Tekt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	mRNA stability	Tekt1	0.04	0.03	5.4e-04	0.03	0.02	0.02	0.02	1.9e-04	1.2e-03	4.6e-03	1.7e-03
2	pVTA	mRNA stability	Tekt1	0.11	0.08	1.9e-03	0.07	0.03	0.06	0.06	5.4e-04	1.8e-02	1.7e-03	1.3e-03
3	Adipose	gene expression	Tekt1	0.04	0.03	2.1e-04	0.03	0.01	0.02	0.02	2.9e-04	6.8e-03	1.1e-03	3.0e-03
4	PL	gene expression	Tekt1	0.07	0.05	3.7e-07	0.06	0.06	0.06	0.06	4.8e-07	9.7e-07	1.5e-07	4.1e-07
5	RMTg	gene expression	Tekt1	0.13	0.1	5.2e-03	0.02	0.05	0.05	0.06	8.9e-02	1.6e-02	1.8e-02	1.1e-02
6	BLA	gene expression	Tekt1	0.07	0.06	6.0e-03	0.01	0.03	0.04	0.02	6.9e-02	7.4e-03	5.8e-03	2.0e-02
7	Brain	gene expression	Tekt1	0.08	0.05	6.9e-07	0.04	0.07	0.07	0.07	1.8e-04	4.7e-07	4.6e-07	7.5e-07
8	NAcc	gene expression	Tekt1	0.11	0.07	3.5e-10	0.08	0.09	0.08	0.09	1.7e-09	4.0e-10	1.1e-09	3.8e-10
9	LHb	gene expression	Tekt1	0.22	0.14	1.6e-03	0.07	0.08	0.05	0.08	7.5e-03	7.1e-03	3.0e-02	7.4e-03
10	pVTA	gene expression	Tekt1	0.13	0.09	1.2e-04	0.08	0.12	0.09	0.11	1.9e-04	7.2e-06	1.0e-04	1.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.9	1.6	2.7	0.6	-0.5	-0.7	-1.4	1.2	-1.1	-1.5	1.5	1.6	1.6
Area under the delay curve	0.1	0.1	0.2	-0.2	0.2	0.1	0.3	-0.3	0.2	0.4	-0.2	-0.4	-0.4
BMI with tail	0.2	0.8	1.1	-1.0	0.7	-1.1	-1.0	1.0	-0.9	-1.0	0.5	0.7	0.7
BMI without tail	0.6	1.2	2.0	-0.9	0.7	-1.1	-1.4	1.3	-1.1	-1.3	0.7	1.1	1.0
Body weight	1.3	5.4	8.7	0.4	-0.5	-1.6	-2.5	2.5	-2.3	-2.8	2.9	2.9	3.0
Weight adjusted by age	1.6	1.8	3.0	-1.7	1.6	-1.7	-1.6	1.6	-1.3	-1.2	0.3	0.8	0.6
Bone surface	1.0	1.7	2.7	-0.5	0.8	-1.4	-1.6	1.6	-1.5	-1.5	1.0	1.3	1.2
Bone volume	1.2	2.1	3.3	-0.8	1.0	-1.7	-1.8	1.8	-1.7	-1.7	1.0	1.3	1.3
Breakpoint value in progressive ratio session	0.9	1.0	1.9	-0.0	-0.2	-0.7	-1.4	1.2	-0.8	-1.3	0.9	1.2	1.2
Number of licking bursts	0.3	0.3	0.6	0.2	-0.3	0.6	0.6	-0.6	0.8	0.6	-0.7	-0.5	-0.5
Context. condit. distance diff. score	1.2	1.5	2.3	-0.5	0.6	-1.3	-1.5	1.4	-1.4	-1.4	1.1	1.2	1.2
Locomotion velocity, session 1	3.2	3.5	5.0	0.0	-0.0	-1.6	-2.2	2.1	-2.1	-2.1	2.1	2.2	2.2
Locomotion distance, session 1	0.7	0.9	1.6	-0.9	0.7	-1.3	-1.2	1.1	-1.1	-0.9	0.5	0.7	0.6
Locomotion velocity, session 2	0.4	0.4	1.1	0.9	-1.1	0.0	-0.3	0.2	-0.3	-0.5	0.9	0.8	0.8
Locomotion distance, session 2	0.5	0.6	1.0	0.1	-0.3	-0.6	-0.9	0.9	-0.7	-0.9	1.0	1.0	1.0
Locomotion velocity, session 3	1.7	2.0	3.5	1.4	-1.0	1.9	1.8	-1.7	1.4	1.7	-0.8	-1.2	-1.1
Locomotion distance, session 3	0.1	0.1	0.2	0.3	-0.3	0.3	0.4	-0.4	0.3	0.3	-0.1	-0.2	-0.2
Stereotopy head waving bouts, day 3	0.0	0.1	0.1	0.4	-0.3	0.1	-0.1	0.1	-0.2	-0.0	0.4	0.3	0.3
Stereotopy head waving duration, day 3	0.5	0.6	1.3	-0.8	0.9	0.1	0.6	-0.5	0.3	0.9	-1.1	-1.0	-1.1
Locomotion velocity, session 7	0.1	0.1	0.4	-0.7	0.4	-0.3	-0.1	0.1	-0.0	-0.1	-0.3	-0.1	-0.1
Locomotion distance, session 7	0.0	0.0	0.1	-0.3	0.0	0.1	0.0	-0.1	0.3	-0.1	-0.2	-0.0	-0.0
Stereotopy head waving bouts, day 7	1.0	1.1	1.6	-0.8	0.8	-1.2	-1.3	1.2	-1.3	-1.1	0.8	0.9	0.9
Stereotopy head waving duration, day 7	1.3	1.6	2.2	-0.8	0.8	-1.5	-1.5	1.5	-1.5	-1.3	1.1	1.1	1.1
Locomotion velocity, session 8	1.0	1.2	2.0	-0.9	1.0	-1.4	-1.2	1.2	-1.4	-1.1	0.9	0.9	0.8
Locomotion distance, session 8	2.2	3.3	4.6	-0.3	0.3	-1.8	-2.1	2.0	-2.0	-2.1	2.0	2.0	2.0
Degree of sensitization distance	0.5	0.5	0.8	-0.9	0.7	-0.8	-0.9	0.9	-0.5	-0.8	0.1	0.5	0.4
Degree of sensitization stereotypy	1.6	1.8	2.6	-0.4	0.3	-1.3	-1.6	1.5	-1.4	-1.6	1.4	1.5	1.4
Conditioned locomotion	1.0	1.2	1.8	0.2	-0.2	1.0	1.4	-1.3	1.2	1.2	-1.2	-1.2	-1.2
Cocaine response after cond. corrected	0.5	0.5	1.8	1.3	-1.3	0.6	0.0	-0.0	0.2	-0.1	0.7	0.6	0.6
Cocaine response after cond. not corrected	0.4	0.4	1.2	1.0	-1.1	0.3	-0.3	0.3	-0.0	-0.3	0.8	0.7	0.7
Cocaine response before conditioning	0.6	0.7	1.1	-1.0	0.8	-1.0	-1.0	1.0	-0.8	-0.9	0.3	0.5	0.5
Saline control response	0.3	0.4	0.8	-0.7	0.5	-0.7	-0.9	0.8	-0.5	-0.7	0.2	0.4	0.4
Bone: connectivity density	1.3	2.1	3.1	0.3	-0.1	-1.1	-1.7	1.6	-1.4	-1.7	1.7	1.8	1.8
Bone: cortical apparent density	1.1	1.5	2.3	0.8	-0.8	1.5	1.5	-1.4	1.5	1.4	-0.9	-1.1	-1.1
Bone: cortical area	0.4	0.6	1.1	-0.2	0.4	0.5	0.8	-0.7	0.7	0.9	-1.1	-1.0	-1.0
Bone: cortical porosity	1.0	1.0	3.8	2.0	-1.9	0.7	0.3	-0.3	0.3	-0.1	1.0	0.6	0.8
Bone: cortical porosity	0.8	0.9	3.2	1.8	-1.8	0.8	0.5	-0.5	0.5	0.1	0.8	0.4	0.5
Bone: cortical thickness	1.7	2.8	4.6	1.4	-1.4	2.0	2.1	-2.0	2.0	1.8	-1.1	-1.4	-1.3
Bone: cortical thickness	2.1	2.4	6.1	2.5	-2.5	2.0	1.6	-1.5	1.5	1.0	0.2	-0.3	-0.1
Bone: cortical tissue density	0.9	1.2	1.8	0.7	-0.8	1.3	1.3	-1.3	1.3	1.2	-0.7	-1.0	-0.9
Condit. Reinf. active minus inactive responses	0.6	0.6	2.3	1.4	-1.5	1.1	0.4	-0.4	0.8	0.2	0.4	0.2	0.3
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.3	1.1	-1.1	1.0	0.3	-0.3	0.7	0.3	0.3	0.1	0.2
Condit. Reinf. active responses	0.4	0.5	2.0	1.2	-1.4	0.8	0.2	-0.3	0.6	0.0	0.4	0.3	0.4
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.1	-0.2	0.1	0.2	-0.2	0.3	0.1	-0.2	-0.1	-0.1
Incentive salience index mean	0.8	1.0	3.7	1.8	-1.9	1.0	0.2	-0.3	0.7	-0.0	0.8	0.6	0.7
Condit. Reinf. lever presses	1.4	1.9	5.6	2.2	-2.4	0.7	-0.3	0.2	0.1	-0.7	1.7	1.3	1.5
Condit. Reinf. active minus inactive responses	0.3	0.4	1.4	1.0	-1.2	0.8	0.2	-0.2	0.4	-0.1	0.6	0.4	0.4
Condit. Reinf. active-inactive response ratio	0.5	0.6	1.8	1.2	-1.3	1.1	0.5	-0.5	0.8	0.3	0.3	0.1	0.1
Condit. Reinf. active responses	0.1	0.2	0.6	0.7	-0.8	0.6	0.0	-0.1	0.1	-0.1	0.5	0.4	0.4
Condit. Reinf. inactive responses	0.1	0.1	0.5	-0.7	0.7	-0.2	-0.0	0.0	-0.2	-0.0	-0.3	-0.2	-0.3
Condit. Reinf. lever presses	0.6	0.8	1.2	-0.2	0.1	0.8	1.0	-0.9	1.0	1.0	-1.1	-1.0	-1.0
Condit. Reinf. lever reinforcers received	0.1	0.1	0.4	0.5	-0.6	0.7	0.2	-0.2	0.2	0.0	0.3	0.2	0.2
Conditioned reinforcement - actives	0.7	0.7	1.4	-0.8	0.8	-1.0	-0.9	1.0	-1.2	-0.9	0.4	0.6	0.5
Conditioned reinforcement - inactives	1.0	1.2	3.2	-1.8	1.4	-1.5	-1.2	1.0	-0.7	-0.9	-0.5	0.3	0.2
Conditioned locomotion	0.4	0.5	1.4	-1.1	1.2	-0.5	0.1	-0.0	-0.2	0.4	-1.0	-0.7	-0.8
Patch foraging indifference point 0 sec	0.9	1.4	3.6	1.6	-1.9	1.9	0.8	-0.9	1.4	0.6	0.1	-0.1	0.1
Patch foraging indifference point AUC	0.9	1.0	3.1	-1.5	1.8	-0.7	-0.3	0.3	-0.1	0.4	-1.4	-0.9	-1.0
Delay disc. indifference point, 0s delay	1.3	1.4	2.3	-1.5	1.4	-1.5	-1.4	1.4	-1.3	-1.0	0.5	0.6	0.5
Delay disc. indifference point, 16s delay	0.2	0.2	0.7	-0.7	0.8	-0.4	-0.0	0.1	-0.4	0.2	-0.2	-0.4	-0.4
Delay disc. indifference point, 2s delay	0.2	0.2	0.4	0.0	-0.1	0.6	0.6	-0.5	0.7	0.5	-0.3	-0.5	-0.5
Delay disc. indifference point, 24s delay	0.6	0.6	1.2	0.9	-0.9	1.1	0.8	-0.8	0.9	0.7	-0.2	-0.4	-0.3
Delay disc. indifference point, 4s delay	0.3	0.3	0.9	-0.9	0.7	-0.8	-0.5	0.5	-0.3	-0.4	-0.1	0.0	-0.0
Delay disc. indifference point, 8s delay	0.0	0.0	0.0	-0.1	0.1	-0.0	0.1	-0.1	0.1	0.1	0.1	-0.1	-0.1
Indifference point function ln k	2.6	3.6	11.4	3.1	-3.4	2.4	1.6	-1.6	1.2	0.7	1.4	0.5	0.6
Indifference point function log k	2.6	3.6	11.4	3.1	-3.4	2.4	1.6	-1.6	1.2	0.7	1.4	0.5	0.6
Patch foraging total patch changes 0 sec	0.6	0.9	2.5	1.3	-1.5	1.6	0.6	-0.7	1.3	0.5	-0.0	-0.1	0.0
Patch foraging total patch changes 12 sec	0.5	0.6	1.9	-1.4	1.3	-0.8	-0.7	0.7	-0.1	-0.2	-0.9	-0.3	-0.3
Patch foraging total patch changes 18 sec	0.2	0.2	0.6	-0.8	0.6	-0.3	-0.5	0.6	-0.0	-0.2	-0.4	-0.1	-0.1
Patch foraging total patch changes 24 sec	0.3	0.4	0.9	-1.0	0.9	0.1	0.1	0.0	0.4	0.6	-1.0	-0.7	-0.7
Patch foraging total patch changes 6 sec	0.6	0.9	2.9	-1.7	1.6	-0.5	-0.3	0.3	0.3	0.3	-1.4	-0.8	-0.9
Patch foraging time to switch 0 sec	1.0	1.5	2.9	-1.5	1.4	-1.7	-1.4	1.3	-1.3	-1.2	0.3	0.6	0.5
Patch foraging water rate 0 sec	0.5	0.8	1.7	0.6	-0.6	1.2	1.3	-1.1	1.0	1.1	-0.5	-0.7	-0.6
Patch foraging water rate 12 sec	0.5	0.7	1.1	-0.4	0.4	-0.8	-0.8	1.1	-1.0	-0.9	1.0	0.9	0.9
Patch foraging water rate 18 sec	0.7	0.9	2.8	0.9	-1.1	0.2	-0.2	0.5	-0.6	-0.8	1.7	1.2	1.2
Patch foraging water rate 24 sec	0.1	0.1	0.3	-0.6	0.5	-0.4	0.2	0.2	-0.4	-0.1	-0.1	0.0	-0.1
Patch foraging water rate 6 sec	0.1	0.1	0.8	-0.1	-0.1	0.3	0.9	-0.6	0.1	0.4	0.2	-0.2	-0.2
Seeking ratio, delayed vs. immediate footshock	0.7	0.8	1.2	0.5	-0.4	1.0	1.1	-1.0	1.0	1.1	-0.7	-0.9	-0.8
Distance traveled before self-admin	0.4	0.4	0.9	-1.0	0.9	-0.1	0.4	-0.3	0.2	0.6	-0.6	-0.9	-1.0
Distance traveled after self-admin	3.1	3.4	7.9	-2.6	2.8	-2.7	-1.7	1.9	-1.9	-1.4	-0.0	0.3	0.2
Extensor digitorum longus weight	2.5	9.7	17.9	-3.5	3.4	-4.2	-3.6	3.6	-3.6	-3.0	1.3	1.9	1.7
Bone: elastic displacement	0.6	0.7	1.0	-0.0	0.2	0.6	0.9	-0.8	0.9	1.0	-1.0	-1.0	-1.0
Bone: elastic work	1.4	1.8	2.8	0.8	-0.6	1.4	1.7	-1.5	1.6	1.6	-1.2	-1.3	-1.3
Bone: endosteal estimation	1.4	3.0	9.2	-2.8	3.0	-2.1	-1.5	1.5	-1.5	-0.8	-0.8	-0.1	-0.3
Bone: endosteal perimeter	1.4	2.9	8.7	-2.7	3.0	-2.1	-1.6	1.6	-1.6	-1.0	-0.5	0.1	-0.1
Epididymis fat weight	3.2	7.4	12.3	-1.9	1.9	-3.2	-3.5	3.4	-2.9	-3.2	1.7	2.4	2.3
Delta time in closed arm before/after self-admin	0.4	0.3	0.9	-0.9	0.8	-0.7	-0.8	0.6	-0.7	-0.3	0.0	0.1	0.1
Delta time in open arm before/after self-admin	0.6	0.5	1.1	-0.8	0.8	-1.0	-0.9	1.0	-0.6	-0.7	0.1	0.4	0.3
Diff in mean of infusions in LGA sessions	0.5	0.5	1.0	0.7	-0.8	0.1	-0.7	0.5	-0.3	-0.8	0.9	0.9	1.0
Delay discount exponential model param	0.1	0.1	0.1	0.0	0.1	-0.3	-0.4	0.3	-0.3	-0.4	0.1	0.3	0.3
Extinction: sum of active levers before priming	2.1	2.1	3.4	0.3	-0.3	-1.2	-1.7	1.6	-1.4	-1.8	1.7	1.7	1.7
Active lever presses in extinction session 6	1.3	1.2	2.2	-0.4	0.4	-1.2	-1.5	1.2	-1.3	-1.3	1.1	1.1	1.1
Bone: final force	0.3	0.4	0.9	-0.8	0.9	-0.9	-0.7	0.8	-0.6	-0.6	-0.1	0.2	0.2
Bone: final moment	0.3	0.4	1.1	-1.0	1.1	-0.9	-0.6	0.7	-0.6	-0.4	-0.3	0.1	-0.0
Food consumed during 24 hour testing period	0.3	0.4	1.3	1.1	-1.1	0.7	0.3	-0.3	0.0	-0.0	0.8	0.4	0.5
Glucose	2.2	3.4	7.0	-1.2	1.1	0.8	1.7	-1.6	1.8	1.9	-2.6	-2.3	-2.4
Heart weight	0.7	0.9	1.6	-1.1	0.8	-1.2	-1.3	1.2	-0.9	-1.1	0.4	0.6	0.6
Delay discount hyperbolic model param	0.1	0.1	0.1	0.2	-0.1	-0.2	-0.3	0.3	-0.3	-0.3	0.1	0.4	0.4
Intermittent access intake day 1-15 change	1.1	1.1	2.6	-1.4	1.6	-0.6	0.3	-0.3	0.5	0.7	-1.6	-1.2	-1.3
Intermittent access intake escalation	1.2	1.1	2.4	-1.3	1.5	-0.4	0.6	-0.4	0.4	0.9	-1.5	-1.3	-1.4
Intermittent access intake escalation 2	1.6	1.6	2.8	-0.7	1.0	0.3	1.4	-1.1	0.9	1.4	-1.6	-1.6	-1.7
Intermitt. access day 1 inactive lever presses	1.2	1.3	3.1	-0.9	0.6	0.2	1.0	-0.9	1.3	1.0	-1.8	-1.4	-1.4
Intermitt. access day 15 inactive lever presses	0.1	0.1	0.3	0.5	-0.4	0.3	0.1	-0.2	0.5	-0.0	-0.1	0.1	0.1
Intermitt. access escalation Index	1.9	1.7	2.7	0.3	-0.3	-0.8	-1.6	1.6	-1.1	-1.5	1.5	1.5	1.6
Intermittent access day 1 total infusions	1.3	1.6	2.5	-1.5	1.4	-1.6	-1.5	1.3	-1.5	-1.3	0.3	0.7	0.7
Intermittent access day 15 total infusions	2.4	2.7	8.6	-2.9	2.9	-2.1	-1.1	1.1	-1.2	-0.6	-1.1	-0.4	-0.6
Intermittent access terminal intake (last 3 days)	2.3	2.5	5.5	-2.3	2.3	-2.1	-1.7	1.5	-1.6	-1.3	-0.2	0.5	0.3
Intermittent access total infusions	1.4	1.6	3.9	-1.9	2.0	-1.7	-1.1	1.0	-1.3	-0.8	-0.3	0.2	0.0
Intermittent access day 1 locomotion	1.5	1.6	4.2	-2.0	2.0	-1.7	-1.1	1.1	-1.3	-0.9	0.0	0.3	0.2
Intermittent access day 15 total locomotion	0.9	0.9	3.6	-1.7	1.9	-1.1	-0.2	0.2	-0.6	-0.1	-0.8	-0.5	-0.6
Intermittent access total locomotion	0.7	0.8	2.1	-1.5	1.5	-1.3	-0.6	0.5	-0.9	-0.6	-0.3	0.0	-0.1
Intermittent access standard deviation	2.5	2.7	9.1	-2.7	3.0	-1.6	-0.1	0.3	-0.4	0.4	-1.9	-1.3	-1.5
Left kidney weight	0.0	0.1	0.4	-0.2	0.6	-0.3	-0.0	0.1	-0.1	0.2	-0.3	-0.4	-0.4
Right kidney weight	0.0	0.0	0.1	0.0	0.4	-0.3	0.1	-0.1	-0.1	0.2	-0.2	-0.3	-0.3
Cocaine induced anxiety	1.3	1.5	2.4	1.5	-1.2	1.5	1.4	-1.4	1.3	1.3	-0.7	-0.9	-0.8
Post-drug Anxiety	0.5	0.5	1.4	1.2	-1.0	0.9	0.5	-0.6	1.0	0.4	-0.3	-0.2	-0.2
Baseline Anxiety	0.5	0.5	1.1	-1.0	0.8	-0.8	-0.9	0.8	-0.5	-0.8	0.0	0.4	0.4
Tail length	2.5	7.6	12.1	0.5	-0.6	-1.7	-3.2	3.1	-2.8	-3.2	3.3	3.4	3.5
Length with tail	1.5	5.5	9.9	1.3	-1.1	-1.2	-2.3	2.3	-2.2	-2.6	3.1	3.0	3.1
Length without tail	1.3	2.8	5.4	0.8	-0.6	-1.2	-1.6	1.6	-1.7	-1.9	2.3	2.0	2.0
Times rat made contact with spout	0.7	0.8	1.9	1.4	-1.4	1.2	0.8	-0.8	1.0	0.6	0.0	-0.1	-0.0
Lifetime Intake	2.1	2.4	5.8	-2.4	2.4	-2.1	-1.4	1.3	-1.6	-1.1	-0.4	0.3	0.1
Liver weight, left	0.4	0.7	1.3	0.6	-0.8	-0.3	-0.6	0.6	-0.8	-0.8	1.1	1.1	1.2
Liver weight, right	1.0	1.6	2.4	-0.1	0.4	-1.3	-1.5	1.5	-1.6	-1.5	1.3	1.4	1.4
Locomotor activity	0.4	0.7	1.4	-1.1	0.9	-1.2	-0.9	1.0	-0.8	-0.8	0.2	0.5	0.4
Locomotor testing distance	1.8	3.0	6.8	-2.6	2.5	-2.4	-1.7	1.8	-1.7	-1.3	-0.1	0.5	0.3
Locomotor testing rearing	1.6	2.5	7.2	-2.7	2.6	-2.1	-1.5	1.5	-1.3	-0.9	-0.7	0.0	-0.2
Locomotion in novel chamber	2.3	2.8	5.8	-1.9	2.0	-0.2	1.3	-1.2	0.8	1.3	-2.4	-2.0	-2.2
Locomotion in novel chamber post-restriction	0.4	0.4	0.8	0.3	-0.2	0.7	0.7	-0.8	0.9	0.7	-0.7	-0.7	-0.7
Fecal boli incidents, locomotor time 1	0.2	0.3	0.7	0.9	-0.7	0.8	0.5	-0.5	0.2	0.3	0.3	-0.1	-0.0
Change in fecal boli incidents, locomotor task	0.4	0.4	0.7	0.7	-0.7	0.8	0.6	-0.6	0.7	0.6	-0.3	-0.3	-0.3
Time >=10cm from walls, locomotor time 1	0.1	0.2	0.4	0.5	-0.6	0.4	0.4	-0.5	0.5	0.3	0.2	-0.0	0.0
Bouts of movement, locomotor time 1	0.4	0.4	1.8	1.3	-1.2	0.7	0.2	-0.2	0.2	0.2	0.7	0.3	0.4
Total resting periods, locomotor time 1	1.0	1.0	3.4	1.9	-1.7	1.4	0.7	-0.7	0.8	0.6	0.5	0.1	0.2
Rest time, locomotor task time 1	0.6	0.6	1.4	0.5	-0.5	1.2	0.9	-0.9	0.9	0.9	-0.5	-0.7	-0.6
Distance moved, locomotor task time 1	0.7	0.7	1.9	-1.2	1.1	-1.4	-0.9	0.8	-0.7	-0.8	0.0	0.3	0.3
Vertical activity count, locomotor time 1	0.9	0.9	2.0	-1.3	1.1	-1.4	-1.0	1.1	-0.9	-1.0	0.2	0.5	0.4
Time >=10cm from walls, locomotor time 2	0.4	0.4	0.8	0.7	-0.8	0.9	0.7	-0.7	0.8	0.5	0.1	-0.2	-0.2
Bouts of movement, locomotor time 2	0.7	0.7	1.7	1.3	-1.3	1.2	0.7	-0.8	0.9	0.6	0.1	-0.2	-0.1
Total resting periods, locomotor time 2	0.4	0.4	1.4	1.2	-1.1	0.9	0.5	-0.5	0.5	0.4	0.4	0.1	0.1
Rest time, locomotor task time 2	0.7	0.8	1.4	1.0	-1.0	1.2	1.1	-1.1	0.8	0.9	-0.2	-0.5	-0.4
Distance moved, locomotor task time 2	1.0	1.1	3.3	-1.8	1.7	-1.5	-0.9	0.9	-0.8	-0.6	-0.4	-0.1	-0.2
Vertical activity count, locomotor time 2	0.4	0.5	1.1	-1.1	0.9	-0.9	-0.7	0.7	-0.6	-0.6	0.0	0.2	0.1
Light reinforcement 1	0.8	1.4	3.5	-1.9	1.6	-1.6	-1.1	1.1	-1.0	-1.0	-0.1	0.3	0.2
Light reinforcement 2	0.1	0.1	0.4	-0.6	0.6	-0.2	0.1	-0.1	-0.1	0.2	-0.5	-0.3	-0.4
Bone: marrow area	1.3	2.9	9.0	-2.8	3.0	-2.1	-1.5	1.5	-1.5	-0.8	-0.8	-0.1	-0.3
Bone: maximum diameter	0.4	0.7	2.4	-1.3	1.5	-0.6	-0.1	0.2	-0.2	0.2	-1.0	-0.7	-0.7
Bone: maximum force	0.3	0.5	1.4	-1.0	1.2	-1.0	-0.7	0.7	-0.6	-0.5	-0.3	0.1	-0.0
Bone: maximum moment	0.3	0.6	1.9	-1.3	1.4	-1.0	-0.6	0.6	-0.5	-0.3	-0.6	-0.1	-0.2
Mean time between licks in bursts	1.7	2.3	3.6	-0.9	0.9	-1.7	-1.8	1.7	-1.9	-1.7	1.4	1.5	1.4
Mean num. licks in bursts	0.1	0.1	0.4	0.6	-0.5	0.1	-0.2	0.1	-0.1	-0.2	0.6	0.4	0.5
Cd content in liver	0.9	1.0	1.4	-1.1	0.9	-1.1	-1.2	1.0	-1.1	-1.1	0.6	0.8	0.7
Co content in liver	0.2	0.2	0.5	-0.1	0.3	-0.4	-0.5	0.6	-0.7	-0.5	0.5	0.5	0.5
Cu content in liver	1.4	1.7	3.9	1.8	-2.0	1.8	1.3	-1.3	1.4	0.9	0.1	-0.3	-0.2
Fe content in liver	0.5	0.6	1.2	0.7	-0.8	-0.3	-0.6	0.6	-0.5	-0.8	1.1	1.0	1.0
K content in liver	0.7	0.7	1.7	0.9	-0.6	-0.2	-0.7	0.6	-0.8	-0.7	1.3	1.0	1.0
Mg content in liver	0.0	0.0	0.1	-0.1	0.2	0.1	0.1	-0.1	0.1	0.2	-0.2	-0.3	-0.3
Mn content in liver	0.8	0.9	3.3	1.8	-1.6	1.2	0.6	-0.7	0.5	0.4	0.6	0.2	0.3
Na content in liver	0.1	0.2	0.3	-0.4	0.4	0.0	0.3	-0.3	0.2	0.4	-0.4	-0.5	-0.5
Rb content in liver	0.4	0.5	1.2	-0.9	1.1	-0.9	-0.7	0.8	-0.7	-0.5	-0.0	0.2	0.1
Se content in liver	1.0	1.2	2.0	0.7	-0.7	1.4	1.4	-1.3	1.3	1.2	-0.8	-1.0	-0.9
Sr content in liver	1.5	1.3	2.1	-1.1	1.1	-1.5	-1.4	1.4	-1.3	-1.2	0.7	0.9	0.8
Zn content in liver	0.2	0.2	0.5	0.2	-0.2	0.5	0.5	-0.5	0.7	0.5	-0.4	-0.5	-0.5
Bone: minimum diameter	1.0	1.8	4.8	-2.0	2.2	-1.7	-1.3	1.3	-1.4	-0.9	-0.2	0.2	0.1
Time in familiar zone, hab. session 1	0.2	0.2	0.6	-0.8	0.6	-0.3	0.2	-0.1	0.3	0.2	-0.7	-0.5	-0.6
Time in novel zone, hab. session 1	0.2	0.2	0.8	0.9	-0.6	0.6	0.0	-0.1	-0.0	-0.0	0.5	0.4	0.5
Total zone transitions, hab. session 1	2.8	3.9	10.4	-3.2	2.9	-2.8	-1.9	1.9	-1.7	-1.5	-0.1	0.4	0.2
Total locomotion distance, hab. session 1	0.3	0.4	1.0	-1.0	0.7	-0.9	-0.7	0.7	-0.5	-0.6	0.1	0.3	0.3
Locomotion velocity, hab. session 1	0.3	0.4	1.3	-1.1	0.8	-1.0	-0.6	0.6	-0.5	-0.5	-0.0	0.1	0.1
Time in familiar zone, hab. session 2	0.3	0.3	0.8	0.8	-0.9	0.5	-0.1	0.1	-0.1	-0.1	0.7	0.4	0.5
Time in novel zone, hab. session 2	0.5	0.5	0.9	-0.1	0.2	0.4	0.8	-0.8	0.8	0.7	-0.9	-0.8	-0.8
Total zone transitions, hab. session 2	1.7	2.3	4.2	-1.9	1.5	-2.0	-1.8	1.7	-1.5	-1.5	0.5	0.9	0.8
Total locomotion distance, hab. session 2	0.3	0.4	0.9	-1.0	0.6	-0.9	-0.8	0.7	-0.6	-0.7	0.1	0.4	0.3
Locomotion velocity, hab. session 2	0.3	0.5	1.0	-1.0	0.7	-1.0	-0.8	0.7	-0.7	-0.6	0.1	0.3	0.3
Novel to familiar place preference ratio	0.2	0.2	0.4	-0.6	0.4	-0.1	0.2	-0.2	0.3	0.3	-0.7	-0.5	-0.5
Novelty place preference	0.0	0.0	0.1	-0.3	0.1	0.0	0.1	-0.0	0.2	0.1	-0.3	-0.2	-0.2
Time in novel zone, NPP test	0.0	0.0	0.0	-0.1	-0.0	0.0	-0.1	0.1	0.1	-0.1	-0.1	0.0	0.0
Total zone transitions, NPP test	1.9	2.7	5.9	-2.4	2.1	-2.4	-1.8	1.8	-1.5	-1.4	0.1	0.6	0.5
Total locomotion distance, NPP test	0.2	0.3	1.1	-1.1	0.8	-0.5	-0.1	0.1	0.1	0.2	-0.8	-0.5	-0.6
Locomotion velocity, NPP test	0.5	0.6	1.5	-1.1	0.8	-0.2	0.4	-0.4	0.5	0.6	-1.2	-1.0	-1.0
Intraocular pressure	0.8	1.1	3.4	-1.8	1.8	-0.5	0.0	0.0	0.2	0.4	-1.3	-1.0	-1.2
Delta distance traveled before/after self-admin	3.0	3.3	6.1	-1.5	1.6	-2.5	-2.1	2.1	-2.1	-2.0	0.9	1.5	1.3
Delta ambulatory time before/after self-admin	1.9	2.1	4.1	-1.1	1.2	-2.0	-1.7	1.7	-1.6	-1.7	0.7	1.2	1.1
Parametrial fat weight	10.8	21.0	32.0	-2.8	2.7	-5.2	-5.7	5.6	-5.3	-5.3	3.7	4.3	4.1
Pavlov. Cond. lever latency	1.1	1.4	4.5	-1.9	2.1	-1.4	-0.8	0.9	-1.3	-0.6	-0.2	0.0	-0.1
Pavlov. Cond. magazine entry latency	1.8	2.3	7.8	2.8	-2.8	1.7	0.7	-0.8	1.0	0.3	1.0	0.5	0.7
Pavlov. Cond. change in total contacts	1.5	1.6	3.0	1.2	-1.6	1.5	1.4	-1.4	1.7	1.2	-0.7	-0.8	-0.7
Pavlov. Cond. index score	1.2	1.5	5.7	2.2	-2.4	1.3	0.4	-0.5	0.8	0.1	0.9	0.6	0.7
Pavlov. Cond. latency score	1.4	1.7	6.4	2.4	-2.5	1.2	0.3	-0.5	0.7	-0.0	1.1	0.8	0.9
Pavlov. Cond. lever contacts	0.8	0.9	3.5	1.6	-1.9	1.0	0.5	-0.6	1.0	0.3	0.3	0.2	0.3
Pavlov. Cond. magazine entry number	0.9	1.2	3.8	-1.8	2.0	-1.4	-0.7	0.8	-1.1	-0.5	-0.3	-0.1	-0.2
Pavlov. Cond. intertrial magazine entries	1.7	2.0	6.8	-2.6	2.3	-1.9	-1.1	1.2	-1.1	-0.8	-0.5	-0.0	-0.2
Pavlov. Cond. lever-magazine prob. diff.	1.1	1.4	5.2	2.1	-2.3	1.2	0.5	-0.6	0.9	0.2	0.7	0.4	0.6
Pavlov. Cond. response bias	1.1	1.3	4.8	1.9	-2.2	1.3	0.6	-0.7	1.1	0.4	0.4	0.2	0.3
Pavlov. Cond. lever latency	2.0	2.7	4.2	-0.5	0.5	-1.6	-2.0	2.0	-2.0	-1.8	1.6	1.7	1.7
Pavlov. Cond. magazine entry latency	0.7	0.8	1.4	0.9	-0.7	1.2	1.1	-1.1	1.1	1.0	-0.5	-0.7	-0.7
Pavlov. Cond. change in total contacts	0.7	0.9	1.5	0.9	-0.7	1.2	1.2	-1.2	1.1	1.0	-0.6	-0.8	-0.8
Pavlov. Cond. index score	1.6	2.1	2.9	0.2	0.0	1.3	1.7	-1.7	1.6	1.7	-1.6	-1.7	-1.7
Pavlov. Cond. latency score	2.0	2.5	3.5	0.1	0.1	1.4	1.9	-1.8	1.8	1.9	-1.8	-1.9	-1.9
Pavlov. Cond. lever contacts	0.8	1.0	1.5	0.0	-0.1	0.9	1.2	-1.2	1.2	1.1	-1.1	-1.1	-1.1
Pavlov. Cond. magazine entry number	0.8	0.9	1.4	-0.6	0.3	-1.1	-1.2	1.1	-1.1	-1.1	0.8	1.0	0.9
Pavlov. Cond. intertrial magazine entries	0.9	1.2	1.8	-0.9	0.6	-1.3	-1.3	1.3	-1.2	-1.2	0.8	1.0	0.9
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.1	2.9	0.3	-0.1	1.4	1.7	-1.7	1.7	1.7	-1.5	-1.7	-1.6
Pavlov. Cond. response bias	1.0	1.3	2.0	0.4	-0.4	1.2	1.4	-1.4	1.4	1.3	-1.0	-1.2	-1.1
Time in closed arm before self-admin	0.7	0.8	1.8	1.3	-1.3	0.3	-0.5	0.4	-0.1	-0.8	1.1	1.0	1.1
Time in closed arm after self-admin	0.0	0.0	0.1	0.2	-0.3	0.3	-0.1	-0.1	0.1	0.0	0.1	-0.0	0.0
Time in open arm before self-admin	1.6	1.7	2.6	0.0	-0.0	1.2	1.5	-1.5	1.4	1.6	-1.4	-1.6	-1.5
Time in open arm after self-admin	0.9	1.0	2.1	-1.5	1.4	-0.4	0.5	-0.3	0.4	0.7	-1.4	-1.1	-1.2
Bone: periosteal estimation	0.6	1.2	4.4	-1.9	2.1	-1.2	-0.6	0.7	-0.7	-0.2	-0.9	-0.5	-0.6
Bone: periosteal perimeter	0.3	0.6	2.3	-1.2	1.5	-0.6	-0.5	0.5	-0.5	-0.1	-0.6	-0.3	-0.4
Bone: post-yield work	0.6	0.9	1.4	-0.0	0.1	-0.9	-1.2	1.1	-1.0	-1.1	0.9	1.1	1.0
Progressive ratio test 1 active lever presses	1.3	1.3	2.3	-1.1	0.8	-1.3	-1.4	1.1	-1.5	-1.3	0.8	1.0	0.9
Progressive ratio test 1 breakpoint	1.9	2.0	3.4	-1.1	0.8	-1.6	-1.9	1.4	-1.7	-1.7	1.1	1.3	1.3
Progressive ratio test 1 inactive lever presses	0.8	0.8	2.5	-1.6	1.4	-1.5	-0.6	0.5	-0.9	-0.6	-0.0	0.2	-0.0
Progressive ratio test 2 active lever presses	0.6	0.6	1.2	-0.6	0.8	-1.1	-0.9	0.8	-1.0	-0.9	0.4	0.6	0.5
Progressive ratio test 2 breakpoint	0.3	0.4	0.8	-0.4	0.5	-0.9	-0.6	0.5	-0.9	-0.7	0.5	0.5	0.4
Progressive ratio test 2 inactive lever presses	1.3	1.5	4.2	-2.1	1.9	-1.7	-1.1	1.0	-1.0	-1.0	-0.4	0.2	0.1
Incentive Sensitization - Responses	0.1	0.1	0.3	-0.1	0.2	-0.6	-0.3	0.4	-0.4	-0.4	0.1	0.3	0.2
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	-0.1	0.2	-0.6	-0.3	0.3	-0.4	-0.4	0.1	0.2	0.2
Sum of active levers in priming session hrs 5-6	1.8	1.8	3.6	1.0	-1.0	-0.4	-1.3	1.2	-1.0	-1.4	1.9	1.7	1.7
Progressive ratio	0.2	0.2	0.7	-0.7	0.9	-0.5	-0.4	0.3	-0.1	0.0	-0.6	-0.4	-0.4
Food seeking constrained by brief footshock	0.1	0.1	0.3	0.4	-0.3	0.5	0.4	-0.3	0.3	0.5	-0.2	-0.3	-0.3
Seeking ratio, punishment vs. effort	0.4	0.5	1.1	1.0	-1.1	0.9	0.8	-0.7	0.4	0.4	0.3	0.1	0.2
Retroperitoneal fat weight	0.1	0.5	2.0	-1.4	1.1	-0.9	-0.1	0.2	-0.2	-0.1	-0.6	-0.4	-0.5
Reaction time number correct	0.2	0.2	0.4	-0.4	0.2	-0.6	-0.3	0.4	-0.6	-0.6	0.5	0.6	0.6
Reaction time mean minus median	1.0	1.3	2.2	0.3	-0.4	1.1	1.1	-1.2	1.5	1.2	-1.5	-1.2	-1.2
Reaction time mean minus median AUC	0.3	0.4	1.1	0.1	-0.1	0.6	0.5	-0.6	0.8	0.6	-1.0	-0.7	-0.7
Reaction time num false alarms	1.1	1.5	2.7	0.9	-1.0	1.6	1.3	-1.3	1.6	1.3	-0.9	-1.0	-0.9
Reaction time num false alarms AUC	0.9	1.2	2.0	0.7	-0.7	1.4	1.2	-1.3	1.4	1.2	-0.9	-1.0	-0.9
Reaction time trials correct on left	0.2	0.2	0.4	-0.4	0.2	-0.6	-0.3	0.4	-0.6	-0.6	0.5	0.6	0.6
Reaction time trials on left	0.2	0.2	0.3	-0.4	0.2	-0.5	-0.3	0.4	-0.6	-0.6	0.4	0.6	0.5
Reaction time mean	0.3	0.5	0.8	0.4	-0.4	0.8	0.7	-0.7	0.9	0.7	-0.8	-0.7	-0.7
Reaction time mean AUC	0.8	1.1	1.6	0.5	-0.5	1.1	1.1	-1.1	1.3	1.1	-1.2	-1.1	-1.0
Median of all reaction times	0.1	0.2	0.3	0.2	-0.2	0.5	0.4	-0.4	0.5	0.5	-0.6	-0.5	-0.5
Reaction time omissions	0.2	0.2	0.8	-0.9	0.8	-0.4	-0.4	0.3	-0.2	-0.2	-0.5	-0.1	-0.2
Reaction time false alarm rate	0.9	1.2	2.1	0.8	-0.8	1.4	1.1	-1.2	1.5	1.2	-0.9	-1.0	-1.0
Reaction time premature initiation rate	0.7	0.9	2.7	1.5	-1.7	1.3	0.6	-0.7	0.6	0.2	0.8	0.4	0.5
Reaction time premature initiations	0.4	0.6	1.9	1.2	-1.4	0.9	0.4	-0.4	0.2	-0.1	1.0	0.6	0.7
Std. dev. reaction times	1.4	1.9	3.0	0.9	-0.9	1.7	1.5	-1.5	1.7	1.4	-1.4	-1.3	-1.2
Reaction time trials completed	0.2	0.2	0.3	-0.4	0.2	-0.5	-0.3	0.4	-0.6	-0.6	0.4	0.6	0.5
Reaction time trials AUC	0.1	0.2	0.3	-0.3	0.2	-0.5	-0.2	0.4	-0.5	-0.5	0.4	0.6	0.5
Run reversals in cocaine runway, females	0.1	0.1	0.3	0.3	-0.4	0.3	0.5	-0.5	0.4	0.4	-0.3	-0.3	-0.3
Run reversals in cocaine runway, males	1.3	1.3	4.2	-2.0	2.0	-1.3	-0.2	0.3	-0.2	0.1	-1.1	-0.8	-1.0
Latency to leave start box in cocaine runway	0.1	0.1	0.3	0.4	-0.5	0.3	-0.0	0.0	0.1	0.1	0.2	0.1	0.2
Latency to leave start box in cocaine runway, F	0.3	0.4	0.9	0.9	-0.9	0.3	-0.4	0.4	-0.2	-0.3	0.7	0.7	0.8
Latency to leave start box in cocaine runway, M	0.2	0.1	0.3	-0.6	0.5	-0.5	-0.3	0.4	-0.4	-0.3	0.2	0.2	0.1
Std. dev. time between licks in bursts	0.5	0.6	1.0	-0.6	0.5	-0.9	-0.9	0.9	-1.0	-0.9	0.7	0.7	0.7
Total sessions with >9 infusions	1.5	1.7	3.0	-1.5	1.4	-1.7	-1.5	1.4	-1.7	-1.2	0.4	0.8	0.7
Short access day 1 total inactive lever presses	0.2	0.2	1.1	-1.0	0.5	-0.5	-0.5	0.3	0.1	-0.3	-0.4	-0.0	-0.0
Short access day 10 total inactive lever presses	0.0	0.0	0.1	0.4	-0.2	-0.1	0.3	-0.1	0.3	0.1	0.0	-0.0	-0.0
Short access day 1 total infusions	1.6	1.7	6.0	-2.4	2.3	-1.5	-0.8	0.6	-0.7	-0.2	-1.1	-0.6	-0.7
Short access day 10 total infusions	1.0	1.1	2.6	-1.6	1.4	-1.4	-1.1	0.9	-1.1	-0.9	-0.2	0.4	0.3
Short access total infusions	2.1	2.4	7.5	-2.7	2.5	-1.9	-1.3	1.1	-1.2	-0.8	-0.8	-0.1	-0.3
Short access day 1 locomotion	0.6	0.7	2.5	-1.6	1.3	-0.8	-0.1	0.0	-0.2	0.1	-0.9	-0.6	-0.7
Short access day 10 total locomotion	0.6	0.7	2.5	-1.6	1.4	-1.0	-0.1	0.3	-0.4	-0.0	-0.7	-0.5	-0.6
Short access total locomotion	0.5	0.5	2.1	-1.5	1.3	-0.9	-0.2	0.1	-0.4	-0.0	-0.6	-0.4	-0.5
One hour access (0.3 mA shock)	0.9	1.1	2.3	-1.4	1.5	-1.5	-1.0	1.1	-1.2	-0.9	-0.1	0.3	0.2
Compulsive drug intake	0.4	0.4	1.6	1.2	-1.3	0.7	0.1	-0.0	0.4	0.0	0.6	0.3	0.4
One hour access (shock baseline)	1.2	1.4	3.6	-1.7	1.9	-1.7	-1.0	1.0	-1.4	-0.8	-0.1	0.3	0.1
Social response proportion	2.3	2.5	5.3	1.9	-1.9	-0.0	-0.9	0.7	-0.7	-1.5	2.3	2.0	2.0
Social responses	2.0	2.6	4.5	-0.8	0.6	-1.8	-2.1	1.9	-1.7	-2.0	1.4	1.7	1.6
Social time	1.5	2.0	3.2	-0.3	0.1	-1.5	-1.7	1.5	-1.5	-1.8	1.5	1.7	1.6
Soleus weight	3.6	10.6	14.4	-0.1	0.2	-3.0	-3.7	3.6	-3.8	-3.7	3.8	3.7	3.7
Bone: stiffness	2.1	3.4	5.1	-0.6	0.7	-2.0	-2.3	2.2	-2.1	-2.2	1.6	1.9	1.8
Tibialis anterior weight	3.3	11.2	17.1	-2.3	2.2	-4.0	-4.1	4.0	-3.9	-3.8	2.4	3.0	2.8
Time to tail flick, vehicle, before self-admin	1.0	1.1	2.0	0.5	-0.7	-0.4	-1.1	1.0	-0.7	-1.2	1.3	1.3	1.4
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.3	-0.6	0.4	-0.4	-0.3	0.2	-0.1	-0.2	0.1	0.0	0.0
Time to tail flick, test, before self-admin	1.9	1.9	5.9	2.4	-2.4	1.8	1.1	-1.0	1.0	0.5	0.6	0.2	0.3
Time to tail flick, test, after self-admin	0.5	0.5	2.0	1.2	-1.4	0.8	0.4	-0.4	0.4	0.0	0.8	0.3	0.4
Delta time to tail flick, vehicle, before/after SA	0.9	0.9	2.2	-1.5	1.3	-0.3	0.6	-0.5	0.2	0.7	-1.2	-1.1	-1.2
Delta time to tail flick, test, before/after SA	0.7	0.6	2.0	-1.4	1.3	-1.1	-0.6	0.6	-0.6	-0.3	-0.1	-0.1	-0.2
Tibia length	0.6	1.8	4.4	2.1	-1.9	0.6	-0.5	0.3	-0.4	-0.8	1.8	1.5	1.6
Ambulatory time before self-admin	0.3	0.3	0.7	-0.4	0.6	0.2	0.4	-0.4	0.3	0.6	-0.8	-0.8	-0.8
Ambulatory time after self-admin	2.1	2.3	4.4	-1.3	1.5	-2.1	-1.7	1.8	-1.8	-1.6	0.8	1.0	0.9
Bone: tissue strength	0.4	0.3	0.8	-0.6	0.6	-0.0	0.4	-0.4	0.5	0.5	-0.9	-0.7	-0.8
Total heroin consumption	2.4	2.8	4.9	1.0	-1.2	-0.6	-1.7	1.6	-1.1	-2.0	2.2	2.1	2.2
Bone: trabecular number	0.6	0.9	1.6	1.0	-0.9	0.0	-0.8	0.7	-0.5	-0.9	1.3	1.2	1.3
Bone: trabecular spacing	0.3	0.4	0.8	-0.9	0.8	-0.2	0.4	-0.3	0.2	0.5	-0.7	-0.8	-0.8
Bone: trabecular thickness	0.2	0.3	0.5	-0.0	0.0	-0.5	-0.6	0.6	-0.6	-0.7	0.5	0.6	0.6
Bone: trabecular tissue density	1.8	2.6	4.2	0.6	-0.8	1.6	2.0	-1.9	1.9	1.9	-1.4	-1.7	-1.6
Water consumed over 24 hours	1.8	2.1	6.5	2.5	-2.4	2.0	1.1	-1.1	1.0	0.6	0.9	0.3	0.5
Number of responses in last shaping day	0.6	0.6	1.6	-1.3	0.9	-0.4	0.6	-0.5	0.3	0.7	-1.1	-0.9	-1.0