Hub : Genes

Tekt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Tekt1 0.04 0.03 2.2e-05 0.04 0.03 0.03 0.03 3.7e-06 3.0e-05 1.6e-05 1.5e-05
2 PL gene expression Tekt1 0.08 0.05 1.2e-07 0.06 0.06 0.07 0.07 1.9e-07 4.0e-07 3.1e-08 4.7e-08
3 Adipose gene expression Tekt1 0.04 0.03 1.7e-04 0 0.01 0.01 0.01 1.5e-01 8.4e-03 2.9e-02 4.4e-02
4 RMTg gene expression Tekt1 0.12 0.09 8.5e-03 0.02 0.05 0 0.05 1.0e-01 1.7e-02 2.4e-01 1.9e-02
5 BLA gene expression Tekt1 0.07 0.05 5.8e-03 0.01 0.03 0.02 0.02 7.1e-02 8.5e-03 1.8e-02 2.2e-02
6 Brain gene expression Tekt1 0.07 0.05 2.1e-06 0.04 0.07 0.07 0.06 1.4e-04 6.9e-07 7.0e-07 1.3e-06
7 pVTA gene expression Tekt1 0.11 0.06 5.9e-09 0.1 0.05 0.1 0.1 1.4e-08 3.4e-05 4.9e-08 9.8e-09
8 NAcc gene expression Tekt1 0.11 0.08 1.7e-10 0.06 0.07 0.07 0.07 4.1e-09 2.1e-10 2.1e-10 1.8e-10
9 LHb gene expression Tekt1 0.22 0.14 1.6e-03 0.07 0.08 0.04 0.07 9.8e-03 6.7e-03 3.9e-02 8.5e-03
10 IC gene expression Tekt1 0.07 0.06 5.6e-03 0.05 0.04 0.05 0.05 4.3e-03 9.5e-03 3.3e-03 4.3e-03
11 PL mRNA stability Tekt1 0.03 0.02 3.3e-03 0.02 0.01 0.03 0.01 2.5e-03 1.3e-02 8.4e-04 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.01.93.60.9-1.11.11.31.21.61.91.71.8-1.1-0.8
Area under the delay curve0.10.10.3-0.40.2-0.2-0.3-0.2-0.4-0.6-0.4-0.50.20.0
BMI with tail0.31.01.5-0.7-1.21.21.11.21.21.00.81.0-1.0-0.6
BMI without tail0.84.26.50.7-2.01.71.91.82.32.62.42.5-2.4-1.5
Body weight2.310.115.31.2-2.92.83.02.93.43.93.93.8-3.4-2.9
Weight adjusted by age0.20.72.5-1.6-0.91.11.01.00.70.1-0.60.20.4-0.3
Bone surface0.81.52.5-0.3-1.11.51.61.51.61.31.21.5-0.2-0.3
Bone volume1.02.03.1-0.5-1.51.71.81.71.71.41.31.5-0.7-0.8
Breakpoint value in progressive ratio session0.81.52.8-0.3-1.31.41.51.41.51.71.21.4-0.5-0.4
Number of licking bursts0.20.62.50.10.9-0.6-0.6-0.6-0.6-0.4-0.6-0.51.21.6
Context. condit. distance diff. score1.31.62.3-0.7-1.51.51.51.51.51.21.01.3-1.1-1.0
Locomotion velocity, session 13.64.14.9-0.1-2.22.12.12.12.22.12.12.2-2.0-2.0
Locomotion distance, session 10.50.71.1-0.8-1.11.11.01.00.90.50.50.6-0.6-0.8
Locomotion velocity, session 20.40.51.31.2-0.30.10.20.20.50.91.00.8-1.0-0.5
Locomotion distance, session 20.40.60.90.2-0.80.70.80.80.90.90.90.9-0.9-0.7
Locomotion velocity, session 31.82.13.71.31.9-1.7-1.7-1.6-1.5-1.0-0.6-1.11.51.4
Locomotion distance, session 30.10.10.30.20.5-0.4-0.4-0.4-0.3-0.2-0.1-0.20.40.6
Stereotopy head waving bouts, day 30.00.00.20.40.10.10.10.10.20.30.40.30.0-0.0
Stereotopy head waving duration, day 30.50.61.2-0.80.6-0.4-0.5-0.4-0.8-1.1-0.9-1.01.00.5
Locomotion velocity, session 70.00.10.3-0.6-0.10.10.10.10.1-0.1-0.3-0.1-0.00.3
Locomotion distance, session 70.00.00.2-0.30.0-0.1-0.0-0.1-0.00.0-0.3-0.10.00.5
Stereotopy head waving bouts, day 71.41.72.6-0.9-1.61.61.51.51.41.00.91.2-1.1-1.1
Stereotopy head waving duration, day 71.11.31.9-0.7-1.41.41.41.41.30.91.01.1-1.0-1.0
Locomotion velocity, session 80.70.81.4-0.9-0.91.21.11.21.00.60.90.8-0.3-0.3
Locomotion distance, session 82.43.44.5-0.5-2.02.02.02.02.11.91.92.0-1.8-1.5
Degree of sensitization distance0.50.51.0-0.8-1.00.80.80.70.70.40.00.4-0.8-0.7
Degree of sensitization stereotypy1.71.92.6-0.4-1.61.51.51.51.51.31.21.4-1.4-1.2
Conditioned locomotion0.91.01.50.41.2-1.2-1.2-1.2-1.1-1.0-0.9-1.00.90.9
Cocaine response after cond. corrected0.30.41.51.2-0.1-0.2-0.1-0.10.20.80.70.6-0.9-0.7
Cocaine response after cond. not corrected0.30.40.90.9-0.40.10.20.20.40.90.70.7-0.9-0.7
Cocaine response before conditioning0.40.51.0-1.0-1.01.00.90.90.80.40.30.5-0.3-0.3
Saline control response0.40.61.4-1.2-1.10.90.90.90.70.2-0.10.4-0.6-0.7
Bone: connectivity density1.62.63.90.4-1.61.61.71.61.92.01.82.0-1.4-1.3
Bone: cortical apparent density1.11.72.80.91.5-1.7-1.6-1.7-1.5-1.1-1.1-1.20.70.7
Bone: cortical area0.30.51.0-0.40.5-0.5-0.6-0.6-0.7-1.0-0.8-0.80.70.4
Bone: cortical porosity0.80.93.82.00.0-0.3-0.2-0.20.31.11.10.8-1.2-1.1
Bone: cortical porosity0.50.52.91.70.3-0.5-0.4-0.4-0.00.70.80.4-0.8-0.6
Bone: cortical thickness1.42.33.91.51.8-2.0-1.9-1.9-1.7-1.2-1.0-1.30.70.9
Bone: cortical thickness1.01.25.72.41.1-1.4-1.3-1.3-0.80.10.2-0.1-0.5-0.1
Bone: cortical tissue density0.81.32.30.91.3-1.5-1.5-1.5-1.3-0.9-1.0-1.10.60.5
Condit. Reinf. active minus inactive responses0.20.31.61.30.3-0.6-0.4-0.5-0.10.50.10.2-0.4-0.1
Condit. Reinf. active-inactive response ratio0.20.20.90.90.2-0.5-0.4-0.4-0.10.4-0.00.1-0.3-0.3
Condit. Reinf. active responses0.20.21.51.20.1-0.4-0.3-0.40.00.60.10.3-0.6-0.3
Condit. Reinf. inactive responses0.00.00.10.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.00.2
Incentive salience index mean0.40.63.01.70.0-0.5-0.3-0.40.20.90.50.6-1.0-0.6
Condit. Reinf. lever presses1.11.65.02.2-0.50.00.20.10.81.71.41.3-1.8-1.5
Condit. Reinf. active minus inactive responses0.10.21.21.10.2-0.3-0.2-0.30.10.60.40.4-0.3-0.0
Condit. Reinf. active-inactive response ratio0.20.31.81.30.4-0.6-0.5-0.6-0.20.40.10.1-0.2-0.2
Condit. Reinf. active responses0.10.10.40.60.2-0.2-0.1-0.10.10.40.30.3-0.00.2
Condit. Reinf. inactive responses0.20.20.8-0.90.10.10.00.0-0.2-0.4-0.4-0.30.70.9
Condit. Reinf. lever presses0.81.21.6-0.11.1-1.1-1.1-1.1-1.2-1.1-1.3-1.21.11.3
Condit. Reinf. lever reinforcers received0.00.10.20.50.3-0.3-0.2-0.3-0.10.20.00.10.20.4
Conditioned reinforcement - actives0.10.60.8-0.6-0.90.90.90.90.80.60.70.6-0.6-0.7
Conditioned reinforcement - inactives0.71.96.4-2.5-1.61.91.81.71.3-0.0-0.20.60.20.2
Conditioned locomotion0.60.94.8-2.2-0.20.40.20.3-0.4-1.4-1.0-0.90.70.3
Patch foraging indifference point 0 sec0.20.52.01.40.7-1.0-0.9-1.0-0.50.5-0.0-0.00.10.5
Patch foraging indifference point AUC0.20.51.9-1.4-0.20.20.10.1-0.3-0.8-1.1-0.80.8-0.1
Delay disc. indifference point, 0s delay1.01.22.1-1.4-1.51.31.31.31.00.40.40.6-0.9-1.1
Delay disc. indifference point, 16s delay0.10.20.7-0.60.0-0.1-0.2-0.1-0.5-0.8-0.2-0.6-0.1-0.3
Delay disc. indifference point, 2s delay0.20.20.30.10.4-0.5-0.5-0.5-0.5-0.4-0.4-0.40.10.4
Delay disc. indifference point, 24s delay0.40.61.10.81.0-0.9-0.9-0.8-0.7-0.4-0.2-0.50.80.9
Delay disc. indifference point, 4s delay0.10.20.7-0.8-0.40.50.50.40.3-0.0-0.30.00.30.0
Delay disc. indifference point, 8s delay0.00.00.1-0.10.1-0.1-0.1-0.1-0.2-0.2-0.1-0.2-0.0-0.1
Indifference point function ln k0.61.89.43.11.4-1.5-1.3-1.3-0.50.71.20.5-0.60.6
Indifference point function log k0.61.89.43.11.4-1.5-1.3-1.3-0.50.71.20.5-0.60.6
Patch foraging total patch changes 0 sec0.10.41.31.20.6-0.9-0.7-0.8-0.40.5-0.1-0.00.00.5
Patch foraging total patch changes 12 sec0.30.31.6-1.3-0.80.60.60.50.30.0-0.7-0.10.1-0.2
Patch foraging total patch changes 18 sec0.10.10.4-0.6-0.60.30.40.30.20.1-0.4-0.0-0.1-0.6
Patch foraging total patch changes 24 sec0.10.20.9-0.9-0.0-0.1-0.1-0.1-0.3-0.5-0.8-0.50.50.2
Patch foraging total patch changes 6 sec0.40.62.8-1.7-0.30.20.10.0-0.3-0.8-1.4-0.80.70.1
Patch foraging time to switch 0 sec0.41.52.7-1.6-1.61.61.61.61.30.50.30.7-0.6-1.1
Patch foraging water rate 0 sec0.31.22.10.61.4-1.3-1.3-1.3-1.1-0.8-0.7-0.90.71.5
Patch foraging water rate 12 sec0.20.71.0-0.5-0.91.01.01.01.00.80.60.9-0.9-0.3
Patch foraging water rate 18 sec0.30.71.80.9-0.30.30.40.40.81.21.31.1-1.20.1
Patch foraging water rate 24 sec0.10.21.3-0.60.10.20.10.10.0-0.3-0.2-0.10.11.1
Patch foraging water rate 6 sec0.30.41.90.00.8-0.6-0.6-0.5-0.5-0.6-0.1-0.30.31.4
Seeking ratio, delayed vs. immediate footshock0.50.71.10.51.0-1.0-1.0-1.0-1.0-0.7-0.6-0.80.70.5
Distance traveled before self-admin0.30.71.8-1.10.2-0.4-0.5-0.5-0.9-1.3-1.1-1.20.3-0.4
Distance traveled after self-admin1.22.17.9-2.8-1.71.81.61.70.9-0.6-0.5-0.0-0.2-1.7
Extensor digitorum longus weight2.08.013.1-3.3-3.63.63.53.52.81.41.31.9-2.0-2.7
Bone: elastic displacement0.60.81.20.00.7-1.0-1.0-1.0-1.1-1.0-1.1-1.10.20.1
Bone: elastic work1.51.93.00.91.5-1.7-1.7-1.7-1.6-1.4-1.2-1.40.80.7
Bone: endosteal estimation0.81.99.5-3.1-1.21.71.51.60.8-0.5-0.5-0.00.90.2
Bone: endosteal perimeter0.81.98.2-2.9-1.41.81.71.71.0-0.3-0.30.20.8-0.1
Epididymis fat weight4.020.329.4-1.7-5.45.05.15.05.04.13.74.4-4.6-4.5
Delta time in closed arm before/after self-admin0.10.10.3-0.6-0.20.30.20.20.0-0.20.2-0.10.1-0.1
Delta time in open arm before/after self-admin0.30.40.7-0.6-0.90.70.70.60.60.5-0.20.4-0.5-0.7
Diff in mean of infusions in LGA sessions0.71.32.30.3-1.11.11.21.11.31.51.41.4-1.0-0.6
Delay discount exponential model param0.10.10.20.2-0.30.30.30.30.40.50.30.4-0.3-0.3
Extinction: sum of active levers before priming1.32.04.3-0.4-1.71.61.61.61.51.31.01.3-1.1-2.1
Active lever presses in extinction session 62.82.86.50.2-1.81.61.61.61.61.61.71.6-1.8-2.5
Bone: final force0.10.20.3-0.5-0.30.50.50.50.3-0.1-0.20.10.60.2
Bone: final moment0.10.20.5-0.7-0.30.50.40.40.2-0.3-0.4-0.10.60.2
Food consumed during 24 hour testing period0.20.31.31.10.1-0.3-0.3-0.2-0.00.40.80.4-0.9-0.5
Glucose3.55.58.1-0.62.2-2.2-2.3-2.3-2.5-2.5-2.8-2.72.22.6
Heart weight1.21.92.6-0.3-1.51.51.61.51.61.51.41.5-1.3-1.1
Delay discount hyperbolic model param0.10.10.20.1-0.30.30.30.30.40.40.30.4-0.4-0.4
Intermittent access intake day 1-15 change0.20.92.7-1.60.2-0.1-0.3-0.2-0.8-1.5-1.5-1.30.5-0.5
Intermittent access intake escalation0.21.23.5-1.90.1-0.1-0.3-0.3-0.9-1.7-1.8-1.40.7-0.6
Intermittent access intake escalation 20.91.53.2-1.10.8-0.8-1.0-0.9-1.3-1.8-1.8-1.70.9-0.0
Intermitt. access day 1 inactive lever presses0.33.98.2-1.81.3-1.0-1.1-1.1-1.5-2.4-2.9-2.12.72.6
Intermitt. access day 15 inactive lever presses0.10.72.2-0.60.7-0.3-0.4-0.4-0.5-0.9-1.1-0.81.51.2
Intermitt. access escalation Index0.30.82.20.4-0.80.70.80.70.91.51.11.1-0.9-0.7
Intermittent access day 1 total infusions0.41.33.7-1.9-1.51.51.51.51.00.10.00.5-0.2-0.7
Intermittent access day 15 total infusions0.92.211.9-3.4-1.51.61.41.40.6-1.0-1.1-0.50.4-1.1
Intermittent access terminal intake (last 3 days)1.32.28.6-2.9-1.81.81.71.71.0-0.4-0.40.1-0.4-1.5
Intermittent access total infusions1.41.76.1-2.5-1.61.51.41.40.8-0.5-0.40.0-0.4-1.5
Intermittent access day 1 locomotion0.61.24.0-2.0-1.21.51.41.41.00.10.10.50.30.1
Intermittent access day 15 total locomotion0.31.37.6-2.8-0.81.21.01.10.4-1.0-0.7-0.30.5-0.1
Intermittent access total locomotion0.91.15.2-2.3-1.01.31.11.20.6-0.6-0.4-0.00.4-0.4
Intermittent access standard deviation0.41.910.6-3.3-0.91.21.01.10.1-1.3-1.3-0.90.9-0.7
Left kidney weight0.00.10.2-0.10.00.20.10.2-0.0-0.5-0.1-0.10.3-0.4
Right kidney weight0.00.30.60.2-0.50.60.60.60.60.20.60.6-0.6-0.8
Cocaine induced anxiety0.10.30.60.70.8-0.6-0.6-0.6-0.5-0.4-0.3-0.40.60.4
Post-drug Anxiety0.70.82.01.2-0.60.20.40.30.61.10.80.9-1.4-1.3
Baseline Anxiety0.81.42.80.2-1.30.91.00.91.21.51.01.2-1.7-1.1
Tail length1.68.814.51.6-2.62.42.62.63.13.83.83.6-3.2-2.6
Length with tail2.19.116.02.0-2.52.42.62.63.13.84.03.7-3.1-2.8
Length without tail0.84.27.00.9-1.91.92.02.02.22.52.62.4-2.0-1.9
Times rat made contact with spout0.40.41.71.30.7-0.9-0.8-0.8-0.50.20.1-0.1-0.10.1
Lifetime Intake1.82.28.2-2.9-1.81.91.81.81.1-0.3-0.40.2-0.2-1.3
Liver weight, left4.27.212.82.1-2.22.02.22.12.73.33.63.3-3.0-2.5
Liver weight, right5.08.811.50.7-3.02.93.03.03.33.33.33.4-2.9-2.8
Locomotor activity0.30.51.3-1.1-1.01.00.90.90.80.2-0.00.4-0.4-0.2
Locomotor testing distance0.82.05.9-2.4-1.91.91.81.71.30.2-0.20.5-0.7-0.9
Locomotor testing rearing0.51.77.1-2.7-1.61.51.41.40.8-0.3-0.8-0.0-0.3-0.9
Locomotion in novel chamber1.72.36.0-2.00.6-0.8-1.0-0.9-1.5-2.5-2.4-2.00.80.5
Locomotion in novel chamber post-restriction0.10.30.60.20.5-0.8-0.7-0.8-0.7-0.6-0.6-0.70.20.1
Fecal boli incidents, locomotor time 10.10.20.50.70.4-0.5-0.5-0.4-0.4-0.10.2-0.2-0.3-0.3
Change in fecal boli incidents, locomotor task0.40.41.30.50.8-0.6-0.5-0.6-0.4-0.2-0.4-0.31.11.1
Time >=10cm from walls, locomotor time 10.00.10.20.50.3-0.2-0.2-0.2-0.00.30.30.20.00.0
Bouts of movement, locomotor time 10.30.41.61.30.0-0.3-0.2-0.20.00.50.60.3-0.9-0.7
Total resting periods, locomotor time 10.50.63.21.80.7-0.9-0.8-0.8-0.40.30.50.1-0.5-0.1
Rest time, locomotor task time 10.61.01.80.71.4-1.2-1.2-1.2-1.1-0.8-0.6-0.91.10.9
Distance moved, locomotor task time 10.20.51.1-1.0-1.00.90.90.90.70.30.00.4-0.4-0.2
Vertical activity count, locomotor time 10.10.71.3-1.1-1.11.11.11.00.90.60.20.6-0.6-0.2
Time >=10cm from walls, locomotor time 20.10.30.60.60.8-0.6-0.6-0.6-0.4-0.00.1-0.10.60.5
Bouts of movement, locomotor time 20.10.41.91.40.8-0.8-0.8-0.8-0.40.10.0-0.10.30.3
Total resting periods, locomotor time 20.10.31.51.20.5-0.6-0.5-0.5-0.20.30.30.10.0-0.1
Rest time, locomotor task time 20.40.61.30.91.2-1.0-1.0-0.9-0.8-0.3-0.1-0.50.70.7
Distance moved, locomotor task time 20.60.73.1-1.8-1.11.00.90.90.5-0.2-0.40.0-0.4-0.6
Vertical activity count, locomotor time 20.20.51.2-1.1-1.00.90.90.80.70.20.00.4-0.6-0.3
Light reinforcement 10.31.35.2-2.3-1.41.41.31.30.9-0.1-0.40.2-0.5-0.4
Light reinforcement 20.00.10.5-0.7-0.20.10.10.1-0.1-0.5-0.5-0.30.10.2
Bone: marrow area0.71.89.1-3.0-1.21.71.51.50.8-0.5-0.5-0.00.90.2
Bone: maximum diameter0.20.42.5-1.6-0.20.40.30.3-0.1-0.9-0.7-0.50.70.1
Bone: maximum force0.10.31.0-1.0-0.40.70.60.60.4-0.2-0.30.00.50.2
Bone: maximum moment0.20.31.6-1.3-0.40.60.50.50.2-0.4-0.5-0.20.50.2
Mean time between licks in bursts0.52.84.0-0.8-2.01.81.81.81.71.41.51.5-1.9-1.9
Mean num. licks in bursts0.20.41.90.6-0.40.10.10.10.30.50.50.4-1.1-1.4
Cd content in liver0.80.93.0-1.7-1.11.31.21.20.90.10.10.40.1-0.1
Co content in liver0.30.41.30.2-0.60.40.40.50.50.50.70.6-0.9-1.2
Cu content in liver1.21.42.31.41.5-1.5-1.4-1.5-1.1-0.4-0.5-0.70.91.4
Fe content in liver0.81.01.40.2-1.01.11.11.11.21.11.11.2-0.8-0.9
K content in liver0.80.81.80.9-0.50.60.60.60.81.01.31.1-0.9-1.0
Mg content in liver0.10.10.60.70.3-0.3-0.3-0.3-0.10.20.30.1-0.1-0.1
Mn content in liver0.70.73.31.81.0-1.1-1.0-1.0-0.70.10.3-0.1-0.20.1
Na content in liver0.10.10.2-0.30.0-0.1-0.2-0.1-0.3-0.5-0.3-0.4-0.2-0.3
Rb content in liver0.50.61.1-1.0-1.01.11.01.00.80.40.20.5-0.3-0.5
Se content in liver0.60.71.50.41.1-0.9-0.9-0.9-0.8-0.6-0.6-0.71.11.2
Sr content in liver1.21.11.6-0.9-1.31.21.21.21.00.70.60.8-1.0-1.2
Zn content in liver0.30.30.90.6-0.30.40.50.40.70.90.80.8-0.20.1
Bone: minimum diameter0.61.14.4-2.1-1.21.41.31.40.8-0.10.00.30.1-0.4
Time in familiar zone, hab. session 10.20.20.5-0.70.1-0.1-0.1-0.1-0.3-0.5-0.7-0.50.40.5
Time in novel zone, hab. session 10.10.10.60.80.1-0.1-0.1-0.00.10.50.60.4-0.4-0.3
Total zone transitions, hab. session 11.62.39.6-3.1-1.91.91.81.81.2-0.1-0.30.3-0.5-0.6
Total locomotion distance, hab. session 10.20.30.7-0.8-0.70.60.60.60.50.2-0.00.3-0.6-0.2
Locomotion velocity, hab. session 10.20.30.9-1.0-0.70.60.60.50.40.0-0.20.1-0.4-0.3
Time in familiar zone, hab. session 20.20.20.80.9-0.1-0.00.00.00.20.50.50.4-0.3-0.6
Time in novel zone, hab. session 20.50.51.2-0.30.7-0.7-0.7-0.7-0.7-0.7-0.9-0.80.61.1
Total zone transitions, hab. session 21.31.73.0-1.7-1.71.71.61.61.30.60.40.8-0.9-0.9
Total locomotion distance, hab. session 20.30.30.7-0.8-0.90.70.70.70.60.30.10.3-0.6-0.4
Locomotion velocity, hab. session 20.20.30.7-0.8-0.80.70.70.70.50.20.10.3-0.6-0.4
Novel to familiar place preference ratio0.10.20.4-0.60.2-0.1-0.2-0.2-0.3-0.5-0.7-0.50.40.5
Novelty place preference0.00.00.1-0.30.0-0.0-0.0-0.0-0.1-0.1-0.3-0.10.10.3
Time in novel zone, NPP test0.00.00.0-0.2-0.10.10.10.10.10.1-0.10.1-0.10.1
Total zone transitions, NPP test1.31.95.2-2.3-1.81.81.71.71.20.30.00.5-0.8-0.9
Total locomotion distance, NPP test0.20.21.0-1.0-0.10.00.0-0.0-0.2-0.6-0.8-0.50.20.3
Locomotion velocity, NPP test0.40.61.4-1.00.3-0.4-0.5-0.5-0.7-1.1-1.2-1.00.70.7
Intraocular pressure0.71.23.6-1.80.1-0.2-0.3-0.3-0.7-1.6-1.9-1.30.90.2
Delta distance traveled before/after self-admin2.62.95.1-1.5-2.12.32.22.21.91.00.81.4-0.8-1.5
Delta ambulatory time before/after self-admin1.01.72.9-0.9-1.61.71.71.71.50.90.51.1-0.7-1.5
Parametrial fat weight8.620.330.2-2.0-5.55.15.15.15.04.03.44.2-4.6-4.5
Pavlov. Cond. lever latency0.50.73.8-2.0-0.61.00.80.90.4-0.4-0.1-0.10.50.3
Pavlov. Cond. magazine entry latency0.91.27.52.70.8-1.0-0.9-0.9-0.30.80.80.5-0.5-0.3
Pavlov. Cond. change in total contacts1.21.32.41.41.3-1.6-1.5-1.5-1.2-0.5-0.8-0.80.50.8
Pavlov. Cond. index score0.70.95.52.30.3-0.7-0.5-0.6-0.00.90.70.6-0.9-0.7
Pavlov. Cond. latency score0.81.06.32.50.3-0.6-0.4-0.50.11.10.90.8-1.0-0.8
Pavlov. Cond. lever contacts0.50.63.81.90.5-0.9-0.7-0.8-0.30.50.10.1-0.6-0.4
Pavlov. Cond. magazine entry number0.50.73.5-1.9-0.81.10.91.00.5-0.3-0.10.00.20.1
Pavlov. Cond. intertrial magazine entries1.01.26.4-2.5-1.21.21.11.10.6-0.4-0.6-0.1-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.60.85.12.30.5-0.8-0.7-0.8-0.20.70.50.4-0.7-0.5
Pavlov. Cond. response bias0.60.74.82.20.5-0.9-0.7-0.8-0.30.60.40.3-0.6-0.4
Pavlov. Cond. lever latency1.92.63.1-0.1-1.71.71.71.71.81.71.71.7-1.6-1.6
Pavlov. Cond. magazine entry latency0.60.81.30.81.1-1.1-1.1-1.1-1.0-0.5-0.6-0.80.90.9
Pavlov. Cond. change in total contacts0.51.21.70.81.3-1.3-1.3-1.3-1.2-0.9-0.8-1.01.00.8
Pavlov. Cond. index score1.72.73.30.21.7-1.7-1.7-1.7-1.8-1.7-1.8-1.81.71.6
Pavlov. Cond. latency score2.03.23.90.11.9-1.8-1.8-1.8-2.0-1.9-1.9-2.01.91.7
Pavlov. Cond. lever contacts1.01.41.80.31.3-1.3-1.3-1.3-1.3-1.1-1.2-1.21.11.3
Pavlov. Cond. magazine entry number0.70.91.2-0.6-1.11.11.11.11.00.80.90.9-1.0-0.7
Pavlov. Cond. intertrial magazine entries0.51.11.8-0.9-1.31.31.31.21.20.80.60.9-0.9-0.7
Pavlov. Cond. lever-magazine prob. diff.1.72.73.30.21.8-1.7-1.7-1.7-1.8-1.7-1.7-1.81.71.5
Pavlov. Cond. response bias1.31.82.40.71.6-1.6-1.5-1.6-1.4-1.1-1.2-1.31.21.3
Time in closed arm before self-admin0.30.52.71.6-0.2-0.00.10.00.51.10.70.8-0.7-0.4
Time in closed arm after self-admin0.20.20.50.70.6-0.6-0.6-0.6-0.5-0.20.1-0.20.20.6
Time in open arm before self-admin1.72.04.0-0.11.6-1.3-1.4-1.3-1.4-1.4-1.1-1.41.82.0
Time in open arm after self-admin0.91.02.9-1.20.5-0.4-0.5-0.5-0.8-1.2-1.7-1.21.11.0
Bone: periosteal estimation0.40.94.9-2.2-0.71.10.91.00.4-0.7-0.6-0.20.80.2
Bone: periosteal perimeter0.20.52.3-1.5-0.60.80.70.70.3-0.5-0.4-0.20.6-0.1
Bone: post-yield work0.81.32.0-0.3-1.21.31.41.31.41.41.11.3-0.6-0.5
Progressive ratio test 1 active lever presses0.30.51.2-1.1-1.00.80.80.80.5-0.10.10.2-0.6-0.9
Progressive ratio test 1 breakpoint0.40.61.4-1.2-1.10.90.90.90.6-0.10.10.2-0.6-1.0
Progressive ratio test 1 inactive lever presses0.41.05.9-2.4-0.71.00.70.90.3-1.2-0.9-0.40.30.2
Progressive ratio test 2 active lever presses0.20.20.5-0.7-0.70.60.60.60.4-0.00.00.1-0.2-0.7
Progressive ratio test 2 breakpoint0.20.30.6-0.8-0.80.70.70.70.4-0.00.10.2-0.2-0.8
Progressive ratio test 2 inactive lever presses0.31.15.6-2.4-1.11.21.01.00.6-0.6-0.8-0.10.00.1
Incentive Sensitization - Responses0.00.10.3-0.2-0.20.40.40.40.30.20.10.20.60.2
Incentive Sensitization - Breakpoint0.00.10.4-0.2-0.20.40.40.40.30.20.10.20.60.2
Sum of active levers in priming session hrs 5-63.12.96.11.0-1.51.21.31.21.62.11.81.8-2.1-2.5
Progressive ratio0.10.41.3-1.1-0.30.10.10.0-0.3-0.8-1.1-0.70.4-0.6
Food seeking constrained by brief footshock0.10.10.60.10.5-0.3-0.3-0.3-0.4-0.2-0.1-0.30.80.4
Seeking ratio, punishment vs. effort0.10.30.91.00.7-0.5-0.5-0.4-0.20.30.60.20.10.9
Retroperitoneal fat weight0.31.22.3-0.9-1.51.31.31.31.20.70.40.8-1.1-1.0
Reaction time number correct0.10.30.4-0.4-0.40.50.50.50.60.40.50.6-0.50.6
Reaction time mean minus median0.21.22.10.41.1-1.3-1.2-1.3-1.2-1.0-1.4-1.20.90.7
Reaction time mean minus median AUC0.10.30.70.20.5-0.6-0.6-0.7-0.6-0.5-0.9-0.60.50.5
Reaction time num false alarms0.71.22.00.91.2-1.4-1.3-1.4-1.2-0.7-1.0-1.00.80.9
Reaction time num false alarms AUC0.51.11.70.71.2-1.3-1.3-1.3-1.1-0.7-0.9-0.90.81.0
Reaction time trials correct on left0.10.30.4-0.4-0.40.50.50.50.60.40.50.6-0.50.6
Reaction time trials on left0.10.30.4-0.4-0.40.50.50.50.60.40.50.6-0.50.7
Reaction time mean0.20.40.60.50.7-0.8-0.7-0.8-0.7-0.5-0.6-0.60.60.5
Reaction time mean AUC0.40.91.30.61.1-1.1-1.1-1.1-1.1-0.8-1.0-1.01.00.7
Median of all reaction times0.10.20.20.40.5-0.5-0.4-0.5-0.4-0.3-0.3-0.40.50.3
Reaction time omissions0.00.10.1-0.4-0.30.30.30.20.20.1-0.20.1-0.10.0
Reaction time false alarm rate0.71.01.60.81.1-1.3-1.2-1.3-1.2-0.7-1.0-1.00.80.5
Reaction time premature initiation rate0.30.51.91.40.6-0.6-0.5-0.6-0.10.70.60.3-0.11.0
Reaction time premature initiations0.10.41.51.00.4-0.3-0.2-0.20.10.80.90.6-0.21.2
Std. dev. reaction times0.51.72.51.01.5-1.6-1.5-1.6-1.4-0.9-1.2-1.21.01.0
Reaction time trials completed0.10.30.4-0.4-0.40.50.50.50.60.40.50.6-0.50.7
Reaction time trials AUC0.10.20.4-0.3-0.40.40.40.50.50.40.50.5-0.50.6
Run reversals in cocaine runway, females0.10.20.80.20.5-0.1-0.2-0.1-0.2-0.3-0.4-0.20.90.5
Run reversals in cocaine runway, males0.60.73.9-2.0-0.60.50.40.4-0.1-0.9-1.2-0.70.20.1
Latency to leave start box in cocaine runway0.10.10.40.30.3-0.2-0.1-0.1-0.10.20.20.00.40.7
Latency to leave start box in cocaine runway, F0.20.30.90.8-0.10.20.30.20.41.00.80.60.20.4
Latency to leave start box in cocaine runway, M0.20.10.9-1.0-0.30.20.10.1-0.1-0.5-0.4-0.3-0.1-0.1
Std. dev. time between licks in bursts0.50.91.6-0.7-1.21.00.91.00.90.60.70.7-1.3-1.2
Total sessions with >9 infusions0.91.13.7-1.9-1.21.31.31.20.8-0.1-0.30.20.3-1.0
Short access day 1 total inactive lever presses0.30.62.4-1.6-0.30.60.50.50.3-0.4-0.7-0.21.01.0
Short access day 10 total inactive lever presses0.21.43.2-1.31.0-0.4-0.6-0.5-1.0-1.5-1.3-1.31.81.3
Short access day 1 total infusions0.61.26.4-2.5-0.80.90.70.80.1-1.2-1.4-0.70.6-0.7
Short access day 10 total infusions0.30.62.9-1.7-0.60.70.70.60.2-0.7-0.7-0.30.6-0.3
Short access total infusions1.01.57.6-2.8-1.21.31.21.20.5-0.8-1.0-0.30.5-0.6
Short access day 1 locomotion0.40.72.4-1.60.1-0.0-0.2-0.1-0.5-1.3-1.3-1.00.80.2
Short access day 10 total locomotion0.21.03.3-1.80.20.20.00.1-0.4-1.3-1.3-1.01.50.7
Short access total locomotion0.81.23.0-1.50.6-0.2-0.3-0.2-0.8-1.6-1.2-1.21.71.0
One hour access (0.3 mA shock)1.41.63.8-1.9-1.71.61.51.51.10.20.00.5-0.8-1.5
Compulsive drug intake0.40.61.80.6-0.60.40.60.50.81.31.11.0-0.7-0.3
One hour access (shock baseline)0.20.62.5-1.6-0.90.90.80.90.4-0.4-0.4-0.1-0.4-0.9
Social response proportion2.12.65.62.0-0.90.80.90.91.52.42.12.0-1.9-1.3
Social responses2.22.94.5-0.7-2.11.92.01.92.01.81.21.7-1.7-1.5
Social time1.62.53.3-0.3-1.81.71.71.71.81.61.31.7-1.7-1.5
Soleus weight4.112.113.9-0.0-3.73.53.63.63.73.53.73.7-3.6-3.7
Bone: stiffness1.73.15.0-0.7-1.92.22.22.22.21.71.61.9-0.8-1.0
Tibialis anterior weight3.211.016.7-2.2-4.13.93.93.93.52.52.32.9-3.2-3.4
Time to tail flick, vehicle, before self-admin1.01.22.90.6-0.81.01.11.01.21.71.61.4-0.6-0.4
Time to tail flick, vehicle, after self-admin0.10.20.3-0.1-0.50.50.50.50.50.40.30.5-0.3-0.2
Time to tail flick, test, before self-admin0.91.06.02.40.9-1.0-0.9-0.9-0.30.80.80.4-0.60.4
Time to tail flick, test, after self-admin0.30.31.11.10.6-0.8-0.7-0.7-0.40.10.2-0.1-0.30.1
Delta time to tail flick, vehicle, before/after SA0.70.82.5-1.60.2-0.0-0.2-0.1-0.5-1.4-1.4-1.00.70.5
Delta time to tail flick, test, before/after SA0.30.42.6-1.6-0.30.40.20.3-0.1-0.8-0.7-0.50.4-0.2
Tibia length0.61.64.12.0-0.40.40.50.51.01.71.91.6-1.2-1.1
Ambulatory time before self-admin0.20.51.3-0.90.2-0.5-0.5-0.5-0.9-1.1-0.9-1.10.1-0.5
Ambulatory time after self-admin1.01.64.0-1.6-1.61.51.41.51.00.20.20.5-0.9-2.0
Bone: tissue strength0.60.61.7-0.70.6-0.4-0.4-0.4-0.6-0.8-0.9-0.81.31.2
Total heroin consumption3.43.97.00.5-1.82.02.12.02.32.62.32.4-1.3-1.5
Bone: trabecular number0.81.42.81.3-0.90.70.80.81.21.71.51.5-1.4-1.0
Bone: trabecular spacing0.60.82.6-1.00.7-0.2-0.3-0.3-0.6-1.0-0.9-0.81.61.4
Bone: trabecular thickness0.30.40.70.2-0.60.60.70.70.80.80.80.8-0.6-0.3
Bone: trabecular tissue density1.72.94.20.82.0-1.9-1.9-1.9-1.9-1.6-1.4-1.61.81.6
Water consumed over 24 hours0.71.45.52.31.5-1.4-1.3-1.2-0.70.40.70.10.31.1
Number of responses in last shaping day1.01.33.6-1.10.8-0.6-0.8-0.7-1.0-1.7-1.9-1.30.90.8