30.8-0.50.00.4-0.00.1-0.11.1-1.11.10.80.80.50.41.01.10.1-0.1-0.9-0.70.8-0.6-0.80.9
Na content in liver0.20.20.60.6-0.1-0.30.1-0.40.4-0.40.6-0.50.60.60.60.10.30.60.80.1-0.1-0.6-0.40.6-0.4-0.70.5
Rb content in liver0.81.13.0-0.6-1.41.51.51.7-1.51.5-0.20.2-0.1-0.4-0.5-0.1-1.3-0.10.0-1.61.60.50.7-0.71.11.0-0.4
Se content in liver0.20.20.9-0.2-0.70.80.71.0-0.80.80.2-0.20.4-0.2-0.20.2-0.40.00.3-0.70.70.10.1-0.00.30.40.1
Sr content in liver1.61.43.51.11.3-1.0-1.4-1.41.3-1.30.7-0.80.90.80.81.21.20.80.91.9-1.9-1.0-1.51.2-1.6-1.10.6
Zn content in liver1.31.53.61.50.3-1.2-0.4-1.21.4-1.41.5-1.10.81.21.20.21.41.41.00.9-0.9-1.6-1.01.6-1.2-1.91.1
Bone: minimum diameter1.42.75.52.0-2.22.32.01.4-1.41.41.7-2.02.31.91.82.3-1.01.62.1-1.01.0-1.2-1.40.9-0.7-0.31.1
Time in familiar zone, hab. session 10.10.10.3-0.40.50.0-0.50.00.1-0.1-0.40.2-0.5-0.4-0.40.40.1-0.3-0.30.3-0.30.3-0.1-0.2-0.10.4-0.4
Time in novel zone, hab. session 10.00.00.1-0.1-0.30.10.40.2-0.20.20.1-0.00.30.00.0-0.4-0.20.10.1-0.10.1-0.00.2-0.20.2-0.10.1
Total zone transitions, hab. session 10.71.02.1-1.20.30.1-0.20.4-0.50.5-1.41.2-1.1-1.2-1.3-0.8-0.7-1.4-1.2-0.00.01.41.1-1.21.01.2-1.1
Total locomotion distance, hab. session 11.21.73.3-0.9-0.81.40.91.5-1.71.7-1.31.0-0.8-1.1-1.1-0.4-1.8-1.3-0.9-0.90.91.71.3-1.81.51.8-1.4
Locomotion velocity, hab. session 11.11.63.5-0.7-0.81.40.91.4-1.71.7-1.30.9-0.7-0.9-0.9-0.3-1.9-1.2-0.8-1.11.11.61.2-1.71.41.7-1.4
Time in familiar zone, hab. session 20.80.81.7-0.90.30.3-0.20.4-0.50.5-1.31.1-0.9-1.0-1.0-0.5-0.7-1.2-1.1-0.60.61.20.9-1.20.81.2-1.3
Time in novel zone, hab. session 20.20.20.6-0.00.2-0.6-0.2-0.50.6-0.60.6-0.30.10.20.2-0.30.80.50.30.7-0.7-0.6-0.20.7-0.3-0.70.7
Total zone transitions, hab. session 21.92.44.3-1.8-0.50.60.71.2-1.21.2-1.81.7-1.5-1.7-1.7-1.8-1.4-1.8-1.6-1.41.41.92.1-1.92.01.7-1.5
Total locomotion distance, hab. session 21.92.54.2-1.0-1.61.51.81.8-2.02.0-1.11.0-0.8-1.0-1.0-1.3-2.0-1.2-0.9-2.02.01.51.8-1.82.11.6-1.2
Locomotion velocity, hab. session 21.72.34.5-0.7-1.81.72.01.9-2.12.1-0.90.8-0.7-0.8-0.8-0.9-2.1-0.9-0.7-2.12.11.31.6-1.61.91.5-1.1
Novel to familiar place preference ratio1.21.24.70.4-0.91.50.71.3-0.80.81.2-1.62.00.60.62.2-0.41.21.50.3-0.3-0.9-1.30.5-0.80.20.8
Novelty place preference1.21.24.80.5-0.81.40.71.2-0.60.61.3-1.71.90.60.62.2-0.31.31.60.4-0.4-1.0-1.40.6-0.90.10.8
Time in novel zone, NPP test0.90.93.50.2-0.81.40.71.3-0.70.71.1-1.41.60.40.31.9-0.41.11.30.2-0.2-0.7-1.10.4-0.60.30.6
Total zone transitions, NPP test2.23.15.8-1.9-0.50.40.81.0-1.11.1-2.01.9-2.2-1.8-1.8-2.3-1.6-2.0-1.9-1.71.72.12.4-2.12.31.7-1.7
Total locomotion distance, NPP test2.83.86.7-1.7-1.51.41.72.0-2.12.1-1.81.6-1.7-1.7-1.7-1.9-2.3-1.9-1.6-2.22.22.22.4-2.42.62.1-1.7
Locomotion velocity, NPP test2.13.04.9-1.4-1.51.51.71.9-2.02.0-1.51.3-1.3-1.4-1.4-1.4-2.2-1.6-1.3-2.02.01.92.0-2.12.21.9-1.5
Intraocular pressure0.30.51.4-0.5-0.91.10.90.8-1.21.2-0.30.2-0.1-0.3-0.40.1-0.8-0.3-0.3-0.80.80.60.3-0.60.60.9-0.4
Delta distance traveled before/after self-admin1.61.83.2-1.6-0.20.40.31.1-0.80.8-1.41.7-1.7-1.7-1.7-1.2-0.9-1.4-1.6-0.90.91.51.6-1.81.61.4-1.4
Delta ambulatory time before/after self-admin1.41.64.0-1.70.4-0.2-0.20.6-0.20.2-1.31.7-2.0-1.8-1.8-1.6-0.3-1.4-1.8-0.40.41.31.6-1.41.41.1-1.1
Parametrial fat weight0.81.53.31.5-1.81.51.71.0-1.01.01.4-1.30.81.31.31.5-1.51.21.1-1.61.6-1.0-0.80.5-0.3-0.40.4
Pavlov. Cond. lever latency4.35.59.5-2.90.00.80.21.5-1.51.5-2.92.9-3.1-2.9-2.9-1.7-1.7-3.0-2.8-1.11.13.02.6-2.92.62.9-2.9
Pavlov. Cond. magazine entry latency2.12.76.82.6-0.60.80.3-0.20.1-0.11.9-2.32.42.32.32.30.32.02.10.3-0.3-1.8-2.11.6-1.8-1.31.5
Pavlov. Cond. change in total contacts1.01.02.80.70.5-0.0-0.7-0.40.5-0.50.9-1.31.70.90.91.40.81.11.21.1-1.1-1.0-1.51.1-1.4-0.61.2
Pavlov. Cond. index score3.24.09.12.9-1.20.80.9-0.10.1-0.12.5-2.83.02.82.82.20.32.62.7-0.10.1-2.5-2.32.1-1.9-1.92.1
Pavlov. Cond. latency score3.84.910.63.1-0.80.20.5-0.70.7-0.72.8-3.03.23.02.92.20.92.92.90.5-0.5-2.8-2.52.5-2.3-2.42.5
Pavlov. Cond. lever contacts2.32.75.42.2-0.4-0.30.2-0.80.8-0.82.0-2.22.32.12.11.21.02.22.00.4-0.4-2.2-1.72.0-1.6-2.02.0
Pavlov. Cond. magazine entry number2.63.36.9-2.60.2-0.40.10.7-0.50.5-2.02.4-2.5-2.4-2.4-2.5-0.7-2.2-2.2-0.90.92.12.5-2.02.21.6-1.7
Pavlov. Cond. intertrial magazine entries0.91.12.4-0.8-1.01.01.21.2-1.51.5-0.60.8-1.0-0.8-0.8-0.5-1.4-0.7-0.7-1.41.40.91.0-1.11.21.1-1.1
Pavlov. Cond. lever-magazine prob. diff.2.93.68.32.7-1.21.00.90.1-0.10.12.4-2.72.92.62.62.30.22.52.5-0.20.2-2.3-2.21.9-1.8-1.61.9
Pavlov. Cond. response bias2.83.47.22.7-0.40.30.1-0.60.5-0.52.2-2.42.62.52.52.30.82.32.30.6-0.6-2.3-2.42.0-2.1-1.81.8
Pavlov. Cond. lever latency2.02.75.61.21.5-2.0-1.6-2.32.3-2.31.2-1.11.01.11.10.42.41.31.11.8-1.8-1.6-1.42.0-1.8-2.11.5
Pavlov. Cond. magazine entry latency3.13.56.8-2.60.60.1-0.40.9-0.70.7-2.42.4-2.1-2.5-2.5-1.9-1.0-2.5-2.4-0.50.52.52.2-2.32.02.2-2.1
Pavlov. Cond. change in total contacts2.53.46.1-2.2-0.31.10.51.6-1.71.7-2.22.1-1.9-2.1-2.1-1.1-1.8-2.2-2.2-1.11.12.41.9-2.52.02.5-2.1
Pavlov. Cond. index score2.73.56.6-2.1-0.31.30.51.8-1.71.7-2.12.0-1.8-2.1-2.1-1.0-1.9-2.3-2.1-1.11.12.41.9-2.52.02.6-2.2
Pavlov. Cond. latency score2.73.46.2-2.1-0.51.30.71.8-1.71.7-2.01.9-1.7-2.0-2.0-1.1-2.0-2.2-2.0-1.21.22.31.9-2.42.12.5-2.1
Pavlov. Cond. lever contacts2.23.16.1-1.2-1.72.21.92.5-2.42.4-1.11.1-1.1-1.1-1.1-0.5-2.5-1.2-1.1-2.12.11.61.5-2.11.92.1-1.5
Pavlov. Cond. magazine entry number3.34.17.52.7-0.3-0.60.1-1.31.1-1.12.5-2.52.22.72.71.81.22.62.50.8-0.8-2.6-2.32.5-2.2-2.52.3
Pavlov. Cond. intertrial magazine entries0.70.92.31.0-1.51.21.40.9-1.11.11.0-1.10.61.11.10.8-0.71.01.0-1.01.0-0.8-0.50.4-0.1-0.30.7
Pavlov. Cond. lever-magazine prob. diff.3.03.87.1-2.3-0.21.20.41.7-1.61.6-2.32.2-2.0-2.2-2.2-1.1-1.9-2.5-2.3-1.01.02.62.0-2.62.12.7-2.3
Pavlov. Cond. response bias2.23.05.1-1.8-0.91.61.12.0-1.91.9-1.61.6-1.5-1.7-1.7-0.9-2.0-1.8-1.7-1.51.52.01.8-2.22.02.3-1.8
Time in closed arm before self-admin0.50.62.30.51.0-0.8-1.0-1.20.9-0.9-0.60.4-0.0-0.1-0.11.00.8-0.5-0.31.5-1.50.3-0.6-0.1-0.7-0.1-0.6
Time in closed arm after self-admin2.62.75.52.01.8-2.0-1.9-2.12.4-2.41.3-1.00.30.80.80.91.91.30.82.0-2.0-1.7-1.61.9-1.9-1.80.7
Time in open arm before self-admin0.70.72.30.4-0.2-0.50.2-0.10.6-0.61.5-1.20.20.60.6-1.20.41.50.7-0.50.5-1.4-0.01.2-0.1-1.21.5
Time in open arm after self-admin0.50.61.5-1.2-0.40.40.50.7-0.90.9-0.80.7-0.5-0.6-0.6-1.1-0.6-0.8-0.8-0.70.70.91.0-0.90.90.7-0.3
Bone: periosteal estimation0.81.74.91.2-2.22.02.11.4-1.51.51.0-1.11.21.21.21.3-1.40.91.1-1.71.7-0.6-0.50.30.00.10.6
Bone: periosteal perimeter2.74.511.23.3-1.61.01.2-0.20.1-0.12.7-2.82.73.03.02.70.02.72.7-0.20.2-2.5-2.52.2-2.0-1.92.0
Bone: post-yield work0.30.40.8-0.4-0.50.30.60.5-0.50.5-0.50.7-0.7-0.4-0.4-0.9-0.8-0.7-0.7-0.70.70.70.9-0.80.90.5-0.7
Progressive ratio test 1 active lever presses0.50.51.50.7-1.21.01.21.0-0.80.80.6-0.60.40.40.40.7-1.00.60.5-1.01.0-0.4-0.10.00.20.10.3
Progressive ratio test 1 breakpoint0.60.61.80.7-1.31.21.31.1-0.90.90.6-0.60.30.40.40.9-1.10.50.5-1.11.1-0.4-0.1-0.10.20.10.1
Progressive ratio test 1 inactive lever presses1.41.54.30.8-2.12.12.01.8-1.91.90.4-0.40.40.70.70.8-1.80.40.4-1.61.6-0.00.1-0.50.60.6-0.2
Progressive ratio test 2 active lever presses0.30.30.90.4-0.60.40.60.4-0.20.20.9-0.80.20.70.70.7-0.10.90.7-0.20.2-0.8-0.50.7-0.3-0.50.8
Progressive ratio test 2 breakpoint0.30.30.80.3-0.90.50.90.6-0.60.60.8-0.60.00.50.50.4-0.40.80.5-0.50.5-0.7-0.20.4-0.0-0.30.6
Progressive ratio test 2 inactive lever presses0.30.41.10.2-0.50.50.40.3-0.40.40.8-0.80.70.80.80.9-0.50.81.10.0-0.0-0.7-0.60.5-0.4-0.40.8
Incentive Sensitization - Responses0.10.10.40.5-0.20.00.2-0.00.1-0.10.5-0.3-0.50.40.40.60.20.5-0.0-0.30.3-0.5-0.30.4-0.3-0.40.2
Incentive Sensitization - Breakpoint0.10.10.40.5-0.1-0.00.1-0.10.1-0.10.6-0.4-0.40.50.50.60.30.60.1-0.10.1-0.6-0.40.5-0.4-0.40.2
Sum of active levers in priming session hrs 5-61.11.13.6-0.3-0.11.60.00.9-1.31.3-1.50.51.5-0.6-0.61.5-1.1-1.4-0.10.3-0.31.6-0.0-1.40.31.9-0.9
Progressive ratio0.20.21.7-1.30.7-0.5-0.7-0.10.0-0.0-0.40.3-0.1-0.6-0.6-0.40.6-0.5-0.00.5-0.50.40.2-0.00.00.20.2
Food seeking constrained by brief footshock0.10.20.6-0.60.8-0.3-0.8-0.20.2-0.2-0.0-0.00.1-0.3-0.30.40.2-0.00.30.7-0.70.1-0.3-0.1-0.40.2-0.0
Seeking ratio, punishment vs. effort0.10.10.80.6-0.50.50.50.3-0.40.4-0.10.2-0.3-0.0-0.00.1-0.90.1-0.3-0.50.50.10.1-0.50.20.3-0.6
Retroperitoneal fat weight2.17.019.41.8-4.44.44.23.7-3.73.71.5-1.81.61.61.62.5-3.51.51.7-3.73.7-0.7-0.6-0.50.50.90.1
Reaction time number correct5.98.414.0-3.0-1.92.22.33.1-2.92.9-2.72.9-2.7-2.8-2.8-2.6-2.7-2.5-2.9-3.33.33.03.5-3.53.73.2-2.5
Reaction time mean minus median0.70.91.60.80.6-0.9-0.7-1.01.1-1.11.1-0.80.50.90.80.51.21.10.81.0-1.0-1.2-1.01.3-1.1-1.21.0
Reaction time mean minus median AUC0.60.82.01.1-0.2-0.60.1-0.50.6-0.61.4-0.90.31.21.10.10.81.40.90.3-0.3-1.4-0.71.2-0.8-1.41.1
Reaction time num false alarms0.30.41.2-0.10.7-0.4-0.7-0.60.4-0.4-0.90.8-0.5-0.5-0.4-0.20.1-0.8-1.01.0-1.00.60.3-0.70.10.4-1.1
Reaction time num false alarms AUC0.50.61.3-0.41.0-0.7-0.9-0.80.7-0.7-0.91.0-0.8-0.8-0.7-0.70.3-1.0-1.20.9-0.90.70.5-0.60.30.4-1.1
Reaction time trials correct on left5.98.414.0-3.0-1.92.22.33.1-2.92.9-2.72.9-2.7-2.8-2.8-2.6-2.7-2.5-2.9-3.33.33.03.5-3.53.73.2-2.5
Reaction time trials on left6.18.714.4-3.1-2.02.22.33.2-3.03.0-2.72.9-2.8-2.8-2.8-2.7-2.7-2.5-2.9-3.43.43.03.5-3.53.83.2-2.5
Reaction time mean0.20.30.9-0.5-0.80.80.80.9-0.90.9-0.00.1-0.6-0.2-0.30.1-0.7-0.0-0.3-0.80.80.20.2-0.30.50.6-0.2
Reaction time mean AUC0.40.61.3-0.7-1.00.91.01.1-1.11.1-0.20.4-1.0-0.4-0.5-0.3-0.9-0.2-0.6-1.11.10.40.6-0.50.80.7-0.3
Median of all reaction times0.50.71.5-0.8-0.91.01.01.2-1.21.2-0.40.5-0.9-0.6-0.6-0.1-1.1-0.4-0.6-1.11.10.60.6-0.70.91.0-0.5
Reaction time omissions0.20.30.90.1-0.90.80.80.8-0.90.9-0.00.2-0.30.20.1-0.3-0.7-0.1-0.1-0.90.90.20.5-0.30.60.4-0.1
Reaction time false alarm rate1.52.16.51.11.8-1.7-1.9-2.22.0-2.00.4-0.50.70.70.70.71.60.30.42.6-2.6-0.8-1.31.2-1.6-1.20.3
Reaction time premature initiation rate0.70.92.3-1.01.5-1.0-1.4-0.70.6-0.6-1.31.1-0.6-1.0-1.0-0.80.4-1.3-1.01.1-1.11.10.5-0.90.20.6-0.9
Reaction time premature initiations2.73.96.9-2.60.30.3-0.11.1-1.01.0-2.62.5-2.1-2.4-2.5-2.1-1.2-2.5-2.5-0.80.82.62.3-2.62.22.3-2.2
Std. dev. reaction times0.10.20.8-0.70.5-0.5-0.4-0.20.3-0.3-0.30.6-0.9-0.5-0.6-0.60.3-0.4-0.60.1-0.10.30.4-0.10.30.2-0.2
Reaction time trials completed6.18.714.4-3.1-2.02.22.33.2-3.03.0-2.72.9-2.8-2.8-2.8-2.7-2.7-2.5-2.9-3.43.43.03.5-3.53.83.2-2.5
Reaction time trials AUC6.08.614.3-3.0-2.02.22.43.2-3.03.0-2.72.8-2.7-2.8-2.8-2.6-2.8-2.5-2.9-3.43.43.03.5-3.53.83.2-2.5
Run reversals in cocaine runway, females2.32.24.9-2.20.30.0-0.20.4-0.40.4-2.22.2-1.8-1.8-1.8-1.3-0.4-2.1-2.2-0.40.42.11.6-1.81.51.6-1.5
Run reversals in cocaine runway, males1.81.75.00.8-0.40.30.2-0.10.1-0.11.7-1.91.81.51.51.80.51.72.20.6-0.6-1.6-1.71.6-1.4-1.01.8
Latency to leave start box in cocaine runway0.30.41.6-0.70.3-0.4-0.3-0.40.2-0.2-0.70.9-0.9-0.8-0.8-0.70.2-0.8-1.3-0.10.10.60.5-0.50.40.3-0.7
Latency to leave start box in cocaine runway, F0.60.61.8-1.0-0.2-0.10.3-0.0-0.10.1-0.71.0-1.2-0.9-0.9-1.4-0.3-0.9-1.3-0.50.50.71.1-0.91.00.4-0.7
Latency to leave start box in cocaine runway, M0.10.10.30.50.2-0.2-0.2-0.20.3-0.30.3-0.20.20.00.00.60.40.2-0.30.2-0.2-0.3-0.40.3-0.4-0.2-0.2
Std. dev. time between licks in bursts3.13.77.9-0.1-2.01.72.22.0-2.22.2-1.41.4-1.6-1.2-1.2-1.5-2.5-1.2-1.7-2.82.81.52.1-2.32.41.8-2.1
Total sessions with >9 infusions0.30.30.7-0.80.4-0.9-0.4-0.50.8-0.80.7-0.2-0.6-0.2-0.2-0.40.50.50.30.3-0.3-0.7-0.00.8-0.1-0.70.7
Short access day 1 total inactive lever presses0.20.31.20.4-0.60.00.7-0.0-0.40.40.4-0.0-0.50.70.7-1.1-0.40.4-0.0-0.80.8-0.30.50.10.5-0.50.5
Short access day 10 total inactive lever presses1.31.53.41.3-1.71.91.61.5-1.51.51.1-1.21.41.21.21.6-1.01.21.3-0.80.8-0.8-0.80.5-0.30.10.7
Short access day 1 total infusions0.50.61.9-0.61.2-1.4-1.2-1.01.1-1.1-0.20.4-0.8-0.5-0.5-0.90.9-0.3-0.20.8-0.8-0.00.20.3-0.1-0.40.2
Short access day 10 total infusions0.30.41.20.7-0.70.50.70.5-0.40.40.7-0.80.80.80.81.1-0.10.70.8-0.00.0-0.6-0.50.4-0.4-0.30.6
Short access total infusions0.00.00.1-0.10.1-0.2-0.1-0.10.2-0.20.2-0.1-0.20.00.00.20.10.20.20.2-0.2-0.3-0.10.2-0.1-0.30.2
Short access day 1 locomotion0.80.91.80.40.7-1.2-0.8-0.91.1-1.11.0-0.80.40.70.70.01.21.00.71.1-1.1-1.1-0.71.1-0.9-1.31.1
Short access day 10 total locomotion0.91.01.90.30.8-0.8-0.9-0.91.0-1.01.1-1.21.00.80.80.61.01.10.91.0-1.0-1.2-1.11.3-1.2-1.11.4
Short access total locomotion1.21.22.20.51.0-1.4-1.0-1.21.3-1.31.2-1.00.30.80.80.21.41.10.71.2-1.2-1.3-0.91.5-1.1-1.51.3
One hour access (0.3 mA shock)0.60.72.2-0.0-1.41.41.41.5-1.21.20.4-0.40.10.00.00.8-1.00.40.5-1.11.1-0.10.1-0.10.50.50.1
Compulsive drug intake0.70.71.50.6-0.81.20.81.0-1.11.1-0.60.5-0.2-0.2-0.20.5-0.9-0.6-0.4-1.01.00.70.5-0.90.71.0-1.2
One hour access (shock baseline)0.30.31.00.1-0.80.10.80.4-0.20.20.9-0.7-0.00.70.7-0.3-0.20.90.8-0.30.3-0.9-0.10.80.0-0.71.0
Social response proportion0.40.41.1-1.10.1-0.1-0.00.5-0.10.1-0.80.8-0.7-1.0-0.9-1.00.3-0.7-0.8-0.10.10.80.9-0.50.80.7-0.3
Social responses0.10.20.5-0.4-0.20.10.20.6-0.20.2-0.30.1-0.1-0.6-0.5-0.60.1-0.3-0.2-0.70.70.30.5-0.30.50.3-0.1
Social time0.30.41.2-1.1-0.10.20.20.6-0.50.5-0.70.7-0.6-1.1-1.0-0.60.3-0.7-0.6-0.20.20.70.7-0.20.70.7-0.3
Soleus weight0.71.95.11.9-2.31.62.21.1-1.31.31.5-1.51.11.71.71.0-1.51.41.6-1.41.4-1.1-0.70.5-0.2-0.70.6
Bone: stiffness0.30.51.60.8-1.30.91.20.5-0.80.80.5-0.60.70.90.90.5-0.90.50.6-1.01.0-0.4-0.30.10.0-0.20.4
Tibialis anterior weight0.10.31.1-0.5-0.70.20.80.4-0.70.7-0.20.3-0.3-0.4-0.4-0.7-0.5-0.40.1-1.11.10.40.6-0.10.70.3-0.1
Time to tail flick, vehicle, before self-admin0.10.10.60.8-0.40.10.40.1-0.50.50.10.00.10.40.4-0.10.50.10.3-0.00.0-0.10.10.30.1-0.20.3
Time to tail flick, vehicle, after self-admin1.01.04.10.21.4-2.0-1.3-1.61.8-1.8-0.10.5-0.6-0.0-0.0-1.11.4-0.1-0.51.0-1.0-0.30.20.3-0.3-1.1-0.2
Time to tail flick, test, before self-admin0.30.30.50.60.3-0.2-0.3-0.40.3-0.30.7-0.70.60.40.40.60.10.60.70.5-0.5-0.6-0.60.5-0.6-0.50.4
Time to tail flick, test, after self-admin0.30.31.0-0.20.4-0.4-0.4-0.30.7-0.70.8-0.70.5-0.0-0.10.10.60.70.90.4-0.4-0.8-0.20.8-0.3-0.51.0
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.80.0-0.20.00.30.3-0.3-0.30.4-0.5-0.6-0.6-0.9-0.4-0.3-0.7-0.40.40.30.7-0.60.60.2-0.6
Delta time to tail flick, test, before/after SA0.30.31.1-1.10.7-0.6-0.7-0.40.8-0.80.0-0.00.1-0.6-0.50.00.9-0.00.00.6-0.6-0.2-0.10.4-0.2-0.10.6
Tibia length4.713.229.05.4-3.83.03.21.1-1.21.24.9-4.74.25.05.05.0-1.54.64.3-0.90.9-4.1-4.23.0-3.0-2.72.8
Ambulatory time before self-admin1.21.25.80.6-1.11.61.01.0-1.21.20.6-1.32.41.01.02.0-0.70.71.7-0.40.4-0.4-1.00.5-0.50.30.8
Ambulatory time after self-admin0.70.72.0-0.9-0.81.30.81.4-1.11.1-0.60.20.6-0.8-0.80.5-0.9-0.6-0.0-0.90.90.80.6-0.90.81.2-0.4
Bone: tissue strength1.00.92.60.1-1.61.51.61.6-1.51.50.3-0.20.10.10.20.2-1.60.20.3-1.31.30.20.4-0.80.70.6-0.3
Total heroin consumption0.30.32.5-0.10.30.6-0.4-0.1-0.30.30.0-0.61.60.10.11.30.30.00.90.7-0.70.1-0.60.1-0.50.40.4
Bone: trabecular number0.00.00.20.0-0.2-0.20.2-0.20.1-0.10.3-0.2-0.00.10.0-0.1-0.10.10.2-0.50.5-0.2-0.10.3-0.1-0.30.2
Bone: trabecular spacing3.34.37.0-1.9-1.52.01.72.6-2.42.4-1.91.8-1.5-1.8-1.8-1.4-2.3-1.7-1.8-2.12.12.22.4-2.62.62.6-1.9
Bone: trabecular thickness1.61.93.81.60.4-0.4-0.7-1.10.9-0.91.5-1.51.41.51.51.90.91.41.51.3-1.3-1.5-2.01.7-1.9-1.31.3
Bone: trabecular tissue density0.30.41.3-0.01.1-1.1-1.0-1.10.8-0.8-0.60.8-0.5-0.2-0.1-0.80.6-0.4-0.70.8-0.80.20.3-0.1-0.0-0.3-0.4
Water consumed over 24 hours0.81.01.60.80.6-0.5-0.7-0.71.0-1.01.0-1.21.20.70.70.71.21.01.21.3-1.3-1.1-1.01.2-1.1-1.01.2
Number of responses in last shaping day1.11.12.51.6-1.60.91.50.8-1.01.01.3-1.00.41.51.50.3-1.21.41.0-1.11.1-1.1-0.30.2-0.1-0.70.3