Hub : Genes

Tent4b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Tent4b 0.04 0.03 3.0e-03 0.01 0.03 0.03 0.03 5.1e-02 1.3e-03 2.3e-03 2.0e-03
2 PL gene expression Tent4b 0.04 0.03 1.5e-04 0.03 0.03 0.02 0.03 2.5e-04 3.1e-04 4.4e-03 7.8e-04
3 PL alternative TSS NM_001107416.2 0.12 0.09 2.6e-03 0.02 0.02 0.04 0.03 1.5e-03 2.7e-03 7.3e-05 1.8e-04
4 Adipose alternative TSS XM_063278017.1 0.05 0.04 8.2e-04 0.03 0.01 0.02 0.02 4.9e-04 1.0e-02 2.1e-03 3.3e-03
5 Adipose isoform ratio XM_063278017.1 0.06 0.04 9.6e-04 0.03 0.02 0.02 0.02 4.4e-04 5.1e-03 1.2e-03 1.9e-03
6 Adipose alternative TSS XM_063278017.1 0.06 0.05 1.5e-03 0.02 0.01 0.02 0.02 1.6e-03 1.3e-02 4.0e-03 5.0e-03
7 Brain mRNA stability Tent4b 0.06 0.04 8.5e-04 0.03 0.03 0.01 0.03 6.1e-04 1.1e-03 1.4e-02 5.5e-04
8 PL isoform ratio XM_063278017.1 0.06 0.04 9.2e-03 0 0.01 0.02 0.01 8.1e-02 5.8e-02 3.9e-03 2.5e-02
9 PL alternative TSS XM_063278017.1 0.06 0.05 7.4e-03 0 0 0.01 0.01 8.4e-02 7.9e-02 1.3e-02 5.7e-02
10 PL mRNA stability Tent4b 0.05 0.04 3.7e-03 -0 -0 -0 -0 6.3e-01 7.0e-01 8.1e-01 8.5e-01
11 BLA mRNA stability Tent4b 0.14 0.09 1.8e-03 0.01 0.02 -0 0 8.4e-02 4.1e-02 4.9e-01 3.4e-01
12 LHb alternative TSS XM_039097723.2 0.16 0.11 5.9e-03 0.01 0.06 0.06 0 1.4e-01 1.9e-02 1.8e-02 2.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.91.63.81.9-1.8-1.61.31.31.20.71.01.0-0.91.0-0.2
Area under the delay curve0.10.20.5-0.60.7-0.2-0.5-0.5-0.5-0.50.10.20.7-0.30.4
BMI with tail1.65.511.8-2.22.92.4-3.4-3.4-3.00.4-2.4-2.2-0.3-0.41.8
BMI without tail0.10.41.0-0.30.60.5-0.8-0.8-0.80.5-0.5-0.5-1.00.2-0.3
Body weight0.62.78.7-0.81.22.9-1.7-1.7-1.51.2-2.4-2.3-1.00.30.1
Weight adjusted by age1.23.47.0-1.32.11.7-2.6-2.6-2.30.4-1.9-1.8-0.0-0.02.2
Bone surface0.61.13.31.8-1.6-0.10.80.80.71.5-0.2-0.3-1.51.1-0.1
Bone volume1.22.37.02.6-2.3-0.31.41.41.31.80.0-0.1-1.81.7-0.7
Breakpoint value in progressive ratio session0.71.32.4-0.2-0.7-1.41.31.31.3-1.11.51.51.1-1.0-0.4
Number of licking bursts0.20.61.20.1-0.6-0.71.01.00.9-0.60.90.90.4-0.3-1.1
Context. condit. distance diff. score3.23.910.3-3.22.3-0.5-1.0-1.0-0.8-2.50.70.82.6-3.02.3
Locomotion velocity, session 10.50.62.40.9-1.00.20.80.80.90.40.10.1-0.40.7-1.6
Locomotion distance, session 10.60.81.6-0.70.1-0.90.70.70.7-1.31.11.11.0-1.0-0.6
Locomotion velocity, session 20.10.20.3-0.2-0.1-0.40.50.50.6-0.20.50.50.3-0.5-0.2
Locomotion distance, session 20.40.61.5-1.10.6-0.50.10.10.2-1.20.60.61.2-1.10.5
Locomotion velocity, session 31.51.73.0-1.11.61.4-1.7-1.7-1.60.1-1.4-1.30.4-0.21.5
Locomotion distance, session 30.20.20.6-0.60.70.4-0.4-0.4-0.4-0.6-0.2-0.20.8-0.30.2
Stereotopy head waving bouts, day 30.60.71.9-0.90.70.9-1.1-1.1-0.9-0.1-0.8-0.70.5-0.61.4
Stereotopy head waving duration, day 30.60.81.8-1.10.90.5-1.2-1.2-1.0-0.3-0.5-0.50.6-0.71.4
Locomotion velocity, session 72.22.45.2-1.81.1-1.8-0.1-0.1-0.1-2.31.61.72.1-2.01.5
Locomotion distance, session 72.32.97.2-0.7-0.4-2.71.11.11.0-2.22.42.42.0-1.60.7
Stereotopy head waving bouts, day 71.51.85.5-0.50.82.3-1.5-1.5-1.40.8-1.9-1.9-0.50.40.4
Stereotopy head waving duration, day 71.31.65.70.7-0.42.4-0.6-0.6-0.51.5-1.8-1.9-1.11.2-0.6
Locomotion velocity, session 82.53.07.1-2.00.9-1.70.10.10.3-2.61.61.72.7-2.41.8
Locomotion distance, session 82.73.99.7-2.91.6-1.2-0.1-0.10.1-3.01.51.63.0-3.11.6
Degree of sensitization distance1.41.54.8-0.3-0.6-2.20.80.80.8-1.21.81.91.0-1.10.9
Degree of sensitization stereotypy1.21.33.2-0.30.81.8-1.3-1.3-1.30.8-1.6-1.6-0.70.60.0
Conditioned locomotion0.10.10.30.3-0.3-0.30.30.30.10.30.20.1-0.40.3-0.5
Cocaine response after cond. corrected1.31.94.1-1.91.3-1.6-0.5-0.5-0.5-2.01.31.41.7-1.60.6
Cocaine response after cond. not corrected0.50.71.9-1.40.9-0.7-0.6-0.6-0.6-1.20.50.61.1-0.90.2
Cocaine response before conditioning2.12.55.01.9-1.62.10.70.70.72.2-1.6-1.7-1.61.7-1.5
Saline control response3.54.88.9-0.0-1.4-2.92.72.72.4-1.93.02.91.6-1.7-0.6
Bone: connectivity density0.91.44.41.3-1.5-2.11.21.21.10.11.41.4-0.30.20.5
Bone: cortical apparent density0.60.92.0-0.80.6-1.4-0.2-0.2-0.2-1.21.01.11.1-0.81.4
Bone: cortical area0.20.30.80.7-0.50.9-0.0-0.00.20.8-0.7-0.7-0.80.40.2
Bone: cortical porosity0.40.42.0-0.10.21.4-0.5-0.5-0.40.3-1.0-1.0-0.10.3-0.0
Bone: cortical porosity0.20.31.40.2-0.21.2-0.1-0.1-0.10.3-0.7-0.8-0.30.3-0.3
Bone: cortical thickness0.20.40.80.40.10.8-0.7-0.7-0.50.6-0.8-0.8-0.90.50.4
Bone: cortical thickness0.40.51.1-0.60.4-1.10.00.00.1-0.70.90.90.7-0.90.9
Bone: cortical tissue density0.71.02.2-0.90.7-1.5-0.3-0.3-0.2-1.31.11.21.2-0.91.5
Condit. Reinf. active minus inactive responses0.70.72.4-1.61.10.2-0.6-0.6-0.5-1.00.00.11.1-1.20.6
Condit. Reinf. active-inactive response ratio0.91.03.8-1.91.30.5-0.6-0.6-0.4-1.0-0.1-0.01.2-1.60.6
Condit. Reinf. active responses0.00.00.10.0-0.00.30.00.0-0.0-0.0-0.1-0.10.00.0-0.2
Condit. Reinf. inactive responses1.72.27.12.7-2.2-0.61.41.41.21.10.50.3-1.51.9-1.2
Incentive salience index mean0.20.30.6-0.1-0.4-0.10.70.70.7-0.50.50.50.5-0.4-0.7
Condit. Reinf. lever presses1.01.53.31.4-1.5-0.51.71.71.60.20.80.7-0.40.6-1.8
Condit. Reinf. active minus inactive responses0.10.20.4-0.40.40.6-0.6-0.6-0.4-0.1-0.5-0.50.2-0.00.5
Condit. Reinf. active-inactive response ratio0.81.32.30.60.51.3-1.1-1.1-1.11.4-1.5-1.5-1.21.4-0.1
Condit. Reinf. active responses0.10.20.7-0.40.10.6-0.4-0.4-0.1-0.3-0.3-0.20.5-0.30.8
Condit. Reinf. inactive responses0.60.82.2-1.20.2-0.2-0.1-0.10.3-1.30.60.71.4-1.51.3
Condit. Reinf. lever presses0.40.61.2-0.90.70.7-1.0-1.0-0.7-0.4-0.5-0.40.4-0.61.1
Condit. Reinf. lever reinforcers received0.30.41.0-0.50.41.0-0.9-0.9-0.5-0.1-0.8-0.70.3-0.20.9
Conditioned reinforcement - actives0.00.10.5-0.4-0.10.30.20.20.5-0.40.10.20.3-0.70.2
Conditioned reinforcement - inactives0.20.52.0-1.20.31.4-0.4-0.4-0.1-0.4-0.7-0.70.2-1.20.1
Conditioned locomotion0.10.10.30.0-0.2-0.60.30.30.4-0.30.40.50.1-0.30.3
Patch foraging indifference point 0 sec0.41.12.9-1.61.2-0.1-0.4-0.4-0.4-1.30.30.31.7-1.51.4
Patch foraging indifference point AUC0.30.81.61.1-1.2-0.61.11.11.30.00.70.7-0.20.5-0.8
Delay disc. indifference point, 0s delay0.50.61.40.9-1.20.51.01.01.00.40.0-0.0-0.10.5-1.2
Delay disc. indifference point, 16s delay0.40.61.5-0.61.00.3-1.2-1.2-1.0-0.2-0.4-0.30.1-0.10.9
Delay disc. indifference point, 2s delay0.40.41.40.10.7-0.2-1.0-1.0-1.20.3-0.3-0.3-0.60.70.2
Delay disc. indifference point, 24s delay0.00.00.1-0.00.00.00.00.0-0.1-0.10.10.00.10.0-0.4
Delay disc. indifference point, 4s delay1.21.22.9-0.70.3-1.70.20.20.3-1.61.61.61.5-1.00.5
Delay disc. indifference point, 8s delay0.30.61.4-1.21.10.6-0.8-0.8-0.7-0.6-0.3-0.31.0-0.60.4
Indifference point function ln k0.30.82.4-1.31.50.1-1.1-1.1-1.3-0.3-0.4-0.40.3-0.61.0
Indifference point function log k0.30.82.4-1.31.50.1-1.1-1.1-1.3-0.3-0.4-0.40.3-0.61.0
Patch foraging total patch changes 0 sec0.41.33.0-1.71.30.0-0.6-0.6-0.5-1.30.20.21.7-1.61.5
Patch foraging total patch changes 12 sec1.31.72.8-0.4-0.7-1.11.51.51.6-1.41.51.51.7-1.4-0.0
Patch foraging total patch changes 18 sec0.61.53.30.4-1.4-1.11.61.61.8-0.71.41.41.0-0.80.1
Patch foraging total patch changes 24 sec0.41.42.7-0.1-0.8-0.81.41.41.6-1.31.31.31.5-1.10.1
Patch foraging total patch changes 6 sec0.30.50.9-0.2-0.2-0.50.90.90.9-0.80.80.70.8-0.7-0.1
Patch foraging time to switch 0 sec0.00.21.1-0.4-0.11.00.00.00.10.2-0.6-0.60.2-0.40.2
Patch foraging water rate 0 sec0.10.31.00.6-0.2-1.00.10.1-0.0-0.20.60.6-0.30.7-0.6
Patch foraging water rate 12 sec0.10.41.21.1-0.9-0.50.50.50.50.60.30.3-0.90.8-0.7
Patch foraging water rate 18 sec1.43.17.52.7-1.80.41.11.10.82.0-0.4-0.6-2.42.6-2.5
Patch foraging water rate 24 sec0.10.10.40.5-0.2-0.40.10.1-0.10.20.10.1-0.50.6-0.6
Patch foraging water rate 6 sec2.33.46.02.2-2.5-2.12.32.32.00.11.91.7-0.70.8-1.6
Seeking ratio, delayed vs. immediate footshock1.82.67.2-2.52.70.5-1.8-1.8-1.9-1.1-0.6-0.50.9-1.41.7
Distance traveled before self-admin0.92.14.1-1.01.71.7-1.8-1.8-2.00.7-1.8-1.8-0.50.30.4
Distance traveled after self-admin1.42.54.90.90.22.1-0.9-0.9-1.02.2-2.1-2.2-2.01.8-0.7
Extensor digitorum longus weight0.72.86.91.4-0.21.9-0.7-0.7-0.82.4-2.0-2.1-2.62.0-0.7
Bone: elastic displacement0.20.30.8-0.20.2-0.90.10.10.1-0.90.70.80.5-0.30.4
Bone: elastic work0.00.00.20.3-0.1-0.0-0.3-0.3-0.10.0-0.1-0.0-0.20.40.2
Bone: endosteal estimation0.00.10.4-0.30.2-0.10.30.30.4-0.20.20.20.6-0.40.0
Bone: endosteal perimeter0.20.51.6-0.90.4-0.30.30.30.5-0.80.50.51.1-1.30.7
Epididymis fat weight0.10.51.0-1.00.81.0-0.7-0.7-0.5-0.4-0.7-0.60.4-0.50.2
Delta time in closed arm before/after self-admin0.20.20.4-0.70.6-0.0-0.5-0.5-0.5-0.4-0.00.00.2-0.40.2
Delta time in open arm before/after self-admin0.50.61.20.8-0.9-0.91.11.10.9-0.00.90.80.10.2-0.5
Diff in mean of infusions in LGA sessions1.32.44.6-1.20.2-2.20.70.70.8-2.01.92.02.0-2.01.0
Delay discount exponential model param0.20.20.50.5-0.60.40.50.50.50.6-0.3-0.4-0.70.3-0.4
Extinction: sum of active levers before priming1.52.35.1-1.92.20.1-2.3-2.3-2.1-0.8-0.5-0.40.6-0.81.6
Active lever presses in extinction session 60.20.20.60.30.1-0.4-0.3-0.3-0.60.30.0-0.0-0.80.6-0.5
Bone: final force1.52.54.92.2-1.71.90.30.30.62.2-1.5-1.5-1.82.0-1.1
Bone: final moment1.32.14.21.8-1.32.00.00.00.32.0-1.6-1.6-1.71.7-0.8
Food consumed during 24 hour testing period1.63.28.12.1-2.8-0.82.62.62.80.31.31.20.30.3-1.1
Glucose0.30.41.80.9-1.40.40.70.70.80.5-0.1-0.1-0.20.4-0.5
Heart weight0.71.22.4-1.61.2-0.8-0.7-0.7-0.6-1.30.60.61.2-1.51.5
Delay discount hyperbolic model param0.20.30.60.6-0.60.50.40.40.40.7-0.4-0.4-0.80.3-0.4
Intermittent access intake day 1-15 change0.63.57.81.9-2.6-0.12.72.72.80.40.80.7-1.00.4-2.6
Intermittent access intake escalation0.52.86.41.7-2.3-0.22.42.42.40.40.80.7-1.20.4-2.5
Intermittent access intake escalation 21.42.45.70.9-2.0-0.32.42.42.4-0.51.11.0-0.3-0.5-2.0
Intermitt. access day 1 inactive lever presses0.00.41.4-0.80.10.7-0.4-0.4-0.1-0.2-0.2-0.21.2-0.91.0
Intermitt. access day 15 inactive lever presses0.21.02.7-1.61.0-0.0-0.6-0.6-0.6-1.10.10.11.1-1.51.3
Intermitt. access escalation Index0.10.52.0-0.30.5-1.4-0.3-0.3-0.5-1.00.90.90.3-0.20.0
Intermittent access day 1 total infusions0.51.43.0-1.31.61.0-1.7-1.7-1.6-0.2-1.0-1.00.0-0.41.0
Intermittent access day 15 total infusions0.10.21.20.10.10.6-0.1-0.1-0.00.3-0.5-0.5-1.10.2-0.7
Intermittent access terminal intake (last 3 days)0.10.10.3-0.60.50.2-0.1-0.1-0.0-0.4-0.1-0.0-0.1-0.60.1
Intermittent access total infusions0.10.10.3-0.20.20.5-0.2-0.2-0.0-0.1-0.4-0.3-0.3-0.1-0.1
Intermittent access day 1 locomotion0.30.61.10.50.40.5-0.9-0.9-0.71.0-0.8-0.8-0.91.00.3
Intermittent access day 15 total locomotion0.31.12.10.60.41.3-0.8-0.8-0.71.4-1.4-1.4-1.31.3-0.3
Intermittent access total locomotion0.70.92.10.40.31.4-0.6-0.6-0.51.1-1.3-1.3-1.21.0-0.6
Intermittent access standard deviation0.21.02.80.7-1.3-0.31.51.51.7-0.30.70.7-0.0-0.2-1.1
Left kidney weight0.32.14.52.1-2.00.61.41.41.41.5-0.2-0.3-1.41.5-2.1
Right kidney weight0.10.82.80.7-1.01.30.80.80.70.7-0.5-0.7-0.50.5-1.7
Cocaine induced anxiety0.61.75.1-2.10.9-0.70.00.00.1-2.21.01.11.6-2.30.8
Post-drug Anxiety0.80.92.8-1.50.7-0.9-0.0-0.0-0.0-1.70.91.00.9-1.50.4
Baseline Anxiety0.40.72.01.3-0.6-0.10.20.2-0.11.2-0.3-0.4-1.31.4-1.0
Tail length0.52.75.52.2-2.3-0.82.12.11.90.80.90.7-1.21.0-2.0
Length with tail0.31.12.21.1-1.21.50.70.70.71.3-0.9-1.0-1.00.9-1.3
Length without tail0.31.77.5-0.50.62.7-1.0-1.0-0.71.0-2.0-2.0-0.20.10.4
Times rat made contact with spout0.40.51.20.8-0.40.7-0.4-0.4-0.31.1-0.8-0.8-0.70.80.4
Lifetime Intake0.10.10.2-0.40.00.30.10.10.3-0.4-0.0-0.00.1-0.5-0.2
Liver weight, left0.10.20.60.0-0.60.50.70.70.80.00.00.00.2-0.4-0.6
Liver weight, right0.40.83.30.3-0.01.8-0.5-0.5-0.30.9-1.2-1.3-0.60.7-0.8
Locomotor activity0.20.30.70.10.20.5-0.8-0.8-0.80.4-0.6-0.6-0.70.50.0
Locomotor testing distance0.00.10.4-0.30.2-0.1-0.5-0.5-0.6-0.1-0.1-0.1-0.2-0.20.3
Locomotor testing rearing0.31.11.8-0.2-0.9-0.71.31.31.4-1.01.21.11.0-1.2-0.4
Locomotion in novel chamber0.50.72.3-0.80.51.5-1.0-1.0-0.7-0.2-1.0-0.90.6-0.30.5
Locomotion in novel chamber post-restriction0.20.61.71.2-1.00.10.30.30.40.9-0.1-0.0-1.11.0-1.3
Fecal boli incidents, locomotor time 10.41.02.50.2-0.9-0.61.61.61.3-0.61.10.90.3-0.7-0.8
Change in fecal boli incidents, locomotor task0.50.51.5-0.50.1-0.7-0.1-0.10.4-0.90.70.81.2-0.71.0
Time >=10cm from walls, locomotor time 10.50.71.40.9-0.41.00.00.0-0.01.0-0.8-0.9-1.01.2-1.1
Bouts of movement, locomotor time 10.40.61.50.5-0.8-1.20.80.80.9-0.21.01.00.1-0.20.0
Total resting periods, locomotor time 10.30.41.40.2-0.5-1.20.60.60.6-0.30.91.00.0-0.40.3
Rest time, locomotor task time 10.20.20.90.6-0.6-0.10.60.60.30.7-0.1-0.1-1.00.3-0.2
Distance moved, locomotor task time 10.20.61.5-0.80.8-0.8-0.6-0.6-0.4-1.00.60.71.2-0.50.8
Vertical activity count, locomotor time 10.00.20.70.5-0.80.30.50.50.70.10.10.10.20.2-0.4
Time >=10cm from walls, locomotor time 20.41.22.20.30.71.4-1.1-1.1-1.11.2-1.5-1.5-1.01.2-0.2
Bouts of movement, locomotor time 20.10.20.7-0.20.3-0.9-0.5-0.5-0.4-0.20.40.50.0-0.10.6
Total resting periods, locomotor time 20.10.41.5-0.20.1-1.2-0.1-0.10.0-0.50.91.00.4-0.50.7
Rest time, locomotor task time 20.61.13.6-0.3-0.3-1.90.80.80.6-0.81.51.40.4-1.10.9
Distance moved, locomotor task time 20.91.22.2-0.71.31.3-1.5-1.5-1.50.2-1.2-1.2-0.00.6-0.4
Vertical activity count, locomotor time 20.20.52.50.3-0.61.60.50.50.60.3-0.7-0.80.20.3-1.2
Light reinforcement 12.913.327.54.4-5.2-1.95.25.24.90.82.62.3-0.91.6-3.8
Light reinforcement 23.47.715.93.6-4.0-1.83.93.93.50.92.01.7-1.11.5-2.6
Bone: marrow area0.00.10.3-0.40.3-0.10.30.30.3-0.20.20.20.6-0.40.0
Bone: maximum diameter0.10.20.6-0.70.70.7-0.5-0.5-0.3-0.1-0.5-0.40.2-0.50.4
Bone: maximum force0.30.61.51.0-0.81.0-0.2-0.20.21.2-0.9-0.9-0.90.9-0.0
Bone: maximum moment0.30.51.20.7-0.41.1-0.3-0.3-0.01.0-1.0-0.9-0.70.70.2
Mean time between licks in bursts0.00.30.8-0.90.40.40.20.20.0-0.90.10.10.4-0.8-0.5
Mean num. licks in bursts0.41.01.60.40.40.8-1.2-1.2-1.01.2-1.2-1.2-0.80.81.3
Cd content in liver2.62.96.2-2.52.1-1.4-0.7-0.7-0.5-2.31.21.42.4-2.21.2
Co content in liver0.81.02.8-1.71.60.4-1.0-1.0-0.8-0.8-0.3-0.21.0-1.10.7
Cu content in liver0.20.20.70.20.20.9-0.2-0.2-0.20.5-0.6-0.6-0.40.5-0.6
Fe content in liver4.35.312.03.1-1.71.70.30.30.03.4-1.9-2.0-3.53.4-2.4
K content in liver1.91.83.60.00.71.9-1.4-1.4-1.41.4-1.9-1.9-1.31.1-0.2
Mg content in liver0.91.02.2-0.50.81.5-1.1-1.1-1.10.6-1.4-1.4-0.50.30.3
Mn content in liver1.11.22.5-1.61.2-0.7-0.8-0.8-0.7-1.40.50.61.3-1.41.6
Na content in liver1.92.24.71.3-0.51.8-0.6-0.6-0.72.2-1.8-1.8-2.11.9-1.0
Rb content in liver0.40.50.90.9-0.80.90.60.60.60.9-0.5-0.6-0.60.6-0.5
Se content in liver3.03.58.02.5-1.62.00.20.20.32.8-1.8-1.9-2.32.6-1.3
Sr content in liver0.30.20.5-0.50.60.7-0.6-0.6-0.6-0.0-0.6-0.60.2-0.10.0
Zn content in liver1.11.23.0-1.41.70.4-1.5-1.5-1.6-0.4-0.6-0.60.4-0.51.1
Bone: minimum diameter0.30.71.91.4-1.20.50.70.70.91.0-0.2-0.3-0.70.8-0.6
Time in familiar zone, hab. session 10.30.40.90.6-0.90.60.70.70.90.4-0.1-0.10.10.3-1.0
Time in novel zone, hab. session 10.50.51.9-0.10.9-0.4-1.0-1.0-1.40.4-0.3-0.3-0.80.50.6
Total zone transitions, hab. session 10.20.20.6-0.70.7-0.50.10.1-0.0-0.80.40.40.5-0.60.2
Total locomotion distance, hab. session 10.40.61.3-0.91.1-0.9-0.4-0.4-0.4-0.90.50.50.7-0.80.9
Locomotion velocity, hab. session 10.40.61.2-0.91.1-1.1-0.2-0.2-0.3-1.10.80.80.8-0.90.7
Time in familiar zone, hab. session 21.41.62.80.4-1.3-1.41.61.61.7-1.01.61.51.0-0.8-0.3
Time in novel zone, hab. session 22.12.35.4-1.12.11.0-2.2-2.2-2.30.6-1.4-1.4-0.80.30.9
Total zone transitions, hab. session 20.30.40.8-0.4-0.0-0.70.60.60.6-0.80.80.80.9-0.70.2
Total locomotion distance, hab. session 20.30.51.5-0.50.4-1.20.30.30.0-0.91.00.90.6-0.70.3
Locomotion velocity, hab. session 20.20.31.1-0.10.1-1.10.50.50.2-0.60.90.80.2-0.3-0.1
Novel to familiar place preference ratio0.40.51.4-0.71.10.1-1.1-1.1-1.20.0-0.5-0.5-0.3-0.00.7
Novelty place preference0.30.41.1-0.60.9-0.0-0.9-0.9-1.00.2-0.5-0.4-0.40.00.6
Time in novel zone, NPP test0.50.61.5-0.30.80.4-1.0-1.0-1.20.6-0.9-0.9-0.90.50.3
Total zone transitions, NPP test0.10.10.5-0.50.10.70.20.20.2-0.2-0.2-0.30.6-0.50.1
Total locomotion distance, NPP test0.20.20.4-0.10.60.6-0.5-0.5-0.50.4-0.6-0.7-0.30.20.5
Locomotion velocity, NPP test0.10.10.5-0.30.30.6-0.2-0.2-0.00.1-0.4-0.40.2-0.30.7
Intraocular pressure2.33.78.3-2.72.9-1.3-1.9-1.9-2.1-2.10.60.71.6-1.82.1
Delta distance traveled before/after self-admin1.41.63.92.0-1.70.61.11.11.21.5-0.4-0.4-1.31.5-1.3
Delta ambulatory time before/after self-admin1.32.34.72.2-2.10.41.81.81.81.20.1-0.0-1.11.4-1.8
Parametrial fat weight0.40.82.5-1.1-0.0-0.00.60.60.8-1.30.70.71.5-1.6-0.1
Pavlov. Cond. lever latency0.30.30.9-0.6-0.0-0.50.20.20.2-0.80.60.60.9-0.90.3
Pavlov. Cond. magazine entry latency0.30.40.80.20.30.8-0.5-0.5-0.50.9-0.9-0.9-0.80.5-0.1
Pavlov. Cond. change in total contacts1.41.53.91.7-1.00.90.40.40.21.8-0.9-1.0-2.01.6-1.3
Pavlov. Cond. index score0.40.50.90.10.50.9-0.6-0.6-0.60.8-0.9-1.0-0.90.6-0.2
Pavlov. Cond. latency score0.10.20.3-0.10.50.5-0.4-0.4-0.40.5-0.6-0.6-0.40.20.0
Pavlov. Cond. lever contacts0.50.61.30.60.10.9-0.4-0.4-0.51.0-1.0-1.0-1.10.9-0.3
Pavlov. Cond. magazine entry number1.41.84.0-0.5-0.4-2.00.90.90.9-1.81.91.91.6-1.20.5
Pavlov. Cond. intertrial magazine entries0.20.20.9-0.50.2-0.6-0.0-0.0-0.3-1.00.60.50.6-0.40.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.1-0.00.71.0-0.7-0.7-0.80.9-1.0-1.1-0.90.6-0.2
Pavlov. Cond. response bias1.62.04.20.90.21.7-0.8-0.8-1.01.9-1.7-1.8-2.11.7-0.8
Pavlov. Cond. lever latency0.20.21.0-0.30.8-1.0-0.3-0.3-0.7-0.10.30.30.10.00.5
Pavlov. Cond. magazine entry latency0.10.20.4-0.2-0.40.50.40.40.6-0.50.10.10.3-0.4-0.6
Pavlov. Cond. change in total contacts0.10.31.80.0-0.31.3-0.1-0.10.10.2-0.7-0.8-0.30.2-0.7
Pavlov. Cond. index score0.20.21.50.0-0.51.2-0.1-0.10.20.1-0.6-0.6-0.20.1-0.6
Pavlov. Cond. latency score0.10.21.30.1-0.51.1-0.0-0.00.20.1-0.6-0.6-0.20.1-0.6
Pavlov. Cond. lever contacts0.30.41.20.6-1.10.90.60.60.90.1-0.2-0.2-0.20.1-0.8
Pavlov. Cond. magazine entry number0.10.10.70.20.2-0.80.00.0-0.10.00.40.40.20.10.5
Pavlov. Cond. intertrial magazine entries0.20.40.80.8-0.8-0.80.90.90.80.00.70.70.10.10.0
Pavlov. Cond. lever-magazine prob. diff.0.20.31.50.0-0.51.2-0.1-0.10.20.1-0.6-0.6-0.20.1-0.7
Pavlov. Cond. response bias0.30.31.60.3-0.81.30.20.20.50.2-0.6-0.6-0.30.2-0.8
Time in closed arm before self-admin1.42.55.42.3-2.10.31.71.71.51.4-0.0-0.2-1.51.6-2.1
Time in closed arm after self-admin0.91.02.61.5-1.2-0.21.11.10.90.80.20.1-1.01.1-1.6
Time in open arm before self-admin1.01.33.3-1.81.50.7-1.1-1.1-0.8-0.9-0.4-0.31.3-1.31.3
Time in open arm after self-admin0.60.71.1-0.91.10.7-1.1-1.1-1.0-0.1-0.7-0.60.5-0.31.0
Bone: periosteal estimation0.00.10.20.3-0.30.40.30.30.40.3-0.1-0.2-0.1-0.00.0
Bone: periosteal perimeter0.10.20.9-0.70.1-0.30.20.20.2-0.60.40.40.5-1.00.4
Bone: post-yield work0.10.10.4-0.20.3-0.50.10.10.2-0.10.30.40.3-0.60.7
Progressive ratio test 1 active lever presses0.40.82.50.30.21.6-0.4-0.4-0.21.0-1.2-1.2-1.10.8-0.5
Progressive ratio test 1 breakpoint0.50.82.60.30.21.6-0.5-0.5-0.31.1-1.3-1.3-1.10.8-0.6
Progressive ratio test 1 inactive lever presses0.30.73.8-0.40.31.9-0.7-0.7-0.30.5-1.4-1.3-0.1-0.10.3
Progressive ratio test 2 active lever presses0.20.31.2-0.10.41.1-0.4-0.4-0.20.5-0.9-0.9-0.50.3-0.1
Progressive ratio test 2 breakpoint0.20.30.9-0.10.50.9-0.5-0.5-0.30.4-0.8-0.8-0.50.20.1
Progressive ratio test 2 inactive lever presses0.30.92.1-1.41.30.4-1.0-1.0-0.8-0.8-0.4-0.30.7-1.01.0
Incentive Sensitization - Responses0.00.10.4-0.50.3-0.10.00.00.2-0.60.20.20.4-0.60.4
Incentive Sensitization - Breakpoint0.10.10.4-0.40.2-0.30.10.10.3-0.60.30.30.5-0.60.4
Sum of active levers in priming session hrs 5-60.30.30.6-0.60.4-0.8-0.2-0.2-0.3-0.60.50.50.6-0.70.7
Progressive ratio0.10.31.30.6-0.7-1.10.50.50.4-0.10.70.7-0.10.10.4
Food seeking constrained by brief footshock1.82.34.21.4-1.8-1.72.02.02.0-0.51.81.70.10.2-1.1
Seeking ratio, punishment vs. effort0.30.72.30.9-1.00.61.11.11.10.5-0.0-0.1-0.40.6-1.5
Retroperitoneal fat weight0.52.36.6-2.41.2-0.0-0.3-0.30.1-2.10.60.72.3-2.61.5
Reaction time number correct0.20.51.5-0.70.90.0-1.2-1.2-1.2-0.4-0.3-0.30.2-0.10.6
Reaction time mean minus median0.63.67.0-0.21.42.7-2.1-2.1-2.01.7-2.6-2.6-1.11.01.3
Reaction time mean minus median AUC0.53.26.5-0.51.52.5-2.0-2.0-1.91.5-2.5-2.4-0.90.61.3
Reaction time num false alarms2.03.310.0-3.22.70.7-1.6-1.6-1.6-1.9-0.4-0.32.0-2.11.4
Reaction time num false alarms AUC1.32.98.5-2.92.50.3-1.4-1.4-1.4-1.9-0.1-0.11.9-2.01.3
Reaction time trials correct on left0.20.51.5-0.70.90.0-1.2-1.2-1.2-0.4-0.3-0.30.2-0.10.6
Reaction time trials on left0.20.71.8-0.81.00.1-1.3-1.3-1.3-0.4-0.4-0.30.2-0.10.7
Reaction time mean2.14.78.1-1.22.52.8-2.7-2.7-2.71.3-2.8-2.8-0.60.61.1
Reaction time mean AUC1.84.47.1-1.32.52.7-2.6-2.6-2.61.2-2.7-2.6-0.50.51.0
Median of all reaction times2.33.55.8-1.22.32.3-2.4-2.4-2.41.0-2.4-2.3-0.40.40.7
Reaction time omissions1.72.85.2-1.61.82.3-2.1-2.1-1.90.1-2.0-1.90.6-0.51.5
Reaction time false alarm rate1.01.34.5-2.11.60.2-0.5-0.5-0.6-1.50.10.21.6-1.70.7
Reaction time premature initiation rate3.04.69.40.8-2.4-1.83.03.03.1-1.42.42.41.4-1.1-1.1
Reaction time premature initiations0.82.54.20.2-1.6-1.52.02.02.1-1.52.01.91.4-1.1-0.5
Std. dev. reaction times0.93.16.7-0.61.62.6-2.0-2.0-2.01.4-2.5-2.5-0.70.70.9
Reaction time trials completed0.20.71.8-0.81.00.1-1.3-1.3-1.3-0.4-0.4-0.30.2-0.10.7
Reaction time trials AUC0.20.71.8-0.81.10.1-1.3-1.3-1.3-0.4-0.4-0.40.2-0.10.7
Run reversals in cocaine runway, females0.30.40.9-0.20.50.9-0.6-0.6-0.70.4-0.8-0.8-0.50.3-0.1
Run reversals in cocaine runway, males0.30.30.8-0.00.40.2-0.8-0.8-0.70.5-0.4-0.4-0.90.40.1
Latency to leave start box in cocaine runway0.30.41.2-0.80.7-1.1-0.3-0.3-0.6-0.80.80.80.5-0.6-0.0
Latency to leave start box in cocaine runway, F0.50.62.2-0.31.0-0.3-1.3-1.3-1.50.5-0.4-0.4-0.60.30.5
Latency to leave start box in cocaine runway, M2.62.54.4-0.8-0.4-1.81.51.51.3-2.02.12.01.8-1.7-0.7
Std. dev. time between licks in bursts0.10.30.90.2-0.4-0.30.70.70.6-0.40.50.4-0.10.0-0.9
Total sessions with >9 infusions0.00.10.10.10.20.2-0.2-0.2-0.20.2-0.2-0.2-0.40.3-0.3
Short access day 1 total inactive lever presses0.20.41.40.3-0.31.2-0.1-0.10.10.6-0.7-0.8-1.00.5-1.0
Short access day 10 total inactive lever presses0.00.20.7-0.0-0.80.30.50.50.7-0.50.30.30.6-0.5-0.4
Short access day 1 total infusions0.20.30.8-0.80.90.3-0.8-0.8-0.8-0.3-0.3-0.30.1-0.30.5
Short access day 10 total infusions0.10.10.3-0.40.1-0.1-0.1-0.10.1-0.40.20.30.4-0.50.4
Short access total infusions0.10.10.3-0.50.30.3-0.1-0.1-0.0-0.4-0.1-0.10.0-0.5-0.1
Short access day 1 locomotion0.81.43.1-1.21.70.0-1.6-1.6-1.5-0.4-0.5-0.40.6-0.41.8
Short access day 10 total locomotion0.00.10.3-0.10.40.1-0.5-0.5-0.30.1-0.2-0.2-0.30.10.0
Short access total locomotion0.20.30.8-0.60.9-0.2-0.8-0.8-0.6-0.3-0.1-0.00.2-0.30.6
One hour access (0.3 mA shock)1.21.44.1-1.60.6-0.90.10.10.2-1.70.91.01.6-2.01.4
Compulsive drug intake0.50.82.0-0.70.2-1.40.20.20.0-0.91.01.00.8-1.21.3
One hour access (shock baseline)0.10.41.0-0.90.5-0.2-0.2-0.20.0-0.90.20.30.9-1.00.9
Social response proportion0.30.40.90.00.41.0-0.5-0.5-0.50.6-0.8-0.8-0.60.6-0.6
Social responses0.91.13.1-1.30.4-0.90.30.30.4-1.81.21.21.5-1.5-0.1
Social time0.30.40.80.9-0.8-0.80.60.60.50.10.70.6-0.10.6-0.6
Soleus weight0.20.51.2-0.60.1-0.60.50.50.5-1.00.70.70.9-1.10.7
Bone: stiffness0.61.12.41.0-0.71.5-0.3-0.3-0.21.6-1.3-1.4-1.41.0-0.4
Tibialis anterior weight0.61.93.2-0.71.21.7-1.8-1.8-1.70.9-1.8-1.7-1.00.30.8
Time to tail flick, vehicle, before self-admin1.11.45.6-0.40.2-2.40.50.50.4-1.31.71.81.1-0.90.7
Time to tail flick, vehicle, after self-admin0.91.73.3-0.2-0.6-1.81.41.41.4-1.21.81.81.3-1.20.4
Time to tail flick, test, before self-admin0.60.71.4-1.21.2-0.9-0.5-0.5-0.7-1.10.60.60.7-0.80.5
Time to tail flick, test, after self-admin0.60.72.31.5-1.00.00.20.20.31.3-0.3-0.3-1.21.2-0.2
Delta time to tail flick, vehicle, before/after SA0.20.30.70.1-0.6-0.20.80.80.8-0.30.50.40.2-0.3-0.4
Delta time to tail flick, test, before/after SA2.53.17.62.4-1.32.0-0.2-0.2-0.12.7-1.9-1.9-2.32.5-0.7
Tibia length1.74.610.61.20.13.3-1.6-1.6-1.32.7-3.0-3.0-2.62.1-0.2
Ambulatory time before self-admin0.72.04.6-1.31.91.3-2.0-2.0-2.20.3-1.5-1.5-0.30.00.7
Ambulatory time after self-admin1.01.63.41.3-0.51.4-0.0-0.0-0.21.8-1.4-1.5-1.81.7-1.3
Bone: tissue strength0.30.31.00.10.01.0-0.4-0.4-0.20.5-0.8-0.8-0.50.5-0.4
Total heroin consumption0.20.20.8-0.90.50.10.20.2-0.0-0.50.0-0.00.6-0.9-0.0
Bone: trabecular number0.71.43.71.9-1.7-1.71.01.00.90.71.00.9-0.91.00.3
Bone: trabecular spacing0.60.92.8-1.71.70.9-0.8-0.8-0.8-0.9-0.5-0.40.6-0.8-0.5
Bone: trabecular thickness1.62.38.22.9-2.1-0.30.90.90.91.9-0.2-0.2-1.82.2-0.5
Bone: trabecular tissue density0.20.41.5-0.61.20.0-0.8-0.8-1.0-0.4-0.2-0.20.10.00.0
Water consumed over 24 hours0.71.33.31.6-1.80.01.51.51.60.80.20.2-0.50.7-1.0
Number of responses in last shaping day1.11.53.2-1.71.5-0.3-1.1-1.1-0.8-1.30.10.21.6-1.41.8