Hub : Genes

Tepsin

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative TSS XM_006247895.5 0.06 0.05 6.4e-04 0.04 0.04 0.05 0.04 6.5e-04 2.9e-04 1.4e-04 3.0e-04
2 NAcc alternative TSS NM_001100729.1 0.03 0.02 1.1e-04 0.01 0.02 0.01 0.02 4.6e-03 2.9e-04 2.5e-03 2.8e-04
3 OFC mRNA stability Tepsin 0.29 0.23 7.5e-03 0.09 0.05 0.07 0.07 3.7e-03 2.0e-02 9.6e-03 8.9e-03
4 NAcc alternative TSS XM_006247895.5 0.03 0.02 4.2e-04 0.02 0.02 0.02 0.02 1.1e-03 2.1e-04 6.0e-04 1.0e-03
5 PL alternative TSS XM_006247895.5 0.04 0.03 9.1e-05 0.04 0.03 0.03 0.04 1.9e-05 2.0e-04 2.2e-04 6.7e-05
6 Brain alternative TSS NM_001100729.1 0.07 0.05 5.1e-05 0.04 0.04 0.04 0.03 1.5e-04 1.1e-04 3.0e-04 4.4e-04
7 Brain alternative TSS XM_006247895.5 0.07 0.05 6.8e-05 0.04 0.04 0.04 0.04 6.9e-05 5.2e-05 2.0e-04 2.4e-04
8 NAcc gene expression Tepsin 0.13 0.07 1.7e-12 0.08 0.08 0.08 0.09 3.1e-12 2.1e-12 3.3e-12 5.7e-13
9 PL alternative TSS NM_001100729.1 0.03 0.02 4.1e-03 0.02 0.01 0.01 0.01 3.5e-03 1.5e-02 1.0e-02 1.1e-02
10 pVTA alternative TSS NM_001100729.1 0.08 0.05 1.4e-04 0.06 0.05 0.05 0.05 2.4e-05 1.1e-04 6.9e-05 7.1e-05
11 Adipose intron excision ratio chr10_105876056_105876909 0.03 0.02 2.4e-03 0.03 0.02 0.02 0.03 5.4e-04 3.0e-03 4.5e-03 8.5e-04
12 Brain intron excision ratio chr10_105876056_105876909 0.03 0.03 8.4e-03 0.01 0.02 0.02 0.02 1.4e-02 5.8e-03 6.4e-03 7.5e-03
13 Adipose mRNA stability Tepsin 0.14 0.1 1.3e-10 0.09 0.09 0.08 0.09 2.7e-10 2.4e-10 5.4e-09 5.3e-10
14 RMTg mRNA stability Tepsin 0.19 0.12 5.2e-03 0.05 0.09 0.06 0.08 1.7e-02 2.2e-03 1.0e-02 3.9e-03
15 BLA mRNA stability Tepsin 0.09 0.07 4.1e-03 0.03 0.02 0.01 0.03 6.4e-03 3.0e-02 7.3e-02 1.6e-02
16 Liver gene expression Tepsin 0.04 0.03 9.8e-04 0.02 0.02 0.01 0.02 1.7e-03 1.9e-03 1.5e-02 5.0e-03
17 NAcc mRNA stability Tepsin 0.18 0.13 3.2e-06 0.03 0.03 0.02 0.03 1.2e-05 7.3e-06 3.8e-04 2.8e-05
18 Adipose alternative TSS XM_039086442.2 0.03 0.03 3.2e-03 0.01 0.02 0.01 0.01 4.8e-02 2.9e-03 9.4e-03 2.2e-02
19 PL mRNA stability Tepsin 0.16 0.08 5.2e-11 0.08 0.1 0.09 0.09 1.1e-08 1.7e-10 3.6e-10 1.0e-09
20 Liver mRNA stability Tepsin 0.06 0.04 4.2e-05 0.02 0.04 0.04 0.04 3.5e-03 2.2e-05 6.5e-05 6.9e-05
21 LHb mRNA stability Tepsin 0.54 0.29 1.3e-03 0.05 0.05 0.05 0.07 2.7e-02 2.7e-02 2.5e-02 1.2e-02
22 Brain mRNA stability Tepsin 0.37 0.12 0.0e+00 0.24 0.26 0.25 0.25 4.4e-22 9.1e-24 1.3e-23 3.6e-23
23 BLA gene expression Tepsin 0.13 0.08 2.0e-04 0.02 0.05 0.04 0.03 2.2e-02 1.0e-03 3.5e-03 9.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.20.70.40.8-0.1-0.60.50.6-0.60.7-0.7-0.8-0.00.30.20.3-0.1-0.50.00.40.20.40.50.20.3
Area under the delay curve0.60.92.1-1.3-1.2-0.91.0-0.9-1.01.0-0.91.01.0-1.40.90.80.9-1.4-0.90.80.50.90.40.10.70.4
BMI with tail0.62.25.21.61.8-0.4-1.92.32.2-2.22.3-2.1-1.6-0.70.70.70.8-0.7-0.71.01.10.91.21.41.21.4
BMI without tail0.84.212.42.93.50.8-3.33.03.4-3.33.2-3.1-2.90.10.00.30.10.30.80.50.80.21.00.70.61.0
Body weight1.25.115.84.03.82.3-3.22.63.2-3.12.8-2.7-2.22.0-1.6-1.3-1.61.92.3-0.9-0.6-1.4-0.4-0.7-1.0-0.5
Weight adjusted by age0.61.85.12.22.10.6-2.01.31.9-1.81.9-1.8-1.31.4-1.0-0.7-1.11.41.7-0.2-0.4-0.8-0.3-0.5-0.8-0.4
Bone surface0.30.61.20.60.40.90.0-0.5-0.20.2-0.40.3-0.01.1-0.8-0.8-0.81.00.8-1.1-0.7-1.0-0.7-0.9-1.0-1.0
Bone volume0.10.20.50.70.70.4-0.40.10.4-0.30.3-0.3-0.40.5-0.3-0.3-0.30.40.3-0.5-0.2-0.4-0.2-0.2-0.4-0.3
Breakpoint value in progressive ratio session0.20.31.10.60.1-0.5-0.40.61.0-1.00.8-0.70.8-0.1-0.4-0.7-0.3-0.1-0.20.2-0.40.1-0.40.70.50.6
Number of licking bursts0.00.10.50.20.60.6-0.50.30.2-0.20.10.0-0.70.4-0.00.1-0.10.40.5-0.20.2-0.30.2-0.4-0.3-0.2
Context. condit. distance diff. score2.63.24.9-0.01.8-1.5-2.02.21.9-1.92.2-2.2-2.1-1.21.71.71.7-1.3-1.41.62.01.62.12.11.71.9
Locomotion velocity, session 12.12.36.4-1.2-2.30.52.4-2.5-2.32.3-2.22.21.90.1-0.6-0.9-0.60.00.2-1.0-1.2-0.6-1.4-1.3-0.8-1.2
Locomotion distance, session 11.51.95.7-2.4-1.2-1.70.8-0.6-0.90.8-0.40.4-0.1-1.91.71.71.7-1.8-1.71.61.41.61.31.11.51.1
Locomotion velocity, session 22.12.57.3-2.5-2.7-0.82.6-2.4-2.72.7-2.52.51.6-0.60.30.20.3-0.6-0.7-0.2-0.30.1-0.5-0.7-0.2-0.6
Locomotion distance, session 20.60.91.6-1.3-0.2-1.2-0.10.2-0.0-0.00.3-0.2-0.8-1.11.21.31.2-1.0-0.91.11.21.11.10.91.01.0
Locomotion velocity, session 30.91.03.2-1.2-1.8-0.11.7-1.6-1.61.6-1.51.51.4-0.4-0.1-0.2-0.1-0.4-0.1-0.2-0.6-0.1-0.7-0.5-0.2-0.5
Locomotion distance, session 31.21.43.9-2.0-1.9-1.21.6-1.3-1.51.5-1.21.21.1-1.31.00.71.0-1.3-1.20.70.41.00.30.40.80.5
Stereotopy head waving bouts, day 30.50.71.8-0.6-1.20.11.1-1.1-1.11.1-1.21.31.40.3-0.4-0.5-0.50.4-0.1-0.5-0.7-0.5-0.7-0.3-0.5-0.7
Stereotopy head waving duration, day 30.20.30.9-0.7-0.9-0.30.8-0.8-0.80.8-0.80.90.70.0-0.0-0.1-0.10.1-0.4-0.1-0.2-0.1-0.30.2-0.2-0.2
Locomotion velocity, session 70.40.51.2-1.0-0.7-1.10.4-0.2-0.40.3-0.20.20.1-0.90.80.70.8-0.9-1.00.70.60.80.50.70.80.7
Locomotion distance, session 73.44.39.6-2.6-0.8-3.10.20.5-0.20.10.4-0.3-0.8-2.62.72.52.7-2.7-2.72.42.42.62.22.22.52.3
Stereotopy head waving bouts, day 70.10.10.50.70.50.3-0.50.40.6-0.60.5-0.6-0.00.1-0.2-0.2-0.20.20.10.0-0.1-0.1-0.00.20.00.1
Stereotopy head waving duration, day 70.30.30.80.70.50.9-0.40.00.3-0.20.0-0.0-0.10.9-0.7-0.5-0.70.90.6-0.5-0.5-0.8-0.4-0.1-0.7-0.6
Locomotion velocity, session 81.41.73.1-1.3-0.0-1.6-0.40.70.3-0.30.6-0.6-1.0-1.51.61.71.6-1.4-1.71.61.61.51.61.71.51.4
Locomotion distance, session 84.46.49.7-0.91.7-2.5-2.32.62.1-2.22.6-2.5-2.9-2.22.72.92.7-2.2-2.32.73.12.63.13.02.62.8
Degree of sensitization distance1.21.32.90.31.3-1.0-1.51.71.4-1.41.5-1.4-1.5-0.40.90.90.9-0.4-0.71.01.20.81.21.40.91.1
Degree of sensitization stereotypy0.40.41.20.60.8-0.1-0.91.01.0-1.11.0-1.1-0.5-0.20.20.20.2-0.2-0.20.50.40.30.40.60.40.6
Conditioned locomotion2.12.57.51.92.70.4-2.62.32.5-2.52.4-2.4-2.10.40.20.40.20.3-0.20.40.90.11.01.50.40.8
Cocaine response after cond. corrected0.10.10.70.1-0.6-0.10.40.0-0.1-0.00.00.00.8-0.60.0-0.20.1-0.7-0.10.3-0.20.4-0.20.10.50.3
Cocaine response after cond. not corrected0.20.31.3-0.6-1.2-0.30.9-0.5-0.70.6-0.50.51.0-0.80.2-0.00.2-0.9-0.30.2-0.10.4-0.20.00.40.2
Cocaine response before conditioning0.30.31.8-1.3-0.7-0.70.6-0.6-0.90.9-0.80.7-0.1-0.30.50.60.4-0.4-0.50.10.40.20.30.1-0.0-0.1
Saline control response0.91.34.31.92.11.3-1.71.31.6-1.51.3-1.3-1.31.1-0.7-0.5-0.80.90.9-0.6-0.2-0.9-0.1-0.2-0.7-0.4
Bone: connectivity density0.10.20.8-0.40.3-0.6-0.30.10.1-0.00.1-0.0-0.8-0.00.60.60.5-0.2-0.90.10.70.20.60.70.20.3
Bone: cortical apparent density1.01.53.7-1.9-1.9-1.31.6-1.0-1.51.4-1.11.21.3-1.41.00.81.0-1.4-1.70.80.51.10.31.01.00.6
Bone: cortical area2.64.212.63.52.62.7-1.91.11.9-1.81.3-1.4-0.92.4-2.2-2.0-2.22.42.7-1.9-1.5-2.2-1.3-1.3-1.9-1.5
Bone: cortical porosity2.42.65.21.5-0.41.80.8-0.9-0.50.5-0.90.81.91.6-2.1-2.3-2.01.71.7-1.8-2.2-1.8-2.2-1.7-1.7-1.7
Bone: cortical porosity1.92.14.41.90.11.70.3-0.40.0-0.0-0.40.31.51.6-2.0-2.1-1.91.61.6-1.6-1.9-1.7-1.9-1.4-1.5-1.4
Bone: cortical thickness2.74.513.53.72.02.9-1.40.71.5-1.40.7-0.7-0.22.7-2.6-2.4-2.62.72.8-2.1-2.0-2.4-1.8-1.3-2.1-1.7
Bone: cortical thickness0.50.62.61.61.01.1-0.80.61.0-1.00.8-0.9-0.20.6-0.8-0.8-0.80.71.1-0.4-0.6-0.6-0.5-0.4-0.4-0.3
Bone: cortical tissue density1.01.64.2-2.0-2.0-1.31.7-1.1-1.61.5-1.21.31.4-1.41.00.71.0-1.4-1.80.80.41.10.31.00.90.6
Condit. Reinf. active minus inactive responses0.91.13.01.71.70.6-1.71.51.7-1.71.5-1.6-1.20.4-0.3-0.2-0.30.40.60.00.1-0.20.20.30.00.3
Condit. Reinf. active-inactive response ratio0.60.61.91.21.10.0-1.21.31.4-1.41.3-1.3-0.80.00.00.00.10.00.10.30.30.20.40.60.40.6
Condit. Reinf. active responses1.51.95.92.32.41.0-2.21.92.2-2.11.9-2.0-1.70.9-0.6-0.3-0.60.90.9-0.20.1-0.60.20.3-0.30.1
Condit. Reinf. inactive responses0.30.41.31.01.20.5-1.00.81.0-0.90.8-0.9-0.70.4-0.3-0.2-0.30.50.4-0.2-0.0-0.40.10.1-0.3-0.1
Incentive salience index mean0.70.92.71.61.60.7-1.61.21.5-1.51.2-1.3-1.30.6-0.4-0.2-0.40.60.7-0.10.1-0.40.20.2-0.20.0
Condit. Reinf. lever presses0.20.30.8-0.10.5-0.4-0.70.60.5-0.50.4-0.5-0.9-0.30.50.60.4-0.2-0.20.60.70.30.70.60.30.4
Condit. Reinf. active minus inactive responses0.20.20.80.60.90.2-0.90.70.7-0.70.6-0.5-0.60.5-0.10.1-0.10.50.30.10.2-0.20.20.4-0.10.1
Condit. Reinf. active-inactive response ratio0.71.22.81.71.01.4-0.80.30.7-0.60.3-0.3-0.21.6-1.3-1.2-1.41.61.4-1.0-1.0-1.4-0.9-0.7-1.3-1.0
Condit. Reinf. active responses0.60.82.0-0.10.5-1.0-0.81.10.8-0.90.9-0.9-0.6-0.70.90.90.9-0.5-1.01.11.00.91.01.41.01.1
Condit. Reinf. inactive responses1.42.04.3-1.3-0.4-2.0-0.00.70.2-0.30.6-0.6-0.1-1.91.71.51.7-1.7-2.11.81.51.81.41.91.81.7
Condit. Reinf. lever presses1.72.54.0-0.11.1-1.7-1.41.91.6-1.71.8-1.8-1.0-1.31.41.41.5-1.4-1.61.81.61.61.62.01.81.9
Condit. Reinf. lever reinforcers received1.52.14.6-0.20.7-1.6-1.21.71.3-1.41.5-1.5-0.8-1.31.41.41.4-1.1-1.61.71.51.61.52.11.71.8
Conditioned reinforcement - actives0.00.10.9-0.10.2-0.9-0.30.50.1-0.10.10.0-0.3-0.00.30.40.30.0-0.30.50.40.20.40.40.10.3
Conditioned reinforcement - inactives0.20.51.31.11.10.7-0.91.00.8-0.81.0-0.9-0.70.8-0.4-0.3-0.40.80.60.1-0.1-0.3-0.1-0.1-0.4-0.1
Conditioned locomotion0.10.20.80.40.5-0.1-0.70.90.5-0.50.4-0.3-0.30.30.10.30.00.4-0.00.70.30.10.40.60.00.3
Patch foraging indifference point 0 sec0.10.31.20.30.5-0.3-0.50.90.7-0.80.6-0.6-0.3-0.30.20.10.2-0.3-0.80.40.30.40.31.10.50.6
Patch foraging indifference point AUC0.00.10.2-0.30.2-0.2-0.30.40.3-0.30.4-0.4-0.2-0.20.30.40.3-0.2-0.00.40.40.30.40.20.30.4
Delay disc. indifference point, 0s delay0.00.10.30.10.4-0.5-0.40.30.3-0.30.2-0.2-0.2-0.00.10.20.0-0.00.00.40.20.10.20.10.00.1
Delay disc. indifference point, 16s delay1.62.24.7-1.6-0.3-1.90.00.1-0.10.00.3-0.3-0.5-2.21.91.91.9-2.2-1.91.81.71.91.71.41.71.6
Delay disc. indifference point, 2s delay0.10.20.7-0.1-0.7-0.30.6-0.7-0.60.6-0.50.50.8-0.30.0-0.0-0.0-0.3-0.20.3-0.20.1-0.2-0.20.0-0.1
Delay disc. indifference point, 24s delay1.42.26.8-1.9-2.6-0.42.4-2.0-2.42.3-2.12.12.2-1.40.40.20.4-1.3-0.30.2-0.30.5-0.5-1.00.2-0.3
Delay disc. indifference point, 4s delay0.30.31.3-0.7-0.8-1.00.7-0.6-0.70.7-0.91.11.1-0.40.1-0.00.1-0.4-0.40.1-0.10.0-0.20.10.1-0.1
Delay disc. indifference point, 8s delay0.40.72.0-0.5-1.30.21.3-1.3-1.31.3-1.21.31.4-0.5-0.2-0.3-0.2-0.50.4-0.3-0.5-0.1-0.6-1.1-0.2-0.5
Indifference point function ln k0.20.72.0-1.1-0.8-1.40.60.0-0.40.4-0.20.30.2-1.11.00.81.0-1.1-1.40.70.71.00.60.90.90.8
Indifference point function log k0.20.72.0-1.1-0.8-1.40.60.0-0.40.4-0.20.30.2-1.11.00.81.0-1.1-1.40.70.71.00.60.90.90.8
Patch foraging total patch changes 0 sec0.20.72.30.30.6-0.6-0.81.31.0-1.10.9-0.9-0.4-0.60.50.40.5-0.7-1.10.80.60.70.61.50.91.0
Patch foraging total patch changes 12 sec0.00.00.2-0.10.10.10.00.10.1-0.20.0-0.00.40.2-0.3-0.4-0.30.3-0.1-0.1-0.3-0.2-0.30.3-0.1-0.0
Patch foraging total patch changes 18 sec0.82.04.1-1.00.6-1.7-0.81.20.9-1.01.2-1.2-1.0-1.51.51.41.5-1.5-1.81.61.51.61.52.01.71.7
Patch foraging total patch changes 24 sec0.20.82.60.91.40.5-1.41.41.5-1.51.5-1.6-1.00.1-0.00.1-0.00.20.40.60.30.20.40.40.30.5
Patch foraging total patch changes 6 sec0.30.51.10.60.31.1-0.30.10.3-0.20.1-0.10.30.9-1.0-0.9-1.00.90.8-0.7-0.8-0.9-0.8-0.4-0.8-0.7
Patch foraging time to switch 0 sec0.10.41.9-0.9-1.0-0.11.0-1.4-1.11.1-1.00.80.8-0.30.0-0.10.0-0.2-0.1-0.3-0.2-0.1-0.3-0.7-0.2-0.4
Patch foraging water rate 0 sec0.82.99.01.72.4-0.2-2.63.02.7-2.72.6-2.5-1.9-0.00.40.60.4-0.0-0.31.21.00.61.11.70.91.3
Patch foraging water rate 12 sec0.73.05.60.21.2-1.7-1.72.41.8-1.91.9-1.7-1.4-1.41.51.61.6-1.3-1.61.91.81.71.82.41.82.1
Patch foraging water rate 18 sec0.92.05.00.71.7-0.8-2.02.21.9-1.91.8-1.6-1.9-0.40.91.20.9-0.3-0.71.41.41.01.51.61.11.4
Patch foraging water rate 24 sec5.07.216.11.22.8-1.8-3.34.03.5-3.53.6-3.4-2.8-1.61.92.01.9-1.5-1.72.62.52.22.63.22.52.9
Patch foraging water rate 6 sec0.60.92.5-0.20.9-1.3-1.01.61.0-1.00.9-0.7-1.0-0.30.80.90.8-0.3-0.81.01.00.81.01.30.81.0
Seeking ratio, delayed vs. immediate footshock0.40.61.61.31.3-0.2-1.00.40.9-0.80.9-1.1-0.80.6-0.6-0.5-0.60.61.0-0.5-0.3-0.7-0.2-0.5-0.5-0.5
Distance traveled before self-admin0.20.51.61.30.90.3-0.90.91.1-1.20.9-1.0-0.40.4-0.7-0.7-0.60.40.8-0.2-0.5-0.4-0.4-0.1-0.2-0.0
Distance traveled after self-admin0.91.73.60.81.5-0.7-1.61.81.8-1.91.7-1.9-1.4-0.80.70.80.8-0.8-0.81.11.00.91.11.51.21.4
Extensor digitorum longus weight0.93.75.0-0.01.4-1.8-1.82.11.8-1.92.2-2.2-2.1-1.61.91.92.0-1.7-1.81.92.22.02.22.22.12.2
Bone: elastic displacement0.50.62.81.70.91.0-0.80.90.9-0.90.6-0.5-0.20.9-0.9-0.9-0.90.80.4-0.5-0.6-0.7-0.60.2-0.5-0.3
Bone: elastic work3.85.016.54.11.83.2-1.20.81.5-1.50.7-0.70.32.7-2.9-2.9-2.82.62.4-2.3-2.4-2.5-2.2-1.2-2.1-1.8
Bone: endosteal estimation0.30.81.3-0.60.6-1.0-0.70.70.6-0.71.0-1.1-1.0-1.01.11.11.1-1.0-0.61.01.21.01.20.41.01.0
Bone: endosteal perimeter0.41.02.31.21.11.3-0.6-0.00.5-0.40.3-0.4-0.31.1-1.1-1.0-1.11.11.5-1.2-0.8-1.2-0.8-1.5-1.1-1.0
Epididymis fat weight0.62.98.22.02.6-0.2-2.72.72.9-2.92.7-2.6-1.9-0.10.30.40.4-0.10.10.81.00.51.11.10.81.2
Delta time in closed arm before/after self-admin0.20.20.9-0.90.30.1-0.3-0.1-0.30.4-0.30.3-0.90.90.20.40.00.9-0.0-0.10.3-0.30.40.0-0.6-0.4
Delta time in open arm before/after self-admin0.30.30.80.20.3-0.7-0.40.60.6-0.60.6-0.5-0.3-0.90.40.50.4-0.8-0.10.80.40.60.50.30.70.6
Diff in mean of infusions in LGA sessions0.10.20.40.50.10.4-0.1-0.10.2-0.20.2-0.30.50.3-0.6-0.6-0.50.30.6-0.2-0.5-0.4-0.5-0.4-0.3-0.3
Delay discount exponential model param0.91.22.71.51.70.9-1.51.31.5-1.41.3-1.4-1.41.4-0.7-0.6-0.71.40.8-0.6-0.2-0.7-0.10.2-0.6-0.2
Extinction: sum of active levers before priming0.10.20.7-0.2-0.8-0.50.6-0.3-0.40.4-0.30.60.7-0.40.30.10.3-0.3-0.90.30.10.40.00.60.40.4
Active lever presses in extinction session 60.60.64.1-0.2-1.30.41.0-0.6-0.50.5-0.60.82.00.1-0.8-1.0-0.70.10.3-0.0-1.1-0.2-1.1-0.4-0.2-0.3
Bone: final force2.23.611.73.42.92.2-2.41.82.5-2.42.0-2.0-1.51.9-1.7-1.5-1.61.92.1-1.2-0.9-1.6-0.7-0.6-1.2-0.8
Bone: final moment2.64.214.43.83.02.5-2.51.92.6-2.52.1-2.1-1.42.1-2.0-1.8-1.92.02.3-1.4-1.2-1.8-1.0-0.7-1.4-0.9
Food consumed during 24 hour testing period0.20.51.40.80.80.6-1.01.11.2-1.21.0-0.9-0.30.10.00.10.10.0-0.30.60.30.20.31.10.40.6
Glucose5.07.924.4-2.0-4.7-0.24.6-4.1-4.14.0-4.04.04.9-0.2-1.2-1.8-1.1-0.3-0.0-1.4-2.4-0.7-2.7-1.7-0.9-1.7
Heart weight0.20.41.61.30.60.9-0.70.60.9-0.90.7-0.8-0.00.1-0.6-0.6-0.60.20.6-0.1-0.5-0.4-0.4-0.2-0.1-0.1
Delay discount hyperbolic model param0.81.12.51.31.60.8-1.51.31.4-1.31.2-1.4-1.51.3-0.6-0.5-0.61.30.8-0.5-0.1-0.7-0.00.2-0.6-0.2
Intermittent access intake day 1-15 change0.00.30.91.0-0.1-0.10.10.00.3-0.30.2-0.20.30.5-0.7-1.0-0.60.40.3-0.9-0.8-0.5-0.8-0.3-0.3-0.3
Intermittent access intake escalation0.00.20.80.9-0.1-0.10.1-0.00.2-0.20.1-0.20.20.5-0.6-0.9-0.50.40.3-0.9-0.7-0.4-0.7-0.2-0.3-0.2
Intermittent access intake escalation 20.50.82.51.20.10.4-0.00.10.5-0.40.3-0.40.31.2-1.3-1.6-1.21.10.8-1.4-1.2-1.0-1.2-0.6-0.8-0.7
Intermitt. access day 1 inactive lever presses0.22.26.01.62.41.0-2.32.22.4-2.52.3-2.3-1.7-0.30.20.40.3-0.20.21.00.80.50.91.00.71.0
Intermitt. access day 15 inactive lever presses0.31.74.21.11.9-0.7-1.92.01.8-1.81.9-1.8-1.9-0.10.60.70.6-0.0-0.51.11.00.71.11.30.61.1
Intermitt. access escalation Index0.20.51.70.81.30.4-1.21.01.0-1.01.0-1.0-1.2-0.10.30.50.2-0.20.30.50.60.20.70.20.20.3
Intermittent access day 1 total infusions0.00.10.10.30.2-0.4-0.30.40.3-0.30.3-0.2-0.30.00.00.10.00.1-0.00.10.10.00.10.30.10.1
Intermittent access day 15 total infusions0.10.20.90.90.5-0.2-0.50.40.6-0.60.6-0.6-0.50.5-0.4-0.4-0.40.40.5-0.3-0.3-0.3-0.2-0.1-0.2-0.1
Intermittent access terminal intake (last 3 days)0.20.41.11.10.6-0.3-0.60.60.7-0.70.6-0.6-0.50.8-0.7-0.7-0.60.80.7-0.5-0.5-0.6-0.4-0.3-0.5-0.3
Intermittent access total infusions0.10.10.70.80.4-0.6-0.40.50.5-0.50.5-0.4-0.40.2-0.2-0.1-0.10.10.3-0.1-0.0-0.1-0.00.1-0.00.0
Intermittent access day 1 locomotion0.00.10.30.20.30.5-0.40.50.2-0.20.2-0.1-0.30.4-0.10.1-0.10.50.10.10.1-0.10.10.1-0.2-0.0
Intermittent access day 15 total locomotion0.10.41.21.10.50.4-0.50.60.5-0.50.3-0.2-0.01.0-0.7-0.6-0.71.00.6-0.4-0.5-0.6-0.4-0.1-0.6-0.3
Intermittent access total locomotion0.10.10.40.60.40.2-0.50.60.4-0.40.4-0.3-0.30.7-0.3-0.3-0.30.70.3-0.1-0.2-0.3-0.10.1-0.3-0.1
Intermittent access standard deviation0.10.62.4-0.3-1.3-0.21.1-0.7-0.70.7-0.80.81.60.1-0.7-0.9-0.60.20.2-0.5-1.0-0.3-1.0-0.4-0.3-0.4
Left kidney weight0.21.21.90.5-0.41.20.5-1.0-0.60.6-0.91.00.91.4-1.4-1.3-1.41.31.3-1.1-1.3-1.3-1.3-1.3-1.4-1.3
Right kidney weight0.10.91.60.4-0.31.00.5-0.9-0.60.7-0.91.10.71.3-1.1-1.0-1.11.21.0-1.0-1.1-1.2-1.1-1.0-1.2-1.2
Cocaine induced anxiety0.71.95.02.20.21.90.0-0.10.3-0.30.2-0.30.81.4-1.9-2.0-1.81.42.1-1.2-1.9-1.4-1.8-1.6-1.2-1.2
Post-drug Anxiety0.70.93.11.0-0.91.11.0-0.6-0.50.4-0.50.51.80.3-1.1-1.4-1.00.30.8-0.6-1.4-0.6-1.4-0.9-0.4-0.6
Baseline Anxiety0.61.12.6-1.6-1.6-0.91.4-0.9-1.41.3-1.31.41.4-1.00.80.60.8-1.1-1.40.40.30.70.20.50.60.4
Tail length1.26.214.53.83.73.2-2.91.62.7-2.52.0-2.1-2.23.1-2.4-1.9-2.53.13.2-1.8-1.3-2.5-1.1-1.4-2.2-1.6
Length with tail1.77.615.83.42.33.7-1.30.21.1-0.90.3-0.5-0.24.0-3.4-3.1-3.53.84.0-2.8-2.7-3.5-2.5-2.8-3.3-2.8
Length without tail0.73.87.31.70.02.10.5-0.7-0.50.6-0.91.01.52.7-2.5-2.5-2.62.52.2-2.1-2.4-2.4-2.4-2.1-2.4-2.2
Times rat made contact with spout1.11.33.21.70.21.8-0.10.20.3-0.3-0.10.21.01.6-1.6-1.5-1.61.60.7-1.0-1.4-1.3-1.3-0.2-1.2-1.0
Lifetime Intake0.00.00.40.40.0-0.6-0.10.30.2-0.20.3-0.1-0.20.10.0-0.00.00.0-0.10.00.00.10.10.30.10.2
Liver weight, left0.50.92.1-0.7-1.20.61.3-1.4-1.31.3-1.31.31.10.3-0.6-0.6-0.60.30.4-0.6-0.8-0.6-0.9-1.0-0.7-0.9
Liver weight, right1.42.56.42.22.51.8-1.91.11.5-1.41.1-1.1-1.52.2-1.5-1.1-1.62.21.8-1.1-0.8-1.7-0.6-0.7-1.7-1.2
Locomotor activity0.30.42.1-1.4-0.9-1.10.7-0.5-0.70.6-0.60.50.7-0.60.50.40.5-0.6-0.80.60.20.50.20.50.40.3
Locomotor testing distance0.51.23.3-1.8-0.8-1.70.4-0.1-0.50.4-0.10.00.2-1.31.31.21.2-1.4-1.61.41.01.31.01.21.11.0
Locomotor testing rearing0.41.44.0-0.90.1-1.6-0.51.10.4-0.50.5-0.4-0.5-1.21.31.31.2-1.2-1.71.81.31.41.32.01.31.4
Locomotion in novel chamber0.20.20.8-0.10.5-0.0-0.50.50.2-0.10.3-0.1-0.8-0.10.50.80.4-0.0-0.20.90.60.40.70.40.20.3
Locomotion in novel chamber post-restriction0.51.44.32.11.41.8-1.00.81.1-1.00.8-0.6-1.01.4-1.2-1.1-1.21.41.5-1.5-0.8-1.3-0.7-0.9-1.0-0.8
Fecal boli incidents, locomotor time 10.10.21.0-1.0-0.4-0.70.3-0.4-0.50.5-0.20.20.1-0.20.40.50.4-0.2-0.30.30.30.30.30.30.20.1
Change in fecal boli incidents, locomotor task1.51.64.8-1.1-2.1-0.92.2-1.7-1.91.8-1.81.72.2-0.0-0.5-0.9-0.4-0.1-0.3-1.0-1.1-0.3-1.2-0.8-0.4-0.7
Time >=10cm from walls, locomotor time 10.50.71.6-0.20.8-1.0-0.81.20.8-0.80.6-0.4-1.2-0.20.80.80.8-0.2-1.10.11.00.51.01.20.60.8
Bouts of movement, locomotor time 10.60.82.2-1.4-1.5-0.41.4-1.3-1.21.2-1.01.01.0-1.10.60.40.6-1.0-0.40.20.10.60.0-0.40.60.2
Total resting periods, locomotor time 10.91.13.4-1.5-1.8-0.11.8-1.7-1.61.5-1.41.41.3-0.90.30.10.4-0.8-0.3-0.1-0.20.4-0.3-0.50.3-0.1
Rest time, locomotor task time 10.61.02.1-0.5-1.10.71.3-1.4-1.31.3-1.01.01.30.4-0.8-0.9-0.80.50.8-0.8-1.1-0.7-1.1-1.3-0.8-1.0
Distance moved, locomotor task time 10.10.31.10.61.0-0.0-1.00.90.9-0.80.7-0.7-0.80.10.10.20.00.10.10.20.4-0.00.40.30.10.2
Vertical activity count, locomotor time 10.21.33.50.91.7-0.0-1.81.91.7-1.61.5-1.4-1.6-0.00.50.70.5-0.1-0.80.61.00.41.11.40.50.9
Time >=10cm from walls, locomotor time 20.20.61.5-0.0-0.4-0.00.4-0.6-0.70.8-0.91.10.31.2-0.7-0.6-0.81.20.5-1.1-0.6-1.1-0.6-0.6-1.1-1.1
Bouts of movement, locomotor time 20.20.61.3-0.8-1.1-0.30.9-0.7-0.80.8-0.70.80.2-1.20.90.70.9-1.1-0.70.50.50.80.50.10.70.5
Total resting periods, locomotor time 20.10.40.8-0.6-0.6-0.20.4-0.4-0.50.5-0.40.5-0.3-0.90.90.80.9-0.9-0.60.50.70.80.70.20.60.5
Rest time, locomotor task time 20.20.30.8-0.1-0.30.90.6-0.5-0.70.7-0.60.70.30.6-0.3-0.3-0.30.60.3-0.6-0.4-0.5-0.4-0.6-0.5-0.6
Distance moved, locomotor task time 20.00.10.1-0.20.3-0.4-0.3-0.20.1-0.10.1-0.1-0.20.2-0.2-0.0-0.30.30.40.0-0.1-0.3-0.0-0.3-0.3-0.3
Vertical activity count, locomotor time 20.20.40.8-0.60.7-0.7-0.80.70.6-0.60.7-0.6-0.9-0.40.60.70.5-0.3-0.70.60.80.40.80.90.40.5
Light reinforcement 10.52.35.71.22.1-0.2-2.42.22.2-2.22.0-2.0-2.3-0.30.81.20.8-0.1-0.51.11.40.71.61.70.91.2
Light reinforcement 20.61.44.22.02.11.2-2.01.51.7-1.71.4-1.4-1.90.9-0.4-0.0-0.51.01.0-0.20.2-0.70.40.1-0.5-0.1
Bone: marrow area0.40.91.4-0.60.6-1.0-0.70.70.6-0.71.0-1.1-1.0-1.01.11.11.1-1.0-0.71.01.21.11.20.51.01.0
Bone: maximum diameter1.02.14.91.91.41.9-0.90.10.7-0.60.2-0.3-0.51.9-1.7-1.4-1.71.92.2-1.6-1.2-1.8-1.1-1.7-1.7-1.5
Bone: maximum force1.83.611.23.33.02.3-2.51.82.5-2.42.1-2.1-1.61.8-1.6-1.3-1.61.82.1-1.2-0.8-1.5-0.6-0.6-1.2-0.8
Bone: maximum moment2.24.113.53.73.12.5-2.51.82.6-2.52.1-2.2-1.42.0-1.9-1.6-1.82.02.2-1.4-1.0-1.7-0.8-0.7-1.3-0.9
Mean time between licks in bursts0.10.72.4-1.5-1.3-0.01.1-1.1-1.21.1-0.91.00.6-0.90.70.70.7-0.9-0.10.60.40.70.3-0.40.50.2
Mean num. licks in bursts0.10.20.80.8-0.20.40.10.10.3-0.40.2-0.30.90.2-0.6-0.7-0.50.3-0.4-0.0-0.6-0.2-0.60.7-0.10.0
Cd content in liver2.42.74.6-1.20.1-2.0-0.71.20.7-0.81.2-1.2-0.9-1.91.91.92.0-1.9-1.72.11.92.11.92.02.12.0
Co content in liver0.10.10.30.30.10.3-0.10.10.1-0.1-0.00.10.20.2-0.3-0.3-0.30.20.6-0.1-0.3-0.3-0.2-0.3-0.2-0.2
Cu content in liver0.91.02.21.50.31.1-0.00.10.2-0.2-0.10.20.71.4-1.4-1.5-1.41.41.1-1.2-1.3-1.3-1.3-0.7-1.1-1.0
Fe content in liver0.50.71.5-0.9-0.1-0.7-0.20.20.2-0.20.4-0.5-0.3-1.01.01.01.0-1.0-0.91.20.91.10.91.01.11.0
K content in liver1.01.03.70.91.70.4-1.81.41.5-1.41.3-1.3-1.90.40.20.50.10.40.00.40.7-0.00.80.80.00.3
Mg content in liver1.31.44.7-0.31.4-0.7-1.61.51.2-1.11.3-1.2-2.2-0.41.21.51.1-0.4-0.71.11.60.81.61.30.71.0
Mn content in liver0.10.10.50.20.30.3-0.20.1-0.00.1-0.20.3-0.10.7-0.4-0.3-0.40.7-0.0-0.4-0.2-0.5-0.20.2-0.6-0.4
Na content in liver0.10.20.9-0.00.6-0.0-0.50.30.3-0.30.3-0.4-1.0-0.10.40.60.3-0.1-0.10.30.50.20.60.50.20.2
Rb content in liver1.72.05.00.71.9-0.6-2.12.22.1-2.12.1-2.0-1.9-0.20.70.90.7-0.2-0.41.01.20.71.31.30.91.2
Se content in liver0.50.61.40.60.9-0.4-0.91.21.0-1.01.0-1.0-0.9-0.20.40.40.4-0.2-0.60.50.60.50.61.10.60.8
Sr content in liver0.80.72.10.3-1.00.51.1-1.0-0.90.9-1.01.01.50.4-0.8-1.0-0.80.40.4-0.8-1.1-0.6-1.1-0.7-0.6-0.8
Zn content in liver0.70.81.61.31.21.0-1.00.80.8-0.70.5-0.4-1.11.2-0.7-0.5-0.81.21.2-0.7-0.3-1.0-0.2-0.6-0.9-0.6
Bone: minimum diameter1.42.79.23.02.11.8-1.81.21.9-1.81.4-1.5-0.51.8-1.8-1.6-1.71.82.1-1.3-1.2-1.6-1.0-0.9-1.3-0.9
Time in familiar zone, hab. session 10.10.10.50.2-0.4-0.40.3-0.1-0.0-0.0-0.00.00.7-0.30.1-0.10.1-0.3-0.60.2-0.10.3-0.10.60.40.3
Time in novel zone, hab. session 10.00.10.6-0.20.3-0.0-0.30.20.2-0.10.2-0.1-0.80.10.10.20.10.10.10.10.20.00.30.1-0.00.0
Total zone transitions, hab. session 10.71.01.9-0.8-0.2-1.1-0.20.30.3-0.30.5-0.6-0.3-1.41.21.11.2-1.4-1.21.31.11.31.11.11.31.2
Total locomotion distance, hab. session 11.31.82.8-0.00.8-1.0-1.31.51.5-1.51.6-1.6-1.1-1.31.21.21.2-1.3-1.01.71.41.41.41.61.61.6
Locomotion velocity, hab. session 11.21.62.70.00.9-0.8-1.31.51.4-1.51.7-1.7-1.2-1.31.11.21.1-1.2-0.71.61.31.31.41.31.51.5
Time in familiar zone, hab. session 20.80.91.9-0.6-0.2-1.1-0.10.60.3-0.40.6-0.7-0.2-1.41.11.01.1-1.4-1.01.20.91.30.91.01.31.2
Time in novel zone, hab. session 20.20.20.6-0.2-0.20.30.4-0.6-0.60.6-0.70.80.10.6-0.4-0.3-0.40.70.1-0.6-0.4-0.6-0.4-0.3-0.7-0.6
Total zone transitions, hab. session 22.12.74.2-1.10.6-1.7-1.01.10.9-1.01.2-1.3-1.6-1.82.02.11.9-1.8-1.72.02.11.92.11.91.81.8
Total locomotion distance, hab. session 22.12.75.1-0.21.6-1.1-1.91.81.7-1.72.0-1.9-2.3-1.11.51.81.5-1.2-1.11.71.91.42.01.81.51.6
Locomotion velocity, hab. session 21.82.45.30.11.8-0.8-2.11.91.9-1.92.1-2.0-2.3-0.91.31.61.3-0.9-0.71.51.81.21.81.51.21.5
Novel to familiar place preference ratio0.81.15.22.31.00.7-0.81.11.2-1.20.9-0.80.51.3-1.2-1.4-1.11.20.3-0.8-0.9-0.9-0.90.5-0.6-0.2
Novelty place preference0.81.14.92.20.90.8-0.70.91.1-1.10.7-0.60.51.3-1.3-1.4-1.21.30.4-0.9-1.0-0.9-1.00.3-0.7-0.4
Time in novel zone, NPP test0.70.83.92.00.90.5-0.81.01.1-1.10.8-0.70.41.1-1.0-1.1-0.91.00.1-0.7-0.8-0.7-0.70.6-0.5-0.1
Total zone transitions, NPP test2.13.15.6-1.50.6-1.8-1.11.00.8-0.81.2-1.3-1.9-1.92.22.42.1-1.9-1.62.12.32.02.31.81.91.9
Total locomotion distance, NPP test2.94.06.6-0.81.5-1.7-1.92.01.7-1.82.1-2.1-2.6-1.72.22.42.1-1.9-1.22.32.52.02.61.92.02.2
Locomotion velocity, NPP test2.23.15.1-0.41.5-1.3-1.91.91.7-1.82.0-2.0-2.3-1.51.82.01.8-1.6-0.81.92.11.72.21.61.81.9
Intraocular pressure0.40.71.90.71.0-0.5-1.11.21.3-1.31.4-1.2-0.7-0.30.40.30.4-0.4-0.40.40.60.50.60.80.60.8
Delta distance traveled before/after self-admin1.01.12.1-0.70.2-1.2-0.40.80.5-0.50.6-0.6-0.6-1.21.21.31.2-1.2-1.41.41.21.21.21.41.31.3
Delta ambulatory time before/after self-admin0.81.33.0-1.3-0.4-1.60.10.3-0.20.10.00.1-0.2-1.41.51.51.4-1.4-1.71.41.41.41.31.41.31.2
Parametrial fat weight0.30.72.71.31.60.7-1.31.01.2-1.21.1-1.1-1.10.5-0.10.1-0.10.50.40.00.3-0.10.40.2-0.10.1
Pavlov. Cond. lever latency4.55.79.4-1.70.0-3.0-0.81.61.0-1.11.7-1.6-1.1-2.92.82.72.9-3.0-2.92.92.73.12.62.83.13.0
Pavlov. Cond. magazine entry latency2.12.76.22.40.72.5-0.3-0.10.4-0.3-0.20.00.51.8-2.1-2.0-2.11.92.4-1.7-1.9-1.9-1.8-1.9-1.7-1.6
Pavlov. Cond. change in total contacts0.91.02.21.2-0.41.00.6-0.5-0.30.3-0.70.61.40.9-1.3-1.5-1.31.00.9-1.1-1.4-1.1-1.4-0.9-0.9-0.9
Pavlov. Cond. index score3.24.08.52.61.22.9-0.5-0.10.5-0.3-0.30.10.12.5-2.5-2.3-2.62.62.9-2.2-2.1-2.6-2.0-2.2-2.4-2.2
Pavlov. Cond. latency score3.84.99.62.40.83.1-0.1-0.7-0.00.2-0.80.60.42.7-2.8-2.5-2.82.93.1-2.6-2.4-2.9-2.3-2.6-2.7-2.6
Pavlov. Cond. lever contacts2.22.75.01.40.32.20.2-0.8-0.40.5-0.90.80.42.0-2.0-1.8-2.02.22.2-1.9-1.8-2.2-1.7-1.9-2.1-2.0
Pavlov. Cond. magazine entry number2.93.77.5-2.6-0.4-2.7-0.20.5-0.10.00.6-0.4-1.2-2.12.62.62.5-2.2-2.52.22.42.32.32.32.12.0
Pavlov. Cond. intertrial magazine entries0.91.12.00.01.1-0.9-1.21.41.1-1.11.3-1.3-1.3-0.61.01.01.0-0.7-0.90.91.20.91.21.31.01.1
Pavlov. Cond. lever-magazine prob. diff.2.73.47.22.61.22.7-0.60.10.6-0.5-0.1-0.10.12.3-2.3-2.1-2.32.42.6-2.0-1.9-2.3-1.8-1.9-2.1-1.9
Pavlov. Cond. response bias2.93.67.12.30.32.70.2-0.6-0.10.2-0.80.70.92.2-2.5-2.4-2.42.32.5-2.2-2.3-2.3-2.2-2.3-2.2-2.1
Pavlov. Cond. lever latency2.12.95.8-0.5-1.81.22.1-2.4-2.22.2-2.42.41.81.0-1.3-1.4-1.31.10.8-1.8-1.7-1.4-1.8-1.6-1.6-1.8
Pavlov. Cond. magazine entry latency2.63.67.8-2.0-0.5-2.8-0.20.80.3-0.40.8-0.8-0.4-2.42.32.22.3-2.4-2.42.42.12.42.02.12.42.3
Pavlov. Cond. change in total contacts1.43.45.7-0.90.5-2.2-1.01.61.2-1.41.7-1.7-0.9-2.22.01.92.1-2.2-1.82.32.02.32.02.02.42.4
Pavlov. Cond. index score2.13.45.6-0.80.5-2.2-1.11.71.4-1.51.8-1.8-0.8-2.11.91.82.0-2.1-1.82.41.92.21.92.12.32.4
Pavlov. Cond. latency score2.03.35.5-0.80.6-2.1-1.21.71.4-1.51.8-1.8-1.0-2.01.91.92.0-2.0-1.72.32.02.22.02.02.22.3
Pavlov. Cond. lever contacts2.13.15.60.21.7-1.4-2.02.42.1-2.22.3-2.4-1.7-1.21.41.51.5-1.3-1.01.91.81.61.81.71.72.0
Pavlov. Cond. magazine entry number2.63.46.91.60.32.60.4-1.1-0.60.7-1.01.00.52.3-2.2-2.0-2.22.32.3-2.4-2.0-2.3-2.0-2.2-2.3-2.3
Pavlov. Cond. intertrial magazine entries0.40.82.51.51.61.0-1.41.11.2-1.21.0-1.0-1.10.8-0.5-0.3-0.50.90.5-0.3-0.1-0.60.00.3-0.5-0.2
Pavlov. Cond. lever-magazine prob. diff.2.23.45.8-1.00.3-2.3-0.91.51.2-1.31.6-1.6-0.6-2.22.01.92.0-2.3-1.92.41.92.31.92.12.42.4
Pavlov. Cond. response bias2.33.14.9-0.50.8-2.1-1.31.91.5-1.61.9-1.9-1.1-1.81.81.71.8-1.9-1.62.21.92.01.92.02.12.2
Time in closed arm before self-admin0.50.82.1-0.1-1.41.11.4-1.3-1.21.2-1.11.01.4-0.1-0.5-0.7-0.4-0.10.3-1.0-0.9-0.4-1.0-0.9-0.3-0.7
Time in closed arm after self-admin1.72.04.0-1.0-1.91.42.0-2.0-2.02.0-2.01.91.60.9-0.7-0.9-0.70.90.2-1.5-1.1-0.9-1.2-1.1-1.0-1.2
Time in open arm before self-admin0.20.31.2-0.30.90.0-0.80.40.2-0.10.2-0.1-1.01.10.00.3-0.11.10.20.10.3-0.40.40.1-0.7-0.3
Time in open arm after self-admin0.60.61.2-0.10.7-1.1-0.90.90.8-0.80.9-0.7-0.9-0.80.70.90.7-0.8-0.41.10.90.70.90.60.80.8
Bone: periosteal estimation0.61.33.81.91.91.2-1.51.01.5-1.41.3-1.4-1.11.1-0.9-0.8-0.91.11.4-0.7-0.4-0.9-0.3-0.7-0.7-0.5
Bone: periosteal perimeter3.26.311.93.01.43.4-0.5-0.60.4-0.2-0.30.20.53.1-3.2-3.0-3.23.23.4-3.0-2.7-3.2-2.6-2.9-3.0-2.8
Bone: post-yield work0.10.10.3-0.50.1-0.4-0.30.10.1-0.10.2-0.2-0.4-0.30.50.50.4-0.4-0.10.40.50.30.50.20.30.3
Progressive ratio test 1 active lever presses0.10.20.70.50.6-0.3-0.60.80.8-0.80.8-0.7-0.6-0.00.10.00.2-0.0-0.30.10.20.20.30.60.30.4
Progressive ratio test 1 breakpoint0.10.20.70.60.6-0.2-0.60.80.8-0.80.8-0.7-0.60.10.0-0.00.10.1-0.2-0.00.20.10.20.50.20.3
Progressive ratio test 1 inactive lever presses1.02.66.91.42.60.4-2.62.62.6-2.62.5-2.4-2.30.20.20.50.20.30.20.80.90.31.01.20.51.0
Progressive ratio test 2 active lever presses0.10.10.40.30.3-0.3-0.40.60.5-0.50.4-0.3-0.20.10.10.00.10.0-0.30.10.20.10.20.50.20.3
Progressive ratio test 2 breakpoint0.10.10.40.30.3-0.4-0.40.60.5-0.50.5-0.4-0.20.00.10.00.10.0-0.30.10.20.10.20.50.20.3
Progressive ratio test 2 inactive lever presses0.10.20.40.60.5-0.2-0.40.50.5-0.50.5-0.4-0.10.6-0.5-0.4-0.50.60.5-0.0-0.4-0.3-0.3-0.0-0.3-0.1
Incentive Sensitization - Responses0.00.00.1-0.10.30.2-0.30.20.3-0.30.3-0.2-0.20.1-0.0-0.00.00.0-0.1-0.00.1-0.00.10.20.00.1
Incentive Sensitization - Breakpoint0.00.00.1-0.10.30.1-0.20.20.3-0.30.2-0.2-0.10.1-0.0-0.0-0.00.0-0.10.00.0-0.00.10.20.10.1
Sum of active levers in priming session hrs 5-60.90.92.00.2-0.1-0.6-0.50.81.3-1.41.3-1.30.8-1.40.2-0.20.4-1.4-0.70.90.11.00.11.11.41.3
Progressive ratio0.10.41.8-1.1-0.9-1.30.8-0.5-0.80.8-0.70.70.5-0.60.50.40.5-0.7-0.70.50.20.50.10.20.40.3
Food seeking constrained by brief footshock0.20.31.40.5-0.8-0.50.8-0.4-0.50.5-0.50.51.20.1-0.4-0.6-0.30.1-0.2-0.2-0.6-0.1-0.6-0.0-0.0-0.1
Seeking ratio, punishment vs. effort0.10.10.50.70.40.3-0.50.40.5-0.50.6-0.7-0.3-0.20.20.20.2-0.2-0.10.10.30.20.30.30.30.3
Retroperitoneal fat weight1.87.922.14.14.70.7-4.54.54.7-4.64.3-4.2-3.30.6-0.00.30.00.60.61.01.10.21.41.60.71.5
Reaction time number correct2.59.013.9-1.12.2-2.8-2.83.32.6-2.73.0-2.8-3.6-2.73.23.53.2-2.5-2.43.43.73.13.73.23.13.4
Reaction time mean minus median0.21.01.40.1-0.81.01.0-1.1-1.01.1-1.11.00.91.0-0.9-0.9-0.91.10.7-1.2-1.1-1.0-1.1-1.1-1.1-1.2
Reaction time mean minus median AUC0.10.92.20.3-0.11.40.3-0.7-0.70.7-0.80.90.11.4-0.9-0.7-1.01.51.2-1.0-0.8-1.1-0.8-1.3-1.3-1.3
Reaction time num false alarms0.10.20.9-0.6-1.0-0.20.5-0.7-0.40.3-0.10.10.7-0.80.30.20.4-0.8-0.10.20.10.50.1-0.30.40.2
Reaction time num false alarms AUC0.20.41.2-1.0-1.1-0.50.7-0.9-0.60.6-0.30.40.6-0.90.50.40.5-0.9-0.30.30.30.60.2-0.20.50.3
Reaction time trials correct on left2.59.013.9-1.12.2-2.8-2.83.32.6-2.73.0-2.8-3.6-2.73.23.53.2-2.5-2.43.43.73.13.73.23.13.4
Reaction time trials on left2.79.214.2-1.12.2-2.8-2.83.42.6-2.73.0-2.9-3.7-2.73.23.53.2-2.5-2.43.43.73.13.83.23.13.4
Reaction time mean0.10.20.70.70.7-0.1-0.70.80.7-0.70.8-0.8-0.60.00.20.20.20.0-0.10.10.40.20.40.20.20.4
Reaction time mean AUC0.20.51.00.50.9-0.2-1.00.90.9-0.91.0-1.0-1.0-0.20.50.60.5-0.2-0.20.50.70.40.80.40.40.6
Median of all reaction times0.40.71.60.71.0-0.4-1.11.21.1-1.11.3-1.2-1.0-0.40.60.60.6-0.3-0.30.50.80.60.80.50.60.8
Reaction time omissions0.10.20.80.20.90.2-0.90.50.7-0.70.8-0.8-0.80.2-0.00.2-0.10.20.40.20.2-0.00.3-0.2-0.20.0
Reaction time false alarm rate1.62.35.9-0.4-2.10.92.0-2.4-1.81.8-1.81.72.30.5-1.1-1.3-1.00.40.8-1.4-1.6-1.0-1.6-1.7-1.1-1.4
Reaction time premature initiation rate0.60.92.4-1.3-1.5-0.81.2-0.6-1.01.0-0.60.41.4-1.40.80.60.9-1.4-1.20.80.41.00.30.40.90.6
Reaction time premature initiations1.34.07.3-1.7-0.2-2.3-0.41.30.5-0.61.1-1.2-0.7-2.72.52.42.5-2.6-2.52.52.32.62.32.22.52.4
Std. dev. reaction times0.00.10.4-0.6-0.6-0.40.4-0.4-0.50.5-0.20.20.2-0.30.40.40.4-0.3-0.40.10.30.40.2-0.10.20.2
Reaction time trials completed2.79.214.2-1.12.2-2.8-2.83.42.6-2.73.0-2.9-3.7-2.73.23.53.2-2.5-2.43.43.73.13.83.23.13.4
Reaction time trials AUC2.79.314.3-1.02.3-2.8-2.93.42.7-2.73.1-2.9-3.7-2.73.23.53.2-2.5-2.53.43.73.13.83.33.13.4
Run reversals in cocaine runway, females1.71.95.1-1.2-0.7-1.80.10.20.1-0.20.3-0.4-0.2-2.31.71.61.8-2.3-1.61.41.51.71.41.21.91.6
Run reversals in cocaine runway, males1.21.32.81.30.50.9-0.1-0.10.2-0.20.10.10.31.7-1.5-1.6-1.51.61.4-1.5-1.4-1.4-1.3-1.1-1.3-1.2
Latency to leave start box in cocaine runway0.20.30.7-0.4-0.5-0.80.4-0.3-0.40.3-0.40.50.0-0.90.70.70.7-0.9-0.70.50.50.60.50.40.60.5
Latency to leave start box in cocaine runway, F0.81.02.2-0.80.2-1.1-0.60.40.3-0.30.4-0.4-0.9-1.21.31.51.2-1.2-1.01.41.41.11.41.01.01.1
Latency to leave start box in cocaine runway, M0.30.30.70.3-0.8-0.00.9-0.6-0.60.6-0.70.80.80.0-0.3-0.5-0.20.0-0.1-0.6-0.5-0.2-0.6-0.2-0.1-0.3
Std. dev. time between licks in bursts1.83.46.9-0.31.90.2-2.21.91.9-1.92.1-2.1-2.6-1.41.92.21.9-1.3-0.52.02.41.82.41.61.81.9
Total sessions with >9 infusions0.10.10.9-0.4-0.4-0.90.40.0-0.40.4-0.20.4-0.20.00.30.20.30.1-0.80.10.20.30.20.60.20.3
Short access day 1 total inactive lever presses0.10.10.40.00.60.6-0.60.20.3-0.20.4-0.5-0.50.20.10.40.00.10.40.50.3-0.00.4-0.1-0.2-0.1
Short access day 10 total inactive lever presses0.21.75.31.92.31.5-2.11.92.1-2.01.8-1.8-1.50.7-0.5-0.2-0.50.71.00.20.1-0.40.30.2-0.20.2
Short access day 1 total infusions0.40.82.1-1.1-1.2-1.21.0-0.5-0.90.9-0.70.90.4-1.00.90.70.9-0.9-1.40.60.60.90.50.80.70.6
Short access day 10 total infusions0.30.51.51.20.70.9-0.70.90.9-0.90.8-0.7-0.40.8-0.7-0.7-0.70.80.8-0.4-0.5-0.5-0.4-0.1-0.4-0.2
Short access total infusions0.10.20.70.2-0.1-0.6-0.10.50.3-0.30.4-0.2-0.2-0.40.40.30.4-0.4-0.70.40.30.50.30.90.50.6
Short access day 1 locomotion0.10.20.8-0.1-0.8-0.20.9-0.4-0.70.7-0.70.90.60.1-0.2-0.3-0.20.2-0.1-0.5-0.4-0.2-0.5-0.3-0.2-0.3
Short access day 10 total locomotion0.31.21.90.0-0.80.91.0-0.8-0.90.9-1.01.11.11.2-1.2-1.3-1.11.30.8-1.2-1.3-1.1-1.4-1.0-1.2-1.1
Short access total locomotion0.50.71.50.4-0.50.50.7-0.5-0.70.7-0.70.90.71.1-0.9-1.1-0.91.20.6-1.1-1.0-0.9-1.1-0.7-1.0-0.9
One hour access (0.3 mA shock)0.30.41.20.40.3-0.8-0.60.90.7-0.80.7-0.6-0.6-0.30.50.40.5-0.4-0.90.30.60.50.61.10.60.8
Compulsive drug intake0.71.02.50.31.60.5-1.41.01.3-1.31.4-1.5-1.6-0.50.70.80.7-0.6-0.30.71.00.61.10.70.70.8
One hour access (shock baseline)0.00.10.40.4-0.2-0.3-0.00.1-0.10.2-0.20.3-0.00.6-0.2-0.2-0.30.60.3-0.3-0.2-0.4-0.2-0.2-0.4-0.3
Social response proportion0.40.51.1-0.80.1-1.1-0.20.60.1-0.20.3-0.3-0.3-0.70.90.90.8-0.6-0.61.00.80.90.80.70.80.8
Social responses0.10.20.4-0.30.4-0.6-0.30.60.2-0.20.2-0.0-0.5-0.30.40.50.4-0.2-0.20.50.50.30.50.40.30.4
Social time0.20.31.5-0.40.1-1.2-0.20.50.2-0.20.2-0.1-0.2-0.60.60.60.6-0.5-0.70.60.60.50.60.70.60.7
Soleus weight0.72.14.62.21.92.1-1.50.71.2-1.10.8-0.9-1.41.7-1.4-1.1-1.51.72.1-1.2-0.8-1.6-0.7-1.3-1.5-1.2
Bone: stiffness0.20.41.30.81.10.7-0.90.40.7-0.70.7-0.8-0.70.5-0.3-0.2-0.40.50.9-0.5-0.1-0.5-0.0-0.5-0.4-0.3
Tibialis anterior weight0.00.10.7-0.10.5-0.4-0.30.10.1-0.10.3-0.3-0.8-0.10.40.40.4-0.2-0.2-0.00.50.20.5-0.10.10.2
Time to tail flick, vehicle, before self-admin0.30.40.9-0.5-0.70.80.6-0.9-0.80.9-0.70.90.40.3-0.3-0.2-0.30.40.5-0.4-0.4-0.4-0.4-0.8-0.6-0.7
Time to tail flick, vehicle, after self-admin0.51.03.2-1.4-1.40.61.3-1.6-1.81.8-1.61.50.80.20.00.1-0.10.20.2-0.2-0.3-0.3-0.3-0.9-0.7-0.8
Time to tail flick, test, before self-admin0.30.41.3-0.1-0.90.30.9-1.1-0.90.9-0.80.80.70.3-0.3-0.4-0.30.30.2-0.6-0.6-0.3-0.6-0.6-0.5-0.6
Time to tail flick, test, after self-admin1.01.02.2-0.8-1.30.11.4-1.2-1.41.5-1.41.51.40.8-0.6-0.7-0.70.80.2-0.6-0.9-0.6-1.0-0.7-0.9-0.9
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.00.7-0.3-0.60.70.4-0.40.3-0.5-0.7-0.10.40.60.3-0.1-0.20.70.60.40.60.50.20.4
Delta time to tail flick, test, before/after SA0.30.31.1-0.5-0.8-0.70.9-0.5-0.80.8-0.80.91.10.3-0.3-0.5-0.30.3-0.2-0.4-0.5-0.2-0.6-0.2-0.3-0.3
Tibia length5.214.437.36.13.85.4-2.61.12.6-2.31.3-1.3-0.94.9-4.6-4.2-4.64.74.9-4.0-3.4-4.5-3.1-3.0-4.1-3.4
Ambulatory time before self-admin0.41.34.02.01.60.7-1.61.61.9-1.91.5-1.6-0.90.5-0.8-0.8-0.70.61.0-0.2-0.4-0.4-0.30.0-0.10.1
Ambulatory time after self-admin0.91.43.00.61.2-0.8-1.41.71.7-1.71.5-1.6-1.1-0.70.60.70.7-0.7-0.81.10.90.91.01.51.11.3
Bone: tissue strength0.91.02.91.41.70.5-1.71.61.6-1.61.4-1.4-1.30.6-0.2-0.0-0.20.60.40.10.3-0.30.40.6-0.10.2
Total heroin consumption0.10.10.70.4-0.0-0.2-0.20.10.5-0.60.5-0.50.80.2-0.4-0.5-0.40.20.00.3-0.4-0.0-0.40.40.10.2
Bone: trabecular number0.10.20.60.10.10.40.3-0.6-0.40.4-0.50.40.00.5-0.4-0.4-0.40.40.1-0.8-0.4-0.5-0.4-0.6-0.6-0.6
Bone: trabecular spacing3.95.68.2-0.61.5-2.2-2.32.92.3-2.42.7-2.7-2.5-1.92.32.42.3-1.9-1.82.82.72.42.72.82.52.7
Bone: trabecular thickness1.92.64.51.6-0.31.90.8-1.3-0.60.7-1.00.91.51.7-2.0-2.1-1.91.71.7-2.0-2.0-1.9-2.0-1.8-1.8-1.8
Bone: trabecular tissue density0.20.41.7-1.3-1.0-0.20.8-0.8-1.01.0-0.70.70.5-0.70.50.50.4-0.5-0.30.40.20.40.2-0.10.2-0.0
Water consumed over 24 hours0.51.01.60.3-0.80.70.9-1.0-0.80.9-1.11.21.31.2-1.2-1.2-1.21.10.3-1.0-1.2-1.1-1.3-0.3-1.1-1.1
Number of responses in last shaping day0.10.20.80.20.50.7-0.20.3-0.00.10.10.0-0.30.7-0.3-0.2-0.40.90.6-0.1-0.2-0.4-0.2-0.4-0.6-0.4